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Search Results for " Malignant "

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103

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天然化合物

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T8452	Dantrolene		Others
	Dantrolene is a postsynaptic muscle relaxant by inhibiting Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors.		Others
T22223	3PO		Glucokinase , Autophagy
	3PO is a small-molecule inhibitor of PFKFB3 (IC50: 22.9 μM), inhibiting the proliferation of several human malignant hematopoietic and adenocarcinoma cell lines (IC50: 1.4-24 μM). It suppresses glucose uptake, and decrea...		Glucokinase , Autophagy
T14214	AMG 511		PI3K
	AMG 511 is a potent and orally available pan inhibitor of class I PI3Ks(Kis of 4 nM, 6 nM, 2 nM and 1 nM for PI3Kα, β, δ and γ, respectively). It exhibits anti-tumor activity in mouse glioblastoma xenograft model[1]. AMG...		PI3K
T1973	PFI-4	PFI4	Epigenetic Reader Domain
	PFI-4 is a potent and selective and cell-permeable BRPF1 bromodomain inhibitor.		Epigenetic Reader Domain
T2379	UNC1215		Apoptosis , Epigenetic Reader Domain , Histone Methyltransferase
	UNC1215, an effective and specific MBT (malignant brain tumor) antagonist, binds L3MBTL3 (IC50/Kd: 40/120 nM). The selectivity of UNC1215 for L3MBTL3 is 50-fold higher versus other members of the human MBT family.
T9954	K-975		Others
	K-975 is a highly selective, orally active TEAD inhibitor, effectively inhibiting protein-protein interactions between TEAD and YAP1/TAZ.		Others
T1120	Dacarbazine	Imidazole Carboxamide,DTIC-Dome	Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
	Dacarbazine (DTIC-Dome) is an antineoplastic agent. It has significant activity against melanomas.
T38050	CP-609754		Transferase
	CP-609754 (LNK-754) is a potent and reversible farnesyltransferase inhibitor with potential anticancer activity.The IC50 for inhibiting farnesylation of recombinant human H-Ras is 0.57 ng/mL and recombinant K-Ras is 46 n...		Transferase
T21505	Suberoyl bis-hydroxamic acid	SBHA,Suberohydroxamic acid	Apoptosis , HDAC
	Suberoyl bis-hydroxamic acid (SBHA) is a Histone deacetylase (HDAC) inhibitor. HDAC is required for transcriptional modulation, cell cycle regulation and development. It is an enzyme that deacetylates lysine residues on ...		Apoptosis , HDAC
T16699	PYZD-4409		Others , E1/E2/E3 Enzyme
	PYZD-4409 is a selective UBA1 inhibitor with an IC50 of 20 μM. PYZD-4409 induces cell death in malignant cells and is preferentially cytotoxic to malignant cells over normal hematopoietic cells.		Others , E1/E2/E3 Enzyme
TNU0123	5-Methoxyuridine	Mo5U	Apoptosis
	5-Methoxyuridine (Mo5U) is a purine nucleoside analog with a broad spectrum of antitumor activity, targeting malignant tumors of the inert lymphatic system and inducing apoptosis.5-Methoxyuridine's anticancer mechanism i...		Apoptosis
T67839	HG106		Others
	HG106, which is anti-inflammatory and may be used to treat the growth of diseases such as malignant tumours caused by mutations in the RAS gene., which is anti-inflammatory and may be used to treat the growth of diseases...		Others
T76815	Lexatumumab	ETR2-ST01,DR5 mAB,HGS-ETR 2	Apoptosis
	Lexatumumab (GHS-ETR 2) is a human excitatory monoclonal antibody targeting TRAIL receptor 2 that has anticancer activity and induces apoptosis in malignant mesothelioma. Lexatumumab can be used to study malignant pleura...		Apoptosis
T8762	SW106065	SW-106065	Apoptosis
	SW106065 is a novel pharmacologic inducer of apoptosis in MPNST (malignant peripheral nerve sheath tumors).SW106065 is an apoptosis inducer in malignant peripheral nerve sheath tumors (MPNST). It inhibits ATP consumption...		Apoptosis
T7491	6-O-Methyl Guanosine		Nucleoside Antimetabolite/Analog
	6-O-Methyl Guanosine inhibit colony-forming ability in a malignant xeroderma pigmentosum cell line.		Nucleoside Antimetabolite/Analog
TNU0436	2-Thiocytidine		Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
	2-Thiocytidine is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and has a broad spectrum of antitumor activity.2-Thiocytidine induces apoptosis by inhibiting DNA synthesis.2-Thioc...
T8654	Plx-4032	Vemurafenib	Raf
