|
T21371 |
Apraclonidine hydrochloride
|
Iopidine,ALO 2145,Apraclonidina,P-aminoclonidine,4-Aminoclonidine,Apraclonidine HCl,Apraclonidinum |
Adrenergic Receptor
|
|
Apraclonidine hydrochloride (ALO 2145) is an α2-adrenergic agonist and a weak α-1 adrenergic receptor agonist. Apraclonidine hydrochloride lowers intraocular pressure in human eyes and can be used in studies about glauco... |
|
T0378 |
Oxybuprocaine hydrochloride
|
Risedronic Acid,Oxybuprocaine HCl |
Sodium Channel
|
|
Oxybuprocaine hydrochloride (Oxybuprocaine HCl), a local anesthetic, is used especially in otolaryngology and ophthalmology. |
|
T19004 |
Hoechst 33258 analog 2
|
|
Others
|
|
Hoechst 33258 analog 2 is part of a family of blue fluorescent dyes used to stain DNA. |
|
T0141L |
Cefalonium Dihydrate(5575-21-3 free base)
|
Cefalonium Dihydrate |
Others
|
|
Cefalonium Dihydrate(5575-21-3 free base) is a first-generation cephalosporin antibiotic. |
|
T1483 |
Citalopram hydrobromide
|
Lu 10-171,Nitalapram HBr,Bonitrile HBr,XU-62-320,Lu 10-171 HBr,Citalopram HBr |
5-HT Receptor
,
Serotonin Transporter
,
Autophagy
|
|
Citalopram hydrobromide (XU-62-320) , a selective serotonin reuptake inhibitor (SSRI), selectively inhibits the CNS neuronal reuptake of serotonin, thereby potentiating serotonergic activity in the central nervous system... |
|
T2525 |
Alosetron hydrochloride
|
Lotronex,GR 68755C,GR 68755,GR 68755X |
5-HT Receptor
|
|
Alosetron hydrochloride (GR 68755) is the hydrochloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist. Alosetron blocks the actions of serotonin at 5-HT3 sites in the peripheral nervous system,... |
|
T7142 |
Cephalosporin C zinc salt
|
|
Others
|
|
Cephalosporin C zinc salt was a potent inhibitor of SAMHD1 (IC50 : 1.1 ± 0.1 µM), and this inhibition was largely attributable to the presence of zinc. |
|
T6958 |
Prucalopride Succinate
|
R-108512,Resolor Succinate |
5-HT Receptor
|
|
Prucalopride Succinate (Resolor Succinate) is a selective, high affinity 5-HT4 receptor agonist, inhibiting human 5-HT(4a) and 5-HT(4b) receptor with Ki value of 2.5 nM and 8 nM, respectively. |
|
T2706 |
Palomid 529
|
P529,SG 00529 |
Apoptosis
,
mTOR
|
|
Palomid 529 (SG 00529) has been used in trials studying the treatment of Age-Related Macular Degeneration. |
|
T14495 |
Baloxavir
|
Baloxavir acid,S-033447 |
Influenza Virus
|
|
Baloxavir (S-033447) is a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit. |
|
T0660 |
Beta-Tetralone
|
2-Tetralone |
P450
|
|
Beta-Tetralone (2-Tetralone) is a ketone derivative of tetralin. |
|
T0102 |
Naloxone hydrochloride
|
Naloxone HCl |
Opioid Receptor
|
|
Naloxone hydrochloride (Naloxone HCl) is a specific opiate antagonist that has no agonist activity. It is a competitive antagonist at mu, delta, and kappa opioid receptors. |
|
T8785 |
HALOFUGINONE LACTATE
|
|
DNA/RNA Synthesis
,
TGF-beta/Smad
|
|
HALOFUGINONE LACTATE is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D. febrifuga.Halofuginone inhibits prolyl-tRNA synthetase in an ATP-dependent manner ... |
|
T67851 |
Rac Desmethyl Citalopram Hydrochloride
|
|
5-HT Receptor
|
|
rac Desmethyl Citalopram Hydrochloride is a 5-hydroxy tryptamine uptake inhibitor with IC50 value of 0.013 μM. |
|
T22936 |
Idalopirdine Hydrochloride
|
Lu AE58054 Hydrochloride,Idalopirdine HCl |
5-HT Receptor
|
|
Idalopirdine Hydrochloride (Lu AE58054 Hydrochloride) is an in-vivo binding affinity and effect, in-vitro selectivity and potency of 5-HT(6)R antagonist (Ki: 0.83 nM). |
|
T40437L |
Caloxin 2A1 acetate
|
|
Proton pump
|
|
Caloxin 2A1 acetate is an inhibitor of extracellular plasma membrane Ca2+-ATPase (PMCA) peptide. Caloxin 2A1 acetate inhibits Ca2+-dependent formation of the 140-kDa acid-stable acylphosphate. |
|
T1122 |
Cephalothin sodium
|
