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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T21331 | SAR-020106 | Chk | |
SAR-020106 is a potent, ATP-competitive, and selective CHK1 inhibitor with an IC50 of 13.3 nmol/L on the isolated human enzyme. | |||
T4210 | SAR-20347 | SAR20347 | Tyrosine Kinases , JAK |
SAR-20347 is an inhibitor of TYK2, JAK1/2/3 (IC50: 0.6/23/26/41 nM). | |||
T16841 | SAR-260301 | PI3K | |
SAR-260301 is an orally available and selective inhibitor of PI3Kβ (IC50: 23 nM). | |||
T35834L | (Sar¹)-Angiotensin II acetate | RAAS | |
(Sar¹)-Angiotensin II acetate, an analogue of Angiotensin II, is a specific agonist of angiotensin AT1 receptor. It binds to brain membrane-rich particles, with a Kd of 2.7 nM. It can stimulate protein synthesis and cell... | |||
T6012 | SAR131675 | SAR 131675 | VEGFR |
SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM. | |||
TP1917L1 | Sar-[D-Phe8]-des-Arg9-Bradykinin acetate | Sar-[D-Phe8]-des-Arg9-Bradykinin acetate(126959-88-4 free base) | Bradykinin Receptor |
Sar-[D-Phe8]-des-Arg9-Bradykinin acetate is a potent and selective bradykinin B1 receptor agonist (EC50 = 9.02 nM in rabbit aorta) that is resistant to aminopeptidase, kininase I and II (ACE) and neutral endopeptidase cl... | |||
T28659 | SAR-7226 Hydrate | SAR7226,SAR 7226,SAR-7226 | |
SAR-7226 Hydrate, a SGLT1/2 inhibitor, is used potentially for the treatment of type 2 diabetes. | |||
T70652 | SAR-104772 | ||
SAR-104772 is a novel inhibitor of TAFIa (activated thrombin-activatable fibrinolysis inhibitor). | |||
T13666 | Dupilumab | REGN-668,SAR-231893 | IL Receptor |
Dupilumab (REGN-668) is a systemic immunomodulator for AD. Dupilumab is a fully human monoclonal antibody against the alpha subunit of the interleukin-4 receptor, which inhibits downstream signaling of IL-4 and IL-13 and... | |||
T4521 | Edg-2 receptor inhibitor 1 | SAR-100842 | LPA Receptor |
Edg-2 receptor inhibitor 1 (SAR-100842) is an Edg-2 receptor inhibitor extracted (IC50: <0.1 μM). | |||
T76750 | Cemiplimab | REGN-2810,SAR-439684 | Others |
Cemiplimab (Anti-Human PD-1) is a human monoclonal antibody against programmed cell death receptor 1 (PD-1) and a checkpoint inhibitor that blocks PD-1/PD-L1 mediated T-cell inhibition and can be used in metastatic cance... | |||
T15050 | Danicamtiv | MYK-491,SAR 440181 | Myosin |
Danicamtiv (MYK-491) is an inotropic agent and it also is a selective allosteric activator of cardiac myosin. Danicamtiv increases cardiac systolic function and preserves mechanical efficiency. | |||
T77045 | Itepekimab | REGN-3500,SAR-440340 | Others |
Itepekimab (REGN-3500) is a potent monoclonal antibody against IL-33.Itepekimab reduces airway inflammation and associated tissue damage in in vivo experiments and can be used to study asthma. | |||
T36759 | SAR 216471 hydrochloride | ||
Potent P2Y12 antagonist (IC50 = 17 nM). Displays antiplatelet and antithrombotic activity in vivo. Orally available. Boldron et al (2014) N-[6-(4-butanoyl-5-methyl-1H-pyrazol-1-yl)pyridazin-3-yl]-5-chloro-1-[2-(4-methylp... | |||
T39023 | Biotin-sar-oh | ||
Biotin-sar-oh is a cleavable linker vital in ADC synthesis. Biotin-sar-oh joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimiz... | |||
T38951 | Isatuximab | SAR-650984,hu38SB19,Isatuximab-irfc | Apoptosis , CD38 |
Isatuximab is a monoclonal antibody targeting the transmembrane receptor and extracellular enzyme CD38 in malignant cells of the hematological system and is a highly expressed protein in multiple myeloma. Isatuximab has ... | |||
T76722 | Sarilumab | REGN-88,SAR-153191 | IL Receptor |
Sarilumab (SAR-153191)is a potent interleukin-6 IL-6 receptor antagonist and a human immunoglobulin G1 monoclonal antibody. Sarilumab inhibits IL-6-mediated signaling and reduces inflammation.Sarilumab is used for the pr... | |||
