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ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T22012	7BIO		FLT , DYRK , Aurora Kinase
	7-bromoindirubin-3'-oxime (7BIO) is a caspase independent nonapoptotic cell death inducer. 7BIO is an inhibitor of FLT3, DYRK1A, DYRK2, Aurora B and Aurora C kinases.		FLT , DYRK , Aurora Kinase
T9125	Tolebrutinib	PRN2246,SAR442168	BTK
	Tolebrutinib (PRN2246) is a potent, selective, orally active and brain-penetrant Bruton tyrosine kinase (BTK) inhibitor(IC50s of 0.4 and 0.7 nM in Ramos B cells and in HMC microglia cells, respectively). It exhibits effi...		BTK
T2498	Adjudin	AF-2364	Chloride channel , Mitochondrial Metabolism
	Adjudin (AF-2364) is a small molecule compound known to possess antispermatogenic function, attenuates microglia activation by suppression of the NF-κB pathway.		Chloride channel , Mitochondrial Metabolism
T4450	GIBH-130		IL Receptor , TNF , Interleukin
	GIBH-130 markedly inhibits the IL-1β secretion by activated microglia (IC50: 3.4 nM). GIBH-130 is an effective inhibitor of neuroinflammation.		IL Receptor , TNF , Interleukin
T15622	JNJ-54175446	JNJ-5446	P2X Receptor
	JNJ-54175446 (JNJ-5446) is a CNS-permeable and selective P2X7 receptor antagonist that attenuates the release of IL-1β/IL-18 from microglia, and may be used in the study of depression.		P2X Receptor
T33535	MW01-2-151SRM	MW 151,MW-151,MW012151SRM,MW151,MW01 2 151SRM	Others
	MW01-2-151SRM is a novel small molecule inhibitor of microglia activation that crosses the blood-brain barrier, has anti-neuroinflammatory effects, attenuates the up-regulation of glial cytokines in models of neuroinflam...		Others
T13036L	Sulfosuccinimidyl oleate sodium	Sulfo-N-succinimidyl oleate sodium	Others
	Sulfosuccinimidyl oleate sodium (Sulfo-N-succinimidyl oleate sodium) is a long-chain fatty acid that inhibits the transport of fatty acids to cells. Sulfosuccinimidyl oleate sodium is an effective, irreversible inhibitor...		Others
T24161	IMM-H004	IMMH 004,IMMH-004,IMMH004
	IMM-H004 is an effective inhibitor of BV2 microglia activation.
T71863	LDDN-0003499
	LDDN-0003499 is a novel Src family tyrosine kinase inhibitor with anti-inflammatory effects in response to Aß stimulation of microglia.
T15463	(Rac)-HAMI 3379	HAMI 3379	Others
	HAMI 3379 is a potent and selective antagonist of the Cysteinyl leukotriene (CysLT2) receptor. HAMI 3379 has a protective effect on acute and subacute ischemic brain injury. It also attenuates microglia-related inflammat...		Others
T79590	Anti-neuroinflammation agent 1		NOD-like Receptor (NLR)
	Anti-neuroinflammation Agent 1 effectively modulates BV2 microglia cell polarization, shifting from an M1 to an M2 phenotype [1].		NOD-like Receptor (NLR)
T37390	NS 6740
	High affinity α7 nAChR partial agonist (Ki = 1.1 nM in rat; Emax < 10% of the response to ACh in rat and human). Inhibits ACh (IC50 = 2.7 nM) at α7 nAChR. Reduces LPS-induced TNF-α release from microglia enriched cultu...
T40849	C20 Ceramide	N-Arachidoyl-D-sphingosine	Endogenous Metabolite
	C20 Ceramide is a 20:0 ceramide found in the brain that crosses the blood-brain barrier to activate microglia and induce depressive-like behavior.		Endogenous Metabolite
T63364	Nrf2 activator-5
	Nrf2 activator-5 is a potent activator of Nrf2 that attenuates H2O2-induced oxidative stress and LPS-stimulated inflammation in BV-2 microglia, exhibiting antioxidant and anti-inflammatory activity.
T80422	Phoenixin-14	PNX-14	GNRH Receptor
	Phoenixin-14 (PNX-14), an active endogenous isoform, induces an anxiolytic effect by activating the AHA GnRH system in mice and protects against ischemia/reperfusion-induced cytotoxicity in microglia [1] [2].		GNRH Receptor
