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Search Results for " IL-4 "

ターゲット

阻害剤

天然化合物

211

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T36526	IL-17 modulator 4		Interleukin
	IL-17 modulator 4 is a prodrug of IL-17 modulator 1 which is an efficacious modulator of IL-17.		Interleukin
T36527	IL-4-inhibitor-1		IL Receptor
	IL-4 inhibitor is an inhibitor of IL-4.1It binds to IL-4 with a Kdvalue of 1.8 μM and inhibits IL-4 activity in a cell-based reporter assay (EC50= 1.81 μM). It is selective for IL-4 over IL-13 (EC50= 18.2 μM). IL-4 inhib...		IL Receptor
T40107	IL-17 modulator 4 sulfate
	IL-17 modulator 4 sulfate is a prodrug of IL-17 modulator 1 . IL-17 modulator 1 is an orally active, highly efficacious IL-17 modulator.
T9926	Omalizumab		Others
	Omalizumab is a recombinant humanized monoclonal antibody against human immunoglobulin E IgE)		Others
T9631	IRAK-4 protein kinase inhibitor 2		IRAK
	IRAK-4 protein kinase inhibitor 2 is a potent interleukin-1 receptor-associated kinase-4 (IRAK-4) inhibitor(IC50 = 4 μM).		IRAK
T11673	IRAK4-IN-4		IRAK , cGAS
	IRAK4-IN-4 (compound 15) inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhibitor, has an IC50 of 2.8 nM.		IRAK , cGAS
T2457	IRAK-1-4 Inhibitor I	IRAK-1/4 Inhibitor I,IRAK-1/4 Inhibitor	IRAK
	IRAK-1-4 Inhibitor I is a dual inhibitor of IRAK4 and IRAK1.		IRAK
T22338	2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide	GDC046	Others , JAK
	2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046), a potent lead analog, has good kinase selectivity, physicochemical properties and pharmacokinetic profile.		Others , JAK
T4140	IRAK4-IN-1		IRAK
	IRAK4-IN-1 is an interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor with an IC50 of 7 nM.		IRAK
T9043	AS1810722		P450 , STAT
	AS1810722, a fused bicyclic pyrimidine derivative, is an orally active and potent inhibitor of STAT6, demonstrating an IC50 of 1.9 nM. It exhibits effective inhibition of CYP3A4, positioning it as a promising candidate f...		P450 , STAT
T4299	AS-2444697		IRAK
	AS-2444697 is an inhibitor of IRAK-4 (C50 = 21 nM). AS-2444697 exhibits renoprotective effects through anti-inflammatory action. AS-2444697 potently inhibits human and rat IRAK-4 activity.		IRAK
T14367	AZ1495		IRAK , CDK , Haspin Kinase
	AZ1495 is an oral active inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4), with IC50 values of 5 nM and 23 nM for IRAK4 and IRAK1, respectively. Which Shows activity in treatment of mutant MYD88L265P diffu...		IRAK , CDK , Haspin Kinase
T5354	IRAK4-IN-7	CA-4948	IRAK
	IRAK4-IN-7 (CA-4948) is a selective and potent IRAK4 kinase inhibitor with in vivo activity in a TLR4-induced cytokine release model.		IRAK
T3965	Fevipiprant	QAW039,NVP-QAW039	GPR , Prostaglandin Receptor
	Fevipiprant (NVP-QAW039) is a selective, potent, reversible competitive CRTh2 antagonist.		GPR , Prostaglandin Receptor
T63089	(R)-IL-17 modulator 4
	(R)-IL-17 modulator 4 is the R-configured form of IL-17 modulator 4 and is a prodrug of IL-17 modulator 1. IL-IL-17 modulator 1 is a potent, orally active IL-17 modulator.
T25465	GS143	GS-143,GS 143	IκB/IKK , E1/E2/E3 Enzyme , NF-κB
	GS143 is a selective IκBα ubiquitination inhibitor with an IC50 of 5.2 μM for SCFβTrCP1-mediated IκBα ubiquitylation. GS143 suppresses NF-κB activation and transcription of target genes and does not inhibit protea...		IκB/IKK , E1/E2/E3 Enzyme , NF-κB
T0117	Suplatast (Tosilate)	IPD 1151T,Suplatast tosilate,Suplatast Tosylate	IL Receptor , Interleukin
	Suplatast Tosilate (IPD 1151T) is a novel capsular anti-asthmatic drug. It ( IC50 above 100 μM) inhibits both IgE production, IL-4 and IL-5 synthesis.		IL Receptor , Interleukin
T9840	Ataquimas		Immunology/Inflammation related
	Ataquimast inhibits IL-5 secretion along with that of TNF-a, IL-4 and GM-CSF from human cells.		Immunology/Inflammation related
T24984	5J-4		Calcium Channel
	5J-4 is a potent a blocker of calcium release-activated calcium (CRAC) channel and store-operated calcium entry (SOCE). 5J-4 reduces the production of IL-17 and decreases the expression of RORα and RORγt.		Calcium Channel
T76773	Rolinsatamab		IL Receptor
	Rolinsatamab is a fully humanized selective monoclonal antibody that is a potent dual inhibitor of IL-4 and IL-13. Rolinsatamab chimeric antigen receptor sequence T cells. Rolinsatamab can be used to prevent and treat im...		IL Receptor
T13666	Dupilumab	REGN-668,SAR-231893	IL Receptor
	Dupilumab (REGN-668) is a systemic immunomodulator for AD. Dupilumab is a fully human monoclonal antibody against the alpha subunit of the interleukin-4 receptor, which inhibits downstream signaling of IL-4 and IL-13 and...		IL Receptor
T77426	Pascolizumab	SB-240683	IL Receptor
	Pascolizumab (SB-240683) is a humanized monoclonal antibody against IL-4. Pascolizumab has asthmatic effects and can be used to study allergic rhinitis.		IL Receptor
T25150	BI-69A11	BI 69A11,(E)-3-(1H-Benzo[d]imidazol-2-yl)-1-(6-chloro-2-hydroxy-4-phenylquinolin-3-yl)prop-2-en-1-one	NF-κB , Akt
	BI-69A11 ((E)-3-(1H-Benzo[d]imidazol-2-yl)-1-(6-chloro-2-hydroxy-4-phenylquinolin-3-yl)prop-2-en-1-one) is a dual AKT and NFkB pathway inhibitor. It enhances the susceptibility of colon cancer cells to mda-7/IL-24-induce...		NF-κB , Akt
T77579	JC2-11		IL Receptor , Dehydrogenase , ROS , Caspase , NOD-like Receptor (NLR) , AIM2
	JC2-11 is an inhibitory compound for inflammation.JC2-11 inhibits the recruitment domain-containing proteins NLRC 4, atypical in melanoma 2 (AIM 2) and atypical (NC) inflammatory vesicles by disrupting reactive oxygen sp...
T0097	MRT67307	MRT67307 HCl	IκB/IKK , Autophagy
