|
T3041 |
ALK inhibitor 2
|
|
FAK
,
ALK
|
|
ALK inhibitor 2 is a new-type and selective inhibitor for the ALK kinase. |
|
T10285 |
ALK inhibitor 1
|
|
FAK
,
IGF-1R
,
ALK
|
|
ALK inhibitor 1 is a selective ALK kinase inhibitor. |
|
T23483 |
U 99194 maleate
|
U-99194A maleate,U-99194 maleate salt,U-99194 maleate |
Dopamine Receptor
|
|
U 99194 maleate (U-99194A maleate) is a D3 antagonist and increases social behaviors of isolation-induced aggressive male mice. |
|
T22520 |
5-Carboxamidotryptamine maleate
|
5-CT maleate |
5-HT Receptor
|
|
5-Carboxamidotryptamine maleate (5-CT maleate) (5-CT maleate) is a receptor agonist with antihypertensive and glucose-raising effects. |
|
T67385 |
Neratinib maleate
|
HKI-272 maleate |
EGFR
,
HER
|
|
Neratinib maleate (HKI-272 maleate) is an irreversible, orally active and highly selective inhibitor of HER2 and EGFR with IC50 values of 59 nM and 92 nM, respectively.Neratinib maleate has antitumor activity and can be ... |
|
T21556 |
Hydroxytacrine maleate
|
Velnacrine maleate,HP 029 maleate |
AChE
|
|
Hydroxytacrine maleate (Velnacrine maleate) is a cholinesterase (cholinesterase) inhibitor that enhances memory in rodents and may be used in the study of Alzheimer's dementia of the Alzheimer type (SDAT). |
|
T3435 |
Vicriviroc maleate
|
SCH-D (maleate),SCH-417690 (maleate) |
HIV Protease
,
CCR
|
|
Vicriviroc maleate (SCH-417690 (maleate))(Sch-417690) is a piperazine-based CCR5 receptor antagonist with activity against human immunodeficiency virus. The IC50 value is 0.91 nM in clinical development for the treatment... |
|
T0368 |
Cinepazide maleate
|
MD-67350,Vasodistal,Brendil |
Calcium Channel
|
|
Cinepazide maleate (MD-67350), a maleate salt form of cinepazide, is a vasodilator. |
|
T4422 |
Edonerpic maleate
|
T-817MA,T-817 maleate |
Beta Amyloid
|
|
Edonerpic maleate (T-817 maleate) is a neurotrophic agent which can inhibit amyloid-β peptides (Aβ). |
|
T6914 |
Oclacitinib maleate
|
PF-03394197 maleate,PF-03394197 |
Tyrosine Kinases
,
JAK
|
|
Oclacitinib maleate (PF-03394197 maleate) is a novel inhibitor of JAK family members with IC50 ranging from 10 to 99 nM and JAK1-dependent cytokines with IC50 ranging from 36 to 249 nM, which did not inhibit a panel of 3... |
|
T83975 |
Fenclozine Maleate
|
S 1429 |
Histamine Receptor
|
|
Fenclozine Maleate (S 1429) is a potential histamine H1 receptor antagonist , which can be used to study fever, inflammation and pain. |
|
T1197 |
Trimebutine maleate
|
Debridat,Polibutin |
Calcium Channel
,
Opioid Receptor
|
|
Trimebutine maleate (Polibutin) is a weak mu-opioid agonist and has antimuscarinic effects. Trimebutine is an agonist of peripheral mu, delta, and kappa opiate receptors served as a spasmolytic drug for therapy of both c... |
|
T6486 |
Enalapril Maleate
|
MK-421 Maleate,Renitec Maleate,Glioten Maleate,MK-421 (maleate),Vasotec Maleate |
RAAS
|
|
Enalapril Maleate (MK-421 Maleate), an angiotensin-converting enzyme (ACE) inhibitor, is utilized in the treatment of hypertension, chronic heart failure , and diabetic nephropathy. |
|
T1951 |
Asenapine Maleate
|
Org 5222 maleate,Org 5222 |
5-HT Receptor
|
|
Asenapine Maleate (Org 5222 maleate) is a second generation (atypical) antipsychotic agent that is taken sublingually and used in the treatment of schizophrenia and manic or mixed episodes associated with bipolar 1 disor... |
|
T1622 |
Rosiglitazone maleate
|
BRL 49653C,BRL 49653 |
Ferroptosis
,
TRP/TRPV Channel
,
PPAR
,
Autophagy
|
|
Rosiglitazone maleate (BRL 49653) is the maleate salt of rosiglitazone, an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity. |
|
T1077 |
Fluvoxamine maleate
|
MK-264,DU-23000 (maleate) |
5-HT Receptor
,
Serotonin Transporter
|
|
