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Search Results for " VEGFR-3 "

ターゲット

56

阻害剤

3

天然化合物

66

リコンビナントタンパク質

2

ライブラリー

カタログ番号 製品名 別名 ターゲット
T72924 VEGFR-3-IN-1 VEGFR
VEGFR-3-IN-1 is a novel potent and selective VEGFR3 inhibitor with an IC50 of 110.4 nM.VEGFR-3-IN-1 possesses antitumor activity, inactivates the VEGFR3 signaling pathway, and inhibits the proliferation and migration of ...
T2032 WHI-P180 Janex 3 EGFR , VEGFR , c-RET , CDK
WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.
T63112 VEGFR-IN-3
VEGFR-IN-3 (compound 3f), a VEGFR inhibitor, exhibits potent anticancer activity by inhibiting the growth of OVCAR-4 and MDA-MB-468 cancer cells with IC50 values of 0.29 and 0.35 μM, respectively. It has potential applic...
T9473 4SC-203 FLT
4SC-203 is a multikinase inhibitor with potential antineoplastic activity. 4SC-203 selectively inhibits FMS-related tyrosine kinase 3 (FLT3/STK1), FLT3 mutated forms, and vascular endothelial growth factor receptors (VEG...
T4425 JK-P3 VEGFR
JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube format...
T22432 SU5208 3-[(Thien-2-yl)methylene]-2-indolinone VEGFR
SU5208 (3-[(Thien-2-yl)methylene]-2-indolinone) is a compound with bioactivity.SU5208 inhibits vascular endothelial growth factor receptor-2 (VEGFR2).
T79588 HCA/VEGFR-2-IN-3 VEGFR
hCA/VEGFR-2-IN-3 (compound 8j) is an indolinonylbenzenesulfonamide with potential as a dual inhibitor of cancer-associated hCA IX/XII and VEGFR-2. This compound inhibits VEGFR-2 with an IC50 of 358 nM and exhibits high a...
T22431 SU5204 3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one EGFR , VEGFR , HER
SU5204 (3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one), an analogue of SU5025, pharmacologically inhibits VEGFR2(IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) and HER2)
T79858 TIE-2/VEGFR-2 kinase-IN-3
TIE-2/VEGFR-2 kinase-IN-3, a benzimidazole derivative, serves as a potent inhibitor of the tyrosine kinase receptors TIE-2 and VEGFR-2, exhibiting IC50 values of 6.9 nM and 3.5 nM, respectively. This compound is useful f...
T2638 Gandotinib LY2784544 VEGFR , FGFR , FLT , JAK
LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM). The selectivity is higher 8- and 20-fold than JAK1 and JAK3.
T2054 Altiratinib DCC-2701 VEGFR , Tie-2 , FLT , Trk receptor , c-Met/HGFR
Altiratinib (DCC-2701)(DCC-2701) is a novel c-MET/TIE-2/VEGFR inhibitor; effectively reduce tumor burden in vivo and block c-MET pTyr(1349)-mediated signaling, cell growth and migration as compared with an HGF antagonist...
T1836 AZD2932 VEGFR , FLT , PDGFR , c-Kit
AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.
T0093L Sorafenib Bay 43-9006 Apoptosis , Raf , VEGFR , FLT , Ferroptosis , PDGFR , c-Kit , Autophagy
Sorafenib (Bay 43-9006) is a multikinase inhibitor that inhibits Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57/58 nM) with oral activity. Sorafenib has antitumor activity...
T8482 Ripretinib DCC-2618 Apoptosis , VEGFR , FLT , PDGFR , c-Kit
Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.
T2358 ENMD-2076 Apoptosis , VEGFR , FGFR , FLT , c-RET , PDGFR , Src , Aurora Kinase
ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.
T0093 Sorafenib tosylate Bay 43-9006 Apoptosis , Raf , VEGFR , FLT , Ferroptosis , PDGFR , c-Kit , Autophagy
Sorafenib tosylate (Bay 43-9006) is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).
T4053 AST 487 NVP-AST 487 VEGFR , FLT , c-RET , Bcr-Abl , c-Kit
AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.
T7493 AG-13958 AG-013958 VEGFR
AG-13958 (AG-013958) (AG-013958), a potent VEGFR tyrosine kinase inhibitor, for the treatment of age-related macular degeneration.
