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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T38964 | Peripheral Myelin P0 Protein (180-199), mouse | Peripheral Myelin P0 Protein (180-199), mouse | |
Peripheral Myelin P0 Protein (180-199), derived from mice, is a purified component of the myelin found in the peripheral nerves. This protein serves as a neuritogenic peptide, initiating the growth of neuronal processes. | |||
T40925 | Peripheral Myelin Protein P2 (53-78), bovine | Peripheral Myelin Protein P2 (53-78), bovine | |
Bovine Peripheral Myelin Protein P2 (53-78) is a derivative composed of amino acid residues 53 to 78 from the peripheral myelin P2 protein of bovine origin. It acts as a T cell epitope and is used to induce experimental ... | |||
T0957 | Isradipine | PN 200-110 | Calcium Channel , Autophagy |
Isradipine (PN 200-110) is a dihydropyridine calcium channel blockers with antihypertensive and vasodilator activities. Isradipine blocks the calcium entry through the calcium ion channels of coronary and peripheral vasc... | |||
T8511 | TM38837 | Cannabinoid Receptor | |
TM38837 is an antagonist of cannabinoid receptor type 1 (CB1), with potential for the treatment of obesity and type 2 diabetes. | |||
T15371 | Gardiquimod | TLR , HIV Protease | |
Gardiquimod is a TLR7/8 agonist. When used at concentrations below 10 μM, Gardiquimod specifically activates TLR7. Gardiquimod could inhibit HIV-1 infection of macrophages and activated peripheral blood mononuclear cells... | |||
T2121 | SW033291 | Dehydrogenase | |
SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues. | |||
T22782 | FGIN-1-27 | Others | |
high affinity agonist of the translocator protein | |||
T0993 | Methoxamine hydrochloride | Methoxamine HCl | Adrenergic Receptor |
Methoxamine hydrochloride (Methoxamine HCl) is an alpha-1 adrenergic agonist that causes prolonged peripheral VASOCONSTRICTION. | |||
T22459 | Xanthinol Nicotinate | Angioamin,Complamin | Others |
Xanthinol Nicotinate (Complamin) is a potent vasodilator that can easily enter the cell and causes an increase in glucose metabolism resulting in an increased energy. | |||
T0452 | Dropropizine | (±)-Dropropizine,UCB-196,UCB-1967 | Others |
Dropropizine (UCB-1967), a racemic non-opiate antitussive agent, is served as a cough suppressant. | |||
T6708 | Tolcapone | Tasmar,Ro 40-7592 | Apoptosis , Beta Amyloid , Transferase |
Tolcapone (Ro 40-7592) is a catechol-O-methyltransferase inhibitor used in the therapy of Parkinson disease as adjunctive therapy in combination with levodopa and carbidopa. | |||
T2148 | Carbidopa monohydrate | Carbidopa Hydrate,S(-)-Carbidopa | Decarboxylase , Aryl Hydrocarbon Receptor |
Carbidopa monohydrate (S(-)-Carbidopa) is an inhibitor of DOPA decarboxylase, preventing the conversion of levodopa to dopamine. | |||
T7748 | Dermorphin TFA | Others , Opioid Receptor | |
Dermorphin TFA is a new class of opioids-like peptides | |||
T1275 | Phentolamine mesylate | Phentolamine methanesulfonate,Phentolamine mesilate | Adrenergic Receptor |
Phentolamine mesylate (Phentolamine methanesulfonate) is a nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEAS... | |||
T0119 | Nitrendipine | BAY-E-5009,Bayotensin | Calcium Channel , Autophagy |
Nitrendipine (BAY-E-5009) is a calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtr... | |||
T21422 | Methylnaltrexone bromide | Relistor,MOA-728,MOA 728,Methylnaltrexone,MOA728 | Opioid Receptor |
Methylnaltrexone bromide (MOA-728) is one of the newer agents of peripherally-acting μ-opioid antagonists. Methylnaltrexone bromide acts to reverse some of the side effects of opioid drugs such as constipation without af... | |||
T6579 | Medetomidine hydrochloride | MPV785,Medetomidine HCl,Domitor | Adrenergic Receptor |
Medetomidine hydrochloride (MPV785) is a selective α2-adrenoceptor agonist, with Ki of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor. | |||
