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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T15385 | Glibornuride | Potassium Channel | |
Glibornuride is an ATP-sensitive K+ channels (KATP channel) blocker ( pKi: 5.75). It is an antidiabetic agent. | |||
T9014 | SKI-178 | Apoptosis , S1P Receptor | |
SKI-178 is a sphingosine kinase 1 (SphK1) inhibitor with IC50 of 0.1-1.8 μM. It induces prolonged mitosis followed by apoptotic cell death through the intrinsic apoptotic cascade. The sustained activation of CDK1 during ... | |||
T9714 | Atpenin A5 | Potassium Channel | |
Atpenin A5 is a potent and highly specific complex II inhibitor (IC50 ~10 nM). Atpenin A5 is also an effective mKATP channel agonist and cardioprotective agent[1]. | |||
T4316 | ML365 | Potassium Channel | |
ML365 is a novel selective small molecule inhibitor of TASK1(KCNK3). | |||
T0343 | Nimodipine | BAY-e 9736 | Glucocorticoid Receptor , AhR , Calcium Channel , Autophagy |
Nimodipine (BAY-e 9736), a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells. | |||
T1781 | GW9508 | GW 9508 | GPR , Potassium Channel |
GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner. | |||
T26795 | PXS-4728A | BI-1467335,BI 1467335,BI1467335,BI-1467335 HCl | Monoamine Oxidase |
BI-1467335 HCl(BI 1467335) is a selective, orally active inhibitor of semicarbazide-sensitive amine oxidase (SSAO) that helps improve chronic obstructive pulmonary disease in mice[2]. | |||
T1198 | Tetracaine hydrochloride | Amethocaine hydrochloride,Amethocalne HCl,Tetracaine HCl | Calcium Channel , Sodium Channel |
Tetracaine hydrochloride (Amethocalne HCl) (Pontocaine), a potent local anaesthetic, is a channel function allosteric inhibitor. It is primarily used as an antipruritic and topically in ophthalmology, and it has been use... | |||
T1603 | Glipizide | CP 28720,K 4024 | Potassium Channel , PPAR , ABC |
Glipizide (CP 28720) is a short-acting, second-generation sulfonylurea with hypoglycemic activity. | |||
T1634 | Glibenclamide | Glyburide | Potassium Channel , Mitochondrial Metabolism , CFTR , P-gp , Autophagy |
Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide. | |||
T1952 | MK-2206 dihydrochloride | MK-2206 2HCl | Apoptosis , Akt , Autophagy |
MK-2206 dihydrochloride (MK-2206 2HCl) is a variant Akt inhibitor that inhibits Akt1, Akt2, and Akt3 (IC50=8/12/65 nM) with orally active, highly potent and selective potency. MK-2206 dihydrochloride exhibits antitumor a... | |||
T1101 | Minocycline hydrochloride | Minocycline HCl | HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic |
Minocycline hydrochloride (Minocycline HCl) is a tetracycline antibiotic with excellent absorption and tissue penetration that is used for several bacterial infections as well as treatment of acne. Minocycline hydrochlor... | |||
T11979 | McN5691 | RWJ26240 | Calcium Channel |
T23233L | RETF-4NA acetate | RETF-4NA acetate(1160928-63-1 free base) | Others |
RETF-4NA acetate is a sensitive, specific substrate for chymotrypsin. | |||
T14999 | CORM-401 | Others | |
CORM-401 is an oxidant-sensitive CO-releasing molecule. It can be used in oxidative stress-mediated pathologies and the research of inflammatory. | |||
T74235 | DHAPC | ||
DHAPC is a phospholipid that is very sensitive to oxidation [1] . | |||
T10566 | BMS-191095 | Potassium Channel | |
BMS-191095 is mitochondrial ATP-sensitive potassium (mitoKATP) channel activator. | |||
TQ0150 | Levcromakalim | (-)-Cromakalim,BRL 38227 | Potassium Channel |
Levcromakalim (BRL 38227) is an activator of the ATP-sensitive K+ channel. | |||
T20968 | CyPPA | Potassium Channel , Dopamine Receptor | |
CyPPA, a subtype-selective positive modulator of SK channels, decreased spontaneous firing rate, increased the duration of the apamin-sensitive afterhyperpolarization. | |||
T23563 | ZM 226600 | Potassium Channel | |
ZM 226600 is an ATP-sensitive potassium channel opener with an EC50 value of 500 nM. ZM226600 has an inhibitory effect on spontaneous bladder activity. | |||
T18974 | DiBAC4(3) | Others | |
DiBAC4(3) is a voltage-sensitive fluorescent dye (λem=505 nm, λex=490 nm). | |||
T20881 | 2-Iodobenzoic acid | o-Iodobenzoic acid,Kyselina o-jodbenzoova,2Iodobenzoic acid | Others |
2-Iodobenzoic acid (o-Iodobenzoic acid) is the impact-sensitive intermediate in the synthesis of the Dess-Martin periodinane. | |||
T11579 | HSL-IN-3 | HSL inhibitor 3,Ethyl 2-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)benzoate | Others |
HSL-IN-3 (HSL inhibitor 3) is a boronic acid derivative that is an inhibitor of hormone-sensitive lipase(HSL). | |||