T2586 Cabozantinib XL184,BMS-907351 Apoptosis , VEGFR , FLT , c-Met/HGFR , c-RET , TAM Receptor , c-Kit
Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM). Cabozantinib exhibits both antitumor and antiangiogenic activity...
T4349 Sitravatinib MG516,MGCD516 Discoidin Domain Receptor (DDR) , VEGFR , FLT , Trk receptor , TAM Receptor , c-Kit , Ephrin Receptor
Sitravatinib (MGCD516) (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRα/β, PDGFR, and Axl.
T6479 Dovitinib lactate hydrate Dovitinib (TKI258) Lactate,Dovitinib Lactate,TKI258 VEGFR , FGFR , FLT , PDGFR , c-Kit
Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) R...
T2514 Linifanib ABT-869,RG3635,AL-39324 Apoptosis , c-Fms , VEGFR , FLT , CSF-1R , PDGFR , c-Kit , Autophagy
Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and PDGFRβ (IC50: 66 nM). Linifanib may exhibit potent antiprolife...
T6289 Dovitinib TKI258,CHIR-258 VEGFR , FGFR , FLT , PDGFR , c-Kit
Dovitinib (CHIR-258) (TKI258, CHIR258) is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit, IC50: 1/2 nM), also effective to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs (IC50: 8-13 nM), less potent to E...
T7104 Dovitinib lactate CHIR-258 lactate,TKI-258 lactate VEGFR , FGFR , FLT , PDGFR , c-Kit
Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).
T5164 Cabozantinib hydrochloride XL184,Cabozantinib hydrochloride (849217-68-1(free base)),BMS-907351 VEGFR , FLT , c-Met/HGFR , TAM Receptor , c-Kit , ROR
Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6 nM).
T6028 PF 477736 PF 00477736,PF-477736,PF-736,PF-00477736,PF477736 c-Fms , VEGFR , FGFR , FLT , c-RET , Chk , CDK , Src , Aurora Kinase
PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (CSF1R), Ret and Yes.
T63505 Tivozanib hydrochloride hydrate AV-951 hydrochloride hydrate,KRN951 hydrochloride hydrate VEGFR
Tivozanib hydrochloride hydrate (AV-951 hydrochloride hydrate) is an orally active, selective, and potent vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitor that inhibits VEGFR-1, VEGFR-2, and ...
T3691 (Rac)-SAR131675 SAR131675 VEGFR
(Rac)-SAR131675 is an effective and specific VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity (IC50: 20 nmol/L) and VEGFR-3 autophosphorylation (IC50: 45 nmol/L) in HEK cells, respectively. SAR131675 is h...
T11153 EG00229 Others
EG00229 is a neuropilin 1 (NRP1) receptor antagonist that selectively inhibits the binding of VEGF-A to the NRP1 b1 domain, achieving this inhibition with an IC50 value of 3 μM. It does not affect the binding of VEGF-A t...
T8496 MAZ51 Apoptosis , VEGFR
MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.
T3463 NVP-ACC789 ACC-789,ZK202650 VEGFR , PDGFR
ACC-789 (NVP-ACC789 (ZK202650); ZK-202650) is an effective, specific and orally active inhibitor of the VEGF receptor tyrosine kinases.
T6036 Brivanib BMS-540215 EGFR , VEGFR , FGFR , Autophagy
Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold against PDGFR-β. Phase 3.
T16909 Donafenib Sorafenib (D3),Bay 43-9006 (D3),Sorafenib-d3 Raf , VEGFR
Donafenib (Bay 43-9006 (D3)) is a deuterium-labeled Sorafenib which is a multikinase inhibitor(IC50s: 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively).
T0263 Chloropyramine hydrochloride Nilfan,Alergosan,Halopyramine hydrochloride FAK , VEGFR , Histamine Receptor
Chloropyramine hydrochloride (Alergosan) is a histamine receptor H1 antagonist.
T0097L Pazopanib GW786034 VEGFR , FGFR , PDGFR , c-Kit , Autophagy
Pazopanib (GW786034), a small molecule inhibitor, inhibits multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibits VEGFR-1, -2 and -3, c-kit and PDGF-R, which may result i...
T2500 Cediranib AZD2171,NSC-732208 VEGFR , FLT , PDGFR , c-Kit , Autophagy
Cediranib (AZD2171) (AZD2171) is a highly potent (IC50 < 1 nmol/L) ATP-competitive inhibitor of recombinant KDR tyrosine kinase in vitro, also inhibits Flt1/4 (IC50: 5 nM/≤3 nM), similar activity against PDGFRβ and c-Kit...