T64205	HAMI 3379
	HAMI 3379 is a potent and selective CysLT2 receptor antagonist. HAMI 3379 exhibits protective effects against acute and subacute ischaemic brain injury and reduces microglia-associated inflammation.
T61709	AMS-17
	AMS-17 is a potent NLRP3 inhibitor, which effectively suppresses microglia activation both in vitro and in vivo. Additionally, AMS-17 exhibits inhibitory effects on various cytokines, such as caspase-1, TNF-α, IL-1β, and...
T83962	C 101248
	C 101248 is a selective and potent inhibitor targeting both mouse and human tandem pore domain halothane-inhibited K+ channel 1 (THIK-1, IC50= 50 nM), without affecting the K2P family members (TREK-1, TWIK-2) and Kv2.1. ...
T63016	Nrf2 activator-4		Reactive Oxygen Species , Nrf2
	Nrf2 activator-4 is an Nrf2 activator that inhibits the production of reactive oxygen species in microglia for the treatment of fatty liver disease associated with metabolic dysfunction in humans.		Reactive Oxygen Species , Nrf2
T74779	JNJ-28583113
	JNJ-28583113, a TRPM2 antagonist with brain permeability, inhibits the phosphorylation of GSK3α and β subunits, thereby protecting cells from oxidative stress-induced cell death. Additionally, it suppresses cytokine rele...
T37697L	D-GsMTx4 TFA		TRP/TRPV Channel , Piezo Channel
	D-GsMTx4 TFA, a selective spider venom peptide, is a TRPC1/6 and Piezo2 inhibitor that inhibits cation-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families, blocks cation-selective s...		TRP/TRPV Channel , Piezo Channel
T72646	Asperbisabolane L
	Asperbisabolane L, a sesquiterpenoid, exhibits anti-inflammatory effects through the inhibition of the NF-κB-activated pathway. It prevents the translocation of NF-κB from the cytoplasm to the nucleus and also reduces NO...
T13036	Sulfosuccinimidyl oleate	Sulfo-N-succinimidyl oleate	Mitophagy
	Sulfosuccinimidyl oleate (Sulfo-N-succinimidyl oleate) (Sulfo-N-succinimidyl oleate) is a long chain fatty acid that inhibits fatty acid transport into cells. Sulfosuccinimidyl oleate is a potent and irreversible inhibit...		Mitophagy
T82763	CD33 splicing modulator 1 hydrochloride
	CD33 Splicing Modulator 1 Hydrochloride (Compound 1) is a myeloid lineage cell surface receptor CD33/Siglec 3 modulator involved in regulating microglia activity. This compound promotes exon 2 skipping in cellular mRNA p...
T35593	Semapimod tetrahydrochloride	CPSI-2364 tetrahydrochloride	TLR , MAPK
	Semapimod tetrahydrochloride (CPSI-2364 tetrahydrochloride) is a synthetic ornithine mitogen-activated protein kinase blocker and pro-inflammatory cytokine production inhibitor that interferes with macrophage and microgl...		TLR , MAPK
T83734	PapRIV TFA
	PapRIV, a quorum-sensing heptapeptide derived from B. cereus, undergoes synthesis as a 48-amino acid polypeptide. This compound is secreted and then extracellularly processed by NprB proteases into its active form. At co...
T62468	CB1/2 agonist 1
	CB1/2 agonist 1 is a potent CB1/2 agonist that crosses the blood-brain barrier, acting on CB1R (EC50: 56.15 nM) and CB2R (EC50: 11.63 nM). CB1/2 agonist 1 reduces glutamate release and LPS-induced microglia activation, a...
T78698	Aβ-IN-6
	Aβ-IN-6 is an orally active compound exhibiting anti-inflammatory, antioxidant, and anti-oligomeric activities, with significant implications for Alzheimer's disease (AD) research [1]. It effectively reduces the release ...
T35468	(±)19(20)-EDP Ethanolamide
	(±)19(20)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 108 and 280 nM for CB1 and CB2, respectively). It is produced through direct epoxygenation of docosahexaenoyl et...

