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カタログ番号 | 製品名 | 別名 | ターゲット |
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T5203 | Sodium Tartrate | Others | |
Sodium Tartrate is a food additive, used as an emulsifier and binding agent in food products. | |||
T6554 | JZL 184 | JZL184 | Lipase |
JZL 184 is a potent and selective inhibitor of MAGL with IC50 of 8 nM and 4 μM for inhibition of MAGL and FAAH in mouse brain membranes respectively. | |||
T29126 | VU0360172 | VU-0360172,VU 0360172 | GluR |
VU0360172 is a positive allosteric modulator of mGlu5 receptors (EC50 = 16 nM; Ki = 195 nM). | |||
T1142 | Clindamycin phosphate | Clindamycin 2-phosphate,Clindamycin 2-dihydrogen phosphate,NSC 618653,U-28508 | ribosome , Antibacterial , Antibiotic , Parasite |
Clindamycin Phosphate is the phosphate salt form of clindamycin, a semi-synthetic, chlorinated broad-spectrum antibiotic produced by chemical modification of lincomycin. Clindamycin phosphate (Clindamycin 2-dihydrogen ph... | |||
T11527L | H-Ser-His-OH acetate | Endogenous Metabolite | |
H-Ser-His-OH acetate is an endogenous metabolite hydrolysis cleavage activity. | |||
T67965 | Torbafylline | cAMP , PI3K , PDE | |
Torbafylline, a xanthine derivative, is a phosphodiesterase (PDE) inhibitor that attenuates burn-induced protein hydrolysis in rat skeletal muscle through activation of the PDE4/cAMP/EPAC/PI3K/Akt pathway, and inhibits t... | |||
T22592 | ATPγS tetralithium salt | ATP-gamma-S tetralithium salt | PERK |
ATPγS tetralithium salt is a substrate for nucleotide hydrolysis and RNA unraveling activity of the eukaryotic translation initiation factor eIF4A, associated with p97 mutants and prions. | |||
T13353 | Xanomeline oxalate | LY246708 oxalate | AChR |
Xanomeline oxalate (LY246708 oxalate), a potent and selective muscarinic receptor agonist (SMRA), effectively stimulates in vivo phosphoinositide hydrolysis. It is a valuable compound for Alzheimer's disease research. | |||
T16290 | NIK SMI1 | NF-κB | |
NIK SMI1 is an effective and selective NF-κB inducing kinase (NIK) inhibitor. It also inhibits NIK-catalyzed hydrolysis of ATP to ADP (IC50: 0.23±0.17 nM). | |||
T74040 | Boc-Gln-Ala-Arg-AMC hydrochloride | ||
Boc-Gln-Ala-Arg-AMC hydrochloride is a fluorescent compound that serves as a substrate for trypsin and is also used to determine the protein hydrolysis activity of TMPRSS2. | |||
T6941 | PI-1840 | PI 1840 | PARP , Proteasome |
PI-1840(IC50 = 27 nM)is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and postglutamyl-peptide-hydrolysis-like (PGPH-L). | |||
T23411L | T-0156 | T 0156 | PDE , Parasite |
T-0156 is a novel, potent and selective phosphodiesterase type 5 inhibitor that inhibits the hydrolysis of cyclic guanosine monophosphate (cGMP) with low affinity for PDE6, PDE1, PDE2, PDE3 and PDE4. | |||
T41308L | Gly-Phe β-naphthylamide acetate | Gly-Phe β-naphthylamide acetate(21438-66-4 Free base) | Others |
Gly-Phe β-naphthylamide acetate is the substrate of Cathepsin C and can be used for research on the function of cathepsin C, intralysosomal hydrolysis and lysosomal membrane permeability. | |||
T8172 | 2-O-α-D-Glucopyranosyl-L-ascorbic Acid | ASCORBYL GLUCOSIDE | Others |
2-O-α-D-Glucopyranosyl-L-ascorbic Acid (ASCORBYL GLUCOSIDE), a glucoside derivative of ascorbic acid, demonstrates anti-cancer activity following enzymatic hydrolysis to ascorbic acid. | |||
T19709 | Nitrocefin | Others | |
Nitrocefin is an antibiotic. It being sensitive to hydrolysis by all lactamases produced by gram-positive and gram-negative bacteria. | |||
T2400 | Candesartan Cilexetil | TCV-116 | Apoptosis , RAAS |
Candesartan Cilexetil (TCV-116) is an angiotensin II receptor antagonist (IC50: 0.26 nM). After hydrolysis of candesartan cilexetil to candesartan during gastrointestinal absorption, candesartan selectively competes with... | |||
T13568L | BCX 1470 hydrochloride | BCX 1470 hydrochloride(217099-43-9 Free base),BCX1470 HCl | Serine Protease , Complement System |
BCX 1470 hydrochloride is a potent serine protease inhibitor with anti-inflammatory activity that inhibits the ester hydrolysis and haemolytic activity of factor D and C1s, and can be used to study oedema. | |||
T7449 | O-Phenanthroline monohydrate | Phenanthroline monohydrate,1, 10-Phenanthroline monohydrate | MMP |
