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天然化合物

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カタログ番号	製品名	別名	ターゲット
T4191	Multi-kinase inhibitor 1	Multi-kinase inhibitor I	Others , Bcr-Abl , PDGFR , c-Kit
	Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.		Others , Bcr-Abl , PDGFR , c-Kit
T72604	Multi-kinase-IN-1
	Multi-kinase-IN-1, a powerful kinase inhibitor, exhibits antitumor properties by inducing cell apoptosis. It is under investigation for its potential application in treating colorectal cancer.
T63870	Multi-kinase-IN-3
	Multi-kinase-IN-3 (compound 2) is a potent inhibitor of angiokinase and inhibits VEGFR-2 (IC50: 58.3 nM) and PDGFRβ (IC50: 55 nM).
T63967	Multi-kinase-IN-2
	Multi-kinase-IN-2 is an orally active inhibitor of angiokinases. multi-kinase-IN-2 significantly inhibits the activity of angiokinases such as VEGFR-1/2/3, PDGFRα/β, FGFR-1, LYN and c-KIT kinases. -IN-2 significantly att...
T77646	Multi-kinase-IN-5
	Multi-kinase-IN-5 (compound 15c) is a multi-kinase inhibitory agent that shows significant inhibition against a range of protein kinases including RET, KIT, cMet, VEGFR1, VEGFR2, FGFR1, PDGFR, and BRAF, with correspondin...
T81740	Multi-kinase-IN-6		Trk receptor
	Multi-kinase-IN-6 (compound 10e) is a multikinase inhibitor that effectively impedes the activity of TrkA, ALK2, c-KIT, EGFR, PIM1, CK2α, CHK1, and CDK2. It exhibits antiproliferative effects on MCF7, HCT116, and EKVX ca...		Trk receptor
T78792	Multi-kinase-IN-4		VEGFR
	Multi-kinase-IN-4 (compound 5d) is a multi-targeted kinase inhibitor active against VEGFR2, EGFR, HER2, and CDK2, with respective IC50 values of 0.33, 0.22, 0.18, and 2.09 μM. It exhibits broad-spectrum anti-cancer prope...		VEGFR
T81739	Multi-target kinase inhibitor 2		EGFR
	Compound 5K (Multi-target kinase inhibitor 2) is a multi-targeted kinase inhibitor demonstrating activity against EGFR, Her2, VEGFR2, and CDK2 with IC50 values between 40 to 204 nM. It exhibits cytotoxic effects on HepG2...		EGFR
T9014	SKI-178		Apoptosis , S1P Receptor
	SKI-178 is a sphingosine kinase 1 (SphK1) inhibitor with IC50 of 0.1-1.8 μM. It induces prolonged mitosis followed by apoptotic cell death through the intrinsic apoptotic cascade. The sustained activation of CDK1 during ...		Apoptosis , S1P Receptor
T6920	ON123300		FGFR , c-RET , JAK , CDK , PDGFR , Src , AMPK
	ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).		FGFR , c-RET , JAK , CDK , PDGFR , Src , AMPK
T2372	Ponatinib	AP24534	VEGFR , FGFR , Bcr-Abl , PDGFR , Src , c-Kit , Autophagy
	Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively).		VEGFR , FGFR , Bcr-Abl , PDGFR , Src , c-Kit , Autophagy
T6479	Dovitinib lactate hydrate	Dovitinib (TKI258) Lactate,Dovitinib Lactate,TKI258	VEGFR , FGFR , FLT , PDGFR , c-Kit
	Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) R...		VEGFR , FGFR , FLT , PDGFR , c-Kit
T1043	Multifungin	Bromochlorosalicylanilide,Salifungin	Others , Antifungal
	Multifungin (Bromochlorosalicylanilide) is an antifungal that studies oral candidiasis. It reduces the number of fungal populations in corn during storage and prevents the formation and accumulation of zearalenone.		Others , Antifungal
T22774L	Eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]（TFA)		Others
	eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species](TFA) is Elongation factor 1 subunit.eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) encodes an isoform of the alpha sub...		Others
TP2248	Ferritin heavy chain fragment [Multiple species]		Others
	Ferritin is a protein of 450 kDa consisting of 24 subunits that is present in every cell type. Invertebrates, these subunits are both the light (L) and the heavy (H) type with an apparent molecular weight of 19 kDA or 21...		Others
T36412	Multiflorenol
	Multiflorenol is a triterpene that has been found in T. kirilowii seeds.1 It inhibits in vitro activation of Epstein-Barr virus early antigen (EBV-EA) induced by the tumor promoter phorbol 12-myristate 13-acetate in a co...
