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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T10404 | ATP synthase inhibitor 1 | ATPase | |
ATP synthase inhibitor 1 is an inhibitor of the c subunit of the F1/FO-ATP synthase complex. It inhibits mitochondrial permeability transition pore (mPTP) opening and does not affect ATP levels. | |||
T10616 | BRM/BRG1 ATP Inhibitor-1 | Epigenetic Reader Domain | |
BRM/BRG1 ATP Inhibitor-1 is an allosteric dual Brahma homolog (BRM)/SWI/SNF related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 (SMARCA2) and BRG1/SMARCA4 ATPase activity inhibitor (IC50... | |||
T60032 | BRM/BRG1 ATP Inhibitor-2 | Epigenetic Reader Domain | |
BRM/BRG1 ATP Inhibitor-2 is an inhibitor of BRG1/BRM ATPase and can be used in studies about the treatment of BAF-related disorders. | |||
T40616 | 8-Azido-ATP | 8-Azidoadenosine 5'-triphosphate,8-N3-ATP,8-Azido-ATP | |
8-Azido-ATP is a nucleotide analog that demonstrates photo-reactivity properties. It offers utility in the precise labeling and identification of proteins, particularly those involved in DNA-dependent RNA polymerase acti... | |||
T39891 | 8-Bromo-ATP | 8-Bromoadenosine 5'-triphosphate,8-Bromo-ATP,8-Br-ATP | |
8-Bromo-ATP (8-Bromoadenosine 5'-triphosphate) is a purinergic P2X receptor agonist and an ATP analogue. It exhibits cytotoxicity towards multiple myeloma cells, with an IC50 of 23.1 μM. | |||
T40455 | 8-NH2-ATP | 8-Aminoadenosine-5'-O-triphosphate,8-NH2-ATP | |
8-NH2-ATP is an inactive derivative of adenosine triphosphate (ATP), synthesized from 8-NH2-Ado. It has been documented that 8-NH2-Ado exhibits potent properties, as evidenced by its ability to induce apoptosis-associate... | |||
T40696 | 2'-NH2-ATP | 2'-NH2-ATP,2'-Amino-2'-deoxyadenosine-5'-triphosphate | |
2'-NH2-ATP (2'-Amino-2'-deoxyadenosine-5'-triphosphate) is an adenosine derivative compound that acts as a weak competitive inhibitor of ATP with a K i value of 2.3 mM. It finds utility in nucleic acid labeling. | |||
T22496 | 2-Methylthio-ATP tetrasodium | 2-Methylthioadenosine triphosphate tetrasodium salt,2-methylthio-atp-tetrasodium | Others |
P2 purinoceptor agonist | |||
T17454 | ATP-polyamine-biotin | Others | |
ATP-polyamine-biotin is a cell-permeable, efficient kinase cosubstrate with conversions and kinetics similar to those of other known ATP analogues. APB shows a cytotoxicity EC50 value of 19 ± 1 mM. ATP-polyamine-biotin i... | |||
T22592 | ATPγS tetralithium salt | ATP-gamma-S tetralithium salt | PERK |
ATPγS tetralithium salt is a substrate for nucleotide hydrolysis and RNA unraveling activity of the eukaryotic translation initiation factor eIF4A, associated with p97 mutants and prions. | |||
T38444 | α,β-Methylene-ATP dilithium | ||
α,β-Methylene ATP dilithium, a phosphonic analog of ATP, serves as a ligand for P2X3 and P2X7 receptors. It is a potent agonist specifically targeting P2X1 and P2X3 receptors while exerting negligible activity on P2X2, P... | |||
T69111 | 2',3'-Dialdehyde ATP | ||
2',3'-Dialdehyde ATP is a derivative of, and the oxidized form of, ATP. It has been found to be a specific, irreversible inhibitor of component A3 of the methylreductase system which plays a role in processing amino acid... | |||
T18917 | ATP-Red 1 | Others | |
ATP-Red 1 is a multisite-binding switchable fluorescent probe. It can rapidly and selectively respond to intracellular concentrations of ATP in living cells. | |||
T40522 | 3'-Deoxy-3'-amino-ATP | ||
3'-Deoxy-3'-amino-ATP, an ATP analogue, is a highly effective and competitive inhibitor of ATP, exhibiting a K i value of 2.3 μM. Its application includes the synthesis of 3′-Amino-3′-deoxy transfer RNA by integrating it... | |||
TP2297 | TNP-ATP triethylammonium salt | Others | |
P2X receptor antagonist | |||
T13541 | α,β-Methylene ATP trisodium | Others | |
α,β-Methylene ATP trisodium is a ligand of P2X3 and P2X7 receptor. | |||
T22738 | DMNPE-caged ATP diammonium salt | Others | |
DMNPE-caged ATP | |||
T75325 | ATP dimagnesium | ||
Adenosine 5'-triphosphate (ATP) dimagnesium, a pivotal molecule in energy storage and metabolism, fuels metabolic pumps and acts as a coenzyme within cells. Additionally, it plays a significant role as an endogenous sign... | |||
T75326 | ATP ditromethamine | ||
ATP ditromethamine (Adenosine 5'-triphosphate ditromethamine), a vital in vivo energy storage and metabolic constituent, fuels metabolic pumps and acts as a cellular coenzyme. It also plays a crucial role as an endogenou... | |||
T74033 | 6-Me-ATP | ||
6-Me-ATP (N6-Methyl-ATP), a N6-modified adenosine triphosphate (ATP) derivative, exhibits strong binding affinity for glycogen synthase kinase 3 (GSK3) and acts as the phosphate group donor in GSK3β-catalyzed phosphoryla... | |||
T79586 | 3′-Acetate-ATP | ||