T28658 | SAR-114137 | ||
SAR-114137 is an inhibitor of cysteine cathepsin with oral activity. | |||
T1995 | Fedratinib | TG-101348,SAR 302503 | Apoptosis , FLT , c-RET , JAK |
Fedratinib (TG-101348) (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent activity against JAK3. | |||
T3977 | Lifitegrast | SHP-606,SAR 1118 | Integrin |
Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist. | |||
T6131 | Pimasertib | AS703026,MSC1936369B,SAR 245509 | MEK |
Pimasertib (AS703026) is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity. | |||
T35834 | (Sar1)-Angiotensin II | (Sar¹)-Angiotensin II | |
The substitution with Sar at position 1 of angiotensin II resulted in a partial agonistic activity. | |||
T9251 | Fedratinib hydrochloride hydrate | TG-101348 hydrochloride hydrate,SAR 302503 hydrochloride hydrate | Apoptosis , JAK |
Fedratinib hydrochloride hydrate (SAR 302503 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor. | |||
TP1917 | Sar-[D-Phe8]-des-Arg9-Bradykinin | ||
Potent and selective bradykinin B1 receptor agonist (EC50 = 9.02 nM in rabbit aorta) that is resistant to aminopeptidase, kininase I and II (ACE) and neutral endopeptidase cleavage. Exhibits hypotensive and angiogenic ac... | |||
T29834 | Albitiazolium bromide | SAR 97276,SAR97276,SAR-97276 | |
Albitiazolium bromide( SAR 972760 is a choline analog that is evaluating in clinical trials (phase II) for severe malaria. | |||
T24758 | SAR127303 | SAR-127303,SAR 127303 | |
SAR127303 is an effective covalent inhibitor of MAGL. SAR127303 behaves as a selective and competitive inhibitor of mouse and human MAGL. | |||
T66699 | Fmoc-Sar-OH | ||
Fmoc-Sar-OH is a useful organic compound for research related to life sciences. The catalog number is T66699 and the CAS number is 77128-70-2. | |||
T5467 | SAR125844 | SAR125884 | Apoptosis , c-Met/HGFR |
SAR125844, a potent and highly selective inhibitor of the MET receptor tyrosine kinase (RTK), for intravenous administration. (IC50 value of 4.2 nmol/L) | |||
T12849L | SAR7334 hydrochloride | Others | |
SAR7334 hydrochloride is a potent and specific inhibitor of TRPC6(IC50 of 7.9 nM). | |||
T12831L | SAR405 | PI3K , Autophagy | |
SAR-405 is a potent and selective PIK3C3/Vps34 inhibitor (IC50:1.2 nM; Kd:1.5 nM) that prevents autophagy and synergizes with MTOR inhibition in tumor cells. SAR405 treatment also inhibits autophagy induced either by sta... | |||
T7391 | SAR407899 | ROCK , Rho | |
SAR407899 is Rho kinase inhibitor potently inhibits endothelin-1-induced constriction of renal resistance arteries. | |||
T34521 | SAR629 | SAR 629,SAR-629 | |
SAR-629 is an MGL inhibitor or 2-AG degradation inhibitor. | |||
T32602 | Laurylsarcosyltaurine | Lauryl-sar-taurine | |
Laurylsarcosyltaurine is a surface active constituent of crab gastric juice. | |||
T12849 | SAR7334 | TRCP6-IN-1 | TRP/TRPV Channel |
T39056 | Atuzabrutinib | SAR 444727,PRN473 | |
Atuzabrutinib is a potent BTK (Bruton's tyrosine kinase) inhibitor. | |||
T12832 | Amcenestrant | SAR439859 | Estrogen Receptor/ERR , Estrogen/progestogen Receptor |
Amcenestrant (SAR439859) is an orally active, nonsteroidal and selective degrader of estrogen receptor (SERD). SAR439859 is a potent antagonist of ER (with an EC50 of 0.2 nM for ERα degradation). | |||
T2365 | Pilaralisib | SAR245408,XL-147 | PI3K |
Pilaralisib (XL-147) is an orally available small molecule that selectively inhibits the activity of phosphoinositide-3 kinase (PI3K). Pilaralisib has been used in trials studying the treatment of Cancer, Lymphoma, Solid... | |||
T7134 | Mavacamten | MYK-461,SAR439152 | Myosin |