	Plx-4032 (Vemurafenib) is a small-molecule B-Raf inhibitor for the potential treatment of malignant melanoma.		Raf
T16871	Semustine		DNA Alkylator/Crosslinker
	Semustine, a DNA alkylating agent, is a cancer chemotherapy compound that is nephrotoxic in patients with malignant melanoma receiving adjuvant chemotherapy for the adjuvant treatment of leukemia.		DNA Alkylator/Crosslinker
TNU0022	6-Azauridine	6-Azuridine	Apoptosis
	6-Azauridine (6-Azuridine) is a purine nucleoside analog with a broad spectrum of antitumor activity, targeting malignant tumors of the inert lymphatic system and inducing apoptosis.6-Azuridine's anticancer mechanism is ...		Apoptosis
T9104	TJ191		Apoptosis
	TJ191 is a selective anti-cancer agent, targeting low TβRIII-expressing malignant T-cell leukemia/lymphoma cells.		Apoptosis
T77689	(1R,2R)-(-)-1,2-Diaminocyclohexane	(1R,2R)-Cyclohexane-1,2-diamin	Others
	(1R,2R)-(-)-1,2-Diaminocyclohexane ((1R,2R)-Cyclohexane-1,2-diamin) has anticancer and antitumor activity and can be used to study malignant tumors.		Others
T2068	(Rac)-LB-100		Phosphatase
	LB-100, a novel Protein Phosphatase 2A (PP2A) inhibitor, sensitizes malignant meningioma cells to the therapeutic effects of radiation		Phosphatase
T2073	GSK2636771	GSK 2636771,GSK-2636771	PI3K
	GSK2636771, an effective, specific, orally bioavailable, PI3Kβ inhibitor, has been used in cancer, lymphoma, solid neoplasm, recurrent solid neoplasm, and advanced malignant neoplasm.		PI3K
T77118	Plozalizumab	MLN-1202	CCR
	Plozalizumab (MLN-1202) is a humanized selective and potent anti-CCR2 antibody.Plozalizumab has antitumor activity.Plozalizumab is used in the study of malignant melanoma.		CCR
T74698	RMC-6236		Ras
	RMC-6236 is a RAS(ON)MULTI inhibitor with anticancer activity and is used in the study of advanced malignant solid tumors and colorectal cancer.		Ras
T5341	WYC-209	WYC209	Apoptosis , Retinoid Receptor , Autophagy
	WYC-209 inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs, IC50: 0.19 uM). It targets the retinoic acid receptor (RAR).		Apoptosis , Retinoid Receptor , Autophagy
T2252	UNC 669	UNC669	Epigenetic Reader Domain
	UNC 669 is an effective and specific MBT (malignant brain tumor) inhibitor with IC50 of 4.2/3.1 uM for L3MBTL1/3.		Epigenetic Reader Domain
T2699	BMS 777607	BMS777607,BMS-777607,BMS 817378	c-Met/HGFR , TAM Receptor
	BMS 777607 (BMS 817378) is a Met-related inhibitor for c-Met/Axl/Ron/Tyro3 (IC50: 3.9/1.1/1.8/4.3 nM). BMS-777607 has been investigated for the basic science of Malignant Solid Tumour.		c-Met/HGFR , TAM Receptor
T4356	POL1-IN-1	Compound 3A	DNA/RNA Synthesis
	POL1-IN-1 (Compound 3A) can effectively inhibit the transcription of RNA polymerase I in the A375 malignant melanoma cell line but has no effect on polymerase II.		DNA/RNA Synthesis
T83970	IMMH 010 maleate	YPD-30 maleate	PD-1/PD-L1
	IMMH 010 maleate (YPD-30 maleate) is an orally available programmed cell death ligand 1 inhibitor with potential antitumor activity for the study of neurological disorders and advanced malignant solid tumors.		PD-1/PD-L1
T21294	Polmacoxib	CG-100649,CG100649,CG 100649	COX , Carbonic Anhydrase
	Polmacoxib (CG 100649) is a first-in-class NSAID drug candidate, is a dual inhibitor of carbonic anhydrase (CA) and COX-2. Polmacoxib inhibits premalignant and malignant colorectal lesions in mouse models, partly through...		COX , Carbonic Anhydrase
T9919	Alemtuzumab		Others
	Alemtuzumab is a humanized monoclonal antibody against CD52 an antigen found on the surface of normal and malignant lymphocytes.		Others
T9089	FTO-IN-1	UUN44923	Others
	UUN44923 is a FTO inhibitor. It may be useful for treating diseases assocd. with FTO targets, obesity, metabolic syndrome (MS) , type 2 diabetes (T2D) , Alzheimer's diseases, breast cancers, small- cell lung cancers, a h...		Others
T11717	JHU395		Apoptosis
			Apoptosis
T21017	5'-Amino-5'-deoxyadenosine	5' Amino 5' deoxyadenosine,5'Amino5'deoxyadenosine,Nsc 238990,NH2dAdo	Apoptosis , Adenosine Receptor
	5'-Amino-5'-deoxyadenosine (NH2dAdo) is an adenosine kinase inhibitor targeting malignant tumors of the inert lymphatic system with antitumor and anticancer effects.The anticancer mechanism of 5'-Amino-5'-deoxyadenosine ...		Apoptosis , Adenosine Receptor
T76685	Glofitamab	RO7082859,RG 6026,CD20-TCB	Others