	Through its effects on ULK1 and ULK2, MRT67307 blocks autophagy. MRT67307 prevents the phosphorylation of IRF3 and the production of IFN-β and increases toll-like receptor-induced IL-10 and IL-1ra secretion in macrophage...		IκB/IKK , Autophagy
T12781	RV01		Others
	RV01 is a novel quinoline-substituted analogue of resveratrol that inhibits DNA damage, reduces ethanol-induced acetaldehyde dehydrogenase (ALDH2) mRNA expression, and has hydroxyl radical scavenging activity. rV01 reduc...		Others
T7672	MD2-TLR4-IN-1		TLR
	MD2-TLR4-IN-1 is a myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex inhibitor.		TLR
T9948	NecroX-7	LC-280126,LC28-0126,LC28 0126	NADPH-oxidase
	NecroX-7 (LC-280126) is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor. NecroX-7 can be used as an antidote to acetaminophen toxicity. NecroX-7 exerts a protective effect by preventing ...		NADPH-oxidase
T38294	4-Deoxypyridoxine hydrochloride		S1P Receptor
	4-Deoxypyridoxine (4-DPD) is a vitamin B6 antimetabolite with diverse biological activities. It inhibits transport of pyridoxine , pyridoxal, and pyridoxamine in and reduces growth of S. carlsbergensis cells. 4-DPD inhib...		S1P Receptor
T80610	Romilkimab	SAR156597
	Romilkimab (SAR156597) is a chimeric humanized immunoglobulin (Ig) antibody designed to specifically target interleukins 4 and 13 (IL-4 and IL-13) [1].
T26753	BC12-4
	BC12-4 is a novel potent inhibitor of IL-2 secretion, it has potent immunomodulatory activity.
T70107	Olcorolimus
	Olcorolimus inhibits single allergen-induced allergic inflammation such as eosinophilic and lymphocytic infiltration and mRNA expression for interleukin (IL)-4 and IL-5
T81098	Stapokibart	CM310
	Stapokibart (CM310), a humanized monoclonal antibody, selectively binds to IL-4Rα, inhibiting the cytokines IL-4 and IL-13 from interacting with their shared co-receptor subunit, IL-4Rα. This compound demonstrates cross-...
T70001	Pyrazinib
	Pyrazinib is a novel inhibitor of angiogenesis and metabolism of oesophageal adenocarcinoma (oac) radioresistance, significantly inhibiting the secretion of il-6, il-4, il-8 and il-13 cytokines from in oac radioresist...
T39342	4-Maleimidosalicylic acid
	4-Maleimidosalicylic acid is a polar maleimide compound that does not exhibit suppressive effects on IL-2 production in JURKAT T cells.
T63124	RORγt modulator 4
	RORγt modulator 4 is a RORγt modulator that regulates IL-17A production activity in cells derived from mouse spleen.
T77080	Manfidokimab
	Manfidokimab (AK120), an IgG4 monoclonal antibody targeting the interleukin 4 receptor alpha (IL-4Rα), demonstrates therapeutic efficacy as detailed in reference [1].
T68442	Desacetylravidomycin
	Desacetylravidomycin is a new inhibitor of IL-4 signal transduction, produced by Streptomyces sp. WK-6326.
T79256	DPP-4-IN-8
	DPP-4-IN-8 (compound 27) is a potent and selective inhibitor of dipeptidyl peptidase 4 (DPP4), with an inhibition constant (Ki) of 0.96 μM. It inhibits the dipeptidase activity of DPP4 in both Caco-2 and HepG-2 cells and...
T38008	KBC-007
	KBC-007 is a synthetic branched chain-containing analog of α-galactosylceramide (α-GalCer). It induces IL-4 and IFN-γ secretion by mouse splenocytes when used at a concentration of 0.5 ng/ml and IL-2 secretion by DN32.D3...
T81579	P2X7 receptor antagonist-4
	Compound 14a (P2X7 receptor antagonist-4) is a P2X7R antagonist with IC50 values of 64.7 nM in humans and 10.1 nM in mice. It inhibits the activation of the NLRP3 inflammasome, which subsequently reduces the expression o...
T81314	Rademikibart	CBP-201
	Rademikibart (CBP-201) is a human monoclonal antibody selective for IL-4Rα, exhibiting strong affinity with a KD of 20.7 pM for human IL-4Rα epitopes, without cross-reactivity to IL-4Rα from other species. It effectively...
T37554	Oleyl Anilide
	AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol. Oleyl analide (OA) is a weak inhibitor of acylCoA:cholesterol acyltransfera...
T73372	GNE-2256
	GNE-2256, also known as molecule 19, is an orally active compound that inhibits Interleukin 1 receptor-associated kinase 4 (IRAK4) with a K i of 1.4 nM and has an IL-6 inhibition concentration (IC50) of 190 nM.
T37590	ML 3403
	p38 MAPK inhibitor (IC50 = 0.38 μM). Inhibits the release of IL-1β and TNF-α in a peripheral blood mononuclear cell (PBMC) assay (IC50 values are 0.039 and 0.16 μM respectively). Laufer et al (2003) Novel substituted pyr...
T79362	COX-2/15-LOX-IN-4		Lipoxygenase
	COX-2/15-LOX-IN-4 (compound 5i) is a dual inhibitor with IC50 values of 0.075 μM for COX-2 and 1.97 μM for 15-LOX. It inhibits LPS-induced production of pro-inflammatory cytokines (IL-6, ROS) and exhibits targeted anti-i...		Lipoxygenase
T60366	Epinastine
	Epinastine (WAL801), a potent, selective, and orally-active antihistamine and mast cell stabilizer, functions as a histamine H1 receptor antagonist. It also inhibits IL-8 release from human eosinophils, showcasing antial...
T23028	MRT67307 HCl (1190378-57-4 free base)	MRT67307 HCl	Others
	MRT67307 is an inhibitor for TBK1, IKKε , MARK1-4 and NUAK1 with IC50 value of 19, 160, 27-52 and 230nM , respectively [1]. It is an inhibitor for ULK1and ULK2 with IC50 value of 45 and 38nM, respectively [2]. Also, it i...		Others
T35864	T-5342126
	T-5342126 is a toll-like receptor 4 (TLR4) antagonist.1It reduces LPS-induced production of nitric oxide (NO) in RAW 264.7 cells (IC50= 27.8 μM), as well as decreases LPS-induced IL-8, TNF-α, and IL-6 production in isola...
T35450	α-GalCer analog 8	α-GalCer analog 8,α-Galactosylceramide analog 8
	α-Galactosylceramide analog 8 (α-GalCer analog 8) is a triazole derivative of α-galactosylceramide. [1] It increases IL-2 secretion by DN32.D3 NKT hybridoma cells when co-cultured with CD1d-transfected RBL cells pre-load...