3’-Acetate-ATP, an analogue of ATP and its acetylation product, exhibits maximum ultraviolet absorption at 259 nm in neutral aqueous solutions. It impedes nucleic acid polymerization [1]. | |||
T83802 | TNP-ATP sodium | ||
TNP-ATP, a derivative of ATP, acts as an antagonist to the purinergic P2Y1, P2X3, and P2X2/3 receptors, demonstrating selectivity by showing lower inhibitory concentrations (IC50 = 6, 0.9, 7 nM, respectively) compared to... | |||
T74034 | 6-Me-ATP trisodium | ||
6-Me-ATP (N6-Methyl-ATP) trisodium, an N6-modified ATP derivative, demonstrates high binding affinity for GSK3 and effectively acts as the phosphate group donor in GSK3β-catalyzed phosphorylation of its substrate peptide... | |||
T82945 | ATP Synthesis-IN-1 | ||
ATP Synthesis-IN-1 (Compound 4), a quinoline derivative, potently inhibits PA ATP synthesis with an IC50 of 11.1μg/mL and exhibits antibacterial properties. This compound is utilized in studying drug-resistant PA infecti... | |||
T78639 | Oxidized ATP trisodium salt | oATP trisodium salt | P2X Receptor |
Oxidized ATP trisodium salt (oATP) is a broad-spectrum inhibitor of P2 receptors, irreversibly antagonizing P2X7R activation and inhibiting c-reactive protein (CRP)-induced NLRP3 inflammasome activation. It is utilized i... | |||
T61649 | ATP synthase inhibitor 2 | ||
ATP Synthase Inhibitor 2, a compound targeting Pseudomonas aeruginosa (PA) ATP synthase with an IC50 of 10 μg/mL, fully inhibits the ATP synthesis activity of PA at a concentration of 128 μg/mL [1]. | |||
T82944 | ATP Synthesis-IN-2 | ||
ATP Synthesis-IN-2 (Compound 5) serves as a potent inhibitor of ATP synthesis activity, displaying significant antibacterial properties with an IC50 value of 0.7 μg/mL against Pseudomonas aeruginosa (PA) [1]. | |||
T72590 | α,β-Methylene-ATP | ||
α,β-Methylene ATP, a phosphonic analog of ATP, functions as a ligand for P2X3 and P2X7 receptors. This compound acts primarily as a selective agonist for P2X1 and P2X3 receptors, exhibiting minimal to no activity on P2X2... | |||
T79004 | ATP synthase inhibitor 2 TFA | ||
ATP Synthase Inhibitor 2 (Compound 22) TFA is a potent inhibitor of Pseudomonas aeruginosa ATP synthase with an IC50 value of 10 μg/mL. It effectively halts ATP synthesis in Pseudomonas aeruginosa at a concentration of 1... | |||
T72257 | BRM/BRG1 ATP Inhibitor-3 | ||
BRM/BRG1 ATP Inhibitor-3 is a potent inhibitor targeting both BRM and BRG1 components of the BAF complex, exhibiting IC50 values of 10.4 nM for BRM and 19.3 nM for BRG1, respectively. It holds potential for research appl... | |||
T60877 | Mtb ATP synthase-IN-1 | ||
Mtb ATP synthase-IN-1 (compound 6ab) can be used in anti-mycobacterium research. Mtb ATP synthase-IN-1 shoys low cytotoxicity (Vero IC 50 > 64 μg/mL) and acceptable oral bioavailability that has good metabolic stability.... | |||
T72258 | BRM/BRG1 ATP Inhibitor-4 | ||
BRM/BRG1 ATP Inhibitor-4, a potent inhibitor of BRG1/BRM, is utilized in the research of cancers and BAF complex-related disorders. | |||
T83786 | 8-Chloroadenosine-5'-triphosphate sodium | 8-chloro ATP | |
8-Chloroadenosine-5’-triphosphate (8-chloro ATP), a potent metabolite of the anticancer agent 8-chloro cyclic AMP (cAMP) and a nucleotide derivative, is produced through the biotransformation of 8-chloro cAMP into 8-chlo... | |||
T40862 | Fludarabine triphosphate | F-ara-ATP | |
Fludarabine triphosphate (F-ara-ATP), the cytotoxic metabolite of Fludarabine phosphate , inhibits ribonucleotide reductase and DNA polymerase and ultimately leads to cellular apoptosis. | |||
T83811 | 2'(3')-O-Anthraniloyladenosine-5'-O-triphosphate sodium | 2'(3')-ANT-ATP | |
2'(3')-O-Anthraniloyladenosine-5'-O-triphosphate (2'-ANT-ATP) and its isomer 3'-ANT-ATP are fluorescent derivatives of ATP that spontaneously isomerize. Emitting a maximum light of 428 nm when excited at 330 nm in water,... | |||
T83808 | Sp-Adenosine-5'-O-(1-thiotriphosphate) sodium | Sp-ATP-α-S | |
Sp-Adenosine-5'-O-(1-thiotriphosphate) (Sp-ATP-α-S), an isomer of the ATP-α-S sulfur-containing nucleotide derivative and a purinergic P2Y1 receptor agonist, effectively increases calcium mobilization in HEK293 cells har... | |||
T83807 | Rp-Adenosine-5'-O-(1-thiotriphosphate) sodium | Rp-ATP-α-S | |
Rp-Adenosine-5'-O-(1-thiotriphosphate) (Rp-ATP-α-S), a sulfur-containing nucleotide derivative isomer and a purinergic P2Y1 receptor agonist, promotes calcium mobilization in HEK293 cells expressing the human P2Y1 recept... | |||
T15373 | Gboxin | ATPase , Mitochondrial Metabolism | |
Gboxin is an inhibitor of oxidative phosphorylation that targets glioblastoma,inhibits the activity of F0F1 ATP synthase, with antitumour activity. | |||
T83818 | Isoguanosine-5'-O-triphosphate sodium | 2-Hydroxyadenosine 5’-triphosphate,2-hydroxy ATP,isoGTP | |