T2288 Motesanib AMG 706 VEGFR , c-Kit
Motesanib (AMG 706) is an orally bioavailable receptor tyrosine kinase inhibitor with potential antineoplastic activity. AMG 706 selectively targets and inhibits vascular endothelial growth factor (VEGFR), platelet-deriv...
T14943 CGP60474 VEGFR , CDK , PKC
CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC. CGP60474 is also a highly potent anti-endotoxemic agent and inhibits cyclin-dependent kinase (CDK) potently.
T2456 Tivozanib AV-951,KRN951 VEGFR , PDGFR , Ephrin Receptor
Tivozanib (KRN951) is an orally bioavailable inhibitor of vascular endothelial growth factor receptors (VEGFRs) 1, 2 and 3 with potential antiangiogenic and antineoplastic activities.
T2624 OSI-930 OSI 930 Apoptosis , c-Fms , Raf , VEGFR , FLT , CSF-1R , Src , c-Kit
OSI-930, an orally active inhibitor of c-Kit and the vascular endothelial growth factor receptor-2 (VEGFR-2), targets cancer cell proliferation and blood vessel growth (angiogenesis) in tumors.
T2656 Fruquintinib HMPL-013 VEGFR
Fruquintinib (HMPL-013) is an orally available, small molecule inhibitor of vascular endothelial growth factor receptors (VEGFRs), with potential anti-angiogenic and antineoplastic activities.
T1656L Vandetanib Fumarate HSDB 8198,Zactima,Caprelsa,ZD 6474,Vandetanib
Vandetanib Fumarate is an orally available tyrosine kinase inhibitor. Vandetanib Fumarate works by blocking RET (REarranged during Transfection), vascular endothelial growth factor receptor (VEGFR-2, VEGFR-3), and epider...
T77148 Pegdinetanib
Pegdinetanib (BMS-844203; CT-322) is a selective inhibitor targeting VEGFR-2 (VEGFR), exhibiting dissociation constants (Kd) of 11 nM and 250 nM and half-maximal inhibitory concentrations (IC50) of 16 nM and 240 nM for h...
T79495 VEGFR-2-IN-32 VEGFR
VEGFR-2-IN-32 (Comp 3a) is an inhibitor of VEGFR-2, exhibiting an inhibitory concentration (IC 50) of 8.93 nM, and demonstrates cytotoxic activity towards PC-3 cells with an IC 50 of 1.22 μM, indicating its potential uti...
T63870 Multi-kinase-IN-3
Multi-kinase-IN-3 (compound 2) is a potent inhibitor of angiokinase and inhibits VEGFR-2 (IC50: 58.3 nM) and PDGFRβ (IC50: 55 nM).
T12791 (S)-3-Hydroxy Midostaurin (S)-CGP52421 Others
(S)-3-Hydroxy Midostaurin is a potent inhibitor of kinases(IC50 of <400 nM for 13 kinases (VEGFR-2, TRK-A, FLT3, et)).
T74127 N-Desethyl Sunitinib hydrochloride
N-Desethyl Sunitinib (SU-12662) (hydrochloride), a metabolite of sunitinib, is a robust ATP-competitive inhibitor of VEGFR, PDGFRβ, and KIT, demonstrating inhibition constants (K i values) of 2, 9, 17, 8, and 4 nM for VE...
T12145 N-Desethyl Sunitinib SU-11662 VEGFR , PDGFR , c-Kit
N-Desethyl Sunitinib (SU-11662) is a sunitinib metabolite.
T74422 Sozinibercept
Sozinibercept (OPT 302; VGX-300) is a soluble form of Vascular Endothelial Growth Factor Receptor-3 (VEGFR-3) that potently inhibits the activity of Vascular Endothelial Growth Factor-C and -D (VEGF-C/D), key proangiogen...
T71576 SIM010603
SIM010603 is a structurally novel, oral, multi-targeted receptor tyrosine kinase inhibitor. SIM010603 inhibited stem cell factor receptor (Kit), vascular endothelial growth factor receptor-2 (VEGFR-2), platelet-derived g...