	Glofitamab (RO7082859) is a novel bivalent antibody directed against CD20-binding T cells.Glofitamab promotes T cell proliferation and activation and tumor cell killing by binding to CD20 on malignant cells.Glofitamab ca...		Others
T35392	Tiragolumab	RO 7092284,RG6058-10,MTIG-7192A,RG6058-11,RG-6058	Others
	Tiragolumab(MTIG-7192A) is a monoclonal antibody that targets T-cell immunoglobulin and the ITIM structural domain (TIGIT).Tiragolumab is often used in combination with the PD-L1 inhibitor, Atezolizumab, for the treatmen...		Others
TNU0839	1,4-Dideoxy-1,4-epithio-D-ribitol		Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
	1,4-Dideoxy-1,4-epithio-D-ribitol is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and possesses a broad spectrum of antitumor activity.1,4-Dideoxy-1,4-epithio-D-ribitol induces a...
TNU0168	2'-Deoxy-2'-fluoro-beta-D-arabinoguanosine		Apoptosis
	2'-Deoxy-2'-fluoro-beta-D-arabinoguanosine is a purine nucleoside analog with a broad spectrum of antitumor activity, targeting malignant tumors of the inert lymphatic system and inducing apoptosis. The anticancer mechan...		Apoptosis
T64167	Ifebemtinib	IN-10018,BI-853520	FAK
	Ifebemtinib (BI-853520) is an orally active and potent inhibitor of adhesion plaque kinase (FAK) (IC50=1 nM) with anti-tumour activity that inhibits globule formation and in situ tumour growth in malignant pleural mesoth...		FAK
T0189L	Pemetrexed disodium	LY-231514,LY231514 disodium,Pemetrexed	Apoptosis , DHFR , DNA/RNA Synthesis , Antifolate , Autophagy
	Pemetrexed disodium (LY-231514) is a parenterally administered folate antagonist and antineoplastic agent, used in the treatment of non-small cell lung cancer and malignant mesothelioma. Pemetrexed disodium therapy has b...
T60440	Antiviral agent 17
	Antiviral agent 17 (Compound 4) is an anti-infection agent that retains its strong antiviral effect in a human replicon assay with an EC50 of 0.015 μM. Antiviral agent 17 shows good antiviral activity against murine noro...
TNU0630	2'-O-Methyl-5-iodouridine	5-Iodo-2'-O-methyluridine
	2'-O-Methyl-5-iodouridine (5-Iodo-2'-O-methyluridine) is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and possesses a broad spectrum of antitumor activity. The anticancer mechani...
T0272	Nilutamide	RU23908	Androgen Receptor
	Nilutamide (RU23908), an antineoplastic hormonal agent, is mainly used in the treatment of prostate Y. Nilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors, but not for estrogen, progesto...		Androgen Receptor
T76692	Mosunetuzumab	BTCT-4465A	Others
	Mosunetuzumab (BCT-4465A) is a humanized antibody based on immunoglobulin G1 that targets CD20 (B cells) and CD3 (T cells). Mosunetuzumab redirects T cells to engage and eliminate malignant B cells and can be used to stu...		Others
T34281	Relamorelin	BIM28131,RM 131,BIM-28131,BIM-28163,BIM 28163,BIM28163,BIM 28131	GHSR
	Relamorelin (RM-131), a selective and potent growth hormone-releasing peptide/growth hormone secretagogue receptor (GHSR) agonist, is a potent growth hormone-releasing peptide mimetic with a high affinity for the GHS-1a ...		GHSR
T38960	QL-X-138		Virus Protease , MNK , BTK
	QL-X-138 is a potent and selective BTK and MNK dual kinase inhibitor that binds covalently to BTK and non-covalently to MNK.The IC 50 s of QL-X-138 against BTK, MNK1 and MNK2 kinases are 9.4 nM, 107.4 nM and 26 nM, respe...		Virus Protease , MNK , BTK
T38951	Isatuximab	SAR-650984,hu38SB19,Isatuximab-irfc	Apoptosis , CD38
	Isatuximab is a monoclonal antibody targeting the transmembrane receptor and extracellular enzyme CD38 in malignant cells of the hematological system and is a highly expressed protein in multiple myeloma. Isatuximab has ...		Apoptosis , CD38
T3626	Acalabrutinib	ACP-196	BTK
	Acalabrutinib (ACP-196), also known as ACP-196, is an orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity. Upon administration, ACP-196 inhibits the activity of BTK and pre...		BTK
T36944	Ara-G		Nucleoside Antimetabolite/Analog
	Ara-G is an analog of the nucleoside guanosine and an active metabolite of nelarabine .1,2 Ara-G accumulates in T lymphoblasts and malignant T-lymphoid cells, where it is phosphorylated to produce ara-GTP and incorporate...		Nucleoside Antimetabolite/Analog