T16448 | PD173212 | Calcium Channel | |
PD 173212 is a blocker that blocks N-type voltage sensitive calcium channel (Cav2.2). PD173212 (0.0017-1.7 μmol/kg, Intraperitoneal Injection.) dose-dependently reduced DNBS-induced visceral hypersensitivity in mice. | |||
T90604 | PCO 400 | ||
PCO 400 is an analog of comakalim that acts as a selective and potent ATP-sensitive K+ channel opener. | |||
T29067 | Upacicalcet | PLS-240,SK-1403,AJT-240 | Calcium Channel |
Upacicalcet (AJT-240) is an intraventricular calcium mimetic, a SHPT available for human hemodialysis, that inhibits excessive parathyroid hormone (PTH) secretion by directly acting on parathyroid cell membrane calcium-s... | |||
T18923 | BCIP | BCIP p-toluidine salt,X-phosphate p-toluidine salt | Others |
BCIP (BCIP p-toluidine salt) (BCIP p-toluidine salt) is an artificial chromogenic substrate. It is used for the sensitive colorimetric detection of alkaline phosphatase activity. | |||
T16420 | P-1075 | Potassium Channel | |
P-1075 opens mitochondrial K(ATP) channels and generates reactive oxygen species causing cardioprotection of rabbit hearts. P-1075 is an effective activator of sulfonylurea receptor 2-associated ATP-sensitive potassium c... | |||
T29541 | AC265347 | AC-265347 | CaSR |
AC265347 is a potent calcium-sensitive receptor (CaSR) agonist and ago-PAM orthosteric modulator with antitumour activity that inhibits neuroblastoma tumour growth by inducing differentiation.AC265347 can be used to stud... | |||
T21678 | 3MB-PP1 | PLK | |
3MB-PP1 is a bulky purine analog and a Polo-like kinase 1 (Plk1) inhibitor. In cells expressing analog-sensitive Plk1 alleles, 3MB-PP1 blocks mitotic progression and cell division arise by targeting Plk1. 3MB-PP1 specifi... | |||
T14994 | Coelenterazine h | 2-Deoxycoelenterazine,CLZN-h | Others |
Coelenterazine H is a synthetic derivative of coelenterazine (a light-emitting biomolecule).Coelenterazine h (CLZN-h) is more sensitive to Ca 2+ than is the native complex, thus providing a valuable tool for measuring sm... | |||
T37088L | Pep2m aceate | Others | |
pep2m aceate is a Peptide inhibitor of the interaction between the C-terminus of the GluR2 subunit and N-ethylmaleimide-sensitive fusion protein | |||
T12015 | Methyl homoveratrate | Others | |
Methyl homoveratrate, a McN5691 (RWJ-26240) metabolite detected in vivo in plasma, urine, and fecal extracts, functions as a voltage-sensitive calcium channel blocker. | |||
T9830 | GSK2556286 | GSK286 | Antibacterial |
GSK2556286 (GSK286) is an orally active inhibitor of Mycobacterium tuberculosis (M. tuberculosis).GSK2556286 inhibits the growth of human macrophages with an IC50 value of 0.07 μM.GSK2556286 is effective against both mul... | |||
T78409L | Boc-Val-Pro-Arg-MCA TFA | ||
Boc-Val-Pro-Arg-MCA TFA is a sensitive fluorescent substrate that is a thrombin substrate for the determination of trypsin-like serine protease activity. | |||
T3592 | MQAE | Others | |
MQAE, a fluorescent chloride ion indicator, is more sensitive and selective than 36Cl and microelectrode-based methods for chloride measurement in cells. MQAE is quenched via collision with chloride. | |||
T0902 | Ofloxacin | DL8280,Hoe-280,Floxin,Tarivid,Oxaldin | Topoisomerase , Antibacterial , Antibiotic |
Ofloxacin (Oxaldin) is a fluoroquinolone antibacterial antibiotic. Ofloxacin binds to and inhibits bacterial topoisomerase II (DNA gyrase) and topoisomerase IV, enzymes involved in DNA replication and repair, resulting i... | |||
T5364 | TBHQ | tert-Butylhydroquinone | Apoptosis , ERK , Others , Ferroptosis , Nrf2 , Autophagy |
TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2. | |||
T29067L | Upacicalcet HCl | Upacicalcet HCl(1333218-50-0 Free base) | CaSR |
Upacicalcet HCl is an intravesical calcium mimetic that inhibits excessive parathyroid hormone (PTH) secretion by directly acting on calcium-sensitive receptors in parathyroid cell membranes, thereby lowering PTH levels ... | |||
T0979 | Dequalinium chloride | Dequafungan,Danical,Decabis | Potassium Channel , PKC |
Dequalinium chloride (Decabis) , a topical bacteriostat, is a selective blocker of apamin-sensitive K+ channels. It is used in wound dressings and mouth infections and may also have antifungal action, but may cause skin ... | |||
TD0104 | Methyl purple | Others | |
Methyl purple is an introduced quinone-imide redox dye that has been shown to be an exceptionally sensitive monitor of photosystem I activity in chloroplasts. | |||
T6145 | ZM39923 hydrochloride | JAK3 Inhibitor IV,ZM 39923 HCl | EGFR , Others , JAK |
ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor with pIC50 of 4.4/7.1, almost no activity to JAK2 and modestly potent to EGFR; also found to be sensitive to transglutaminase. | |||
T37688 | Cyfluthrin | Reactive Oxygen Species , Sodium Channel | |
Cyfluthrin binds to voltage-sensitive sodium channel such as Nav 1.8 sodium channel and modify their gating kinetics, thereby disrupting nerve function of pests. | |||
T19709 | Nitrocefin | Others | |
Nitrocefin is an antibiotic. It being sensitive to hydrolysis by all lactamases produced by gram-positive and gram-negative bacteria. | |||
T20642 | Laurdan | 6-Dodecanoyl-2-dimethylaminonaphthalene | Others |
Laurdan (6-Dodecanoyl-2-dimethylaminonaphthalene) is a fluorescent membrane probe that is spectrally sensitive to the phospholipid phase of the cell membrane to which it binds. | |||
T60081 | BV02 | 2-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1,3-dioxoisoindoline-5-carboxylic acid | Others |
BV02 is an inhibitor of 14-3-3 protein-protein interactions and can be used in studies about the treatment of chronic myeloid leukemia. BV02 disrupts hematopoietic cells expressing the IM-resistant T315I mutation and the... | |||
T40996 | Coppersensor 1 | Coppersensor 1,CS1 | Others |
Coppersensor 1 (CS1) is a boron dipyrromethene-based fluorescent sensor for selective and sensitive detection of copper(I) ions (Cu + ) in biological samples. Coppersensor 1 can be imaged using any type of fluorescence m... | |||
T24398 | Lenaldekar | LDK | Akt , IGF-1R , S6 Kinase |
Lenaldekar (LDK) inhibits T-cell expansion and autoimmune encephalomyelitis. Lenaldekar causes dephosphorylation of members of the PI3 kinase/AKT/mTOR pathway and delays sensitive cells in late mitosis. | |||
TP1300 | GsMTx4 TFA (1209500-46-8 free base) | GsMTx4 TFA | Piezo Channel |
GsMTx4 TFA (1209500-46-8 free base) (GsMTx4 TFA) is a spider venom peptide that selectively inhibits cationic permeable mechanically-sensitive channels (MSCs) belonging to the Piezo and TRP channel families. | |||
T6587 | Mitiglinide Calcium | KAD-1229,S21403 | ATPase , Potassium Channel |
Mitiglinide Calcium (KAD-1229) is a blood glucose-lowering drugs, stimulating insulin secretion by closing the ATP-sensitive K+ channels in pancreatic beta-cells. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T1326 | Gentamicin sulfate | SCH9724,Gentamycin sulfate,NSC-82261 | ribosome , DHFR , Antibacterial , Antibiotic |
Gentamicin sulfate (SCH9724) is a wide-spectrum, aminoglycoside antibiotic used to inhibit protein synthesis in sensitive organisms. | |||
T0613 | 3-Hydroxyisovaleric acid | Beta-Hydroxyisovaleric acid | Others , Endogenous Metabolite |
3-Hydroxyisovaleric acid (Beta-Hydroxyisovaleric acid) is an endogenous metabolite excreted in the urine and can serve as an early and sensitive indicator of biotin deficiency. | |||
TN3790 | Dehydroabietinol | Pomiferin A,Dehydroabietyl alcohol | Antifection |
Dehydroabietinol (Pomiferin A) inhibits growth of chloroquine-sensitive as well as chloroquine-resistant strains of Plasmodium falciparum cultivated in erythrocytes in vitro (IC 50 26-27 microM). | |||
T3S0870 | Paederosidic acid methyl ester | ATPase , Potassium Channel , NO Synthase | |
Paederosidic acid methyl ester has antinociception, is possibly related to the pathway of NO-cGMP-ATP sensitive K(+) channels. | |||
T4S1876 | 3-Deoxyaconitine | Sodium Channel | |
3- Deoxyaconitine is a derivative of Aconitine (A189875), which activates tetrodotoxin-sensitive Na+ channels, inducing presynaptic depolarization, thus blocking the nerve action potential which, in turn, blocks the rele... | |||
T5S1389 | Escin IB | 5-HT Receptor , NO Synthase | |
Escin Ib inhibits gastric emptying, at least in part, mediated by capsaicin-sensitive sensory nerves, to stimulate the synthesis and/or release of dopamine, to act through central dopamine2 receptor, which in turn causes... | |||
T3929 | Kaurenoic acid | Kauren-19-Oic Acid,kaurenoate,kaur-16-en-18-oic acid | Others |
Kaurenoic acid (kaurenoate) has anti-inflammatory potential in acetic acid-induced colitis, decreases in MDA level. Kaurenoic acid exerts a uterine relaxant effect acting principally through calcium blockade and in part,... | |||
T2850 | Bicuculline | (+)-Bicuculline,d-Bicuculline | GABA Receptor |
Bicuculline ((+)-Bicuculline) is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungos... | |||
T4845 | L-Lactic acid | 2-HYDROXYPROPIONIC ACID,L-(+)-Lactic acid,(S)-2-Hydroxypropanoic acid | Endogenous Metabolite , Antibacterial , Antibiotic |
