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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T1154 | Rifaximin | DNA/RNA Synthesis , Antibacterial , Antibiotic | |
Rifaximin is an orally administered, semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity. Rifaximin binds to the beta-subunit of bacterial DNA-dependent RNA polymerase, inhibiting... | |||
T1305 | Ceftazidime | GR20263 | Antibacterial , Antibiotic |
Ceftazidime (GR20263) is a beta-lactam, cephalosporin antibiotic with bactericidal activity. | |||
T0234 | Methicillin sodium salt | Methicillin sodium,Meticillin sodium | Antibacterial , Antibiotic |
Methicillin sodium salt is the sodium salt form of methicillin, a semisynthetic beta-lactam penicillin antibiotic with beta-lactamase resistant activity. | |||
T8337 | Nequinate | Xanthine Oxidase , Parasite | |
Nequinate is an anticoccidial agent, preventing coccidiosis . | |||
T37514 | Hydroxy Dimetridazole | Drug Metabolite | |
Dimetridazole is a nitroimidazole-based compound with antibacterial and anticoccidial activity. It was once widely used in the treatment of parasitic infections in poultry, cattle, swine and farmed fish until suspected t... | |||
T8722 | IKIX1 | Antifungal | |
iKIX1 is an Pdr1-dependent gene activation. It re-sensitizes drug-resistant C. glabrata to azole antifungals in vitro and in animal models for disseminated and urinary tract C. glabrata infection. | |||
T11539 | HCV-IN-29 | HCV Protease | |
HCV-IN-29 is a hepatitis C virus (HCV) inhibitor. | |||
T4985 | Neticonazole Hydrochloride | Antifungal | |
Neticonazole Hydrochloride is an imidazole antifungal for the treatment of fungal skin infections. Neticonazole is reported as a potent exosome inhibitor which can block the activity of exosomes. | |||
T11541 | HCV-IN-30 | Others , HCV Protease | |
HCV-IN-30 is an HCV NS5A replication complex inhibitor (IC50s: 901 and 102 nM for genotypes 1a and 1b replicons). | |||
T20525 | Chloramphenicol palmitate | Antibacterial , Antibiotic | |
Chloramphenicol palmitate is a broad-spectrum antibiotic with activity against gram-positive and gram-negative bacteria. Chloramphenicol palmitate can be used in studies about acting as a bacterial selection agent in tra... | |||
T5477 | ELQ-300 | Parasite | |
ELQ-300 is bioavailable antimalarial agent, acts as an inhibitor of the reductive (Qi) site of the cytochrome bc1 complex (cyt bc1) | |||
T25268 | Coblopasvir | Others | |
Coblopasvir is a pan-genotypic non-structural protein 5A (NS5A) inhibitor. It can be used to study chronic hepatitis C virus infection. | |||
T1444 | Lomefloxacin | SC47111A | Topoisomerase , Antibacterial , Antibiotic |
Lomefloxacin (SC47111A) is a synthetic broad-spectrum fluoroquinolone with antibacterial activity. | |||
T0748 | Sulfameter | 5-Methoxysulfadiazine,Sulfametoxydiazine | DHFR , Antibacterial , Antibiotic |
Sulfameter (Sulfametoxydiazine) is a long-acting sulfonamide antibacterial agent used to treat urinary tract infections and leprosy. | |||
T60050 | ANT3310 | Antibacterial | |
ANT3310 is an inhibitor of broad-spectrum covalent Serine β-Lactamase with IC50s ranging from 1 nM to 175 nM for AmpC, CTX-M-15, TEM-1, OXA-48, OXA-23, and KPC-2. ANT3310 can be used in studies about bacterial infection. | |||
T10797 | Chlormidazole hydrochloride | Clomidazole hydrochloride | Antifungal |
Chlormidazole hydrochloride (Clomidazole hydrochloride) has inhibitory activity against many fungi and some gram-positive cocci. It can be applied in fungal and bacterial infections of skin and nails, including interdigi... | |||
T8371 | ML188 | Virus Protease , SARS-CoV | |
ML188 is a selective noncovalent SARS-CoV 3CLpro inhibitor(IC50 : 1.5 μM), with moderate MW and good enzyme and antiviral inhibitory activity. | |||
T0328 | Hexetidine | NSC-17764 | Antibacterial , Antifungal |
Hexetidine (NSC-17764) is a bactericidal and fungicidal antiseptic. It is used as a 0.1% mouthwash for local infections and oral hygiene. | |||
T6582 | Mezlocillin Sodium | Baycipen | Antibacterial , Antibiotic |
Mezlocillin Sodium (Baycipen) is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. | |||
T1883 | Des(benzylpyridyl) Atazanavi | HIV Protease | |
The N-dealkylated metabolite (M1) of Atazanavir, a HIV protease inhibitor. | |||
T0830 | Bithionol | Actamer | cAMP , Parasite |
Bithionol (Actamer), formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders. Approvals of the NDA's for bit... | |||
T1259 | Pyrantel pamoate | Pyrantel embonate | Others , Antibiotic , Parasite |
Pyrantel pamoate (Pyrantel embonate) is a depolarizing neuromuscular blocking agent. | |||
T19862 | Voxilaprevir | HCV Protease | |
Voxilaprevir is an inhibitor of hepatitis C virus (HCV) nonstructural (NS) protein 3/4A protease. | |||
T0395 | Pyrantel tartrate | Banminth | Antibiotic , Parasite |
Pyrantel tartrate (Banminth) is broad spectrum anthelmintic for livestock. | |||
T18928 | Brilliant Black BN | E 151 | Others , Virus Protease |
Brilliant Black BN (E 151) is an azo dye and a food colorant. It is a promising antiviral agent against EV71 infection via inhibiting the interaction between EV71 and its cellular uncoating factor cyclophilin A. | |||
