| TN2151 |
Rhamnocitrin
|
|
Others
|
|
Rhamnocitrin can enhance the immune function, improve the formation of spleen cells of mice serum hemolysin of chicken red blood cell immune. |
| TN6490 |
Regaloside C
|
|
Others
|
|
Regaloside C is a glycerol glucoside isolated from Lilium genus with anti-inflammatory properties. |
| TN2082 |
Pinostrobin
|
|
Beta Amyloid
,
IL Receptor
,
Serine/threonin kinase
,
TNF
|
|
Pinostrobin, a potent flavonoid inducer, exerts a neuroprotective effect against Aα²(25-35)-induced neurotoxicity in PC12 cells, at least in part, via inhibiting oxidative damage and calcium overload, as well as suppress... |
| T6S1369 |
Vitexin
|
Apigenin-8-C-glucoside |
Antioxidant
|
|
1. Vitexin has antinociceptive and antispasmodic activities. 2. Vitexin exhibits a prominent first-pass effect. 3. Vitexin has antioxidant, antimyeloperoxidase, and α-glucosidase inhibitory activities. 4. Vitexin can eit... |
| T3773 |
Oxypaeoniflorin
|
Oxypaeoniflora |
Others
|
|
Oxypaeoniflorin (Oxypaeoniflora) is a natural product derived from Radix Paeoniae Rubra and Radix Paeoniae Alba. |
| T2982 |
Xanthone
|
Genicide,Xanthenone,Benzophenone oxide |
Apoptosis
,
Others
,
Influenza Virus
,
Antibacterial
,
Antifungal
|
|
Xanthone (Xanthenone) is currently used as ovicide for codling moth eggs and as a larvicide. |
| T2S1200 |
Sinapine
|
|
Antioxidant
,
P-gp
,
AChE
|
|
1. Sinapine, an alkaloid from seeds of the cruciferous species, can be used as an effective natural compound for chemo-resistance. 2. Sinapine has antioxidant and radio-protective activities. |
| T7792 |
Hispidin
|
|
Endogenous Metabolite
,
PKC
|
|
Hispidin is a polyphenol originally, including antioxidant, anti-inflammatory, and cytoprotective properties |
| T3392 |
Sinapine thiocyanate
|
|
P-gp
,
AChE
|
|
Sinapine Thiocyanate, is a derivative of Sinapine (S486605), an alkaloidal amine found in black mustard seeds. It is the choline ester of Sinapic Acid (S486800). It is also a phenolic-chloine conjugates, acting as anti-o... |
| T4S0094 |
Hydroxygenkwanin
|
Luteolin 7-methylether,7-O-Methylluteolin |
Antioxidant
|
|
1. Hydroxygenkwanin (Luteolin 7-methylether) possesses significant the antioxidative activity . 2. Hydroxygenkwanin has cytotoxicity, may be an effective natural product to treat glioma, and the combination of Apigenin a... |
| T2895 |
Lupeol
|
Fagarasterol,Monogynol B,Clerodol,(3β,13ξ)-Lup-20(29)-en-3-ol,Farganasterol |
Apoptosis
,
Androgen Receptor
,
Akt
|
|
Lupeol (Monogynol B) is a novel androgen receptor inhibitor with anti-inflammatory and antioxidant activity. |
| T7026 |
KukoaMine B
|
|
Antioxidant
|
|
Kukoamine B, as a constituent of Lycii Cortex, exhibits anti-acute inflammatory, anti-oxidant, and anti-diabetic characteristics. |
| T2807 |
Caffeic Acid
|
|
Lipoxygenase
,
Endogenous Metabolite
,
TRP/TRPV Channel
|
|
Caffeic Acid is an orally bioavailable, hydroxycinnamic acid derivative and polyphenol, with potential anti-oxidant, anti-inflammatory, and antineoplastic activities. |
| T3799 |
Isorhamnetin-3-O-neohespeidoside
|
Isorhamnetin 3-O-neohesperidin,Isorhamnetin 3-O-neohesperoside,Calendoflavoside |
Antioxidant
|
|
Isorhamnetin-3-O-neohespeidoside (Calendoflavoside) is a flavonol glycoside extract used as an anti-oxidant. |