Compounds

7BIO

T22012

Synonym:

Target: FLT, DYRK, Aurora Kinase

Tolebrutinib

T9125

Synonym: PRN2246,SAR442168

Target: Chloride channel, Mitochondrial Metabolism

GIBH-130

T4450

Synonym:

Target: IL Receptor, TNF, Interleukin

Synonym: MW 151,MW-151,MW012151SRM,MW151,MW01 2 151SRM

Target: Others

Sulfosuccinimidyl oleate sodium

T13036L

Synonym: Sulfo-N-succinimidyl oleate sodium

Target: Others

IMM-H004

T24161

Synonym: IMMH 004,IMMH-004,IMMH004

Anti-neuroinflammation agent 1

T79590

Synonym:

Target: NOD-like Receptor (NLR)

Synonym: N-Arachidoyl-D-sphingosine

Target: Endogenous Metabolite

Target: GNRH Receptor

Target: Reactive Oxygen Species, Nrf2

Target: TRP/TRPV Channel, Piezo Channel

Sulfosuccinimidyl oleate

T13036

Synonym: Sulfo-N-succinimidyl oleate

Target: Mitophagy

CD33 splicing modulator 1 hydrochloride

T82763

Synonym:

Target:

Semapimod tetrahydrochloride

T35593

Synonym: CPSI-2364 tetrahydrochloride

(±)19(20)-EDP Ethanolamide

T35468

Synonym:

Target:

カタログ番号	製品名	別名	ターゲット
T5575	Cycloastragenol	Cyclogalegenol,Astramembrangenin	Epigenetic Reader Domain , Telomerase
	Astramembrangenin (Cycloastragenol (Astramembrangenin)) is a triterpenoid saponin compound and a hydrolysis product of the main active ingredient in Astragalus membranaceus. Cycloastragenol (CAG) may have a novel therape...		Epigenetic Reader Domain , Telomerase
T5S2283	Sesamolin		p38 MAPK , Caspase , JNK
	1. Sesamolin and Sesamin has neuroprotective effect. 2. Sesamolin protects microglia against H2O2-induced cell injury, by inhibiting of p38 MAPK and caspase-3 activation and ROS production. 3. Sesamolin and Sesamin can s...		p38 MAPK , Caspase , JNK
TN1219	20-Hydroxyganoderic acid G
	20-Hydroxyganoderic acid G is a lanosterane triterpenoid obtained from the ethanolic extract of Ganoderma curtisii (Ganoderma curtisii) cotyledons. 20-Hydroxyganoderic Acid G inhibited LPS-activated BV-2 microglia, with ...
TJS1779	Protosappanin A	PTA	NADPH-oxidase , IL Receptor , IκB/IKK , TNF , NF-κB , TLR , ROS , COX , HIV Protease , JAK , NO Synthase , STAT
	Protosappanin A (PTA) has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IÎºB/NF-ÎºB inflammation signal pathway; it exerts anti-neuroinflammatory ...
T6S1917	Schisandrol B	Gomisin A,TJN-101,Besigomsin,Gamma-Schisandrin,Schizandrol B,Wuweizi alcohol-B	P450 , Reactive Oxygen Species , Autophagy
	1. Schisandrol B (Besigomsin) may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated NF-κB and MAPKs signaling pathways. 2. Schisandrol B has a...		P450 , Reactive Oxygen Species , Autophagy
T3826	Polygalasaponin F		NF-κB , TLR , Akt , PI3K
	Polygalasaponin F has anti-neuroinflammatory activity, can inhibit the release of inflammatory cytokines TNF-α and NO induced by lipopolysaccharides (LPS) and reduce the expression of inducible nitric oxide synthases. Po...		NF-κB , TLR , Akt , PI3K
TN3519	Bisdehydroneotuberostemonine		Others
	Bisdehydroneotuberostemonine shows significant inhibitory effect on lipopolysaccharide-induced nitric oxide production in BV2 microglia at 100 uM.		Others
T39385	15a-Hydroxy-3,11,23-trioxo-lanost-8,20-dien-26-oic acid
	15a-Hydroxy-3,11,23-trioxo-lanost-8,20-dien-26-oic acid is a Lanostane triterpenoid compound with the ability to inhibit NO production in LPS-induced microglia.
T39386	(3β,7β,12β,20Z)-3,7,12-Trihydroxy-11,15,23-trioxo-lanost-8,20-dien-26-oic acid
	(3β,7β,12β,20Z)-3,7,12-Trihydroxy-11,15,23-trioxo-lanost-8,20-dien-26-oic acid, a lanostane triterpenoid, demonstrates significant inhibitory effects on nitric oxide (NO) production in BV-2 microglia cells induced by n L...
T4S0823	Astragaloside		Others
	Astragaloside may protect against brain contusion and neuronal apoptosis after TBI by attenuating microglia activation in male rats. Astragalosides-induced apoptosis in NB4 cells may be associated with down-regulation of...		Others
TN5011	Shizukaol B		ERK , IL Receptor , p38 MAPK , TNF , NOS , NF-κB , COX , HIV Protease , DNA/RNA Synthesis , Prostaglandin Receptor , JNK
	Shizukaol B exerts anti-inflammatory effects in LPS-activated microglia partly by modulating JNK-AP-1 signaling pathway; it also shows significant anti-neuroinflammatory effects by inhibiting nitric-oxide (NO) production...
TN6524	Irilone
	Irilone has immunomodulatory, and α-amylase inhibitory activities, it exhibits the selective inhibition toward CYP3 A4 rather than other major human CYPs. Irilone exhibited prominent antioxidant activities with the IC50 ...
T5157	9,13-Epidioxy-8(14)-abieten-18-oic acid		Others
	9,13β-Epidioxy-8(14)-abieten-18-oic acid has anti-inflammatory activities, it exhibits moderate activities on NO levels in LPS-stimulated murine microglia BV2 cells, with IC50 values of 57.3 ± 0.2 uM. It is also a potent...		Others
TN2517	1,7-Dihydroxy-2,3-dimethoxyxanthone		Others
	1,7-Dihydroxy-2,3-dimethoxyxanthone may have medicinal use in the management of inflammation, asthma and allergy, it antagonises in a non competitive but, reversible manner the contractions induced by chemical inflammato...		Others
TN5901	Cudratricusxanthone A
	Cudratricusxanthone A has potent anti-proliferative, antioxidative, and monoamine oxidase inhibitory effects, it also possesses anti-cancer activities and provide a basis for developing effective therapeutic agents to in...
TN3587	Capillarisin		MMP , ERK , IL Receptor , BCL , VEGFR , TNF , NOS , NF-κB , TLR , MAPK , COX , DNA/RNA Synthesis , Prostaglandin Receptor , JNK , STAT
	Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cells, it inhibits cancer cell growth of osteosarcoma cells by ...
T37272	9(S),12(S),13(S)-TriHOME
	9(S),12(S),13(S)-TriHOME is a linoleic acid-derived oxylipin that has diverse biological activities.1,2,3,4It has been found in various plants and is produced in human eosinophils in a 15-lipoxygenase-dependent, soluble ...

天然物製品

Cycloastragenol

T5575

Synonym: Cyclogalegenol,Astramembrangenin

Target: Epigenetic Reader Domain, Telomerase

Sesamolin

T5S2283

Synonym:

Target: p38 MAPK, Caspase, JNK

20-Hydroxyganoderic acid G

Target: NADPH-oxidase, IL Receptor, IκB/IKK, TNF, NF-κB, TLR, ROS, COX, HIV Protease, JAK, NO Synthase, STAT

Schisandrol B

T6S1917

Synonym: Gomisin A,TJN-101,Besigomsin,Gamma-Schisandrin,Schizandrol B,Wuweizi alcohol-B

Target: P450, Reactive Oxygen Species, Autophagy

Polygalasaponin F

T3826

Synonym:

Target: NF-κB, TLR, Akt, PI3K

Bisdehydroneotuberostemonine

TN3519

Synonym:

Target: Others

15a-Hydroxy-3,11,23-trioxo-lanost-8,20-dien-26-oic acid

T39385

Synonym:

Target:

(3β,7β,12β,20Z)-3,7,12-Trihydroxy-11,15,23-trioxo-lanost-8,20-dien-26-oic acid

Target: ERK, IL Receptor, p38 MAPK, TNF, NOS, NF-κB, COX, HIV Protease, DNA/RNA Synthesis, Prostaglandin Receptor, JNK

9,13-Epidioxy-8(14)-abieten-18-oic acid

T5157

Synonym:

Target: Others

1,7-Dihydroxy-2,3-dimethoxyxanthone

TN2517

Synonym:

Target: Others

Cudratricusxanthone A

Target: MMP, ERK, IL Receptor, BCL, VEGFR, TNF, NOS, NF-κB, TLR, MAPK, COX, DNA/RNA Synthesis, Prostaglandin Receptor, JNK, STAT

9(S),12(S),13(S)-TriHOME

T37272

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-02424	Prolactin Protein, Mouse, Recombinant (His)	Mouse	Baculovirus-Insect Cells
	Prolactin (PRL) is a hormone with multiple actions in the central nervous system (CNS) spanning from physiology to pathology. PRL exerts different actions through its receptors that can be found in both neurons and glial...
TMPY-04778	Prolactin Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Prolactin (PRL) is a hormone with multiple actions in the central nervous system (CNS) spanning from physiology to pathology. PRL exerts different actions through its receptors that can be found in both neurons and glial...
TMPY-05446	CD200 Protein, Human, Recombinant (hFc)	Human	HEK293
	CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through ...
TMPY-01703	TREM-2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Triggering receptor expressed on myeloid cells 2 ( TREM2 ) is a single Ig domain receptor. It is expressed on macrophages and dendritic cells but not on granulocytes or monocytes. Its expression is most abundant in the b...
TMPY-00432	TREM-2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Triggering receptor expressed on myeloid cells 2 ( TREM2 ) is a single Ig domain receptor. It is expressed on macrophages and dendritic cells but not on granulocytes or monocytes. Its expression is most abundant in the b...
TMPY-01148	TREM-2 Protein, Human, Recombinant (His)	Human	HEK293
	Triggering receptor expressed on myeloid cells 2 ( TREM2 ) is a single Ig domain receptor. It is expressed on macrophages and dendritic cells but not on granulocytes or monocytes. Its expression is most abundant in the b...
TMPY-05053	ANGPTL2 Protein, Human, Recombinant (His)	Human	HEK293
	The angiopoietin-like protein (ANGPTL) family is homologous to angiopoietins but does not bind to the Tie2 receptor. The function of ANGPTLs has been elucidated largely in the context of angiogenesis and lipid metabolism...
TMPY-01253	LAMP1 Protein, Human, Recombinant (His)	Human	HEK293
	Lysosome-associated membrane glycoprotein 1, also known as CD107 antigen-like family member A, CD107a, and LAMP1, is a single-pass type I membrane protein that belongs to the LAMP family. CD107a is expressed largely in t...
TMPJ-00117	TREM-2 Protein, Human, Recombinant (mFc)	Human	Human Cells
	TREM2 is a cell surface receptor of the immunoglobulin superfamily. TREM2 is a type-1 transmembrane protein that shuttles to the plasma membrane where it exerts its cell autonomous biological functions. TREM2 undergoes r...
TMPJ-00115	TREM-2 Protein, Human, Recombinant (Avi & His), Biotinylated	Human	Human Cells
	TREM2 is a cell surface receptor of the immunoglobulin superfamily. TREM2 is a type-1 transmembrane protein that shuttles to the plasma membrane where it exerts its cell autonomous biological functions. TREM2 undergoes r...
TMPH-02231	NRROS Protein, Human, Recombinant (E. coli, His & Myc)	Human	E. coli
	Key regulator of transforming growth factor beta-1 (TGFB1) specifically required for microglia function in the nervous system. Required for activation of latent TGF-beta-1 in macrophages and microglia: associates specifi...
TMPH-02803	NRROS Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Key regulator of transforming growth factor beta-1 (TGFB1) specifically required for microglia function in the nervous system. Required for activation of latent TGF-beta-1 in macrophages and microglia: associates specifi...
TMPH-02230	NRROS Protein, Human, Recombinant (His & Myc)	Human	Baculovirus
	Key regulator of transforming growth factor beta-1 (TGFB1) specifically required for microglia function in the nervous system. Required for activation of latent TGF-beta-1 in macrophages and microglia: associates specifi...
