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546

阻害剤

天然化合物

カタログ番号	製品名	別名	ターゲット
T11727	JPH203 dihydrochloride	KYT-0353 dihydrochloride	Others
	JPH203 dihydrochloride (KYT-0353 dihydrochloride) is a tyrosine analog, acts as a selective inhibitor of L-type amino acid transporter 1 (LAT1), and is used in cancer research.		Others
T12241	Norbinaltorphimine dihydrochloride	nor-BNI dihydrochloride,Nor-BNI dihydrochloride,nor-Binaltorphimine dihydrochloride,Nor-Binaltorphimine dihydrochloride	Opioid Receptor
			Opioid Receptor
T7821	DG172 dihydrochloride	DG172 (dihydrochloride),DG-172 dihydrochloride	PPAR
	DG172 dihydrochloride (DG-172 dihydrochloride) is an antagonist of PPARβ/δ(IC50 : 27 nM).		PPAR
T11345L	Lerociclib dihydrochloride	G1T38 dihydrochloride	CDK
	Lerociclib dihydrochloride (G1T38 dihydrochloride) is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 2 nM and 1 nM for CDK6/CyclinD3 and CDK4/CyclinD1, respectively.		CDK
T15374	Ipatasertib dihydrochloride	GDC-0068 dihydrochloride,RG-7440 dihydrochloride	Akt , PKA
	Ipatasertib dihydrochloride (GDC-0068 dihydrochloride) is a highly selective and ATP-competitive inhibitor of pan-Akt (IC50s: 5, 18 and 8 nM for Akt1, Akt2 and Akt3, respectively).		Akt , PKA
T22354	Levocetirizine Dihydrochloride	Xyzal Dihydrochloride,(-)-Cetirizine Dihydrochloride	Histamine Receptor
	Levocetirizine Dihydrochloride (Xyzal Dihydrochloride) is a third-generation peripheral H1-receptor antagonist. Acting as an antihistaminic agent, it specifically targets the histamine H1-receptor. Levocetirizine Dihydro...		Histamine Receptor
T13675	Elacestrant dihydrochloride	RAD1901 dihydrochloride	Estrogen/progestogen Receptor
	Elacestrant dihydrochloride (DA-DKRAD1901 dihydrochloride) is an orally available selective estrogen receptor degrader with IC50s of 48 for ERα and 870 nM for ERβ, respectively.		Estrogen/progestogen Receptor
T9012	Preq1-Dihydrochloride	pre-queuosine1 Dihydrochloride	Others
	Preq1-Dihydrochloride (pre-queuosine1 Dihydrochloride) is an intermediate of the queuosine pathway, it binds with high affinity to the aptamer of PreQ1 riboswitch, which attenuates protein expression.		Others
T3597	Cutamesine dihydrochloride	AGY94806 dihydrochloride,SA4503 (dihydrochloride),SA4503 dihydrochloride	Sigma receptor
	Cutamesine dihydrochloride (SA4503 dihydrochloride) is a selective σ1 receptor agonist (IC50: 17.4 nM). It shows selectivity for σ1 over σ2 receptors, and inhibits angiotensin II-induced cardiomyocyte hypertrophy in vitr...		Sigma receptor
T10358	Netarsudil Dihydrochloride	AR-13324 Dihydrochloride	ROCK
	Netarsudil Dihydrochloride (AR-13324 Dihydrochloride) is an inhibitor of Rho-associated protein kinase (ROCK) and norepinephrine transporter (NET) with effective in intraocular pressure (IOP) reduction.		ROCK
T4676	Sardomozide dihydrochloride	CGP 48664 dihydrochloride,Sardomozide dihydrochloride	Others
	Sardomozide dihydrochloride (CGP 48664 dihydrochloride) is an inhibitor of S-adenosylmethionine decarboxylase (SAMDC, IC50 = 5 nM).		Others
T9172	Simufilam dihydrochloride	PTI-125 dihydrochloride	Others
	Simufilam dihydrochloride (PTI-125 dihydrochloride) is a low toxicity, orally active filamin A (FLNA) activator, which can be used for the research of Alzheimer's disease. Simufilam dihydrochloride preferentially binds a...		Others
T12374	PAβN dihydrochloride	MC-207,110 dihydrochloride,Phe-Arg-β-naphthylamide dihydrochloride	Others , Antibacterial
	PAβN dihydrochloride (MC-207,110 dihydrochloride) is an inhibitor of efflux pump.		Others , Antibacterial
