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Search Results for " sclerosis "

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124

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天然化合物

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
TP2315	Glatiramer Acetate		Others
	Glatiramer acetate (GA) is a synthetic amino acid copolymer that is approved for treatment of relapsing remitting multiple sclerosis (RRMS) and clinically isolated syndrome (CIS).		Others
T4283	SRI-011381		TGF-beta/Smad
	SRI-011381, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.		TGF-beta/Smad
T9125	Tolebrutinib	PRN2246,SAR442168	BTK
	Tolebrutinib (PRN2246) is a potent, selective, orally active and brain-penetrant Bruton tyrosine kinase (BTK) inhibitor(IC50s of 0.4 and 0.7 nM in Ramos B cells and in HMC microglia cells, respectively). It exhibits effi...		BTK
T9174	Icerguastat	Sephin 1,lcerguastat,IFB-088	Phosphatase
	Icerguastat (IFB-088) is a selective inhibitor of holophosphatase. Sephin1 safely and selectively inhibited a regulatory subunit of protein phosphatase 1 in vivo.		Phosphatase
T13408	ZK824190		Others , Serine Protease
	ZK824190 is an orally available and selective inhibitor of urokinase plasminogen activator (uPA) as a potential treatment for multiple sclerosis(IC50s of 237, 1600 and 1850 nM for uPA, tPA, and Plasmin, respectively).		Others , Serine Protease
T6403	Siponimod	BAF-312	S1P Receptor , LPL Receptor
	BAF312 (Siponimod (BAF-312)), a next-generation S1P receptor modulator, is specific for S1P1 and S1P5 receptors with EC50 of 0.39 nM and 0.98 nM, respectively. The specificity of BAF312 for S1P1 and S1P5 receptors exhibi...		S1P Receptor , LPL Receptor
T39924	NF-κΒ activator 2		NF-κB
	NF-κΒ Activator 2 is a potent, orally active compound that efficiently activates NF-κB with an EC50 value of 1.58 μM. By enhancing NF-κB expression and activation, it induces SOD 2 synthesis, rendering it useful for amyo...		NF-κB
T6923	Ozanimod	RPC-1063	S1P Receptor , LPL Receptor
	Ozanimod (RPC-1063) (RPC1063) is a specific oral S1P Receptor 1 modulator. Ozanimod has been used in trials studying the treatment of Crohn's Disease, Ulcerative Colitis, Multiple Sclerosis, and Relapsing Multiple Sclero...		S1P Receptor , LPL Receptor
T4031	S1p receptor agonist 1	S1p-receptor-agonist-1	S1P Receptor , LPL Receptor
	S1p receptor agonist 1 (S1p-receptor-agonist-1) is an S1P receptor agonist.		S1P Receptor , LPL Receptor
T16079	Mirodenafil	SK3530	PDE
	Mirodenafil is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.		PDE
T6561	Laquinimod	LAQ,ABR-215062	Apoptosis , Others , NF-κB
	Laquinimod (LAQ) is an effective immunomodulator, which is currently under development in phase III trials for the treatment of multiple sclerosis as an oral therapy.		Apoptosis , Others , NF-κB
T5129	SRI-011381 hydrochloride	SRI-011381 hydrochloride [1629138-41-5(free base)]	TGF-beta/Smad
	SRI-011381 hydrochloride, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.		TGF-beta/Smad
T2558	Cladribine	2-chlorodeoxyadenosine,2-Chloro-2′-deoxyadenosine,CldAdo,2CdA	Apoptosis , Adenosine deaminase
	Cladribine (2CdA), an adenosine deaminase inhibitor, is utilized in the treatment of lymphoproliferative diseases.		Apoptosis , Adenosine deaminase
TQ0126	Mirodenafil dihydrochloride	SK-3530 dihydrochloride	PDE
	Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.		PDE
T14219	Aminaftone	Aminaphthone	Endothelin Receptor
	Aminaftone, a derivative of 4-aminobenzoic acid, inhibits endothelin-1 (ET-1) production and can be used to study hypertension and systemic sclerosis.		Endothelin Receptor
T13553	Arimoclomol	BRX-220 free base	HSP
	Arimoclomol (BRX-220 free base) is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (ALS).		HSP
T3044	(E/Z)-Teriflunomide	Aubagio,HMR-1726,Flucyamide,A77 1726	Dehydrogenase
	(E/Z)-Teriflunomide (Aubagio), a orally-available Pyrimidine Synthesis Inhibitor, is used to treat relapsing multiple sclerosis.		Dehydrogenase
T67865	BJJF078		Glutaminase
	BJJF078, an aminopiperidine derivative, is a potent inhibitor of recombinant human and mouse glutamine aminotransferase (TG2) activity, with IC50 values of 41 and 54 nM for human and mouse glutamine aminotransferase, res...		Glutaminase
T31149	CYM5181	CYM 5181,CYM-5181
	CYM5181 is related to the body's immune system and can be used to study multiple sclerosis, transplant rejection, and adult respiratory distress syndrome.
T1066L	Ketanserin tartrate	KJK 945 tartrate,KJK-945 tartrate,KJK945 tartrate	5-HT Receptor , Serotonin Transporter , Adrenergic Receptor
	Ketanserin tartrate (KJK-945 tartrate) is a 5-HT2A receptor and α1-adrenergic receptor antagonist with antihypertensive activity, inhibits serotonin-induced vasoconstriction and platelet activation, and can be used in th...		5-HT Receptor , Serotonin Transporter , Adrenergic Receptor
T7534	Teriflunomide	A 77-1726	Others
	Teriflunomide (A 77-1726) is the principal active metabolite of leflunomide, an approved therapy for rheumatoid arthritis and multiple sclerosis.		Others
T77416	Opicinumab	BIIB033	Others
	Opicinumab (BIIB033) is a novel monoclonal antibody against LINGO-1 that may be used to prevent and delay acute optic neuritis and recurrent multiple sclerosis.		Others
T125901	14-Epiandrographolide
	14-Epiandrographolide is a compound derived from the above-ground parts of Andrographis paniculata that induces cell differentiation and can be used in the study of multiple sclerosis.
T0349	Riluzole	PK 26124,RP-54274	GABA Receptor , Sodium Channel , NMDAR
	Riluzole (RP-54274) is a glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.		GABA Receptor , Sodium Channel , NMDAR
T60120	SOD1-Derlin-1 inhibitor 56-59		Others
	SOD1-Derlin-1 inhibitor 56-59 is an inhibitor of SOD1-Derlin-1 interaction. SOD1-Derlin-1 inhibitor 56-59 is potential in Amyotrophic lateral sclerosis (ALS) research.		Others
