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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T5114 | Pyridaben | Calcium Channel , Parasite | |
Pyridaben is a METI acaricide that inhibits mitochondrial electron transport at complex I (METI; Ki = 0.36 nmol/mg protein in rat brain mitochondria). | |||
T22415 | Resorantel | Parasite | |
Resorantel is a safe, hydroxybenzanilide cestocide moderately effective against Paramphistomum spp and highly effective against Thysaniezia spp. and Moniezia. Resorantel has been used for the research of G. aegypticus an... | |||
T5839 | Phosalone | Parasite | |
Phosalone is an organophosphate chemical commonly used as an insecticide and acaricide. | |||
T15272 | Febantel | Parasite | |
Febantel is an anthelmintic. It is used for veterinary use on dogs, cats, cattle, sheep, goats, pig, and poultry against roundworms and tapeworms. | |||
T21727 | Ivermectin B1a | SARS-CoV , Parasite | |
Ivermectin B1a is the major (80%) component of commercially available ivermectin and a derivative of Avermectin B1a. | |||
T6623 | Oxibendazole | Apoptosis , Parasite | |
Oxibendazole is a benzimidazole drug that interferes with metabolic pathways, used to protect against roundworms, strongyles, threadworms, pinworms and lungworm infestations in horses and some domestic pets. | |||
T19714 | Fenpyroximate | Others | |
Fenpyroximate is an acaricide and insecticide. It blocking the mitochondrial electron transport in complex I. | |||
T7146 | Piperazine adipate | Parasite | |
Piperazine adipate is a potent broad spectrum anthelmintic. | |||
T38272 | Thiacloprid | AChR , Parasite | |
Thiacloprid is a neonicotinoid insecticide that acts as a selective agonist at insect nicotinic acetylcholine receptors (nAChRs) with IC50values of 2.7 and 860 nM forDrosophilanAChRs and M10 mouse fibroblast cells expres... | |||
T38845 | Dodecamethylpentasiloxane | Parasite | |
Dodecamethylpentasiloxane can be used as a bed bug insecticide. Dodecamethylpentasiloxane is a component of siloxane and can be used as silicone oil. | |||
T0997 | Temephos | Temefos | AChR , Parasite |
Temephos (Temefos) is a cholinesterase inhibitor. Temephos is an organothiophosphate insecticide, used in the therapy of water infested with disease-carrying insects including midges, mosquitoes, and black fly larvae. | |||
T0873 | Dinitolmide | Zoalene | Antibiotic , Parasite |
Dinitolmide (Zoalene), a poultry feed additive, is a coccidiostat for poultry. | |||
T3188 | RE-640 | CCR , Parasite | |
NSC-5844 (RE-640) (RE640) is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic activities. | |||
T4218 | Broxaldine | Brobenzoxaldine | Antibacterial , Antibiotic , Parasite , Antifungal |
Broxaldine (Brobenzoxaldine) is a small molecular drug with antiprotozoal activity. | |||
T2180 | Hexythiazox | Parasite | |
Hexythiazox is a mite growth regulator and a thiazolidine based acaricide that has long-lasting effects against many kinds of mites and is applied at any stage of the plant growth from budding to fruiting. | |||
T15409 | GNF179 | Parasite | |
GNF179 is an optimized 8,8-dimethyl IP analog. It exhibited the potency(4.8 nM against the multidrug resistant strain W2) in vitro metabolic stability and in vivo oral bioavailability. | |||
T14766 | BPH-715 | Others , Parasite | |
BPH-715 is a bisphosphonate, inhibits Plasmodium liver-stage growth. With an IC50 of 10 μM for Plasmodium exoerythrocytic forms in HepG2 cells[1]. | |||
T39849 | Propargite | Parasite | |
Propargite is a pesticide used to kill mites. Propargite induces β-cell necrosis preceded by DNA damage. Propargite induces MIN6 cell death with an IC 50 of 1 μM [1] . | |||
T0998 | Diazinon | Dimpylate | AChE , Parasite |
Diazinon (Dimpylate) is a thiophosphoric acid ester, functioning as a nonsystemic organophosphate insecticide that effectively targets and controls a variety of pests including cockroaches, silverfish, ants, and fleas. | |||
