1252
891
37
16
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T64358 | Anti-inflammatory agent 35 | Immunology/Inflammation related | |
Anti-inflammatory agent 35 is a potent anti-inflammatory agent. | |||
T9748 | Anti-inflammatory agent 34 | Immunology/Inflammation related | |
Anti-inflammatory agent 34 shows moderate acute anti-inflammatory activity and analgesic activity in vivo. | |||
T64359 | Anti-inflammatory agent 36 | Immunology/Inflammation related | |
Anti-inflammatory agent 36 is an anti-inflammatory agent. It exhibited dose-dependent inhibition of LPS-induced release of TNF-a and IL-6 in active RAW 264.7 mouse macrophages, IC50=3.69uM and 3.68uM, respectively. | |||
T21606L | Anti-Inflammatory Peptide 1 Acetate | Anti-Inflammatory Peptide 1 Acetate(118850-70-8 Free base) | Phospholipase |
Anti-Inflammatory Peptide 1 Acetate (C45H82N12O14S2) possesses a potent anti-inflammatory activity in vivo and is a strong inhibitor of phospholipase A2 (PLA2), whose increased presence and activity results in inflammati... | |||
T77582 | Anti-inflammatory agent 51 | NF-κB | |
Anti-inflammatory agent 51 is an amide/sulfonamide derivative with anti-inflammatory and potentially anti-tumor activity and inhibition of NF-κB activation, which can be used to study acute lung injury and ulcerative col... | |||
T75174 | Anti-inflammatory agent 42 | IL Receptor , TNF | |
Anti-inflammatory agent 42 has anti-inflammatory activity and inhibits the expression of TNF-α and IL-6 in LPS-stimulated macrophages. | |||
T10091 | Anti-inflammatory agent 1 | Others | |
Anti-inflammatory agent 1 is an anti-inflammatory compound. | |||
T10917 | LTB4-IN-1 | Anti-inflammatory agent 2 | LTR |
LTB4-IN-1 (Anti-inflammatory agent 2) with IC50 of 70 nM is an inhibitor of leukotriene synthesis (LTB4). | |||
T9582 | CLEFMA | NF-κB | |
CLEFMA has anti-proliferative activity. CLEFMA inhibits tumor growth associated with NF-κB-regulated anti-inflammatory and anti-metastatic effects. | |||
T50025 | Lonazolac | PPAR | |
Lonazolac is a nonsteroidal anti-inflammatory drug[1]. | |||
T7969 | Dipyrithione | Others | |
Dipyrithione appears to have novel cytotoxicity and potent broad-spectrum antitumor activity | |||
TP1466 | Z-YVAD-FMK | Caspase | |
AA-Z-YVAD-FMK is a Irreversible caspase-1 inhibitor,with anti-inflammatory and anti-tumor activities. | |||
T60670 | Anti-inflammatory agent 14 | ||
Anti-inflammatory agent 14 (compound 28) has a MIC 50 of 2 μM for Mtb H37Rv. Anti-inflammatory agent 14 is also an anti-inflammatory agent [1]. | |||
T63660 | Anti-inflammatory agent 19 | ||
Anti-inflammatory agent 19 inhibits NO (IC50: 36.00 μM). anti-inflammatory agent 19 exhibits an inhibitory effect on HMGB1-induced late inflammatory responses. anti-inflammatory agent 19 can be used to study late inflamm... | |||
T61302 | Anti-inflammatory agent 17 | ||
Anti-inflammatory agent 17 an orally active anti-inflammatory agent, demonstrates potent efficacy in inhibiting the release of IL-6 and TNF-α without causing cytotoxicity in in vitro experiments. Furthermore, in vivo stu... | |||
T60560 | Anti-inflammatory agent 15 | ||
Anti-inflammatory agent 15 (compound 29) is a potent antimycobacterial agent that can be used in the research of tuberculosis (TB). Anti-inflammatory agent 15 inhibits the growth of Mtb H37Rv and M299 with MIC50 of 2.3 a... | |||
T60570 | Anti-inflammatory agent 11 | ||
Anti-inflammatory agent 11 (compound 16) is a potent antimycobacterial agent that can be used in the research of tuberculosis(TB). Anti-inflammatory agent 11 inhibits the growth of Mtb H37Rv and M299 with MIC 50 of 1.3 a... | |||
T74895 | Anti-inflammatory agent 31 | ||
Anti-inflammatory agent 31 (enone 17), an andrographolide derivative, acts as an anti-inflammatory agent by inhibiting NF-κB activation through the upstream blockade of PI3K/Akt and ERK1/2 MAPK pathways. It effectively r... | |||
T61548 | Anti-inflammatory agent 22 | ||
Anti-inflammatory agent 22 (compound 14a) is a potent orally active compound with anti-inflammatory properties. It effectively inhibits the production of TNF-α induced by LPS, exhibiting an IC50 value of 14.6 μM. Additio... | |||
T72202 | Anti-inflammatory agent 33 | ||
Anti-inflammatory agent 33, a potent p38α inhibitor, effectively reduces NO production and suppresses LPS-induced expression of iNOS, COX-2, p-p38α, and p-MK2 proteins, thereby demonstrating anti-inflammatory activity. | |||