L-Lactic acid ((S)-2-Hydroxypropanoic acid) is a natural product produced by the anaerobic glycolysis of pyruvic acid. L-Lactic acid is a sensitive indicator of tissue hypoxia and can be used as a hemodynamic indicator i... | |||
T4869 | D-Allose | β-D-Allopyranose,D-(+)-ALLOSE | Others , Endogenous Metabolite |
D-Allose (β-D-Allopyranose) is a rare naturally occurring monosaccharide known to exert anti-proliferative effects on cancer cells. The effects of D-Allose on the cellular membranes of hormone-refractory prostate cancer ... | |||
T3682 | (-)-Catechin gallate | (-)-Catechin 3-O-gallate,(-)-Catechin 3-gallate | Others , COX |
(-)-Catechin gallate ((-)-Catechin 3-O-gallate) displays inhibition of 6PGD, IDH. (-)-Catechin gallate ((-)-Catechin 3-O-gallate) displays inhibition of human Beta-secretase. (-)-Catechin gallate ((-)-Catechin 3-O-gallat... | |||
T4S0553 | Theaflavin-3'-Gallate | Theaflavin 2B,THEAFLAVIN 3'-O-GALLATE | Others |
Theaflavin-3'-Gallate (Theaflavin 2B) usually comes from the leaves of Camellia sinensis (L.) O. Kuntze. Theaflavin-3'-gallate, act as prooxidants and induce oxidative stress, with carcinoma cells more sensitive than nor... | |||
TN1905 | Magnolioside | Antifection | |
Magnolioside has anti-plasmodial activity, shows notable growth inhibitory activity against chloroquine-sensitive strains of P. falciparum. It also shows a moderate antibacterial activity against Staphylococcus aureus CI... | |||
T0224 | Meropenem | SM 7338 | Others , Antibacterial , Antibiotic |
Meropenem (SM 7338) is a carbapenem antibiotic with broad spectrum of activity that is administered intravenously and used for severe bacterial infections due to sensitive agents. Meropenem is a common cause of mild tran... | |||
T4715 | 2'-Deoxyguanosine monohydrate | Guanine-2'-deoxyriboside | Others , Endogenous Metabolite |
2'-Deoxyguanosine monohydrate (Guanine-2'-deoxyriboside) is a nucleoside consisting of the base guanine and the sugar deoxyribose. It is like guanosine, but with one oxygen atom removed. It is a nucleoside component of D... | |||
T3051 | Theaflavin-3-gallate | Theaflavine-3-Gallate | Others |
Theaflavin-3-gallate (Theaflavine-3-Gallate) can play a role in decreased intestinal cholesterol absorption via inhibition of micelle formation. Theaflavin-3-gallate has anticancer and apoptotic effects in non-small cell... | |||
T5270 | 5-Methylcytosine | Others , DNA/RNA Synthesis , Endogenous Metabolite | |
5-Methylcytosine is a methylated nucleotide base found in eukaryotic DNA. In animals, the DNA methylation of cytosine to form 5-methylcytosine is found primarily in the palindromic sequence CpG. In plants, the methylated... | |||
T5219 | L-Alloisoleucine | L-allo-Isoleucine,(3R)-LS-Isoleucine,L(+)-Alloisoleucine | Others , Endogenous Metabolite |
L-Alloisoleucine (L-allo-Isoleucine) is a branched chain amino acid and is a stereoisomer of L-isoleucine. It is a common constituent of human plasma (albeit at low levels). L-alloisoleucine is produced as a byproduct of... | |||
TCS0102 | Pulegone | (+)-Pulegone | Calcium Channel , Endogenous Metabolite , TRP/TRPV Channel |
1. Pulegone ((+)-Pulegone) has cytotoxicity followed by regenerative cell proliferation is the MOA for Pulegone-induced urothelial tumors in female rats. 2. Pulegone induces a verapamil-sensitive psychostimulant effect t... | |||
T6S0735 | Flavokawain B | Flavokavain B,Flavokawin B,2'-Hydroxy-4',6'-Dimethoxychalcone | Apoptosis , Others |
1. Flavokawain B (Flavokavain B) has potent anti-inflammatory activity, can significantly inhibit production of NO and PGE2 in LPS-induced RAW 264.7 cells. 2. Flavokawain B, the hepatotoxic constituent from kava root, in... | |||
T3831 | Licoricone | Antifection | |
Licoricone exhibits anti-helicobacter pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains. | |||
TQ0072 | Warangalone | Scandenolone | PKA |
Warangalone is an anti-malarial compound that can inhibit the growth of both strains of parasite 3D7 (chloroquine-sensitive) and K1 (chloroquine-resistant) with IC50s of 4.8 μg/mL and 3.7 μg/mL, respectively. | |||
TN2271 | Thalrugosaminine | Antifection | |
Thalrugosaminine shows promising antibacterial activity with MIC values of 64-128ug/ml and Staphylococcus species is the most sensitive strains. Thalrugosaminine possesses hypotensive activity in rabbits and is active ag... | |||
T10609 | Brevetoxin-3 | PbTx-3 | Others |
TN4202 | (-)-Heraclenol | Antifection | |