T124593	Multinoside A
	Multinoside A is a useful organic compound for research related to life sciences. The catalog number is T124593 and the CAS number is 59262-54-3.
T39678	Multitarget AD inhibitor-1
	Multitarget AD inhibitor-1 is a reversible and selective inhibitor of butyrylcholinesterase (BuChE) with IC50 values of 7.22 μM and 1.55 μM for human BuChE (hBuChE) and equine serum BuChE (eqBuChE), respectively. Additio...
TP2269	MAP kinase fragment [Multiple species]		Others
	This Mitogen-activated protein kinase (MAP kinase) fragment has a peptide sequence of Lys-Tyr-Ile-His-Ser-Ala-Asn-Val-Leu. The MAP kinases are serine/threonine-specific protein kinases belonging to the CMGC (CDK/MAPK/GSK...		Others
T22774	Eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]		Others
	eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. ...		Others
T125342	Rosamultic acid
	Rosamultic acid is a useful organic compound for research related to life sciences and the catalog number is T125342.
T72013	Epigenetic Multiple Ligand
	Epigenetic Multiple Ligand is a cell-permeable inhibitor of substrate processing by several chromatin-associated enzymes, including SIRT1/2, H3/SET7, H3/p300/CBP, H4/RmtA, PABP1/CARM1, and H4/PRMT1. It acts by inducing e...
T74698	RMC-6236		Ras
	RMC-6236 is a RAS(ON)MULTI inhibitor with anticancer activity and is used in the study of advanced malignant solid tumors and colorectal cancer.		Ras
T14081	Enmetazobactam	AAI101	Antibacterial
	Enmetazobactam (AAI101) is an extended-spectrum β-lactamase inhibitor for the treatment of multi-drug resistant gram-negative bacterial infections.		Antibacterial
T10378	Artelinic acid		Parasite
	Artelinic acid is a water-soluble artemisinin analog with antimalarial activity and is used for the treatment of multi-drug resistant strains of Plasmodium falciparum.		Parasite
T27400L	Ganaplacide phosphate	Ganaplacide phosphate (1261113-96-5 Free base)	Others
	Ganaplacide phosphate exerts multi-stage antimalarial activity against Plasmodium symptomatic asexual blood-stage infections, and is able to prevent transmission and block infection in animal models.		Others
T6018	Zosuquidar trihydrochloride	Zosuquidar (LY335979) 3HCl,RS 33295-198 trihydrochloride,RS 33295-198 (D06387) 3HCl,Zosuquidar 3HCl,LY-335979 trihydrochloride	P-gp
	Zosuquidar trihydrochloride (LY-335979 trihydrochloride) is a potent modulator of P-glycoprotein-mediated multi-drug resistance with Ki of 60 nM. Phase 3.		P-gp
T1778	AT7519 Hydrochloride	AT7519 HCl,AT 7519 hydrochloride salt	Apoptosis , GSK-3 , CDK
	AT7519 Hydrochloride (AT7519 HCl) is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9.		Apoptosis , GSK-3 , CDK
T1836	AZD2932		VEGFR , FLT , PDGFR , c-Kit
	AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.		VEGFR , FLT , PDGFR , c-Kit
T20655	Polyquaternium-1	PQ-1,Polidronium chloride	Antibacterial
	Polyquaternium-1 (PQ-1) exerts strong bacteriostasis and little eye irritation and can be used as a polycationic ophthalmic preservative. Polyquaternium-1 inhibits the growth of microbial contaminants in multi-dose bottl...		Antibacterial
T2482	AT13148		ROCK , SGK , Akt , PKA , S6 Kinase
	AT13148 is an oral-active and ATP-competitive, multi-AGC kinase inhibitor for Akt1/2/3, p70S6K, PKA, and ROCKI/II.		ROCK , SGK , Akt , PKA , S6 Kinase
T11641	N-Desmethyl imatinib	Imatinib metabolite N-Desmethyl imatinib,Norimatinib	Bcr-Abl , PDGFR , c-Kit , Drug Metabolite
	N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.		Bcr-Abl , PDGFR , c-Kit , Drug Metabolite
T7945	SU14813		VEGFR , PDGFR , c-Kit
	SU14813 is a multi-receptor tyrosine kinase inhibitor with potent antiangiogenesis and antitumor activity (IC50s of 50, 2, 4, 15 nM for VEGFR2, VEGFR1, PDGFRβ and KIT).		VEGFR , PDGFR , c-Kit
T17267	XL228		IGF-1R , Bcr-Abl , Src , Aurora Kinase
	XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).		IGF-1R , Bcr-Abl , Src , Aurora Kinase