| T3830 |
20(R)-Ginsenoside Rg2
|
20R-Ginsenoside Rg2 |
IL Receptor
|
|
20(R)-Ginsenoside Rg2 (20R-Ginsenoside Rg2) is a compound with anti-oxidant and anti-apoptosis. |
| T4088 |
Thymoquinone
|
NSC 2228,Thymoquinon |
BCL
|
|
Thymoquinone (NSC 2228) is a compound be found in herbs and spices with anti-inflammatory and anti-oxidant effects. |
| T3784 |
Lithospermoside
|
Griffonin |
Others
|
|
Lithospermoside (Griffonin) has anti-oxidant, anti-tumor promoting activities. |
| T4955 |
Saponaretin
|
Isovitexin,Apigenin-6-C-glucoside |
Apoptosis
,
Antioxidant
|
|
saponaretin, an active component of many traditional Chinese medicines, shows various activities, such as anti-oxidant, anti-inflammatory, anti-alzheimer disease (AD) effects and so on. |
| TJS0338 |
4-Methylesculetin
|
4-Methyl-6,7-dihydroxycoumarin,Methylesculetin |
Antioxidant
,
Glutathione Peroxidase
|
|
4-Methylesculetin (Methylesculetin) is one of the coumarin derivatives with great anti-oxidant and anti-inflammatory activities. |
| T5S0092 |
Epigoitrin
|
BA-51-090278,Goitrine,D-Goitrin,Goitrin |
Antiviral
,
Influenza Virus
|
|
1. Epigoitrin (Goitrin) has anti-virus activity. 2. Epigoitrin has anti-oxidant activity. 3. Epigoitrin has anti-inflammation activity. |
| T4587 |
Mirificin
|
BCP10902,Puerarin Apioside |
Tyrosinase
|
|
Mirificin (BCP10902) is an active ingredient in Tongmai formula (TMF) which is a well-known Chinese medicinal preparation. Anti-oxidant. |
| T2781 |
Sanguinarine
|
Sanguinarin,Pseudochelerythrine |
Apoptosis
,
Antioxidant
,
Autophagy
|
|
Sanguinarine (Pseudochelerythrine) is a specific inhibitor of Rac1b with anti-microbial, anti-oxidant and anti-inflammatory properties. |
| T2901 |
Daidzin
|
NPI-031D,Daidzein 7-O-glucoside,Daidzoside,Daidzein 7-glucoside |
Dehydrogenase
,
Reverse Transcriptase
,
Mitochondrial Metabolism
|
|
Daidzin (Daidzoside) is an isoflavone isolated from soya bean with anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities. |
| T7600 |
Fucoxanthin
|
all-trans-Fucoxanthin |
Others
|
|
Fucoxanthin (all-trans-Fucoxanthin) is a carotenoid that occurs naturally in certain algae. It is found as an accessory pigment in the chloroplasts of brown algae and most other heterokonts, giving them a brown or olive-... |
| T5712 |
Zerumbone
|
|
Antioxidant
,
HSV
|
|
Zerumbone is a natural monocyclic sesquiterpene first isolated from rhizomes of the wild ginger Z. zerumbet.It has also been shown to have anti-oxidant and anti-inflammatory activities, contributing to immunomodulatory a... |
| T5S1607 |
Morusin
|
Mulberrochromene |
NF-κB
,
Antibacterial
,
STAT
|
|
1. Morusin (Mulberrochromene) possesses antitumor effects of cell lines including HT-29, A549, MCF-7, and MDA-MB-231, through suppressing STAT3 and NFκB attenuation mediated apoptosis induction. 2. Morusin possesses anti... |
| T5720 |
Boldine
|
1,10-Dimethoxy-2,9-dihydroxyaporphine,ex Peumus boldus |
RANKL/RANK
|
|
Boldine (1,10-Dimethoxy-2,9-dihydroxyaporphine) is a natual product .Boldine displays anti-cancer, cytoprotective , anti-oxidant and anti-inflammatory activities. |
| T2902 |
Costunolide
|
Costus lactone,NSC 106404,Costunolid,(+)-Costunolide |
Apoptosis
,
Endogenous Metabolite