Mavacamten (MYK-461) is an orally bioavailable inhibitor of cardiac myosin ATPase,( IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively) | |||
T7014 | Voxtalisib | XL765,SAR245409 | DNA-PK , PI3K , mTOR |
Voxtalisib (XL765) (SAR245409, XL765) is a dual inhibitor of mTOR/PI3K, mostly for p110γ with IC50 of 9 nM; also inhibits DNA-PK and mTOR. Phase 1/2. | |||
T23308 | SAR407899 hydrochloride | ROCK | |
ATP-competitive ROCK inhibitor | |||
T81968 | KY-1044 | SAR 445256,Alomfilimab | |
KY-1044 (Alomfilimab; SAR 445256) is a fully human IgG1 monoclonal antibody that targets the inducible costimulatory receptor (ICOS). This compound selectively depletes cells with high ICOS expression through antibody-de... | |||
TP2464 | Pentasarcosyl angiotensin II | (Sar)5 aii | |
Pentasarcosyl angiotensin II is a synthetic analog of angiotensin II. | |||
T3691 | (Rac)-SAR131675 | SAR131675 | VEGFR |
(Rac)-SAR131675 is an effective and specific VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity (IC50: 20 nmol/L) and VEGFR-3 autophosphorylation (IC50: 45 nmol/L) in HEK cells, respectively. SAR131675 is h... | |||
T3977L | Lifitegrast sodium | SAR-1118-023,SAR1118-023,SAR 1118-023,Xiidra | |
Lifitegrast sodium (SAR-1118) is an LFA-1 antagonist for the therapy of vascular complications of the eye. It inhibits T cell-mediated inflammation by blocking the binding of two cell surface proteins (lymphocyte functio... | |||
T9125 | Tolebrutinib | PRN2246,SAR442168 | BTK |
Tolebrutinib (PRN2246) is a potent, selective, orally active and brain-penetrant Bruton tyrosine kinase (BTK) inhibitor(IC50s of 0.4 and 0.7 nM in Ramos B cells and in HMC microglia cells, respectively). It exhibits effi... | |||
T77907 | Tusamitamab ravtansine | HuMAb2-3-SPDB-DM4,SAR-408701 | |
Tusamitamab ravtansine (SAR-408701) is a DM4-linked anti-CEACAM5 antibody-drug conjugate (ADC) comprising a humanized monoclonal antibody targeting carcinoembryonic antigen-related cell adhesion molecule-5 (CEACAM5) conj... | |||
T4473 | Ibiglustat | Venglustat,SAR402671,GZ402671 | Transferase |
Ibiglustat (GZ402671) is a potent and selective Glucosylceramide synthase inhibitor and ceramide glucosyltransferase inhibitor. Ibiglustat blocks the formation of glucosylceramide (GL-1), a key intermediate in the synthe... | |||
T2377 | Pilaralisib analogue | XL147 analogue,SAR245408 | Apoptosis , DNA-PK , PI3K |
Pilaralisib analogue (XL147 analogue) is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/γ. | |||
T12831 | SAR405 R enantiomer | Others | |
SAR405 R enantiomer is the less active enantiomer of SAR405. SAR405 is an inhibitor of PIK3C3/Vps34. | |||
T9702 | Eclitasertib | RIP kinase | |
Eclitasertib is a potent inhibitor of receptor-interacting protein kinase 1 (RIPK1, IC50 of <1 µΜ). |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T5S1959 | (-)-Asarinin | Fagarol,Sesamin,Pseudocubebin,Eleutheroside B4,Episesamin,Asarinin | Antibacterial |
(-)-Asarinin (Eleutheroside B4) shows antibacterial activity. | |||
T4120 | N-Methylsarcosine | N,N-Dimethylglycine,N,N-Dimethylaminoacetic acid,Dimethylglycine,DMG | Endogenous Metabolite |
N-Methylsarcosine (Dimethylglycine) is used as an athletic performance enhancer and immunostimulant. It is also used in the treatment of autism, epilepsy and mitochondrial disease. It is also employed as a biomarker of p... | |||
T3S2340 | Usaramine | (15E)-Retrorsine,Mucronatine,NISTC15503874 | Others , Antibacterial |
Usaramine (Mucronatine) demonstrates phytotoxicity against Lactuca sativa var. Carrascoy (lettuce) assessed as inhibition of seed germination at 50 ug/cm2 after 24 hr. | |||
T4S1962 | Beta-Asarone | Cis-Isoasarone,Cis-Asarone,Cis-Isoelemicin | NF-κB , JNK |