T2358	ENMD-2076		Apoptosis , VEGFR , FGFR , FLT , c-RET , PDGFR , Src , Aurora Kinase
	ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.
T5466	Tyrosine kinase-IN-1		VEGFR , FGFR , FLT , PDGFR
	Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor（KDR, Flt-1, FGFR1 and PDGFRα with IC50s of 4nM, 20nM, 4nM, 2 nM ,respectively）		VEGFR , FGFR , FLT , PDGFR
T6996	SU 5402	SU5402	VEGFR , FGFR , PDGFR
	SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.		VEGFR , FGFR , PDGFR
TQ0166	Tesevatinib	KD-019,XL-647,EXEL-7647	EGFR , VEGFR , FLT , Ephrin Receptor
	Tesevatinib (XL-647) is an orally available, multi-target tyrosine kinase inhibitor (IC50s: 0.3, 16, 1.5, 8.7, and 1.4 nM for EGFR, ErbB2, KDR, Flt4, and EphB4).		EGFR , VEGFR , FLT , Ephrin Receptor
T11427	Antibacterial compound 2		Antifungal
			Antifungal
T3476	JI-101	CGI-1842,JI 101	VEGFR , PDGFR , Ephrin Receptor
	JI-101 (CGI-1842) is an oral multi-kinase inhibitor that targets vascular endothelial growth factor receptor type 2 (VEGFR-2), platelet derived growth factor receptor β (PDGFR-β), and ephrin type-B receptor 4 (EphB4).		VEGFR , PDGFR , Ephrin Receptor
T3068	AT9283	J-504568	Apoptosis , FLT , JAK , Bcr-Abl , Aurora Kinase , Autophagy
	AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).		Apoptosis , FLT , JAK , Bcr-Abl , Aurora Kinase , Autophagy
T72437	PARP1/2/TNKS1/2-IN-1		Apoptosis , PARP , Wnt/beta-catenin
	PARP1/2/TNKS1/2-IN-1 is a multi-target inhibitor of PARP-1, PARP-2, TNKS1 and TNKS2.PARP1/2/TNKS1/2-IN-1 has potential anti-tumor activity and induces apoptosis.		Apoptosis , PARP , Wnt/beta-catenin
T83979	Sulcardine 2HCl	Sulcardine 2HCl（343935-60-4 Free base）,HBI-3000 2HCl	HER , Sodium Channel
	Sulcardine 2HCl is a multi-ion channel blocker with antiarrhythmic effects that blocks the properties of hERG and hNav1.5 channels and can be used to study atrial fibrillation and ventricular arrhythmias.		HER , Sodium Channel
T10157	Regorafénib N-oxyde (M2)		Raf , VEGFR , c-RET , PDGFR , c-Kit , Drug Metabolite
	Regorafénib N-oxyde M2 is an active metabolite of Regorafenib. Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, RET, Kit, and Raf-1 (IC50s: 13/4.2/46, 1.5, 22, 7, and 2.5 nM).		Raf , VEGFR , c-RET , PDGFR , c-Kit , Drug Metabolite
T77758	AChE/BuChE-IN-4		AChE
	AChE/BuChE-IN-4 is a multi-target AChE/BuChE inhibitor with oral activity and blood-brain barrier permeability, with IC50 values of 2.08 and 7.41 μM for AChE and BuChE, respectively.		AChE
T0331L	Moxifloxacin	Avelox,Moxeza	Others , Antibacterial , Antibiotic
	Moxifloxacin (Avelox) is a fourth-generation fluoroquinolone that has been shown to be effective against Gram-positive, Gram-negative, and atypical strains, as well as multi-drug resistant Streptococcus pneumoniae.		Others , Antibacterial , Antibiotic
T2415	PP121		Apoptosis , VEGFR , Bcr-Abl , PDGFR , Src , mTOR , Hck
	PP-121 is a multi-targeted inhibitor of PDGFR (IC50: 2 nM), Hck (IC50: 8 nM), mTOR (IC50: 10 nM), VEGFR2(IC50: 12 nM), Src (IC50: 14 nM) and Abl (IC50: 18 nM) , also inhibits DNA-PK (IC50: 60 nM).		Apoptosis , VEGFR , Bcr-Abl , PDGFR , Src , mTOR , Hck
T2586	Cabozantinib	XL184,BMS-907351	Apoptosis , VEGFR , FLT , c-Met/HGFR , c-RET , TAM Receptor , c-Kit
	Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM). Cabozantinib exhibits both antitumor and antiangiogenic activity...
T6104	Cerdulatinib hydrochloride	Cerdulatinib,PRT2070,PRT062070 hydrochloride,PRT062070,PRT2070 hydrochloride	MLK , c-Fms , Tyrosine Kinases , Hippo pathway , JAK , Syk
	Cerdulatinib hydrochloride (PRT2070 hydrochloride) is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for JAK1/JAK2/JAK3/TYK2 and Syk, respectively. Also inhibits 19...		MLK , c-Fms , Tyrosine Kinases , Hippo pathway , JAK , Syk
T1895	SKLB 610		VEGFR , FGFR , PDGFR
	SKLB610, a novel multi-targeted inhibitor, inhibits angiogenesis-related tyrosine kinase VEGFR2, FGFR2, and PDGFR at a rate of 97%, 65%, and 55%, respectively, at the concentration of 10 μM in biochemical kinase assays.		VEGFR , FGFR , PDGFR