T4467	UAMC00039 dihydrochloride	UAMC 00039 dihydrochloride	Proteasome
	UAMC00039 dihydrochloride is a potent, reversible and competitive dipeptidyl peptidase II inhibitor with an IC50 of 0.48 nM.		Proteasome
T5135	Flupentixol dihydrochloride	Fupentixol Dihydrochloride,Flupenthixol dihydrochloride,(E/Z)-Flupentixol Dihydrochloride	Dopamine Receptor
	Flupentixol dihydrochloride is used in therapy of schizophrenia as well as in anxiolytic and depressive disorders.		Dopamine Receptor
T19069	TMB dihydrochloride	BM blue dihydrochloride,Sure Blue TMB dihydrochloride,3,3',5,5'-Tetramethylbenzidine dihydrochloride	Others
	TMB dihydrochloride (Sure Blue TMB dihydrochloride) is an enzyme-linked immunosorbent assays (ELISA) and an excellent colorimetric substrate for the detection of horseradish peroxidase (HRP)-labeled probes used in staini...		Others
T7153	Vanoxerine dihydrochloride	GBR-12909 dihydrochloride,I893 dihydrochloride	Dopamine Receptor
	Vanoxerine dihydrochloride (GBR-12909 dihydrochloride) is a potent inhibitor that blocks dopamine uptake (IC50 : 1-51 nM)		Dopamine Receptor
T11011	Dexpramipexole dihydrochloride	KNS-760704 dihydrochloride,R-(+)-Pramipexole dihydrochloride,(R)-Pramipexole dihydrochloride	Dopamine Receptor
	Dexpramipexole dihydrochloride (KNS-760704 dihydrochloride) ((R)-Pramipexole dihydrochloride) is a neuroprotective agent and is a weak non-ergoline dopamine agonist.		Dopamine Receptor
T5495	Decloxizine dihydrochloride	UCB 1402 dihydrochloride	Histamine Receptor
	Decloxizine dihydrochloride (UCB 1402 dihydrochloride) is a histamine 1 receptor antagonist.		Histamine Receptor
T7505	Azimilide Dihydrochloride	NE-10064 Dihydrochloride	Potassium Channel
	Azimilide Dihydrochloride (NE-10064 Dihydrochloride), a novel class III antiarrhythmic agent, blocks both the slowly activating (IKs) and rapidly activating (IKr) components of the delayed rectifier potassium current		Potassium Channel
T7309	TAS-103 dihydrochloride	TAS-103 (dihydrochloride),BMS-247615 dihydrochloride	Topoisomerase
	TAS-103 dihydrochloride (BMS-247615 dihydrochloride) is a novel anticancer agent targeting both topoisomerase (Topo) I and Topo II.		Topoisomerase
T6720	Vatalanib dihydrochloride	CGP-797870 dihydrochloride,ZK-222584 dihydrochloride,Vatalanib 2HCl,PTK787 dihydrochloride,Vatalanib (PTK787) 2HCl,CGP-79787 dihydrochloride	Apoptosis , VEGFR , PDGFR
	Vatalanib dihydrochloride (PTK787 dihydrochloride)(IC50=37 nM) is an inhibitor of VEGFR2/KDR. It exhibits less effective against VEGFR1/Flt-1 and 18-fold against VEGFR3/Flt-4.		Apoptosis , VEGFR , PDGFR
T2105	Veliparib dihydrochloride	ABT-888 dihydrochloride	PARP , Autophagy
	Veliparib dihydrochloride (ABT-888 dihydrochloride) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively. It is inactive to SIRT2.		PARP , Autophagy
T21648	CP-31398 dihydrochloride	CP 31398 dihydrochloride	p53
	CP-31398 dihydrochloride is a p53 stabilizer which stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines with mutant or wild-type p53.		p53
T26240	Surfen dihydrochloride	Aminokinuride dihydrochloride,Aminoquinuride dihydrochloride,NSC-12155,Aminokinuride 2HCl,Aminoquinuride 2HCl	FGFR , Antiviral , Antibiotic
	Surfen dihydrochloride (Aminoquinuride dihydrochloride) is a potent small molecule antagonist of heparin sulphate with antimicrobial and antiviral activity and inhibits anthrax lethal factor, coagulation factor X and let...		FGFR , Antiviral , Antibiotic