Cefalotin sodium,Cephalothin,Cefalotin |
Antibacterial
,
Antibiotic
|
|
Cephalothin sodium (Cefalotin) binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Cephalothin sodium (Cefalotin) is the sodium salt form of cephalothin, a... |
|
T30586L |
Brefonalol HCl
|
Brefonalol HCl(103880-26-8 Free base) |
Adrenergic Receptor
|
|
Brefonalol HCl is an ADRA antagonist used in the treatment of neurological disorders and cardiovascular diseases and can be used in the study of angina pectoris, arrhythmias and hypertension. |
|
T27399 |
Galocitabine
|
RO 091390,RO-091390,RO091390,RO-09-1390,Neofrutulon |
Others
|
|
Galocitabine (Neofrutulon), a thymidylate synthase inhibitor, is used potentially for the treatment of cancer. |
|
T19914 |
Chlorothalonil
|
DAC 2787,Daconil,Daconil M |
Antifungal
|
|
Chlorothalonil (DAC 2787) is a broad-spectrum fungicide with high efficiency and low toxicity. Chlorothalonil is widely used to control various pests such as fruit trees and vegetable leaves. Chlorothalonil also has good... |
|
T15461 |
Halopemide
|
|
Others
,
Phospholipase
,
Dopamine Receptor
|
|
Halopemide is a potent inhibitor of PLD (IC50 = 220 and 310 nM for human PLD1 and PLD2). Halopemid is an antagonist of dopamine receptors. Halopemid can be used in psychotropic research. |
|
T12444 |
Phentolamine Analogue 1
|
|
Adrenergic Receptor
|
|
Phentolamine Analogue 1 is an analogue of phentolamine. Phentolamine is a nonselective antagonist of α-adrenergic. |
|
T11070 |
DO34 analog
|
|
Others
|
|
DO34 analog is a triazole DAGL(α) inhibitor. |
|
T0141 |
Cephalonium
|
Cefalonium |
Others
|
|
Cephalonium (Cefalonium) is a first-generation cephalosporin antibiotic. |
|
T4993 |
Afloqualone
|
HQ-495 |
GABA Receptor
|
|
Afloqualone (HQ-495) is a agonist of GABA Receptor . Target: GABA Receptor in vitro: Afloqualone is a quinazolinone family GABAergic drug. It has sedative and muscle-relaxant effects, resulting from its agonist activity ... |
|
T12770 |
RR-11a analog
|
aza-peptide Michael acceptor, 7a |
Parasite
|
|
RR-11a analog (aza-peptide Michael acceptor, 7a) is an inhibitor of asparaginyl endopeptidase with IC50s of 4.5 nM, 4.5 nM and 31 nM for AE1 in Trichomonas Vaginalis, AE in Ixodes ricinus and AE in Schistosoma mansoni, r... |
|
T0116 |
Balofloxacin
|
|
DNA gyrase
,
Antibacterial
,
Antibiotic
|
|
Balofloxacin, a quinolone antibiotic, can inhibit the synthesis of bacterial DNA by interfering with the DNA gyrase. |
|
T4384 |
Halofenozide
|
|
Others
|
|
Halofenozide is an ecdysteroid agonist and used as a pesticide. |
|
T25487 |
Haloperidol decanoate
|
KD 16,KD-136,KD 136,Neoperidole,Haldol |
Others
|
|
Haloperidol decanoate (KD 16) is a typical antipsychotic agent utilized as maintenance treatment for schizophrenia and mood disorders formulated as an ester for intramuscular injection. |
|
T32043 |
HaloPROTAC3
|
Halo PROTAC-3,HaloPROTAC 3,HaloPROTAC-3 |
Ligand for E3 Ligase
|
|
HaloPROTAC3 (HaloPROTAC-3) is a conjugate of ligands for E3 and 16-atom-length linker and a degrader of HaloTag fusion proteins. |
|
T0954 |
Halothane
|
Narcotane,Anestan |
Potassium Channel
,
Chloride channel
,
GABA Receptor
,
NMDAR
|
|
Halothane (Anestan) is a nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. NITROUS OXIDE is often given concomitantly.... |
|
T7666 |
Valorphin TFA(144313-54-2(free base))
|
Valorphin TFA(144313-54-2(free bas)) |
Others
|
|
Valorphin TFA(144313-54-2(free base)) is a semisynthetic derivative of dihydrovaltrate with opioid analgesic activity |
|
T9436 |
BenzeneazoMalononitrile
|
|
Others
|
|
BenzeneazoMalononitrile inhibits the growth of many types of cells, including therapeutic cells. It has also been shown to inhibit the activity of several enzymes, including those involved in drug metabolism. It has also... |
|
T126461 |