Compounds

Target: Glucokinase, Autophagy

Target: Epigenetic Reader Domain

UNC1215

T2379

Synonym:

Target: Apoptosis, Epigenetic Reader Domain, Histone Methyltransferase

Synonym: Imidazole Carboxamide,DTIC-Dome

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

Suberoyl bis-hydroxamic acid

T21505

Synonym: SBHA,Suberohydroxamic acid

Target: Apoptosis, HDAC

PYZD-4409

T16699

Synonym:

Target: Others, E1/E2/E3 Enzyme

Synonym: ETR2-ST01,DR5 mAB,HGS-ETR 2

Target: Nucleoside Antimetabolite/Analog

2-Thiocytidine

TNU0436

Synonym:

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

Target: DNA Alkylator/Crosslinker

(1R,2R)-(-)-1,2-Diaminocyclohexane

T77689

Synonym: (1R,2R)-Cyclohexane-1,2-diamin

Synonym: GSK 2636771,GSK-2636771

Target: Apoptosis, Retinoid Receptor, Autophagy

UNC 669

T2252

Synonym: UNC669

Target: Epigenetic Reader Domain

BMS 777607

T2699

Synonym: BMS777607,BMS-777607,BMS 817378

Target: c-Met/HGFR, TAM Receptor

POL1-IN-1

T4356

Synonym: Compound 3A

Target: DNA/RNA Synthesis

IMMH 010 maleate

T83970

Synonym: YPD-30 maleate

Target: PD-1/PD-L1

Polmacoxib

T21294

Synonym: CG-100649,CG100649,CG 100649

Target: COX, Carbonic Anhydrase

5'-Amino-5'-deoxyadenosine

T21017

Synonym: 5' Amino 5' deoxyadenosine,5'Amino5'deoxyadenosine,Nsc 238990,NH2dAdo

Target: Apoptosis, Adenosine Receptor

Glofitamab

T76685

Synonym: RO7082859,RG 6026,CD20-TCB

Target: Others

Tiragolumab

T35392

Synonym: RO 7092284,RG6058-10,MTIG-7192A,RG6058-11,RG-6058

Target: Others

1,4-Dideoxy-1,4-epithio-D-ribitol

TNU0839

Synonym:

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

2'-Deoxy-2'-fluoro-beta-D-arabinoguanosine

Synonym: IN-10018,BI-853520

Target: FAK

Pemetrexed disodium

T0189L

Synonym: LY-231514,LY231514 disodium,Pemetrexed

Target: Apoptosis, DHFR, DNA/RNA Synthesis, Antifolate, Autophagy

2'-O-Methyl-5-iodouridine

TNU0630

Synonym: 5-Iodo-2'-O-methyluridine

Target: Androgen Receptor

Synonym: BIM28131,RM 131,BIM-28131,BIM-28163,BIM 28163,BIM28163,BIM 28131

Target: Virus Protease, MNK, BTK

Isatuximab

T38951

Synonym: SAR-650984,hu38SB19,Isatuximab-irfc

Target: Apoptosis, CD38

Target: Nucleoside Antimetabolite/Analog

カタログ番号	製品名	別名	ターゲット
TN2069	Picrocrocin		Apoptosis
	Picrocrocin is a natural product		Apoptosis
T7548	1-Methylguanosine	N1-Methylguanosine	Endogenous Metabolite
	1-Methylguanosine (N1-Methylguanosine) is a methylated nucleoside. It is known that some modified, especially methylated, nucleosides originating from RNA degradation are excreted in abnormal levels in the urine of patie...		Endogenous Metabolite
T5814	Aurantiamide	TMC-58B	p38 MAPK , NF-κB
	Aurantiamide has anti-cancer, anti-inflammatory and antinociceptive activities, it may suppress the growth of malignant gliomas by blocking autophagic flux.Aurantiamide has an anti-neuroinflammatory effect on LPS stimula...		p38 MAPK , NF-κB
TN6733	Kansuiphorin C	KPC	Others
	Kansuiphorin C (KPC) is a natural product with a number of bioactivity. KPC could ameliorate malignant ascites by modulating gut microbiota mainly containing the increase of Lactobacillus and the decrease of Helicobacter...		Others
T5282	5-Methyluridine	Ribothymidine,Thymine riboside	Others , Endogenous Metabolite
	5-Methyluridine (Thymine riboside) is an endogenous methylated nucleoside found in human fluids; methylated purine bases are present in higher amounts in tumor-bearing patients compared to healthy controls.DNA hypermethy...		Others , Endogenous Metabolite
T5S0506	Rotundic acid	Rutundic acid	Apoptosis , Others , p38 MAPK , Akt , mTOR
	Rotundic acid (Rutundic acid), a natural compound, exhibit cytotoxic activities toward human hepatocellular carcinoma (HepG2), malignant melanoma (A375), SCLC (NCI-H446), breast cancer (MCF-7), and colon cancer (HT-29) c...		Apoptosis , Others , p38 MAPK , Akt , mTOR
T4928	L-Kynurenine	(S)-Kynurenine	AhR , Aryl Hydrocarbon Receptor , Endogenous Metabolite
	L-Kynurenine ((S)-Kynurenine) is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase, KMO, and KAT associated with the suppression of antitumor immune responses. It has ...		AhR , Aryl Hydrocarbon Receptor , Endogenous Metabolite
T5004	Hyaluronic acid sodium	Sodium Hyaluronate	Others
	Hyaluronic acid sodium (Sodium Hyaluronate) is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. It is unique among glycosaminoglycans in that it is nonsu...		Others
T4S0350	Licochalcone B		Beta Amyloid , Others
	1. Licochalcone B (LCB) inhibits the proliferation of human malignant bladder cancer cell lines (T24 and EJ) in vitro and antitumor activity in vivo in MB49 (murine bladder cancer cell line) tumor model. 2. LCB and Licoc...		Beta Amyloid , Others
TN1867	Licoricidin		MMP , VEGFR , ROS
	Licoricidin, is a potent anti-metastatic agent, which can markedly inhibit the metastatic and invasive capacity of malignant prostate cancer cells.		MMP , VEGFR , ROS
TN3931	Ent-11alpha-Hydroxy-15-oxokaur-16-en-19-oic acid		ERK , BCL , p38 MAPK , NF-κB , Caspase , JNK , p53
	Ent-11alpha-Hydroxy-15-oxokaur-16-en-19-oic acid has anti-cancer activity, it induces apoptosis of human malignant cancer cells, it also inhibits hepatocellular carcinoma in vitro and in vivo via stabilizing IkBα.		ERK , BCL , p38 MAPK , NF-κB , Caspase , JNK , p53
T79983	Flaccidoside II		Apoptosis
	Flaccidoside II, an active triterpenoid saponin from Anemone flaccida rhizome, both inhibits proliferation and induces apoptosis in Malignant Peripheral Nerve Sheath Tumors (MPNSTs) cell lines and ameliorates collagen-in...		Apoptosis
TN6685	Homovanillic Acid Sulfate
	Homovanillic acid sulfate is used as a reagent to detect oxidative enzymes, and is associated with dopamine levels in the brain.In psychiatry and neuroscience, brain and cerebrospinal fluid levels of homovanillic acid ar...

天然物製品

Synonym: N1-Methylguanosine

Target: Endogenous Metabolite

Aurantiamide

T5814

Synonym: TMC-58B

Target: p38 MAPK, NF-κB

Synonym: Ribothymidine,Thymine riboside

Target: Others, Endogenous Metabolite

Rotundic acid

T5S0506

Synonym: Rutundic acid

Target: Apoptosis, Others, p38 MAPK, Akt, mTOR

L-Kynurenine

T4928

Synonym: (S)-Kynurenine

Target: AhR, Aryl Hydrocarbon Receptor, Endogenous Metabolite

Hyaluronic acid sodium

T5004

Synonym: Sodium Hyaluronate

Target: Beta Amyloid, Others

Licoricidin

TN1867

Synonym:

Target: MMP, VEGFR, ROS

ent-11alpha-Hydroxy-15-oxokaur-16-en-19-oic acid

TN3931

Synonym:

Target: ERK, BCL, p38 MAPK, NF-κB, Caspase, JNK, p53

Homovanillic Acid Sulfate

TN6685

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-01442	DMBT1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB d...
TMPY-00021	PADI4 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Protein-arginine deiminase type-4, also known as HL-6 PAD, Peptidylarginine deiminase IV, Protein-arginine deiminase type I V and PADI4, is a cytoplasm and nucleus protein that belongs to the protein arginine deiminase f...
TMPY-04153	RNF43 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	RNF43 mutations are frequently detected in colorectal cancer cells and lead to a loss of function of the ubiquitin E3 ligase. The outer mitochondrial membrane 34 (TOMM34) and ring finger protein 43 (RNF43) as highly expr...
TMPY-01280	FOLR2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Folate receptor beta, also known as Folate receptor 2, FBP, and FOLR2, is a member of the folate receptor family. FOLR2 is expressed in placenta and hematopoietic cells. The expression of FOLR2 is increased in malignant ...
TMPY-00566	CCL18 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	CCL18 is a chemotactic cytokine involved in the pathogenesis and progression of various disorders, including cancer. Proof showed high levels of CCL18 in the serum of epithelial ovarian carcinoma patients suggesting its...
TMPK-01441	HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumor...
TMPK-01447	HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumor...
TMPK-01454	HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumor...
TMPK-01455	HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumor...
TMPK-01406	HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled	Human	HEK293 Cells
	PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumor...
TMPJ-01145	ABCB5 Protein, Human, Recombinant (Trx)	Human	E. coli
	ATP-binding cassette sub-family B member 5(ABCB5) is a plasma membrane-spanning protein. ABCB5 is principally expressed in physiological skin and human malignant melanoma. ABCB5 has been suggested to regulate skin progen...
TMPY-01346	Psoriasin/S100A7 Protein, Human, Recombinant	Human	E. coli
	Protein S100-A7, also known as S100 calcium-binding protein A7, Psoriasin, S100A7, and PSOR1, is a secreted protein which belongs to theS-100 family. S100A7 was first isolated from skin involved by psoriasis, which can b...
TMPY-02399	TRF1 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Telomeric repeat binding factor 1 (TRF1), also known as TERF1, the shelterin complex, which modulates the telomere structures. TRF1 protein structure contains a C-terminal Myb motif, a dimerization domain near its N-term...
TMPJ-01137	MIA Protein, Human, Recombinant (His)	Human	E. coli
	Melanoma Inhibitory Activity Protein (MIA) is an autocrine growth regulatory protein secreted from chondrocytes and malignant melanoma cells, which was the first discovered member of a family of secreted cytokines termed...
TMPK-01381	CSPG4/MCSP Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	The chondroitin sulfate proteoglycan-4 (CSPG4) is a cell surface proteoglycan overexpressed in a huge range of human and canine neoplastic lesions by tumor cells, tumor microenvironment and cancer initiating cells. CSPG4...
TMPK-01467	HLA-A*02:01&B2M&HPV 16 E6 (KLPQLCTEL) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Human papillomavirus (HPV) 16 infection is a necessary condition for the pathogenesis and development of cervical cancer. The E6 protein is expressed by the HPV16 E6 gene and promotes malignant phenotype transformation, ...
TMPK-01466	HLA-A*02:01&B2M&HPV 16 E6 (KLPQLCTEL) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Human papillomavirus (HPV) 16 infection is a necessary condition for the pathogenesis and development of cervical cancer. The E6 protein is expressed by the HPV16 E6 gene and promotes malignant phenotype transformation, ...
TMPY-05160	PFKP Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	PFKP plays a critical role in cell proliferation in breast cancer cells. PFKP is necessary for starvation-mediated autophagy, glycolysis, and EMT, thereby promoting the malignant progression of OSCC. The Snail-PFKP axis ...
TMPK-01051	BLOC1S2 Protein, Human, Recombinant	Human	E. coli
	BLOC1S2 (Biogenesis of lysosome-related organelles complex-1 subunit 2) protein is widely expressed in normal tissue as well as in malignant tumors with a tendency towards lower expression levels in certain subtypes of t...
TMPK-00618	FcRH5/FcRL5 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE),...
TMPY-01299	GMF gamma/GMFG Protein, Human, Recombinant (His)	Human	E. coli
	The glia maturation factor gamma (GMFG) is a cytokine-responsive protein in erythropoietin-induced and granulocyte-colony stimulating factor-induced hematopoietic lineage development. It may mediate the pluripotentiality...
TMPK-01145	FcRH5/FcRL5 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE),...
TMPY-02712	Serpin B3 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	SERPINB3, also known as SCCA-1, belongs to the serpin family. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was orig...
TMPK-01282	FAP Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated	Cynomolgus	HEK293 Cells
	Fibroblast activation protein (FAP) is a serine protease that has been reported in fibroblasts and some carcinoma cells, which correlates with poor patient outcomes. FAP can be induced under hypoxia which is also vital i...
TMPK-00619	FcRH5/FcRL5 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
	FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE),...
TMPK-00373	FAP Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Fibroblast activation protein (FAP) is a serine protease that has been reported in fibroblasts and some carcinoma cells, which correlates with poor patient outcomes. FAP can be induced under hypoxia which is also vital i...
TMPK-00234	CD84 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Chronic lymphocytic leukemia (CLL) is characterized by the accumulation of CD5 B lymphocytes in peripheral blood, lymphoid organs and bone marrow. The main feature of the disease is accumulation of the malignant cells du...
TMPK-00923	FAP Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Fibroblast activation protein (FAP) is a serine protease that has been reported in fibroblasts and some carcinoma cells, which correlates with poor patient outcomes. FAP can be induced under hypoxia which is also vital i...
TMPK-01039	FcRH5/FcRL5 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE),...
TMPY-02497	S100A15 Protein, Mouse, Recombinant (His & MBP)	Mouse	E. coli
	Koebnerisin is also known as protein S100-A7A (S100A7A), S100 calcium-binding protein A7-like 1 (S100A7L1) or S100 calcium-binding protein A15 (S100A15). Human S100A7A / S100A15 is a novel member of the S100 family of EF...
TMPK-00732	WISP1/CCN4 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	The interplay between glioma stem cells (GSCs) and the tumor microenvironment plays crucial roles in promoting malignant growth of glioblastoma (GBM), the most lethal brain tumor. WISP1 is preferentially expressed and se...
TMPY-04149	RNF43 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	RNF43 mutations are frequently detected in colorectal cancer cells and lead to a loss of function of the ubiquitin E3 ligase. The outer mitochondrial membrane 34 (TOMM34) and ring finger protein 43 (RNF43) as highly expr...
TMPY-00481	AKR1C4 Protein, Human, Recombinant (His)	Human	E. coli
	Aldo-keto reductases comprise of AKR1C1-AKR1C4, four enzymes that catalyze NADPH dependent reductions and have been implicated in biosynthesis, intermediary metabolism, and detoxification. there is a strong correlation ...
TMPK-00992	SEZ6L2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Seizure-related 6 homolog (mouse)-like 2 (SEZ6L2) was shown to be involved in transcription of a type 1 transmembrane protein for regulating cell fate. SEZ6L2 was significantly up-regulated in tumour tissues of patients ...
TMPK-01502	HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel...
TMPK-01542	HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel...
TMPK-01503	HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel...
TMPK-01534	Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human&Mouse, MHC (His & Avi)	Human & Mouse	HEK293 Cells
	The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel...
TMPK-01530	HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel...
TMPK-01498	HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel...
TMPK-01535	Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human&Mouse, MHC (His & Avi)	Human & Mouse	HEK293 Cells
	The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel...
TMPK-01083	ASPH Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Aspartate β-hydroxylase (ASPH) is silent in normal adult tissues only to re-emerge during oncogenesis where its function is required for generation and maintenance of malignant phenotypes. Exosomes enable prooncogenic se...
TMPK-00945	ASPH Protein, Human, Recombinant (His)	Human	E. coli
	Aspartate β-hydroxylase (ASPH) is silent in normal adult tissues only to re-emerge during oncogenesis where its function is required for generation and maintenance of malignant phenotypes. Exosomes enable prooncogenic se...
TMPK-01533	HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel...
TMPK-00931	CD164 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	CD164 was found to play a role in many malignant diseases. CD164 was associated with clinical and pathological features of patients. High level of CD164 was related to the distant metastasis and vascular invasion of blad...
TMPK-01220	CD164 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	CD164 was found to play a role in many malignant diseases. CD164 was associated with clinical and pathological features of patients. High level of CD164 was related to the distant metastasis and vascular invasion of blad...
TMPJ-00524	SORD Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Sorbitol dehydrogenase, also known as L-iditol 2-dehydrogenase and SORD, is a member of the zinc-containing alcohol dehydrogenase family. SORD exsits in a homotetramer and binds one zinc ion per subunit. SORD is expresse...
TMPJ-00159	EMMPRIN/CD147 Protein, Human, Recombinant (Avi & His), Biotinylated	Human	HEK293 Cells
	Basigin/CD147 is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermato...
TMPY-03117	Zinc Alpha 2 Glycoprotein/AZGP1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Alpha-2-glycoprotein, also known as AZGP1, belongs to the MHC class I family. It can be detected in body fluids such as serum, sweat, and seminal and breast cyst fluids. It has been shown that alpha-2-glycoprotein can st...
TMPJ-00352	CD98 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	CD98 is a multifunctional glycoprotein that is involved in various biological processes such as amino acid transport, cell adhesion, diffusion, adhesion, and proliferation. CD98 can interact with CD147 to induce integrin...
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DMBT1 Protein, Human, Recombinant (His)