o-Phenanthroline monohydrate (1, 10-Phenanthroline monohydrate) is an inhibitor of metallopeptidases, inhibits zinc-dependent hydrolysis of Fa-Gly-Leu-NH2 by B. subtilis neutral protease and B. thermoproteolyticus thermo... | |||
T11221 | ERAP1-IN-1 | Others | |
ERAP1-IN-1 is an endoplasmic reticulum aminopeptidase 1 (ERAP1) inhibitor. ERAP1-IN-1 allosterically activates ERAP1’s hydrolysis of fluorogenic and chromogenic amino acid substrates but competitively inhibits its activi... | |||
T2370 | AC-55541 | AOB2796 | Proteasome , Protease-activated Receptor |
AC-55541 (AOB2796) is a novel PAR2 agonist; activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 200 to 1000 nM. | |||
T1502 | Vildagliptin | NVP-LAF 237,LAF237 | Apoptosis , Ferroptosis , Proteasome , DPP-4 |
Vildagliptin (LAF237) is a cyanopyrrolidine-based, orally bioavailable inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Vildagliptin's cyano moiety undergoes hydrolysis and this inactive metabolit... | |||
T80725 | ZK53 | Others | |
ZK53 is a selective and potent activator of mitochondrial casein hydrolase protease P (HsClpP).ZK53 induces apoptosis and inhibits the hydrolysis of alpha-casein by HsClpP.ZK53 inhibits tumour growth in xenografts and na... | |||
T39766 | Nor-NOHA monoacetate | Nor NOHA monoacetate,Nω-Hydroxy-nor-L-arginine monoacetate | Arginase |
nor-NOHA monoacetate (Nω-Hydroxy-nor-L-arginine) is a highly potent and selective arginase inhibitor. nor-NOHA monoacetate inhibits rat hepatic arginase and inhibits the hydrolysis of L-arginine, which can be used to stu... | |||
T37571 | 4-Methylumbelliferyl-β-D-Glucopyranoside | MU-GLU,4-MUG,4-MU-GLU,4-MU-β-Gluc | Others |
4-Methylumbelliferyl-β-D-Glucopyranoside (4-MU-GLU) is used in the GCase activity assay based on the catalytic hydrolysis of 4-methylumbelliferyl β-D-glucopyranoside that releases the highly fluorescent 4-methylumbellife... | |||
T41362 | EM-12 | Phthalimidinoglutarimide,2-(2,6-Dioxopiperidin-3-yl)phthalimidine | Others |
2-(2,6-Dioxopiperidin-3-yl)phthalimidine (EM-12 (2-(2,6-Dioxopiperidin-3-yl)phthalimidine)) is a teratogenic Thalidomide analogue that is more active than Thalidomide and is much more stable for hydrolysis. 2-(2,6-Dioxop... | |||
T5030 | Zofenopril calcium | SQ26991,Zofenopril (calcium) | RAAS , Reactive Oxygen Species |
Zofenopril calcium (SQ26991) is an antioxidant that acts as an angiotensin-converting enzyme inhibitor. ACE Zofenopril is a pro-drug designed to undergo metabolic hydrolysis yielding the active free sulfhydryl compound z... | |||
T4052 | KML29 | Lipase | |
KML29 is highly selective and effective monoacylglycerol lipase (MAGL) inhibitor. It has effective inhibition of human/mouse/rat MAGL (IC50: 5.9/15/43 nM). It has not inhibitory for FAAH (IC50 > 50 μM). It also effective... | |||
T22954 | LY 456236 hydrochloride | MPMQ hydrochloride | EGFR , GluR |
LY 456236 hydrochloride (MPMQ hydrochloride) is an mGlu1 receptor antagonist with an ic50 value of 143 nM. LY456236 has selective, non-competitive and oral activity, and can inhibit the hydrolysis of inositol phosphate w... | |||
T75129 | Luxdegalutamide | ARV-766 | Androgen Receptor , PROTACs |
Luxdegalutamide (ARV-766) is an orally available and effective protein degrader of protein hydrolysis-targeted chimeras (PROTAC).Luxdegalutamide degrades the wild-type androgen receptor AR, as well as AR LBD mutants incl... | |||
T4382 | Proguanil hydrochloride | Paludrine hydrochloride,Chlorguanide hydrochloride,Chloroquanil | Others , Dehydrogenase , DNA/RNA Synthesis , Antifolate , Parasite |
Proguanil hydrochloride (Chloroquanil) is a biguanide compound which metabolizes in the body to form cycloguanil, an anti-malaria agent.Upon hydrolysis, Proguanil hydrochloride is converted to its active cyclic triazine ... | |||
T1484L | Perindopril erbumine | S9490-3,Perindopril tert-butylamine salt | Apoptosis , RAAS , MRP |
Perindopril erbumine (S9490-3) is the tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Upon hydrolysis, Perindopril er... | |||
T1190 | Cefmenoxime hydrochloride | Cefmenoxime hemihydrochloride,SCE-1365 hemihydrochloride | Antibacterial , Antibiotic , Antifection |