1. beta-Asarone (Cis-Isoelemicin) may be a potential preventive drug for Alzheimer's disease. 2. Beta-Asarone prevents autophagy and synaptic loss by reducing ROCK expression in SAMP8 mice. 3. The co-administration of be... | |||
T3765 | L-asarinin | (-)-Episesamin | Others |
L-asarinin ((-)-Episesamin) reduces peripheral blood concentration of IL-12 and inhibits the expression of CXCR3 and TLR4, which means Asarinin may have a role on the TLR4 pathway and produce prolongation of allograft he... | |||
T2733 | Sarsasapogenin | Parigenin,Sarsagenin | Apoptosis , NF-κB , Endogenous Metabolite |
Sarsasapogenin (Parigenin) is a steroidal sapogenin, that is the aglycosidic portion of a plant saponin. It is named after sarsaparilla (Smilax sp.), a family of climbing plants found in subtropical regions. It was one o... | |||
T3698 | Alpha-Asarone | α-Asarone,trans-Asarone | P450 , GABA Receptor , HMG-CoA Reductase |
alpha-Asarone (trans-Asarone) is a psychoactive compound with antidepressant-like activity in mice. | |||
T3887 | Rosarin | Others | |
Rosarin has anti-inflammatory and neuroprotective effects. Rosarin supresses the expression of the proinflammatory factors iNOS, IL-1 β, and TNF- α in the kidney and prefrontal cortex of brain in mice . | |||
T2826 | Asaraldehyde | Asarylaldehyde,2,4,5-trimethoxy-Benzaldehyde,Asaronaldehyde | COX |
Asaraldehyde (2,4,5-trimethoxy-Benzaldehyde), a natural COX-2 inhibitor, exhibits 17-fold selectivity than COX-1. | |||
TN2182 | Sarracenin | Others | |
Sarracenin is a natural product. Sarracenin shows cytotoxic activities against tumor cells. | |||
T6975 | Sarcosine | Sarcosinic acid,Methylaminoacetic acid,Sarcosin,Methylglycine,N-Methylaminoacetic acid,N-methylglycine | Others , GlyT , Endogenous Metabolite |
Sarcosine (Methylglycine) is a competitive inhibitor of the type I glycine transporter (GlyT1) and an N-methyl-D-aspartate receptor (NMDAR) co-agonist. | |||
TN7249 | Nor-rubrofusarin gentiobioside | ||
Nor-rubrofusarin gentiobioside is a natural product found in the leguminous plant Cassia vulgaris. | |||
TN1799 | Isorubrofusarin-6-O-β-gentiobioside | Isorubrofusarin 10-gentiobioside | BACE , AChR |
Isorubrofusarin-6-O-β-gentiobioside is derived from from Cassia obtusifolia Linn seeds and shows promising inhibitory activity against AChE and BACE1. | |||
TN2165 | Rubrofusarin gentiobioside | Rubrofusarin-6-O-beta-D-gentiobioside | ERK , NF-κB , TGF-beta/Smad |
Rubrofusarin gentiobioside (Rubrofusarin-6-O-beta-D-gentiobioside) can significantly decrease the expression of TGF-beta1 and fibronectin and NF-kappaB DNA binding activity, suggests that it has potential as a preventive... | |||
T20617 | Sarpagine | Raupin | |
Sarpagine is an alkaloid with the antihypertonic effect. | |||
TN3977 | Episesartemin A | Others | |
Episesartemin A is a natural product from Artemisia absinthium. | |||
TN4948 | Sargentol | Others | |
Sargentol is a natural product of Syringa, Oleaceae. The catalog number is TN4948 and the CAS number is 623928-18-7. Sargentol can be used as a reference standard. | |||
T81213 | Sarbronine M | ||
Scabronine M, a novel inhibitor, impedes NGF-induced neurite outgrowth from PC12 cells. | |||
T67969 | Confusarin | ||
Confusarin is a pheasin-like substance found in iris and bulbophyllum. | |||
TN6511 | Tessaric acid | ||
Tessaric acid has antifeedant and allelochemical effects. Tessaric acid derivatives induce G/M cell cycle arrest in human solid tumor cell lines. | |||
T81201 | Sartorypyrone B | ||
Sartorypyrone B, a 2β-acetoxyl analogue of chevalone C, is derived from the ethyl acetate extract of the culture of Neosartorya tsunodae (KUFC 9213), a fungus associated with marine sponges. This compound demonstrates po... | |||
TN4095 | Gamma-Diasarone | Others | |