,
Telomerase
|
|
Costunolide (Costus lactone) has anti-inflammatory and anti-oxidant properties and mediates apoptosis. |
| T3744 |
Veratric acid
|
Veratrumenoic acid,3,4-Dimethoxybenzoic acid |
Reactive Oxygen Species
,
COX
|
|
Veratric acid (3,4-Dimethoxybenzoic acid) is a simple benzoic acid derived from plants and fruits with anti-oxidant, anti-inflammation and blood pressure-lowering effects. |
| T4S2164 |
Narirutin
|
Naringenin-7-O-rutinoside,Isonaringin |
Others
,
Antibacterial
|
|
1. Narirutin (Naringenin-7-O-rutinoside) has antiproliferative property. 2. Narirutin has anti-oxidant property. 3. Narirutin has anti-allergic and anti-inflammatory properties , can reduce airway inflammation in ovalbum... |
| T0539 |
Dihydrocaffeic acid
|
Hydrocaffeic acid |
Antioxidant
,
p38 MAPK
,
Endogenous Metabolite
|
|
Dihydrocaffeic acid (Hydrocaffeic acid), a metabolite of chlorogenic acid, is a well-known anti-oxidant component, has anti-oxidative, anti-Alzheimer's, neuroprotective, arousal, and lipid-lowering effects. |
| T7174 |
Urolithin A
|
|
Apoptosis
,
Reactive Oxygen Species
,
DNA/RNA Synthesis
,
Endogenous Metabolite
,
Autophagy
,
Drug Metabolite
|
|
Urolithin A is a secondary metabolite of ellagic acid, a polyphenolic antioxidant, that has antiproliferative, anti-inflammatory, and anti-oxidant properties. |
| T3376 |
Cynaroside
|
Luteoloside,Luteolin 7-β-D-Glucopyranoside,Luteolin 7-O-Glucoside,Luteolin 7-O-β-D-glucoside,Luteolin 7-glucoside |
Others
,
Influenza Virus
,
DNA/RNA Synthesis
|
|
Cynaroside (Luteolin 7-O-Glucoside) is a flavone, a flavonoid-like chemical compound. It has an anti-oxidant effect, inhibiting lipid and protein oxidation. |
| T14008 |
2,2,5,7,8-Pentamethyl-6-Chromanol
|
PMC |
Androgen Receptor
|
|
2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) is the anti-oxidant moiety of vitamin E (α-tocopherol), which has potent androgen receptor (AR) signaling modulation and anti-cancer activity against prostate cancer cell lines. |
| T3665 |
Tectoridin
|
Shekanin |
Estrogen Receptor/ERR
,
Reductase
|
|
Tectoridin (Shekanin) possesses an estrogenic and thyroid hormone-like agent by activating estrogen and thyroid hormone receptors. Tectoridin has anti-oxidant, anti-inflammatory and hypoglycemic activities; Tectoridin an... |
| TN1557 |
Decursinol angelate
|
|
ERK
,
VEGFR
,
PKC
,
JNK
|
|
Decursinol angelate has anti-tumor, anti-inflammatory, anti-oxidant, and hepatoprotective activities, it inhibits VEGF-induced angiogenesis via suppression of the VEGFR-2-signaling pathway; it also suppresses invasion an... |
| T2860 |
Vanillyl Alcohol
|
4-Hydroxy-3-methoxybenzenemethanol,3-Methoxy-4-hydroxybenzyl alcohol,4-Hydroxy-3-methoxybenzyl alcohol,Vanillin alcohol,Vanillic alcohol |
Apoptosis
,
Others
|
|
Vanillyl Alcohol (3-Methoxy-4-hydroxybenzyl alcohol) possesses anti-angiogenic, anticonvulsive, anti-inflammatory, anti-oxidant, neuroprotective, and anti-nociceptive activities. Vanillyl alcohol can effectively inhibit ... |
| T2851 |
Daphnetin
|
7,8-Dihydroxycoumarin,Daphnetol |
EGFR
,
PKA
,
PKC
,
Parasite
,
Autophagy
|
|
Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM), and PKC (IC50: 25.01 μM), also exhibit anti-oxidant and anti-... |