Cefmenoxime hydrochloride (Cefmenoxime hemihydrochloride) is a cephalosporin antibiotic that is administered intravenously or intramuscularly. It is active against most common gram-positive and gram-negative microorganis... | |||
T37518 | Diphenyl disulfide | Phenyl disulfide | Apoptosis , BCL , Endogenous Metabolite |
Diphenyl disulfide (Phenyl disulfide) shows anticancer activity in breast cancer cell lines.Diphenyl disulfide induces and enhances apoptosis in breast cancer cells through Bax protein hydrolysis activation and concomita... | |||
TP1902L1 | G-Protein antagonist peptide acetate | Adrenergic Receptor | |
G-Protein antagonist peptide acetate is a truncated substance P-related peptide, competes with receptor for G protein binding. G-Protein antagonist peptide acetate inhibits the activation of Gi or Go by M2 muscarinic cho... | |||
T1682 | Methacholine Chloride | Mecholyl chloride,Acetyl-β-methylcholine chloride | AChR |
Methacholine Chloride (Acetyl-β-methylcholine chloride) is a quaternary ammonium parasympathomimetic agent with the muscarinic actions of ACETYLCHOLINE. It is hydrolyzed by ACETYLCHOLINESTERASE at a considerably slower r... | |||
T15183 | Dynarrestin | Hedgehog/Smoothened | |
Dynarrestin is an inhibitor of cytoplasmic dyneins 1 and 2. Dynarrestin suppresses hedgehog (Hh)-dependent proliferation of neuronal precursors and tumor cells. It inhibits dynein 1-driven microtubule gliding in vitro pl... | |||
T1210 | Sodium etidronate | Didronel | Phosphatase |
Sodium etidronate (Didronel) is a synthetic therapeutic diphosphonate analog of endogenous pyrophosphate. As a member of the family of drugs known as bisphosphonates, Sodium etidronate differs from endogenous pyrophospha... | |||
T39954 | AU-15330 | Epigenetic Reader Domain , PROTACs | |
AU-15330 is a protein hydrolysis-targeted chimeric (PROTAC) degrader of the SWI/SNF ATPase subunits SMARCA2 and SMARCA4.AU-15330 potently inhibits tumor growth in a prostate cancer xenograft model and acts synergisticall... | |||
T27811 | LEI-106 | ||
LEI-106, a novel potent sn-1 DAGLalpha inhibitor, blocks the hydrolysis of sn-1-oleoyl-2-AG, inhibits the hydrolysis of 2-AG by the monoacylglycerol lipase ABHD6. | |||
T30934 | CID-50930756 | CID 50930756,CID50930756 | |
CID-50930756 is a novel HCV NS3 helicase catalyzed ATP hydrolysis stimulator. | |||
T34849 | Thiocystine | ||
Thiocystine can be produced in the hydrolysis of proteins. | |||
T30042 | Ampicillinoic acid | ||
Ampicillinoic acid is a hydrolysis (ring-open) product of ampicillin. | |||
T16559 | Poloxime | PLK | |
Poloxime is a hydrolysis product of poloxin and is a non-ATP-competitive Plk1 inhibitor. It also has moderate Plk1 inhibitory activity. | |||
T30803 | Cevine | Cevin,Sabadinine | |
Cevine is a crystalline alkaloid found in sabadilla seeds and formed from cevadine by hydrolysis. | |||
T24568 | OMS-824 | OMS 824 | |
OMS-824 is a phosphodiesterase-10 inhibitor that slows or stops the hydrolysis of cAMP and cGMP. | |||
T35733 | Doramectin aglycone | ||
Doramectin aglycone is an acid degradation product of doramectin , a disaccharide-containing anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes, and its acid-catalyzed hydrolysi... | |||
T79032 | Enpp-1-IN-17 | ||
Enpp-1-IN-17 (example 274) is a potent inhibitor of ENPP1, exhibiting inhibition constants (Ki values) of 100 nM-1 μM for cGAMP hydrolysis and >1 μM for ATP hydrolysis, respectively, with a selectivity ratio of >6.4 favo... | |||
T24163 | IMR687 | IMR-687,IMR 687 | |
IMR687 is a PDE9 inhibitor that slows or stops the hydrolysis of cGMP. IMR687 can be regarded as a highly promising drug against Alzheimer's for improving memory. | |||
T37999 | Lysophosphatidylethanolamines (egg) | ||
Lysophosphatidylethanolamines (egg) are the partial hydrolysis products of phosphatidylethanolamine. | |||
T69593 | Sildenafil nitrate | ||
Sildenafil nitrate is a selective inhibitor of PDE5 (type 5 cGMP phosphodiesterase) which catalyzes the hydrolysis of 3',5'-cyclic guanosine monophosphate (cGMP). |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T41044 | Naringinase | Glucosidase | |
Naringinase is a hydrolytic enzymatic complex that exhibits α-L-rhamnosidase and β-D-glucosidase activities. It is widely found in nature and is primarily utilized for the biotransformation of steroids, antibiotics, and ... | |||