T1056 | Isoprenaline hydrochloride | NCI-c55630,Isoproterenol hydrochloride,Isoprenaline HCl | PI3K , Endogenous Metabolite , Adrenergic Receptor , PDE |
Isoprenaline hydrochloride (NCI-c55630) is a potent beta-adrenergic agonist with the peripheral vasodilator, bronchodilator, and cardiac stimulating properties. | |||
T1776 | Plerixafor | JM3100,AMD 3100,AMD-3329 | Virus Protease , HIV Protease , CXCR |
Plerixafor (AMD-3329), a chemokine receptor antagonist, blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4. | |||
T7404 | Dermorphin | Opioid Receptor | |
Dermorphin is agonist of μ-opioid receptor (MOR) agonist. | |||
T16411 | Otenzepad | AF-DX 116 | AChR |
Otenzepad (AF-DX 116) is a selective antagonist of M2 mAChR with IC50s of 386 nM and 640 nM for rat heart and rabbit peripheral lung. | |||
T3173 | DAA-1106 | DAA1106 | Others , GABA Receptor |
DAA-1106 is a potent and selective ligand for peripheral benzodiazepine receptor (PBR), acting as a potent and selective agonist at the peripheral benzodiazepine receptor. | |||
T70793 | Parogrelil Free Base | ||
Parogrelil Free Base is a phosphodiesterase inhibitor, improves claudication-limited exercise performance in patients with peripheral arterial disease. | |||
T21447 | Tolazoline | Priscol,Priscoline,Pridazole,Divascol,Vasimid,Benzalolin | Adrenergic Receptor |
Tolazoline (Benzalolin), a non-selective competitive α-adrenergic receptor antagonist, is used as a vasodilator to treat spasms of peripheral blood vessels. It has also been used successfully as an antidote to reverse th... | |||
T12478L | Pinacidil | S 1230,P 1134,S-1230,P-1134,P1134 | Potassium Channel |
Pinacidil (P 1134) is a guanidine that opens potassium channels and directly dilates peripheral blood vessels in small arteries, lowering blood pressure and peripheral resistance and producing fluid retention. | |||
T0712 | Suloctidil | ATPase , Platelet aggregation | |
Suloctidil is a peripheral vasodilator that was formerly used in the management of peripheral and cerebral vascular disorders. It is hepatotoxic and fatalities have occurred. | |||
T14551 | Bevenopran | CB-5945,ADL-5945 | Opioid Receptor |
Bevenopran (CB-5945) is a peripheral antagonist of μ-opioid receptor and can be used in studies about the treatment of opioid-induced bowel dysfunction. | |||
T25875 | Noberastine | R64947,T25875,R-64947,R 64947 | Histamine Receptor |
Noberastine (R 64947) is a novel histamine H1 antagonist with potent and specific peripheral antihistamine activity. | |||
T1169 | Moguisteine | BBR-2173 | Others |
Moguisteine (BBR-2173) is a new-type peripheral non-narcotic antitussive drug. | |||
T0317 | Buflomedil hydrochloride | Buflomedil HCl,Fonzylane,Loftyl | Adrenergic Receptor |
Buflomedil hydrochloride (Fonzylane), a vasodilator, is used in therapy of claudication or the symptoms of the peripheral arterial disease. | |||
T15779 | LP-533401 hydrochloride | 5-HT Receptor | |
LP-533401 hydrochloride is a peripheral Tph inhibitor that cannot cross the blood-brain barrier that inhibits 5-hydroxytryptamine synthesis and can be used to study periodontal disease and hepatic steatosis. | |||
T19211 | BM152054 | Others | |
BM152054 is a potent PPARγ ligand that induces glucose utilization in peripheral tissues by enhancing insulin action. | |||
T26939 | Cadralazine | ISF 2469,ISF-2469,ISF2469 | Others |
Cadralazine (ISF 2469) is a peripheral arteriolar vasodilator and can be used in studies about acting as an antihypertensive drug. | |||
T8762 | SW106065 | SW-106065 | Apoptosis |
SW106065 is a novel pharmacologic inducer of apoptosis in MPNST (malignant peripheral nerve sheath tumors).SW106065 is an apoptosis inducer in malignant peripheral nerve sheath tumors (MPNST). It inhibits ATP consumption... | |||
T9881 | Benzoquinamide hydrochloride | 3-carbamoyl-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride | Others |
Benzoquinamide hydrochloride (3-carbamoyl-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride) is an antiemetic agent and increases intra-arterial pressure due to the incre... | |||