Compounds

VEGFR-3-IN-1
T72924
Synonym:
Target: VEGFR
WHI-P180
T2032
Synonym: Janex 3
Target: EGFR, VEGFR, c-RET, CDK
VEGFR-IN-3
T63112
Synonym:
Target:
4SC-203
T9473
Synonym:
Target: FLT
JK-P3
T4425
Synonym:
Target: VEGFR
SU5208
T22432
Synonym: 3-[(Thien-2-yl)methylene]-2-indolinone
Target: VEGFR
hCA/VEGFR-2-IN-3
T79588
Synonym:
Target: VEGFR
SU5204
T22431
Synonym: 3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one
Target: EGFR, VEGFR, HER
TIE-2/VEGFR-2 kinase-IN-3
T79858
Synonym:
Target:
Gandotinib
T2638
Synonym: LY2784544
Target: VEGFR, FGFR, FLT, JAK
Altiratinib
T2054
Synonym: DCC-2701
Target: VEGFR, Tie-2, FLT, Trk receptor, c-Met/HGFR
AZD2932
T1836
Synonym:
Target: VEGFR, FLT, PDGFR, c-Kit
Sorafenib
T0093L
Synonym: Bay 43-9006
Target: Apoptosis, Raf, VEGFR, FLT, Ferroptosis, PDGFR, c-Kit, Autophagy
Ripretinib
T8482
Synonym: DCC-2618
Target: Apoptosis, VEGFR, FLT, PDGFR, c-Kit
ENMD-2076
T2358
Synonym:
Target: Apoptosis, VEGFR, FGFR, FLT, c-RET, PDGFR, Src, Aurora Kinase
Sorafenib tosylate
T0093
Synonym: Bay 43-9006
Target: Apoptosis, Raf, VEGFR, FLT, Ferroptosis, PDGFR, c-Kit, Autophagy
AST 487
T4053
Synonym: NVP-AST 487
Target: VEGFR, FLT, c-RET, Bcr-Abl, c-Kit
AG-13958
T7493
Synonym: AG-013958
Target: VEGFR
Cabozantinib
T2586
Synonym: XL184,BMS-907351
Target: Apoptosis, VEGFR, FLT, c-Met/HGFR, c-RET, TAM Receptor, c-Kit
Sitravatinib
T4349
Synonym: MG516,MGCD516
Target: Discoidin Domain Receptor (DDR), VEGFR, FLT, Trk receptor, TAM Receptor, c-Kit, Ephrin Receptor
Dovitinib lactate hydrate
T6479
Synonym: Dovitinib (TKI258) Lactate,Dovitinib Lactate,TKI258
Target: VEGFR, FGFR, FLT, PDGFR, c-Kit
Linifanib
T2514
Synonym: ABT-869,RG3635,AL-39324
Target: Apoptosis, c-Fms, VEGFR, FLT, CSF-1R, PDGFR, c-Kit, Autophagy
Dovitinib
T6289
Synonym: TKI258,CHIR-258
Target: VEGFR, FGFR, FLT, PDGFR, c-Kit
Dovitinib lactate
T7104
Synonym: CHIR-258 lactate,TKI-258 lactate
Target: VEGFR, FGFR, FLT, PDGFR, c-Kit
Cabozantinib hydrochloride
T5164
Synonym: XL184,Cabozantinib hydrochloride (849217-68-1(free base)),BMS-907351
Target: VEGFR, FLT, c-Met/HGFR, TAM Receptor, c-Kit, ROR
PF 477736
T6028
Synonym: PF 00477736,PF-477736,PF-736,PF-00477736,PF477736
Target: c-Fms, VEGFR, FGFR, FLT, c-RET, Chk, CDK, Src, Aurora Kinase
Tivozanib hydrochloride hydrate
T63505
Synonym: AV-951 hydrochloride hydrate,KRN951 hydrochloride hydrate
Target: VEGFR
(Rac)-SAR131675
T3691
Synonym: SAR131675
Target: VEGFR
EG00229
T11153
Synonym:
Target: Others
MAZ51
T8496
Synonym:
Target: Apoptosis, VEGFR
NVP-ACC789
T3463
Synonym: ACC-789,ZK202650
Target: VEGFR, PDGFR
Brivanib
T6036
Synonym: BMS-540215
Target: EGFR, VEGFR, FGFR, Autophagy
Donafenib
T16909
Synonym: Sorafenib (D3),Bay 43-9006 (D3),Sorafenib-d3
Target: Raf, VEGFR
Chloropyramine hydrochloride
T0263
Synonym: Nilfan,Alergosan,Halopyramine hydrochloride
Target: FAK, VEGFR, Histamine Receptor
Pazopanib
T0097L
Synonym: GW786034
Target: VEGFR, FGFR, PDGFR, c-Kit, Autophagy
Cediranib
T2500
Synonym: AZD2171,NSC-732208
Target: VEGFR, FLT, PDGFR, c-Kit, Autophagy
Motesanib
T2288
Synonym: AMG 706
Target: VEGFR, c-Kit
CGP60474
T14943
Synonym:
Target: VEGFR, CDK, PKC
Tivozanib
T2456
Synonym: AV-951,KRN951
Target: VEGFR, PDGFR, Ephrin Receptor
OSI-930
T2624
Synonym: OSI 930