(-)-Heraclenol shows in vitro anti-plasmodial activity against chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum.(-)-Heraclenol has moderate antibacterial and antifungal activities. | |||
TMA2418 | 1-Methoxyphaseollidin | PAFR , Antifection | |
1-Methoxyphaseollidin exhibits anti-Helicobacter pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains. 1-Methoxyphaseollidin may show moderate cytotoxic activity agains... | |||
TN4387 | Khellactone | Antifection | |
Khellactone shows antitumor activity,it can suppress the growth of NCI-H460 tumor cells. (+)-4'-cis-Khellactone and (+)-3'-cis-khellactone have antiplasmodial activities, they show notable inhibitory activity against -se... | |||
T37452 | Stephacidin B | ||
Stephacidin B is a fungal metabolite that has been found inA. ochraceus.1Dimeric stephacidin B is rapidly converted to a monomer, avrainvillamide ,in vitro.2Stephacidin B is cytotoxic to a variety of cancer cells, includ... | |||
TN4062 | Flavidin | COX , Prostaglandin Receptor | |
Flavidin shows very good antioxidant capacity. Flavidin can enhance fluorescent imaging, allowing more sensitive and specific cell labeling in tissues, it should have wide application in molecular detection, providing a ... | |||
TN4322 | Isopulegol | ATPase , Potassium Channel , GABA Receptor | |
Isopulegol presents depressant- and anxiolytic-like effects, it also has anticonvulsant and bioprotective effects against PTZ-induced convulsions are possibly related to positive modulation of benzodiazepine-sensitive GA... | |||
TN4552 | Methyl p-hydroxyphenyllactate | Others | |
Methyl para-hydroxyphenyllactate(MeHPLA) can suppress the cellular proliferation of estrogen-sensitive MCF-7 breast cancer cells in vitro and to suppress the growth of rat uteri in vivo, high affinity of MeHPLA for the t... | |||
T13123 | Tentoxin | Endogenous Metabolite | |
Tentoxin, a cyclic peptide produced by phytopathogenic fungi, inactivates the F1 motor in sensitive plants at nanomolar to micromolar concentrations, whereas higher concentrations surpass the natural activity of the enzy... | |||
TN6010 | Picrasidine S | ||
Picrasidine S shows the potent cytotoxicity against human HeLa cervical, gastric MKN-28, and mouse melanoma B-16 cancer cells, it also shows the potent antibacterial activity against two strains of pathogenic bacteria me... | |||
TN4183 | Hardwickiic acid | (-)-Hardwikiic acid | Sodium Channel |
Hardwickiic acid ((-)-Hardwikiic acid) is a natural compound derived from Pulicaria gnaphalodes and is an anti-injury receptor compound. hardwickiic acid blocks tetrodotoxin-sensitive voltage-dependent sodium channels. h... | |||
T35483 | 19,20-Epoxycytochalasin D | ||
19,20-Epoxycytochalasin D is a fungal metabolite that has been found in the endophytic fungus Nemania sp. UM10M. It is active against the chloroquine-sensitive and -resistant strains of P. falciparum (MIC = 0.4 ng/ml for... | |||
T72737 | Ganoderic acid R | ||
Ganoderic acid R, exhibiting notable anticancer properties, effectively hampers tumor growth through apoptosis induction in both multidrug resistance (MDR) tumor cell line (KB-A-1/Dox) and sensitive tumor cell line (KB-A... | |||
T81318 | R-30-Hydroxygambogic acid | ||
R-30-Hydroxygambogic acid, a polyprenylated xanthone epimer isolated from the gamboge of Garcinia hanburyi, exhibits cytotoxicity against human leukemia K562 cell lines, with IC50 values of 2.89 μM for the resistant stra... | |||
T70495 | Scytonemin | ||
Scytonemin is a biological pigment synthesized by many strains of cyanobacteria, including Calothrix sp., Lyngbya aestuarii, and others. Scytonemin is also a potent PKL1 inhibitor, which inhibits cell proliferation and a... | |||
TN4449 | Longistylin C | Antifection | |
Longistylin A and longistylin C show some cytotoxic effects, with IC(50) values of 0.7-14.7 microM against the range of cancer cell lines. Longistylin A and longistylin C, and betulinic acid show a moderately high in vit... | |||
TN3438 | Arborinine | HCV Protease , Antifection | |
Arborinine shows mild in vitro antibacterial activity, it possesses moderate levels of anti-hepatitis C virus(HCV) activities with the IC50 values being 6.4 ± 0.7 ug/ml. Arborinine shows antifeedant activity against Spod... | |||
T37219 | N-Palmitoyl Glycine | ||
The acyl amides are a family of endogenous lipids that act as potent modulators of pain and inflammation. The best characterized members of this family are the arachidonoyl amides, which includes N-arachidonoyl ethanolam... | |||
TN4402 | Labd-13-ene-8,15-diol | Antifection | |