Fluvoxamine maleate (DU-23000 (maleate)) is a selective serotonin reuptake inhibitor that is used in the treatment of depression and a variety of anxiety disorders. |
|
T2222 |
Carbinoxamine Maleate Salt
|
Lergefin,CarbinoxaMine Maleate |
Histamine Receptor
|
|
Carbinoxamine Maleate Salt (Lergefin) is an ethanolamine class of H1 antihistamines with mild antimuscarinic and sedative properties. |
|
T0236 |
Azatadine dimaleate
|
SCH10649,Azatadine Maleate |
5-HT Receptor
,
AChR
,
Histamine Receptor
|
|
Azatadine dimaleate (SCH10649) is an inhibitor for histamine（IC50=6.5 nM） and cholinergic（IC50=10 nM）. |
|
T10232 |
Acetophenazine dimaleate
|
|
Dopamine Receptor
|
|
Acetophenazine dimaleate is an antipsychotic agent, effective in anxious depression. Acetophenazine dimaleate primarily targets the dopamine D2 receptor. |
|
T9306 |
EST64454 Maleic acid salt
|
|
Others
|
|
EST64454 Maleic acid salt is the maleic acid salt form of EST64454.EST64454 is a highly soluble σ1 receptor antagonist clinical candidate for the treatment of pain. |
|
T1239 |
Indacaterol maleate
|
QAB149 |
Adrenergic Receptor
|
|
Indacaterol maleate (QAB149) is an ultra-long-acting β-adrenoceptor agonist. |
|
T2004 |
Ciproxifan maleate
|
FUB 359 maleate,FUB 359 |
Histamine Receptor
|
|
Ciproxifan maleate (FUB 359)(FUB-359 maleate) is a highly potent and selective histamin H3-receptor antagonist with IC50 of 9.2 nM, with low apparent affinity at other receptor subtypes. |
|
T3721 |
Avitinib maleate
|
|
EGFR
|
|
Avitinib maleate is a pyrrolopyrimidine-based irreversible epidermal growth factor receptor (EGFR) inhibitor. |
|
T6513 |
Bisindolylmaleimide I
|
GF109203X,Go 6850 |
PDGFR
,
PKC
|
|
Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor with a Ki of 14 nM. |
|
T23212 |
Quipazine dimaleate
|
|
5-HT Receptor
|
|
Quipazine dimaleate is a selective 5-HT3 agonist. |
|
T17324 |
11-Maleimidoundecanoic acid
|
|
Others
,
PROTAC Linker
|
|
11-Maleimidoundecanoic acid is an alkyl chain-based PROTAC linker that can be used in PROTAC synthesis. |
|
T4980 |
Betrixaban maleate
|
|
Factor Xa
|
|
Betrixaban maleate is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa. |
|
T6072 |
BGT226 maleate
|
BGT226,NVP-BGT226 (maleate),NVP-BGT226 |
Apoptosis
,
PI3K
,
mTOR
,
Autophagy
|
|
BGT226 maleate (NVP-BGT226) is a class I PI3K/mTOR inhibitor for PI3Kα/β/γ (IC50: 4/63/38 nM) . |
|
T18991 |
Fluorescein-5-maleimide
|
N-(5-Fluoresceinyl)maleimide |
Others
|
|
Fluorescein-5-maleimide (N-(5-Fluoresceinyl)maleimide) is a fluorescent thiol-reactive dye (excitation: 494 nm, emission: 519 nm). |
|
T3088 |
N-Ethylmaleimide
|
1-Ethyl-1H-pyrrole-2,5-dione,Ethylmaleimide,NEM |
Cysteine Protease
,
DUB
|
|
N-Ethylmaleimide (NEM) is a sulfhydryl reagent that is widely used in experimental biochemical studies. |
|
T12594 |
Pyrotinib dimaleate
|
SHR-1258 dimaleate |
EGFR
,
HER
|
|
Pyrotinib dimaleate (SHR-1258 dimaleate) is a potent and selective dual inhibitor of EGFR/HER2 with IC50s of 13 and 38 nM, respectively. |
|
T22899 |
L-693,403 maleate
|
|
Others
|
|
L-693,403 maleate has analgesic activity. |
|
T12266L |
Ilginatinib maleate
|
NS-018 maleate |
Tyrosine Kinases
,
JAK
|
|
Ilginatinib maleate (NS-018 maleate) is a highly active and orally bioavailable inhibitor of JAK2. |
|
T7659 |
Bisindolylmaleimide IV
|
|
Others
,
PKC
|
|
Bisindolylmaleimide IV is a protein kinase C (PKC) cell permeable inhibitor( IC50 : 0.10 - 0.55 μM) |
|
T22842 |
HTMT dimaleate
|
Histamine Trifluoromethyl Toluidide Dimaleate |
Histamine Receptor
|
|
HTMT dimaleate (Histamine Trifluoromethyl Toluidide Dimaleate) is an H1 and H2 receptor agonist. |
|
T5047 |
PD-168077 maleate
|
|
Dopamine Receptor
|
|
PD-168077 maleate is a selective agonist of dopamine D4 receptor(Ki : 9 nM) |
|
T0385 |