Target: Apoptosis, c-Fms, Raf, VEGFR, FLT, CSF-1R, Src, c-Kit
Fruquintinib
T2656
Synonym: HMPL-013
Target: VEGFR
Vandetanib Fumarate
T1656L
Synonym: HSDB 8198,Zactima,Caprelsa,ZD 6474,Vandetanib
Target:
Pegdinetanib
T77148
Synonym:
Target:
VEGFR-2-IN-32
T79495
Synonym:
Target: VEGFR
Multi-kinase-IN-3
T63870
Synonym:
Target:
(S)-3-Hydroxy Midostaurin
T12791
Synonym: (S)-CGP52421
Target: Others
N-Desethyl Sunitinib hydrochloride
T74127
Synonym:
Target:
N-Desethyl Sunitinib
T12145
Synonym: SU-11662
Target: VEGFR, PDGFR, c-Kit
Sozinibercept
T74422
Synonym:
Target:
SIM010603
T71576
Synonym:
Target:
1 2
カタログ番号 製品名 別名 ターゲット
TN2019 Orobol 3'-Hydroxygenistein,3’,4’,5,7-tetrahydroxy-isoflavon BCL , Caspase , PI3K
Orobol (3’,4’,5,7-tetrahydroxy-isoflavon) is an inhibitor of tyrosine-specific protein kinase and phosphatidylinositol turnover. Orobol inhibits PI3K isoforms with IC50s of 3.46-5.27 μM for PI3K α/β/γ/K/δ. Orobol exhibit...
T13108 Pamufetinib H2OL3Q4XRD,4-(2-Fluoro-4-(3-(2-phenylacetyl)thioureido)phenoxy)-7-methoxy-N-methylquinoline-6-carboxamide,TAS-115 VEGFR , c-Met/HGFR
Pamufetinib (TAS-115) is a potent inhibitor of VEGFR and hepatocyte growth factor receptor (c-Met/HGFR)-targeted kinase(IC50s of 30 and 32 nM for rVEGFR2 and rMET, respectively).
T1152 Albendazole SKF-62979 HIF/HIF Prolyl-Hydroxylase , Microtubule Associated , Antibiotic , Parasite
Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-01936 VEGFR3/FLT4 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
VEGFR3/FLT4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.4 kDa and the accession number is P35917-1.
TMPY-00949 VEGFR3/FLT4 Protein, Human, Recombinant (His) Human HEK293 Cells
VEGFR3/FLT4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86 kDa and the accession number is P35916-1.
TMPK-00446 VEGFR3/FLT4 Protein, Human, Recombinant (aa 25-776, His & Avi), Biotinylated Human HEK293 Cells
Vascular endothelial growth factor (VEGF) and its receptors VEGF-R1, -R2 and -R3 play important roles in tumor angiogenesis and are associated with poor prognosis in several solid tumors.VEGF-R1, -R2 and -R3 were highly ...
TMPK-00445 VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
Vascular endothelial growth factor (VEGF) and its receptors VEGF-R1, -R2 and -R3 play important roles in tumor angiogenesis and are associated with poor prognosis in several solid tumors.VEGF-R1, -R2 and -R3 were highly ...
TMPY-01937 VEGFR3/FLT4 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
VEGFR3/FLT4 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 112 kDa and the accession number is P35917-1.
TMPY-06620 VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 87.80 kDa and the accession number is NP_002011.2.
TMPY-01069 VEGFR3/FLT4 Protein, Human, Recombinant (hFc) Human HEK293 Cells
VEGFR3/FLT4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 111.3 kDa and the accession number is P35916-1.
TMPY-00892 Neuropilin-2 Protein, Human, Recombinant (His) Human HEK293 Cells
Neuropilin-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 95 kDa and the accession number is O60462-3.
TMPY-01897 PRSS3 Protein, Human, Recombinant (His) Human HEK293 Cells
Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains on...