T79599 | Anti-inflammatory agent 53 | COX | |
Anti-inflammatory agent 52 (compound 7c) is an orally active, selective COX-2 inhibitor with demonstrated anti-HT29 metastatic activity, causing periodic arrest in the S phase and G2/M phase. This agent exhibits moderate... | |||
T79670 | Anti-inflammatory agent 56 | COX | |
Anti-inflammatory agent 56 (Compound 9), a selective COX-2 inhibitor with an IC50 of 0.54 μM, exhibits anti-oxidant and anti-inflammatory properties by inhibiting oxidative stress-induced cell death and neuroinflammation... | |||
T83053 | Anti-inflammatory agent 59 | ||
Anti-inflammatory agent 58 is characterized by its ability to inhibit IL-1β with an IC50 value of 2.28 μM. Furthermore, it reduces pro-inflammatory gene expression, protein secretion, and NF-κB phosphorylation [1]. | |||
T83047 | Anti-inflammatory agent 65 | STING | |
Anti-inflammatory agent 65 (compound 29), a Hederagonic acid derivative, exhibits potent activity by inhibiting nitric oxide (NO) release, nuclear translocation of IRF3 and p65, and disrupting the STING/IRF3/NF-κB signal... | |||
T79585 | Anti-inflammatory agent 50 | NF-κB | |
Anti-inflammatory agent 50 (compound a1), a derivative of Fusidic acid, exerts its effects through inhibition of inflammatory mediators including NO, IL-6, and TNF-α. It mitigates acute lung injury by modulating these me... | |||
T79473 | Anti-inflammatory agent 46 | NO Synthase | |
Anti-inflammatory agent 46 (compound 7h), exhibiting nitric oxide (NO) inhibitory properties, demonstrates a high affinity for iNOS through low binding energies and effectively reduces swelling in mouse models at a dose ... | |||
T62284 | Anti-inflammatory agent 21 | ||
Anti-inflammatory agent 21 (compound 9o) is a low cytotoxic, orally active anti-inflammatory agent that acts on NO (IC50: 0.76 μM). Anti-inflammatory agent 21 is able to accumulate ROS and block NF-κB/MAPK signaling path... | |||
T62967 | Anti-inflammatory agent 10 | ||
Anti-inflammatory agent 10 is a tilomisole-based benzimidazole-thiazole derivative that is orally active. anti-inflammatory agent 10 is more active against COX-2 enzymes than COX-1. | |||
T79507 | Anti-inflammatory agent 48 | NF-κB | |
Anti-inflammatory agent 48 functions by inhibiting the NF-κB signaling pathway and activating HO-1 expression, characterizing its role as an anti-inflammatory agent [1]. | |||
T63061 | Anti-inflammatory agent 13 | ||
Anti-inflammatory agent 13 is a pentacyclic triterpene compound with a significant inhibitory effect on inflammation models. anti-inflammatory agent 13 has the potential to be used in studies of DAMP or PAMP-induced infl... | |||
T83058 | Anti-inflammatory agent 44 | ||
Compound 1 (Anti-inflammatory agent 44) is a 6-methoxyflavonol glycoside exhibiting anti-inflammatory properties, and it can be extracted from the aerial parts of Tetragonia tetragonoides [1]. | |||
T83050 | Anti-inflammatory agent 62 | ||
Anti-inflammatory agent 62 mitigates acetaminophen-induced hepatotoxicity in HepG2 cells by modulating inflammatory and oxidative stress pathways [1]. | |||
T63107 | Anti-inflammatory agent 6 | ||
Anti-inflammatory agent 6 exhibits anti-inflammatory potential by blocking the phosphorylation of Iκb kinase α/β (IKKα/β), IκBα and nuclear factor kB p65 (NF-κb p65), which are key controllers of inflammation. | |||
T83051 | Anti-inflammatory agent 61 | ||
Compound 5b (Anti-inflammatory agent 61) is a potent anti-inflammatory agent that diminishes TNF-α expression in LPS-induced inflammation within RAW 264.7 cells and mitigates APAP-induced inflammation in HepG2 cells [1]. | |||
T83048 | Anti-inflammatory agent 64 | ROS Kinase | |
Anti-inflammatory agent 64 (compound 4b) exhibits antioxidant and anti-inflammatory activities, effectively inhibiting the secretion of IL-6 and TNF-α while also reducing paw edema [1] in both in vitro and in vivo studie... | |||
T72223 | Anti-inflammatory agent 7 | ||
Anti-inflammatory Agent 7 suppresses proinflammatory cytokines by hindering the NF-κB/MAPK signaling pathway in both LPS-treated RAW 264.7 cells and mice. | |||
T79598 | Anti-inflammatory agent 52 | COX | |
Anti-inflammatory agent 52 (compound 7j) is an orally active, selective COX-2 inhibitor with the capability to induce G2/M phase arrest and exhibit anti-HT29 transfer activity. It demonstrates moderate anti-inflammatory ... | |||
T79619 | Anti-inflammatory agent 54 | ||