T1647 | Ronidazole | Ronidazol,Ridzol | Antibacterial , Antibiotic , Parasite |
Ronidazole (Ronidazol) is an antiprotozoal and antimicrobial agent used mainly in veterinary practice. | |||
T1070 | Cefmetazole sodium | Sodium cefmetazole | Antibacterial , Antibiotic |
Cefmetazole sodium (Sodium cefmetazole) is a semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms. It has a high rate of efficacy in many types... | |||
T4382 | Proguanil hydrochloride | Paludrine hydrochloride,Chlorguanide hydrochloride,Chloroquanil | Others , Dehydrogenase , DNA/RNA Synthesis , Antifolate , Parasite |
Proguanil hydrochloride (Chloroquanil) is a biguanide compound which metabolizes in the body to form cycloguanil, an anti-malaria agent.Upon hydrolysis, Proguanil hydrochloride is converted to its active cyclic triazine ... | |||
T7766 | Remdesivir | GS-5734 | SARS-CoV , DNA/RNA Synthesis |
Remdesivir (GS-5734) is a nucleoside analog, a broad-spectrum antiviral compound that exerts its activity by inhibiting the RNA-dependent RNA polymerase of viruses. Remdesivir is active against Ebola, SARS, and MERS viru... | |||
T35427 | β-Lactamase-IN-2 | Antibacterial | |
β-Lactamase-IN-2 is an inhibitor of β-Lactamase with anti-microbial and anti-bacterial effects. | |||
T2411 | Luliconazole | NND 502 | Antibiotic , Antifungal |
Luliconazole (NND 502) is an Azole Antifungal. The mechanism of action of luliconazole is as a Cytochrome P450 2C19 Inhibitor. | |||
T37340 | N4-Acetylsulfamethoxazole | N-acetyl Sulfamethoxazole | Others |
N-acetyl Sulfamethoxazole is a metabolite of sulfamethoxazole, an antibiotic with antiviral activity, that can be detected in urine. | |||
T3279 | Silver sulfadiazine | Silvadene,Dermazin,Flamazine | DNA/RNA Synthesis , Antibacterial , Antibiotic |
Silver sulfadiazine (Dermazin) is a sulfonamide-based topical agent with antibacterial and antifungal activity. | |||
TQ0095 | Brincidofovir | CMX001,HDP-CDV | Others , Antiviral , HSV |
Brincidofovir (HDP-CDV) is an orally active, lipophilic form of cidofovir. It has enhanced activity compared to CDV against certain adenoviruses, herpesviruses, and orthopoxviruses. | |||
T15394 | Glyceryl monocaprate | 2,3-Dihydroxypropyl decanoate,DECANOIN,Monocaprin | Antibacterial , HSV |
Glyceryl monocaprate (2,3-Dihydroxypropyl decanoate) has inhibitory effect on Herpes Simplex Virus (HSV). It also offers an effective treatment for herpes labialiss. Glyceryl monocaprate is a capric acid against 1-monogl... | |||
T1623 | Lopinavir | ABT-378 | SARS-CoV , HIV Protease |
Lopinavir (ABT-378) is a peptidomimetic HIV protease inhibitor that retains activity against HIV protease with the Val 82 mutation. Lopinavir is less affected by binding to serum proteins than the structurally-related dr... | |||
T6349 | Sitafloxacin Hydrate | DU-6859a,DU6859a hydrate | Antibacterial , Antibiotic |
Sitafloxacin Hydrate (DU-6859a) is a fluoroquinolone antibiotic that shows promise in the treatment of Buruli ulcer. | |||
T1625 | Lomefloxacin hydrochloride | Lomefloxacin HCl,Okacyn,Maxaquin | Topoisomerase , Antibacterial , Antibiotic |
Lomefloxacin hydrochloride (Okacyn) inhibits DNA gyrase, a type II topoisomerase involved in the induction or relaxation of supercoiling during DNA replication. This inhibition leads to a decrease in DNA synthesis during... | |||
T7779 | Nelfinavir | AG1341 | HIV Protease |
Nelfinavir (AG1341) is an antiretroviral drug used in the treatment of the human immunodeficiency virus (HIV) (Ki=2 nM). Nelfinavir is a broad-spectrum, anticancer agent. | |||
T7330 | Nucleozin | Influenza Virus | |
Nucleozin targets influenza A nucleoprotein (NP), a multifunctional, RNA-binding protein necessary for virus replication. | |||
T31482 | Diloxanide | Diloxanid,RD 3803,RD3803,RD-3803,Diloxanida | Parasite |
Diloxanide (RD3803) is an endomoeba insecticide. It is considered to be the luminal agent of choice for patients with mild enteroamoebiasis or asymptomatic cysts. | |||
T22323 | Enoxaparin sodium | Thrombin | |
Enoxaparin sodium is a low-molecular-weight heparin (LMWH) that has recently been approved by the US FDA for use in patients with medically managed ST-segment myocardial infarction (STEMI), or STEMI with subsequent percu... | |||
T1646 | Famciclovir | BRL 42810 | DNA/RNA Synthesis , HSV |
Famciclovir (BRL 42810) is a Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor. The mechanism of action of famciclovir is as a DNA Polymerase Inhibitor, and DNA Polymerase Inhibitor. | |||
T12732 | Rezafungin | SP-3025,CD101,Biafungin | Others , Antifungal |
Rezafungin (SP-3025) is a broad-spectrum and long-lasting echinocandin with potent antifungal activity against Candida, Aspergillus and Pneumocystis. | |||
T1557 | Acetylspiramycin | Spiramycin II,Foromacidin B,ASPM,Spiramycin B | ribosome , Antibacterial , Antibiotic |
Acetylspiramycin (Spiramycin B) targets 50S ribosome to inhibit protein synthesis. | |||
T8139 | Sulfamethoxazole sodium | Ro 4-2130 sodium | Others , Antibacterial , Antibiotic |
Sulfamethoxazole sodium (Ro 4-2130 sodium) is a sulfonamide bacteriostatic antibiotic | |||