Compounds

IL-17 modulator 4 sulfate

IRAK-4 protein kinase inhibitor 2

Synonym: IRAK-1/4 Inhibitor I,IRAK-1/4 Inhibitor

Target: IRAK

2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide

Target: IRAK, CDK, Haspin Kinase

Synonym: QAW039,NVP-QAW039

Target: GPR, Prostaglandin Receptor

(R)-IL-17 modulator 4

Synonym: GS-143,GS 143

Target: IκB/IKK, E1/E2/E3 Enzyme, NF-κB

Suplatast (Tosilate)

T0117

Synonym: IPD 1151T,Suplatast tosilate,Suplatast Tosylate

Target: IL Receptor, Interleukin

Ataquimas

T9840

Synonym:

Target: Immunology/Inflammation related

5J-4

T24984

Synonym:

Target: Calcium Channel

Synonym: REGN-668,SAR-231893

Synonym: BI 69A11,(E)-3-(1H-Benzo[d]imidazol-2-yl)-1-(6-chloro-2-hydroxy-4-phenylquinolin-3-yl)prop-2-en-1-one

Target: IL Receptor, Dehydrogenase, ROS, Caspase, NOD-like Receptor (NLR), AIM2

MRT67307

T0097

Synonym: MRT67307 HCl

Target: IκB/IKK, Autophagy

Synonym: LC-280126,LC28-0126,LC28 0126

Target: NADPH-oxidase

4-Deoxypyridoxine hydrochloride

4-Maleimidosalicylic acid

P2X7 receptor antagonist-4

MRT67307 HCl (1190378-57-4 free base)

T23028

Synonym: MRT67307 HCl

Synonym: α-GalCer analog 8,α-Galactosylceramide analog 8

Target:

カタログ番号	製品名	別名	ターゲット
TN6722	Terminolic acid	2α,6β,23-trihydroxyl oleanolic acid	Antibacterial
	Terminolic acid (2α,6β,23-trihydroxyl oleanolic acid) is a pentacyclic triterpenoid glucoside isolated from Combretum racemosum, can inhibit the pro-inflammatory cytokines by binding to receptor active site of IL-1β and ...		Antibacterial
TN1416	Ayanin		IL Receptor , P450 , PARP , PDE
	Ayanin has vasorelaxant activity, it also may have the potential for use in treating allergic asthma.The IC(50) value of Ayanin (quercetin-3,7,4'-O-trimethylether) is 2.2microM for inhibiting interleukin (IL)-4 productio...		IL Receptor , P450 , PARP , PDE
TN1894	Luteolin-4'-O-glucoside	Luteolin-4'-glucoside,Luteolin-4-o-glucoside	IL Receptor
			IL Receptor
T2S0342	Armillarisin A		Others , Interleukin
	Armillarisin A enhancing the role of macrophages, inhibiting bacteria growth, improving the protein metabolism, and regulating liver function.		Others , Interleukin
T8280	Deacetylasperulosidic Acid	Desacetyl asperulosidic acid	IL Receptor , Interleukin
	Deacetylasperulosidic Acid is a natural compound of Morinda citrifolia fruit. It has antioxidant activity by increasing superoxide dismutase activity. It also prevents 4-nitroquinoline 1-oxide (4NQO) induced DNA damage i...		IL Receptor , Interleukin
T37280	PE(18:1(9Z)/0:0)		Endogenous Metabolite
	PE(18:1(9Z)/0:0) is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine. PE(18:1(9Z)/0:0) induces transient increases in intracellular calcium in PC12 rat neuronal cells in a ...		Endogenous Metabolite
T3859	Isomucronulatol	7,2'-Dihydroxy-3',4'-dimethoxyisoflavan	Others
	Isomucronulatol (7,2'-Dihydroxy-3',4'-dimethoxyisoflavan) is a natural product		Others
TJS0338	4-Methylesculetin	4-Methyl-6,7-dihydroxycoumarin,Methylesculetin	Antioxidant , Glutathione Peroxidase
	4-Methylesculetin (Methylesculetin) is one of the coumarin derivatives with great anti-oxidant and anti-inflammatory activities.		Antioxidant , Glutathione Peroxidase
T3829	Ginsenoside F3		Others , IFNAR , Interleukin
	Ginsenoside-F3 has immunoenhancing activity by regulating production and gene expression of type 1, type 2 cytokines in murine spleen cells. Ginsenoside-F3 enhances the NF-kappaB DNA binding activity induced by ConA in m...		Others , IFNAR , Interleukin
T4S0145	Corylifol A	Corylinin	hCE , STAT , UGT
	1. Corylifol A (Corylinin) displays cytotoxic activity against HepG2 and Hep3B hepatocellular carcinoma cell lines, with IC50 values of 4.6 and 13.5 ug/ml, respectively. 2. Corylifol A and Biochanin A can be the potentia...		hCE , STAT , UGT
T3398	Icaritin	Anhydroicaritin,Cycloicaritin	Apoptosis , JAK , STAT , Autophagy
	Icaritin (Anhydroicaritin) has hormone regulation activity and cardiovascular function improvement activity. Icaritin has anticancer activity, can induce S phase arrest and apoptosis, inhibit ENKL cell proliferation. Ica...		Apoptosis , JAK , STAT , Autophagy
T6S1917	Schisandrol B	Gomisin A,TJN-101,Besigomsin,Gamma-Schisandrin,Schizandrol B,Wuweizi alcohol-B	P450 , Reactive Oxygen Species , Autophagy
	1. Schisandrol B (Besigomsin) may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated NF-κB and MAPKs signaling pathways. 2. Schisandrol B has a...		P450 , Reactive Oxygen Species , Autophagy
T2S0843	Negletein	7-O-Methylbaicalein,Baicalein-7-methylether	IL Receptor , TNF , NOS , Interleukin
	1. Negletein (7-O-Methylbaicalein) has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. 2. Negletein as a neuroprotectant enhances the action of nerve growth factor and induces n...		IL Receptor , TNF , NOS , Interleukin
T38373	2-heptyl-3-hydroxy-4(1H)-Quinolone	2-heptyl-3-hydroxy-4(1H)-Quinolone,PQS,Pseudomonas Quinolone Signal	Others
	2-heptyl-3-hydroxy-4(1H)-Quinolone (Pseudomonas Quinolone Signal) is a quorum-sensing signalling molecule produced by Pseudomonas aeruginosa in response to increased cell density. It increases the expression of the lasB ...		Others
T6S1579	Monotropein	Monotropeine	Others
	1. Monotropein (Monotropeine) has antinociceptive action. 2. Monotropein has anti-apoptosis and anti-catabolic activity in chondrocytes. 3. Monotropein has anti-inflammatory action by inhibition of the expressions of inf...		Others
T5S2059	Glaucine		Calcium Channel , Dopamine Receptor , Influenza Virus , Adrenergic Receptor , PDE
	Glaucine has antitussive, antioxidative potential and antiviral activities, it may be an anti-arthritic agent, it can enhance LPS and zymosan-induced IL-10 production. Glaucine can inhibit the migration and invasion of h...
T4S2063	Tetrahydrocoptisine	STYLOPINE	ERK , p38 MAPK , NF-κB
	1. Tetrahydrocoptisine (STYLOPINE) has effective effects in suppressing inflammation. 2. Tetrahydrocoptisine possesses a protective effect on LPS-induced ALI through inhibiting of NF-κB signaling pathways, which may invo...		ERK , p38 MAPK , NF-κB
T6S1315	Oroxylin A	6-Methoxybaicalein,Baicalein 6-methyl ether	Virus Protease , HIF/HIF Prolyl-Hydroxylase , Autophagy
	1. Oroxylin A (Baicalein 6-methyl ether) has various anti-tumor effects including apoptosis, cell cycle arrest, drug-resistant reversion. 2. Oroxylin A possesses abilities of inhibiting the ATRA-induced IL-6 production v...		Virus Protease , HIF/HIF Prolyl-Hydroxylase , Autophagy
T2S2264	Linalool	Linalol,(±)-Linalool,Phantol	Apoptosis , IL Receptor , TNF , Endogenous Metabolite , iGluR
	1. Linalool (Linalol), a natural compound of the essential oils, has been shown to have antinociceptive, antimicrobial, and anti-inflammatory properties. 2. Linalool was protected against LPS/GalN-induced liver injury th...
T75694	Lacto-N-neotetraose
	Lacto-N-neotetraose (LNnT), an endogenous metabolite, inhibits TNF-α-induced IL-8 secretion in immature epithelial cells, exhibits anti-inflammatory activity, and enhances wound closure [1] [2] [4].