Anti-inflammatory agent 54 (compound 9c), a Coixol derivative, exhibits anti-inflammatory properties by inhibiting the NF-κB pathway and reducing the expression of pro-inflammatory cytokines such as iNOS, TNF-α, IL-6, an... | |||
T83052 | Anti-inflammatory agent 60 | NF-κB | |
Anti-inflammatory agent 60 (compound 21) inhibits nitric oxide production, presenting an IC50 of 12.95 μM, and reduces iNOS, phosphorylated p65, and β-catenin expression in a concentration-dependent manner [1]. | |||
T83057 | Anti-inflammatory agent 49 | ||
Compound SC9, an anti-inflammatory agent, serves as a potent and selective inhibitor of the Drp1-Fis1 interaction, mitigating FIS1-mediated mitochondrial dysfunction. It exhibits an in vitro IC50 value of 270 nM for inhi... | |||
T79480 | Anti-inflammatory agent 47 | Reactive Oxygen Species | |
Flo8, an anti-inflammatory and antioxidant agent, effectively suppresses the release of reactive oxygen species (ROS) and nitric oxide (NO) while inhibiting neuronal apoptosis by modulating inflammatory and apoptotic sig... | |||
T79478 | Anti-inflammatory agent 45 | Apoptosis | |
Compound 2v (Anti-inflammatory agent 45) demonstrates anticancer properties with direct inhibitory impacts on the proliferation of various blood malignancies, such as leukemia, lymphoma, and myeloma cell lines. It induce... | |||
T64018 | Anti-inflammatory agent 23 | ||
Anti-inflammatory agent 23 is an anti-inflammatory agent that inhibits LPS-activated NO production (IC50: 0.449 μM). anti-inflammatory agent 23 exhibits good affinity for p65 protein. | |||
T78967 | Anti-inflammatory agent 40 | Parasite | |
Anti-inflammatory agent 40 is a promising, orally-active compound with anti-malarial and anti-inflammatory properties. It effectively inhibits carrageenan-induced paw swelling in vivo. | |||
T61637 | Anti-inflammatory agent 8 | ||
Anti-inflammatory agent 8 (compound 13) designated as an anti-inflammatory agent 8, displays enhanced activity on the COX-2 enzyme compared to COX-1, with an IC50 value of 0.09 nM. Furthermore, anti-inflammatory agent 8 ... | |||
T61400 | Anti-inflammatory agent 9 | ||
Anti-inflammatory agent 9 (compound 28)Anti-inflammatory agent 9 (compound 28) is a benzimidazothiazole derivative derived from tilomisole. It exhibits a higher affinity for the COX-2 enzyme compared to COX-1, thereby de... | |||
T63092 | Anti-inflammatory agent 12 | ||
Anti-inflammatory agent 12 is a pentacyclic triterpene compound that showed a significant bias in LPS-induced inflammatory responses (IC50: 2.22 μM). anti-inflammatory agent 12 has potential for use in inflammatory disea... | |||
T61810 | Anti-inflammatory agent 16 | ||
Anti-inflammatory agent 16 (compound 14) is a highly effective peptidomimetic with potent anti-inflammatory properties. It effectively reduces the expression levels of TNFα, NO, CD40, and CD86 [1]. | |||
T79620 | Anti-inflammatory agent 55 | ||
Compound 9j (anti-inflammatory agent 55), a Coixol derivative, exhibits anti-inflammatory properties by inhibiting the NF-κB pathway and reducing the expression of iNOS, TNF-α, IL-6, and IL-1β. It notably suppresses LPS-... | |||
T74540 | Anti-inflammatory agent 38 | ||
Anti-inflammatory agent 38 (compound 23d) is a potent Nrf2/HO-1 pathway inhibitor, with an IC 50 value of 0.38 μM for NO . Nrf2/HO-1-IN-1 can significantly reduce the level of ROS in cells. Nrf2/HO-1-IN-1 can be used for... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T4S1849 | Tubeimoside III | Others | |
Tubeimoside III has anti-inflammatory, anti-tumor, and anti-tumorigenic activities, stronger than those of tubeimoside II. | |||
TN2151 | Rhamnocitrin | Others | |
Rhamnocitrin can enhance the immune function, improve the formation of spleen cells of mice serum hemolysin of chicken red blood cell immune. | |||
TN7020 | Astragenol | Others | |
Astragenol is an intermediate for the synthesis of astragenel derivatives. Astragenol derivatives are promising anti-inflammatory drugs in prostate cancer research. | |||
T5660 | Menthone | IL Receptor , TNF , NF-κB , Parasite | |
Menthone has anti-inflammary activity,, it can suppress the lipopolysaccharide (LPS)-induced proinflammatory cytokines, interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha (TNF-alpha),as well as nuclear factor k... | |||
TN2085 | Piperlonguminine | Anti-infection , Antibacterial , Antifungal | |