Compounds

Multi-kinase inhibitor 1

T4191

Synonym: Multi-kinase inhibitor I

Target: Others, Bcr-Abl, PDGFR, c-Kit

Multi-target kinase inhibitor 2

Target: Apoptosis, S1P Receptor

ON123300

T6920

Synonym:

Target: FGFR, c-RET, JAK, CDK, PDGFR, Src, AMPK

Ponatinib

T2372

Synonym: AP24534

Target: VEGFR, FGFR, Bcr-Abl, PDGFR, Src, c-Kit, Autophagy

Dovitinib lactate hydrate

T6479

Synonym: Dovitinib (TKI258) Lactate,Dovitinib Lactate,TKI258

Target: VEGFR, FGFR, FLT, PDGFR, c-Kit

Multifungin

T1043

Synonym: Bromochlorosalicylanilide,Salifungin

Target: Others, Antifungal

eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]（TFA)

T22774L

Synonym:

Target: Others

ferritin heavy chain fragment [Multiple species]

Multitarget AD inhibitor-1

T39678

Synonym:

Target:

MAP kinase fragment [Multiple species]

TP2269

Synonym:

Target: Others

eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]

Epigenetic Multiple Ligand

Target: Antibacterial

Ganaplacide phosphate

T27400L

Synonym: Ganaplacide phosphate (1261113-96-5 Free base)

Target: Others

Zosuquidar trihydrochloride

T6018

Synonym: Zosuquidar (LY335979) 3HCl,RS 33295-198 trihydrochloride,RS 33295-198 (D06387) 3HCl,Zosuquidar 3HCl,LY-335979 trihydrochloride

Target: P-gp

AT7519 Hydrochloride

T1778

Synonym: AT7519 HCl,AT 7519 hydrochloride salt

Target: Apoptosis, GSK-3, CDK

AZD2932

T1836

Synonym:

Target: VEGFR, FLT, PDGFR, c-Kit

Polyquaternium-1

T20655

Synonym: PQ-1,Polidronium chloride

Target: Antibacterial

AT13148

T2482

Synonym:

Target: ROCK, SGK, Akt, PKA, S6 Kinase

N-Desmethyl imatinib

T11641

Synonym: Imatinib metabolite N-Desmethyl imatinib,Norimatinib

Target: Bcr-Abl, PDGFR, c-Kit, Drug Metabolite

SU14813

T7945

Synonym:

Target: VEGFR, PDGFR, c-Kit

XL228

T17267

Synonym:

Target: IGF-1R, Bcr-Abl, Src, Aurora Kinase

ENMD-2076

T2358

Synonym:

Target: Apoptosis, VEGFR, FGFR, FLT, c-RET, PDGFR, Src, Aurora Kinase

Tyrosine kinase-IN-1

T5466

Synonym:

Target: VEGFR, FGFR, FLT, PDGFR

SU 5402

T6996

Synonym: SU5402

Target: VEGFR, FGFR, PDGFR

Tesevatinib

TQ0166

Synonym: KD-019,XL-647,EXEL-7647

Target: EGFR, VEGFR, FLT, Ephrin Receptor

Antibacterial compound 2

Synonym: CGI-1842,JI 101

Target: VEGFR, PDGFR, Ephrin Receptor

AT9283

T3068

Synonym: J-504568

Target: Apoptosis, FLT, JAK, Bcr-Abl, Aurora Kinase, Autophagy

PARP1/2/TNKS1/2-IN-1

T72437

Synonym:

Target: Apoptosis, PARP, Wnt/beta-catenin

Sulcardine 2HCl

T83979

Synonym: Sulcardine 2HCl（343935-60-4 Free base）,HBI-3000 2HCl

Target: HER, Sodium Channel

Regorafénib N-oxyde (M2)

T10157

Synonym:

Target: Raf, VEGFR, c-RET, PDGFR, c-Kit, Drug Metabolite

Synonym: Avelox,Moxeza

Target: Others, Antibacterial, Antibiotic

PP121

T2415

Synonym:

Target: Apoptosis, VEGFR, Bcr-Abl, PDGFR, Src, mTOR, Hck

Cabozantinib

T2586

Synonym: XL184,BMS-907351

Target: Apoptosis, VEGFR, FLT, c-Met/HGFR, c-RET, TAM Receptor, c-Kit

Cerdulatinib hydrochloride

T6104

Synonym: Cerdulatinib,PRT2070,PRT062070 hydrochloride,PRT062070,PRT2070 hydrochloride

Target: MLK, c-Fms, Tyrosine Kinases, Hippo pathway, JAK, Syk

SKLB 610

T1895

Synonym:

Target: VEGFR, FGFR, PDGFR

カタログ番号	製品名	別名	ターゲット
T5783	Rosamultin		Antioxidant , HIV Protease
	Rosamultin has antioxidant, antiinflammatory/antinociceptive properties,and has anti-human immunodeficiency virus (HIV) activity.		Antioxidant , HIV Protease
TN5751	Garcimultiflorone J
	Garcimultiflorone J is a natural product for research related to life sciences. The catalog number is TN5751 and the CAS number is 2010216-41-6.
T80000	Multiflorin B		NO Synthase
	Multiflorin B (compound 5), a kaempferol glycoside, can be extracted from the root of Neocheiropteris palmatopedata. This compound demonstrates the ability to inhibit nitric oxide production, achieving a 52% inhibition a...		NO Synthase
TN3637	Chloramultilide B		Antifection
	Chloramultilide B exhibits moderate in vitro antifungal activity.		Antifection
TN5563	Multifloroside
	Multifloroside is a natural product for research related to life sciences. The catalog number is TN5563 and the CAS number is 131836-10-7.
TN3639	Chloramultilide D		Others
	Chloramultilide D is a natural product from Chloranthus spicatus.		Others
TN3638	Chloramultilide C		Others
	Chloramultilide C is a natural product of Chloranthus, Chloranthaceae. The catalog number is TN3638 and the CAS number is 1000995-48-1. Chloramultilide C can be used as a reference standard.		Others
T81741	Multiflorin A
	Multiflorin A, an active compound extracted from Pruni semen, exhibits laxative properties and hinders intestinal glucose absorption while facilitating bacterial metabolism [1].
TN6916	multiflorin
	multiflorin is a natural product.
TN1959	Multicaulisin		Others
	Multicaulisin is a natural product from Morus multicaulis.		Others
TQ0152	Dalfopristin	RP54476	Antibacterial , Antibiotic
	Dalfopristin (RP54476) is a semi-synthetic streptogramin antibiotic. Quinupristin/Dalfopristin (Q/D) is used for the treatment of multi-drug resistant Enterococcus faecium infections.		Antibacterial , Antibiotic
TN2213	Imperialine 3-β-D-glucoside	Sipeimine-3-beta-D-glucoside	Others
	Imperialine 3-β-D-glucoside (Sipeimine-3-beta-D-glucoside) is a natural product. Imperialine 3-β-D-glucoside may exhibit anti-tumor properties against multi-drug resistant tumor cells.		Others
T6S1294	Nicotiflorin	Nictoflorin,Kaempferol-3-O-Rutinoside,Nicotifloroside	Others
	1. Nicotiflorin (Kaempferol-3-O-Rutinoside) has potential therapeutic effects on cerebral ischemic illness. 2. Nicotiflorin has protective effects on reducing memory dysfunction, energy metabolism failure and oxidative s...		Others
TN1403	Arjunolic acid		IL Receptor , TNF , Reactive Oxygen Species , JNK , AChE
	Arjunolic acid has antioxidant, anti-inflammatory, antinociceptive and anticholinesterasic (AChE and BuChE) activities, it may as promising targets for the development of innovative multi-functional medicines for Alzheim...		IL Receptor , TNF , Reactive Oxygen Species , JNK , AChE
TN5263	1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one	Xanthohumol	Apoptosis , BCL , PARP , HCV Protease , IAP , Caspase , HIV Protease , NMDAR , p53
	1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one (Xanthohumol) , prenylchacone flavonoid, is a natural product with multi-biofunctions purified from Hops Humulus lupulus,is e...
T5089	5-Aminovaleric acid		Others , Endogenous Metabolite
	5-aminovalerate (or 5-aminopentanoic acid) is a lysine degradation product. It can be produced both endogenously or through bacterial catabolism of lysine. 5-aminovalerate is formed via the following multi-step reaction:...		Others , Endogenous Metabolite
TN1397	Ardisiacrispin B		Others
	Ardisiacrispin B displays cytotoxic effects in multi-factorial drug resistant cancer cells via ferroptotic and apoptotic cell death.		Others
TN2726	Jatrophane 5		P-gp
	Jatrophane 5 demonstrates the most powerful inhibition of P-gp, higher than R(+)-verapamil and tariquidar in colorectal multi-drug resistant (MDR) cells (DLD1-TxR).		P-gp
TN3911	Ecdysterone 2,3:20,22-diacetonide		Others
	Due to the multi-drug resistance reversal activity of the less polar ecdysteroids, several new products( including 20-hydroxyecdysone,20-hydroxyecdysone 2,3;20,22-diacetonide) are promising for being tested against vario...		Others
T72733	Geissoschizoline	(+)-Geissoschizoline
	Geissoschizoline ((+)-Geissoschizoline), with IC50 values of 20.40 µM for human AChE and 10.21 µM for BChE, functions as a potent inhibitor and emerges as a promising multi-target prototype for research into preventing n...
TN2727	Jatrophane 2		P-gp , Antifection
	2,5,7,8,9,14-Hexaacetoxy-3-benzoyloxy-15-hydroxyjatropha-6(17),11E-diene (Jatrophane 2 ) exhibits significant antifeedant activity against a generalist plant-feeding insect, the cotton bollworm (Helicoverpa armigera). Ja...		P-gp , Antifection

