| T19117 |
3-Deoxyglucosone
|
3-Deoxy-D-glucosone,2-keto-3-Deoxyglucose |
GPX
,
Glucagon Receptor
|
|
3-Deoxyglucosone(3-Deoxy-D-glucosone) is synthesized by the intermediate pathway of the melad and polyol reactions.3-Deoxyglucosone reacts rapidly with protein amino groups to form advanced glycosylated end proteins (AGE... |
| TN2430 |
Glucodigifucoside
|
|
|
|
Glucodigifucoside, a cardiac glycoside that can be isolated from digitalis seeds, is specifically cytotoxic to human renal adenocarcinoma cells. |
| T19231 |
Cellulase
|
|
Others
|
|
Cellulase is an enzyme that catalyzes the hydrolysis of certain linkages in cellulose. |
| TN1818 |
Kaempferol 3-O-β-D-glucuronide
|
Kaempferol-3-O-glucuronide,Kaempferol-3-beta-O-glucuronide,Kaempferol-3-glucuronide |
IL Receptor
|
|
Kaempferol 3-O-β-D-glucuronide (Kaempferol-3-beta-O-glucuronide)e has antioxidant activity. Flavonoid glucuronides can be deconjugated by microsomal α²-glucuronidase from various human cells. |
| T3816 |
Velutin
|
|
NF-κB
,
HIF/HIF Prolyl-Hydroxylase
|
|
Velutin shows the strongest inhibitory effect in NF-κB activation and exhibits the greatest effects in blocking the degradation of inhibitor of NF-κB as well as in inhibiting mitogen-activated protein kinase p38 and JNK ... |
| TN1621 |
Eriodictyol-7-O-glucoside
|
|
Nrf2
|
|
Eriodictyol-7-O-glucoside is an Nrf2 activator conferring protection against Cisplatin-induced toxicity. Eriodictyol-7-O-glucoside is a flavonoid and a free radical scavenger with antioxidant activity in pistachio skin. |
| TN1107 |
Lupeol palmitate
|
|
Others
|
|
Lupeol palmitate is a naturally occurring compound that can be extracted from Ligularia songarica and has antiulcer activity and gastrointestinal protection. |
| T19357 |
Hyaluronidase
|
Hyaluronate 4-glycanohydrolase,Hyaluronoglucosaminidase |
Others
|
|
Hyaluronidase (Hyaluronate 4-glycanohydrolase), a naturally occurring enzyme, depolymerizes hyaluronic acid through glycosidic bond cleavage and is utilized in ophthalmic surgery. |
| T5S0803 |
Columbamine
|
Columbamin,Dehydroisocorypalmine |
Others
|
|
Columbamine (Columbamin) shows strong activity with IC5 48.1 μM.Columbamine exerts anti-proliferative and anti-vasculogenic effects on metastatic human osteosarcoma U2OS cells with low toxicity. |
| T4884 |
Alpha-D-glucose
|
α-D-Glucose,alpha-Glucose,α-Dextrose |
Others
,
Endogenous Metabolite
|
|
alpha-D-glucose (α-Dextrose) is a primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutri... |
| T8226 |
Cue-lure
|
Q-lure,Pherocon (4-(4-Acetoxyphenyl)-2-butanone) |
Others
|
|
Cue-lure (Pherocon (4-(4-Acetoxyphenyl)-2-butanone)) is a standard melon fly attractant |
| T8163 |
Glucovanillin
|
Vanillin 4-O-β-D-Glucoside |
Others
|
|
Glucovanillin (Vanillin 4-O-β-D-Glucoside) belongs to the class of organic compounds known as phenolic glycosides. |
| TN1880 |
Lucidenic acid B
|
Lucidenicacid B |
Apoptosis
,
Caspase
|
|
Lucidenic acid B (Lucidenicacid B), a natural compound extracted from Ganoderma lucidum, induces activation of caspase-9 and caspase-3 and cleavage of PARP, which can induce apoptosis in human leukemia cells through mito... |
| T8075 |
1,3-Dimethyluric acid