Piperlonguminine is an alkaloid amide isolated from the Piper species. Piperlonguminine shows anti-inflammatory, antitumor, neuroprotective, anti-platelet, anti-melanogenic, antifungal and antibacterial activities.Piperl... | |||
T8030 | Ethyl pyruvate | Apoptosis , Antioxidant | |
Ethyl pyruvate is a simple aliphatic ester of pyruvic acid and has been shown to have robust neuroprotective effects via its anti-inflammatory, anti-oxidative, and anti-apoptotic functions. | |||
TN6490 | Regaloside C | Others | |
Regaloside C is a glycerol glucoside isolated from Lilium genus with anti-inflammatory properties. | |||
T6S0139 | Neobavaisoflavone | Apoptosis , DNA/RNA Synthesis | |
1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can si... | |||
T4S0590 | Columbin | Phospholipase , COX , Parasite | |
1. Columbin has anti-inflammatory activity. 2. Columbin has chemopreventive ability against human colon cancer. 3. Columbin inhibits PLA2 hydrolysis of ghost RBC in a dose-dependent fashion. | |||
T7930 | Linalyl Acetate | Others | |
Linalyl Acetate is a natural product | |||
TN5888 | Toddaculin | Others | |
Toddaculine may be beneficial for the prevention and treatment of osteoporosis, it can not only inhibit the differentiation of osteoclasts via activation of the NF-κB, ERK 1/2, and p38 MAPK signaling pathways, but can in... | |||
T11366 | Garcinol | Apoptosis , Endogenous Metabolite , Histone Acetyltransferase , AChR , AChE | |
T5778 | 5,7-DIMETHOXYFLAVONE | Anti-infection , P450 | |
5,7-DIMETHOXYFLAVONE possessed remarkable leishmanicidal potential. | |||
TN2082 | Pinostrobin | Beta Amyloid , IL Receptor , Serine/threonin kinase , TNF | |
Pinostrobin, a potent flavonoid inducer, exerts a neuroprotective effect against Aα²(25-35)-induced neurotoxicity in PC12 cells, at least in part, via inhibiting oxidative damage and calcium overload, as well as suppress... | |||
T83062 | Anti-inflammatory agent 28 | ||
Compound 28 (Compound 9) is an anti-inflammatory agent with hepatoprotective activity [1]. | |||
T9862 | Pseudocoptisine chloride | Isocoptisine chloride | AChE |
Pseudocoptisine chloride (Isocoptisine chloride) is isolated from Corydalis Tuber with anti-inflammatory and anti-amnestic properties. Pseudocoptisine chloride inhibits acetylcholinesterase (AChE) activity (IC50 = 12.8 μ... | |||
T83060 | Anti-inflammatory agent 30 | ||
Compound 5 (Anti-inflammatory agent 30) exhibits anti-inflammatory properties and demonstrates hepatoprotective activity [1]. | |||
T83061 | Anti-inflammatory agent 29 | ||
Compound 29 (Compound 7) is an anti-inflammatory agent that exhibits hepatoprotective activity [1]. | |||
T83055 | Anti-inflammatory agent 57 | ||
Compound 13, also known as Anti-inflammatory agent 57 and classified as a pyranocoumarin, is a natural product extracted from the roots of Peucedanum praeruptorum. This compound possesses both multidrug-resistance (MDR) ... | |||
T83056 | Anti-inflammatory agent 5 | ||
Anti-inflammatory agent 5 effectively inhibits nitric oxide (NO) production in lipopolysaccharide-induced BV-2 microglial cells. | |||
T5S0691 | Shionone | Shionon | Others |
1. Shionone (Shionon) has anti-tussive and anti-inflammatory effects. | |||
T4S1718 | Punicalin | HBV , HIV Protease | |
Punicalin exerts anti-inflammatory, antioxidative, and anti-hepatotoxic activities, it shows inhibitory activity on HIV-1 reverse transcriptase in a dose-dependent manner, with an IC50 of 0.11 microg/ml (0.14 microM). | |||
T3S0509 | Gaultherin | COX | |
Gaultherin has analgesic, and anti-inflammatory activities.Gaultherin lacks gastric ulcerogenic effect, because of it released salicylate in intestine slowly, not in stomach and it left the cyclooxygenase-1 unaffected, w... | |||
T3866 | Macelignan | Anwuligan,(+)-Anwulignan | Others , COX |
Macelignan (Anwuligan) is a lignan isolated from nutmeg with antimicrobial and anticariogenic activity against Streptococcus mutans and other streptococcus species. | |||
T5712 | Zerumbone | Antioxidant , HSV | |
Zerumbone is a natural monocyclic sesquiterpene first isolated from rhizomes of the wild ginger Z. zerumbet.It has also been shown to have anti-oxidant and anti-inflammatory activities, contributing to immunomodulatory a... | |||
TN6729 | Azadiradione | AZD | Others |
Azadiradione (AZD) (AZD) from the methanolic extract of seeds of Azadirachta indica | |||
T4S2126 | Ginkgetin | Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy | |
1. Ginkgetin has anti-influenza virus and anti-fungal activities. 2. Ginkgetin has anti-inflammatory activity, can down-regulates COX-2 induction in vivo against skin inflammatory responses. 3. Ginkgetin is a good STAT3 ... | |||
T6S1435 | Notopterol | Apoptosis , Others | |
1. Notopterol induces apoptosis and inhibits cell cycle-specific. | |||
T3773 | Oxypaeoniflorin | Oxypaeoniflora | Others |
Oxypaeoniflorin (Oxypaeoniflora) is a natural product derived from Radix Paeoniae Rubra and Radix Paeoniae Alba. | |||
T6S1027 | Tussilagone | Others | |
1. Tussilagone inhibits dendritic cell function through the induction of heme oxygenase-1. 2. Tussilagone has anti-cancer activity, might be a potential chemotherapeutic agent for the prevention and treatment of human co... | |||
T2982 | Xanthone | Genicide,Xanthenone,Benzophenone oxide | Apoptosis , Others , Influenza Virus , Antibacterial , Antifungal |
Xanthone (Xanthenone) is currently used as ovicide for codling moth eggs and as a larvicide. | |||
TN3690 | Comanthoside B | Comanthosid B | Antibacterial |
Comanthoside B (Comanthosid B) is a natural product isolated from the aerial portions of Ruellia tuberosa L with anti-inflammatory and antiseptic activities. | |||
T2780 | Catalpol | Catalpinoside,Digitalis purpurea L | Others , HBV |
Catalpol (Catalpinoside) is an iridoid glycoside with neuroprotective, anti-inflammatory, and anti-hepatitis virus effects. | |||
TN1990 | Norathyriol | Akt , DNA/RNA Synthesis , AMPK , PPAR | |
Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability. | |||
T2S1200 | Sinapine | Antioxidant , P-gp , AChE | |
1. Sinapine, an alkaloid from seeds of the cruciferous species, can be used as an effective natural compound for chemo-resistance. 2. Sinapine has antioxidant and radio-protective activities. | |||
T4S1943 | Kirenol | Kirel | Wnt/beta-catenin |
1. Kirenol (Kirel) has anti-oxidant, anti-inflammatory, anti-allergic, and anti-arthritic activities. 2. Kirenol is effective against gram-positive bacteria. 3. Kirenol possesses antitumor action on human chronic myeloid... | |||
TN2331 | Eleutheroside B1 | Influenza Virus | |
Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits l... | |||
T4518 | Licochalcone D | ERK , NF-κB | |
Licochalcone D may be a potential drug for human melanoma treatment by inhibiting proliferation, inducing apoptosis via the mitochondrial pathway and blocking cell migration and invasion. Licochalcone D has cardioprotect... | |||
TN2239 | Strictosamide | ATPase , Potassium Channel , Sodium Channel , Parasite , Antifungal | |
Strictosamide possesses antibacterial and antiviral activities, it also may have important effects on inflammation and inflammatory pain. | |||
TN1493 | Chrysosplenol D | IL Receptor , NF-κB , JNK | |
Chrysosplenol D, an efflux pump inhibitor that can potentiate the activity of commercially important antibiotics and antimalarials. | |||
TN1721 | Gypenoside L | ERK , p38 MAPK , Calcium Channel , NF-κB , ROS | |
Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release. It also inhibit non-small cell lung carcinoma A549 cell inhibitory a... | |||
T3392 | Sinapine thiocyanate | P-gp , AChE | |
Sinapine Thiocyanate, is a derivative of Sinapine (S486605), an alkaloidal amine found in black mustard seeds. It is the choline ester of Sinapic Acid (S486800). It is also a phenolic-chloine conjugates, acting as anti-o... | |||
T5755 | Aloesin | Tyrosinase | |
Aloesin is a C-glycosylated chromone compound found in aloe (Liliaceae) that inhibits tyrosinase (IC50 = 0.9 mM), an enzyme responsible for catalyzing the first step of the conversion of tyrosine to melanin. | |||
T6520 | Grape Seed Extract | Grape Seed P.E. | Apoptosis , Others |
Grape Seed Extract (Grape Seed P.E.) is exudate from seeds of the grape plant Vitis vinifera, composed of oils and secondary plant metabolites (BIOFLAVONOIDS and polyphenols) credited with important medicinal properties. | |||
T5814 | Aurantiamide | TMC-58B | p38 MAPK , NF-κB |
Aurantiamide has anti-cancer, anti-inflammatory and antinociceptive activities, it may suppress the growth of malignant gliomas by blocking autophagic flux.Aurantiamide has an anti-neuroinflammatory effect on LPS stimula... | |||
T5S0018 | Betulonic acid | (+)-Betulonic acid,Betunolic acid,Liquidambaric acid | Parasite , HSV |