T25268L | Coblopasvir dihydrochloride | Coblopasvir dihydrochloride(1312608-46-0 Free base) | HCV Protease |
Coblopasvir dihydrochloride can be used to study chronic HCV infection and is a pan-genotypic nonstructural protein 5A (NS5A) inhibitor. | |||
T7387 | Ceftaroline fosamil | TAK-599,PPI0903 | Antibacterial , Antibiotic |
Ceftaroline fosamil (TAK-599) is a cephalosporin, with activity against Gram-positive pathogens. | |||
T1675 | Adefovir dipivoxil | Hepsera,GS 0840,Preveon | Others , HBV , Reverse Transcriptase |
Adefovir dipivoxil (GS 0840) is a dipivoxil formulation of adefovir, a nucleoside reverse transcriptase inhibitor analog of adenosine with activity against hepatitis B virus (HBV), herpes virus, and human immunodeficienc... | |||
T15781 | LP-935509 | Serine/threonin kinase , AAK1 (AP2 associated kinase 1) | |
LP-935509 is highly brain-penetrant and reverses fully established pain behavior following the SNL procedure. LP-935509 is also an effective inhibitor of BIKE (IC50=14 nM) and a modest inhibitor of GAK (IC50=320 nM). LP-... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T9599 | 3,4,5-Trimethoxybenzaldehyde | Anti-infection , Antibacterial | |
3,4,5-Trimethoxybenzaldehyde shows anti-Candida efficacy and inhibits adhesion and biofilms. | |||
T8716 | Physalin F | Apoptosis | |
Physalin F is a natural blocker of CaV2.3 (R-type) and CaV2.2 (N-type) voltage-gated calcium channels.It is a secosteroid with potent anti-inflammatory and immunomodulatory activities. Physalin F induces apoptosis of PBM... | |||
T9715 | Aplidine | SARS-CoV , DNA/RNA Synthesis | |
Aplidine possesses antiviral activity against SARS-CoV-2(IC90 = 0.88 nM). Aplidine is a potent anti-cancer agent by targeting eukaryotic translation elongation factor 1 Alpha 2(EEF1A2, Kd = 80 nM). | |||
T8205 | Norwogonin | 5,7,8-Trihydroxyflavone | Virus Protease |
Norwogonin (5,7,8-Trihydroxyflavone), isolated from Scutellaria baicalensis Georgi, possesses antiviral activity against Enterovirus 71 (IC50: 31.83 μg/ml). | |||
T1313 | Nitrofurantoin | Furadantine,Macrodantin,Furadonine | Antibacterial , Antibiotic |
Nitrofurantoin (Furadantine), an antibiotic, inhibits bacterial DNA, RNA, and cell wall protein synthesis. Activated by bacterial flavoproteins to intermediates that inactivate bacterial ribosomal proteins, Nitrofurantoi... | |||
T20712 | Conessine | Conessinum,Wrightine,Roquessine,Neriine,Konessin | Histamine Receptor |
Conessine (Conessinum), a steroidal alkaloid isolated from Holarrhena floribunda, interacts with the histamine H3 receptor and has anti-malarial activity. | |||
T8689 | Chloroquine | CQ | SARS-CoV , TLR , HIV Protease , Antibiotic , Parasite , Autophagy |
Chloroquine is a Toll-like receptor inhibitor that inhibits autophagy. Chloroquine has anti-malarial and anti-inflammatory activity and is widely used in the treatment of malaria and rheumatoid arthritis. Chloroquine als... | |||
TN2111 | Prunin | Naringenin 7-0-glucoside | Phosphatase , Anti-infection , Virus Protease |
Prunin (Naringenin 7-0-glucoside) possesses anti-diabetic, and anti-abacterial properties, it can inhibit protein tyrosine phosphatase 1B (PTP1B) and stimulate glucose uptake in insulin-resistant HepG2 cells; it also can... | |||
T1079 | Metronidazole | Flagyl,Metronidazol,Anagiardil | Apoptosis , NADPH , Hydrogenase , Antibacterial , Antibiotic , Parasite , Antifection |
Metronidazole (Metronidazol) is a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities. | |||
T3950 | Tridecanoic acid | n-Tridecoic Acid,n-Tridecanoic Acid,Tridecylic Acid | Others , Endogenous Metabolite , Antibacterial |
Tridecanoic acid (Tridecylic Acid) is a 13-carbon saturated fatty acid found in dairy products and also as a product of anaerobic biodegradation of n-hexadecane. It has been identified as a substrate of phospholipase A2. | |||
T1104 | Paromomycin Sulfate | Aminosidine sulfate,Paromomycin sulfate salt | Antibacterial , Antibiotic , Parasite |
Paromomycin binds specifically to the RNA oligonucleotide at the A site of bacterial 30S ribosomes, thereby causing misreading and premature termination of translation of mRNA and inhibition of protein synthesis followed... | |||
T1505 | Imipenem monohydrate | N-Formimidoyl thienamycin monohydrate,Imipenem | Antibacterial , Antibiotic |
Imipenem monohydrate (Imipenem) is a broad-spectrum, semi-synthetic beta-lactam carbapenem derived from thienamycin, produced by Streptomyces cattleya. | |||
T0956 | Avermectin B1 | Avermectin B1a-Avermectin B1b mixt.,Abamectin | Antibiotic , Parasite , Autophagy |
Avermectin B1 is served as anthelmintic and insecticide. | |||
TN3500 | Beta-Amyrone | β-Amyron | COX , AChR , PPAR , Antifection |
beta-Amyrone (β-Amyron) has antifungal activity against Chikungunya virus replication with an EC50 of 86 uM. beta-Amyrone has anti-inflammatory activity through inhibiting the expression of COX-2. beta-Amyrone exhibits a... | |||
T0974 | Novobiocin Sodium | Albamycinsodium,Cathomycin,Albamycin | Potassium Channel , DNA gyrase , Topoisomerase , Antibacterial , Antibiotic , ABC , Autophagy |