T12177	Natalizumab		Integrin
	Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.		Integrin
T73689	Daclizumab	Ro 24-7375,Zenapax	IL Receptor
	Daclizumab (Zenapax) is a humanized monoclonal antibody that specifically inhibits the alpha subunit of IL-2R-HA. Daclizumab (Zenapax) can inhibit the binding of IL-2 and IL-2R-HA through specific binding to CD25. Dacliz...		IL Receptor
T62552	Ozanimod hydrochloride
	Ozanimod (RPC-1063) hydrochloride is a sphingosine 1-phosphate (S1P) receptor modulator that selectively binds S1P receptor subtype 1 (S1P1) and S1P5 (S1P5) with high affinity. Ozanimod hydrochloride can be used to study...
T60108	PDGFR Tyrosine Kinase Inhibitor III	PDGF Receptor Tyrosine Kinase Inhibitor III	PDGFR
	PDGFR Tyrosine Kinase Inhibitor III (PDGF Receptor Tyrosine Kinase Inhibitor III) (PDGF Receptor Tyrosine Kinase Inhibitor III) is a multikinase inhibitor that inhibits PDGFR, EGFR, FGFR, PKA, and PKC, respectively. PDGF...		PDGFR
T30087	Antroquinonol		Reactive Oxygen Species , Nrf2
	Antroquinonol is a ubiquinone derivative from Antrodia camphorata with anti-inflammatory and anticancer activities.Antroquinonol reduces oxidative stress and inhibits inflammation and sclerosis in mice with focal segment...		Reactive Oxygen Species , Nrf2
T0511	Tolperisone hydrochloride	Muscalm,Midocalm,Tolperisone HCl	Sodium Channel
	Tolperisone hydrochloride (Muscalm), a centrally acting muscle relaxant, is used in the therapy of pathologically increased tone of the cross-striated muscle resulted by neurological diseases (damage of the encephalomyel...		Sodium Channel
T21618L	Myelin Basic Protein (87-99) Acetate	Myelin Basic Protein (87-99) Acetate (118506-26-6 Free base)	Others
	Myelin Basic Protein (87-99) Acetate (Myelin Basic Protein (87-99) Acetate (118506-26-6 Free base)) is an encephalitogenic peptide that induces basic protein-specific T cell proliferation. Myelin Basic Protein (87-99) Ac...		Others
T1065	Baclofen	Lioresal	GABA Receptor
	Baclofen (Lioresal) is a synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing Baclofen acts as a gamma-aminobutyric acid (GABA) agonist sp...		GABA Receptor
T76713	Inebilizumab	MEDI 551,MT-0551,16C4-aFuc,VIB-0551	Others
	Inebilizumab is a humanized anti-CD19 monoclonal antibody with enhanced antibody-dependent cell-mediated cytotoxicity against B cells. Inebilizumab can be used to treat a range of autoimmune diseases associated with CD19...		Others
T3701	MCC950	CP-456773	NOD
			NOD
T60119	SOD1-Derlin-1 inhibitor-1	SOD1-Derlin-1 Inhibitor 56-20	Others
	SOD1-Derlin-1 inhibitor-1 (SOD1-Derlin-1 Inhibitor 56-20) (compound 56-20) is an inhibitor of SOD1-Derlin-1 interaction. SOD1-Derlin-1 inhibitor-1 inhibits SOD1 G93A -Derlin-1 complex with an IC 50 value of 7.11 μM. SOD1...		Others
T77484	Atibuclimab		TNF
	Atibuclimab is a chimeric monoclonal antibody targeting CD14, consisting of a mouse variable region and a human IgG4 Fc region. Atibuclimab can be used to treat amyotrophic lateral sclerosis. Atibuclimab reduces LPS-indu...		TNF
T11134	DZ2002		Others
	DZ2002, an orally active, reversible, and low-cytotoxic type III SAHH inhibitor (Ki=17.9 nM), exhibits significant immunosuppressive activity. It effectively prevents experimental dermal fibrosis by reversing the profibr...		Others
TQ0291	Firategrast	SB 683699	Integrin
	Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervous system (CNS) and decreases multiple sclerosis (MS) activity...		Integrin
T111959	IFB-088 acetate
	IFB-088 acetate, a benzyl guanidine derivative, is used to treat diseases and cancers associated with the PPP1R15A pathway and associated with protein misfolding stress, Examples include tau disease, synaptic riboprotein...
T3354	BIA 10-2474	BIA10-2474	FAAH , Autophagy
	BIA 10-2474 is a long-acting reversible inhibitor of fatty acid amide hydrolase (FAAH) that increases levels of the neurotransmitter anandamide in the central nervous system and in peripheral tissues (that is, the rest o...		FAAH , Autophagy
T14390L	(2R,3S)-Azelaprag		Apelin receptor
	(2R,3S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methylpyridin-3-yl)-4H-1,2,4-triazol-3-yl)-3-(5-methylpyrimidin-2-yl)butane-2-sulfonamide is an Apelin receptor agonist with an EC50 for Apelin receptors of 0.012 µM.(2R,3S)-N-(4-(...		Apelin receptor
T28778	Silperisone HCl	RGH5002,SILA336,RGH-5002,Silperisone hydrochloride,SILA-336
	Silperisone HCl (RGH-5002) blocks sodium and calcium channels in cells, decreases excitability and contractility of muscle cells, reduces peripheral tone, and acts as a muscle relaxant and peripheral vasodilator. Silperi...
T35689	MTP 131 acetate		Others
	MTP 131 is a mitochondria-targeted peptide antioxidant.1,2It localizes to the mitochondria and reducestert-butyl hydroperoxide-induced lipid peroxidation and apoptosis in SH-SY5Y cells when used at concentrations ranging...		Others
T30960	CL 232468	AEAD,CL-232468,CL232468
	CL 232468 may be used to treat multiple sclerosis.
T31978	GM-608	GM-606,GM-607,GM-604,GM-603,GM-605,GM-602
	GM-604(alirinetide) is a potential treatment for amyotrophic lateral sclerosis and ischemic stroke.
T29117	VSN-16	VSN-16R,VSN 16R,VSN16R
	VSN-16, a cannabinoid receptor agonist, is used potentially for the treatment of spasticity in multiple sclerosis.
T40116	IL-17A inhibitor 2
	IL-17A inhibitor 2 is an IL-17A inhibitor for treating psoriasis, rheumatoid arthritis, and multiple sclerosis.
T35135	WN1316	WN 1316,WN-1316
	WN1316 is a unique neuroprotectant against oxidative injury, being a highly promising remedy for the treatment of amyotrophic lateral sclerosis (ALS).
T69899	WOBE437
	WOBE437 is a selective endocannabinoid reuptake inhibitor which reduces disease progression in a mouse model of multiple sclerosis