|
|
Endogenous Metabolite
|
|
1,3-Dimethyluric acid is a product of theophylline metabolism in man. It is one of the purine components in urinary calculi. |
| T2841 |
Plumbagin
|
Plumbagone,Plumbagine,Plumbaein,2-Methyljuglone |
ROS
|
|
Plumbagin (Plumbaein) is a yellow dye, formally derived from naphthoquinone. It is named after the plant genus Plumbago, from which it was originally isolated. It is also commonly found in the carnivorous plant genera Dr... |
| T2771 |
Orcinol glucoside
|
Sakakin |
Antioxidant
|
|
Orcinol glucoside (Sakakin) (OG), an active constituent isolated from the rhizomes of Curculigo orchioides Gaertn, shows potent antioxidative and anxiolytic activities without sedative effects. |
| T3882 |
4”-O-Glucosylvitexin
|
glucosylvitexin |
Thrombopoietin Receptor
|
|
4”-O-Glucosylvitexin (glucosylvitexin) inhibits TPO activity. |
| T1388 |
Fluconazole
|
UK-49858 |
Antibiotic
,
Antifection
,
Antifungal
|
|
Fluconazole (UK-49858) is a triazole antifungal agent that is used to treat oropharyngeal candidiasis and cryptococcal meningitis in AIDS. |
| T20198 |
Potassium gluconate
|
Kalium-beta,Kalium Gluconate,Kaon elixir,Kaon,Potassium D-gluconate,HSDB 3165,K-Iao |
Endogenous Metabolite
,
Antifungal
|
|
Potassium gluconate (Potassium D-gluconate) is an oxidizing carboxylic acid with oral activity and chelating properties with bactericidal activity. |
| TN6774 |
Emodin 6-O-β-D-glucoside
|
Glucoemodin |
Others
|
|
Emodin 6-O-β-D-glucoside (Glucoemodin) can protect barrier integrity and inhibit HMGB1-mediated inflammatory responses, which suggests a potential use as a therapy for sepsis or septic shock. Emodin 6-O-beta-D-glucoside ... |
| TN6552 |
5,7-Dimethoxyluteolin
|
|
Dopamine Receptor
|
|
5,7-Dimethoxyluteolin is a natural product from Hovenia acerba. 5,7-Dimethoxyluteolin is a dopamine transporter (DAT) activator with an EC50 of 3.417 μM. |
| TN2802 |
20-O-Glucoginsenoside Rf
|
|
Others
|
|
20-O-Glucoginsenoside Rf is a natural product extracted from Panax ginseng C. A. Mey. |
| T1391 |
4-Methylumbelliferone
|
Hymecromone,4-MU |
Others
|
|
4-Methylumbelliferone (Hymecromone) is a coumarin derivative possessing properties as a spasmolytic, choleretic and light-protective agent. It is also used in ANALYTICAL CHEMISTRY TECHNIQUES for the determination of NITR... |
| TN2277 |
Torachrysone-8-O-b-D-glucoside
|
Torachrysone 8-O-glucoside |
Antifection
|
|
Torachrysone-8-O-b-D-glucoside shows alpha-glucosidase inhibitory activities, it may be used for the management of type 2 diabetes. |
| TN6782 |
Oroxylin A 7-O-β-d-glucuronide
|
|
Others
|
|
Oroxylin A 7-O-β-d-glucuronide was a new alkaloid which found in the bulbs of Lycoris radiata. |
| T3415 |
Secoisolariciresinol diglucoside
|
LGM2605 |
ROS
|
|
Secoisolariciresinol diglucoside (LGM2605) was cytoprotective in an in vitro model of iron overload-induced redox-inflammatory damage. Secoisolariciresinol diglucoside (25 mg/kg b.w.) exerts the antihyperglycemic effect ... |
| T6S0535 |
Pinoresinol diglucoside
|
Pinoresinol Diglucopyranoside |
Glucosidase
|
|
1. Pinoresinol diglucoside (Pinoresinol Diglucopyranoside) is a putative α-glucosidase inhibiting compound. 2. Pinoresinol diglucoside is a important antihypertensive compound. |