| TN1410 |
Asperulosidic acid
|
ASPA |
ERK
,
NF-κB
|
|
Asperulosidic acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities. ASPA is related to the inhibition of inflammatory cytokines (TNF-α, IL-6) and mediators via suppression of the NF-κB and mitogen-a... |
| TN1816 |
Kadsurin
|
|
Antioxidant
|
|
Kadsurin has anti-oxidant activity, it induces enzymes capable of scavenging oxygen radical species in the liver. Kadsurin may be valuable antitumor promoters or chemopreventors. |
| T4S1943 |
Kirenol
|
Kirel |
Wnt/beta-catenin
|
|
1. Kirenol (Kirel) has anti-oxidant, anti-inflammatory, anti-allergic, and anti-arthritic activities. 2. Kirenol is effective against gram-positive bacteria. 3. Kirenol possesses antitumor action on human chronic myeloid... |
| T2S0731 |
Trilobatin
|
P-Phlorizin |
Amylase
|
|
Trilobatin (P-Phlorizin) has anti-oxidant effect, can increase superoxide dismutase (SOD) activity.Trilobatin has anti-inflammatory effect, it potentially inhibits the lipopolysaccharide (LPS)-induced inflammatory respon... |
| T1633 |
β-Carotene
|
Carotaben,Beta-Carotene,Provitamin A |
Apoptosis
,
ROS
,
Endogenous Metabolite
|
|
β-Carotene (Provitamin A) is a naturally-occurring retinol (vitamin A) precursor obtained from certain fruits and vegetables with potential antineoplastic and chemopreventive activities. As an anti-oxidant, beta carotene... |
| TN2244 |
Sulfuretin
|
|
NF-κB
,
Autophagy
|
|
Sulfuretin is a potent anti-oxidant, has protective effect against t-BHP-induced oxidative damage in human liver-derived HepG2 cells is attributable to its ability to scavenge ROS and up-regulate the activity of HO-1 thr... |
| T6S1027 |
Tussilagone
|
|
Others
|
|
1. Tussilagone inhibits dendritic cell function through the induction of heme oxygenase-1. 2. Tussilagone has anti-cancer activity, might be a potential chemotherapeutic agent for the prevention and treatment of human co... |
| T3138 |
Astaxanthin
|
β-Carotene-4,4'-dione,Ovoester,AstaXin,AstaREAL,trans-Astaxanthin |
Reactive Oxygen Species
,
PPAR
|
|
Astaxanthin (trans-Astaxanthin) is a keto-carotenoid in the terpenes class of chemical compounds. It is classified as a xanthophyll but it is a carotenoid with no vitamin A activity. It is present in most red-colored aqu... |
| TN1711 |
Gossypetin
|
|
Antioxidant
,
p38 MAPK
,
MAPK
,
Antibacterial
|
|
Gossypetin, a hexahydroxylated flavonoid extractable from Rhodiola rosea Linn. is a potent MKK3 and MKK6 inhibitor that strongly attenuates the MKK3/6-p38 signaling pathway.Gossypetin exhibits antimutagenic, antiatherosc... |
| TN1042 |
Chebulic acid
|
|
Others
|
|
Chebulic acid, a phenolcarboxylic acid compound isolated from Terminalia chebula, has potent anti-oxidant activity,which breaks the cross-links of proteins induced by advanced glycation end-products (AGEs) and inhibits t... |
| T6S2099 |
Geraniin
|
|
Antioxidant
,
TNF
|
|
1. Geraniin has a protective effect against OVX-induced rat osteoporosis. 2. Geraniin has cytotoxic activity towards cancer cells in vitro and in vivo. 3. Geraniin exerts inhibitory effects on osteoclast differentiation ... |
| T26290 |
Tremetone
|
NSC-247531,NSC247531,NSC 247531 |
|
|
Tremetone is a potent anti-inflammatory and anti-oxidant agent. |