T7400 | RRX-001 | Apoptosis , Dehydrogenase , Parasite | |
RRx-001 is a potent inhibitor ofglucose 6-phosphate dehydrogenase(G6PD) and with potent antimalarial activity | |||
T1145 | Diminazene Aceturate | Others , Serine Protease , Parasite | |
Diminazene is a trypanocidal agent. | |||
T5471 | GUANABENZ | Adrenergic Receptor | |
GUANABENZ is a Central alpha-2 Adrenergic Agonist. The mechanism of action of guanabenz is as an Adrenergic alpha2-Agonist. | |||
T7901 | Emodepside | Bay 44-4400 | Parasite |
Emodepside (Bay 44-4400) is an anthelmintic drug that is effective against a number of gastrointestinal nematodes,with broad-spectrum anthelmintic activity. | |||
T13928 | Tioxazafen | Others , Parasite | |
Tioxazafen is a disubstituted oxadiazole, and is a broad-spectrum seed treatment nematicide. | |||
T10336 | Antimalarial agent 1 | Parasite | |
Antimalarial agent 1 is an effective antimalarial agent. | |||
T6532 | Hesperadin | Influenza Virus , Parasite , Aurora Kinase , Autophagy | |
Hesperadin(IC50=250 nM) effectively inhibits Aurora B. It potently reduces the activity of AMPK, MAPKAP-K1, MKK1, Lck, CHK1 and PHK, but it could not inhibit MKK1 activity in vivo. | |||
T8337 | Nequinate | Xanthine Oxidase , Parasite | |
Nequinate is an anticoccidial agent, preventing coccidiosis . | |||
T1172 | Diclazuril | R-64433 | Antibiotic , Parasite |
Diclazuril (R-64433) is a coccidiostat. | |||
T0471 | Decoquinate | Decoxy,Deccox | Parasite |
Decoquinate (Deccox) is a coccidiostat for poultry. | |||
T15775 | Lotilaner | GABA Receptor , Parasite | |
Lotilaner is a parasiticide. It is used as a potent non-competitive antagonist of insects GABACl receptors (IC50 of 23.84 nM for Drosophila melanogaster GABA receptor). It also has no effect on a dog GABAA receptor. | |||
T9741 | INE963 | Others | |
INE963 demonstrates potent cellular activity against Pf 3D7 (EC50 = 6 nM) and achieves "artemisinin-like" kill kinetics in vitro with a parasite clearance time of <24 h. INE963 is also potent against P. falciparum and P.... | |||
T21687 | Conoidin A | Parasite | |
Conoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties. It covalently binds to the peroxidatic Cys47 of TgPrxII, irreversibly inhibiting its hyperperoxidation ... | |||
T0066 | Dichlorophen | DDM,Dichlorophene | Antibacterial , Parasite , Antifungal |
Dichlorophen (DDM) is a nontoxic laxative vermicide of chlorinated phenol compound. Dichlorophen is used as a veterinary fungicide, anthelmintic, and anti-protozoan, as well as an ingredient in antimicrobial soaps and sh... | |||
T3202 | Fluensulfone | MCW-2 | Parasite |
Fluensulfone (MCW-2) is a new nematicide of the fluoroalkenyl thioether group that has significantly reduced environmental impact with low toxicity to non-target insects and mammals. | |||
T64320 | ML251 | Glucokinase , Parasite | |
ML251 is a potent novel nanomolar inhibitor of T. brucei and T. cruzi phosphofructokinase[1]. ML251 inhibits T. brucei PFK (IC50=0.37 μM) and T. cruzi PFK (IC50=0.13 μM). ML251 can be used for the research of parasite[1]... | |||
T3493 | Clofentezine | Bisclofentazin,Acaristop,Apollo | Others |
Clofentezine (Apollo) is an active substance of plant protection product used as the pesticide, acaricide. | |||
T5639 | Lufenuron | Fluphenacur | Parasite |
Lufenuron (Fluphenacur) is a chitin-synthesis inhibitor. | |||
T0376 | Crotamiton | Eurax,Crotamitone,Veteusan | Parasite |
Crotamiton (Eurax) is an antipruritic and a scabicidal agent available as a lotion or cream for topical use only. It is a colorless to slightly yellowish oil with a faint amine-like odor. It is miscible with methanol and... | |||
T1435 | Praziquantel | Pyquiton,Droncit,Biltricide | Calcium Channel , Antibiotic , Parasite |