TMPY-05191 CD47 Protein, Human, Recombinant, Biotinylated Human HEK293 Cells
CD47 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.
TMPY-03763 Neuropilin-2 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Neuropilin-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 120.7 kDa and the accession number is O60462-3.
TMPY-01020 Periostin/OSF-2 Protein, Human, Recombinant (His) Human HEK293 Cells
Periostin/OSF-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.4 kDa and the accession number is Q15063-3.
TMPY-04683 CD47 Protein, Human, Recombinant Human HEK293 Cells
CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.
TMPY-00357 HNT/NTM Protein, Human, Recombinant (His) Human HEK293 Cells
HNT/NTM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.3 kDa and the accession number is Q9P121-3.
TMPY-06986 FGF-8b Protein, Human, Recombinant Human E. coli
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment...
TMPY-04142 RANK/TNFRSF11A Protein, Human, Recombinant (hFc) Human HEK293 Cells
RANK/TNFRSF11A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.8 kDa and the accession number is Q9Y6Q6-3.
TMPY-00132 Mesothelin Protein, Human, Recombinant Human HEK293 Cells
Mesothelin Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 32.4 kDa and the accession number is Q13421-3.
TMPY-05748 CD45 Protein, Human, Recombinant (aa 26-577, His) Human HEK293 Cells
CD45 Protein, Human, Recombinant (aa 26-577, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.2 kDa and the accession number is P08575-3.
TMPY-04298 CDCP1 Protein, Human, Recombinant (His) Human HEK293 Cells
CDCP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.4 kDa and the accession number is Q9H5V8-3.
TMPY-04935 CD47 Protein, Human, Recombinant (aa 1-139, His) Human HEK293 Cells
CD47 Protein, Human, Recombinant (aa 1-139, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is Q08722-3.
TMPY-00072 GITR/TNFRSF18 Protein, Human, Recombinant (His) Human HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16 kDa and the accession number is Q9Y5U5-3.
TMPJ-01099 IL-15RA Protein, Human, Recombinant (hFc, Human Cells) Human HEK293 Cells
Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bi...
TMPY-01180 CD86 Protein, Human, Recombinant (His) Human HEK293 Cells
CD86 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is P42081-3.
TMPY-00480 NCAM1 Protein, Human, Recombinant (His) Human HEK293 Cells
NCAM1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66.1 kDa and the accession number is P13591-3.
TMPY-05246 CD86 Protein, Human, Recombinant (His), Biotinylated Human HEK293 Cells
CD86 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P42081-3.
TMPY-03621 EphB2 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
EphB2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.6 kDa and the accession number is P54763-3.
TMPY-00276 PLGF/PGF Protein, Human, Recombinant (mFc) Human HEK293 Cells
PLGF/PGF Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 43.7 kDa and the accession number is P49763-3.
TMPJ-00391 FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc) Human HEK293 Cells
FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 85-120 KDa and the accession number is P21802-3.
TMPY-02691 IL-17RC Protein, Human, Recombinant(aa 1-454, hFc) Human HEK293 Cells
IL-17RC Protein, Human, Recombinant(aa 1-454, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 75.3 kDa and the accession number is Q8NAC3-3.
TMPY-03435 NCKIPSD Protein, Human, Recombinant (GST) Human E. coli
NCKIPSD is localized exclusively in the cell nucleus. It plays a role in signal transduction and may function in the maintenance of sarcomeres and the assembly of myofibrils into sarcomeres. NCKIPSD also plays an importa...
TMPK-00398 FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi) Human HEK293 Cells
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi) is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3.
TMPJ-00054 PLGF-2 Protein, Human, Recombinant (His) Human HEK293 Cells
Placental growth factor is a protein that in humans is encoded by the PGF gene. It is a secreted protein and belongs to the PDGF/VEGF growth factor family. Alternate splicing results in at least three human mature PlGF f...
TMPY-05514 RANK/TNFRSF11A Protein, Human, Recombinant (mFc) Human HEK293 Cells
RANK/TNFRSF11A Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 46.5 kDa and the accession number is Q9Y6Q6-3.
TMPY-03960 COL9A1 Protein, Human, Recombinant (His) Human HEK293 Cells
COL9A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.2 kDa and the accession number is P20849-3.
TMPY-04386 EphB2 Protein, Human, Recombinant (aa 570-987, His & GST) Human Baculovirus Insect Cells
EphB2 Protein, Human, Recombinant (aa 570-987, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75.2 kDa and the accession number is P29323-3.