gamma-Diasarone is a natural product for research related to life sciences. The catalog number is TN4095 and the CAS number is 80434-33-9. | |||
T24075 | Fusarochromanone | NSC-627608,FC101,NSC 627608,FC-101,FC 101 | |
Fusarochromanone is a melanoma growth inhibitor. | |||
TN6781 | SarMentine | ||
SarMentine is a natural product for research related to life sciences. The catalog number is TN6781 and the CAS number is 78910-33-5. | |||
T82220 | Hedysarimcoumestan B | ||
Hedysarumcoumestan B, a natural product, is isolated from the roots of Hedysarum multijugum [1]. | |||
T13266 | Usaramine N-oxide | Others | |
Usaramine N-oxide is a flavonoid isolated from Crotalaria pallida, and possesses anti-inflammatory activities. | |||
TN2055 | Periplogenin 3-[O-β-glucopyranosyl-(1→4)-β-sarmentopyranoside] | 4)-beta-sarmentopyranoside]'>Periplogenin 3-[O-beta-glucopyranosyl-(1->4)-beta-sarmentopyranoside] | Others |
Periplogenin 3-[O-beta-glucopyranosyl-(1->4)-beta-sarmentopyranoside] is a natural product from Periploca sepiumBge. | |||
T81211 | Sarmenoside III | ||
"Sarmenoside III, a hepatoprotective flavonol glycoside, has been isolated from the plant Sedum sarmentosum." | |||
T75495 | Rubrofusarin 6-O-β-D-glucopyranoside | ||
Rubrofusarin 6-O-β-D-glucopyranoside, a glycosidic derivative of Rubrofusarin, functions as an inhibitor of protein tyrosine phosphatase 1B (PTP1B) with an IC50 value of 87.36 μM. It is utilized in research investigating... | |||
T34533 | Sarisan | NSC27868,NSC-27868,NSC 27868 | |
Sarisan is a biochemical. | |||
TN2953 | 3-Hydroxysarpagine | Topoisomerase | |
3-Hydroxysarpagine is a natural product of Rauvolfia, Apocynaceae. The catalog number is TN2953 and the CAS number is 857297-90-6. 3-Hydroxysarpagine can be used as a reference standard. | |||
T81212 | Sarmenoside II | ||
Sarmenoside II, a flavonol glycoside, demonstrates inhibitory activity on lipid accumulation. It has been observed to reduce albumin-oleate-induced lipid accumulation in HepG2 cells by approximately 30% at a concentratio... | |||
TN5632 | Sarcandrone B | ||
Sarcandrone B is a natural product for research related to life sciences. The catalog number is TN5632 and the CAS number is 1190225-48-9. | |||
T82539 | DL-Asarinin | ||
DL-Asarinin (compound 88) is a natural product isolated from the waste leaves of Cinnamomum camphora [1]. | |||
T72581 | SARS-CoV MPro-IN-2 | ||
SARS-CoV MPro-IN-2 effectively inhibits the SARS-CoV-2 main protease (M pro), crucial for the virus's replication and transcription in host cells, with an IC50 value of 72.07 nM. Given its significant role in processing ... | |||
TN5002 | Sesartemin | Others | |
Sesartemin is a natural product of Rhaphidophora, Araceae. The catalog number is TN5002 and the CAS number is 77394-27-5. Sesartemin can be used as a reference standard. | |||
T72732 | Massarilactone H | ||
Massarilactone H, a polyketide, is a neuraminidase inhibitor, with an IC 50 of 8.18 µM . | |||
T34529 | Sarcostin | ||
Sarcostin is a pregnane ester glycoside isolated from the aerial parts of Stapelia variegata. | |||
TN4947 | Sarcandrone A | Others | |
Sarcandrone A is a natural product for research related to life sciences. The catalog number is TN4947 and the CAS number is 1190225-47-8. | |||
TN2181 | Sarmentosin | Others | |
Sarmentosin significantly lowers the SGPT level of patients suffering from chronic viral hepatitis, and shows a suppressive effect on cell-mediated immune responses in mice. It shows a good effect in lowering serum gluta... | |||
TN4946 | Sarcandrolide D | Others | |
Sarcandrolide D is a natural product for research related to life sciences. The catalog number is TN4946 and the CAS number is 1207185-03-2. | |||
T34525 | Sarcophine | Sarcophin,Sarcophin A | |
Sarcophine is a natural cembranoid from the Red Sea soft coral Sarcophyton glaucum. | |||