T1136 | Amylase | Diastase | Others |
Amylase (Diastase) is any one of a group of enzymes which catalyses the breakdown of starch into maltose. | |||
T35951 | Alkaline Phosphatase | Others | |
Alkaline Phosphatase is an ubiquitous membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at basic pH values. | |||
TN7243 | Fallaxsaponin A | ||
Fallaxsaponin A is isolated from the alkaline hydrolysis products of total saponins in Radix Palygalae. | |||
T19231 | Cellulase | Others | |
Cellulase is an enzyme that catalyzes the hydrolysis of certain linkages in cellulose. | |||
T4S0590 | Columbin | Phospholipase , COX , Parasite | |
1. Columbin has anti-inflammatory activity. 2. Columbin has chemopreventive ability against human colon cancer. 3. Columbin inhibits PLA2 hydrolysis of ghost RBC in a dose-dependent fashion. | |||
T19615 | α-Amylase | Amylase | |
α-Amylase, a hydrolase enzyme, catalyzes the hydrolysis of internal α-1,4-glycosidic linkages in starch, producing glucose and maltose. | |||
TN3820 | Demethoxydeacetoxypseudolaric acid B | Others | |
Demethoxydeacetoxypseudolaric acid B's the metabolic reaction of TDA in vivo is mainly occurred in blood and contributes to be the hydrolysis of plasma esterase to ester bond, as well as the glucosylation reaction. | |||
T5733 | Xylotetraose | Others | |
Xylotetraose is a hydrolysis product of Xylan. Xylan is a polysaccharide made from units of xylose and contains predominantly β-D-xylose units linked as in cellulose. | |||
T4943 | Monoolein | 1-Oleoyl-rac-glycerol | Others , Endogenous Metabolite |
Monoolein (1-Oleoyl-rac-glycerol) is a surfactant that releases free glycerol and oleic acid upon hydrolysis. Monoolein has been used in liquid crystal studies and research shows that in the presence of monoolein, the pe... | |||
TN3748 | D-Asparagine | H-D-Asn-OH | Others , Endogenous Metabolite |
D-Asparagine (H-D-Asn-OH) is a source of nitrogen for yeast strains. D-Asparagine is a competitive inhibitor of L-Asparagine hydrolysis (Ki = 0.24 mM). | |||
T4764 | 5-Methoxy-5-oxopentanoic acid | mono-Methyl glutarate,METHYL HYDROGEN GLUTARATE | Others , Endogenous Metabolite |
5-Methoxy-5-oxopentanoic acid (mono-Methyl glutarate) is a metabolite of dibasic esters(DBEs) by nasal respiratory and olfactory mucosae in vitro demonstrated that hydrolysis of DBEs yields mainly the monomethyl esters (... | |||
T21665 | DL-α-Hydroxyglutaric acid disodium salt | disodium 2-hydroxypentanedioate | Others |
DL-α-Hydroxyglutaric acid disodium salt (disodium 2-hydroxypentanedioate) is an α -hydroxyacid formed from the hydrolysis of (R) -5-oxy-2-tetrahydrofuran carboxylic acid, which is overproduced in human neurometabolic dis... | |||
TN4583 | Moringin | gp120/CD4 , IL Receptor , BCL , GSK-3 , TNF , Wnt/beta-catenin , Caspase , COX , Nrf2 , PPAR , p53 | |
Moringin is an isothiocyanate obtained from myrosinase-mediated hydrolysis of the glucosinolate precursor glucoMoringin present in Moringa oleifera seeds. Moringin has anti-inflammatory and antioxidative properties. | |||
TN6798 | Progoitrin | Others | |
Progoitrin is a biochemical from the glucosinolate family that is found in some food, which is inactive but after ingestion is converted to goitrin. Goitrin decreases the thyroid hormone production. Apart from goitrin, p... | |||
T5309 | Dimethylamine hydrochloride | N,N-Dimethylamine | Others |
Dimethylamine hydrochloride (N,N-Dimethylamine) is abundantly present in human urine. Main sources of urinary dimethylamine have been reported to include trimethylamine N-oxide, a common food component, and asymmetric d... | |||
T3332 | Isosteviol | (-)-Isosteviol | IL Receptor , Potassium Channel , TNF , NF-κB , Reactive Oxygen Species , COX , Topoisomerase |
Isosteviol ((-)-Isosteviol), a common natural sweetener, belongs to tetracyclic diterpene glycosides. The pharmacology researches have suggested that stevioside and its hydrolysis products, steviol, isosteviol and stevio... | |||
T0894 | Thiamine hydrochloride | Vitamin B1,Vitamin B1 hydrochloride,Thiamine HCl,Thiamine chloride hydrochloride | Apoptosis , HBV , Endogenous Metabolite |