Novobiocin Sodium (Albamycinsodium) binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound derived from Streptomyces niveus. It has a chemical structure sim... | |||
T8261 | Ceftazidime Pentahydrate | Antibacterial , Antibiotic | |
Ceftazidime is a β-lactam antibacterial agent which has demonstrated a broad spectrum of activity against Gram-positive and Gram-negative aerobic bacteria. | |||
T0194 | Chloroquine phosphate | Chloroquine diphosphate,Aralen phosphate,Chingamin phosphate | SARS-CoV , TLR , HIV Protease , Antibiotic , Parasite , Autophagy |
Chloroquine phosphate (Aralen phosphate) is an aminoquinoline antimalarial and also is widely used as an autophagy inhibitor. Chloroquine also is an inhibitor of toll-like receptors (TLRs). | |||
T3S1852 | Cephaeline hydrochloride | Others , Virus Protease , Influenza Virus | |
Cephaeline hydrochloride, a phenolic alkaloid found in Indian Ipecac, effectively inhibits the infection of viruses ZIKV and EBOV. | |||
T4816 | 6-Hydroxynicotinic acid | 6-Hydroxypyridine-3-carboxylic acid,2-Hydroxy-5-pyridinecarboxylic acid | Others , Endogenous Metabolite |
6-Hydroxynicotinic acid (6-Hydroxypyridine-3-carboxylic acid) is exploited in the use of NMR spectroscopy or gas chromatography--mass spectrometry for the diagnosis of Pseudomonas aeruginosa in urinary tract infection. A... | |||
T3667 | Kalii Dehydrographolidi Succinas | Ddhads,Dehydroandrographolide Succinate Potasium Salt | Others |
Kalii Dehydrographolidi Succinas (Dehydroandrographolide Succinate Potasium Salt) is a natural compound with anti-virus infection activity. | |||
T2S0257 | Dehydroandrographolide succinate | Others , Influenza Virus | |
Dehydroandrographolide Succinate is a traditional Chinese medicine used in the treatment of pneumonia, respiratory tract infection. | |||
T0729 | Benzyl benzoate | Ascabiol,Novoscabin,Scabitox,Benzoic acid benzyl ester | Parasite |
Benzyl benzoate (Benzoic acid benzyl ester) is one of the older preparations used for the therapy of scabies. Scabies is a skin infection caused by the Sarcoptes scabiei. Its symptoms are red spots, severe itching (parti... | |||
T34295 | Resiniferatoxin | RTX,[3H]resiniferatoxin | IL Receptor |
Resiniferatoxin ([3H]resiniferatoxin) inhibits the production of Th1 cytokines, contributing to the defense against T. spiralis infection, and can be used in studies about the modulator of the immune response. | |||
T16165 | Myriocin | ISP-I,Thermozymocidin | HCV Protease , Antifungal |
Myriocin (Thermozymocidin), a metabolite derived from Myriococcum albomyces, is a serine-palmitoyltransferase (SPT) inhibitor with potential antitumour, anticancer, and antiparasitic activities.Myriocin inhibits tumour g... | |||
T38375 | Pseudane IX | 2-nonyl-4-hydroxyquinoline,2-nonyl-1H-quinolin-4-one,2-nonyl-4(1h)-quinolone | HCV Protease |
Pseudane IX (2-nonyl-1H-quinolin-4-one) reduces infection of Huh 7.5 cells by hepatitis C virus (HCV) with an IC50 of 1.4 μg/ml. | |||
TN1877 | Lonicerin | Apoptosis , Antibacterial | |
Lonicerin has antioxidant, anti-arthritic and antifungal activities, it can result in a combination therapy for the treatment of fungal arthritis due to C. albicans infection. | |||
T8257 | Maduramicin ammonium | Maduramicin,Maduramycin Ammonium | Apoptosis , Antibacterial , Antibiotic |
Maduramicin ammonium (Maduramycin Ammonium) is an anticoccidial agent for the the treatment of Eimeria spp., E. adenoeides, E. gallopavonis, and E. dispersa infection | |||
TN3207 | 7,3′,4′-Tri-O-methyleriodictyol | 7,3',4'-Tri-O-methyleriodictyol | Antioxidant , Antibiotic |
7,3′,4′-Tri-O-methyleriodictyol (7,3;,4;-Tri-O-methyleriodictyol) is an isolate from the methanolic extract of Pogostemon cablin that possesses antimicrobial, antioxidant, antitumor, and antiprotozoal activities and inhi... | |||
T3810 | Saikosaponin B2 | Others , HCV Protease | |
Saikosaponin B2 acts on HCV E2 and inhibits infection by several genotypic strains and prevents binding of serum-derived HCV onto hepatoma cells. Saikosaponin B2 (5 μM) induces differentiation of B16 melanoma cells, with... | |||
TN3048 | 4-Methoxycinnamaldehyde | p-Methoxycinnamaldehyde | RSV |
4-Methoxycinnamaldehyde (p-Methoxycinnamaldehyde) is an active ingredient of Agastache rugosa.4-Methoxycinnamaldehyde has cytoprotective activity against respiratory syncytial virus (RSV) in human laryngeal carcinoma cel... | |||
T3S0057 | Dihydrochelerythrine | 12,13-Dihydrochelerythrine | Antifungal |
1. Dihydrochelerythrine (12,13-Dihydrochelerythrine) is nontoxic up to 5μM concentration. 2. Dihydrochelerythrine has antifungal activity against pathogenic plant fungi. 3. Dihydrochelerythrine has potential application ... | |||
T1165 | Ethionamide | Bayer 5312,2-ethylthioisonicotinamide,Ethinamide | Dehydrogenase , CAT , Antibacterial , Antibiotic |
Ethionamide (2-ethylthioisonicotinamide) is a nicotinamide derivative, with antibacterial activity, used to treat tuberculosis. Although the exact mechanism of action of ethionamide is unknown, it may inhibit the synthes... | |||
T6S1885 | Benzoylmesaconine | Mesaconine 14-benzoate | Others |