T10459	Banoxantrone dihydrochloride	AQ4N dihydrochloride,AZD1689 2HCl	NOS
			NOS
T12383	PD 168568 dihydrochloride	PD 168568 (dihydrochloride)	Dopamine Receptor
	PD 168568 dihydrochloride (PD 168568 (dihydrochloride)) is an orally active and selective antagonist of D4 dopamine receptor(Ki of 8.8 nM).		Dopamine Receptor
T2501	Canertinib dihydrochloride	CI-1033 dihydrochloride,PD-183805 dihydrochloride,Canertinib	EGFR
	Canertinib dihydrochloride (PD-183805 dihydrochloride) is the hydrochloride salt of an orally bio-available quinazoline with potential antineoplastic and radiosensitizing activities.		EGFR
T11500L	GSK3368715 dihydrochloride	EPZ019997 dihydrochloride,GSK3368715 2HCl,EPZ019997 2HCl	Histone Methyltransferase
			Histone Methyltransferase
T1791L	Ceritinib dihydrochloride	LDK378 dihydrochloride	IGF-1R , ALK
	Ceritinib dihydrochloride (LDK378 dihydrochloride) is a selective, orally bioavailable and ATP-competitive inhibitor of ALK tyrosine kinase(IC50 of 200 pM), and also inhibits IGF-1R, InsR, and STK22D (IC50 values of 8, 7...		IGF-1R , ALK
TQ0126	Mirodenafil dihydrochloride	SK-3530 dihydrochloride	PDE
	Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.		PDE
T22288	(1E)-CFI-400437 dihydrochloride	CFI-400437 dihydrochloride	PLK
	(1E)-CFI-400437 dihydrochloride (CFI-400437 dihydrochloride) is a selective and potent polo-like kinase 4 (PLK4) inhibitor.		PLK
T23132	Pentamidine dihydrochloride	MP-601205 dihydrochloride	Phosphatase , Antibacterial , Antibiotic , Parasite , Antifungal
	Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an aromatic diamidine agent with activity against a number of microorganisms including protozoa (Trypanosoma brucei, Leishmania spp., and Babesia spp.) and fungi...
T1786	Daclatasvir dihydrochloride	BMS-790052 dihydrochloride	HCV Protease
	Daclatasvir dihydrochloride (BMS-790052 dihydrochloride) is an orally available antiviral agent that inhibits the NS5A region of the hepatitis C virus (HCV) and is used in combination with other oral antiviral agents to ...		HCV Protease
T60248	4-Aminobenzamidine dihydrochloride	p-Aminobenzamidine dihydrochloride	Serine Protease
	4-Aminobenzamidine dihydrochloride (p-Aminobenzamidine dihydrochloride) is a strong trypsin inhibitor and a relatively weak inhibitor of urokinase type plasminogen activator (uPA) (K i =82 μM). 4-Aminobenzamidine can inh...		Serine Protease
T3213	Hematoporphyrin dihydrochloride	Hematoporphyrin IX dihydrochloride	Apoptosis , Others , Endogenous Metabolite
	Hematoporphyrin dihydrochloride (Hematoporphyrin IX dihydrochloride) is a substrate for affinity chromatography of heme-binding proteins.		Apoptosis , Others , Endogenous Metabolite
T61156	L-Lysyl-L-lysine dihydrochloride	Lysyllysine dihydrochloride	Others
	L-Lysyl-L-lysine dihydrochloride (Lysyllysine dihydrochloride) is an enzyme cleavable linker. L-Lysyl-L-lysine dihydrochloride can be used as facile linker for delivering multiple biologically active peptides.		Others
T14490	Talipexole dihydrochloride	Domnin,B-HT 920 dihydrochloride	Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
	Talipexole dihydrochloride (Domnin) is a dopamine D2 receptor agonist, α2-adrenoceptor agonist, and 5-HT3 receptor antagonist in both rat cortical and intestinal membrane fractions with Ki values of 0.35 μM and 0.22 μM, ...		Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
T38034	MAO-IN-M30 dihydrochloride	M 30 dihydrochloride	Monoamine Oxidase