Praziquantel (Droncit) increases the permeability of the tegument of susceptible worms, resulting in an influx and increase in intra-tegumental calcium leading to rapid contractions and paralysis of the worm's musculatur... | |||
T6452 | Closantel Sodium | Antibacterial , Parasite | |
Closantel is a salicylanilide anthelmintic compound; exhibits different anthelmintic spectra and apparent toxicity in mammals. | |||
T3266 | Lumefantrine | Benflumetol,dl-Benflumelol | Others , Parasite , Autophagy |
Lumefantrine (dl-Benflumelol) is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with artemether for improved efficacy. This combination therapy exerts its effects again... | |||
T0930 | Sulfadiazine | Sulphadiazine | Antibacterial , Antibiotic , Parasite , Autophagy |
Sulfadiazine (Sulphadiazine) is a synthetic pyrimidinyl sulfonamide derivative, short-acting bacteriostatic Sulfadiazine inhibits bacterial folic acid synthesis by competing with para-aminobenzoic acid. It is used in com... | |||
T8381 | Amodiaquine | Others , Histone Methyltransferase , Parasite | |
Amodiaquine is a synthetic aminoquinoline, used to treat malaria. | |||
T0286 | Bephenium (hydroxynaphthoate) | Bephenium Hydroxynaphthoate | Parasite |
Bephenium hydroxynaphthoate is a B-type AChR activator, formerly used in the treatment of hookworm infections and ascariasis. | |||
T10423 | AWZ1066S | Parasite | |
AWZ1066S is a highly specific anti-Wolbachia drug candidate for the short-course treatment of filariasis (EC50: 2.5 nM in cell assay). | |||
T3115 | Nicarbazin | Nicarbazine,Nicrazin,Nicoxin | Antibiotic , Parasite |
Nicarbazin (Nicoxin) is an equimolar complex of 4, 4'-Dinitrocarbanilide and 2-Hydroxy-4, 6-dimethylpyrimidine. A coccidiostat for poultry. | |||
T0323 | Oxantel Pamoate | Oxantel embonate | Others , Parasite |
Oxantel Pamoate (Oxantel embonate) is used as an Antinematodal agent. | |||
T10339 | Antitrypanosomal agent 1 | Parasite | |
Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor (IC50: 3.3 μM). Antitrypanosomal agent 1 inhibits glutathione reductase (IC50: 64.8 μM) and T. brucei (EC50: 1 μM). | |||
T16125 | MMV390048 | Parasite , PI4K | |
MMV390048 is an antimalarial agent and is a representative of a new chemical class of Plasmodium PI4K inhibitor (Kdapp=0.3 μM). MMV390048 binds to the ATP binding site of Plasmodium PI4K and does not bind to other P. fal... | |||
T4269 | Buparvaquone | Butalex,BW 720C | Antibiotic , Parasite |
Buparvaquone (BW 720C) is a hydroxynaphthoquinone antiprotozoal drug related to atovaquone and parvaquone. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T5708 | LUPENONE | Phosphatase , Parasite | |
Lupenone is a natural product isolated from Rhizoma Musae and has good anti-diabetic activity,and has anti-inflammatory activity.lupenone were potent PTP1B inhibitors with IC50 values of 15.11±1.23μM. | |||
T11811 | Laetanine | Parasite | |
Laetanine, exhibits antiplasmodial activity, a noraporphine alkaloid from Litsea laeta. | |||
T6S2024 | Harpagide | Antibacterial , Parasite | |
1. Harpagide has antibacterial activity. 2. Harpagide has antiviral activity. 3. Harpagide has anti-inflammatory activity. | |||
T5889 | Kojic acid | Tyrosinase , Parasite | |
Kojic acid is a fungal metabolite that inhibits tyrosinase, an enzyme involved in melanin synthesis, with an IC50 value of 30.6 μM for mushroom tyrosinase. | |||
TN1016 | Kukoamine A | NF-κB , Lipoxygenase , DNA/RNA Synthesis , Parasite | |
Kukoamine A possesses anticancer, cytoprotective, antioxidant, and anti-inflammatory activities, it also has neuroprotective effects through inhibiting oxidative stress and apoptosis after whole-brain irradiation (WBI) i... | |||
T1381 | Milbemycin oxime | Others , Antibiotic , Parasite | |
Milbemycin oxime is a broad spectrum antiparasitic, used as a veterinary drug. | |||