Thiamine hydrochloride (Vitamin B1) is the hydrochloride salt form of thiamine, a vitamin essential for aerobic metabolism, cell growth, transmission of nerve impulses and acetylcholine synthesis. Upon hydrolysis, Thiami... | |||
T5575 | Cycloastragenol | Cyclogalegenol,Astramembrangenin | Epigenetic Reader Domain , Telomerase |
Astramembrangenin (Cycloastragenol (Astramembrangenin)) is a triterpenoid saponin compound and a hydrolysis product of the main active ingredient in Astragalus membranaceus. Cycloastragenol (CAG) may have a novel therape... | |||
T67685 | 4-Methylumbelliferyl-β-D-xylopyranoside | 4-Methylumbelliferyl-β-D-xyloside | |
4-Methylumbelliferyl-β-D-xylopyranoside (4-Methylumbelliferyl-β-D-xyloside) exhibits bursting steady-state kinetics in biological experiments, which supports the conclusion of rapid hydrolysis of the glycosidic bond of t... | |||
T7989 | Trimethyl phosphate | Others | |
Trimethyl phosphate is an organophosphorus compound that is an inhibitor of enzymes that catalyze the hydrolysis of phosphorylated compounds. It has been used as a reactant in the synthesis of peptides and other proteins... | |||
TWO2759 | Thymine | 5-methyluracil | Others , Endogenous Metabolite |
One of the pyrimidine bases of living matter. Derivation: Hydrolysis of deoxyribonucleic acid, from methylcyanoacetylurea by catalytic reduction. Use: Biochemical research. Thymine (5-methyluracil) is a pyrimidine nucleo... | |||
T4969 | Guanosine 5'-triphosphate trisodium salt | GTP Trisodium salt,5'-GTP trisodium salt | Endogenous Metabolite |
Guanosine 5'-triphosphate trisodium salt (5'-GTP trisodium salt) activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of se... | |||
T4737 | 2'-Deoxyadenosine-5'-monophosphate | D-AMP,2'-Deoxyadenosine 5'-monophosphate | Others , Endogenous Metabolite |
2'-Deoxyadenosine-5'-monophosphate (D-AMP) is a nucleoside comprised of adenine attached to a ribose (ribofuranose) moiety via a -N9-glycosidic bond. Deoxyadenosine monophosphate is a derivative of the common nucleic aci... | |||
T5089 | 5-Aminovaleric acid | Others , Endogenous Metabolite | |
5-aminovalerate (or 5-aminopentanoic acid) is a lysine degradation product. It can be produced both endogenously or through bacterial catabolism of lysine. 5-aminovalerate is formed via the following multi-step reaction:... | |||
T4826 | L-Histidine monohydrochloride monohydrat | Others , Endogenous Metabolite | |
Histidine (abbreviated as His or H) is an alpha-amino acid. The L-isomer is one of the 22 proteinogenic amino acids, i.e., the building blocks of proteins. It is classified as a charged, polar because of the hydrophilic ... | |||
T37753 | Aureusimine B | Cysteine Protease , Antibacterial | |
Aureusimine B, also known as phevalin, is a natural pyrazinone produced by certain fungi and by Staphylococcus spp., including S. aureus. Its synthesis appears to be initiated by a conserved nonribosomal peptide syntheta... | |||
T19359 | Hydrolyzed Fumonisin B2 | Others | |
Hydrolyzed Fumonisin B2 (HFB2) is a hydrolysis product of fumonisins (HF), which retains biological activity. It exhibits phytotoxicity. | |||
T13729 | Hydrolyzed Fumonisin B1 | Aminopentol | Others |
Hydrolyzed Fumonisin B1 is the backbone and the main hydrolysis product of the mycotoxin fumonisin B1 (FB1), can weakly inhibit ceramide synthase. | |||
T1607 | Hydrastinine hydrochloride | Others | |
Hydrastinine hydrochloride is a semisynthetic alkaloid from the hydrolysis of the alkaloid Hydrastine, used as a haemostatic drug. | |||
T35743 | Ivermectin B1a aglycone | ||
Ivermectin B1a aglycone is an acid degradation product produced by hydrolysis of the disaccharide unit of ivermectin. It can inhibit nematode larval development, but does not cause paralytic activity. | |||
T82625 | D-(+)-Cellotetraose | Cellotetraose | |
D-(+)-Cellotetraose, also known as Cellotetraose, is a primary hydrolysis product of cellulose [1]. | |||
TN4436 | Licoricesaponin E2 | Others | |
Licoricesaponin E2 displayed the inhibition on the growth of cancer cells with IC50 at 18.3-41.6 umol/L, it could significantly increase the cytotoxic activity after hydrolysis. | |||
T40436 | N,N'-Diacetylchitobiose | ||
N,N'-Diacetylchitobiose, a dimer of β(1,4) linked N-acetyl-D glucosamine, is derived from the hydrolysis of chitin. This compound serves as an alternative carbon source for E. coli. | |||