	MAO-IN-M30 dihydrochloride (M 30 dihydrochloride) is a potent and brain selective monoamine oxidase (MAO) inhibitor (EC50 values are 37 and 57 nM for MAO-A and MAO-B, respectively). Also an iron chelator with antioxidant...		Monoamine Oxidase
T6423	BRL-15572 dihydrochloride	BRL 15573 dihydrochloride	5-HT Receptor
	BRL-15572 dihydrochloride (BRL 15573 dihydrochloride) is a 5-HT1D receptor antagonist with pKi of 7.9, also shows a considerable affinity at 5-HT1A and 5-HT2B receptors, exhibiting 60-fold selectivity over 5-HT1B recepto...		5-HT Receptor
T11227L	Eravacycline dihydrochloride	TP-434-046,TP-434 dihydrochloride	Antibacterial
	Eravacycline dihydrochloride (TP-434-046) is a potent and broad-spectrum antibacterial agent against six E. coli (MICs: 0.125-0.25 mg/L).		Antibacterial
T35328	H-1152 dihydrochloride	H-1152 2HCl,H-1152 dihydrochloride	ROCK
	H-1152 dihydrochloride (H-1152 2HCl) is a specific inhibitor of Rho-associated protein kinase (ROCK) with an IC50 of 12 nM and a Ki of 1.6 nM. H-1152 dihydrochloride inhibits PKA, PKC, PKG, Aurora A and CaMKII with IC50 ...		ROCK
T14998	Copanlisib dihydrochloride	BAY 80-6946 dihydrochloride	Apoptosis , PI3K , mTOR
	Copanlisib dihydrochloride (BAY 80-6946 dihydrochloride) is an ATP-competitive pan-class I PI3K inhibitor (IC50s: 0.5 nM, 0.7 nM, 3.7 nM and 6.4 nM for PI3Kα, PI3Kδ, PI3Kβ and PI3Kγ). Copanlisib dihydrochloride has super...		Apoptosis , PI3K , mTOR
T4327	Prexasertib dihydrochloride	LY2606368 (dihydrochloride),Prexasertib HCl,LY2606368	Apoptosis , Chk , S6 Kinase
	Prexasertib dihydrochloride (LY2606368) is an ATP-competitive CHK1 inhibitor (Ki: 0.9 nmol/L). in the cell-free assay, its IC50 values are 8 nM and 9 nM for CHK2 and RSK, respectively.		Apoptosis , Chk , S6 Kinase
T22831	Protein kinase inhibitor H-7 dihydrochloride	H-7 dihydrochloride	PKC
	Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor. Protein kinase inhibitor H-7 dihydrochloride (100 μM) significantly inhibits TPA (skin tumor promoter, 12-O-...		PKC
T16524	Philanthotoxin 74 dihydrochloride	PhTx-74 HCl,PhTx 74 dihydrochloride	GluR , iGluR
	Philanthotoxin 74 dihydrochloride is an antagonist of AMPAR with IC50s of 263 and 296 nM for GluR3 and GluR1.		GluR , iGluR
T12032	Mibefradil dihydrochloride	Ro 40-5967 (dihydrochloride)	Calcium Channel
	Mibefradil dihydrochloride (Ro 40-5967 (dihydrochloride)) is an blocker of calcium channel with moderate selectivity for T-type Ca2+ channels (T-type and L-type currents with IC50s of 2.7 μM and 18.6 μM, respectively).		Calcium Channel
T1110	Meclizine dihydrochloride	Meclozine dihydrochloride,NSC28728,Meclizine 2HCl	Apoptosis , Histamine Receptor
	Meclizine dihydrochloride (NSC28728) is a histamine H1 antagonist used in the treatment of motion sickness, vertigo, and nausea during pregnancy and radiation sickness.		Apoptosis , Histamine Receptor
T6146	Dorsomorphin dihydrochloride	BML-275 2HCl,Compound C dihydrochloride,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride	AMPK , Autophagy , TGF-beta/Smad
	Dorsomorphin dihydrochloride (BML-275 2HCl) is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity on structurally related kinases.		AMPK , Autophagy , TGF-beta/Smad
T6562	Latrepirdine dihydrochloride	Dimebolin dihydrochloride,Latrepirdine,Latrepirdine 2HCl,Dimebolin	Beta Amyloid , 5-HT Receptor , Adrenergic Receptor , GluR , Autophagy , Histamine Receptor
	Latrepirdine dihydrochloride (Dimebolin dihydrochloride) is an orally active, and neuroactive antagonist of multiple drug targets, including histamine receptors, GluR, and 5-HT receptors, used as an antihistamine drug.

