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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T5513 | RO-3 | P2X Receptor | |
RO3 is a selective antagonist of homomeric P2X3 and heteromeric P2X2/3 receptor | |||
T26745 | BAY 73-1449 | BAY-73-1449,BAY73-1449 | Others |
BAY-73-1449 is an antagonist of prostacyclin receptor. | |||
T1504 | Silodosin | KAD 3213,KMD 3213 | Adrenergic Receptor |
Silodosin (KAD 3213) is an alpha-Adrenergic Blocker. The mechanism of action of silodosin is as an Adrenergic alpha-Antagonist. | |||
T6991 | Nitroprusside disodium dihydrate | Sodium Nitroferricyanide(III) Dihydrate,Sodium Nitroprusside Dihydrate | Guanylate cyclase , Autophagy |
Nitroprusside disodium dihydrate (Sodium Nitroprusside Dihydrate) is a potent vasodilator working through releasing NO spontaneously in blood. | |||
T0703 | Flavoxate hydrochloride | Flavoxate HCl,NSC-114649,DW61,Rec-7-0040 | AChR |
Flavoxate hydrochloride (DW61) , a muscarinic AChR antagonist, is used in the therapy of various urinary syndromes and as an antispasmodic. | |||
T64006 | Lipid-lowering agent-1 | ||
Lipid-lowering agent-1 is a potent lipid-lowering agent that significantly inhibits the pharmacological effects of low-density lipoprotein cholesterol (LDLC) and promotes the production of high-density lipoprotein choles... | |||
T8529 | WYC-210 | Others | |
WYC-210 is a retinoid compound,and with lower anticancer activity | |||
T22316 | Doxazosin | UK 33274 | Adrenergic Receptor |
Doxazosin (UK 33274) is a long-lasting inhibitor of α1-adrenoceptors that is widely used to treat benign prostatic hyperplasia and lower urinary tract symptoms. | |||
T15251 | Etebenecid | Urelim | Others |
Etebenecid (Urelim) is uricosuric agents, which lower uric acid levels in the body by increasing the elimination of uric acid by the kidneys. It also inhibits penicillin tubular secretion. | |||
T19794 | Temafloxacin | Omniflox | Antibiotic |
Temafloxacin (Omniflox) is an antibiotic and antimycobacterial agent. It used to treat lower respiratory tract infections, genital and urinary infections like prostatitis, and skin infections. | |||
TP2104L | UFP 803 acetate | Neurotensin Receptor | |
UFP 803 acetate is a potent ligand of urotensin-II (UT) receptor. UFP-803 displays the activity of a lower residual agonist. | |||
T15102 | Dexamethasone palmitate | DXP | Glucocorticoid Receptor |
Dexamethasone palmitate (DXP), a lipophilic prodrug of Dexamethasone, shows a 47-fold lower affinity for the glucocorticoid receptor than Dexamethasone. Dexamethasone palmitate is a glucocorticoid receptor agonist and an... | |||
T6565 | Levobetaxolol hydrochloride | Betaxon,(S)-Betaxolol hydrochloride,AL-1577A,Levobetaxolol HCl | Adrenergic Receptor |
Levobetaxolol hydrochloride ((S)-Betaxolol hydrochloride) is a beta-adrenergic receptor inhibitor (beta blocker), used to lower the pressure in the eye in treating conditions such as glaucoma. | |||
T1423 | 3-Methylsalicylic acid | Hydroxytoluic acid,o-Cresotic acid | COX |
3-Methylsalicylic acid (o-Cresotic acid) is a long-acting salicylate derivative with antilipidemic properties. Hydroxytoluic acid has been shown to lower plasma free fatty acid and cholesterol levels. | |||
T6728 | VUF 10166 | 5-HT Receptor | |
VUF10166 is a novel, potent and competitive antagonist for 5-HT3A receptor with Ki of 0.04 nM, its affinity at 5-HT3AB receptor is significantly lower. | |||
T10000 | (±)-Tazifylline | Histamine Receptor | |
(±)-Tazifylline is a selective and long-acting antagonist of histamine H1 receptor. Tazifylline shows much lower affinity for H2 receptors, α- and β-adrenoceptors, 5-hydroxytryptamine and muscarinic receptor subtypes. | |||
T20381 | Cetyl glycol | NSC-71525,NSC 71525,NSC71525 | Others |
Cetyl glycol (NSC-71525) favors the decomposition of the metal-organic precursor, formation of an intermediate Co(2+)Fe(3+)-oleate complex, and the nucleation of nanoparticles at lower temperatures. Cetyl glycol is a red... | |||
T63166 | LSN3318839 | LSN-3318839,LSN 3318839 | Glucagon Receptor |
LSN3318839 is a potent and orally available glucagon-like peptide-1 receptor (GLP-1R) modulator.LSN3318839 enhances GLP-1R G-protein-coupled signaling and can be used to lower blood glucose. | |||
T13140 | Umbralisib R-enantiomer | TGR-1202 R-enantiomer,RP5264 R-enantiomer | PI3K |