T10502 | Benzcyclane | Benzcyclan,Bencyclane | Others , Platelet aggregation |
Benzcyclane (Benzcyclan) is an inhibitor of platelet aggregation and also a vasodilator that can be used in a variety of peripheral circulation disorders. | |||
T4509 | Inositol nicotinate | Inositol niacinate,Hexanicotol,Myo-Inositol hexanicotinate,Mesotal,Dilexpal,Inositol hexanicotinate | Others |
Inositol nicotinate (Mesotal) has the effect of lowering cholesterol and expanding peripheral blood vessels for hypercholesterolemia and atherosclerosis. | |||
T0806 | Flunarizine dihydrochloride | Flunarizine 2HCl,KW-3149,R14950 | Calcium Channel , Dopamine Receptor , Sodium Channel |
Flunarizine dihydrochloride (R14950) is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. Flunarizine dihydrochloride (R14950) is effective in the prophylaxis of mig... | |||
T0217 | Levodropropizine | (S)-(-)-Dropropizine,DF-526 | 5-HT Receptor , Histamine Receptor |
Levodropropizine ((S)-(-)-Dropropizine) is a histamine receptor inhibitor. It is used as an effective and very well tolerated peripheral antitussive drug. | |||
T7745 | Diclofensine hydrochloride | Ro 8-4650 hydrochloride | Others , Dopamine Receptor |
Diclofensine hydrochloride (Ro 8-4650 hydrochloride) is a Novel Antidepressant, on Peripheral Adrenergic Function | |||
T10244 | ACY-1083 | HDAC | |
ACY-1083 is a selective and brain-penetrating HDAC6 inhibitor (IC50: 3 nM) and effectively reverses chemotherapy-induced peripheral neuropathy. | |||
T0217L | (+)-Dropropizine | (+)-Dropropizine | Histamine Receptor |
(+)-Dropropizine can inhibit histamine receptor, anti-allergic, and reduce a cough by modulation of neuropeptides involved in the cough reflex and by interfering with stimulus activation of peripheral endings of sensory ... | |||
T28918 | Talviraline | Bay 10-8979,HBY 097,Bay10-8979,Bay-108979,Bay108979,Bay 108979,Bay-10-8979 | HIV Protease , DNA/RNA Synthesis |
Talviraline (Bay 10-8979) is an RNA-induced DNA polymerase inhibitor.Talviraline is a potent inhibitor of HIV-1-induced cell killing and HIV-1 replication in a variety of human cell lines, as well as in fresh human perip... | |||
T0126 | Diazoxide | SRG-95213,Sch-6783,Proglycem | ATPase , Potassium Channel , Autophagy |
Diazoxide (Proglycem) is a benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group. | |||
T1299 | 3-Pyridinemethanol | Nicotinyl alcohol,Roniacol | Others |
3-Pyridinemethanol (Roniacol) is an alcohol analog of NICOTINIC ACID which is a direct-acting peripheral vasodilator that causes flushing and may decrease blood pressure. It is used in vasospasm and threatened GANGRENE. | |||
T8311 | Obefazimod | ABX-464,ABX464 | HIV Protease |
Obefazimod (ABX-464) is a potent anti-HIV agent. ABX464 inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs) (IC50 : 0.1 μM - 0.5 μM) | |||
T1439 | Lacidipine | SN-305,GX-1048,GR-43659X | Apoptosis , Calcium Channel , Reactive Oxygen Species |
Lacidipine (SN-305) is a lipophilic dihydropyridine calcium antagonist with an intrinsically slow onset of activity. Due to its long duration of action, lacidipine does not lead to reflex tachycardia. It displays specifi... | |||
T0182L2 | (±) Clopidogrel hydrogen sulfate | Plavix,Clopidogrel hydrogen sulfate,Iscover | P2Y Receptor |
(±) Clopidogrel hydrogen sulfate (Iscover) , an antiplatelet agent pharmacologically and structurally analogous to ticlopidine, is used to inhibit blood clots in various conditions such as cerebrovascular disease, periph... | |||
T0029 | Procaine | Duracaine,Spinocaine,Novocaine,Vitamin H3 | Histone Demethylase , DNA/RNA Synthesis , Sodium Channel |
Procaine (Vitamin H3) is a local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. | |||
T5385 | Radiprodil | RGH-896 | NMDAR , iGluR |
Radiprodil (RGH-896) (RGH-896) is an orally active and selective NMDA NR2B receptors antagonist. It was a potential treatment of neuropathic pain associated with diabetic peripheral neuropathy (DPNP). |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T7907 | 7-Methoxyflavone | Others | |