Compounds

JPH203 dihydrochloride

T11727

Synonym: KYT-0353 dihydrochloride

Target: Others

Norbinaltorphimine dihydrochloride

T12241

Synonym: nor-BNI dihydrochloride,Nor-BNI dihydrochloride,nor-Binaltorphimine dihydrochloride,Nor-Binaltorphimine dihydrochloride

Target: Opioid Receptor

DG172 dihydrochloride

T7821

Synonym: DG172 (dihydrochloride),DG-172 dihydrochloride

Target: PPAR

Lerociclib dihydrochloride

T11345L

Synonym: G1T38 dihydrochloride

Target: CDK

Ipatasertib dihydrochloride

T15374

Synonym: GDC-0068 dihydrochloride,RG-7440 dihydrochloride

Target: Akt, PKA

Levocetirizine Dihydrochloride

T22354

Synonym: Xyzal Dihydrochloride,(-)-Cetirizine Dihydrochloride

Target: Histamine Receptor

Elacestrant dihydrochloride

T13675

Synonym: RAD1901 dihydrochloride

Target: Estrogen/progestogen Receptor

Preq1-Dihydrochloride

T9012

Synonym: pre-queuosine1 Dihydrochloride

Target: Others

Cutamesine dihydrochloride

T3597

Synonym: AGY94806 dihydrochloride,SA4503 (dihydrochloride),SA4503 dihydrochloride

Target: Sigma receptor

Netarsudil Dihydrochloride

T10358

Synonym: AR-13324 Dihydrochloride

Target: ROCK

Sardomozide dihydrochloride

T4676

Synonym: CGP 48664 dihydrochloride,Sardomozide dihydrochloride

Target: Others

Simufilam dihydrochloride

T9172

Synonym: PTI-125 dihydrochloride

Target: Others

PAβN dihydrochloride

T12374

Synonym: MC-207,110 dihydrochloride,Phe-Arg-β-naphthylamide dihydrochloride

Target: Others, Antibacterial

UAMC00039 dihydrochloride

T4467

Synonym: UAMC 00039 dihydrochloride

Target: Proteasome

Flupentixol dihydrochloride

T5135

Synonym: Fupentixol Dihydrochloride,Flupenthixol dihydrochloride,(E/Z)-Flupentixol Dihydrochloride