天然物製品

Terminolic acid

TN6722

Synonym: 2α,6β,23-trihydroxyl oleanolic acid

Target: Antibacterial

Ayanin

TN1416

Synonym:

Target: IL Receptor, P450, PARP, PDE

Luteolin-4'-O-glucoside

TN1894

Synonym: Luteolin-4'-glucoside,Luteolin-4-o-glucoside

Target: Others, Interleukin

Deacetylasperulosidic Acid

T8280

Synonym: Desacetyl asperulosidic acid

Target: IL Receptor, Interleukin

PE(18:1(9Z)/0:0)

T37280

Synonym:

Target: Endogenous Metabolite

Isomucronulatol

T3859

Synonym: 7,2'-Dihydroxy-3',4'-dimethoxyisoflavan

Target: Others

4-Methylesculetin

TJS0338

Synonym: 4-Methyl-6,7-dihydroxycoumarin,Methylesculetin

Target: Antioxidant, Glutathione Peroxidase

Ginsenoside F3

T3829

Synonym:

Target: Others, IFNAR, Interleukin

Corylifol A

T4S0145

Synonym: Corylinin

Target: hCE, STAT, UGT

Icaritin

T3398

Synonym: Anhydroicaritin,Cycloicaritin

Target: Apoptosis, JAK, STAT, Autophagy

Schisandrol B

T6S1917

Synonym: Gomisin A,TJN-101,Besigomsin,Gamma-Schisandrin,Schizandrol B,Wuweizi alcohol-B

Target: P450, Reactive Oxygen Species, Autophagy

Negletein

T2S0843

Synonym: 7-O-Methylbaicalein,Baicalein-7-methylether

Target: IL Receptor, TNF, NOS, Interleukin

2-heptyl-3-hydroxy-4(1H)-Quinolone

T38373

Synonym: 2-heptyl-3-hydroxy-4(1H)-Quinolone,PQS,Pseudomonas Quinolone Signal

Target: Others

Monotropein

T6S1579

Synonym: Monotropeine

Target: Calcium Channel, Dopamine Receptor, Influenza Virus, Adrenergic Receptor, PDE