7-Methoxyflavone isolated from Zornia brasiliensis with antinociceptive effects. | |||
T6795 | Carbidopa | (S)-(-)-Carbidopa,Lodosyn | Decarboxylase , Aryl Hydrocarbon Receptor |
Carbidopa (Lodosyn) is an aromatic-L-amino-acid decarboxylase inhibitor (IC50: 29±2 μM). It is used in PARKINSON DISEASE to reduce peripheral adverse effects of LEVODOPA. | |||
T4S0537 | Neoline | Bullatine B | Others |
Neoline (Bullatine B) shows analgesic/anti-inflammatory properties. | |||
T0070 | Pentoxifylline | Oxpentifylline,PTX,BL-191 | HIV Protease , PDE , Adenosine Receptor , Autophagy |
Pentoxifylline (PTX) modulates immunologic activity by stimulating cytokine production. Pentoxifylline is a methylxanthine derivative that inhibits phosphodiesterase and affects blood rheology. It also inhibits platelet ... | |||
TN1110 | Shanziside | Shanzhiside | IL Receptor |
Shanziside (Shanzhiside) has immunosuppressive activity, it shows significant inhibition of IL-2 secretion by phorbol myristate acetate and anti-CD28 monoclonal antibody co-stimulated activation of human peripheral blood... | |||
T3765 | L-asarinin | (-)-Episesamin | Others |
L-asarinin ((-)-Episesamin) reduces peripheral blood concentration of IL-12 and inhibits the expression of CXCR3 and TLR4, which means Asarinin may have a role on the TLR4 pathway and produce prolongation of allograft he... | |||
T5562 | Methyl nicotinate | methyl pyridine-3-carboxylate | Others |
Methyl nicotinate (methyl pyridine-3-carboxylate) is the methyl ester of that is used as an active ingredient as a rubefacient in over-the-counter topical preparations indicated for muscle and joint pain. The action of m... | |||
TN2322 | Yangambin | Calcium Channel , PAFR | |
Yangambin is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF); it has hypotensive effect, which is probably due to a peripheral vasodilatation that involves, at least, the inhibiti... | |||
T38248 | 2-Ethylpyrazine | Endogenous Metabolite , NO Synthase | |
2-Ethylpyrazine is present in roasted coffee beans and is a volatile compound .2-Ethylpyrazine induces vasodilation through the activity of endothelium-derived relaxing factors.2-Ethylpyrazine activates NO synthesis thro... | |||
T1626 | Prostaglandin E1 | PGE1,Alprostadil | Endogenous Metabolite , Prostaglandin Receptor |
Prostaglandin E1 (Alprostadil) is the naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Prostaglandin E1 is a potent vasodilator agent that increases peripheral blood flow, in... | |||
TN1861 | Licoflavone C | 4',5,7-Trihydroxy-8-prenylflavone | Antioxidant , Antifungal |
Licoflavone C (4',5,7-Trihydroxy-8-prenylflavone) is an isoprenoid-based flavonoid compound isolated from the roots of Glycyrrhiza inflata, which possesses antioxidant and antifungal activities, and is known to have a pr... | |||
T0791 | Reserpine | Serpalan,Serpasil,Serpivite | Others , Potassium Channel , MRP , Monoamine Transporter , Autophagy |
Reserpine (Serpalan) is an alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotoni... | |||
T0848 | L-DOPA | Levodopa,3,4-Dihydroxyphenylalanine | Dopamine Receptor , Endogenous Metabolite |
L-DOPA (Levodopa) is an amino acid precursor of dopamine with antiparkinsonian properties. Levodopa is a prodrug that is converted to dopamine by DOPA decarboxylase and can cross the blood-brain barrier. When in the brai... | |||
T4A2399 | Cinobufotalin | IL Receptor , Akt , MRP , P-gp | |
Cinobufotalin is a main cardiac toxin in toad, it is a novel anti-HCC agent, it induces growth inhibition and apoptosis in cultured HCC cells through ceramide production. Cinobufotalin is also an effective reversal agent... | |||
T2563 | Acetyl-L-carnitine hydrochloride | Acetyl L-carnitine hydrochloride,O-Acetylcarnitine,O-acetyl-L-carnitine,O-Acetyl-L-carnitine hydrochloride | Others , Endogenous Metabolite |