1. Betulonic acid (Liquidambaric acid) amide stimulated the regenerative response in hepatocytes under conditions of combined toxic exposure and promoted recovery of their qualitative and quantitative characteristics, wh... | |||
T6917 | Oleuropein | Apoptosis , Aromatase , ROS , PPAR | |
Oleuropein is an antioxidant polyphenol isolated from olive leaf. | |||
T5583 | Turanose | D-(+)-Turanose | Endogenous Metabolite |
D(+)-Turanose (D-(+)-Turanose) is a naturally occuring compound. It is a reducing disaccharide. | |||
T11685 | Isolongifolene | (-)-Isolongifolene | Apoptosis , Others |
Isolongifolene ((-)-Isolongifolene), a tricyclic sesquiterpene isolated from Murraya koenigii, exhibits antioxidant, anti-inflammatory, anticancer, and neuroprotective properties. It mitigates Rotenone-induced oxidative ... | |||
TN2883 | 3',4'-Dimethoxyflavone | Others , PARP | |
3',4'-Dimethoxyflavone is a standard compound of flavonoids with numerous medicinal activities. | |||
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カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-06981 | IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli) | Human | E. coli |
IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli... | |||
TMPJ-01467 | Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. OSM encodes a growth regulator, ... | |||
TMPK-00799 | ANXA1 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activ... | |||
TMPK-01291 | ANXA1 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | E. coli |
Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activ... | |||
TMPK-00077 | EPO/Erythropoietin Protein, Human, Recombinant | Human | HEK293 Cells |
Erythropoietin (EPO) is a circulating hormone conventionally considered to be responsible for erythropoiesis. In addition to facilitating red blood cell production, EPO has pluripotent potential, such as for cognition im... | |||
TMPK-00768 | ANXA1 Protein, Human, Recombinant (His) | Human | E. coli |
Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activ... | |||
TMPY-00176 | FNDC4 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
FNDC4 acts as an anti-inflammatory factor on macrophages and improves mouse model of induced colitis. FNDC4 could suppress osteoclast formation via NF-kappaB pathway and downregulation of CXCL10. Analysis of binding of F... | |||
TMPK-00759 | IgG1 Fc Protein, Human, Recombinant | Human | HEK293 Cells |
IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR) on phagocytic cells with high affinity. Fc fragment is demonstrated to mediate phagocytosis, trigger inflam... | |||
TMPK-01230 | CLEC2D Protein, Human, Recombinant (hFc & Avi) | Human | HEK293 Cells |
C-type lectin domain family 2, member D (CLEC2D) is implicated in the immune response. Pre-eclampsia and HIV infection have opposing immune responses. The contrasting expression of CLEC2D in HIV infection and pre-eclamps... | |||
TMPY-02128 | Serpin B1 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
SerpinB1 is an endogenous inhibitor of serine proteases recognized for its anti-inflammatory and host-protective properties. Serum SerpinB1 levels are elevated in patients with type 2 diabetes compared with that in healt... | |||
TMPY-04133 | UNC5B Protein, Human, Recombinant (His) | Human | HEK293 Cells |
The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium ... | |||
TMPY-00507 | UNC5B Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium ... | |||
TMPY-04003 | UNC5B Protein, Rat, Recombinant (hFc) | Rat | HEK293 Cells |
The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium ... | |||
TMPK-01137 | FAM3D Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
The physiological homeostasis of gut mucosal barrier is maintained by both genetic and environmental factors and its impairment leads to pathogenesis such as inflammatory bowel disease. A cytokine like molecule, FAM3D (m... | |||
TMPJ-01252 | CLEC2D Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
C-type lectin domain family 2, member D (CLEC2D) is implicated in the immune response. Sensing tissue damage is an ancient function of immune cells that is central to the regulation of inflammation, tissue repair, and im... | |||
TMPK-00056 | IL-10 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Interleukin 10 (IL10) is a key anti-inflammatory cytokine that can inhibit proinflammatory responses of both innate and adaptive immune cells. An association between IL10 and intestinal mucosal homeostasis became clear w... | |||