T5660 | Menthone | IL Receptor , TNF , NF-κB , Parasite | |
Menthone has anti-inflammary activity,, it can suppress the lipopolysaccharide (LPS)-induced proinflammatory cytokines, interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha (TNF-alpha),as well as nuclear factor k... | |||
T15277 | Fervenulin | Parasite | |
Fervenulin is isolated from a nematicidal actinomycete Streptomyces sp. CMU-MH021 with nematicidal activity. It also inhibits egg hatch and J2 mortality of M. incognita (MICs: 30 μg/mL and 120 μg/mL, respectively). | |||
TN6730 | Epoxyazadiradione | NF-κB | |
Epoxyazadiradione is an extract from Neem (Azadirachta indica) plant and may induce mitochondrial apoptosis and inhibition of NF-kB in human cervical cancer cells. | |||
TN1610 | Epimagnolin A | Parasite | |
Epimagnolin A is a lignan obtained from the flower buds of Magnolia fargesii, which is traditionally used in Asian medicine for treating headache and nasal congestion. | |||
T5800 | Allosecurinine | Allosecurinin | Antifungal |
Allosecurinine has Antifungal Activity. | |||
T13539 | Allopurinol riboside | Others , Endogenous Metabolite , Parasite , Drug Metabolite | |
Allopurinol riboside is a metabolite of allopurinol and shows effective activities against parasites. | |||
TN3466 | Atherosperminine | cAMP , Calcium Channel , AChR , Parasite | |
Atherosperminine shows cholinesterase inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Atherosperminine shows strong anti-plasmodial activity against Plasmodium falciparum, with t... | |||
TN1100 | Nepodin | transporter , COX , AMPK , Parasite | |
Nepodin has antimalarial, and anti-inflammatory activities, it shows significant cyclooxygenase (COX) inhibitory activity. Nepodin has an antidiabetic effect, which is at least partly mediated by stimulation of GLUT4 tra... | |||
T5771 | Hypocrellin A | Antibacterial , PKC , Parasite | |
Hypocrellin A is PKC inhibitor, has light-induced antitumor,antifungal and antiviral activities, it also exerts immunomodulatory effects on MHC-restricted presentation of antigen. | |||
TN4660 | Niranthin | Anti-infection , HBV , PAFR , Topoisomerase | |
Niranthin is a potent anti-leishmanial agent, inhibits the relaxation activity of heterodimeric type IB topoisomerase of L. donovani and acts as a non-competitive inhibitor interacting with both subunits of the enzyme. N... | |||
T0690 | Quinine | Potassium Channel , Platelet aggregation , Parasite | |
Quinine is a natural cinchona alkaloid that has been used for centuries in the prevention and therapy of malaria. Quinine is also used for idiopathic muscle cramps. Quinine therapy has been associated with rare instances... | |||
TN6512 | Tectol | Transferase , Parasite | |
Tectol has anti-plasmodial activity, it as a moderately active growth inhibitor with an IC50 3.44±0.20μM. It exhibited significant activity against human leukemia cell lines HL60 and CEM. Tectol may cause itchy dermatiti... | |||
TN1860 | Licoflavone B | ATPase , Anti-infection , Parasite | |
Licoflavone B has schistosomicidal activity, it showed high S. mansoni ATPase (IC50 of 23.78 μM) and ADPase (IC50 of 31.50 μM) inhibitory activities. | |||
T4S0590 | Columbin | Phospholipase , COX , Parasite | |
1. Columbin has anti-inflammatory activity. 2. Columbin has chemopreventive ability against human colon cancer. 3. Columbin inhibits PLA2 hydrolysis of ghost RBC in a dose-dependent fashion. | |||
T2S2172 | Nerolidol | (±)-Nerolidol,Peruviol | Others , Endogenous Metabolite , Antibacterial , Parasite , Antifungal |
Nerolidol (Peruviol) shows sedative effects in animals, oxidative process plays a crucial role on neuronal pathological consequence. Nerolidol is mainly related to ROS and DNA single strand breaks generated by the presen... | |||
T0969 | Doramectin | Dectomax,Cyclohexylavermectin B1 | Others , Antibiotic , Parasite |