Acetyl-L-carnitine hydrochloride (Acetyl L-carnitine hydrochloride) is a nutritional supplement composed of the hydrochloride salt form of the acetylated form of the endogenously produced L-carnitine, with potential neur... | |||
T3S0209 | Vincristine | ERK , p38 MAPK , NF-κB , Akt , JNK , mTOR | |
Vincristine-induced nociceptive painful sensation, may be due to its potential of antioxidative, neuroprotective and calcium channel inhibitory action.Vincristine can treat MM, ERK1/2, Akt, and NF-κB inhibitors are pote... | |||
T24884 | Tingenone | Maytenin,Maitenin,Tingenin A,Tingenon | |
Tingenone is a pentacyclic triterpene. It induces peripheral antinociception due to opioidergic activation. | |||
TN5187 | Triptoquinone B | IL Receptor | |
Triptoquinone B is a novel interleukin-1 inhibitor, shows extremely potent inhibitory activities against interleukin-lα and β releases for human peripheral mononticlear cells, it shows the significant immunosuppressive a... | |||
T22357 | Lobeline sulfate | Lobelin sulphate | Others |
Lobelin sulphate is an alkaloid that has actions similar to nicotine on nicotinic cholinergic receptors but is less potent. It has a variety of therapeutic uses including in insomnia, and smoking cessation, peripheral va... | |||
TN6054 | Norglaucine hydrochloride | ||
(+)-Norglaucine shows cytotoxic activity toward the tumor cell lines B16-F10 (mouse melanoma), HepG2 (human hepatocellular carcinoma), K562 (human chronic myelocytic leukemia) and HL-60 (human promyelocytic leukemia) and... | |||
TL0018 | Lobelin | AChR , Antifection | |
Inhalation challenge with capsaicin and rapid intravenous injection of Lobelin and alinamin indicated that peripheral c-fiber receptors were involved in the induction of coughing. | |||
T7009 | Soyacerebroside II | IL Receptor , Calcium Channel | |
Soyacerebroside II exhibits ionophoretic activity for Ca2+ ion. Soyacerebrosides I and II have modulating the cellular immune response effects, they show obvious inhibitory activity on IL-18 secretion in human peripheral... | |||
TN5138 | Teuclatriol | TNF , NF-κB , TLR | |
Teuclatriol was found to be one of the compounds responsible for the immunoinhibitory effect of Salvia mirzayanii, by inhibiting NF-κB signaling at doses of 312µM and higher. It showed a significant anti-proliferative e... | |||
T79983 | Flaccidoside II | Apoptosis | |
Flaccidoside II, an active triterpenoid saponin from Anemone flaccida rhizome, both inhibits proliferation and induces apoptosis in Malignant Peripheral Nerve Sheath Tumors (MPNSTs) cell lines and ameliorates collagen-in... | |||
T82764 | Cd1a | β-TRTX-cd1a,β-Theraphotoxin-cd1a | |
Cd1a, a β-toxin from the African spider Ceratogyrus darlingi, modulates calcium ion channels and inhibits human calcium ion channels (Ca v 2.2)(IC 50 2.6 μM) as well as mouse sodium ion channels (Na v 1.7). This compound... | |||
T4S0083 | Protostemonine | Others | |
1. Protostemonine has anti-inflammatory activity, it effectively attenuates LPS-induced inflammatory responses in vitro and in vivo; the beneficial effects are associated with the decreased phosphorylation of MAPK and AK... | |||
TN2766 | 2'-Hydroxydaidzein | Cannabinoid Receptor , Antioxidant | |
2'-Hydroxydaidzein is an isoflavonoid phytonutrient found in plant species, when a natural compound. 2'-Hydroxydaidzein has antioxidant activity, driven mainly by o-hydrogen bond dissociation enthalpy (BDE) and hydrogen ... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-01563 | PMP2 Protein, Human, Recombinant (His) | Human | E. coli |
Myelin P2 protein, also known as PMP2, is a cytosolic protein found primarily in peripheral nerves. It Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. PMP2 is a small, basic, and cytoplasmic... | |||
TMPJ-00913 | MPZ Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Myelin Protein P0 (MPZ) is a single-pass type I membrane glycoprotein which belongs to the myelin P0 protein family. MPZ contains one Ig-like V-type (immunoglobulin-like) domain, absent in the central nervous system. MPZ... | |||