TMPY-01442

Species: Human

Expression System: HEK293 Cells

PADI4 Protein, Human, Recombinant (His)

TMPY-00021

Species: Human

Expression System: Baculovirus Insect Cells

RNF43 Protein, Human, Recombinant (His)

TMPY-04153

Species: Human

Expression System: HEK293 Cells

FOLR2 Protein, Human, Recombinant (His)

TMPY-01280

Species: Human

Expression System: HEK293 Cells

CCL18 Protein, Human, Recombinant (His)

TMPY-00566

Species: Human

Expression System: P. pastoris (Yeast)

HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Monomer Protein, Human, MHC (His & Avi)

TMPK-01441

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Monomer Protein, Human, MHC (His & Avi), Biotinylated

TMPK-01447

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Tetramer Protein, Human, MHC (His & Avi)

TMPK-01454

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Monomer Protein, Human, MHC (His & Avi)

TMPK-01455

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled

TMPK-01406

Species: Human

Expression System: HEK293 Cells

ABCB5 Protein, Human, Recombinant (Trx)

TMPJ-01145

Species: Human

Expression System: E. coli

Psoriasin/S100A7 Protein, Human, Recombinant

TMPY-01346

Species: Human

Expression System: E. coli

TRF1 Protein, Human, Recombinant (His)

TMPY-02399

Species: Human

Expression System: Baculovirus Insect Cells

MIA Protein, Human, Recombinant (His)

TMPJ-01137

Species: Human

Expression System: E. coli

CSPG4/MCSP Protein, Cynomolgus, Recombinant (His)

TMPK-01381

Species: Cynomolgus

Expression System: HEK293 Cells

HLA-A*02:01&B2M&HPV 16 E6 (KLPQLCTEL) Monomer Protein, Human, MHC (His & Avi)

TMPK-01467

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&HPV 16 E6 (KLPQLCTEL) Tetramer Protein, Human, MHC (His & Avi)

TMPK-01466

Species: Human

Expression System: HEK293 Cells

PFKP Protein, Human, Recombinant (His & GST)