13(E)-Labd-13-ene-8alpha,15-diol shows antiviral and anticancer activity, it shows strong anti-HRV2 and HRV3 activity with a 50% inhibitory concentration (IC50) of 2.68 and 0.87 microg/mL,respectively; it also exhibits a... | |||
T36915 | 21-Deoxycortisol | ||
21-Deoxycortisol is a corticosteroid metabolite of 17-hydroxyprogesterone produced in the adrenal glandvia11-hydroxylation by 11β-hydroxylase.1,2Serum levels of 21-deoxycortisol are elevated in patients with congenital a... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-03616 | NAPG Protein, Human, Recombinant (His) | Human | E. coli |
NAPG (NSF Attachment Protein Gamma, also known as gamma SNAP) is a Protein Coding gene. This gene encodes soluble NSF attachment protein gamma. The encoded protein mediates platelet exocytosis and controls the membrane f... | |||
TMPY-00151 | Alpha SNAP Protein, Human, Recombinant (His) | Human | E. coli |
NAPA (NSF Attachment Protein Alpha) is a Protein Coding gene. This gene encodes a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to ta... | |||
TMPH-03209 | CLNS1A Protein, Rabbit, Recombinant (His & Myc) | Rabbit | E. coli |
CLNS1A Protein, Rabbit, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 33.4 kDa and the accession number is Q28678. | |||
TMPJ-00379 | AOC3 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Membrane primary amine oxidase(AOC3), also known as vascular adhesion protein (VAP-1) and HPAO, this protein is a member of the semicarbazide-sensitive amine oxidase (SSAO) family. VAP-1 is a type 1 membrane-bound glycop... | |||
TMPJ-00380 | AOC3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Vascular adhesion protein-1(VAP-1) is a copper amine oxidase with a topaquinone cofactor.VAP-1 is a type II integral membrane protein, but a soluble form of the enzyme is present in human serum, and its level increases i... | |||
TMPH-00709 | DAHP synthase Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). DAHP synthase Protein, E. coli, Recombinant (His) is expressed... | |||
TMPK-00369 | HGF Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Hepatocyte growth factor (HGF) is an important component of the pathophysiology of IR, with increased levels in most common IR conditions, including obesity. HGF has a role in the metabolic flux of glucose in different i... | |||
TMPH-03231 | AFP2 Protein, Raphanus sativus, Recombinant (His & SUMO) | Raphanus sativus | E. coli |
Possesses antifungal activity sensitive to inorganic cations. Induces potential changes in fungal membranes and increased K(+) efflux and Ca(2+) uptake. AFP2 Protein, Raphanus sativus, Recombinant (His & SUMO) is express... | |||
TMPH-03044 | PBP1a Protein, MenB, Recombinant (His & SUMO) | MenB | E. coli |
Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-... | |||
TMPH-03652 | Ustilago maydis P6 virus (UmV6) KP6 killer toxin (His) | UmV6 | P. pastoris (Yeast) |
This protein is lethal to sensitive cells of the same or related species. The KP6 alpha subunit is known to recognize some cellular receptors before interaction of the complex with KP6 beta, precipitating cell death. Ust... | |||
TMPH-00346 | Limulus clotting factor C Protein, Carcinoscorpius rotundicauda, Recombinant (His) | Carcinoscorpius rotundicauda | E. coli |
This enzyme is closely associated with an endotoxin-sensitive hemolymph coagulation system which may play important roles in both hemostasis and host defense mechanisms. Its active form catalyzes the activation of factor... | |||
TMPK-00195 | TFPI Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Oestrogens influence the pathophysiology and development of hormone-sensitive cancers, such as breast cancer. Tissue factor pathway inhibitor (TFPI) is a serine protease inhibitor of the extrinsic coagulation pathway and... | |||
TMPH-03618 | Clotting factor C Protein, Tachypleus tridentatus, Recombinant (His & Myc) | Tachypleus tridentatus | E. coli |
This enzyme is closely associated with an endotoxin-sensitive hemolymph coagulation system which may play important roles in both hemostasis and host defense mechanisms. Its active form catalyzes the activation of clotti... | |||
TMPK-00751 | FSTL3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Follistatin-like 3 (FSTL3) is a novel cytokine that regulates insulin sensitivity and counteracts activin/myostatin signalling. In the present study, regulation of FSTL3 in renal dysfunction was investigated in both huma... | |||