Isoguanosine-5'-O-triphosphate, an isomer of guanosine 5'-triphosphate (GTP) and a phosphorylated derivative of crotonoside, does not promote microtubule assembly like GTP. At a concentration of 2 mM, it hampers transcri... | |||
T40456 | 8-Bromoadenosine 5'-triphosphate tetrasodium | 8-Br-ATP tetrasodium,8-Bromoadenosine 5'-triphosphate tetrasodium | |
8-Bromoadenosine 5'-triphosphate tetrasodium (8-Br-ATP tetrasodium) is a tetrasodium ATP analogue, serving as a vital element for energy storage and metabolic processes in living organisms. ATP, a central component in vi... | |||
T38511 | AWL-II-38.3 | Ephrin Receptor | |
AWL-II-38.3 is a highly effective inhibitor of EphA3, a receptor for ephrin-A. It demonstrates potent kinase inhibitory activity against EphA3 and does not show significant cellular activity against Src-family kinases or... | |||
T15385 | Glibornuride | Potassium Channel | |
Glibornuride is an ATP-sensitive K+ channels (KATP channel) blocker ( pKi: 5.75). It is an antidiabetic agent. | |||
T83830 | 2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate sodium | 2′-fluoro-2′-deoxy ATP,AfTP,2'-fluoro dATP | |
2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate is a fluorinated analog of ATP, the pivotal energy substrate for cellular metabolism, and acts as an inhibitor of E. coli RNA polymerase (Ki = 200 µM). | |||
T7424 | NDI-091143 | ATP Citrate Lyase | |
NDI-091143 is a potent and high-affinity human ATP-citrate lyase (ACLY) inhibitor with an IC50 of 2.1 nM (ADP-Glo assay),indirectly disrupting citrate binding via an unexpected mechanism of inhibition. | |||
T16861 | SB 204990 | ATP Citrate Lyase | |
SB 204990 is an effective and specific ATP citrate lyase enzyme inhibitor. | |||
T9626 | Cycloleucine | NMDAR | |
Cycloleucine is an antagonist of NMDA receptor associated glycine receptor with a Ki of 600 μM. Cycloleucine is also a competitive inhibitor of S-adenosyl-methionine mediated methylation with anxiolytic and cytostatic ef... | |||
T7545 | 6-Aminonicotinamide | Others | |
6-Aminonicotinamide (6-AN) is a well-established inhibitor of the NADP+-dependent enzyme. | |||
T8535 | GAK inhibitor 49 | Serine/threonin kinase | |
GAK inhibitor 49 is a highly selective and ATP-competitive cyclin G associated kinase (GAK) inhibitor (IC50: 56 nM; Ki: 0.54 nM ). | |||
T2337 | BMS-303141 | BMS 303141 | ATP Citrate Lyase |
BMS-303141 is a potent ATP-citrate lyase (ACL) inhibitor (IC50: 0.13 uM, human recombinant ACL). | |||
T2028 | NG 52 | NG52,NG-52,Compound 52 | CDK |
NG 52 (NG-52) is a cell-permeable, reversible, and ATP-compatible inhibitor of the cell cycle-regulating kinase Cdc28p and the related Pho85p kinase. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T20089 | ATP | Atipi,ATP disodium salt hydrate,Triphosphoric acid adenosine ester,Ara-ATP,Triphosphaden,Adenosine triphosphate;Ara-ATP,Adenosine triphosphate | Endogenous Metabolite |
ATP (Adenosine triphosphate) provides cellular energy, participates in overall energy balance, and maintains intracellular homeostasis. ATP can act as an extracellular signaling molecule through interactions with specifi... | |||
T2812 | ATP disodium salt hydrate | ATP disodium,ATP disodium salt,Adenosine disodium triphosphate | Others , Endogenous Metabolite |
ATP disodium salt hydrate (Adenosine disodium triphosphate) is a nucleoside triphosphate used in cells as a coenzyme often called the "molecular unit of currency" of intracellular energy transfer. | |||
T1352 | ATP disodium salt | Adenosine 5'-triphosphate disodium salt,ATP,ATP disodium,Adetide,Adenosine-Triphosphate,Disodium adenosine triphosphate | P2X Receptor , Endogenous Metabolite |
ATP disodium salt (Adenosine-Triphosphate) is a P2 purinoceptor agonist. | |||
T64980 | ATP disodium trihydrate | Adenosine-5'-triphosphate disodium trihydrate | Endogenous Metabolite |
ATP disodium trihydrate (Adenosine-5'-triphosphate disodium trihydrate) is an important substance for energy storage and metabolism in the body. It is an important endogenous signaling molecule in immunity and inflammati... | |||
T40526 | ATP dipotassium | Adenosine5'-triphosphatedipotassium | |
ATP dipotassium (Adenosine 5'-triphosphate dipotassium) is a vital compound involved in energy storage and metabolism within living organisms. It plays a crucial role in supplying metabolic energy for driving pumps and a... | |||
T11590 | (-)-Hydroxycitric acid | Garcinia acid | ATP Citrate Lyase |
(-)-Hydroxycitric acid (Garcinia acid) (Garcinia acid) is the principal acid of fruit rinds of Garcinia cambogia. It is a potent and competitive inhibitor of ATP citrate lyase. (-)-Hydroxycitric acid suppresses fatty aci... | |||
T6323 | Oligomycin A | MCH 32 | ATPase , Antibiotic , Antifungal |