Umbralisib R-enantiomer (RP5264 R-enantiomer) is a delta inhibitor of PI3K and a less active enantiomer of TGR-1202. The IC50 of Umbralisib R-enantiomers against δPI3 kinase is at least 20 times lower than that of the in... | |||
T2119 | Venetoclax | GDC-0199,ABT 199,ABT-199,ABT199 | BCL , Autophagy |
Venetoclax (ABT-199) is a Bcl-2 inhibitor (Ki<0.01 nM) with potent, selective, and orally active properties. Venetoclax has a 3-order-of-magnitude lower affinity for Bcl-xL and Bcl-W (Kis=48/245 nM). Venetoclax induces a... | |||
T29037 | UC-781 | NSC 675186,UC781,UC 781 | Antiviral , HIV Protease |
UC-781 (NSC-675186) is a potent and selective inhibitor of human immunodeficiency virus HIV-1 non-nucleoside reverse transcriptase (NNRTI) I with a C50 value of 5 nM.UC-781 exhibits both antiviral activity and drug resis... | |||
T3978 | Linerixibat | GSK2330672,Iinerixibat | HBV |
Linerixibat (GSK2330672) is a highly effective, nonabsorbable ASBT inhibitor (IC50: 42 ± 3 nM). It can lower glucose in an animal model of type 2 diabetes and shows excellent developability properties. | |||
T40229 | SR-0813 | Epigenetic Reader Domain | |
SR-0813 is a potent and selective inhibitor of the YEATS domain in ENL/AF9. It has an IC 50 of 25 nM and EC 50 of 205 nM for the ENL YEATS domain and an IC 50 of 311 nM and EC 50 of 76 nM (CETSA) for the AF9 YEATS domain... | |||
T11174 | (R)-Elagolix | NBI-56418 | GNRH Receptor |
(R)-Elagolix (NBI-56418) is a short-acting, nonpeptide, GnRH antagonist with an IC50 and Ki of 0.25 and 3.7 nM, respectively. administered orally, that unlike injectable depot GnRH agonists and antagonists, produces a do... | |||
T14298 | Rimiducid | Apoptosis , Others , Fatty Acid Synthase | |
Rimiducid is a lipid-permeable tacrolimus analogue, homodimerizing an analogue of human protein fkbp12 and binding to wild-type fkbp12 with 1000-fold lower affinity. Rimiducid is a dimerizer agent that acts by cross-link... | |||
T15300 | Fluorofenidone | AKF-PD | Others |
Fluorofenidone (AKF-PD) attenuates the progression of renal interstitial fibrosis partly by suppressing NADPH oxidase and extracellular matrix (ECM) deposition via the PI3K/Akt signalling pathway. Fluorofenidone is an an... | |||
TQ0271 | Falnidamol | BIBX 1382 | EGFR |
Falnidamol (BIBX 1382) is an orally active, selective EGFR tyrosine kinase inhibitor with an IC50 of 3 nM. Falnidamol displays > 1000-fold lower potency against ErbB2 (IC50=3.4 μM) and a range of other related tyrosine k... | |||
T0197 | Terazosin hydrochloride | Terazosin HCl,Terazosine,Blavin,Hytrin,Zayasel,Fosfomic | Adrenergic Receptor |
Terazosin hydrochloride (Hytrin) , a selective alpha1-antagonist, can treat the benign prostatic hyperplasia (BPH). It also can lower blood pressure, so it is a drug of choice for patients with prostate enlargement and h... | |||
T22029 | AL 34662 | 5-HT Receptor , Adrenergic Receptor | |
AL 34662 is a selective and potent 5-HT2A receptor agonist with IC50s of 0.77 nM and 1.5 nM for rat and human 5-HT2 receptors, respectively.AL 34662 is also a low affinity α-1D adrenergic agonist, with an EC50 of 0.4 μM.... | |||
T3625 | Bempedoic acid | ETC1002,ESP-55016,ETC 1002,ETC-1002 | ATP Citrate Lyase , AMPK |
Bempedoic acid (ETC1002) is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C and to avoid side effects associated with existing LDL-C lowering therapies. Bempedoic ... | |||
T7218 | Endomorphin 2 | Opioid Receptor | |
Endomorphins-2 (EM-2) could decrease both the frequency and amplitude of the sEPSC of the motoneurons in lamina IX, which was reversed by the MOR antagonist CTOP. EM-2-IR fibers originated from primary afferent fibers f... | |||
T20765 | Atorvastatin | HMG-CoA Reductase , Autophagy | |
Atorvastatin is an orally active HMG-CoA reductase inhibitor that has the ability to effectively lower blood lipids by activating liver cytochrome p450 to accelerate metabolism. Atorvastatin inhibited proliferation and i... | |||
T9417L | Gamma-preprotachykinin amide (72-92) acetate | gamma-preprotachykinin amide (72-92) acetate (114882-65-4 Free base) | Others |
gamma-preprotachykinin amide (72-92) acetate is a 21 amino acid peptide belonging to the tachykinin (TK) family and including neurokinin A (NKA) in its C-terminal sequence. gamma-preprotachykinin amide (72-92) acetate po... | |||
T23265 | RS 67333 hydrochloride | RS 67333 (hydrochloride),RS 67333 HCl | 5-HT Receptor |