Tetrahydrocoptisine

T4S2063

Synonym: STYLOPINE

Target: ERK, p38 MAPK, NF-κB

Oroxylin A

T6S1315

Synonym: 6-Methoxybaicalein,Baicalein 6-methyl ether

Target: Virus Protease, HIF/HIF Prolyl-Hydroxylase, Autophagy

Linalool

T2S2264

Synonym: Linalol,(±)-Linalool,Phantol

Target: Apoptosis, IL Receptor, TNF, Endogenous Metabolite, iGluR

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-02558	IL-4 Protein, Mouse, Recombinant	Mouse	E. coli
	Interleukin-4, also known as IL4, is a secreted protein that belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation. It e...
TMPY-01862	IL-4 Protein, Human, Recombinant	Human	E. coli
	Interleukin-4, also known as IL4, is a secreted protein that belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation. It e...
TMPJ-00035	IL-4 Protein, Human, Recombinant (His)	Human	Human Cells
	Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal ce...
TMPJ-00387	IL-4R alpha Protein, Mouse, Recombinant (hFc)	Mouse	Human Cells
	Interleukin-4 receptor subunit alpha(IL-4RA), alos known as Soluble IL-4 receptor subunit alpha, belongs to the type I cytokine receptor family and type 4 subfamily. It expressed in both Th1 and Th2 cells. It functions a...
TMPY-05277	IL-4R Protein, Human, Recombinant (hFc)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-01055	IL-4R Protein, Human, Recombinant (His)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-00853	IL-1RA Protein, Human, Recombinant	Human	E. coli
	Interleukin-1 receptor antagonist (IL-1RA) also known as IL1RN is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A), and interleukin 1, beta (IL1B), and mo...
TMPY-02603	STAT6 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced tyrosine phosphorylation and mediates most of the IL-4-induced gene expression. STAT6...
TMPY-03624	IL-4 Protein, Mouse, Recombinant (Q136D, Y139D, His)	Mouse	Baculovirus-Insect Cells
	Interleukin-4, also known as IL4, is a secreted protein that belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation. It e...
TMPJ-00034	IL-4 Protein, Human, Recombinant (hFc)	Human	Human Cells
	Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal ce...
TMPK-00919	IL-4 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Interleukin-4, also known as IL4, is a secreted protein which belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation.In t...
TMPJ-00850	ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)	Mouse	Human Cells
	ST2, also called IL-1 R4, is an Interleukin-1 receptor family glycoprotein that plays a role in Th2 immune responses. ST2 is expressed on the surface of mast cells, activated Th2 cells, macrophages, and cardiac myocytes....
TMPY-01258	IL-13RA1 Protein, Human, Recombinant (His)	Human	HEK293
	Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha,...
TMPK-00034	IL-4 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	Interleukin-4, also known as IL4, is a secreted protein which belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation.In t...
TMPK-00035	IL-4 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Interleukin-4, also known as IL4, is a secreted protein which belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation.In t...
TMPY-02926	IL-2RG Protein, Human, Recombinant (hFc)	Human	HEK293
	The common gamma chain (γc) (or CD132), also known as interleukin-2 receptor subunit gamma or IL2RG, is a member of the type I cytokine receptor family expressed on most lymphocyte (white blood cell) populations, and its...
TMPY-01170	IL-13RA1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha,...
TMPY-00850	ST2/IL-1 RL1 Protein, Human, Recombinant	Human	HEK293
	IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn...
TMPY-00849	ST2/IL-1 RL1 Protein, Human, Recombinant (hFc)	Human	HEK293
	IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn...
TMPY-01359	ST2/IL-1 RL1 Protein, Human, Recombinant (His)	Human	HEK293
	IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn...
TMPY-06577	IL-4R Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-01033	IL-32 Protein, Human, Recombinant (isoform alpha, His)	Human	HEK293
	IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathw...
TMPY-05111	IL-4R Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-00852	IL-1RA Protein, Human, Recombinant (hFc)	Human	HEK293
	Interleukin-1 receptor antagonist (IL-1RA) also known as IL1RN is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A), and interleukin 1, beta (IL1B), and mo...
TMPY-01108	IL-10R beta/IL-10RB Protein, Human, Recombinant (His & hFc)	Human	HEK293
	Interleukin 10 receptor, beta subunit (IL10RB/IL-10RB) also known as Cytokine receptor family 2 member 4, Interleukin-10 receptor subunit 2, and cytokine receptor family II, member 4, is a subunit for the interleukin-10 ...