T81651 | Norrubrofusarin | Didemethylasperxanthone | |
Norrubrofusarin (Didemethylasperxanthone) is a natural compound derived through demethylation of Compound III, a metabolite of Aspergillus niger [1]. | |||
T36950 | Rubrofusarin triglucoside | ||
Rubrofusarin triglucoside, a glycoside isolated from Cassia obtusifolia Linn seeds, demonstrates inhibitory activity against human monoamine oxidase A (hMAO-A), exhibiting an IC50 value of 85.5 μM[1]. | |||
T79992 | Sarglaroids F | Caspase | |
Sarglaroids F (compound 6), an anti-inflammatory agent extracted from the roots of Grass Coral, suppresses LPS/ATP-induced IL-1β secretion by modulating K+ efflux and diminishing Caspase-1(P20) concentrations. Additional... | |||
TN4950 | Saropyrone | Others | |
Saropyrone is a natural product from Hypericum Japonicum. | |||
TN4952 | Sarracine N-oxide | Others | |
Sarracine N-oxide is a natural product of Senecio, Asteraceae. The catalog number is TN4952 and the CAS number is 19038-27-8. Sarracine N-oxide can be used as a reference standard. | |||
TN5928 | γ-Asarone | soasarone | |
γ-Asarone is a natural product for research related to life sciences. The catalog number is TN5928 and the CAS number is 5353-15-1. | |||
TN4949 | Sarmentocymarin | Others | |
Sarmentocymarin is a cardiac glucoside. | |||
T72867 | Fusarisetin A | ||
Fusarisetin A, a pentacyclic fungal metabolite, is an acinar morphogenesis inhibitor . | |||
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カタログ番号 | 製品名 | Species | Expression System |
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TMPY-02030 | CD82 Protein, Human, Recombinant (His) | Human | HEK293 |
CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetras... | |||
TMPY-05679 | SARS-CoV-2 Spike RBD Protein (hFc) | SARS-CoV-2 | HEK293 |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPK-00265 | SARS-COV-2 Nucleocapsid Protein (His & Avi), Biotinylated | SARS-CoV-2 | E. coli |
Nucleocapsid protein (N) is the major viral structural component; its main function is to protect and encapsidate the viral RNA forming viral RNP complex. It is encoded by the S segment vRNA and is abundantly expressed i... | |||
TMPK-01339 | 3CLpro/3C-like Protease Protein (S144A), SARS-COV-2, Recombinant | SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al... | |||
TMPK-01341 | 3CLpro/3C-like Protease Protein (P132H), SARS-COV-2, Recombinant | SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al... | |||
TMPK-01343 | 3CLpro/3C-like Protease Protein (A191T), SARS-COV-2, Recombinant | SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al... | |||
TMPY-05693 | SARS-CoV-2 Methyltransferase/ME Protein (His) | SARS-CoV-2 | E. coli |
Coronavirus encodes the 2’-O-MTase (2'O Methyltransferase) that is composed of the catalytic subunit nsp16 and the stimulatory subunit nsp10 and plays an important role in virus genome replication and evasion from innate... | |||
TMPJ-01449 | 3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant | SARS-CoV-2 | E. coli |
The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precur... | |||
TMPJ-01426 | SARS-CoV-2 NSP2 Protein (His) | SARS-CoV-2 | E. coli |
The positive-stranded RNA genome of the coronaviruses is translated from ORF1 to yield polyproteins that are proteolytically processed into intermediate and mature nonstructural proteins (nsps). SARS-CoV 2 polyproteins i... | |||
TMPK-00913 | SARS Spike S1 Protein (His & Avi), Biotinylated | SARS | HEK293 |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k... | |||
TMPJ-01448 | 3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant (His) | 2019-nCoV | E. coli |
The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precur... | |||