Target: Dopamine Receptor

TMB dihydrochloride

T19069

Synonym: BM blue dihydrochloride,Sure Blue TMB dihydrochloride,3,3',5,5'-Tetramethylbenzidine dihydrochloride

Target: Others

Vanoxerine dihydrochloride

T7153

Synonym: GBR-12909 dihydrochloride,I893 dihydrochloride

Target: Dopamine Receptor

Dexpramipexole dihydrochloride

T11011

Synonym: KNS-760704 dihydrochloride,R-(+)-Pramipexole dihydrochloride,(R)-Pramipexole dihydrochloride

Target: Dopamine Receptor

Decloxizine dihydrochloride

T5495

Synonym: UCB 1402 dihydrochloride

Target: Histamine Receptor

Azimilide Dihydrochloride

T7505

Synonym: NE-10064 Dihydrochloride

Target: Potassium Channel

TAS-103 dihydrochloride

T7309

Synonym: TAS-103 (dihydrochloride),BMS-247615 dihydrochloride

Target: Topoisomerase

Vatalanib dihydrochloride

T6720

Synonym: CGP-797870 dihydrochloride,ZK-222584 dihydrochloride,Vatalanib 2HCl,PTK787 dihydrochloride,Vatalanib (PTK787) 2HCl,CGP-79787 dihydrochloride

Target: Apoptosis, VEGFR, PDGFR

Veliparib dihydrochloride

T2105

Synonym: ABT-888 dihydrochloride

Target: PARP, Autophagy

CP-31398 dihydrochloride

T21648

Synonym: CP 31398 dihydrochloride

Target: p53

Surfen dihydrochloride

T26240

Synonym: Aminokinuride dihydrochloride,Aminoquinuride dihydrochloride,NSC-12155,Aminokinuride 2HCl,Aminoquinuride 2HCl

Target: FGFR, Antiviral, Antibiotic

Banoxantrone dihydrochloride

T10459

Synonym: AQ4N dihydrochloride,AZD1689 2HCl

Target: NOS

PD 168568 dihydrochloride

T12383

Synonym: PD 168568 (dihydrochloride)