天然物製品

Rosamultin

T5783

Synonym:

Target: Antioxidant, HIV Protease

Target: Antibacterial, Antibiotic

Imperialine 3-β-D-glucoside

TN2213

Synonym: Sipeimine-3-beta-D-glucoside

Target: Others

Nicotiflorin

T6S1294

Synonym: Nictoflorin,Kaempferol-3-O-Rutinoside,Nicotifloroside

Target: IL Receptor, TNF, Reactive Oxygen Species, JNK, AChE

1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one

TN5263

Synonym: Xanthohumol

Target: Apoptosis, BCL, PARP, HCV Protease, IAP, Caspase, HIV Protease, NMDAR, p53

5-Aminovaleric acid

T5089

Synonym:

Target: Others, Endogenous Metabolite

Ecdysterone 2,3:20,22-diacetonide

Synonym: (+)-Geissoschizoline

Target: P-gp, Antifection

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-00095	IL-3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IL-3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.5 kDa and the accession number is P08700.
TMPY-00297	IL-3 Protein, Human, Recombinant(aa 20-152)	Human	E. coli
	IL-3 Protein, Human, Recombinant(aa 20-152) is expressed in E. coli expression system. The predicted molecular weight is 15.2 kDa and the accession number is P08700.
TMPK-00590	IL-3 Protein, Human, Recombinant (E. coli)	Human	E. coli
	Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit...
TMPK-00049	IL-3 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit...
TMPK-00655	IL-3 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	E. coli
	Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit...
TMPK-00033	IL-3 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit...
TMPK-00031	IL-3 Protein, Human, Recombinant (His & Avi)	Human	E. coli
	Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit...
TMPK-00032	IL-3 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	E. coli
	Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit...
TMPY-01355	Transglutaminase 2/TGM2 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Protein-glutamine gamma-glutamyltransferase 2, also known as Tissue transglutaminase, Transglutaminase C, Transglutaminase-2, and TGM2, is a member of the transglutaminase superfamily. TGM2 plays a role in cell growth an...
TMPJ-00375	HGF Protein, Human, Recombinant (His)	Human	HEK293 Cells
	HGF, is a pleiotropic protein in the Plasminogen subfamily of S1 peptidases and contains 4 kringle domains, 1 PAN domain and 1 peptidase S1 domain. HGF is secreted as an inactive 728 amino acid (aa) single chain propepti...
TMPJ-00051	IL-3 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit...
TMPJ-00783	Apolipoprotein D/APOD Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Apolipoprotein-D (ApoD) is an atypical apolipoprotein and, based on its primary structure, it also a member of the lipocalin family. ApoD is mainly associated with high density lipoproteins in human plasma. ApoD is expre...
TMPY-01484	THSD1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Thrombospondin type-1 domain-containing protein 1, also known as transmembrane molecule with thrombospondin module, THSD1 and TMTSP, is a single-pass type I membrane protein that contains one TSP type-1 domain. THSD1 is ...
TMPH-02153	Sulfiredoxin-1 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduct...
TMPH-01076	CEMP1 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	May play a role in development of the periodontium which surrounds and supports the teeth by promoting the differentiation of multi-potent cells from the periodontal ligament into cementoblasts to form the cementum. Bind...
TMPH-01299	EMC4 Protein, Human, Recombinant (His)	Human	E. coli
	Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. Preferentially accommodates prot...
TMPH-02185	TEP1 Protein, Human, Recombinant (His)	Human	E. coli
	Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini. Also component of the ribonucleoprotein vaults particle, a multi-subunit structure involved in nucleo-cyt...
TMPK-00109	Artemin Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Artemin (ARTN) is a member of glial cell line-derived neurotrophic factor (GDNF) family of ligands, and its signaling is mediated via a multi-component receptor complex including the glycosylphosphatidylinositol-anchored...