TN5205 | Uralsaponin D | Others | |
Uralsaponin D displayed the inhibition on the growth of cancer cells with IC50 at 18.3-41.6 μmol/L, it could significantly increase the cytotoxic activity after hydrolysis. | |||
TN1540 | Cyanidin-3,5-O-diglucoside chloride | Others | |
Cyanidin-3,5-O-diglucoside chloride has antioxidant activity. Cyanidin-3,5-O-diglucoside inhibits hyperbaric pressure-induced GLAST decrease and can be used in glaucoma studies. Cyanidin-3,5-O-diglucoside chloride is eas... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-02483 | ATP citrate lyase/ACLY Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
ATP citrate lyase, also known as Acly or Acl, is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is composed of two polymer chains which are polypeptides in human. ATP... | |||
TMPY-04125 | PTP1B Protein, Human, Recombinant (His) | Human | E. coli |
PTP1B, also known as PTPN1, belongs to the protein-tyrosine phosphatase (PTP) family. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly c... | |||
TMPY-00828 | Iduronate 2 sulfatase/IDS Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Iduronate 2-Sulfatase, also known as IDS, is a member of the highly conserved sulfatase family of enzymes that catalyze the hydrolysis of O- and N-sulfate esters from a variety of substrates. The human Iduronate 2-Sulfat... | |||
TMPH-01511 | GLO2 Protein, Human, Recombinant (GST) | Human | E. coli |
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid. | |||
TMPH-00066 | Phospholipase A2 Protein, Apis mellifera, Recombinant (His) | Apis mellifera | E. coli |
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. | |||
TMPH-03461 | IFM1 Protein, S. cerevisiae, Recombinant (GST) | Saccharomyces cerevisiae | E. coli |
One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis o... | |||
TMPH-00163 | Levanase Protein, Bacillus sp., Recombinant (His & SUMO) | Bacillus | E. coli |
Catalyzes the hydrolysis of levan with endo-type specificity. The products of levan hydrolysis are a mixture of fructose and a series of fructooligosaccharides up to 12-mer, with levantriose being the major oligosacchari... | |||
TMPH-00125 | 3-phytase A Protein, Aspergillus niger, Recombinant (His) | Aspergillus niger | P. pastoris (Yeast) |
Catalyzes the hydrolysis of inorganic orthophosphate from phytate. 3-phytase A Protein, Aspergillus niger, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 50.8 kDa and the acce... | |||
TMPJ-01393 | PGCP Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Carboxypeptidase Q (Cpq) is a member of the peptidase M28 family. PGCP is involved in a number of fundamental biological processes such as the hydrolysis of circulating peptides, catalyzing the hydrolysis of dipeptides w... | |||
TMPH-00582 | Endopeptidase Clp Protein, E. coli, Recombinant (His & Myc) | E. coli | E. coli |
Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. | |||
TMPH-00124 | 3-phytase A Protein, Aspergillus niger, Recombinant (E. coli, His) | Aspergillus niger | E. coli |
Catalyzes the hydrolysis of inorganic orthophosphate from phytate. 3-phytase A Protein, Aspergillus niger, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular we... | |||
TMPH-02378 | LpxC Protein, Klebsiella pneumoniae, Recombinant (His & Myc) | Klebsiella pneumoniae | E. coli |
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. | |||
TMPH-00555 | LpxC Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. | |||
TMPH-00209 | CLPP2 Protein, Borrelia burgdorferi, Recombinant (His & Myc) | Borrelia burgdorferi | E. coli |
Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. | |||
TMPH-02482 | HIU hydrolase Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU). HIU hydrolase Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis a... | |||
TMPH-00172 | Subtilisin E Protein, Bacillus subtilis, Recombinant (His & SUMO) | Bacillus subtilis | E. coli |
Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides. Subtilisin E Protein, Bacillus subtilis, Recombinant (His & SUMO) is expressed in E. coli expression sy... | |||
TMPH-00027 | Aculeacin-A acylase Protein, Actinoplanes utahensis, Recombinant (His & SUMO) | Actinoplanes utahensis | E. coli |