TMPJ-01288 KLF6 Protein, Human, Recombinant Human E. coli
Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by ...
TMPK-00447 CD45 Protein, Human, Recombinant (aa 26-577, hFc) Human HEK293 Cells
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) com...
TMPY-03883 CD47 Protein, Human, Recombinant (hFc) Human HEK293 Cells
CD47 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.7 kDa and the accession number is Q08722-3.
TMPK-00399 FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated Human HEK293 Cells
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3.
TMPY-06411 GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 17.79 kDa and the accession number is Q9Y5U5-3.
TMPJ-00899 HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc) Human HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 65 KDa and the accession number is P21860-3.
TMPY-01656 VEGF183 Protein, Human, Recombinant Human Baculovirus Insect Cells
VEGF183 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 21 kDa and the accession number is P15692-3.
TMPY-05383 NKp30/NCR3 Protein, Human, Recombinant (hFc) Human HEK293 Cells
NKp30/NCR3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.6 kDa and the accession number is O14931-3.
TMPY-01268 SMYD3 Protein, Human, Recombinant (GST) Human Baculovirus Insect Cells
SET and MYND domain-containing protein 3, also known as Zinc finger MYND domain-containing protein 1, SMYD3, and ZMYND, is a member of the histone-lysine methyltransferase family. SMYD3 contains one MYND-type zinc finger...
TMPY-04273 FGFR2 Protein, Human, Recombinant (aa 1-378, His) Human HEK293 Cells
FGFR2 Protein, Human, Recombinant (aa 1-378, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 41.1 kDa and the accession number is P21802-3.
TMPY-05590 NCAM1 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
NCAM1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 67.9 kDa and the accession number is P13591-3.
TMPY-04157 RANK/TNFRSF11A Protein, Human, Recombinant (His) Human HEK293 Cells
RANK/TNFRSF11A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.5 kDa and the accession number is Q9Y6Q6-3.
TMPY-03969 SUSD4 Protein, Human, Recombinant (mFc) Human HEK293 Cells
SUSD4, also known as sushi domain-containing protein 4, is a hypothetical cell surface protein whose tissue distribution and function are completely unknown. SUSD4 is detectable in murine brains, eyes, spinal cords, and ...
TMPJ-00390 FGFR2IIIb Protein, Human, Recombinant (hFc) Human HEK293 Cells
FGFR2IIIb Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 70-90 KDa and the accession number is P21802-3.
TMPY-04216 EphB2 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
EphB2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.3 kDa and the accession number is P54763-3.
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VEGFR3/FLT4 Protein, Mouse, Recombinant (His)
TMPY-01936
Species: Mouse
Expression System: HEK293 Cells
VEGFR3/FLT4 Protein, Human, Recombinant (His)
TMPY-00949
Species: Human
Expression System: HEK293 Cells
VEGFR3/FLT4 Protein, Human, Recombinant (aa 25-776, His & Avi), Biotinylated
TMPK-00446
Species: Human
Expression System: HEK293 Cells
VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi)
TMPK-00445
Species: Human
Expression System: HEK293 Cells
VEGFR3/FLT4 Protein, Mouse, Recombinant (hFc)
TMPY-01937
Species: Mouse
Expression System: HEK293 Cells
VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06620
Species: Human
Expression System: HEK293 Cells
VEGFR3/FLT4 Protein, Human, Recombinant (hFc)
TMPY-01069
Species: Human
Expression System: HEK293 Cells
Neuropilin-2 Protein, Human, Recombinant (His)
TMPY-00892
Species: Human
Expression System: HEK293 Cells
PRSS3 Protein, Human, Recombinant (His)
TMPY-01897
Species: Human
Expression System: HEK293 Cells
CD47 Protein, Human, Recombinant, Biotinylated
TMPY-05191
Species: Human
Expression System: HEK293 Cells
Neuropilin-2 Protein, Human, Recombinant (hFc)
TMPY-03763
Species: Human
Expression System: HEK293 Cells
Periostin/OSF-2 Protein, Human, Recombinant (His)
TMPY-01020
Species: Human
Expression System: HEK293 Cells