TMPY-03653	CTRL Protein, Human, Recombinant (His)	Human	HEK293
	CTRL-1, also known as chymotrypsin-like protease, belongs to thepeptidase S1 family. CTRL-1 contains 1peptidase S1 domain. Its expression is increased in preeclampsia (PE). Placental-derived chymotrypsin-like protease is...
TMPK-01138	PLD4 Protein, Human, Recombinant (His)	Human	HEK293
	Phospholipase D4 (PLD4) is a newly identified protein expressed in microglia. the expression of PLD4 was located in macrophages in the colon cancer mesenchymal and lymph nodes as shown by immunohistochemical analysis. fu...
TMPK-01079	PLD4 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Phospholipase D4 (PLD4) is a newly identified protein expressed in microglia. the expression of PLD4 was located in macrophages in the colon cancer mesenchymal and lymph nodes as shown by immunohistochemical analysis. fu...
TMPK-00188	JAM-A Protein, Mouse, Recombinant (His)	Mouse	HEK293
	junctional adhesion molecule A (JAM-A), a cell adhesion molecule, is highly elevated in human GBM cancer stem cells and predicts poor patient prognosis. While JAM-A is also highly expressed in other cells in the tumor mi...
TMPJ-00851	IDE Protein, Human, Recombinant (His)	Human	Human Cells
	Insulin-Degrading Enzyme (IDE) is a secreted enzyme that belongs to the peptidase M16 family. IDE is a large zinc-binding protease and cleaves multiple short polypeptides that vary considerably in sequence. IDE plays a r...
TMPY-03732	CLM-9 Protein, Rat, Recombinant (His)	Rat	HEK293
	CLM-9, also known as TREM4, is a receptor which belongs to the TREM family. The TREM family of receptors regulates the activity of various cell types of the immune system including neutrophils, monocyte/macrophages, micr...
TMPY-03551	CLM-9 Protein, Human, Recombinant	Human	HEK293
	CLM-9, also known as TREM4, is a receptor which belongs to the TREM family. The TREM family of receptors regulates the activity of various cell types of the immune system including neutrophils, monocyte/macrophages, micr...
TMPY-03570	CLM-9 Protein, Human, Recombinant (His)	Human	HEK293
	CLM-9, also known as TREM4, is a receptor which belongs to the TREM family. The TREM family of receptors regulates the activity of various cell types of the immune system including neutrophils, monocyte/macrophages, micr...
TMPY-03217	CLM-9 Protein, Human, Recombinant (hFc)	Human	HEK293
	CLM-9, also known as TREM4, is a receptor which belongs to the TREM family. The TREM family of receptors regulates the activity of various cell types of the immune system including neutrophils, monocyte/macrophages, micr...
TMPK-00507	TREM2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	TREM-2 (Triggering Receptor Expressed on Myeloid cells-2) is a 35 kDa type I transmembrane member of the TREM family and Ig superfamily. Mature human TREM-2 consists of a 156 amino acid (aa) extracellular domain (ECD) w...
TMPJ-00288	TNF RII Protein, Human, Recombinant (mFc)	Human	Human Cells
	Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B) is a member of the tumor necrosis factor receptor superfamily. Human TNF RII contains four cysteinerich repeats in its ECD, which shares 58% and 56% amino a...
TMPJ-00189	TIM-3/KIM-3/HAVCR2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	Human Cells
	T cell immunoglobulin and mucin domain 3 is a member of the TIM family of immune regulating molecules. Mature cynomolgus TIM3 consists of a 182 amino acid (aa)extracellular domain (ECD), a 21 aa transmembrane segment, an...
TMPJ-00287	TNF RII Protein, Human, Recombinant (hFc)	Human	Human Cells
	Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B) is a member of the tumor necrosis factor receptor superfamily. Human TNF RII contains four cysteinerich repeats in its ECD, which shares 58% and 56% amino a...
TMPY-01712	C1QB Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Complement Component 1, q subcomponent (C1q) associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulon...
TMPY-06912	PU.1/SPI1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	SPI1 (also known as PU.1) is a dominant but transient regulator in early T-cell precursors and a potent transcriptional controller of developmentally important pro-T-cell genes. SPI1 is an essential transcription factor ...