Compounds

Target: TGF-beta/Smad

Tolebrutinib

T9125

Synonym: PRN2246,SAR442168

Target: BTK

Icerguastat

T9174

Synonym: Sephin 1,lcerguastat,IFB-088

Target: Others, Serine Protease

Siponimod

T6403

Synonym: BAF-312

Target: S1P Receptor, LPL Receptor

Target: S1P Receptor, LPL Receptor

S1p receptor agonist 1

T4031

Synonym: S1p-receptor-agonist-1

Target: S1P Receptor, LPL Receptor

Synonym: LAQ,ABR-215062

Target: Apoptosis, Others, NF-κB

SRI-011381 hydrochloride

T5129

Synonym: SRI-011381 hydrochloride [1629138-41-5(free base)]

Target: TGF-beta/Smad

Cladribine

T2558

Synonym: 2-chlorodeoxyadenosine,2-Chloro-2′-deoxyadenosine,CldAdo,2CdA

Target: Apoptosis, Adenosine deaminase

Mirodenafil dihydrochloride

TQ0126

Synonym: SK-3530 dihydrochloride

Target: PDE

Aminaftone

T14219

Synonym: Aminaphthone

Target: Endothelin Receptor

Arimoclomol

T13553

Synonym: BRX-220 free base

Target: HSP

(E/Z)-Teriflunomide

T3044

Synonym: Aubagio,HMR-1726,Flucyamide,A77 1726

Target: Dehydrogenase

Synonym: CYM 5181,CYM-5181

Target:

Ketanserin tartrate

T1066L

Synonym: KJK 945 tartrate,KJK-945 tartrate,KJK945 tartrate

Target: 5-HT Receptor, Serotonin Transporter, Adrenergic Receptor

14-Epiandrographolide

Synonym: PK 26124,RP-54274

Target: GABA Receptor, Sodium Channel, NMDAR

SOD1-Derlin-1 inhibitor 56-59

Synonym: Ro 24-7375,Zenapax

Target: IL Receptor

Ozanimod hydrochloride

T62552

Synonym:

Target:

PDGFR Tyrosine Kinase Inhibitor III

T60108

Synonym: PDGF Receptor Tyrosine Kinase Inhibitor III

Target: Reactive Oxygen Species, Nrf2

Tolperisone hydrochloride

T0511

Synonym: Muscalm,Midocalm,Tolperisone HCl

Target: Sodium Channel

Myelin Basic Protein (87-99) Acetate

T21618L

Synonym: Myelin Basic Protein (87-99) Acetate (118506-26-6 Free base)

Target: GABA Receptor

Inebilizumab

T76713

Synonym: MEDI 551,MT-0551,16C4-aFuc,VIB-0551

SOD1-Derlin-1 inhibitor-1

T60119

Synonym: SOD1-Derlin-1 Inhibitor 56-20

Target: FAAH, Autophagy

(2R,3S)-Azelaprag

T14390L

Synonym:

Target: Apelin receptor

Silperisone HCl

T28778

Synonym: RGH5002,SILA336,RGH-5002,Silperisone hydrochloride,SILA-336

Synonym: AEAD,CL-232468,CL232468

Target:

GM-608

T31978

Synonym: GM-606,GM-607,GM-604,GM-603,GM-605,GM-602

Target:

VSN-16

T29117

Synonym: VSN-16R,VSN 16R,VSN16R

Synonym: WN 1316,WN-1316

カタログ番号	製品名	別名	ターゲット
T4903	Heptadecanoic acid		Others , Endogenous Metabolite
	Heptadecanoic acid is a fatty acid of exogenous (primarily ruminant) origin. Many "odd" length long chain amino acids are derived from the consumption of dairy fats (milk and meat). Heptadecanoic acid constitutes 0.61% o...		Others , Endogenous Metabolite
T0492	Dimethyl fumarate	DMF	Reactive Oxygen Species , HIV Protease , Nrf2 , Endogenous Metabolite , Autophagy
	Dimethyl fumarate (DMF), a fumarate derivative, is used as antiinflammatory and immunomodulatory agent.
T22911	β-N-methylamino-L-alanine hydrochloride	L-BMAA hydrochloride	Others
	β-N-methylamino-L-alanine hydrochloride (L-BMAA hydrochloride) is a neurotoxin produced by cyanobacteria. L-BMAA hydrochloride could cause amyotrophic lateral sclerosis (ALS) and possibly other neurodegenerative diseases...		Others
T2532	Tauroursodeoxycholate	Taurolite,Tauroursodeoxycholic Acid,UR 906,Ursodeoxycholyltaurine,TUDCA	Apoptosis , ERK , P450 , Caspase , Endogenous Metabolite
	Tauroursodeoxycholate (UR 906), also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid that is produced in humans at a low concentration. Tauroursodeoxycholate is the more hydrophilic form of ursode...		Apoptosis , ERK , P450 , Caspase , Endogenous Metabolite
TN4263	Isoangustone A		MMP , GSK-3 , NF-κB , ROS , Akt , PI3K , CDK , JNK
	Isoangustone A has antitumor activity, it can induce G1 cycle arrest in DU145 human prostate and 4T1 murine mammary cancer cells, it inhibits cell proliferation by targeting PI3K, MKK4, and MKK7 in human melanoma. Isoang...		MMP , GSK-3 , NF-κB , ROS , Akt , PI3K , CDK , JNK
T75527	Chrexanthomycin C
	Chrexanthomycin C, an orally active marine-derived natural product, exhibits significant bioactivities and shows a binding affinity for DNA [(G4C2)4 G4] with a dissociation constant (Kd) of 2.8 mM. This compound holds po...
T38179	C16 3'-sulfo Galactosylceramide (d18:1/16:0)	C16 3'-sulfo Galactosylceramide (d18:1/16:0)	Others
	C16 3'-sulfo Galactosylceramide (d18:1/16:0) is a sulfated glycolipid.C16 3'-sulfo Galactosylceramide (d18:1/16:0) is a relatively abundant sulfide found in porcine brain and plasma that decreases throughout development ...		Others

天然物製品

Heptadecanoic acid

T4903

Synonym:

Target: Others, Endogenous Metabolite

Dimethyl fumarate

T0492

Synonym: DMF

Target: Reactive Oxygen Species, HIV Protease, Nrf2, Endogenous Metabolite, Autophagy

β-N-methylamino-L-alanine hydrochloride

T22911

Synonym: L-BMAA hydrochloride

Target: Others

Tauroursodeoxycholate

T2532

Synonym: Taurolite,Tauroursodeoxycholic Acid,UR 906,Ursodeoxycholyltaurine,TUDCA

Target: Apoptosis, ERK, P450, Caspase, Endogenous Metabolite

Isoangustone A

TN4263

Synonym:

Target: MMP, GSK-3, NF-κB, ROS, Akt, PI3K, CDK, JNK

C16 3'-sulfo Galactosylceramide (d18:1/16:0)

T38179

Synonym: C16 3'-sulfo Galactosylceramide (d18:1/16:0)

Target: Others

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-00831	IFN-beta Protein, Human, Recombinant (hFc)	Human	HEK293
	Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, paras...
TMPY-03145	IFN-beta Protein, Human, Recombinant	Human	CHO
	Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, paras...
TMPY-03467	IFN-beta Protein, Mouse, Recombinant	Mouse	HEK293
	Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, paras...
TMPY-05227	TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	Hepatitis A virus cellular receptor 2 (HAVCR2), formerly known as T cell immunoglobulin and mucin domain-3 (TIM-3), is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not ...
TMPY-01621	TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His)	Human	HEK293
	Hepatitis A virus cellular receptor 2 (HAVCR2), formerly known as T cell immunoglobulin and mucin domain-3 (TIM-3), is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not ...
TMPY-02970	CXCL10 Protein, Human, Recombinant	Human	E. coli
	(C-X-C motif) ligand (CXCL)10 (CXCL10) belongs to the ELR(-) CXC subfamily chemokine. CXCL10/IP-10 exerts its function through binding to chemokine (C-X-C motif) receptor 3 (CXCR3), a seven trans-membrane receptor couple...
TMPY-02956	Apolipoprotein L/APOL1 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	APOL1, also known as apolipoprotein L1, is a minor apoprotein component of HDL (High-density lipoprotein) or 'good cholesterol' which is synthesized in the liver and also in many other tissues, including pancreas, kidney...
TMPY-00635	IL-7R alpha/CD127 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Interleukin 7 Receptor alpha (IL-7RA), also known as CD127, is a 75 kDa hematopoietic receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7 receptor alp...
TMPY-01209	IL-7R alpha/CD127 Protein, Human, Recombinant (His)	Human	HEK293
	Interleukin 7 Receptor alpha (IL-7RA), also known as CD127, is a 75 kDa hematopoietic receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7 receptor alp...
TMPY-02568	IL-1 beta/IL-1F2 Protein, Canine, Recombinant	Canine	E. coli
	Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair ...
TMPY-02134	IL-1 beta/IL-1F2 Protein, Mouse, Recombinant	Mouse	E. coli
	Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair ...
TMPY-01999	IL-1 beta/IL-1F2 Protein, Human, Recombinant (His)	Human	E. coli
	Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair ...
TMPY-01049	IL-1 beta/IL-1F2 Protein, Human, Recombinant	Human	E. coli
	Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair ...
TMPY-02227	IL-1 beta/IL-1F2 Protein, Rat, Recombinant (mature form)	Rat	E. coli
	Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair ...
TMPY-02445	IL-1 beta/IL-1F2 Protein, Rhesus, Recombinant	Rhesus	E. coli
	Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair ...
TMPY-01355	Transglutaminase 2/TGM2 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Protein-glutamine gamma-glutamyltransferase 2, also known as Tissue transglutaminase, Transglutaminase C, Transglutaminase-2, and TGM2, is a member of the transglutaminase superfamily. TGM2 plays a role in cell growth an...
TMPY-02785	Tetranectin Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Tetranectin (TN), also known as C-type lectin domain family 3, member B (CLEC3B) is a member of the C-type lectin Family. It is plasminogen kringle 4 binding protein and regulates fibrinolysis and proteolytic processes v...
TMPY-05782	IL-18R alpha Protein, Mouse, Recombinant (mFc)	Mouse	HEK293
	Interleukin-18 receptor 1 (IL18R1) also known as CD218 antigen-like family member A, CDw218a, IL1 receptor-related protein, and CD218a, is an interleukin receptor of the immunoglobulin superfamily. IL18R1 is found expres...
TMPY-03951	IL-18R alpha Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293
	Interleukin-18 receptor 1 (IL18R1) also known as CD218 antigen-like family member A, CDw218a, IL1 receptor-related protein, and CD218a, is an interleukin receptor of the immunoglobulin superfamily. IL18R1 is found expres...
TMPY-01601	AXL Protein, Human, Recombinant (His)	Human	HEK293
	Axl receptor tyrosine kinase, together with Tyro3 and Mer, constitute the TAM family of receptor tyrosine kinases. In the nervous system, Axl and its ligand Growth-arrest-specific protein 6 (Gas6) are expressed on multip...
TMPY-01219	IL-18R alpha Protein, Human, Recombinant (His)	Human	HEK293
	Interleukin-18 receptor 1 (IL18R1) also known as CD218 antigen-like family member A, CDw218a, IL1 receptor-related protein, and CD218a, is an interleukin receptor of the immunoglobulin superfamily. IL18R1 is found expres...
TMPY-03198	IL-12B Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Subunit beta of interleukin 12 (also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40) (IL12B) is a subunit of human interleukin 12. IL12B/IL-12B is a cytokine that acts...
TMPY-01376	IL-18R alpha Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Interleukin-18 receptor 1 (IL18R1) also known as CD218 antigen-like family member A, CDw218a, IL1 receptor-related protein, and CD218a, is an interleukin receptor of the immunoglobulin superfamily. IL18R1 is found expres...
TMPY-02824	IL-18R alpha Protein, Rat, Recombinant (hFc)	Rat	HEK293
	Interleukin-18 receptor 1 (IL18R1) also known as CD218 antigen-like family member A, CDw218a, IL1 receptor-related protein, and CD218a, is an interleukin receptor of the immunoglobulin superfamily. IL18R1 is found expres...
TMPY-03516	IL-12B Protein, Mouse, Recombinant	Mouse	HEK293
	Subunit beta of interleukin 12 (also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40) (IL12B) is a subunit of human interleukin 12. IL12B/IL-12B is a cytokine that acts...
TMPY-01045	IL-12B Protein, Human, Recombinant (His)	Human	HEK293