Doramectin (Dectomax) is an antiparasitic agent. | |||
TN7103 | 13,21-Dihydroeurycomanone | Pasakbumin C | Anti-infection , Parasite |
13,21-Dihydroeurycomanone (Pasakbumin C) is a natural product isolated from the root of Eurycoma longifolia with antiparasitic activity such as Plasmodium falciparum and Toxoplasma gondii. | |||
TN2239 | Strictosamide | ATPase , Potassium Channel , Sodium Channel , Parasite , Antifungal | |
Strictosamide possesses antibacterial and antiviral activities, it also may have important effects on inflammation and inflammatory pain. | |||
T5780 | HYPOCRELLIN B | Apoptosis , Parasite , Antifungal | |
HYPOCRELLIN B are photosensitive pigments isolated from Hypocrella bambusae Sacc. Hypocrellin B causes DNA strand breakage, induces apoptosis in ovarian cancer cells, and inhibits proliferation of Staphylococcus by incre... | |||
T6S0084 | Tuberostemonine | Tuberstemonine | Parasite |
1. Tuberostemonine (Tuberstemonine) exhibits relatively higher intestinal permeabilities. 2. Tuberostemonine acts in part as an open-channel blocker at the crayfish neuromuscular junction. | |||
TN1432 | Bacopasaponin C | Anti-infection , GABA Receptor , NMDAR | |
Bacopasaponin C may have antioxidant activity, it also shows anti-leishmanial property. | |||
TWS2045 | Bruceine D | Apoptosis , Antiviral , Gamma-secretase , Parasite | |
1. Bruceine D from Brucea javanica, may have the potential to be used as a natural viricide, or a lead compound for new viricides. 2. Bruceine D inhibits the growth of three pancreatic cancer cell lines, i.e., PANC-1, SW... | |||
T10835 | Cletoquine | Desethylhydroxychloroquine | Parasite , Antifection |
Cletoquine is a major active metabolite of Hydroxychloroquine. Cletoquine has the ability to against the chikungunya virus (CHIKV). Cletoquine has antimalarial effects and has the potential for autoimmune disease treatme... | |||
T0896 | Furaltadone hydrochloride | Furaltadone HCl | Antibacterial , Antibiotic , Parasite |
Furaltadone hydrochloride (Furaltadone HCl) is an antibacterial and shows distinct curative effect in the treatment of coccidiosis. | |||
T3792 | Ajugol | Leonuride | Parasite |
Ajugol (Leonuride) shows some trypanocidal potential against Trypanosoma brucei rhodesiense (IC50 values 29.3–73.0 ug/ml). | |||
T0433 | Artesunate | WR-256283 | Virus Protease , Ferroptosis , STAT , Parasite |
Artesunate (WR-256283) is part of the artemisinin group of drugs that treat malaria. It is a semi-synthetic derivative of artemisinin that is water-soluble and may therefore be given by injection. It is on the World Heal... | |||
T0938 | Thiabendazole | 2-(4-Thiazolyl)benzimidazole | Microtubule Associated , Mitochondrial Metabolism , Parasite |
Thiabendazole (2-(4-Thiazolyl)benzimidazole) is a benzimidazole derivative with anthelminthic property. | |||
T10388 | Asparagusic acid | Parasite | |
Asparagusic acid is unique to asparagus. It is responsible for the odorous urine excreted after eating asparagus. Its derivatives ihydroasparagusic acid have an anti-inflammatory effect. | |||
T3254 | PHYTOL | trans-Phytol,(E)-Phytol | Antibacterial , PPAR , Parasite |
PHYTOL (trans-Phytol) , a diterpene alcohol from chlorophyll widely used as a food additive and in medicinal fields, shows antinociceptive and antioxidant activities as well as anti-inflammatory and antiallergic effects.... | |||
T6S0214 | Dl-Maackiain | (+)-Maackiain,Demethylpterocarpin | Apoptosis , Parasite |
1. dl-Maackiain (Demethylpterocarpin) induces apoptosis and growth suppression 2. MAK1 is the second functional gene cloned from Maackiain detoxification. | |||
TN1341 | 8-Deoxygartanin | Beta Amyloid , NF-κB , Parasite | |
8-Deoxygartanin is a butyrylcholinesterase (BChE) selective inhibitor, it exhibits significant inhibition of self-induced α2-amyloid (Aα2) aggregation, it has multifunctional activities against Alzheimer's disease (AD) a... | |||