Prochlorperazine Maleate
|
Prochlorperazin,Capazine,Prochlorperazine dimaleate salt,Stemetil,Compazine |
Dopamine Receptor
|
|
Prochlorperazine Maleate (Capazine) is a phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS. |
|
T21472 |
Dimethindene maleate
|
UNII-6LL60J9E0O,SU 6518,SU-6518 |
Histamine Receptor
|
|
Dimethindene maleate (SU 6518) is a histamine H1 antagonist and can be used in studies about the treatment of hypersensitivity reactions, pruritus and rhinitis. |
|
T1553 |
Chlorpheniramine maleate
|
NCI-C55265,Chlorphenamine maleate |
Histamine Receptor
|
|
Chlorpheniramine maleate (NCI-C55265) is a histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. |
|
T84299 |
BHQ3 Maleimide
|
|
|
|
BHQ3 Maleimide is a fluorescent probe that eliminates background fluorescence and can be used for protein labeling, nucleic acid labeling and cellular imaging. |
|
T25828 |
Monatepil maleate
|
AJ2615 maleate,AJ-2615 maleate,AJ 2615 maleate |
Calcium Channel
,
Adrenergic Receptor
,
Acyltransferase
|
|
Monatepil maleate (AJ-2615 maleate) is an orally active Ca2+-channel and α1-adrenoceptor antagonist and non-competitive heparanoyl-coenzyme A:cholesterol acyltransferase (ACAT) inhibitor with antihypertensive activity.Mo... |
|
T21480 |
Diethylmaleate
|
Maleic acid, diethyl ester,DIETHYL MALEATE |
NF-κB
|
|
Diethylmaleate (Maleic acid, diethyl ester) is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB. |
|
T6352 |
(-)-Dizocilpine maleate
|
C13737,(-)-MK 801 (Maleate),(-)-MK 801 Maleate |
NMDAR
,
iGluR
|
|
(-)-Dizocilpine maleate ((-)-MK 801 (Maleate)) is a potent, selective and non-competitive NMDA receptor antagonist with Kd of 37.2 nM in rat brain membranes. |
|
T0785 |
Dexchlorpheniramine Maleate
|
S-(+)-Chlorpheniramine maleate salt |
Dopamine Receptor
,
5-HT Receptor
,
Norepinephrine
,
Histamine Receptor
|
|
Dexchlorpheniramine Maleate (S-(+)-Chlorpheniramine maleate salt) is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria. It is the pharmacologically active d... |
|
T12489L |
Pimethixene maleate
|
Pimetixene maleate |
Dopamine Receptor
,
5-HT Receptor
,
AChR
,
Histamine Receptor
|
|
Pimethixene maleate (Pimetixene maleate) is a potent 5-HT2B receptor antagonist with sedative and antitussive activity.Pimethixene maleate inhibits 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as we... |
|
T21263 |
Amlodipine maleate
|
Amlodipine (+-)-form maleate,Amvaz |
Calcium Channel
|
|
Amlodipine maleate (Amvaz) is an orally active dihydropyridine calcium channel blocker that inhibits calcium inward flow by blocking voltage-dependent L-type calcium channels.Amlodipine maleate is used in the study of hy... |
|
T7790 |
Bisindolylmaleimide V
|
|
PKC
,
S6 Kinase
|
|
Bisindolylmaleimide V, a bisindolylmaleimide derivative, is an inactive of a kinase inhibitor. |
|
T20506 |
Maleuric acid
|
N-Carbamoylmaleamic acid,AI3 32778,AI3-32778,AI332778 |
Others
|
|
Maleuric acid (N-Carbamoylmaleamic acid) is anti-mitotic and can be used in biological research in conjunction with radioautography.Maleuric acid is used to improve the growth and fertility of plants and animals as well ... |
|
T22879 |
JNJ 10191584 maleate
|
JNJ 10191584 maleate salt,VUF6002 maleate |
Histamine Receptor
|
|
JNJ 10191584 maleate (VUF6002 maleate) is an orally active and selective antagonist of H4 receptor (Ki = 26 nM). JNJ 10191584 maleate inhibits chemotaxis of eosinophils and mast cells (IC50 = 530 nM and 138 nM). |
|
T19957 |
Bismaleimide
|
XU 292A,XU-292A,XU292A |
Others
|
|
Bismaleimide (XU 292A) has heat resistance, oxidation resistance and radiation resistance, and can be used to prepare electrical insulation materials, wear-resistant materials, reinforced plastic additives, grinding whee... |