	Subunit beta of interleukin 12 (also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40) (IL12B) is a subunit of human interleukin 12. IL12B/IL-12B is a cytokine that acts...
TMPY-05491	IL-18R alpha Protein, Human, Recombinant (hFc)	Human	HEK293
	Interleukin-18 receptor 1 (IL18R1) also known as CD218 antigen-like family member A, CDw218a, IL1 receptor-related protein, and CD218a, is an interleukin receptor of the immunoglobulin superfamily. IL18R1 is found expres...
TMPY-01585	SOD1 Protein, Human, Recombinant (His)	Human	E. coli
	SOD1 belongs to the Cu-Zn superoxide dismutase family. It binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmi...
TMPY-03653	CTRL Protein, Human, Recombinant (His)	Human	HEK293
	CTRL-1, also known as chymotrypsin-like protease, belongs to thepeptidase S1 family. CTRL-1 contains 1peptidase S1 domain. Its expression is increased in preeclampsia (PE). Placental-derived chymotrypsin-like protease is...
TMPY-02196	VAPB Protein, Human, Recombinant (His)	Human	E. coli
	Vesicle-associated membrane protein-associated protein B / C, also known as VAMP-B/VAMP-C, VAMP-associated protein B/C, VAP-B/VAP-C and VAPB, is a single-pass type IV membrane protein that belongs to the VAMP-associated ...
TMPK-00279	RGMA Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Repulsive guidance molecule (RGM) is a glycosylphosphatidylinositol (GPI)-anchored glycoprotein that has diverse functions in the developing and pathological central nervous system (CNS). The binding of RGM to its recept...
TMPK-00278	RGMA Protein, Human, Recombinant (His & Avi)	Human	HEK293
	Repulsive guidance molecule (RGM) is a glycosylphosphatidylinositol (GPI)-anchored glycoprotein that has diverse functions in the developing and pathological central nervous system (CNS). The binding of RGM to its recept...
TMPJ-00763	ANG Protein, Human, Recombinant	Human	E. coli
	Angiogenin belongs to the pancreatic ribonuclease family. Angiogenin is primarily expressed in the liver. It may act as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular t...
TMPJ-00623	BAFF/TNFSF13B Protein, Rhesus macaque, Recombinant (hFc)	Rhesus Macaque	Human Cells
	TNFSF13B is also known as B-cell activating factor (BAFF), BLyS and TNLG7A, is a member of TNF ligand superfamily. TNFSF/TNFRSF members function as key molecules in local and systemic inflammatory network, and the plasma...
TMPY-03811	KCT2 Protein, Human, Recombinant (His)	Human	HEK293
	C5orf15 (Chromosome 5 Open Reading Frame 15, also known as KCT2) is a Protein Coding gene. KCT2 gene maps to human chromosome 5q31.1 and is conserved in human, chimpanzee, cow, rat, and chicken. KCT2 is a 265 amino acid ...
TMPY-03828	IFN-beta Protein, Rhesus, Recombinant (mFc)	Rhesus	HEK293
	Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, paras...
TMPY-02456	IFN-beta Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, paras...
TMPY-03501	Optineurin Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	OPTN (Optineurin) is a Protein Coding gene. The Optineurin gene encodes the coiled-coil containing protein optineurin. Optineurin is a multifunctional adaptor protein intimately involved in various vesicular trafficking ...
TMPY-02748	LRP-10 Protein, Human, Recombinant (His)	Human	HEK293
	LRP10 (low-density lipoprotein Receptor Related Protein 10) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes a low-density lipoprotein receptor family protein. A simi...
TMPY-02653	LRP-10 Protein, Human, Recombinant (hFc)	Human	HEK293
	LRP10 (low-density lipoprotein Receptor Related Protein 10) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes a low-density lipoprotein receptor family protein. A simi...
TMPJ-00351	IL-23R Protein, Human, Recombinant (aa 24-353, hFc)	Human	Human Cells
	Interleukin 23 receptor (IL23R) is a type I cytokine receptor for IL23. IL23 receptor complex is comprised of two subunits, the IL12Rβ1 subunit, which is shared with several cytokines, and a subunit that is unique to IL-...
TMPY-05463	TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (mFc)	Human	HEK293
	Hepatitis A virus cellular receptor 2 (HAVCR2), formerly known as T cell immunoglobulin and mucin domain-3 (TIM-3), is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not ...
TMPY-03677	TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Hepatitis A virus cellular receptor 2 (HAVCR2), formerly known as T cell immunoglobulin and mucin domain-3 (TIM-3), is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not ...
TMPY-00553	TIM-3/KIM-3/HAVCR2 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293
	Hepatitis A virus cellular receptor 2 (HAVCR2), formerly known as T cell immunoglobulin and mucin domain-3 (TIM-3), is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not ...
TMPY-03424	TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Hepatitis A virus cellular receptor 2 (HAVCR2), formerly known as T cell immunoglobulin and mucin domain-3 (TIM-3), is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not ...
TMPY-06296	TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293
	Hepatitis A virus cellular receptor 2 (HAVCR2), formerly known as T cell immunoglobulin and mucin domain-3 (TIM-3), is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not ...
TMPY-05428	TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (hFc)	Human	HEK293
	Hepatitis A virus cellular receptor 2 (HAVCR2), formerly known as T cell immunoglobulin and mucin domain-3 (TIM-3), is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not ...
TMPJ-01219	IL-23R Protein, Mouse, Recombinant (hFc)	Mouse	Human Cells
	Interleukin 23 receptor (IL23R), a heterodimer of the IL12 receptor β1 (IL12Rβ1) and IL12Rβ2, is a type I cytokine receptor for IL23. IL23R is comprised of two subunits, the IL12Rβ1 subunit, which is shared with several ...
TMPY-02952	SIAE Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Sialate O-acetylesterase belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. It is widely expressed with high expression in the testis, prostate, and colon. The systematic name of th...
TMPY-04943	CXCL10 Protein, Rat, Recombinant (His)	Rat	Yeast
	(C-X-C motif) ligand (CXCL)10 (CXCL10) belongs to the ELR(-) CXC subfamily chemokine. CXCL10/IP-10 exerts its function through binding to chemokine (C-X-C motif) receptor 3 (CXCR3), a seven trans-membrane receptor couple...
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IFN-beta Protein, Human, Recombinant (hFc)