Aloenin B
|
|
|
|
Aloenin B, a compound isolated from the leaves and roots of Aloe vera, has neuroprotective activity against glutamate-induced neuronal death in HT22 cells. |
|
T76704 |
Tralokinumab
|
CAT-354,LP 0162 |
IL Receptor
|
|
Tralokinumab is a fully human IgG4 monoclonal antibody with a high affinity for IL-13 alone. Tralokinumab's potential anti-inflammatory activity prevents IL-13 receptor interaction and subsequent downstream signaling and... |
|
T6576 |
Malotilate
|
Malotilatum,NKK 105,Kantec |
Lipoxygenase
|
|
Malotilate (Kantec) is a medicine used for the therapy of liver cirrhosis. |
|
T2542 |
Prucalopride
|
R-93877 |
5-HT Receptor
|
|
Prucalopride (R-93877) is a selective, high-affinity 5-HT4A/4B receptor agonist (Ki: 2.5/8 nM). It has >290-fold selectivity for 5-HT4A/4B receptor than other 5-HT receptor subtypes. |
|
T10858 |
COH34 analog 1
|
|
Others
|
|
COH34 analog 1 is a COH34 oxidation analogue that can be used to synthesize active compounds. |
|
T2377 |
Pilaralisib analogue
|
XL147 analogue,SAR245408 |
Apoptosis
,
DNA-PK
,
PI3K
|
|
Pilaralisib analogue (XL147 analogue) is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/γ. |
|
T22328 |
Ethyl potassium malonate
|
Potassium 3-ethoxy-3-oxopropanoate,Malonic Acid Monoethyl Ester Potassium Salt |
Others
|
|
Ethyl potassium malonate, a competitive inhibitor of the enzyme succinate dehydrogenase, acts as a precursor to produce (trimethylsilyl)ethyl malonate, which is utilized to prepare beta-ketoesters by acylation and serves... |
|
T2058 |
Palosuran
|
ACT-058362 |
GPR
|
|
Palosuran (ACT-058362) (ACT-058362) is a new potent and specific antagonist of the human UT receptor. |
|
T20828 |
Citalopram
|
Cipram,Lu 10-171,Lu-10-171 Lu10-171 |
5-HT Receptor
|
|
Citalopram (Lu 10-171 is an orally active, selective serotonin reuptake inhibitor (SSRI), a selective 5-hydroxytryptamine reuptake inhibitor, and a racemic mixture of the S(+)-enantiomer (Escitalopram) and the R(-)-enant... |
|
T69984 |
Ticalopride
|
|
5-HT Receptor
|
|
Ticalopride is a 5-HT3 receptor agonist used in the treatment of digestive disorders, orofacial disorders, otorhinolaryngologic disorders, and may be used in the study of bulimia nervosa, gastroesophageal reflux, and irr... |
|
T5122 |
Alofanib
|
RPT835 |
Apoptosis
,
FGFR
|
|
Alofanib (RPT835) is a selective allosteric inhibitor of FGFR2 and has a dramatic inhibitory effect on FGF2-induced phosphorylation of FRS2a in KATO III cells (IC50 <10 nM). It has no direct effect on FGF2-dependent FGFR... |
|
T7105 |
Zinc phthalocyanine
|
ZnPc |
Others
|
|
Zinc phthalocyanine (ZnPc) are photosensitive,is commonly applied in industry (catalysts, photoconductors) and biomedical (photodynamic therapy). |
|
T2518 |
ARRY-380 (analog )
|
HER2-Inhibitor-1,ARRY380,ARRY-380 analog |
EGFR
,
HER
|
|
ARRY-380 analog (HER2-Inhibitor-1) is a potent and selective HER2 inhibitor. |
|
T30027 |
Amosulalol
|
|
Adrenergic Receptor
|
|
Amosulalol is a combined alpha and beta adrenoceptor antagonist. |
|
T19999 |
1-Tetralol, (S)-
|
(S)-Tetralin-1-ol,(S)-(+)-1,2,3,4-Tetrahydro-1-naphthol,(S)-1-Hydroxytetralin,J330.337C |
Others
|
|
1-Tetralol, (S)- ((S)-1-Hydroxytetralin) can be used as a substrate of AKR1C1 in cell assays. |
|
T16022 |
Arhalofenate
|
JNJ 39659100,MBX 102 |
PPAR
|
|
Arhalofenate (JNJ 39659100) is a selective partial agonist of peroxisome proliferator-activated receptor PPARγ. It is used for the treatment of type 2 diabetes. |
|
T20570 |
Labetalol
|
Apo-Labetalol,Albetol,Trandate,Dilevalol,Normodyne |
Adrenergic Receptor
|
|
Labetalol (Apo-Labetalol) is a mixed alpha/beta-adrenergic antagonist.It is used to treat high blood pressure. It can be given by mouth for long term hypertension management or intravenously in severe hypertensive situat... |