RS 67333 hydrochloride (RO5203648) is a potent, selective partial agonist of the 5-HT4 receptor (5-HT4R) with a pKi value of 8.7 in guinea-pig striatum. It demonstrates lower binding affinities for other receptors, inclu... | |||
T0267 | Zonisamide | AD 810,CI 912 | Calcium Channel , Sodium Channel , Carbonic Anhydrase |
Zonisamide (AD 810), a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures. It may inhibit a carbonic anhydrase although this is not one of the main mechanisms... | |||
T0918 | Trimebutine | Mebutin | Opioid Receptor |
Trimebutine (Mebutin) is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu-opioid agonist effects. It is marketed for the treatment of irritabl... | |||
T0006 | Methylene Blue trihydrate | Methylthionine chloride,Basic blue 9,Methylene Blue | Guanylate cyclase , Microtubule Associated , NO Synthase , Parasite , Monoamine Oxidase |
Methylene Blue trihydrate (Basic blue 9) is a compound consisting of dark green crystals or crystalline powder, having a bronze-like luster. Solutions in water or alcohol have a deep blue color. Methylene Blue trihydrate... | |||
T32692 | Levamlodipine hydrobromide | Levamlodipine HBr | |
Levamlodipine hydrobromide is a medication used to lower blood pressure and prevent chest pain. | |||
T0231L3 | Amlodipine besylate monohydrate | ||
Amlodipine besylate monohydrate is a medication used to lower blood pressure and prevent chest pain. | |||
T11018 | DHMEQ racemate | rel-DHMEQ | NF-κB |
DHMEQ racemate is an NF-κB inhibitor. The activity of DHMEQ racemate is lower than (-)-DHMEQ. | |||
T27437 | GS-462808 | GS462808,GS 462808 | |
GS-462808 is a late sodium current inhibitor of the cardiac Nav1.5 channel. GS-462808 had lower brain penetration and serendipitously lower activity at the brain isoforms. | |||
T13442 | (R)-BAY1238097 | Others | |
(R)-BAY1238097 is the R-isomer with lower activity of BAY1238097. BAY1238097 is a selective BET inhibitor. | |||
T0231L | Amlodipine hydrochloride | Amlodipine HCl | |
Amlodipine hydrochloride is a salt of Amlodipine --- a medication used to lower blood pressure and prevent chest pain. | |||
T32504 | L-732531 | L732531,L 732531 | |
L-732531 is a tacrolimus-related immunosuppressant with lower toxicity. | |||
T8663L | Nifenalol | ||
Nifenalol is an adrenergic beta-blocker with good antiarrhythmic properties. It tends to lower blood pressure and provide protection against angina. | |||
T32691 | Levamlodipine hydrochloride | ||
Levamlodipine hydrochloride is a medication used to lower blood pressure and prevent chest pain. | |||
T29997 | Amlodipine adipate | CJ11828,CJ 11828,CJ-11828 | |
Amlodipine adipate is a medication used to lower blood pressure and prevent chest pain. | |||
T29999 | Amlodipine camsylate | ||
Amlodipine camsylate is a medication used to lower blood pressure and prevent chest pain. | |||
T30001 | Amlodipine besylate, (R)- | ||
Amlodipine besylate, (R)- is a medication used to lower blood pressure and prevent chest pain. | |||
T27418 | Glybuzole | Desaglybuzole,Sulfamidothiodiazol,Gludiase,Glybuzolum | |
Glybuzole is a sulfonamide derivative, it is able to lower blood glucose levels by increasing the release of insulin from pancreatic beta cells. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T6263 | Safflower-yellow | Others | |
Safflower yellow is extracted from the flowers of the plant safflower (Carthamus tinctorius) and as the traditional Chinese medicine it has been extensively used for the treatment of cardio cerebrovascular diseases. | |||
T19056 | Safflower yellow | Saffron powder,Carthamas yellow | Others |
Safflower yellow (Saffron powder) is extracted from the flowers of the plant safflower (Carthamus tinctorius). As traditional Chinese medicine, safflower has been extensively used for the treatment of cardio-cerebrovascu... | |||
T1134 | Clofoctol | Antibacterial , Antibiotic | |
Clofoctol is a bacteriostatic antibiotic with activity against Gram-positive bacteria, used in the treatment of upper and lower respiratory tract infections. | |||
T6000 | Delta-Tocopherol | D-DELTA-TOCOPHEROL | Endogenous Metabolite |
Delta-Tocopherol is an isomer of Vitamin E,has antioxidant activity,and might be useful as effective ingredients in whitening cosmetics with lower skin toxicity. | |||
T21383 | D-Thyroxine | Dethyrona,Detyroxin,Dextroid,Dextrothyroxine;Biotirmone,Dextroxin,Biotirmone,Debetrol,Dextrothyroxine | Others |