TMPH-03052 | EnoA Protein, Neosartorya fumigata, Recombinant (His) | Neosartorya fumigata | E. coli |
EnoA Protein, Neosartorya fumigata, Recombinant (His) is expressed in E. coli. | |||
TMPK-01416 | HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi), Biotinylated | Human | HEK293 |
HLA-B*15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B*15:01 we... | |||
TMPK-00439 | SARS-COV-2 Spike RBD Protein (His & Avi), Biotinylated | SARS-CoV-2 | HEK293 |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k... | |||
TMPK-00908 | SARS Spike S1 Protein (hFc & Avi) | SARS | HEK293 |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k... | |||
TMPK-00434 | SARS-COV-2 Spike RBD Protein (hFc & Avi), Biotinylated | SARS-CoV-2 | HEK293 |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k... | |||
TMPK-00264 | SARS-COV-2 Nucleocapsid Protein CTD Domain (His & Avi) | SARS-CoV-2 | E. coli |
Nucleocapsid protein (N) is the major viral structural component; its main function is to protect and encapsidate the viral RNA forming viral RNP complex. It is encoded by the S segment vRNA and is abundantly expressed i... | |||
TMPK-00433 | SARS-COV-2 Spike S1 Protein (hFc & Avi), Biotinylated | SARS-CoV-2 | HEK293 |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k... | |||
TMPK-00436 | SARS-COV-2 Spike S1 Protein (D614G, His & Avi) | SARS-CoV-2 | HEK293 |
The SARS-CoV-2 spike (S) protein is the target of vaccine design efforts to end the COVID-19 pandemic. Despite a low mutation rate, isolates with the D614G substitution in the S protein appeared early during the pandemic... | |||
TMPY-05699 | SARS-CoV Spike/S1 Protein (His), Biotinylated | SARS | Baculovirus-Insect Cells |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPY-05702 | SARS-CoV Spike/S1 Protein (mFc) | SARS | HEK293 |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPY-05707 | SARS-CoV-2 Spike RBD Protein (N354D, His) | SARS-CoV-2 | HEK293 |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPY-05714 | SARS-CoV-2 Spike RBD Protein (Avi & His), Biotinylated | SARS-CoV-2 | Baculovirus-Insect Cells |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPY-05009 | Asp f 1 Protein, Neosartorya fumigata, Recombinant (His) | Neosartorya fumigata | HEK293 |
Asp f 1 (Aspergillus fumigatus allergen 1) is a major allergen produced by the mycelia of Aspergillus fumigatus. It is not present in spores and can be used as a specific marker for the detection of germination of this f... | |||
TMPY-04894 | SARS-CoV (strain WH20) Plpro/papain-like protease (His) | SARS | E. coli |
The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. PLpro has the additional function of st... | |||
TMPY-05724 | SARS-CoV-2 Spike RBD Protein (G476S, His) | SARS-CoV-2 | HEK293 |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPY-05727 | SARS-CoV-2 3CLpro/3C-like protease Protein (His & Avi) | SARS-CoV-2 | E. coli |
3C-like protease (3CLpro) is the main protease of Humann Coronavirus. 3C-like protease (3CLpro) is a key enzyme, as it cleaves several sites to produce non-structural proteins that are essential for genome replication an... | |||
TMPY-05718 | SARS-CoV (Isolate Tor2) Spike S1+S2 ECD Protein (S577A, His) | SARS | Baculovirus-Insect Cells |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPY-05764 | SARS-CoV-2 Spike S1 NTD Protein (His & Avi), Biotinylated | SARS-CoV-2 | HEK293 |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPY-05956 | SARS-CoV-2 Spike S2 ECD Protein (aa 708-1207, His) | SARS-CoV-2 | HEK293 |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPY-04177 | SARS-CoV Spike/RBD Protein (rFc) | SARS | Baculovirus-Insect Cells |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPY-02870 | SARS-CoV Nucleocapsid Protein (His) | SARS | Baculovirus-Insect Cells |
Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both vi... | |||
TMPH-01740 | SARM1 Protein, Human, Recombinant (His & Myc) | Human | Baculovirus |
NAD(+) hydrolase, which plays a key role in axonal degeneration following injury by regulating NAD(+) metabolism. Acts as a negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway by promotin... | |||
TMPH-03051 | Asp f 4 Protein, Neosartorya fumigata, Recombinant (His & SUMO) | Neosartorya fumigata | E. coli |
Asp f 4 Protein, Neosartorya fumigata, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPH-03050 | Gel4 Protein, Neosartorya fumigata, Recombinant (His) | Neosartorya fumigata | Yeast |
Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in ... | |||
TMPH-00760 | Cutinase Protein, Fusarium solani subsp. Cucurbitae, Recombinant (His) | Neocosmosporum cucurbitae | Yeast |
Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle. Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of the fungal infe... | |||
TMPH-03492 | SARS-CoV-2 Non-structural protein 9/NSP9 Protein (Flag & hFc) | SARS-CoV-2 | HEK293 |
SARS-CoV-2 Non-structural protein 9/NSP9 Protein (Flag & hFc) is expressed in HEK293 with C-terminal hFC-Flag tag. The predicted molecular weight is 44.5 kDa. Accession number: P0DTD1 YP_009742616.1 | |||
TMPY-06078 | SARS-CoV-2 envelope(CoV-E) protein Protein (C40A & C43A & C44A, His & MBP) | SARS-CoV-2 | E. coli |
SARS-CoV-2 envelope(CoV-E) protein Protein (C40A & C43A & C44A, His & MBP) is expressed in E. coli. The predicted molecular weight is 52.2 kDa. Accession number: YP_009724392.1 | |||
TMPY-05820 | SARS-CoV-2 NSP3 Protein (His) | SARS-CoV-2 | E. coli |
SARS-CoV-2 NSP3 Protein (His) is expressed in E. coli. The predicted molecular weight is 19.87 kDa. Accession number: YP_009725299.1 | |||
TMPY-06555 | SARS-CoV-2 BQ.1.1 (Omicron) Spike S1+S2 trimer Protein (His) | SARS-CoV-2 | HEK293 |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPY-06485 | SARS-CoV-2 (BA.1.1) Spike S1+S2 trimer Protein (His) | SARS-CoV-2 | HEK293 |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPY-06560 | SARS-CoV-2 XBB (Omicron) Spike RBD Protein (His) | SARS-CoV-2 | HEK293 |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPY-06694 | SARS-CoV-2 CH.1.1 (Omicron) Spike S1+S2 trimer Protein (His) | SARS-CoV-2 | HEK293 |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPY-06305 | SARS-CoV-2 Spike S1 Protein (Q52 & A67V & 69-70 deletion & 144 deletion & E484K & D614G & Q677H, His) | SARS-CoV-2 | HEK293 |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPY-06244 | SARS-CoV-2 Spike RBD Protein (K417T & E484K & N501Y, hFc) | SARS-CoV-2 | HEK293 |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPY-06128 | SARS-CoV-2 Spike S1 Protein (Q677H, His) | SARS-CoV-2 | HEK293 |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPY-06220 | SARS-CoV-2 Nucleocapsid Protein (P199L & M234I, His) | SARS-CoV-2 | E. coli |
Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both vi... | |||
TMPY-06130 | SARS-CoV-2 Spike S1 Protein (W152C & L452R & D614G, His) | SARS-CoV-2 | HEK293 |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPY-06136 | SARS-CoV-2 Spike S1 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y, His) | SARS-CoV-2 | HEK293 |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPY-06144 | SARS-CoV-2 Nucleocapsid Protein (D377Y, His) | SARS-CoV-2 | E. coli |
Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both vi... | |||
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カタログ番号 | 製品名 | ||
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L7810 | High Solubility Polyfunctional Group Fragment Library | 1159 compounds | |
Highly soluble multifunctional fragment library contains 1159 kinds of fragment molecules. |