TMPK-00057 | IL-10 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Interleukin 10 (IL10) is a key anti-inflammatory cytokine that can inhibit proinflammatory responses of both innate and adaptive immune cells. An association between IL10 and intestinal mucosal homeostasis became clear w... | |||
TMPJ-00766 | ANXA1 Protein, Human, Recombinant | Human | E. coli |
Annexin A1 is the first characterized member of the annexin family of proteins and is able to bind to cellular membranes in a calcium-dependent manner, promoting membrane fusion and endocytosis. Annexin A1 has anti-infla... | |||
TMPH-00672 | Metalloprotease stcE Protein, E. coli O157:H7, Recombinant (His) | E. coli | E. coli |
Virulence factor that contributes to intimate adherence of enterohemorrhagic E.coli (EHEC) O157:H7 to host cells. Is able to cleave the secreted human mucin 7 (MUC7) and the glycoprotein 340 (DMBT1/GP340). Also cleaves h... | |||
TMPH-01702 | SMAD6 Protein, Human, Recombinant (E. coli, His & Myc) | Human | E. coli |
Transforming growth factor-beta superfamily receptors signaling occurs through the Smad family of intracellular mediators. SMAD6 is an inhibitory Smad (i-Smad) that negatively regulates signaling downstream of type I tra... | |||
TMPK-00650 | HLA-A*02:01 & B2M & MART-1 (ELAGIGILTV) Monomer Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Interleukin 10 (IL10) is a key anti-inflammatory cytokine that can inhibit proinflammatory responses of both innate and adaptive immune cells. An association between IL10 and intestinal mucosal homeostasis became clear w... | |||
TMPJ-00931 | Serpin A4 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Serpin Peptidase Inhibitor, Clade A (α-1 Antiproteinase, Antitrypsin), Member 4 (Serpin A4) is a member of the Serpin family. Serpin A4 exists as a monomer and some homodimers. Serpin A4 is expressed by the liver and sec... | |||
TMPJ-01424 | IL-10R alpha/IL-10RA Protein, Macaca mulatta, Recombinant (His) | Macaca Mulatta | HEK293 Cells |
Interleukin-10 Receptor alpha (IL-10 R alpha), also known as IL-10 R1, is transmembrane glycoprotein member of the class II cytokine receptor family. Interleukin-10 (IL10) is a key anti-inflammatory cytokine that is prod... | |||
TMPY-01909 | Elafin Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Elafin, also known as Elastase-specific inhibitor, Peptidase inhibitor 3, Protease inhibitor WAP3, Skin-derived antileukoproteinase, WAP four-disulfide core domain protein 14, PI3, WAP3 and WFDC14, is a secreted protein ... | |||
TMPY-02891 | PSG6 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
PSG6 is a pregnancy-specific glycoprotein(PSG). PSGs are secreted proteins produced by the rodent and primate placenta and play a critical role in pregnancy success. The levels of PSGs are highest during the third trimes... | |||
TMPY-04984 | CXCL17 Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Chemokine (C-X-C motif) ligand 17 (CXCL17) is the latest member of the chemokine family. CXCL17 is a potential oncogene and promising therapeutic target, is an independent biomarker of poor prognosis in patients with bre... | |||
TMPH-01676 | Meteorin-like/METRNL Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Hormone induced following exercise or cold exposure that promotes energy expenditure. Induced either in the skeletal muscle after exercise or in adipose tissue following cold exposure and is present in the circulation. A... | |||
TMPY-06836 | NR3C1 Protein, Human, Recombinant (His) | Human | E. coli |
NR3C1 (Nuclear Receptor Subfamily 3 Group C Member 1) is a Protein Coding gene. This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements ... | |||
TMPY-00410 | EPHX2 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Genetic variation in EPHX2 was significantly associated with risk of incident CHD in Caucasians, implicating EPHX2 as a potential cardiovascular disease-susceptibility gene. Single nucleotide polymorphisms (SNPs) in the ... | |||
TMPY-02597 | IL-37 Protein, Human, Recombinant | Human | E. coli |
Interleukin 1 family member 7, or interleukin 37 (IL1F7 / IL37 / IL-1H4) is a secretory protein belonging to the Interleukin 1 family. IL-1F7 was localized in human peripheral monocytic cells. It has been localized the e... | |||
TMPY-00186 | GHRH Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