TMPY-01236	IL-10R beta/IL-10RB Protein, Human, Recombinant (His)	Human	HEK293
	Interleukin 10 receptor, beta subunit (IL10RB/IL-10RB) also known as Cytokine receptor family 2 member 4, Interleukin-10 receptor subunit 2, and cytokine receptor family II, member 4, is a subunit for the interleukin-10 ...
TMPJ-00076	IL-28B Protein, Human, Recombinant	Human	Human Cells
	Interleukin-28B, also known as Cytokine Zcyto22, Interferon lambda-3, Interferon lambda-4, IFNL3, IFNL4, ZCYTO22 and IL28B, is a secreted cytokine which belongs to the IL-28/IL-29 family. IL-28 has also been shown to pla...
TMPK-00272	IL-13RA1 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Two type 1 membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha,...
TMPK-00273	IL-13Ra1 Protein, Human, Recombinant (hFc)	Human	HEK293
	Two type 1 membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha,...
TMPY-02790	IL-4 Protein, Canine, Recombinant	Canine	E. coli
	Interleukin-4, also known as IL4, is a secreted protein that belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation. It e...
TMPY-02325	IL-10R beta/IL-10RB Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Interleukin 10 receptor, beta subunit (IL10RB/IL-10RB) also known as Cytokine receptor family 2 member 4, Interleukin-10 receptor subunit 2, and cytokine receptor family II, member 4, is a subunit for the interleukin-10 ...
TMPY-02324	IL-10R beta/IL-10RB Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Interleukin 10 receptor, beta subunit (IL10RB/IL-10RB) also known as Cytokine receptor family 2 member 4, Interleukin-10 receptor subunit 2, and cytokine receptor family II, member 4, is a subunit for the interleukin-10 ...
TMPK-00986	IL-2 R gamma/CD132 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232...
TMPK-00987	IL-2 R gamma/CD132 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated	Cynomolgus	HEK293
	The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232...
TMPK-00239	IL-2 R gamma/CD132 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232...
TMPJ-00849	ST2/IL-1 RL1 Protein, Mouse, Recombinant (V192A, hFc)	Mouse	Human Cells
	ST2, also called IL-1 R4, is an Interleukin-1 receptor family glycoprotein that plays a role in Th2 immune responses. ST2 is expressed on the surface of mast cells, activated Th2 cells, macrophages, and cardiac myocytes....
TMPY-06590	IL-13RA1 Protein, Human, Recombinant (aa 1-343, hFc)	Human	HEK293
	Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha,...
TMPY-06579	IL-13RA1 Protein, Human, Recombinant(aa 1-343, His & Avi), Biotinylated	Human	HEK293
	Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha,...
TMPK-00238	IL-2 R gamma/CD132 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232...
TMPY-01074	IL-13RA1 Protein, Human, Recombinant (His & hFc)	Human	HEK293
	Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha,...
TMPY-05123	IL-13RA1 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha,...
TMPH-03499	IL-4 Protein, Sheep, Recombinant (His)	Sheep	Yeast
	Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both...
TMPH-02457	IL-4 Protein, Mesocricetus auratus, Recombinant (His)	Mesocricetus auratus	Yeast
	Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both...
TMPH-02387	IL-4 Protein, Lama glama, Recombinant (His)	Lama glama	Yeast
	Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both...
TMPJ-00270	IL-13RA1 Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	Human Cells
	Interleukin-13 receptor subunit alpha-1(IL-13RA1), also known as NR4, belongs to the hemopoietin receptor family. Interleukin-13 receptor is a complex of IL4R, IL13RA1, and possibly other components. It interacts with TR...
TMPY-06359	IL-2RG Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	The common gamma chain (γc) (or CD132), also known as interleukin-2 receptor subunit gamma or IL2RG, is a member of the type I cytokine receptor family expressed on most lymphocyte (white blood cell) populations, and its...
TMPY-05692	IL-2RG Protein, Human, Recombinant (His)	Human	HEK293
	The common gamma chain (γc) (or CD132), also known as interleukin-2 receptor subunit gamma or IL2RG, is a member of the type I cytokine receptor family expressed on most lymphocyte (white blood cell) populations, and its...
TMPY-05432	IL-13RA1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha,...
TMPY-05795	IL-13RA1 Protein, Mouse, Recombinant (mFc)	Mouse	HEK293
	Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha,...
TMPH-03498	IL-4 Protein, Sheep, Recombinant (B2M & His & Myc)	Sheep	E. coli
	Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both...
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IL-4 Protein, Mouse, Recombinant