D-Thyroxine (Dextroxin) could lower cholesterol and also increases hepatic lipase which in turn improves utilization of triglycerides, leading to improve apolipoprotein E cholesterol particles. | |||
T0254 | Probucol | DH-581 | Virus Protease , ABC , Lipid |
Probucol (DH-581), an anti-hyperlipidemic drug, can lower the level of cholesterol in the bloodstream by increasing the LDL catabolic rate. | |||
TN2230 | Soyasaponin Ba | Others | |
Soyasaponin Ba may represent viable candidates for effective vaccine adjuvants due to their higher and lower or non-haemolytic effects.Soyasaponins Ab and Bb prevent scopolamine-induced memory impairment in mice without ... | |||
T5735 | Methyl deacetylasperulosidate | Deacetyl asperulosidic acid methyl ester,6α-Hydroxygeniposide | Others |
Methyl deacetylasperulosidate (6α-Hydroxygeniposide) is a natual product isolated from the herbs of Hedyotis diffusa Willd,it can lower the blood glucose level in normal mice. | |||
T2698 | Asperosaponin VI | Akebia saponin D,Asperosaponin Ⅵ | Apoptosis , Others , Caspase |
Asperosaponin VI (Akebia saponin D) , the most abundant constituent of the rhizome of Dipsacus asper, has been used for the treatment of lower back pain, traumatic hematoma and bone fractures. | |||
T5S1982 | Periplocin | Periplocoside | Apoptosis , Others |
1. Periplocin (Periplocoside) has anti-cancer effects on lung cancer cells, induces apoptosis and inhibits growth of cancer cells by the beta-catenin/Tcf signaling pathway. 2. Periplocin is used for treatment of rheumato... | |||
TN1622 | Ermanin | NOS , Influenza Virus , COX , HIV Protease , Antibacterial , Antibiotic | |
Ermanin is a flavonoid isolated from Tanacetum microphyllum.Ermanin inhibits platelet aggregation and has anti-tuberculosis and anti-viral/bacterial properties.Ermanin has anti-inflammatory activity by inhibiting the exp... | |||
T41095 | (E)-3-(4-Methoxyphenyl)acrylic acid | Glucosidase | |
(E)-3-(4-Methoxyphenyl)acrylic acid is a small molecule compound isolated from the rhizome of Etlingera pavieana (Pierre ex Gagnep.) R. M. Sm. It is a novel α-glucosidase inhibitor. (E)-3-(4-Methoxyphenyl)acrylic acid ha... | |||
T4000 | (±)-Equol | Equol,(R,S)-Equol | Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Drug Metabolite |
(±)-Equol ((R,S)-Equol) is a non-steroidal estrogen produced from the metabolism of the isoflavonoid phytoestrogen daidzen by human intestinal microflora. The estrogen receptor (ER) agonist activity of the naturally occu... | |||
T3795 | Corilagin | Apoptosis , TLR , Reverse Transcriptase , Antibacterial , Autophagy | |
Corilagin has anti-inflammatory activity. Corilagin has a significant antitumour potential and lower toxicity in normal cells in vitro.Corilagin can enhance the cytotoxicity of both cisplatin and doxorubicin on the Hep3B... | |||
T1437 | D-Panthenol | D-Pantothenyl alcohol,Ilopan,Dexpanthenol,Pantothenol | Endogenous Metabolite |
D-Panthenol (D-Pantothenyl alcohol) is an alcoholic analogue of D-pantothenic acid and cholinergic agent. D-Panthenol acts as a precursor of coenzyme A necessary for acetylation reactions and is involved in the synthesis... | |||
T4S0145 | Corylifol A | Corylinin | hCE , STAT , UGT |
1. Corylifol A (Corylinin) displays cytotoxic activity against HepG2 and Hep3B hepatocellular carcinoma cell lines, with IC50 values of 4.6 and 13.5 ug/ml, respectively. 2. Corylifol A and Biochanin A can be the potentia... | |||
T4877 | L-Homocystine | Endogenous Metabolite | |
Homocystine is the double-bonded form of homocysteine, but it occurs only transiently before being converted to the harmless cystathionine via a vitamin B6-dependent enzyme. Increasing evidence supports a role for an ele... | |||
T5S0106 | Peimisine | Ebeiensine | RAAS , AChR |
1. Peimisine (Ebeiensine) can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax tracheal smooth muscle and relieve asthma. 2. Pe... | |||
T0256 | Citric acid trilithium salt tetrahydrate | Lithium citrate tribasic tetrahydrate,Trilithium citrate tetrahydrate | Dehydrogenase , GSK-3 , HIF/HIF Prolyl-Hydroxylase , Antibacterial , GluR |
Citric acid trilithium salt tetrahydrate (Lithium citrate tribasic tetrahydrate) , the active component of Lithium, is a medicine used in the therapy of psychiatric disease. It has shown the effects of signaling pathways... | |||