Target: Dopamine Receptor

Canertinib dihydrochloride

T2501

Synonym: CI-1033 dihydrochloride,PD-183805 dihydrochloride,Canertinib

Target: EGFR

GSK3368715 dihydrochloride

T11500L

Synonym: EPZ019997 dihydrochloride,GSK3368715 2HCl,EPZ019997 2HCl

Target: Histone Methyltransferase

Ceritinib dihydrochloride

T1791L

Synonym: LDK378 dihydrochloride

Target: IGF-1R, ALK

Mirodenafil dihydrochloride

TQ0126

Synonym: SK-3530 dihydrochloride

Target: PDE

(1E)-CFI-400437 dihydrochloride

T22288

Synonym: CFI-400437 dihydrochloride

Target: PLK

Pentamidine dihydrochloride

T23132

Synonym: MP-601205 dihydrochloride

Target: Phosphatase, Antibacterial, Antibiotic, Parasite, Antifungal

Daclatasvir dihydrochloride

T1786

Synonym: BMS-790052 dihydrochloride

Target: HCV Protease

4-Aminobenzamidine dihydrochloride

T60248

Synonym: p-Aminobenzamidine dihydrochloride

Target: Serine Protease

Hematoporphyrin dihydrochloride

T3213

Synonym: Hematoporphyrin IX dihydrochloride

Target: Apoptosis, Others, Endogenous Metabolite

L-Lysyl-L-lysine dihydrochloride

T61156

Synonym: Lysyllysine dihydrochloride

Target: Others

Talipexole dihydrochloride

T14490

Synonym: Domnin,B-HT 920 dihydrochloride

Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor

MAO-IN-M30 dihydrochloride

T38034

Synonym: M 30 dihydrochloride

Target: Monoamine Oxidase

BRL-15572 dihydrochloride

T6423

Synonym: BRL 15573 dihydrochloride

Target: 5-HT Receptor

Eravacycline dihydrochloride

T11227L

Synonym: TP-434-046,TP-434 dihydrochloride

Target: Antibacterial

H-1152 dihydrochloride

T35328

Synonym: H-1152 2HCl,H-1152 dihydrochloride

Target: ROCK

Copanlisib dihydrochloride

T14998

Synonym: BAY 80-6946 dihydrochloride

Target: Apoptosis, PI3K, mTOR

Prexasertib dihydrochloride

T4327

Synonym: LY2606368 (dihydrochloride),Prexasertib HCl,LY2606368

Target: Apoptosis, Chk, S6 Kinase

Protein kinase inhibitor H-7 dihydrochloride

T22831

Synonym: H-7 dihydrochloride

Target: PKC

Philanthotoxin 74 dihydrochloride

T16524

Synonym: PhTx-74 HCl,PhTx 74 dihydrochloride

Target: GluR, iGluR

Mibefradil dihydrochloride

T12032

Synonym: Ro 40-5967 (dihydrochloride)

Target: Calcium Channel

Meclizine dihydrochloride

T1110

Synonym: Meclozine dihydrochloride,NSC28728,Meclizine 2HCl

Target: Apoptosis, Histamine Receptor

Dorsomorphin dihydrochloride

T6146

Synonym: BML-275 2HCl,Compound C dihydrochloride,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride

Target: AMPK, Autophagy, TGF-beta/Smad

Latrepirdine dihydrochloride

T6562

Synonym: Dimebolin dihydrochloride,Latrepirdine,Latrepirdine 2HCl,Dimebolin

Target: Beta Amyloid, 5-HT Receptor, Adrenergic Receptor, GluR, Autophagy, Histamine Receptor