Benzoylmesaconine (Mesaconine 14-benzoate) is the most abundant component of Wutou decoction, which is widely used in China because of its therapeutic effect on rheumatoid arthritis. Benzoylmesconine has analgesic activi... | |||
T6S0525 | Farrerol | ERK , p38 MAPK , Akt | |
1. Farrerol has antioxidative activity.2. Farrerol modulates TAP and BNBD5 gene expression in mammary gland, enhances bMEC defense against S. aureus infection and could be useful in protection against bovine mastitis. 3.... | |||
TN5263 | 1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one | Xanthohumol | Apoptosis , BCL , PARP , HCV Protease , IAP , Caspase , HIV Protease , NMDAR , p53 |
1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one (Xanthohumol) , prenylchacone flavonoid, is a natural product with multi-biofunctions purified from Hops Humulus lupulus,is e... | |||
T6S1572 | Sauchinone | ERK , p38 MAPK , NF-κB | |
1. Sauchinone is a useful adjunctive treatment for bacterial infection. 2. Sauchinone, an active lignan found in Saururus chinensis, to regulate the activation of HSCs, to prevent liver fibrosis, and to inhibit oxidative... | |||
T37753 | Aureusimine B | Cysteine Protease , Antibacterial | |
Aureusimine B, also known as phevalin, is a natural pyrazinone produced by certain fungi and by Staphylococcus spp., including S. aureus. Its synthesis appears to be initiated by a conserved nonribosomal peptide syntheta... | |||
TN1722 | Hamamelitannin | Antifection | |
Hamamelitannin has cytotoxic, and antibiofilm activities. It increases the susceptibility of S. aureus to antibiotic treatment in in vivo Caenorhabditis elegans and mouse mammary gland infection models. It also has a hig... | |||
T37876 | Fengycin | ||
Fengycin, a cyclic lipopeptide, functions as an agricultural fungicide by exhibiting an anti-fungal infection effect through damaging the target's cell membrane[1]. | |||
T11895 | Luteolin-7-rutinoside | Others | |
TN3809 | Dehydrojuncusol | HCV Protease | |
Dehydrojuncusol, a new inhibitor of hepatitis C virus RNA replication, it inhibits infection of different HCV genotypes by targeting the NS5A protein and is active against resistant HCV variants frequently found in patie... | |||
TN5079 | Sulochrin | HCV Protease , Antifection | |
Sulochrin shows antifungal and antibacterial activities, it can inhibit hepatitis C virus (HCV) infection in a dose-dependent manner without any apparent cytotoxicity up to 50 uM. Sulochrin has an inhibitory activity to ... | |||
T13199 | Triacsin C | WS 1228A,FR 900190 | Others |
Triacsin C (WS 1228A) from Streptomyces aureofaciens is a differential inhibitor of arachidonic acid coenzyme A synthetase and non-specific long-chain acyl-coenzyme A synthetase, with anti-atherosclerotic activity, inhib... | |||
TN1649 | Frangulin A | Others | |
Frangulin A protects Vitis vinifera leaves from Plasmopara viticola infection and inhibits the first stage of biotrophic hyphal development of P. Viticola. | |||
T38295 | Calpinactam | ||
Calpinactam is a fungal metabolite originally isolated from M. alpina that has antimycobacterial activity. It is active against M. smegmatis (MIC = 0.78 μg/ml) but not a panel of 13 other bacteria and fungi. Calpinactam ... | |||
TN4308 | Isolupalbigenin | Antifection | |
Isolupalbigenin shows promising cytotoxic effects toward HL-60 cells (IC50 4.3 ± 0.7 to 18.0 ± 1.7 uM), it also shows in vitro inhibitory activity toward human glyoxalase I. Isolupalbigenin shows two different antibacter... | |||
T75450 | P-orlandin | ||
P-orlandin, a fungal metabolite, effectively impedes Plasmodium falciparum infection in mosquitoes by preventing FREP1 from binding to gametocytes or ookinetes [1]. | |||
T79934 | Clavirolide L | ||
Clavirolide L (Compound 3), a dolabellane-type diterpenoid isolated from Clavularia viridis, demonstrates significant inhibition against HIV-1 without inhibiting the RT enzyme, making it a valuable agent for HIV infectio... | |||
TN1632 | Euparin | Antifection | |
Euparin exhibits a moderate antioxidant activity, it also exhibits antifungal activity against Trichophyton mentagrophytes. Euparin has antiviral activity, it exerts its effect during the early events of the replication ... | |||
T35751 | Violacein | ||
Violacein is a bacterial metabolite originally isolated from C. violaceum that has antibacterial and antiprotozoal activities.[1] [2] It is produced by C. violaceum as a purple pigment in response to N-hexanoyl homoserin... | |||
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カタログ番号 | 製品名 | Species | Expression System |
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TMPK-00047 | IFN gamma Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Interferon-gamma (IFN gamma) is a cytokine that plays physiologically important roles in promoting innate and adaptive immune responses. The absence of IFN gamma production or cellular responsiveness in humans and experi... | |||
TMPY-02929 | ENTPD2 Protein, Human, Recombinant (aa 29-460, His) | Human | Baculovirus Insect Cells |