| T13818 |
Phytohemagglutinin
|
PHA-M |
Apoptosis
|
|
Phytohemagglutinin (PHA-M) is a lectin, isolated from the red kidney bean , induces apoptosis via increasing proapoptotic protein Bax and activating caspases-3. Anti-tumor activity |
| TN1892 |
Lusianthridin
|
|
Others
,
c-Myc
|
|
Lusianthridin is a natural product from Dendrobium venustum. Lusianthridin exhibits anti-migratory property at nontoxic concentrations. Lusianthridin enhances c-Myc degradation through the inhibition of Src-STAT3 signali... |
| T4743 |
Uridine 5′-diphosphoglucose disodium salt
|
UDP-Glucose sodium salt,UDPG sodium salt,UDP-α-D-Glucose sodium salt,Uridine 5'-diphosphoglucose disodium sal |
Endogenous Metabolite
,
P2Y Receptor
|
|
Uridine 5′-diphosphoglucose disodium salt (UDP-Glucose sodium salt) is an endogenous nucleotide sugar involved in glycosyltransferase reactions in Metabolism. It is an agonist of the P2Y14 receptor (EC50 = 0.35 μM). It c... |
| TN7092 |
Lugrandoside
|
|
Others
|
|
Lugrandoside is a novel phenylpropanoid glycoside, lugrandoside, has been isolated from the caulinary leaves of Digitalis Lutea L. and Difitalis Grandiflora Miller. |
| T4794 |
Glutaric acid
|
|
Endogenous Metabolite
|
|
Glutaric acid is a simple five-carbon linear dicarboxylic acid. Glutaric acid is naturally produced in the body during the metabolism of some amino acids, including lysine and tryptophan |
| T19792 |
1,3,7-Trimethyluric acid
|
|
Others
|
|
1,3,7-Trimethyluric acid is a purine alkaloid that occurs as a minor metabolite of caffeine in humans. As an antioxidant, it has shown an ability to scavenge hydroxyl radicals as well as protective potential against lipi... |
| T67708 |
Thiolutin
|
Acetopyrrothin |
Antibacterial
,
Antibiotic
|
|
Thiolutin (Acetopyrrothin) is an inhibitor of endothelial cell adhesion and produced by Streptomyces. Thiolutin shows antibiotic and anti-angiogenic properties. Thiolutin induces the phosphorylation of Hsp27 rapidly. |
| TQ0203 |
Tafluprost
|
MK2452,AFP-168 |
Prostaglandin Receptor
|
|
Tafluprost, a prostaglandin analog, is the selective agonist of fluoroprostaglandin (FP) receptor PGF2α. |
| T5741 |
Pseudolaric acid B β-D-glucoside
|
Pseudolaric acid B-glucopyranoside |
Others
|
|
Pseudolaric acid B β-D-glucoside (Pseudolaric acid B-glucopyranoside) is a natural product from Pseudolarix amabilis. |
| TN6734 |
Quercetin-3-O-D-glucosyl]-(1-2)-L-rhamnoside
|
Quercetin 3-O-beta-D-glucosyl-(1->2)-rhamnoside |
Others
|
|
Quercetin-3-O-D-glucosyl]-(1-2)-L-rhamnoside (Quercetin 3-O-beta-D-glucosyl-(1->2)-rhamnoside) is main antioxidant of Shuxuening, an herbal medicines injection. |
| T5708 |
LUPENONE
|
|
Phosphatase
,
Parasite
|
|
Lupenone is a natural product isolated from Rhizoma Musae and has good anti-diabetic activity,and has anti-inflammatory activity.lupenone were potent PTP1B inhibitors with IC50 values of 15.11±1.23μM. |
| TN2401 |
Ethyl glucoside
|
β-D-Glucopyranoside, ethyl,Ethyl D-glucoside |
Others
|
|
Ethyl glucoside (β-D-Glucopyranoside, ethyl), a shale inhibitor for water-based drilling fluids, is a versatile initiator of enzyme-catalyzed regioselective lactone ring-opening polymerization and is a natural compound f... |