TMPK-00194 | TFPI Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Oestrogens influence the pathophysiology and development of hormone-sensitive cancers, such as breast cancer. Tissue factor pathway inhibitor (TFPI) is a serine protease inhibitor of the extrinsic coagulation pathway and... | |||
TMPH-00701 | PBP1b Protein, E. coli, Recombinant (His & Myc) | E. coli | E. coli |
Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-... | |||
TMPJ-00888 | ANXA7 Protein, Human, Recombinant | Human | E. coli |
Annexin A7 (ANXA7) is a member of the annexin family of calcium-dependent phospholipid binding proteins. Annexin A7 has a unique, highly hydrophobic N-terminal domain and a conserved C-terminal region. The C-terminal reg... | |||
TMPH-00170 | PBP 4 Protein, Bacillus subtilis, Recombinant (His & SUMO) | Bacillus subtilis | E. coli |
Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-... | |||
TMPY-02025 | CPLX2 Protein, Human, Recombinant (His) | Human | E. coli |
Complexin-2 (CPLX2), a member of the complexin/synaphin family, is a soluble pre-synaptic protein believed to regulate neurotransmitter release from pre-synaptic terminals. Complexins are soluble proteins that regulate t... | |||
TMPJ-01174 | Cystatin B Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Cystatin B, also called stefin B or liver thiol proteinase inhibitor, is a member of family 1 of the cystatin superfamily. Like Cystatin A, it is an intracellular inhibitor regulating the activities of cysteine proteases... | |||
TMPK-01534 | Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human&Mouse, MHC (His & Avi) | Human & Mouse | HEK293 Cells |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel... | |||
TMPK-01530 | HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human, MHC (His & Avi), Biotinylated | Human | HEK293 Cells |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel... | |||
TMPK-01498 | HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Tetramer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel... | |||
TMPK-01535 | Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human&Mouse, MHC (His & Avi) | Human & Mouse | HEK293 Cells |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel... | |||
TMPK-01502 | HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Monomer Protein, Human, MHC (His & Avi), Biotinylated | Human | HEK293 Cells |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel... | |||
TMPK-01542 | HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel... | |||
TMPK-01503 | HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Monomer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel... | |||
TMPK-01533 | HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel... | |||
TMPJ-00934 | PRDX3 Protein, Human, Recombinant | Human | E. coli |
Thioredoxin-Dependent Peroxide Reductase Mitochondrial (PRDX3) is an enzyme that belongs to the AhpC/TSA family. Human and mouse PRDX3 genes are highly conserved, and they map to the regions syntenic between mouse and hu... | |||
TMPH-01410 | GPR84 Protein, Human, Recombinant (hFc) | Human | P. pastoris (Yeast) |
Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. Not activated by short-chain and ... | |||
TMPJ-00753 | Myoglobin Protein, Human, Recombinant (His) | Human | E. coli |
Myoglobin(MB) is a cytoplasmic protein expressed in myocytes of the heart and skeletal muscle that reversibly binds oxygen. It belongs to the globin family. Functions of myoglobin include oxygen storage and transport, as... | |||
TMPJ-00935 | PDIA3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
PDIA3 protein is also known as Protein disulfide-isomerase A3. It is a protein that in humans is encoded by the PDIA3 gene.PDIA3 is an enzyme that belongs to the endoplasmic reticulum and interacts with lectin chaperones... | |||
TMPJ-00604 | KIR2DL4 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Killer cell immunoglobulin-like receptor 2DL4(KIR2DL4) is a Single-pass type I membrane protein and contains 2 Ig-like C2-type (immunoglobulin-like) domains.It belongs to the immunoglobulin superfamily. KIR2DL4 is expres... | |||
TMPJ-00331 | IFNAR1 Protein, Rhesus macaque, Recombinant (His) | Rhesus | HEK293 Cells |
Interferon‑alpha/beta receptor 1 (IFN‑ alpha / beta R1), also known as IFNAR1, are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-... | |||
TMPH-00794 | Dps Protein, Helicobacter pylori, Recombinant (His & SUMO) | Helicobacter pylori | E. coli |
Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical produ... | |||