TMPY-02558

Species: Mouse

Expression System: E. coli

IL-4 Protein, Human, Recombinant

TMPY-01862

Species: Human

Expression System: E. coli

IL-4 Protein, Human, Recombinant (His)

TMPJ-00035

Species: Human

Expression System: Human Cells

IL-4R alpha Protein, Mouse, Recombinant (hFc)

TMPJ-00387

Species: Mouse

Expression System: Human Cells

IL-4R Protein, Human, Recombinant (hFc)

TMPY-05277

Species: Human

Expression System: HEK293

IL-4R Protein, Human, Recombinant (His)

TMPY-01055

Species: Human

Expression System: HEK293

IL-1RA Protein, Human, Recombinant

TMPY-00853

Species: Human

Expression System: E. coli

STAT6 Protein, Human, Recombinant (His)

TMPY-02603

Species: Human

Expression System: Baculovirus-Insect Cells

IL-4 Protein, Mouse, Recombinant (Q136D, Y139D, His)

TMPY-03624

Species: Mouse

Expression System: Baculovirus-Insect Cells

IL-4 Protein, Human, Recombinant (hFc)

TMPJ-00034

Species: Human

Expression System: Human Cells

IL-4 Protein, Cynomolgus, Recombinant (His)

TMPK-00919

Species: Cynomolgus

Expression System: HEK293

ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)

TMPJ-00850

Species: Mouse

Expression System: Human Cells

IL-13RA1 Protein, Human, Recombinant (His)

TMPY-01258

Species: Human

Expression System: HEK293

IL-4 Protein, Human, Recombinant (His & Avi)

TMPK-00034

Species: Human

Expression System: HEK293

IL-4 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00035

Species: Human

Expression System: HEK293

IL-2RG Protein, Human, Recombinant (hFc)