Oligomycin A (MCH 32) is an inhibitor of ATP synthase, inhibits oxidative phosphorylation and all the ATP-dependent processes occurring on the coupling membrane of mitochondria. | |||
T11589 | Hydroxycitric acid tripotassium hydrate | Potassium citrate monohydrate | ATP Citrate Lyase , HIF/HIF Prolyl-Hydroxylase , HIF |
Hydroxycitric acid tripotassium hydrate (Potassium citrate monohydrate) effectively inhibits stones formation and also inhibits HIF, and has antioxidation, anti-inflammation, and anti-tumor effects. Hydroxycitric acid tr... | |||
T3S0156 | Atractyloside potassium salt | Atractyloside Dipotassium Salt | Others |
1. Atractyloside potassium salt (Atractyloside Dipotassium Salt) inhibits oxidative phosphorylation by blocking the transfer of adenosine nucleotides through the mitochondrial membrane. | |||
T12045 | (-)-Hydroxycitric acid lactone | Garcinia lactone | ATP Citrate Lyase |
(-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent.(-)-Hydroxycitric acid lactone was a potent inhibitor of ATP citrate lyase, which catalyzes the extramitochondrial cleavage of citrate to oxaloac... | |||
T5544 | 2-Furoic acid | Furan-2-carboxylic acid | Anti-infection , ATP Citrate Lyase , Endogenous Metabolite , Acyltransferase |
2-Furoic acid (Furan-2-carboxylic acid) 2-Furoic acid can reduce serum cholesterol and triglyceride levels and has anti-lipidemic effects. | |||
T0256 | Citric acid trilithium salt tetrahydrate | Lithium citrate tribasic tetrahydrate,Trilithium citrate tetrahydrate | Dehydrogenase , GSK-3 , HIF/HIF Prolyl-Hydroxylase , Antibacterial , GluR |
Citric acid trilithium salt tetrahydrate (Lithium citrate tribasic tetrahydrate) , the active component of Lithium, is a medicine used in the therapy of psychiatric disease. It has shown the effects of signaling pathways... | |||
T3981 | Acacetin | 4'-Methoxyapigenin,5,7-Dihydroxy-4'-methoxyflavone,Linarigenin | Apoptosis , IAP , COX , Autophagy |
Acacetin (5,7-Dihydroxy-4'-methoxyflavone) is an O-methylated flavone found in various plants, shows antinociceptive, anti-inflammatory, and antioxidant activity in various research models. | |||
TN2019 | Orobol | 3'-Hydroxygenistein,3’,4’,5,7-tetrahydroxy-isoflavon | BCL , Caspase , PI3K |
Orobol (3’,4’,5,7-tetrahydroxy-isoflavon) is an inhibitor of tyrosine-specific protein kinase and phosphatidylinositol turnover. Orobol inhibits PI3K isoforms with IC50s of 3.46-5.27 μM for PI3K α/β/γ/K/δ. Orobol exhibit... | |||
T40426 | Cytidine 5'-diphosphate trisodium salt | CDP | Others |
Cytidine 5'-diphosphate trisodium salt (CDP) can produce Cytidine triphosphate for synthesis of DNA and RNA through the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosp... | |||
T7475 | S-Adenosyl-L-methionine | AdoMet,Ademetionine,SAMe,S-Adenosyl methionine | Others , Endogenous Metabolite |
S-Adenosyl-L-methionine (Ademetionine) is an intermediate metabolite of methionine,for treatment of primary biliary cirrhosis and major depressive disorder. | |||
T0465 | Ellagic acid | Gallogen,Elagostasine | Hedgehog/Smoothened , Casein Kinase , Reactive Oxygen Species , Topoisomerase , Endogenous Metabolite , PKA , Syk , PKC , Carbonic Anhydrase |
Ellagic acid (Gallogen) is a fused four ring compound isolated from the kino of Eucalyptus maculata Hook and E. Hemipholia F. Muell. Activates Factor XII of the blood clotting system which also causes kinin release; used... | |||
T8170 | Carboxyatractyloside | Gummiferin,Carboxyatractyloside tripotassium salt | Others |
Carboxyatractyloside (Carboxyatractyloside tripotassium salt) is a natural product. It acts as an inhibitor of ADP/ATP carrier, inhibits mitochondrial ADP/ATP transport. | |||
T3S0870 | Paederosidic acid methyl ester | ATPase , Potassium Channel , NO Synthase | |
Paederosidic acid methyl ester has antinociception, is possibly related to the pathway of NO-cGMP-ATP sensitive K(+) channels. | |||
T3419 | Chelerythrine chloride | Apoptosis , BCL , PKC , Autophagy | |
Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect to ATP. | |||
T22300 | Creatine monohydrate | Methylguanidoacetic acid monohydrate | Others , Endogenous Metabolite |
Creatine monohydrate (Methylguanidoacetic acid monohydrate) is a key player in the phosphagen energy system, especially in muscle and the brain. Creatine monohydrate is the primary source of ATP during high-intensity, sh... | |||
T4888 | Phosphocreatine disodium hydrate | Phosphocreatine disodium salt hydrate | Others , Endogenous Metabolite |
Phosphocreatine disodium hydrate ishigh-energy phosphate reservoir in vertebrate and some invertebrate muscle; provides phosphate for ADP-ATP conversion | |||
T6680 | Staurosporine | Antibiotic AM-2282,AM-2282,CGP 41251 | Apoptosis , PKA , Antibacterial , Antibiotic , Src , PKC , Antifungal |
Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-Fgr, phosphorylase kinase and TAOK2. Staurosporine also induces... | |||