TMPY-00831

Species: Human

Expression System: HEK293

IFN-beta Protein, Human, Recombinant

TMPY-03145

Species: Human

Expression System: CHO

IFN-beta Protein, Mouse, Recombinant

TMPY-03467

Species: Mouse

Expression System: HEK293

TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His), Biotinylated

TMPY-05227

Species: Human

Expression System: HEK293

TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His)

TMPY-01621

Species: Human

Expression System: HEK293

CXCL10 Protein, Human, Recombinant

TMPY-02970

Species: Human

Expression System: E. coli

Apolipoprotein L/APOL1 Protein, Human, Recombinant (His)

TMPY-02956

Species: Human

Expression System: Baculovirus-Insect Cells

IL-7R alpha/CD127 Protein, Cynomolgus, Recombinant (His)

TMPY-00635

Species: Cynomolgus

Expression System: HEK293

IL-7R alpha/CD127 Protein, Human, Recombinant (His)

TMPY-01209

Species: Human

Expression System: HEK293

IL-1 beta/IL-1F2 Protein, Canine, Recombinant

TMPY-02568

Species: Canine

Expression System: E. coli

IL-1 beta/IL-1F2 Protein, Mouse, Recombinant

TMPY-02134

Species: Mouse

Expression System: E. coli

IL-1 beta/IL-1F2 Protein, Human, Recombinant (His)

TMPY-01999

Species: Human

Expression System: E. coli

IL-1 beta/IL-1F2 Protein, Human, Recombinant

TMPY-01049

Species: Human

Expression System: E. coli

IL-1 beta/IL-1F2 Protein, Rat, Recombinant (mature form)

TMPY-02227

Species: Rat

Expression System: E. coli

IL-1 beta/IL-1F2 Protein, Rhesus, Recombinant

TMPY-02445

Species: Rhesus

Expression System: E. coli

Transglutaminase 2/TGM2 Protein, Human, Recombinant (His)