TMPY-06917	PU.1/SPI1 Protein, Human, Recombinant (His)	Human	E. coli
	SPI1 (also known as PU.1) is a dominant but transient regulator in early T-cell precursors and a potent transcriptional controller of developmentally important pro-T-cell genes. SPI1 is an essential transcription factor ...
TMPJ-00292	CD36 Protein, Human, Recombinant (hFc)	Human	Human Cells
	Platelet Glycoprotein 4 (CD36) is an integral membrane glycoprotein that has multiple physiological functions. It is broadly expressed on a variety of cell types including microvascular endothelium, adipocytes, skeletal ...
TMPY-01733	SIGNR1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-02125	CCL6 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Chemokine (C-C motif) ligand 6 (CCL6), also known as C-C chemokine C10 has only been identified in rodents, which is a small cytokine belonging to the CC chemokine family, beta-chemokine subfamily. C-C chemokine C10 is i...
TMPY-06566	TREM-2 Protein, Human, Recombinant (hFc)	Human	HEK293
	Triggering receptor expressed on myeloid cells 2 ( TREM2 ) is a single Ig domain receptor. It is expressed on macrophages and dendritic cells but not on granulocytes or monocytes. Its expression is most abundant in the b...
TMPY-03595	CD200 Protein, Rhesus, Recombinant (His)	Rhesus	HEK293
	CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through ...
TMPY-01071	CD200 Protein, Human, Recombinant (His)	Human	HEK293
	CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through ...
TMPY-06598	TREM-2 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Triggering receptor expressed on myeloid cells 2 ( TREM2 ) is a single Ig domain receptor. It is expressed on macrophages and dendritic cells but not on granulocytes or monocytes. Its expression is most abundant in the b...
TMPY-06791	CD200 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through ...
TMPY-01160	CD200 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through ...
TMPY-03380	CD200 Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293
	CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through ...
TMPY-05638	CD200 Protein, Human, Recombinant (hFc & Avi)	Human	HEK293
	CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through ...
TMPY-05528	Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx), Biotinylated	Human	E. coli
	Apolipoprotein E (ApoE) is a 34.2 kDa glycosylated protein with 299 amino acid residues. There are three isoforms in human (apoE2, apoE3, and apoE4) due to different amino acid residues at positions 112 and 158. ApoE is ...
TMPY-05297	Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx)	Human	E. coli
	Apolipoprotein E (ApoE) is a 34.2 kDa glycosylated protein with 299 amino acid residues. There are three isoforms in human (apoE2, apoE3, and apoE4) due to different amino acid residues at positions 112 and 158. ApoE is ...
TMPH-00305	TGF-beta 1 Protein, Bovine, Recombinant (His)	Bovine	E. coli
	Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1,...
TMPH-01768	VGF Protein, Human, Recombinant (GST & His & Myc)	Human	E. coli
	Secreted polyprotein that is packaged and proteolytically processed by prohormone convertases PCSK1 and PCSK2 in a cell-type-specific manner. VGF and peptides derived from its processing play many roles in neurogenesis a...
TMPY-03998	ANGPTL2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	The angiopoietin-like protein (ANGPTL) family is homologous to angiopoietins but does not bind to the Tie2 receptor. The function of ANGPTLs has been elucidated largely in the context of angiogenesis and lipid metabolism...
TMPY-02916	LAMP1 Protein, Rat, Recombinant (hFc)	Rat	HEK293
	Lysosome-associated membrane glycoprotein 1, also known as CD107 antigen-like family member A, CD107a, and LAMP1, is a single-pass type I membrane protein that belongs to the LAMP family. CD107a is expressed largely in t...
TMPH-00354	CSF1R Protein, Feline, Recombinant (His & SUMO)	Feline	E. coli
	Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially monon...
TMPH-00382	TGF-beta 1 Protein, Chicken, Recombinant (His & SUMO)	Chicken	E. coli
	Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1,...