NTPDase 2, also known as ENTPD2, belongs to the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). Members of E-NTPDase family are nucleotidases able to hydrolyze 5′-nucleoside tri- and/or diphosphates; ... | |||
TMPY-02219 | Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His) | H1N1 | E. coli |
The NS1 Influenza protein is created by the internal protein-encoding, linear negative-sense, single-stranded RNA, NS gene segment and which also codes for the nuclear export protein or NEP, formerly referred to as the N... | |||
TMPY-06802 | HSV 2 (strain 333) Glycoprotein D/gD Protein (His) | HSV2 | HEK293 Cells |
Herpes simplex viruses (human herpesviruses types 1 and 2) commonly cause recurrent infection affecting the skin, mouth, lips, eyes, and genitals. Herpes simplex virus type 2 (HSV-2) infection is responsible for signific... | |||
TMPK-01231 | CLEC2D Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 Cells |
C-type lectin domain family 2, member D (CLEC2D) is implicated in the immune response. Pre-eclampsia and HIV infection have opposing immune responses. The contrasting expression of CLEC2D in HIV infection and pre-eclamps... | |||
TMPH-01632 | MRC1 Protein, Human, Recombinant (His) | Human | E. coli |
Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains.; (Microbial infection) Acts as phagocytic receptor for bacteria, fungi and other pathogens.; (Microbia... | |||
TMPH-00696 | OmpC Protein, E. coli, Recombinant | E. coli | E. coli |
Forms pores that allow passive diffusion of small molecules across the outer membrane.; (Microbial infection) Supports colicin E5 entry in the absence of its major receptor OmpF.; (Microbial infection) A mixed OmpC-OmpF ... | |||
TMPK-01230 | CLEC2D Protein, Human, Recombinant (hFc & Avi) | Human | HEK293 Cells |
C-type lectin domain family 2, member D (CLEC2D) is implicated in the immune response. Pre-eclampsia and HIV infection have opposing immune responses. The contrasting expression of CLEC2D in HIV infection and pre-eclamps... | |||
TMPH-01672 | Human metapneumovirus (strain CAN97-83) Matrix protein (His & Myc) | HMPV | E. coli |
Plays a crucial role in virus assembly into filaments and budding. Early in infection, localizes in the nucleus where it may inhibit host cell transcription. Later in infection, traffics to the cytoplasm through the acti... | |||
TMPH-00697 | OmpF Protein, E. coli, Recombinant (His & Myc) | E. coli | E. coli |
Forms pores that allow passive diffusion of small molecules across the outer membrane.; (Microbial infection) It is also a receptor for the bacteriophage T2. Is the major receptor for colicin E5.; (Microbial infection) A... | |||
TMPY-04144 | Kremen-1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
KREMEN1 (Kringle Containing Transmembrane Protein 1) is a Protein Coding gene. This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (... | |||
TMPH-00695 | OmpC Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Forms pores that allow passive diffusion of small molecules across the outer membrane.; (Microbial infection) Supports colicin E5 entry in the absence of its major receptor OmpF.; (Microbial infection) A mixed OmpC-OmpF ... | |||
TMPH-01283 | EEF1A1 Protein, Human, Recombinant (His) | Human | E. coli |
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays a role in the positive regulation of IFNG transcription in T-helper 1 cells as part of an IF... | |||
TMPH-01284 | EEF1A1 Protein, Human, Recombinant | Human | E. coli |
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays a role in the positive regulation of IFNG transcription in T-helper 1 cells as part of an IF... | |||
TMPH-01673 | Human metapneumovirus (strain CAN97-83) Matrix protein (His) | HMPV | P. pastoris (Yeast) |
Plays a crucial role in virus assembly into filaments and budding. Early in infection, localizes in the nucleus where it may inhibit host cell transcription. Later in infection, traffics to the cytoplasm through the acti... | |||
TMPH-01600 | Lactoperoxidase/LPO Protein, Human, Recombinant (His & Myc) | Human | HEK293 Cells |
Antimicrobial agent which utilizes hydrogen peroxide and thiocyanate (SCN) to generate the antimicrobial substance hypothiocyanous acid (HOSCN). May contribute to airway host defense against infection. | |||
TMPH-01575 | KRT10 Protein, Human, Recombinant (His) | Human | E. coli |
Plays a role in the establishment of the epidermal barrier on plantar skin.; (Microbial infection) Acts as a mediator of S.aureus adherence to desquamated nasal epithelial cells via clfB, and hence may play a role in nas... | |||
TMPH-00152 | IBV (strain UK/167/84) Spike glycoprotein (His) | IBV | E. coli |
S1 attaches the virion to the cell membrane by interacting with cell receptors, initiating the infection. IBV (strain UK/167/84) Spike glycoprotein (His) is expressed in E. coli expression system with C-6xHis tag. The pr... | |||
TMPH-00033 | ASFV (strain Ba71V) p30 Protein (His) | ASFV | E. coli |
Modifies the subcellular distribution of heterogeneous nuclear ribonucleoprotein K (HNRNPK) and may contribute to modulate HNRNPK functions related to processing and export of mRNAs during ASFV infection. | |||