TL0009 | Coniferin | Coniferoside,Abietin | Others , Antifungal |
Coniferin (Abietin) has ATP-dependent transport activity and has anti-oxidation effects. Coniferin has preferred substrates for the coniferin beta-glucosidase, the chromogenic coniferin analogue show the exclusive presen... | |||
T25192 | Butyrolactone I | Olomoucin | CDK |
Butyrolactone I (Olomoucin) is an ATP-competitive inhibitor of CDK and cdc2 kinase family. Butyrolactone I shows antitumor effects in non-small cell lung, small cell lung, and prostate cancer cell lines. | |||
T17143 | Toyocamycin | Vengicide | Apoptosis , Others , IRE1 , Antibiotic , Antifungal |
Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM). Toyocamycin induces apoptosis. | |||
T5079 | Adenosine 5'-diphosphate sodium salt | Adenosine-5'-diphosphate trisodium salt,ADP sodium salt | Others , Endogenous Metabolite |
Adenosine 5'-diphosphate sodium salt (ADP sodium salt) is an adenine nucleotide that is phosphorylated into ATP by ATPase. This phosphorylation is a key part of cellular homeostatis as it allows for energy storage and is... | |||
Fr14207 | (-)-Isopulegol | Others | |
Isopulegol has antioxidant, and neuroactive properties. It also has gastroprotective effects induced by isopulegol appear to be mediated, at least in part, by endogenous prostaglandins, K+ATP channel opening and antioxid... | |||
T21494 | Oligomycin | HIF | |
Oligomycin is an antifungal antibiotic that is an inhibitor of H+-ATP synthetase. The Oligomycin blocks oxidative phosphorylation and the electron transport chain. Oligomycin inhibited HIF-1alpha expression in hypoxic tu... | |||
T3313 | D-Luciferin | Firefly luciferin,D-(-)-Luciferin | Others |
D-Luciferin (D-(-)-Luciferin) is a popular bioluminescent substrate of luciferase in the presence of ATP, used in luciferase-based bioluminescence imaging and cell-based high-throughput screening applications. | |||
T3929 | Kaurenoic acid | Kauren-19-Oic Acid,kaurenoate,kaur-16-en-18-oic acid | Others |
Kaurenoic acid (kaurenoate) has anti-inflammatory potential in acetic acid-induced colitis, decreases in MDA level. Kaurenoic acid exerts a uterine relaxant effect acting principally through calcium blockade and in part,... | |||
T0064 | Adenine | Vitamin B4,6-Aminopurine | DNA/RNA Synthesis , Endogenous Metabolite , AChR |
Adenine (6-Aminopurine), a purine derivative, is a nucleobase with various roles in biochemistry including cellular respiration, in the form of both the energy-rich ATP and NAD and FAD, and protein synthesis, as a chemic... | |||
T4739 | Sodium creatine phosphate dibasic tetrahydrate | Creatine phosphate disodium salt tetrahydrate | Others , Endogenous Metabolite |
Sodium creatine phosphate dibasic tetrahydrate (Creatine phosphate disodium salt tetrahydrate) mainly exists in the skeletal muscles of vertebrates. It is a substrate for the determination of creatine kinase and can be u... | |||
T20003 | Acridone | Antibacterial , ABC | |
Acridone could induce cell apoptosis, inhibited ABCG2 (ATP-binding cassette sub-family G member 2) protein, and adjusted hormone level. | |||
T1723 | Adenosine 5'-diphosphate | Adenosine diphosphate,adenosine pyrophosphate,ADP | Endogenous Metabolite |
Adenosine 5'-diphosphate (ADP) induces human platelet aggregation and non-competitively blocks the stimulated human platelet adenylate cyclase. | |||
T5067 | Flavin adenine dinucleotide disodium salt | Flavin Adenine Dinucleotide Disodium,FAD sodium salt,FAD-Na2 | Others , Endogenous Metabolite |
Flavin adenine dinucleotide disodium salt (FAD sodium salt) is a flavin dinucleotide that is synthesized when the AMP moiety from ATP is transferred onto riboflavin 5'-monophosphate. FAD functions as a coenzyme that faci... | |||
TN4883 | Quinine sulfate dihydrate | Others | |
Quinine sulfate dihydrate plays a major role in potassium channel blockers. It is also used as an antimalarial, anticholinergic, antihypertensive and a hypoglycemic agent. It inhibits mitochondrial ATP-regulated potassiu... | |||
T4786 | D-Ribose(mixture of isomers) | D-Ribose,D-(-)-Ribose | Others , Endogenous Metabolite |
D-Ribose(mixture of isomers) (D-(-)-Ribose), commonly referred to as simply ribose, is a five-carbon sugar found in all living cells. Ribose is not an essential nutrient because it can be synthesized by almost every tiss... | |||
T4883 | Creatine | Methylguanidoacetic acid | Endogenous Metabolite |
Creatine (Methylguanidoacetic acid) is an amino acid that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as creatinine in the urine. Creati... | |||
T4897 | Inosine-5'-triphosphate trisodium salt | ITP,Inosine 5'-triphosphate trisodium salt | Others , Endogenous Metabolite |