TMPH-00969 | ATP5O Protein, Human, Recombinant (GST) | Human | E. coli |
ATP5O Protein, Human, Recombinant (GST) is expressed in E. coli. | |||
TMPH-00964 | ATP5PB Protein, Human, Recombinant (His & Myc) | Human | E. coli |
ATP5PB Protein, Human, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPY-03956 | Fas Ligand Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells su... | |||
TMPY-03274 | CXCL11 Protein, Human, Recombinant | Human | E. coli |
I-TAC, also known as CXCL11, is a small cytokine belonging to the CXC chemokine family. It is highly expressed in peripheral blood leukocytes, pancreas and liver, with moderate levels in thymus, spleen and lung and low e... | |||
TMPY-02956 | Apolipoprotein L/APOL1 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
APOL1, also known as apolipoprotein L1, is a minor apoprotein component of HDL (High-density lipoprotein) or 'good cholesterol' which is synthesized in the liver and also in many other tissues, including pancreas, kidney... | |||
TMPY-05510 | BDNF Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
BDNF is a member of thenerve growth factorfamily. It is highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. It also can be detected in heart, lung, skeletal muscle, testis, prostate and placenta. B... | |||
TMPJ-01065 | Noggin/NOG Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Mouse Noggin cDNA encodes a 232 amino acid (aa) residue precursor protein with 19 aa residue putative signal pept... | |||
TMPJ-00412 | VEGFR1/FLT-1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 ... | |||
TMPH-03350 | Pmp22 Protein, Rat, Recombinant (His) | Rat | E. coli |
Might be involved in growth regulation, and in myelinization in the peripheral nervous system. Pmp22 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular we... | |||
TMPH-00376 | IL-8/CXCL8 Protein, Chicken, Recombinant | Chicken | E. coli |
May be an autocrine factor that promotes the growth of fibroblasts and is involved in the neoplastic transformation of fibroblasts by v-Src. Chemotactic for peripheral blood mononuclear cells as well as for heterophils. ... | |||
TMPH-01434 | Hemoglobin subunit delta/HBD Protein, Human, Recombinant (GST & His) | Human | E. coli |
Involved in oxygen transport from the lung to the various peripheral tissues. Hemoglobin subunit delta/HBD Protein, Human, Recombinant (GST & His) is expressed in E. coli expression system with N-6xHis-GST tag. The predi... | |||
TMPJ-00063 | CD160 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
CD160 antigen is a Lipid-anchor that exists as a disulfide-linked homomultimer. CD160 contains one Ig-like V-type domain. The human CD160 precursor is a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181... | |||
TMPJ-01245 | UCMA Protein, Human, Recombinant | Human | E. coli |
C10orf49 is a secreted protein which encoded by the UCMA gene. It is a member of the UCMA family. C10orf49 is predominantly expressed in resting chondrocytes. It may be involved in the negative control of osteogenic diff... | |||
TMPH-02489 | ASCL2 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. ASCL2 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression... | |||
TMPH-01258 | DAG1 Protein, Human, Recombinant (His & Myc) | Human | Baculovirus Insect Cells |
The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epi... | |||
TMPY-00055 | LCAT Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Lecithin: cholesterol acyltransferase (LCAT) is the sole enzyme that esterifies cholesterol in plasma, thus determining the maturation of high-density lipoproteins. Because it maintains an unesterified cholesterol gradie... | |||
TMPH-01979 | SFTPB Protein, Human, Recombinant | Human | P. pastoris (Yeast) |
Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearl... | |||
TMPK-00835 | LCAT Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Lecithin:cholesterol acyltransferase (LCAT) is the only enzyme capable of esterifying cholesterol in plasma, thus determining the maturation of high-density lipoproteins. Because it maintains an unesterified cholesterol ... | |||