TN3260 | 8(14),15-Isopimaradien-3-ol | Calcium Channel , Antifection | |
ent-8(14),15-pimaradien-3beta-ol (8(14),15-Isopimaradien-3-ol) can induce vascular relaxation. It displays high antibacterial activities (MIC values lower than 10 microg /mL for most pathogens). | |||
TN4974 | Scutebata B | Others | |
Scutebata B inhibited NO production efficiently with IC50 values of lower than 50 μM. | |||
TN2193 | Scutebarbatine W | Others | |
Scutebarbatine W can inhibit nitric oxide production efficiently with IC50 values of lower than 50 μM, it may have potential effects on the reduction of neuroinflammation. | |||
TN5448 | Steppogenin | Norartocarpanone | |
Steppogenin exhibits significant tyrosinase inhibition activity, ;it also shows strong mushroom tyrosinase inhibitory activity with IC(50) values lower than 50 microM, more potent than kojic acid (IC(50) = 71.6 microM), ... | |||
TN2194 | Scutebarbatine X | Others | |
Scutebarbatine X can inhibit nitric oxide production efficiently with IC50 values of lower than 50 μM, it may have potential effects on the reduction of neuroinflammation. | |||
TN1242 | 3,3'-Di-O-methylellagic acid | 3,8-Di-O-methylellagic acid | Others , TNF , Antifection |
3,3'-Di-O-methylellagic acid reveals moderate antibacterial activity, it also shows strong DPPH radical scavenging activities with SC50 of 123.3 ug/mL. It has a lower capacity of stimulating murine peritoneal macrophages... | |||
T13756 | Liquiritigenin-7-apiosylglucoside | Liquiritigenin-7-O-β-D-glucopyranosyl-(1→2)-β-D-apiofuranoside | Others |
Liquiritigenin-7-O-β-D-glucopyranosyl-(1→2)-β-D-apiofuranoside, a flavonoid extracted from Glycyrrhiza roots, exhibits lower cytotoxic effects on a variety of tumor and normal cells. | |||
TMA0127 | Ficusin A | transporter , PPAR | |
Ficusin has antioxidant, antilipidemic and antidiabetic effects, it can lower the levels of fasting blood glucose, plasma insulin, body weight gain in HFD-STZ induced diabetic rats, and can significantly enhance the PPAR... | |||
T82339 | Gangliotetraose | Gg4 | |
Gangliotetraose (Gg4), a tetrasccharide, predominantly comprises GM1 and its sialylated derivatives, which play a crucial role in modulating nuclear Ca2+ efflux and maintaining lower nuclear Ca2+ levels in differentiated... | |||
T79975 | Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside | HBV | |
Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside (Compound 1), a lignan with anti-HBV activity, exhibits selectivity by targeting the HBV surface antigen (HBsAg) with an IC50 of 0.58 mM, whereas its activity ag... | |||
T83597 | (+)-Menthyl acetate | ||
(+)-Menthyl acetate, extracted from the essential oil of Cunila angustifolia Benth, exhibits selective cytotoxicity, demonstrating higher efficacy against the MCF-7 cell line with an IC50 of 34.0 μg/mL and lower efficacy... | |||
T82031 | Isoguaiacin | ||
Isoguaiacin, a natural product [1], exhibits (hass) the potential to be (to exist as) an (a) effective pharmacological agent due to its (its) ability to inhibit (the inhibition of) mushroom tyrosinase. This (The) inhibit... | |||
TN4223 | Homopterocarpin | Antifection | |
Homopterocarpin and Pterocarpus extract offer gastroprotection against indomethacin- induced ulcer by antioxidative mechanism and the modulation of gastric homeostasis, homopterocarpin may be responsible for, or contribu... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-04826 | LILRB5/CD85c Protein, Human, Recombinant (His) | Human | HEK293 Cells |
A genetic variant in LILRB5 (leukocyte immunoglobulin-like receptor subfamily-B) (rs12975366: T > C: Asp247Gly) has been reported to be associated with lower creatine phosphokinase (CK) and lactate dehydrogenase (LDH) le... | |||
TMPY-03855 | DNase I Protein, Human, Recombinant (His) | Human | HEK293 Cells |
DNase1, also known as deoxyribonuclease I and DNL1, is a member of the DNase family. DNaseI is a nuclease that cleaves DNA preferentially at phosphodiester linkages adjacent to a pyrimidine nucleotide, yielding 5'-phos... | |||
TMPY-02580 | Histone H1 Protein, Human, Recombinant (His) | Human | E. coli |
H1 histone family, member 0 (H1F0) is a member of the H1 histone family of nuclear proteins which are a component of chromatin in eukaryotic cells. It's involved in maintaining the structure of chromatin by packing the "... | |||
TMPJ-00037 | FGF-2 Protein, Mouse, Recombinant | Mouse | E. coli |