カタログ番号	製品名	別名	ターゲット
T4754	Pyridoxylamine dihydrochloride	Pyridorin,Pyridoxamine dihydrochloride	Others , Endogenous Metabolite
	Pyridoxylamine dihydrochloride (Pyridorin) is a hydrochloride salt of one form of vitamin B6.		Others , Endogenous Metabolite
T2920	Berbamine dihydrochloride	Berbamine,dihydrochloride	Apoptosis , NF-κB , Bcr-Abl , Autophagy
	Berbamine dihydrochloride (Berbamine), a natural compound derived from the Berberis amurensis plant, has been shown to exhibit antitumor activity in several Ys.		Apoptosis , NF-κB , Bcr-Abl , Autophagy
TN1012L	Febrifugine dihydrochloride	ISF-2123,Propyldazine hydrochloride,Atensil,(+)-Febrifugine dihydrochloride,Pildralazine dihydrochloride	Parasite
	Febrifugine dihydrochloride (Propyldazine hydrochloride) is a biochemical with therapeutic activity regarding malaria, cancer, fibrosis and inflammatory diseases.		Parasite
T0810	Ethambutol dihydrochloride	Ethambutol 2HCl,Emb dihydrochloride,CL40881	Antibacterial , Antibiotic , Antifungal
	Ethambutol dihydrochloride (CL40881) is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.		Antibacterial , Antibiotic , Antifungal
T7117	Sapropterin dihydrochloride	Sapropterin Hydrochloride,6R-Tetrahydro-L-biopterin dihydrochloride,6R-BH4 dihydrochloride	Hydroxylase
	Sapropterin dihydrochloride (6R-BH4 dihydrochloride) is phenylalanine hydroxylase agonist that is approved for the treatment of BH4 responsive PKU.		Hydroxylase
T2219	Puromycin dihydrochloride	CL13900 dihydrochloride,Puromycin 2HCl	ribosome , DNA/RNA Synthesis , Antibacterial , Antibiotic
	Puromycin dihydrochloride (CL13900 dihydrochloride) is a cinnamamide adenosine antibiotic and an inhibitor of protein synthesis. Puromycin dihydrochloride inhibits protein synthesis by binding to RNA and has antitumor an...		ribosome , DNA/RNA Synthesis , Antibacterial , Antibiotic
T4895	Pentane-1,5-diamine dihydrochloride	5-diamine dihydrochloride,Cadaverine dihydrochloride,Pentane-1	Endogenous Metabolite
	Pentane-1,5-diamine dihydrochloride (Cadaverine dihydrochloride), dihydrochloride salt of cadaverine (a diamine), is a biogenic amine		Endogenous Metabolite
T4899	L-Histidinol dihydrochloride		Endogenous Metabolite
	L-Histidinol dihydrochloride is a precursor of histamine and a reversible inhibitor of protein synthesis.		Endogenous Metabolite
T8790	1-Methylhistamine dihydrochloride		Endogenous Metabolite
	1-Methylhistamine dihydrochloride is a major metabolite of histamine by histamine N-methyltransferase in the pathway of histidine metabolism. It has been used as a biomarker of histaminergic system activity in the brains...		Endogenous Metabolite
T4940	3-Methylhistamine dihydrochloride		Others , Endogenous Metabolite
	N tau-methylhistamine is one of the histamine metabolites. N tau-methylhistamine in plasma and urine is a good parameter for histamine release, and the determination of this histamine metabolite is generally less hampere...		Others , Endogenous Metabolite
T19466	N8-Acetylspermidine dihydrochloride		Endogenous Metabolite
	N8-Acetylspermidine dihydrochloride is a polyamine.		Endogenous Metabolite
T4333	Quinine dihydrochloride	Quinine bimuriate	Others
	Quinine dihydrochloride (Quinine bimuriate) is a primary alkaloid of various species of Cinchona (Rubiaceae). It is also an antimalarial and muscle relaxant (skeletal).		Others
T6534	Histamine dihydrochloride	peremin,Ceplene,Histamine 2HCl	Endogenous Metabolite , Histamine Receptor
	Histamine dihydrochloride (Ceplene) is dihydrochloride form of Histamine. Histamine is an organic nitrogen compound which is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodila...		Endogenous Metabolite , Histamine Receptor
T0788	Spectinomycin dihydrochloride	Spectinomycin 2HCl,Actinospectacin	ribosome , Antibacterial , Antibiotic
	Spectinomycin dihydrochloride (Actinospectacin) is an antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea.		ribosome , Antibacterial , Antibiotic
TQ0109	Cephaeline dihydrochloride	(-)-Cephaeline dihydrochloride,NSC 32944	P450
	(-)-Cephaeline (dihydrochloride) is an enantiomer of Cephaeline. Cephaeline is a selective CYP2D6 inhibitor (IC50: 121 μM).		P450
T19394	L-hydroxylysine dihydrochloride	(2S,5R)-5-Hydroxylysine dihydrochloride	Others
	L-hydroxylysine dihydrochloride , is formed by posttranslational hydroxylation of some lysine residues. It is an amino acid, is exclusive to collagen protein.		Others
T38541	Chitobiose dihydrochloride
	Chitobiose dihydrochloride is a chitosan oligosaccharide consisting of β-1,4-linked glucosamine units.
T22213	1,4-Diaminobutane Dihydrochloride		Others
	1,4-Diaminobutane dihydrochloride, an endogenous metabolite, acts as an indicator of pollution-induced stress in higher plants: barley and rape stressed with Cr(III) or Cr(VI). In addition, 1,4-Diaminobutane dihydrochlor...		Others
T60789	L-Cystine dihydrochloride
	L-Cystine dihydrochloride is a sulfur-containing precursor of glutathione (GSH) synthesis. The homeostasis of L-Cystine dihydrochloride is important for GSH functions. L-Cystine can be used as a cell culture ingredient [...
TN7229	Baihuaqianhuoside	Praeroside	Others
	Baihuaqianhuoside (Praeroside) is a coumarin glycoside. Baihuaqianhuoside can be isolated from the roots of Passiflora and Hindenia solanacea and was first isolated from P. japonicum. Baihuaqianhuoside has anti-inflammat...		Others