The role of hypothalamic growth hormone-releasing hormone (GHRH) in the release of growth hormone (GH) from the pituitary is well established. Extra-hypothalamic growth hormone-releasing hormone (GHRH) plays an important... | |||
TMPY-05252 | Myeloperoxidase/MPO Protein, Human, Recombinant (His) | Human | HEK293 Cells |
MPO (myeloperoxidase) is a peroxidase enzyme secreted by activated leukocytes that plays a pathogenic role in cardiovascular disease, mainly by initiating endothelial dysfunction. Myeloperoxidase (MPO) is an important en... | |||
TMPJ-00751 | IgG4 hFc Protein, Human, Recombinant (aa 99-326) | Human | HEK293 Cells |
As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma ... | |||
TMPY-04550 | JNK2 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Mitogen-activated protein kinase 9 (MAPK9), also well known as c-Jun N-terminal kinase (JNK2), is a member of the MAP kinase subfamily belonging to the protein kinase superfamily. MAPK9 responds to activation by environm... | |||
TMPH-03753 | MYLK Protein, Human, Recombinant (His) | Human | E. coli |
Calcium/calmodulin-dependent myosin light chain kinase implicated in smooth muscle contraction via phosphorylation of myosin light chains (MLC). Also regulates actin-myosin interaction through a non-kinase activity. Phos... | |||
TMPH-01502 | Humanin Protein, Human, Recombinant (GST) | Human | E. coli |
Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective e... | |||
TMPH-01503 | Humanin Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective e... |
カタログ番号 | 製品名 | ||
---|---|---|---|
L4710 | Nonsteroidal Anti-Inflammatory Compound Library | 530 compounds | |
530 non-steroidal anti-inflammatory compounds for high-throughput and high-content screening. | |||
L6710 | Anti-Inflammatory Traditional Chinese Medicine Compound Library | 1246 compounds | |
A collection of 1246 TCM monomers with anti-inflammatory activity or targeting molecular therapeutic targets in inflammation, a powerful tool for drug discovery and mechanism study; | |||
L4700 | Immunology/Inflammation Compound Library | 4720 compounds | |
A unique collection of 4720 anti-inflammation compounds effective for high throughput screening and high content screening. | |||
L9810 | Anti-Fibrosis Compound Library | 1180 compounds | |
A unique collection of 1180 potential anti-fibrosis compounds, can be used in HTS and HCS; | |||
L6140 | Saccharide and Glycoside Natural Product Library | 362 compounds | |
A unique collection of 362 saccharides and glycosides compounds can be used for HTS and HCS; | |||
L6120 | Flavonoid Natural Product Library | 514 compounds | |
A unique collection of 514 flavonoids can be used for high throughput and high content screening; | |||
L6100 | Polyphenolic Natural Product Library | 635 compounds | |
A unique collection of 635 natural polyphenolic compounds for high throughput screening (HTS) and high content screening (HCS); | |||
L9000 | Apoptosis Compound Library | 1760 compounds | |
A unique collection of 1760 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening; | |||
L6110 | Alkaloid Natural Product Library | 464 compounds | |
A unique collection of 464 natural alkaloids can be used for high throughput and high content screening; | |||
L9610 | Cyclic Peptide Library | 55 compounds | |
55 species of cyclic peptide molecules for high-throughput and high-content screening; | |||
L6130 | Terpene Natural Product Library | 516 compounds | |
A unique collection of 516 natural terpenes and terpenoids can be used for high throughput and high content screening; | |||
L6810 | Traditional Chinese Medicine Monomer Library | 2755 compounds | |
A unique collection of 2755 compounds (TCM monomers) sourcing from traditional Chinese Medicines, is a powerful tool for drug discovery and research in mechanism; | |||
L6820 | Tobacco Monomer Library | 747 compounds | |
L6400 | Marine Natural Product Library | 144 compounds | |
A unique collection of 144 marine natural products for high throughput screening (HTS) and high content screening (HCS); | |||
L6730 | Anti-virus Traditional Chinese Medicine Monomer Library | 268 compounds | |
A collection of 268 TCM monomers with anti-virus activity. An effective tool for drug development and pharmacological studies. | |||
L5100 | Fluorochemical Library | 574 compounds | |
A unique collection of 574 fluorochemicals that can be used for high through-put screening (HTS) and high content screening (HCS); |