FGF basic is one of 22 mitogenic proteins of the FGF family, which show 35-60% amino acid conservation. Unlike other FGFs, FGF acidic and basic lack signal peptides and are secreted by an alternate pathway. The 17 kDa mo... | |||
TMPJ-01065 | Noggin/NOG Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Mouse Noggin cDNA encodes a 232 amino acid (aa) residue precursor protein with 19 aa residue putative signal pept... | |||
TMPH-02488 | ACSS2 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids. Acetate is the preferred substrate but can also utilize propionate with a much lower affinity. ACSS2 Protein, Mouse, Recombinant (His) is expressed in E... | |||
TMPY-03508 | XTP3TPA Protein, Human, Recombinant (His) | Human | E. coli |
DCTPP1 hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. It has a strong preference for modified dCTP. DCTPP1’s activity is highest with 5-iodo-dCTP, followed by 5-bromo-d... | |||
TMPH-01756 | Neurofibromin/NF1 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Stimulates the GTPase activity of Ras. NF1 shows greater affinity for Ras GAP, but lower specific activity. May be a regulator of Ras activity. Neurofibromin/NF1 Protein, Human, Recombinant (His & Myc) is expressed in E.... | |||
TMPH-01816 | OX1R Protein, Human, Recombinant (His & SUMOstar) | Human | P. pastoris (Yeast) |
Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding. OX1R Protein, Human, Recombi... | |||
TMPY-04567 | SRPK1 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
Serine / threonine-protein kinase SRPK1, also known as SFRS protein kinase 1, Serine/arginine-rich protein-specific kinase 1, SR-protein-specific kinase 1 and SRPK1, is a cytoplasm and nucleus protein that belongs to the... | |||
TMPH-03722 | Coagulase/fibrinolysin Protein, Yersinia pestis, Recombinant (His & Myc) | Yersinia pestis | E. coli |
Seems to play an essential role in plague transmission by mediating flea blockage in a temperature-dependent fashion. Fibrinolytic activity prevails at 37 degrees Celsius whereas coagulase expression predominates at lowe... | |||
TMPH-01861 | LHPP Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Phosphatase that hydrolyzes imidodiphosphate, 3-phosphohistidine and 6-phospholysine. Has broad substrate specificity and can also hydrolyze inorganic diphosphate, but with lower efficiency. LHPP Protein, Human, Recombin... | |||
TMPY-02196 | VAPB Protein, Human, Recombinant (His) | Human | E. coli |
Vesicle-associated membrane protein-associated protein B / C, also known as VAMP-B/VAMP-C, VAMP-associated protein B/C, VAP-B/VAP-C and VAPB, is a single-pass type IV membrane protein that belongs to the VAMP-associated ... | |||
TMPH-03181 | LaaA Protein, Pseudomonas azotoformans, Recombinant (His & Myc & SUMO) | Pseudomonas azotoformans | E. coli |
Hydrolyzes L-prolinamide, L-proline-p-nitroanilide, L-alaninamide, L-methioninamide, piperidine-2-carboxamide and piperazine-2-carboxamide. Has a much lower activity towards piperazine-2-tert-butylcarboxamide. Does not h... | |||
TMPK-01051 | BLOC1S2 Protein, Human, Recombinant | Human | E. coli |
BLOC1S2 (Biogenesis of lysosome-related organelles complex-1 subunit 2) protein is widely expressed in normal tissue as well as in malignant tumors with a tendency towards lower expression levels in certain subtypes of t... | |||
TMPK-01268 | Complement C2 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Single nucleotide polymorphism (SNP) of complement component 2 (C2) has been found to be significantly associated with hepatocellular carcinoma (HCC). Significantly lower C2 expression was found at HCC compared to health... | |||
TMPJ-00273 | IGSF11 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Immunoglobulin superfamily member 11(IGSF11) is abundantly expressed in testis and ovary and to a lower extent in brain, kidney and skeletal muscle.IGSF11 functions as a cell adhesion molecule through homophilic interact... | |||
TMPJ-00691 | ZG16 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Zymogen Granule Membrane Protein 16 (ZG16) belongs to the jacalin lectin family. ZG16 is highly expressed in liver and is detected at lower levels in colon, ileum and jejunum. ZG16 may play a role in protein trafficking.... | |||