CD47 Protein, Human, Recombinant
TMPY-04683
Species: Human
Expression System: HEK293 Cells
HNT/NTM Protein, Human, Recombinant (His)
TMPY-00357
Species: Human
Expression System: HEK293 Cells
FGF-8b Protein, Human, Recombinant
TMPY-06986
Species: Human
Expression System: E. coli
RANK/TNFRSF11A Protein, Human, Recombinant (hFc)
TMPY-04142
Species: Human
Expression System: HEK293 Cells
Mesothelin Protein, Human, Recombinant
TMPY-00132
Species: Human
Expression System: HEK293 Cells
CD45 Protein, Human, Recombinant (aa 26-577, His)
TMPY-05748
Species: Human
Expression System: HEK293 Cells
CDCP1 Protein, Human, Recombinant (His)
TMPY-04298
Species: Human
Expression System: HEK293 Cells
CD47 Protein, Human, Recombinant (aa 1-139, His)
TMPY-04935
Species: Human
Expression System: HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (His)
TMPY-00072
Species: Human
Expression System: HEK293 Cells
IL-15RA Protein, Human, Recombinant (hFc, Human Cells)
TMPJ-01099
Species: Human
Expression System: HEK293 Cells
CD86 Protein, Human, Recombinant (His)
TMPY-01180
Species: Human
Expression System: HEK293 Cells
NCAM1 Protein, Human, Recombinant (His)
TMPY-00480
Species: Human
Expression System: HEK293 Cells
CD86 Protein, Human, Recombinant (His), Biotinylated
TMPY-05246
Species: Human
Expression System: HEK293 Cells
EphB2 Protein, Mouse, Recombinant (hFc)
TMPY-03621
Species: Mouse
Expression System: HEK293 Cells
PLGF/PGF Protein, Human, Recombinant (mFc)
TMPY-00276
Species: Human
Expression System: HEK293 Cells
FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc)
TMPJ-00391
Species: Human
Expression System: HEK293 Cells
IL-17RC Protein, Human, Recombinant(aa 1-454, hFc)
TMPY-02691
Species: Human
Expression System: HEK293 Cells
NCKIPSD Protein, Human, Recombinant (GST)
TMPY-03435
Species: Human
Expression System: E. coli
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)
TMPK-00398
Species: Human
Expression System: HEK293 Cells
PLGF-2 Protein, Human, Recombinant (His)
TMPJ-00054
Species: Human
Expression System: HEK293 Cells
RANK/TNFRSF11A Protein, Human, Recombinant (mFc)
TMPY-05514
Species: Human
Expression System: HEK293 Cells
COL9A1 Protein, Human, Recombinant (His)
TMPY-03960
Species: Human
Expression System: HEK293 Cells
EphB2 Protein, Human, Recombinant (aa 570-987, His & GST)
TMPY-04386
Species: Human
Expression System: Baculovirus Insect Cells
KLF6 Protein, Human, Recombinant
TMPJ-01288
Species: Human
Expression System: E. coli
CD45 Protein, Human, Recombinant (aa 26-577, hFc)
TMPK-00447
Species: Human
Expression System: HEK293 Cells
CD47 Protein, Human, Recombinant (hFc)
TMPY-03883
Species: Human
Expression System: HEK293 Cells
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated
TMPK-00399
Species: Human
Expression System: HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06411
Species: Human
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc)
TMPJ-00899
Species: Human
Expression System: HEK293 Cells
VEGF183 Protein, Human, Recombinant
TMPY-01656
Species: Human
Expression System: Baculovirus Insect Cells
NKp30/NCR3 Protein, Human, Recombinant (hFc)
TMPY-05383
Species: Human
Expression System: HEK293 Cells
SMYD3 Protein, Human, Recombinant (GST)
TMPY-01268
Species: Human
Expression System: Baculovirus Insect Cells
FGFR2 Protein, Human, Recombinant (aa 1-378, His)
TMPY-04273
Species: Human
Expression System: HEK293 Cells
NCAM1 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-05590
Species: Human
Expression System: HEK293 Cells
RANK/TNFRSF11A Protein, Human, Recombinant (His)
TMPY-04157
Species: Human
Expression System: HEK293 Cells
SUSD4 Protein, Human, Recombinant (mFc)
TMPY-03969
Species: Human
Expression System: HEK293 Cells
FGFR2IIIb Protein, Human, Recombinant (hFc)
TMPJ-00390
Species: Human
Expression System: HEK293 Cells
EphB2 Protein, Mouse, Recombinant (His)
TMPY-04216
Species: Mouse
Expression System: HEK293 Cells
カタログ番号 製品名
L1610 FDA-Approved Kinase Inhibitor Library

263 compounds
A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.
L1600 Kinase Inhibitor Library

2720 compounds
A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;