TMPY-03458	Sorcin/SRI Protein, Human, Recombinant	Human	Baculovirus Insect Cells
	Sorcin was originally identified in multidrug-resistant cells. It is a calcium-binding protein. Sorcin modulates excitation-contraction coupling in the heart, contributes to calcium homeostasis in the heart sarcoplasmic ...
TMPY-03267	Sorcin/SRI Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Sorcin was originally identified in multidrug-resistant cells. It is a calcium-binding protein. Sorcin modulates excitation-contraction coupling in the heart, contributes to calcium homeostasis in the heart sarcoplasmic ...
TMPJ-00507	EIF4E Protein, Human, Recombinant	Human	E. coli
	Eukaryotic translation initiation factor 4E is a 217 amino acids protein that belongs to the eukaryotic initiation factor 4E family. eIF4F is a multi-subunit complex, the composition of which varies with external and int...
TMPJ-00111	CD9 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	CD9, also known as Tspan29, 5H9 antigen, Leukocyte antigen MIC3 (MIC3), Motility-related protein, is a multi-pass membrane protein which belongs to the tetraspanin (TM4SF) family or the transmembrane 4 superfamily. CD9 i...
TMPY-03609	ATP5D Protein, Human, Recombinant (His)	Human	E. coli
	ATP5D is a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synth...
TMPY-03511	COX5B Protein, Human, Recombinant (His)	Human	E. coli
	Cytochrome C oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contribut...
TMPJ-00812	HBQ1 Protein, Human, Recombinant (His)	Human	E. coli
	Hemoglobin subunit theta-1 is a protein that in humans is encoded by the HBQ1 gene. Theta-globin mRNA is originally found in human fetal erythroid tissue but not in adult erythroid or other nonerythroid tissue. Theta-1 i...
TMPH-00536	Epstein-Barr virus (strain AG876) EBNA2 Protein (His & Myc)	EBV	P. pastoris (Yeast)
	Plays a key role in the activation of the host resting B-cell and stimulation of B-cell proliferation. Acts by up-regulating the expression of viral EBNA1-6, LMP1, LMP2A and LMP2B genes, as well as several host genes inc...
TMPJ-00298	CD36 Protein, Human, Recombinant (aa 27-432, His)	Human	HEK293 Cells
	Scavenger Receptor Class B Member 2 (SCARB2) is a type III multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far examined. Earlie...
TMPY-02236	PTH1R Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Parathyroid hormone / parathyroid hormone-related peptide receptor, also known as PTH / PTHrP type I receptor, PTH/PTHr receptor, Parathyroid hormone 1 receptor, PTH1 receptor, PTH1R and PTHR, is a multi-pass membrane pr...
TMPJ-00299	LIMPII/SR-B2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Lysosome membrane protein II (LIMPII)，also known as SCARB2, is a type III multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far e...
TMPY-01480	LTC4S Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Leukotriene C4 synthase, also known as LTC4 synthase, Leukotriene-C(4) synthase, and LTC4S, is a multi-pass membrane protein that belongs to the MAPEG family. LTC4S is detected in the lung, platelets, and the myelogenous...
TMPY-01479	SPG3A Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	Atlastin-1, also known as Spastic paraplegia 3 protein A, Guanine nucleotide-binding protein 3, GTP-binding protein 3, GBP3, ATL1 and SPG3A, is a multi-pass membrane protein which belongs to theGBP family and atlastin...
TMPY-02001	RTN4 Protein, Human, Recombinant (GST)	Human	E. coli
	Reticulon-4, also known as Foocen, Neurite outgrowth inhibitor, Nogo protein, Neuroendocrine-specific protein, Neuroendocrine-specific protein C homolog, RTN-x, Reticulon-5 and RTN4, is a multi-pass membrane protein that...
TMPY-01576	Artemin Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Artemin (ARTN) is a member of glial cell line-derived neurotrophic factor (GDNF) family of ligands, and its signaling is mediated via a multi-component receptor complex including the glycosylphosphatidylinositol-anchored...