TMPY-06815 | SYAP1 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Synapse-associated protein 1 (SYAP1), also known as PRO3113 and BSTA, belongs to the synapse-associated BSD domain family, featuring three α-helices and two conserved tryptophan and phenylalanine residues located at the ... | |||
TMPY-02717 | GPR37 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
GPR37 (cathepsin Z) is an orphan receptor that belongs to the G-protein coupled receptor 1 family. G protein-coupled receptors are a large protein family comprised of transmembrane receptors that sense molecules outside ... | |||
TMPJ-00271 | SMAD3 Protein, Human, Recombinant (His & Flag) | Human | E. coli |
Mothers against decapentaplegic homolog 3(SMAD3) is a cytoplasm protein which belongs to the dwarfin/SMAD family. Smad proteins undergo rapid nuclear translocation upon stimulation by transforming growth factor and in so... | |||
TMPJ-00802 | THBS1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Thrombospondin-1 (TSP-1) is a 150-180kDa calcium-sensitive protein that is secreted as a disulfide-linked homotrimer. TSP-1 regulates a wide range of cellular functions including their interactions with other cells and w... | |||
TMPJ-00785 | FABP3 Protein, Human, Recombinant (His) | Human | E. coli |
Fatty Acid Binding Protein 3 (FABP3) is a small cytoplasmic protein (15 kDa) that is released from cardiac myocytes following an ischemic episode. Like the nine other distinct FABPs that have been identified, FABP3 is in... | |||
TMPY-01589 | Serpin B10 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus Insect Cells |
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesi... | |||
TMPJ-01137 | MIA Protein, Human, Recombinant (His) | Human | E. coli |
Melanoma Inhibitory Activity Protein (MIA) is an autocrine growth regulatory protein secreted from chondrocytes and malignant melanoma cells, which was the first discovered member of a family of secreted cytokines termed... | |||
TMPY-01176 | CIAP1 Protein, Human, Recombinant (Avi) | Human | E. coli |
The cellular inhibitor of apoptosis protein-1 (cIAP1) is a member of the Inhibitor of Apoptosis family proteins are (IAP) whose members are characterized by a novel domain of about 70 amino acids termed baculoviral IAP r... | |||
TMPY-02840 | Ubiquitin Activating Enzyme E1/UBA1 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
UBE1, also known as UBA1, belongs to the ubiquitin-activating E1 family. UBE1 gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cl... | |||
TMPJ-00990 | S100B Protein, Mouse, Recombinant (His) | Mouse | E. coli |
S100-B, is an acidic protein with a molecular weight of 21 kDa belonging to the S100 family. S100-B contains two EF-hand-type calcium-binding motifs separated by a hinge region with a hydrophobic cleft. S100-B plays an i... | |||
TMPY-02760 | CALML3 Protein, Human, Recombinant (His) | Human | E. coli |
Calmodulin-like protein 3 (CALML3) is similar to that of authentic calmodulin and may actually compete with calmodulin by binding, with different affinity, to cellular substrates. Calmodulin-like protein 3 (CALML3) is a ... | |||
TMPY-02043 | PARK7/DJ-1 Protein, Human, Recombinant (His) | Human | E. coli |
Parkinson's disease locus DJ-1 (PARK7) is a differentially expressed transcript. DJ-1 plays a physiologic role in protection of erythroid cells from oxidant damage, a function unmasked in the context of oxidative stress.... | |||
TMPY-03341 | ASF1B Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
The histone chaperone anti-silencing factor 1a (ASF1a) interacts with MDC1 and is recruited to sites of DSBs to facilitate the interaction of phospho-ATM with MDC1 and phosphorylation of MDC1, which are required for the ... | |||
TMPY-01674 | CRTAM Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Cytotoxic and regulatory T-cell molecule, also known as Class-I MHC-restricted T-cell-associated molecule and CRTAM, is a single-pass type I membrane protein which belongs to thenectin family.CRTAM contains oneIg-like... | |||
TMPY-02198 | ILKAP Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Integrin-linked kinase-associated serine/threonine phosphatase 2C, also known as ILKAP, is a cytoplasm protein that belongs to the PP2C family. ILKAP contains one PP2C-like domain. ILKAP is widely expressed. Highest leve... | |||
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カタログ番号 | 製品名 | ||
---|---|---|---|
L4900 | Cardiotoxicity Compound Library | 131 compounds | |
A unique collection of 131 cardiotoxicity inducing compounds for toxicological study; | |||
L5700 | Featured Fragment Library | 246 compounds | |
A unique collection of 246 fragment-like small molecules for FBDD; |