TMPH-00375 | IL-8/CXCL8 Protein, Chicken, Recombinant (His) | Chicken | E. coli |
May be an autocrine factor that promotes the growth of fibroblasts and is involved in the neoplastic transformation of fibroblasts by v-Src. Chemotactic for peripheral blood mononuclear cells as well as for heterophils. ... | |||
TMPK-00596 | SECTM1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
SECTM1 is a T/NK cell "co-stimulatory" molecule that is expressed in the peripheral blood by neutrophils and monocytes.Human monocytic cells also displayed a pronounced negative regulation of SECTM1 mRNA expression by LP... | |||
TMPJ-00463 | BDH2 Protein, Human, Recombinant (His) | Human | E. coli |
3-Hydroxybutyrate Dehydrogenase Type 2 belongs to the short-chain dehydrogenases/reductases (SDR) family. 3-Hydroxybutyrate Dehydrogenase Type 2 may play an important role in the peripheral utilization of 3-hydroxybutyra... | |||
TMPK-00257 | KIR3DL3 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Killer-cell immunoglobulin-like receptor (KIR) 3DL3 is a framework gene present in all human KIR haplotypes.KIR3DL3 has been shown to be constitutively expressed at a low RNA level in peripheral blood mononuclear cell (P... | |||
TMPK-00234 | CD84 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Chronic lymphocytic leukemia (CLL) is characterized by the accumulation of CD5 B lymphocytes in peripheral blood, lymphoid organs and bone marrow. The main feature of the disease is accumulation of the malignant cells du... | |||
TMPK-00256 | KIR3DL3 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Killer-cell immunoglobulin-like receptor (KIR) 3DL3 is a framework gene present in all human KIR haplotypes.KIR3DL3 has been shown to be constitutively expressed at a low RNA level in peripheral blood mononuclear cell (P... | |||
TMPJ-00532 | PADI4 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Protein-Arginine Deiminase Type-4 (PADI4) belongs to the Protein Arginine Deiminase family. PADI4 is expressed in eosinophils and neutrophils, but it is not expressed in peripheral monocytes or lymphocytes. PADI4 catalyz... | |||
TMPY-04321 | CHRNA5 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Genetic variation in the cluster on chromosome 15, encoding the nicotinic acetylcholine receptor subunits (CHRNA5-CHRNA3-CHRNB4), has shown strong associations with tobacco consumption and an additional risk increase in ... | |||
TMPY-04399 | TAOK3 Protein, Human, Recombinant (aa 1-411, His & GST) | Human | Baculovirus Insect Cells |
Serine/threonine-protein kinase TAO3, also known as cutaneous T-cell lymphoma-associated antigen HD-CL-9, CTCL-associated antigen HD-CL-9, Dendritic cell-derived protein kinase, JNK / SAPK-inhibitory kinase, Jun kinase-i... | |||
TMPK-01179 | CDH19 Protein, Human, Recombinant (MBP & Flag) | Human | E. coli |
Cadherins play an important role in tissue homeostasis, as they are responsible for cell-cell adhesion during embryogenesis, tissue morphogenesis, differentiation and carcinogenesis. Cadherins are inseparably connected w... | |||
TMPJ-00974 | XCL1 Protein, Human, Recombinant (hFc & His) | Human | HEK293 Cells |
Lymphotactin is a secreted protein which belongs to the intercrine gamma family. It is also a member of the XC chemokine family. XCL1 is found in spleen with highest level, lower in peripheral leukocytes and very low lev... | |||
TMPK-01065 | SEZ6 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform o... | |||
TMPK-00541 | SEZ6 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform o... | |||
TMPK-00459 | Fc gamma RIIIB/CD16b (NA2) Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Human Fc gamma RIIIB/CD16b Protein is a receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate a... | |||
TMPK-00588 | Apolipoprotein E/APOE4 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury... | |||