TMPY-05160

Species: Human

Expression System: Baculovirus Insect Cells

BLOC1S2 Protein, Human, Recombinant

TMPK-01051

Species: Human

Expression System: E. coli

FcRH5/FcRL5 Protein, Human, Recombinant (His)

TMPK-00618

Species: Human

Expression System: HEK293 Cells

GMF gamma/GMFG Protein, Human, Recombinant (His)

TMPY-01299

Species: Human

Expression System: E. coli

FcRH5/FcRL5 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-01145

Species: Human

Expression System: HEK293 Cells

Serpin B3 Protein, Human, Recombinant (His)

TMPY-02712

Species: Human

Expression System: Baculovirus Insect Cells

FAP Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated

TMPK-01282

Species: Cynomolgus

Expression System: HEK293 Cells

FcRH5/FcRL5 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated

TMPK-00619

Species: Human

Expression System: HEK293 Cells

FAP Protein, Human, Recombinant (hFc)

TMPK-00373

Species: Human

Expression System: HEK293 Cells

CD84 Protein, Human, Recombinant (His & Avi)

TMPK-00234

Species: Human

Expression System: HEK293 Cells

FAP Protein, Mouse, Recombinant (His)

TMPK-00923

Species: Mouse

Expression System: HEK293 Cells

FcRH5/FcRL5 Protein, Mouse, Recombinant (His)

TMPK-01039

Species: Mouse

Expression System: HEK293 Cells

S100A15 Protein, Mouse, Recombinant (His & MBP)

TMPY-02497

Species: Mouse

Expression System: E. coli

WISP1/CCN4 Protein, Mouse, Recombinant (His)

TMPK-00732

Species: Mouse

Expression System: HEK293 Cells

RNF43 Protein, Human, Recombinant (hFc)

TMPY-04149

Species: Human

Expression System: HEK293 Cells

AKR1C4 Protein, Human, Recombinant (His)

TMPY-00481

Species: Human

Expression System: E. coli

SEZ6L2 Protein, Mouse, Recombinant (His)

TMPK-00992

Species: Mouse

Expression System: HEK293 Cells

HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Monomer Protein, Human, MHC (His & Avi), Biotinylated

TMPK-01502

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human, MHC (His & Avi)

TMPK-01542

Species: Human

Expression System: HEK293 Cells

HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Monomer Protein, Human, MHC (His & Avi)

TMPK-01503

Species: Human

Expression System: HEK293 Cells

Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human&Mouse, MHC (His & Avi)

TMPK-01534

Species: Human & Mouse

Expression System: HEK293 Cells

HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human, MHC (His & Avi), Biotinylated

TMPK-01530

Species: Human

Expression System: HEK293 Cells

HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Tetramer Protein, Human, MHC (His & Avi)

TMPK-01498

Species: Human

Expression System: HEK293 Cells

Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human&Mouse, MHC (His & Avi)

TMPK-01535

Species: Human & Mouse

Expression System: HEK293 Cells

ASPH Protein, Mouse, Recombinant (His)

TMPK-01083

Species: Mouse

Expression System: E. coli

ASPH Protein, Human, Recombinant (His)

TMPK-00945

Species: Human

Expression System: E. coli

HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human, MHC (His & Avi)

TMPK-01533

Species: Human

Expression System: HEK293 Cells

CD164 Protein, Human, Recombinant (hFc)

TMPK-00931

Species: Human

Expression System: HEK293 Cells

CD164 Protein, Mouse, Recombinant (hFc)

TMPK-01220

Species: Mouse

Expression System: HEK293 Cells

SORD Protein, Human, Recombinant (His)

TMPJ-00524

Species: Human

Expression System: HEK293 Cells

EMMPRIN/CD147 Protein, Human, Recombinant (Avi & His), Biotinylated

TMPJ-00159

Species: Human

Expression System: HEK293 Cells

Zinc Alpha 2 Glycoprotein/AZGP1 Protein, Human, Recombinant (His)

TMPY-03117

Species: Human

Expression System: HEK293 Cells

CD98 Protein, Human, Recombinant (mFc)

TMPJ-00352

Species: Human

Expression System: HEK293 Cells

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カタログ番号	製品名
L2152	Targeted Therapy Drug Library	119 compounds
	119 tumor-targeted drugs that can be used for high-throughput and high-content screening.
L2196	Anti-Ovarian Cancer Compound Library	1867 compounds

L2500	Human Endogenous Metabolite Library	499 compounds
	A collection of 499 selected human endogenous metabolites for high throughput and high content screening.
L9410	Covalent Inhibitor Library	1920 compounds
	A unique collection of 1920 covalent Inhibitors and other molecules with common warheads like chloroacetyl，2-Chloropropionyl，Acryloyl，sulfonyl fluoride, alkyne，acrylamide, ketocarbonyl，disulfide bond, etc.

ライブラリー

Targeted Therapy Drug Library

L2152

Compounds: 119

Anti-Ovarian Cancer Compound Library

L2196

Compounds: 1867

Human Endogenous Metabolite Library

L2500

Compounds: 499

Covalent Inhibitor Library

L9410

Compounds: 1920