TMPY-02926

Species: Human

Expression System: HEK293

IL-13RA1 Protein, Mouse, Recombinant (His)

TMPY-01170

Species: Mouse

Expression System: HEK293

ST2/IL-1 RL1 Protein, Human, Recombinant

TMPY-00850

Species: Human

Expression System: HEK293

ST2/IL-1 RL1 Protein, Human, Recombinant (hFc)

TMPY-00849

Species: Human

Expression System: HEK293

ST2/IL-1 RL1 Protein, Human, Recombinant (His)

TMPY-01359

Species: Human

Expression System: HEK293

IL-4R Protein, Human, Recombinant (His & Avi), Biotinylated

TMPY-06577

Species: Human

Expression System: HEK293

IL-32 Protein, Human, Recombinant (isoform alpha, His)

TMPY-01033

Species: Human

Expression System: HEK293

IL-4R Protein, Human, Recombinant (His), Biotinylated

TMPY-05111

Species: Human

Expression System: HEK293

IL-1RA Protein, Human, Recombinant (hFc)

TMPY-00852

Species: Human

Expression System: HEK293

IL-10R beta/IL-10RB Protein, Human, Recombinant (His & hFc)

TMPY-01108

Species: Human

Expression System: HEK293

IL-10R beta/IL-10RB Protein, Human, Recombinant (His)

TMPY-01236

Species: Human

Expression System: HEK293

IL-28B Protein, Human, Recombinant

TMPJ-00076

Species: Human

Expression System: Human Cells

IL-13RA1 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00272

Species: Human

Expression System: HEK293

IL-13Ra1 Protein, Human, Recombinant (hFc)

TMPK-00273

Species: Human

Expression System: HEK293

IL-4 Protein, Canine, Recombinant

TMPY-02790

Species: Canine

Expression System: E. coli

IL-10R beta/IL-10RB Protein, Mouse, Recombinant (His)

TMPY-02325

Species: Mouse

Expression System: HEK293

IL-10R beta/IL-10RB Protein, Mouse, Recombinant (hFc)

TMPY-02324

Species: Mouse

Expression System: HEK293

IL-2 R gamma/CD132 Protein, Cynomolgus, Recombinant (His)

TMPK-00986

Species: Cynomolgus

Expression System: HEK293

IL-2 R gamma/CD132 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated

TMPK-00987

Species: Cynomolgus

Expression System: HEK293

IL-2 R gamma/CD132 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00239

Species: Human

Expression System: HEK293

ST2/IL-1 RL1 Protein, Mouse, Recombinant (V192A, hFc)

TMPJ-00849

Species: Mouse

Expression System: Human Cells

IL-13RA1 Protein, Human, Recombinant (aa 1-343, hFc)

TMPY-06590

Species: Human

Expression System: HEK293

IL-13RA1 Protein, Human, Recombinant(aa 1-343, His & Avi), Biotinylated

TMPY-06579

Species: Human

Expression System: HEK293

IL-2 R gamma/CD132 Protein, Human, Recombinant (His & Avi)

TMPK-00238

Species: Human

Expression System: HEK293

IL-13RA1 Protein, Human, Recombinant (His & hFc)

TMPY-01074

Species: Human

Expression System: HEK293

IL-13RA1 Protein, Human, Recombinant (His), Biotinylated

TMPY-05123

Species: Human

Expression System: HEK293

IL-4 Protein, Sheep, Recombinant (His)

TMPH-03499

Species: Sheep

Expression System: Yeast

IL-4 Protein, Mesocricetus auratus, Recombinant (His)

TMPH-02457

Species: Mesocricetus auratus

Expression System: Yeast

IL-4 Protein, Lama glama, Recombinant (His)

TMPH-02387

Species: Lama glama

Expression System: Yeast

IL-13RA1 Protein, Mouse, Recombinant (His & Avi), Biotinylated

TMPJ-00270

Species: Mouse

Expression System: Human Cells

IL-2RG Protein, Human, Recombinant (His & Avi), Biotinylated

TMPY-06359

Species: Human

Expression System: HEK293

IL-2RG Protein, Human, Recombinant (His)

TMPY-05692

Species: Human

Expression System: HEK293

IL-13RA1 Protein, Mouse, Recombinant (hFc)

TMPY-05432

Species: Mouse

Expression System: HEK293

IL-13RA1 Protein, Mouse, Recombinant (mFc)

TMPY-05795

Species: Mouse

Expression System: HEK293

IL-4 Protein, Sheep, Recombinant (B2M & His & Myc)

TMPH-03498

Species: Sheep

Expression System: E. coli

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カタログ番号	製品名
L8720	Pyroptosis Compound Library	1066 compounds
	1066 types of active small molecules associated with pyroptosis for high-throughput and high-content screening.
L7600	Chemokine Inhibitor Library	59 compounds
	A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening;

ライブラリー

Pyroptosis Compound Library

L8720

Compounds: 1066

Chemokine Inhibitor Library

L7600

Compounds: 59