TMPK-00182 | PD-L1 Protein, Human, Recombinant (aa 19-238, His & Avi), Biotinylated | Human | HEK293 Cells |
B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor progr... | |||
TMPY-02045 | SECTM1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Secreted and transmembrane 1 (SECTM1), also known as K12, is a transmembrane and secreted protein with characteristics of a type 1a transmembrane protein of SECTM family. It is found in a perinuclear Golgi-like pattern a... | |||
TMPK-00763 | Apolipoprotein E/APOE3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated | Human | HEK293 Cells |
Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury... | |||
TMPH-03280 | Dystrophin Protein, Rat, Recombinant (His) | Rat | P. pastoris (Yeast) |
Anchors the extracellular matrix to the cytoskeleton via F-actin. Ligand for dystroglycan. Component of the dystrophin-associated glycoprotein complex which accumulates at the neuromuscular junction (NMJ) and at a variet... | |||
TMPJ-00074 | IL-18BP Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Interleukin-18-binding protein, also known as Tadekinig-alfa and IL18BP, contains 1 Ig-like C2-type domain. IL18BP is constitutively expressed and secreted in mononuclear cells. IL18BP functions as an IL18 inhibitor. IL1... | |||
TMPJ-01222 | LRRC25 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Leucine-rich repeat-containing protein 25(LRRC25) is a single-pass type I membrane protein and contains 3 LRR (leucine-rich) repeats. The protein expressed in plasmacytoid dendritic cells (PDC), monocyte-derived dendriti... | |||
TMPJ-01156 | PHLDA2 Protein, Human, Recombinant (His) | Human | E. coli |
Pleckstrin Homology-Like Domain Family A Member 2 (PHLDA2) is a peripheral membrane protein that belongs to the PHLDA2 family. PHLDA2 is expressed in the placenta and adult prostate gland. In the placenta, it is present ... | |||
TMPJ-01186 | TRIM Protein, Human, Recombinant (His) | Human | E. coli |
T-Cell Receptor-Associated Transmembrane Adapter 1 (TRAT1) is a single-pass type III membrane protein. TRAT1 exists as a disulfide-linked homodimer and is strongly expressed in the thymus, and to a lesser extent in the s... | |||
TMPK-00998 | SEZ6 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform o... | |||
TMPK-00997 | SEZ6 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform o... | |||
TMPK-00996 | SEZ6 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform o... | |||
TMPJ-00084 | RBP4 Protein, Human, Recombinant | Human | E. coli |
Retinol Binding Protein 4 (RBP4) is a member of the Lipocalin family and in the blood. RBP4 is the specific vector for retinol. RBP4 is expressed and secreted by adipose tissue, and is associated with insulin resistance.... | |||
TMPJ-00538 | LILRA3/CD85e Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Leukocyte immunoglobulin-like receptor subfamily A member 3 is also known as CD85 antigen-like family member E, Immunoglobulin-like transcript 6, ILT-6, Leukocyte immunoglobulin-like receptor 4, LIR-4 and Monocyte inhibi... | |||
TMPH-00423 | Tetanus toxin Protein, Clostridium tetani, Recombinant (B2M & His) | Clostridium tetani | E. coli |
Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynapt... | |||
TMPH-03128 | TSPO Protein, Pig, Recombinant (His & Myc & SUMO) | Sus scrofa (Pig) | E. coli |
Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynt... | |||
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A unique collection of 1408 cardiovascular diseases related compounds for high throughput screening (HTS) and high content screening (HCS); | |||
L7110 | Anti-Hypertension Compound Library | 678 compounds | |
678 hypertension-related small molecules for high-throughput and high-content screening. | |||
L2800 | Serotonin Receptor-Targeted Compound Library | 268 compounds | |
A unique collection of 268 compounds targeting serotonin receptors for high throughput screening and high content screening; | |||
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