Inosine-5'-triphosphate trisodium salt (ITP) is used in studies on the impact of deamination of ATP and GTP by various enzymes and chemical processes. Inosine-5'-triphosphate trisodium salt (ITP) may be used as a substra... | |||
T10857 | Coenzyme A | Endogenous Metabolite | |
Coenzyme A is an obligatory cofactor in all living cells synthesized from pantothenate (Vitamin B5), adenosine triphosphate (ATP), and cysteine. | |||
T3228 | Fosfructose | D-fructose-1,6-diphosphate,Betulanonaprenol,4937-84-2,Diphosphofructose,Fructose 1,6-diphosphate,D-fructofuranose 1,6-bisphosphate,Esafosfan | Others , Endogenous Metabolite |
D-fructose-1,6-diphosphate (D-fructose-1,6-diphosphate), also known as Fosfructose, is a cytoprotective natural sugar phosphate. It functions by promoting anaerobic glycolysis, which generates adenosine triphosphate (ATP... | |||
T3375 | Verbascoside | Kusaginin,Acteoside,TJC160 | Apoptosis , PARP , Antibacterial , PKC , p53 , HSV |
Verbascoside (Kusaginin) is a protein kinase C inhibitor with antimicrobial, anti-inflammatory activities. | |||
T6354 | (+)-Usnic acid | D-Usnic Acid,(+)-Usniacin | Antiviral , Antibacterial , mTOR |
(+)-Usnic acid (D-Usnic Acid) is a naturally occurring dibenzofuran derivative found in several lichen species. | |||
T4737 | 2'-Deoxyadenosine-5'-monophosphate | D-AMP,2'-Deoxyadenosine 5'-monophosphate | Others , Endogenous Metabolite |
2'-Deoxyadenosine-5'-monophosphate (D-AMP) is a nucleoside comprised of adenine attached to a ribose (ribofuranose) moiety via a -N9-glycosidic bond. Deoxyadenosine monophosphate is a derivative of the common nucleic aci... | |||
T4826 | L-Histidine monohydrochloride monohydrat | Others , Endogenous Metabolite | |
Histidine (abbreviated as His or H) is an alpha-amino acid. The L-isomer is one of the 22 proteinogenic amino acids, i.e., the building blocks of proteins. It is classified as a charged, polar because of the hydrophilic ... | |||
T4861 | Trans-Aconitic acid | ATPase , Endogenous Metabolite | |
Trans-Aconitic acid is normally present in normal human urine, and it has been suggested that is present in larger amounts with Reye's syndrome and organic aciduria. trans-Aconitic acid is a substrate of enzyme trans-aco... | |||
T6369 | Adenine hemisulfate | Diadenine sulphate,Adenine sulfate,Adeninsulfat | DNA/RNA Synthesis , Endogenous Metabolite |
Adenine hemisulfate (Diadenine sulphate) is a sulfate salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry. | |||
T8061 | Citronellal | (±)-Citronellal | Others |
Citronellal ((±)-Citronellal) is a monoterpene predominantly formed by the secondary metabolism of plants, producing antithrombotic, antiplatelet, and antihypertensive activities. | |||
T36390 | Sodium oleate | Oleic acid sodium salt,Sodium oleate,cis-9-Octadecenoic acid sodium salt | ATPase |
Sodium oleate (cis-9-Octadecenoic acid sodium salt) (Oleic acid sodium) is an abundant monounsaturated fatty acid sodium. Sodium oleate is a Na+/K+ ATPase activator. | |||
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カタログ番号 | 製品名 | Species | Expression System |
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TMPY-02483 | ATP citrate lyase/ACLY Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
ATP citrate lyase, also known as Acly or Acl, is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is composed of two polymer chains which are polypeptides in human. ATP... | |||
TMPH-00524 | ATP-dependent DNA helicase dda Protein, Enterobacteria phage T4, Recombinant (His) | Enterobacteria phage T4 | E. coli |
DNA helicase that stimulates viral DNA replication and recombination. Plays a role in T4 DNA replication initiation by selecting and activating DNA origins. Acts by dissociating and reassociating with the DNA molecule be... | |||
TMPH-00581 | ATP-dependent Clp protease adapter protein ClpS Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. | |||
TMPH-02530 | ATP5B Protein, Mouse, Recombinant (His & Myc & SUMO) | Mouse | E. coli |
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respirator... | |||
TMPH-00964 | ATP5PB Protein, Human, Recombinant (His & Myc) | Human | E. coli |
ATP5PB Protein, Human, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-00967 | ATP5F1B Protein, Human, Recombinant (His & Myc & SUMO) | Human | E. coli |
ATP5F1B Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli. | |||
TMPH-03249 | ATP5F1B Protein, Rat, Recombinant (His & Myc) | Rat | E. coli |
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respirator... | |||
TMPH-00226 | ATPase subunit g Protein, Bovine, Recombinant (His & Myc) | Bovine | E. coli |
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respirator... | |||
TMPH-00966 | ATP5F1B Protein, Human, Recombinant (His) | Human | Yeast |
ATP5F1B Protein, Human, Recombinant (His) is expressed in Yeast. | |||
TMPH-00965 | ATP5F1A Protein, Human, Recombinant (His) | Human | E. coli |