IL-3 Protein, Human, Recombinant (His)

TMPY-00095

Species: Human

Expression System: HEK293 Cells

IL-3 Protein, Human, Recombinant(aa 20-152)

TMPY-00297

Species: Human

Expression System: E. coli

IL-3 Protein, Human, Recombinant (E. coli)

TMPK-00590

Species: Human

Expression System: E. coli

IL-3 Protein, Mouse, Recombinant (hFc)

TMPK-00049

Species: Mouse

Expression System: HEK293 Cells

IL-3 Protein, Cynomolgus, Recombinant (His)

TMPK-00655

Species: Cynomolgus

Expression System: E. coli

IL-3 Protein, Human, Recombinant (hFc)

TMPK-00033

Species: Human

Expression System: HEK293 Cells

IL-3 Protein, Human, Recombinant (His & Avi)

TMPK-00031

Species: Human

Expression System: E. coli

IL-3 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00032

Species: Human

Expression System: E. coli

Transglutaminase 2/TGM2 Protein, Human, Recombinant (His)

TMPY-01355

Species: Human

Expression System: Baculovirus Insect Cells

HGF Protein, Human, Recombinant (His)

TMPJ-00375

Species: Human

Expression System: HEK293 Cells

IL-3 Protein, Mouse, Recombinant (His)

TMPJ-00051

Species: Mouse

Expression System: HEK293 Cells

Apolipoprotein D/APOD Protein, Human, Recombinant (His)

TMPJ-00783

Species: Human

Expression System: HEK293 Cells

THSD1 Protein, Mouse, Recombinant (His)

TMPY-01484

Species: Mouse

Expression System: HEK293 Cells

Sulfiredoxin-1 Protein, Human, Recombinant (His & Myc)

TMPH-02153

Species: Human

Expression System: E. coli

CEMP1 Protein, Human, Recombinant (His)

TMPH-01076

Species: Human

Expression System: P. pastoris (Yeast)

EMC4 Protein, Human, Recombinant (His)

TMPH-01299

Species: Human

Expression System: E. coli

TEP1 Protein, Human, Recombinant (His)

TMPH-02185

Species: Human

Expression System: E. coli

Artemin Protein, Human, Recombinant (hFc)

TMPK-00109

Species: Human

Expression System: HEK293 Cells

Sorcin/SRI Protein, Human, Recombinant

TMPY-03458

Species: Human

Expression System: Baculovirus Insect Cells

Sorcin/SRI Protein, Human, Recombinant (His & GST)

TMPY-03267

Species: Human

Expression System: Baculovirus Insect Cells

EIF4E Protein, Human, Recombinant

TMPJ-00507

Species: Human

Expression System: E. coli

CD9 Protein, Human, Recombinant (hFc)

TMPJ-00111

Species: Human

Expression System: HEK293 Cells

ATP5D Protein, Human, Recombinant (His)

TMPY-03609

Species: Human

Expression System: E. coli

COX5B Protein, Human, Recombinant (His)

TMPY-03511

Species: Human

Expression System: E. coli

HBQ1 Protein, Human, Recombinant (His)

TMPJ-00812

Species: Human

Expression System: E. coli

Epstein-Barr virus (strain AG876) EBNA2 Protein (His & Myc)

TMPH-00536

Species: EBV

Expression System: P. pastoris (Yeast)

CD36 Protein, Human, Recombinant (aa 27-432, His)

TMPJ-00298

Species: Human

Expression System: HEK293 Cells

PTH1R Protein, Human, Recombinant (His)

TMPY-02236

Species: Human

Expression System: HEK293 Cells

LIMPII/SR-B2 Protein, Mouse, Recombinant (hFc)

TMPJ-00299

Species: Mouse

Expression System: HEK293 Cells

LTC4S Protein, Human, Recombinant (His)

TMPY-01480

Species: Human

Expression System: Baculovirus Insect Cells

SPG3A Protein, Human, Recombinant (GST)

TMPY-01479

Species: Human

Expression System: Baculovirus Insect Cells

RTN4 Protein, Human, Recombinant (GST)

TMPY-02001

Species: Human

Expression System: E. coli

Artemin Protein, Mouse, Recombinant (hFc)

TMPY-01576

Species: Mouse

Expression System: HEK293 Cells

カタログ番号	製品名
L7850	High Solubility 3D Diversity Fragment Library	1079 compounds
	The library of highly soluble 3D structural diversity fragments contains 1079 compounds.
L6720	Anti-COVID-19 Traditional Chinese Medicine Compound Library	1147 compounds
	A unique collection of 1147 monomers from 60 TCM plants, a powerful tool for anti-COVID-19 drug discovery, can be used for HTS and HCS screening；
L9700	Endoplasmic Reticulum Stress Compound Library	193 compounds
	A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS);
L7100	Anti-Obesity Compound Library	2247 compounds
	A unique collection of 2247 anti-obesity compounds for high throughput and high content screening;

ライブラリー

High Solubility 3D Diversity Fragment Library

L7850

Compounds: 1079

Anti-COVID-19 Traditional Chinese Medicine Compound Library

L6720

Compounds: 1147

Endoplasmic Reticulum Stress Compound Library

L9700

Compounds: 193

Anti-Obesity Compound Library

L7100

Compounds: 2247