TMPY-04463 | CDKL2 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Cyclin-dependent kinase-like 2 (Cdkl2) is a member of cdc2-related serine / threonine protein kinase family and it is found expressed in various brain regions, including the cerebral cortex, entorinal cortex, hippocampus... | |||
TMPY-05186 | LILRB5/CD85c Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 Cells |
A genetic variant in LILRB5 (leukocyte immunoglobulin-like receptor subfamily-B) (rs12975366: T > C: Asp247Gly) has been reported to be associated with lower creatine phosphokinase (CK) and lactate dehydrogenase (LDH) le... | |||
TMPH-00877 | ACSS1 Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids. Acetate is the preferred substrate. Can also utilize propionate with a much lower affinity. Provides acetyl-CoA that is utilized mainly for oxidation un... | |||
TMPH-01361 | GAL3ST3 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Transfers a sulfate to position 3 of non-reducing beta-galactosyl residues in N-glycans and core2-branched O-glycans. Has high activity towards Gal-beta-1,4-GlcNAc, Gal-beta-1,4(Fuc-alpha-1,3)GlcNAc and lower activity to... | |||
TMPY-06273 | LILRB5/CD85c Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
A genetic variant in LILRB5 (leukocyte immunoglobulin-like receptor subfamily-B) (rs12975366: T > C: Asp247Gly) has been reported to be associated with lower creatine phosphokinase (CK) and lactate dehydrogenase (LDH) le... | |||
TMPH-03568 | Phospholipase C Protein, S. aureus, Recombinant (His) | Staphylococcus aureus | P. pastoris (Yeast) |
Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydr... | |||
TMPH-03182 | DTE Protein, Pseudomonas cichorii, Recombinant (His & Myc) | Pseudomonas cichorii | E. coli |
Catalyzes the epimerization of various ketoses at the C(3) position. It is able to interconvert D-tagatose and D-ribulose to D-sorbose and D-xylulose, respectively. The enzyme is also able to accept other ketopentoses su... | |||
TMPY-06179 | IdeS Protein, Streptococcus pyogenes, Recombinant (His & GST) | Streptococcus pyogenes | E. coli |
IdeS (IgG-degrading enzyme of Streptococcus pyogenes) is a secreted cysteine endopeptidase from the human pathogen S. pyogenes with an extraordinarily high degree of substrate specificity, catalyzing a single proteolytic... | |||
TMPH-00876 | ACSS1 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids. Acetate is the preferred substrate. Can also utilize propionate with a much lower affinity. Provides acetyl-CoA that is utilized mainly for oxidation un... | |||
TMPJ-00974 | XCL1 Protein, Human, Recombinant (hFc & His) | Human | HEK293 Cells |
Lymphotactin is a secreted protein which belongs to the intercrine gamma family. It is also a member of the XC chemokine family. XCL1 is found in spleen with highest level, lower in peripheral leukocytes and very low lev... | |||
TMPJ-00708 | CST7 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Mouse Cystatin F belongs to cystatin superfamily, which encompasses proteins that contain multiple cystatin-like sequences. It has been shown that Cystatin F is selectively expressed by hematopoietic cells and may be a b... | |||
TMPJ-01262 | UPRT Protein, Human, Recombinant (His) | Human | E. coli |
UPRT is a cytoplasmic enzyme which belongs to the UPRTase family. UPRT is highly expressed in leukocytes, liver, spleen and thymus, with lower expression in brain, lung and skeletal muscle. UPRTcatalyzes the conversion o... | |||
TMPK-01057 | CLEC9A Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
CLEC9A expression was significantly higher in psoriatic skin compared with healthy donor. In psoriatic skin and PsA ST, CLEC9A() cells were in close proximity to TUNEL() cells. SF CLEC9A levels were significantly lower c... | |||
TMPY-06023 | IdeS Protein, Streptococcus pyogenes, Recombinant (His) | Streptococcus pyogenes | E. coli |
IdeS (IgG-degrading enzyme of Streptococcus pyogenes) is a secreted cysteine endopeptidase from the human pathogen S. pyogenes with an extraordinarily high degree of substrate specificity, catalyzing a single proteolytic... | |||
TMPJ-01380 | ST6GalNAc2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Alpha-N-Acetylgalactosaminide α-2,6-Sialyltransferase 2 (ST6GALNAC2) belongs to the glycosyltransferase 29 family that adds sialic acids to the non-reducing ends of glycoconjugates. At the cell surface, these modificatio... | |||
TMPY-01479 | SPG3A Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