TMPY-01355

Species: Human

Expression System: Baculovirus-Insect Cells

Tetranectin Protein, Mouse, Recombinant (His)

TMPY-02785

Species: Mouse

Expression System: HEK293

IL-18R alpha Protein, Mouse, Recombinant (mFc)

TMPY-05782

Species: Mouse

Expression System: HEK293

IL-18R alpha Protein, Cynomolgus, Recombinant (hFc)

TMPY-03951

Species: Cynomolgus

Expression System: HEK293

AXL Protein, Human, Recombinant (His)

TMPY-01601

Species: Human

Expression System: HEK293

IL-18R alpha Protein, Human, Recombinant (His)

TMPY-01219

Species: Human

Expression System: HEK293

IL-12B Protein, Mouse, Recombinant (His)

TMPY-03198

Species: Mouse

Expression System: HEK293

IL-18R alpha Protein, Mouse, Recombinant (His)

TMPY-01376

Species: Mouse

Expression System: HEK293

IL-18R alpha Protein, Rat, Recombinant (hFc)

TMPY-02824

Species: Rat

Expression System: HEK293

IL-12B Protein, Mouse, Recombinant

TMPY-03516

Species: Mouse

Expression System: HEK293

IL-12B Protein, Human, Recombinant (His)

TMPY-01045

Species: Human

Expression System: HEK293

IL-18R alpha Protein, Human, Recombinant (hFc)

TMPY-05491

Species: Human

Expression System: HEK293

SOD1 Protein, Human, Recombinant (His)

TMPY-01585

Species: Human

Expression System: E. coli

CTRL Protein, Human, Recombinant (His)

TMPY-03653

Species: Human

Expression System: HEK293

VAPB Protein, Human, Recombinant (His)

TMPY-02196

Species: Human

Expression System: E. coli

RGMA Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00279

Species: Human

Expression System: HEK293

RGMA Protein, Human, Recombinant (His & Avi)

TMPK-00278

Species: Human

Expression System: HEK293

ANG Protein, Human, Recombinant

TMPJ-00763

Species: Human

Expression System: E. coli

BAFF/TNFSF13B Protein, Rhesus macaque, Recombinant (hFc)

TMPJ-00623

Species: Rhesus Macaque

Expression System: Human Cells

KCT2 Protein, Human, Recombinant (His)

TMPY-03811

Species: Human

Expression System: HEK293

IFN-beta Protein, Rhesus, Recombinant (mFc)

TMPY-03828

Species: Rhesus

Expression System: HEK293

IFN-beta Protein, Mouse, Recombinant (hFc)

TMPY-02456

Species: Mouse

Expression System: HEK293

Optineurin Protein, Human, Recombinant (His & GST)

TMPY-03501

Species: Human

Expression System: Baculovirus-Insect Cells

LRP-10 Protein, Human, Recombinant (His)

TMPY-02748

Species: Human

Expression System: HEK293

LRP-10 Protein, Human, Recombinant (hFc)

TMPY-02653

Species: Human

Expression System: HEK293

IL-23R Protein, Human, Recombinant (aa 24-353, hFc)

TMPJ-00351

Species: Human

Expression System: Human Cells

TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (mFc)

TMPY-05463

Species: Human

Expression System: HEK293

TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (hFc)

TMPY-03677

Species: Mouse

Expression System: HEK293

TIM-3/KIM-3/HAVCR2 Protein, Cynomolgus, Recombinant (hFc)

TMPY-00553

Species: Cynomolgus

Expression System: HEK293

TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (His)

TMPY-03424

Species: Mouse

Expression System: HEK293

TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (hFc & Avi), Biotinylated

TMPY-06296

Species: Human

Expression System: HEK293

TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (hFc)

TMPY-05428

Species: Human

Expression System: HEK293

IL-23R Protein, Mouse, Recombinant (hFc)

TMPJ-01219

Species: Mouse

Expression System: Human Cells

SIAE Protein, Human, Recombinant (His)

TMPY-02952

Species: Human

Expression System: Baculovirus-Insect Cells

CXCL10 Protein, Rat, Recombinant (His)

TMPY-04943

Species: Rat

Expression System: Yeast

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カタログ番号	製品名
L2620	Anti-Neurodegenerative Disease Compound Library	2154 compounds
	A unique collection of 2154 compounds related to neurodegenerative diseases can be used for HTS or HCS；
L8710	Cuproptosis Compound Library	400 compounds
	TargetMol’s Cuproptosis Compound Library is a collection of 400 compounds related to copper-dependent death that can be used to study its mechanism and related diseases.
L7600	Chemokine Inhibitor Library	59 compounds
	A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening;

ライブラリー

Anti-Neurodegenerative Disease Compound Library

L2620

Compounds: 2154

Cuproptosis Compound Library

L8710

Compounds: 400

Chemokine Inhibitor Library

L7600

Compounds: 59