ATP5F1A Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPH-00969 | ATP5O Protein, Human, Recombinant (GST) | Human | E. coli |
ATP5O Protein, Human, Recombinant (GST) is expressed in E. coli. | |||
TMPY-03609 | ATP5D Protein, Human, Recombinant (His) | Human | E. coli |
ATP5D is a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synth... | |||
TMPJ-00462 | NADK Protein, Human, Recombinant (His) | Human | E. coli |
NAD Kinase (NADK) is an enzyme that belongs to the NAD Kinase family. It is a widely expressed enzyme, but it is not detected in skeletal muscle. NADK converts Nicotinamide Adenine Dinucleotide (NAD+) into NADP+, through... | |||
TMPH-00968 | ATP5C1 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
ATP5C1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPY-05160 | PFKP Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
PFKP plays a critical role in cell proliferation in breast cancer cells. PFKP is necessary for starvation-mediated autophagy, glycolysis, and EMT, thereby promoting the malignant progression of OSCC. The Snail-PFKP axis ... | |||
TMPH-03284 | CD39 Protein, Rat, Recombinant (E. coli, His) | Rat | E. coli |
In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP.... | |||
TMPH-03503 | Adenylate kinase Protein, Shigella flexneri, Recombinant (His & Myc & SUMO) | Shigella flexneri | E. coli |
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. | |||
TMPH-00582 | Endopeptidase Clp Protein, E. coli, Recombinant (His & Myc) | E. coli | E. coli |
Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. | |||
TMPH-00574 | Adenylate cyclase Protein, E. coli, Recombinant (His) | E. coli | in vitro E. coli expression system |
Catalyzes the formation of the second messenger cAMP from ATP. Its transcript is probably degraded by endoribonuclease LS (rnlA), decreasing cAMP levels and the negative regulator Crp-cAMP, which then induces its own tra... | |||
TMPH-03283 | CD39 Protein, Rat, Recombinant (His) | Rat | Baculovirus |
In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP.... | |||
TMPH-00408 | ClpP Protein, Clostridium botulinum, Recombinant (His & SUMO) | Clostridium botulinum | E. coli |
ClpP Protein, Clostridium botulinum, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPH-00904 | Adenylate kinase 7 Protein, Human, Recombinant (His) | Human | Baculovirus |
Adenylate kinase 7 Protein, Human, Recombinant (His) is expressed in Baculovirus. | |||
TMPH-00981 | ABCB1 Protein, Human, Recombinant (His) | Human | E. coli |
ABCB1 Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPY-04479 | PFKM Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
PFK1, also known as PFKM, is a regulatory glycolytic enzyme. PFK1 converts fructose 6-phosphate and ATP into fructose 1,6-bisphosphate (through PFK-1), fructose 2,6-bisphosphate (through PFK-2) and ADP. It is a muscle-ty... | |||
TMPH-01902 | DDX60 Protein, Human, Recombinant (His) | Human | E. coli |
DDX60 Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPH-00980 | DHX33 Protein, Human, Recombinant (His) | Human | E. coli |
DHX33 Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPH-00787 | BtuD Protein, Halobacterium salinarum, Recombinant | Halobacterium salinarum | E. coli |
Required for corrinoid utilization. Probably part of the ABC transporter complex BtuCDF involved in cobalamin (vitamin B12) import. Probably responsible for energy coupling to the transport system. | |||
TMPH-00786 | BtuD Protein, Halobacterium salinarum, Recombinant (His) | Halobacterium salinarum | E. coli |
Required for corrinoid utilization. Probably part of the ABC transporter complex BtuCDF involved in cobalamin (vitamin B12) import. Probably responsible for energy coupling to the transport system. | |||
TMPH-00970 | ABCD1 Protein, Human, Recombinant (His) | Human | in vitro E. coli expression system |
ABCD1 Protein, Human, Recombinant (His) is expressed in in vitro E. coli expression system. | |||
TMPH-00209 | CLPP2 Protein, Borrelia burgdorferi, Recombinant (His & Myc) | Borrelia burgdorferi | E. coli |
Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. | |||
TMPJ-01145 | ABCB5 Protein, Human, Recombinant (Trx) | Human | E. coli |
ATP-binding cassette sub-family B member 5(ABCB5) is a plasma membrane-spanning protein. ABCB5 is principally expressed in physiological skin and human malignant melanoma. ABCB5 has been suggested to regulate skin progen... | |||
TMPH-00979 | DDX3Y Protein, Human, Recombinant (His & Myc) | Human | Baculovirus |
DDX3Y Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus. | |||
TMPH-00976 | DDX19A Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
DDX19A Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPH-01900 | DDX5 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre-mRNA in the stem-loop r... | |||