Atlastin-1, also known as Spastic paraplegia 3 protein A, Guanine nucleotide-binding protein 3, GTP-binding protein 3, GBP3, ATL1 and SPG3A, is a multi-pass membrane protein which belongs to theGBP family and atlastin... | |||
TMPH-02740 | IL-31R alpha Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Mediates IL31-induced itch, probably in a manner dependent on cation ch... | |||
TMPY-03182 | PLRP2 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Galactolipase, also known as PNLIPRP2, is a lipase with broad substrate specificity. It can hydrolyze both phospholipids and galactolipids. Galactolipase acts preferentially on monoglycerides, phospholipids and galactoli... | |||
TMPJ-01307 | PACSIN1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Protein Kinase C and Casein Kinase Substrate in Neurons Protein 1 (PACSIN1) belongs to the PACSIN family. PACSIN1 contains one FCH domain and one SH3 domain. PACSIN1 is highly expressed in the brain and at lower leves in... | |||
TMPH-00433 | Ex-FABP Protein, Coturnix coturnix japonica, Recombinant (His & Myc) | Coturnix coturnix japonica | E. coli |
Siderocalin-like lipocalin tightly binding a variety of bacterial ferric siderophores, also binds long-chain unsaturated fatty acids such as linoleic acid, oleic acid, arachidonic acid and, with a lower affinity, long ch... | |||
TMPK-00243 | IL-13Ra2 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Two type 1 membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha,... | |||
TMPK-00941 | TFF1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Breast cancer (BC) is the most common cancer in women and the second leading cause of their cancer death. Establishing an accurate BC prognosis is very difficult because of its heterogeneity. Elevated TFF1 levels in seru... | |||
TMPH-02331 | GLRA1 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine. Channel opening is also triggered by taurine and beta-alanine. Channel characteristics depend on the subunit co... | |||
TMPJ-00902 | Kell Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Kell blood group glycoprotein (KEL) is a single-pass type II membrane protein which belongs to the peptidase M13 family. It is expressed in Expressed at high levels in erythrocytes and testis, and, at lower levels, in sk... | |||
TMPJ-01258 | RNASE6 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Ribonuclease K6 (RNASE6) is a secreted protein that belongs to the pancreatic ribonuclease family. Human RNASE6 is synthesized as a 150 amino acid precursor that contains a 23 amino acid signal sequence, and a 127 amino ... | |||
TMPJ-01257 | PMM1 Protein, Human, Recombinant (His) | Human | E. coli |
Phosphomannomutase 1 (PMM1) blongs to the eukaryotic PMM family. Phosphomannomutase 1 can catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. G... | |||
TMPH-02312 | Wilms tumor protein/WT1 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Transcription factor that plays an important role in cellular development and cell survival. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'. Regulates the expression of numerous target genes, including EPO.... | |||
TMPJ-01268 | ERP27 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Endoplasmic reticulum resident protein 27, also known as ER protein 27, C12orf46 and ERP27, is an endoplasmic reticulum luminal protein which is a member of the protein disulfide isomerase family. ERP27 contains one thio... | |||
TMPH-01978 | SFTPA1 Protein, Human, Recombinant (B2M & His & Myc) | Human | E. coli |
In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. Enh... | |||
TMPJ-00086 | CT-1 Protein, Human, Recombinant (His) | Human | E. coli |
Cardiotrophin-1, also known as CT-1 and CTF1, is a member of the IL-6 superfamily. It is a sreted cytokine that is expressed in heart, skeletal muscle, prostate and ovary, and to lower levels in lung, kidney, pancreas, t... | |||
TMPJ-00297 | SHPK Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Sedoheptulokinase (SHPK) belongs to the FGGY kinase family, and is mainly located in cytoplasm. SHPK is strongly expressed in liver, kidney and pancreas. It is expressed at lower levels in placenta and heart, and very we... | |||
TMPK-00244 | IL-13RA2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Two type 1 membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha,... | |||
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