| T6742 |
2-Deoxy-D-glucose
|
2-Deoxy-D-arabino-hexose,2-deoxyglucose,D-Arabino-2-deoxyhexose,Ba 2758,NSC 15193,2-DG |
Apoptosis
,
Hexokinase
,
HSV
|
|
2-Deoxy-D-glucose (2-DG) is an analog of glucose, an inhibitor of glycolysis. 2-Deoxy-D-glucose has antiviral activity, as well as inhibitory cell proliferation and apoptosis-inducing activity. |
| T0416 |
Gluconate sodium
|
Sodium D-gluconate,Sodium gluconate,D-Gluconic acid sodium salt,D-Gluconate sodium salt |
Others
,
Endogenous Metabolite
|
|
Gluconate sodium (Sodium D-gluconate) is the sodium salt of gluconic acid with a chelating property. |
| T2941 |
Glucosamine hydrochloride
|
Chitosamine hydrochloride,2-Amino-2-deoxy-glucose HCl,Chitosamine HCl,D-(+)-Glucosamine hydrochloride |
Reactive Oxygen Species
,
HIF/HIF Prolyl-Hydroxylase
,
Endogenous Metabolite
,
Autophagy
|
|
Glucosamine hydrochloride (Chitosamine hydrochloride) is commonly used as a treatment for osteoarthritis, although its acceptance as a medical therapy varies. |
| T6871 |
L-Glutamic acid monosodium salt
|
Monosodium glutamate,Glutacyl,Glutavene,Ajinomoto,MSG |
Apoptosis
,
Ferroptosis
,
GluR
,
iGluR
|
|
L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor. |
| T19262 |
D-Glucose 6-phosphate disodium salt
|
D-Glucose 6-phosphate disodium salt |
Endogenous Metabolite
|
|
D-Glucose 6-phosphate disodium salt is a compound widely present in biological systems. It is a molecule formed when glucose undergoes phosphorylation at the 6th carbon. This compound participates in various metabolic re... |
| TN1891 |
Lupiwighteone
|
|
Apoptosis
,
BCL
,
PARP
,
Caspase
|
|
Lupiwighteone has anti-angiogenesis potential, it also has anticancer and cancer preventive effects on SH-SY5Y cells. |
| TN1414 |
Aurantio-obtusin β-D-glucoside
|
Aurantio-obtusin beta-D-glucoside |
Others
|
|
Aurantio-obtusin β-D-glucoside (Aurantio-obtusin beta-D-glucoside) is a natural product originated from the enzymatic cleavage of its glucoside glucoaurantio-obtusin. |
| T12016 |
Methyl L-pyroglutamate
|
L-Pyroglutamic acid methyl ester,(S)-Methyl 5-oxopyrrolidine-2-carboxylate |
Others
|
|
Methyl L-pyroglutamate (L-Pyroglutamic acid methyl ester) shows anti-inflammatory activity. Methyl L-pyroglutamate is isolated from Portulaca oleracea L.. |
| T7464 |
3,3-Dimethylglutaric acid
|
3,3-Dimethylpentanedioate |
Others
,
Endogenous Metabolite
|
|
3,3-Dimethylglutaric acid (3,3-Dimethylpentanedioate) is a compound found in human urine. |
| T2S1682 |
Pinocembrin 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-β-D-glucoside
|
Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-beta-D-glucose,pinocembrin-7-o-3-o-galloyl-4-6-hexahydroxydiphenoyl-beta-d-glucoside |
Amylase
|
|
Pinocembrin 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-β-D-glucoside can moderately inhibit α-amylase activity, with the IC50 value of 0.03 umol/ml. |
| T12039 |
Miglustat
|
N-Butyldeoxynojirimycin,OGT918,NB-DNJ |
Others
|
|
Miglustat (NB-DNJ) is an alkylated product of imino sugar deoxynojirimycin.It is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1). |