TMPH-02239 | TMPRSS4 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Plasma membrane-anchored serine protease that directly induces processing of pro-uPA/PLAU into the active form through proteolytic activity. Seems to be capable of activating ENaC.; (Microbial infection) In gut epithelia... | |||
TMPK-01267 | TREM-1 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
TREM1 (Triggering Receptor Expressed on Myeloid Cells 1) is a pro-inflammatory receptor expressed by phagocytes, which can also be released as a soluble molecule (sTREM1). The roles of TREM1 and sTREM1 in liver infection... | |||
TMPH-00133 | AcMNPV Major capsid Protein (His & Myc) | AcMNPV | E. coli |
Most abundant structural protein of the nucleocapsid produced during the infection cycle. The monomers are arranged in stacked rings around the nucleoprotein core. AcMNPV Major capsid Protein (His & Myc) is expressed in ... | |||
TMPH-00151 | IBV (strain UK/142/86) Spike glycoprotein (His) | IBV | E. coli |
S1 attaches the virion to the cell membrane by interacting with cell receptors, initiating the infection. IBV (strain UK/142/86) Spike glycoprotein (His) is expressed in E. coli expression system with C-6xHis tag. The pr... | |||
TMPK-00550 | CD55/DAF Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Decay Accelerating Factor (or CD55) is a major regulator of the alternative and classical pathways of complement activation and is expressed on all serum-exposed cells. It is commonly hijacked by invading pathogens, incl... | |||
TMPH-00761 | Cutinase Protein, Fusarium solani subsp. Cucurbitae, Recombinant | Neocosmosporum cucurbitae | E. coli |
Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle. Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of the fungal infe... | |||
TMPY-02516 | Interferon alpha 10/IFNA10 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Interferon alpha-10 (IFNA10) is a member of the interferon family. Interferons belong to the group of the regulatory glycoproteins, of low molecular mass. They are the products of infected cell-genome, but not virus, as ... | |||
TMPH-00424 | Cutinase Protein, Colletotrichum capsici, Recombinant (His & SUMO) | Colletotrichum capsici | E. coli |
Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle. Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of the fungal infe... | |||
TMPK-01467 | HLA-A*02:01&B2M&HPV 16 E6 (KLPQLCTEL) Monomer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
Human papillomavirus (HPV) 16 infection is a necessary condition for the pathogenesis and development of cervical cancer. The E6 protein is expressed by the HPV16 E6 gene and promotes malignant phenotype transformation, ... | |||
TMPK-01466 | HLA-A*02:01&B2M&HPV 16 E6 (KLPQLCTEL) Tetramer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
Human papillomavirus (HPV) 16 infection is a necessary condition for the pathogenesis and development of cervical cancer. The E6 protein is expressed by the HPV16 E6 gene and promotes malignant phenotype transformation, ... | |||
TMPH-03021 | PstP Protein, Mycobacterium tuberculosis, Recombinant (His) | Mycobacterium tuberculosis | E. coli |
Plays an important role in regulating cell division and growth by reversible phosphorylation signaling. May play important roles in regulating cellular metabolism and signaling pathways, which could mediate the growth an... | |||
TMPH-00549 | Epstein-Barr virus (strain GD1) BZLF1 Protein (His & Myc) | EBV | E. coli |
Plays a key role in the switch from latent infection to lytic cycle producing new virions. Acts as a transcription factor, inducing early lytic cycle genes, and as a origin binding protein for genome replication. BZLF1 a... | |||
TMPH-00548 | Epstein-Barr virus (strain B95-8) BZLF1 Protein (His & SUMO) | EBV | E. coli |
Plays a key role in the switch from latent infection to lytic cycle producing new virions. Acts as a transcription factor, inducing early lytic cycle genes, and as a origin binding protein for genome replication. BZLF1 a... | |||
TMPY-04904 | Zika virus (ZIKV) (strain Zika SPH2015) M/Membrane protein (Fc) | ZIKV | HEK293 Cells |
Zika virus (ZIKV) infection causes microcephaly and has been linked to other brain abnormalities. ZIKV has a more selective and larger impact on the expression of genes involved in DNA replication and repair. P53 inhibit... | |||
TMPH-01550 | Interferon kappa/IFNK Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
May play a role in the regulation of immune cell function. Cytokine that imparts cellular protection against viral infection in a species-specific manner. Activates the interferon-stimulated response element signaling pa... | |||
TMPK-00705 | MASP2 Protein, Human, Recombinant (His) | Human | E. coli |
The pathogenesis of severe acute respiratory disease syndrome (SARS) is not fully understood. One case-control study has reported an association between susceptibility to SARS and mannan-binding lectin (MBL) in China. As... | |||
TMPH-01269 | SMURF2 Protein, Human, Recombinant (His) | Human | E. coli |
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Interacts with SMAD7 to trigger SMA... | |||