T2827 | Asiatic acid | Asiantic acid,Dammarolic acid | Apoptosis , p38 MAPK , Parasite |
Asiatic acid (Dammarolic acid) is the aglycone of asiaticoside used in wound healing with antioxidant, anti-inflammatory, and neuroprotective properties. | |||
TN2027 | Oxysanguinarine | 8-Oxosanguinarine,Hydroxysanguinarine | Parasite |
Oxysanguinarine (Hydroxysanguinarine) possesses antiplatelet aggregation activity, it has potential inhibitory properties against the dengue virus. | |||
T6447 | Clindamycin | Clinimycin,Sobelin,Chlolincocin | Antibacterial , Antibiotic |
Clindamycin (Sobelin) dissociates peptidyl-tRNA from the bacterial ribosome, thereby disrupting bacterial protein synthesis. Clindamycin is a semisynthetic broad-spectrum antibiotic produced by chemical modification of t... | |||
T7938 | Quinidine | Parasite | |
Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria. | |||
T4593 | ISOPIMPINELLIN | 5,8-Dimethoxypsoralen,4,9-Dimethoxypsoralen | Antiviral , DNA/RNA Synthesis , Parasite |
Isopimpinellin (4,9-Dimethoxypsoralen) is a natural product isolated from the roots of Pimpinella saxifrage with antiviral and antileishmanial activity. | |||
T4333 | Quinine dihydrochloride | Quinine bimuriate | Others |
Quinine dihydrochloride (Quinine bimuriate) is a primary alkaloid of various species of Cinchona (Rubiaceae). It is also an antimalarial and muscle relaxant (skeletal). | |||
T0819 | Spiramycin | Espiramicin,Sequamycin,Rovamycin,Provamycin,Formacidine | Antibacterial , Antibiotic , Parasite |
Spiramycin (Rovamycin) is a macrolide antibiotic produced by Streptomyces ambofaciens. The drug is effective against gram-positive aerobic pathogens, N. gonorrhoeae, and staphylococci. It is used to treat infections caus... | |||
T1155 | Mebendazole | Telmin,Mebenvet,Vermox,Pantelmin | Apoptosis , Microtubule Associated , Parasite |
Mebendazole (Mebenvet) is a hedgehog inhibitor, used as an antihelminthic. | |||
T8259 | Doxycycline monohydrate | MMP , Antibacterial , Antibiotic , Parasite | |
Doxycycline monohydrate is an inhibitor of metalloproteinase (MMP) | |||
T0012 | Cinchonine | LA40221,(8R,9S)-Cinchonine | Apoptosis , P-gp , Parasite |
Cinchonine (LA40221), a local anesthetic of the amide type, now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local narcotics and its parenteral use is restricted to spi... | |||
T3718 | Santonin | α-santonin,alpha-Santonin,Semenen | Others , Parasite |
Santonin (alpha-Santonin) is a potent antiparasitic agent. | |||
T6841 | Fumagillin | NSC9168,Amebacilin | Others , HIV Protease , Antibiotic , Parasite |
Fumagillin (Amebacilin) is a selective and potent irreversible inhibitor of Methionine aminopeptidase 2 (MetAP2), used as an antibiotic to treat microsporidiosis. | |||
T2S2046 | Bruceine A | Dihydrobrusatol,NSC31616 | Antibiotic , Parasite |
Bruceine A (NSC-31616)(NSC-310616; Dihydrobrusatol) is a natural quassinoid compound extracted from the dried fruits of Brucea javanica (L.); are potential candidates for the treatment of canine babesiosis. | |||
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カタログ番号 | 製品名 | Species | Expression System |
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TMPY-04180 | PfLDH Protein, P. falciparum, Recombinant (His) | P. falciparum | E. coli |
Plasmodium falciparum lactate dehydrogenase (PfLDH) is a key enzyme for energy generation of malarial parasites and is considered to be a potential antimalarial target. The ability of PfLDH- or PfIDEh-based immuno-PCR as... | |||
TMPH-03634 | GRA3 Protein, Toxoplasma gondii, Recombinant (His) | Toxoplasma gondii | E. coli |
Direct host-parasite interaction occurs at the cytoplasmic faces of the parasitophorous vacuole membrane (PVM) and the host endoplasmic reticulum (ER) membrane via GRA3 and host CAMLG association. Direct insertion of GRA... | |||