Catalyzes the hydrolysis of the palmitoyl moiety of the antifungal antibiotic, aculeacin-A, giving a hexapeptide moiety and a long chain fatty acid. Aculeacin-A acylase Protein, Actinoplanes utahensis, Recombinant (His &... | |||
TMPH-02373 | Metallo-beta-lactamase type 2 Protein, Klebsiella pneumoniae, Recombinant (His) | Klebsiella pneumoniae | E. coli |
Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring. Does not confer resistance to the polymixin colistin or the fluoroquinol... | |||
TMPH-03234 | Acetylcholinesterase Protein, Rat, Recombinant (His) | Rat | E. coli |
Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Acetylcholinesterase Protein, Rat, Recombinant (His) is expressed in E. coli express... | |||
TMPJ-01045 | Lysozyme C Protein, Human, Recombinant (His) | Human | HEK293 Cells |
lysozyme C is a secreted protein and belongs to the glycosyl hydrolase 22 family. Lysozymes have primarily a bacteriolytic function, damage bacterial cell walls by catalyzing hydrolysis of 1,4-beta-linkages between N-ace... | |||
TMPH-03190 | CPG2 Protein, Pseudomonas sp., Recombinant (GST) | Pseudomonas | E. coli |
Catalyzes the hydrolysis of reduced and non-reduced folates to pteroates and L-glutamate. This enzyme has a broad specificity. CPG2 Protein, Pseudomonas sp., Recombinant (GST) is expressed in E. coli expression system wi... | |||
TMPY-03849 | NUDT5 Protein, Human, Recombinant (His) | Human | E. coli |
NUDT5 (Nudix Hydrolase 5) is a Protein Coding gene. This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphos... | |||
TMPK-00854 | ENPP1 Protein, Human, Recombinant (C-His) | Human | HEK293 Cells |
Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (eP... | |||
TMPH-00863 | 5-oxoprolinase/OPLAH Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Catalyzes the cleavage of 5-oxo-L-proline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. 5-oxoprolinase/OPLAH Protein, Human, Recombinant (His & Myc) is expressed in E. coli expressi... | |||
TMPH-00024 | LpxC Protein, Acinetobacter baumannii, Recombinant (His) | Acinetobacter baumannii | E. coli |
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. LpxC Protein, Acinetobacter baumannii, Recombinant (His) is ... | |||
TMPH-03180 | LpxC Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) | Pseudomonas aeruginosa | E. coli |
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. LpxC Protein, Pseudomonas aeruginosa, Recombinant (His & SUM... | |||
TMPH-00840 | MAT2A Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subse... | |||
TMPK-00781 | ENPP1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (eP... | |||
TMPH-03179 | LpxC Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO) | Pseudomonas aeruginosa | E. coli |
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. LpxC Protein, Pseudomonas aeruginosa, Recombinant (His & Myc... | |||
TMPH-03488 | Metallo-beta-lactamase type 2 Protein, Serratia marcescens, Recombinant (His & Myc) | Serratia marcescens | E. coli |
Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring. Metallo-beta-lactamase type 2 Protein, Serratia marcescens, Recombinant ... | |||
TMPH-02691 | PLA2G12A Protein, Mouse, Recombinant (His & Myc) | Mouse | Baculovirus Insect Cells |
PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Does not exhibit detectable activity toward sn-2-arachidonoyl- or linoleoyl-phosphatidylcholine or -phosphatidylethanolamine.... | |||
TMPK-00853 | ENPP1 Protein, Human, Recombinant (N-His) | Human | HEK293 Cells |
Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (eP... | |||
TMPK-00852 | ENPP1 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (eP... | |||
TMPH-00761 | Cutinase Protein, Fusarium solani subsp. Cucurbitae, Recombinant | Neocosmosporum cucurbitae | E. coli |
Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle. Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of the fungal infe... | |||
TMPH-03125 | Saposin-B-Val Protein, Pig, Recombinant (Flag & His) | Sus scrofa (Pig) | P. pastoris (Yeast) |
Saposin-B stimulates the hydrolysis of galacto-cerebroside sulfate by arylsulfatase A (EC 3.1.6.8), GM1 gangliosides by beta-galactosidase (EC 3.2.1.23) and globotriaosylceramide by alpha-galactosidase A (EC 3.2.1.22). S... | |||
TMPH-01298 | EPHX1 Protein, Human, Recombinant (His) | Human | E. coli |
Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Plays a role in the metabolism of endogenous lip... | |||
TMPY-03788 | ATP1B1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
ATP1B1 belongs to the family of Na+/K+and H+/K+-ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. ATP1B1 is a subunit of Na+/K+-ATPase. Na+/K+-ATPase is an integral membrane protein responsible for es... | |||
TMPH-00760 | Cutinase Protein, Fusarium solani subsp. Cucurbitae, Recombinant (His) | Neocosmosporum cucurbitae | P. pastoris (Yeast) |
Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle. Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of the fungal infe... | |||
TMPH-02575 | PDE5A Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP. Specifically regulates nitric-oxide-gen... | |||
TMPH-00424 | Cutinase Protein, Colletotrichum capsici, Recombinant (His & SUMO) | Colletotrichum capsici | E. coli |
Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle. Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of the fungal infe... | |||
TMPH-03448 | EHT1 Protein, S. cerevisiae, Recombinant (His) | Saccharomyces cerevisiae | E. coli |
Displays enzymatic activity both for medium-chain fatty acid (MCFA) ethyl ester synthesis and hydrolysis (esterase activity). MCFA are toxic for yeast and this enzyme could thus be involved in their detoxification by est... | |||
TMPH-00178 | AiiA Protein, Bacillus thuringiensis subsp., Recombinant (His & Myc) | Bacillus thuringiensis subsp. kurstaki | E. coli |
Catalyzes hydrolysis of N-hexanoyl-(S)-homoserine lactone, but not the R-enantiomer. Hydrolyzes short- and long-chain N-acyl homoserine lactones with or without 3-oxo substitution at C3, has maximum activity on C10-AHL. ... | |||
TMPH-00888 | APEH Protein, Human, Recombinant (His) | Human | E. coli |
This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and... | |||
TMPY-01742 | Acetylcholinesterase Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Acetylcholinesterase, also known as ACHE, is an enzyme that degrades (through its hydrolytic activity) the neurotransmitter acetylcholine, producing choline and an acetate group. Acetylcholinesterase plays a crucial role... | |||
TMPH-00159 | Subtilisin Carlsberg Protein, Bacillus licheniformis, Recombinant (His & SUMO) | Bacillus licheniformis | E. coli |
Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides (Ref.4, PubMed:11109488). Shows high specificity for aromatic and hydrophobic amino acids in the P1 subs... | |||
TMPH-03260 | Carboxypeptidase A1 Protein, Rat, Recombinant (His & Myc) | Rat | E. coli |
Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro. Catalyzes the conversion of leukotriene C4 to leukotriene F4 via the hydrolysis of ... | |||
TMPJ-00514 | ACPP Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Prostatic Acid Phosphatase (PAP) belongs to the histidine acid phosphatase family. PAP can catalyze the hydrolysis of member of phosphate monoestyers, including phosphorylated protein. PAP can high expression in metastas... | |||
TMPH-01325 | FAAH2 Protein, Human, Recombinant (His) | Human | E. coli |
Catalyzes the hydrolysis of endogenous amidated lipids like the sleep-inducing lipid oleamide ((9Z)-octadecenamide), the endocannabinoid anandamide (N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine), as well as other fatt... | |||
TMPJ-00876 | FAH Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Fumarylacetoacetase belongs to the FAH family. Fumarylacetoacetase is primary expressed in liver and kidney. It exists as a homodimer and catalyzes the hydrolysis of 4-fumarylacetoacetate into fumarate and acetoacetate. ... | |||
TMPJ-01057 | PSP Protein, Human, Recombinant (His) | Human | E. coli |
Phosphoserine phosphatase (PSP) is an enzyme that belongs to the serB family. PSPH catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphose... | |||
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カタログ番号 | 製品名 | ||
---|---|---|---|
L9600 | Peptide Compound Library | 791 compounds | |
791 peptides can be used in peptide drug development and signaling transduction and mechanism study; | |||
L7110 | Anti-Hypertension Compound Library | 678 compounds | |
678 hypertension-related small molecules for high-throughput and high-content screening. |