TMPH-02989 | ESAT-6 Protein, Mycobacterium bovis, Recombinant (His & Myc) | Mycobacterium bovis | E. coli |
A secreted protein. Acts as a strong host T-cell antigen. Plays a number of roles in modulating the host's immune response to infection as well as being responsible for bacterial escape into the host cytoplasm. ESAT-6 Pr... | |||
TMPH-01104 | Claudin-9 Protein-VLP, Human, Recombinant (His) | Human | HEK293 Cells |
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.; (Microbial infection) Acts as a receptor for hepatitis C virus (HCV) entry into ... | |||
TMPH-00760 | Cutinase Protein, Fusarium solani subsp. Cucurbitae, Recombinant (His) | Neocosmosporum cucurbitae | P. pastoris (Yeast) |
Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle. Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of the fungal infe... | |||
TMPH-01457 | Human herpesvirus 6B (HHV-6 variant B) (strain Z29) mRNA export factor ICP27 homolog (His & Myc) | HHV-6B | E. coli |
Immediate early (EI) protein that plays many roles during productive infection including regulation of viral gene expression and nuclear export of intronless viral RNAs. Human herpesvirus 6B (HHV-6 variant B) (strain Z29... | |||
TMPK-00896 | CCR8 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and ... | |||
TMPK-01316 | CCR8 Protein, Cynomolgus, Recombinant (mFc) | Cynomolgus | HEK293 Cells |
CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and ... | |||
TMPK-01412 | HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
HLA-B*15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B*15:01 we... | |||
TMPH-01291 | ERVK-7 Protein, Human, Recombinant (His) | Human | E. coli |
Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution.; SU mediates re... | |||
TMPK-01416 | HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi), Biotinylated | Human | HEK293 Cells |
HLA-B*15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B*15:01 we... | |||
TMPK-00255 | CD209/DC-SIGN Protein, Human, Recombinant (His) | Human | HEK293 Cells |
C-type lectin CD209/DC-SIGN and CD209L/L-SIGN proteins are distinct cell adhesion and pathogen recognition receptors that mediate cellular interactions and recognize a wide range of pathogens, including viruses such as S... | |||
TMPH-03022 | PstP Protein, Mycobacterium tuberculosis, Recombinant | Mycobacterium tuberculosis | E. coli |
Plays an important role in regulating cell division and growth by reversible phosphorylation signaling. May play important roles in regulating cellular metabolism and signaling pathways, which could mediate the growth an... | |||
TMPK-00308 | Nectin-4 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Nectin-4 seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry in... | |||
TMPK-00135 | ULBP-1 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Cell surface proteins major histocompatibility complex (MHC) class I-related chain A (MICA) and UL16-binding proteins (ULBP) 1, 2, and 3 are up-regulated upon infection or tumor transformation and can activate human natu... | |||
TMPK-00134 | ULBP-1 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Cell surface proteins major histocompatibility complex (MHC) class I-related chain A (MICA) and UL16-binding proteins (ULBP) 1, 2, and 3 are up-regulated upon infection or tumor transformation and can activate human natu... | |||
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カタログ番号 | 製品名 | ||
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L1800 | Anti-Infection Compound Library | 2938 compounds | |
A unique collection of 2938 anti-infective compounds including anti-bacterial, anti-fungi, anti-Human Cytomegalovirus (HCMV), anti-HIV, anti-SARS, anti-influenza, etc; | |||
L3400 | Clinical Compound Library | 3404 compounds | |
A unique collection of 3404 compounds in clinical trial phases for high throughput screening (HTS) and high content screening (HCS); | |||
L9700 | Endoplasmic Reticulum Stress Compound Library | 193 compounds | |
A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS); | |||
L9420 | Exosome Compound Library | 76 compounds | |
76 exosome-related compounds that can be used for high-throughput and high-content screening. | |||
L2910 | Antioxidant Compound Library | 1314 compounds | |
Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species (ROS) and a biological system's ability to readily detoxify the reactive intermediates or repair the resulting damage. ... | |||
L9820 | Beta-Lactam Compound Library | 97 compounds | |
A unique collection of 97 beta-lactam compounds, can be used in HTS and HCS; | |||
L1720 | Nucleotide Compound Library | 334 compounds | |
A unique collection of 334 nucleoside and nucleotide analogues, can be used for research and development of anti-viral, anti-tumor, anti-fungal, and anti-depressive drugs; | |||
L6610 | Anti-infective Natural Product Library | 1060 compounds | |
A unique collection of 1060 species of natural products with anti-infective activity for high throughput screening (HTS) and high content screening (HCS); | |||
L7600 | Chemokine Inhibitor Library | 59 compounds | |
A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening; |