TMPH-03142 | Plasmepsin-2 Protein, Plasmodium falciparum, Recombinant (E. coli, His & Myc) | Plasmodium falciparum | E. coli |
During the asexual blood stage, participates in initial cleavage of native host hemoglobin (Hb) resulting in Hb denaturation. May cleave preferentially denatured hemoglobin that has been cleaved by PMI. Digestion of host... | |||
TMPH-03140 | Plasmepsin-1 Protein, Plasmodium falciparum, Recombinant (His) | Plasmodium falciparum | E. coli |
During the asexual blood stage, catalyzes the initial cleavage of native host hemoglobin (Hb) resulting in Hb denaturation; specifically cleaves between Phe-33 and Leu-34 of Hb alpha-chain. Digestion of host Hb is an ess... | |||
TMPH-03141 | Plasmepsin-2 Protein, Plasmodium falciparum, Recombinant (His & Myc) | Plasmodium falciparum | Baculovirus Insect Cells |
During the asexual blood stage, participates in initial cleavage of native host hemoglobin (Hb) resulting in Hb denaturation. May cleave preferentially denatured hemoglobin that has been cleaved by PMI. Digestion of host... | |||
TMPK-01305 | CD43 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
CD43 (leukosialin) is a large sialoglycoprotein abundantly expressed on the surface of most cells from the hematopoietic lineage. CD43 is directly involved in the contact between cells participating in a series of events... | |||
TMPK-00832 | CD43 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CD43 (leukosialin) is a large sialoglycoprotein abundantly expressed on the surface of most cells from the hematopoietic lineage. CD43 is directly involved in the contact between cells participating in a series of events... | |||
TMPK-00827 | CD43 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
CD43 is a large transmembrane protein involved in T cell activation. Previous studies of CD43-/- mice in viral models have demonstrated a role for CD43 in Th1/Th2 skewing, activation of Foxp3 Treg, and T cell apoptosis. ... | |||
TMPJ-01217 | Mgl2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Macrophage galactose N-acetyl-galactosamine-specific lectin 2(Mgl2), also known as CD301b, is a 38 kDa member that belongs to the C-type lectin family. Two MGL proteins are encoded by separate genes in the mouse, but sha... | |||
TMPY-01771 | Latexin Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Latexin, also known as endogenous carboxypeptidase inhibitor, tissue carboxypeptidase inhibitor, TCI, ECI, and LXN, is a cytoplasm protein that belongs to the protease inhibitor I47 (latexin) family. It is highly express... | |||
TMPY-03968 | Secretogranin II Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Kit ligand, also known as Hematopoietic growth factor KL, Mast cell growth factor, Steel factor, Stem cell factor, c-Kit ligand, Kitlg and KITL, is a single-pass type I membrane protein that belongs to the SCF family. KI... | |||
TMPY-01027 | Mast Cell Protease-1/MCPT-1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Mast Cell Protease 1 (MMCP-1), also known as MCP-1, MCPT-1 and β-chymase, is a member of the Chymase family of chymotrypsin-like serine proteases. MCPT-1 is a 26 kDa β-chymase that is a component of mast cell granules. I... |
カタログ番号 | 製品名 | ||
---|---|---|---|
L1800 | Anti-Infection Compound Library | 2938 compounds | |
A unique collection of 2938 anti-infective compounds including anti-bacterial, anti-fungi, anti-Human Cytomegalovirus (HCMV), anti-HIV, anti-SARS, anti-influenza, etc; | |||
L4510 | Anti-Parasitic Compound Library | 419 compounds | |
419 well-chosen unique anti-parasitic small molecules; | |||
L6500 | Microbial Natural Product Library | 550 compounds | |
A unique collection of 550 microbial natural products for high throughput screening (HTS) and high content screening (HCS); |