TMPH-00975 | DDX1 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
DDX1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-00977 | DDX3X Protein, Human, Recombinant (B2M & His) | Human | E. coli |
DDX3X Protein, Human, Recombinant (B2M & His) is expressed in E. coli. | |||
TMPH-01901 | DDX53 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
DDX53 Protein, Human, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-00978 | DDX3X Protein, Human, Recombinant (His & Myc) | Human | Baculovirus |
DDX3X Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus. | |||
TMPH-02133 | DDX39B Protein, Human, Recombinant (GST) | Human | E. coli |
Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mR... | |||
TMPH-00974 | DHX9 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
DHX9 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPH-01711 | ABCC1 Protein, Human, Recombinant (His) | Human | E. coli |
Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs a... | |||
TMPH-00973 | DHX36 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
DHX36 Protein, Human, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPY-03788 | ATP1B1 Protein, Human, Recombinant (His) | Human | HEK293 |
ATP1B1 belongs to the family of Na+/K+and H+/K+-ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. ATP1B1 is a subunit of Na+/K+-ATPase. Na+/K+-ATPase is an integral membrane protein responsible for es... | |||
TMPH-01892 | ATP4A Protein, Human, Recombinant (His & Myc) | Human | E. coli |
The catalytic subunit of the gastric H(+)/K(+) ATPase pump which transports H(+) ions in exchange for K(+) ions across the apical membrane of parietal cells. Uses ATP as an energy source to pump H(+) ions to the gastric ... | |||
TMPH-02310 | ATP6V0D1 Protein, Human, Recombinant (GST) | Human | E. coli |
Subunit of the integral membrane V0 complex of the lysosomal proton-transporting V-type ATPase (v-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providin... | |||
TMPH-01893 | ATP4B Protein, Human, Recombinant (GST) | Human | E. coli |
The beta subunit of the gastric H(+)/K(+) ATPase pump which transports H(+) ions in exchange for K(+) ions across the apical membrane of parietal cells. Plays a structural and regulatory role in the assembly and membrane... | |||
TMPH-01894 | ATP4B Protein, Human, Recombinant | Human | E. coli |
The beta subunit of the gastric H(+)/K(+) ATPase pump which transports H(+) ions in exchange for K(+) ions across the apical membrane of parietal cells. Plays a structural and regulatory role in the assembly and membrane... | |||
TMPY-04137 | ATP6V1F Protein, Human, Recombinant (GST) | Human | E. coli |
ATP6V1F encodes a component of vacuolar ATPase mediating acidification. The cDNA and the genomic sequences of ATP6V1F were cloned successfully for the first time from the Giant Panda (Ailuropoda melanoleuca) using revers... | |||
TMPY-06599 | ATP1B4 Protein, Human, Recombinant (His) | Human | E. coli |
ATP1B4 is a member of the X(+)/potassium ATPases subunit beta family. It is highly expressed in skeletal muscle and at a lower level in heart. ATP1B4 gene can be found in all vertebrate genomes sequenced to date. However... | |||
TMPY-01118 | SLC27A4/FATP4 Protein, Human, Recombinant (His) | Human | HEK293 |
SLC27A4/ATG4B complex might act as a new potential therapeutic target of lung tumor chemotherapy. The solute carrier 27A (SLC27A) gene family encodes fatty acid transport proteins (FATPs) and includes 6 members. Autism s... | |||
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カタログ番号 | 製品名 | ||
---|---|---|---|
L2521 | Glycolysis Compound Library | 555 compounds | |
555 glycolysis-related active compounds for high-throughput and high-content screening. | |||
L1600 | Kinase Inhibitor Library | 2700 compounds | |
A unique collection of 2700 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases; | |||
L1610 | FDA-Approved Kinase Inhibitor Library | 263 compounds | |
A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening. | |||
L8300 | Chromatin Modification Compound Library | 250 compounds | |
A unique collection of 250 compounds targeting chromatin remodeling pathway for high throughput screening (HTS) and high content screening (HCS); | |||
L1120 | AMPK-Targeted Compound Library | 80 compounds | |
80 well-chosen unique AMPK-targeted small molecules; | |||
L5300 | Mitochondria-Targeted Compound Library | 812 compounds | |
A unique collection of 812 promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine; | |||
L2550 | Glutamine Metabolism Compound Library | 565 compounds | |
A unique collection of 565 glutamine metabolism related compounds can be used for high throughput screening (HTS) and high content screening (HCS), and also is an effective tool for research in glutamine metabolism and ... |