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ターゲット

COX

980

阻害剤

163

天然化合物

306

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T11660	Insulin levels modulator		COX
	Insulin level regulators can be used to treat diabetes.		COX
T21865	BC 11-38		PDE
	BC 11-38 is a potent, selective PDE biodepressant which is mainly effective against PDE11 (IC50 : 0.28 μM).		PDE
T3174	Taprenepag	CP-544326	Prostaglandin Receptor
	Taprenepag (CP-544326) (CP-544326) is a potent and selective prostaglandin E2 receptor agonist (EC50 = 2.8 nM). Taprenepag has been used in trials studying the treatment of Ocular Hypertension and Glaucoma, Open-Angle.		Prostaglandin Receptor
T23550	YM-750	YM 750	Acyltransferase
	YM-750 is a potent inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), with an IC50 value of 0.18 μM. ACAT is an enzyme that catalyzes the conversion of cholesterol and long-chain fatty-acyl-coenzyme A into cholest...		Acyltransferase
T4473	Ibiglustat	Venglustat,SAR402671,GZ402671	Transferase
	Ibiglustat (GZ402671) is a potent and selective Glucosylceramide synthase inhibitor and ceramide glucosyltransferase inhibitor. Ibiglustat blocks the formation of glucosylceramide (GL-1), a key intermediate in the synthe...		Transferase
T7943	Fluphenazine decanoate		Dopamine Receptor
	Fluphenazine decanoate is dopamine D2 receptor blocke,and is a long-acting phenothiazine neuroleptic that used to treat schizophrenia.		Dopamine Receptor
T7180	Sultopride hydrochloride	LIN-1418 hydrochloride	Dopamine Receptor
	Sultopride hydrochloride (LIN-1418 hydrochloride) is a selective dopamine D2 and D3 receptor antagonist.		Dopamine Receptor
T8818	TC-G 1005		GPCR19
	TC-G 1005 is a potent and selective GPBA agonist (EC50 :0.72 nM; hTGR5). Selective for TGR5 over FXR (farnesoid X receptor). Increases plasma GLP-1 levels and reduces blood glucose in mice. Orally available.		GPCR19
T1871	GBR 12935 dihydrochloride	GBR12935,GBR-12935,GBR 12935	Dopamine Receptor
	GBR 12935 dihydrochloride (GBR 12935) can induce the increase of the extracellular levels of dopamine to basal levels.		Dopamine Receptor
T4058	R-IMPP		Others , Serine/threonin kinase
	R-IMPP is an inhibitor of PCSK9 translation. R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted transferrin.		Others , Serine/threonin kinase
T14075	A-802715		IL Receptor
	A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases the formation and blood levels of anti-inflammatory substances such as i...		IL Receptor
T4582	Xanthanol	NSC 4038	Others
	Xanthanol(NSC 4038) is used to test the levels of urea in the bloodstream.		Others
T30531L	BMS-561392 Formic acid	BMS-561392 Formic acid(611227-74-8 Free base)	MMP
	BMS-561392 Formic acid is a selective inhibitor of TACE and reduces TNFalpha levels.		MMP
T3631	PF-8380		PDE
	PF-8380 is an effective and orally available autotaxin inhibitor (IC50: 2.8 nM, in isolated enzyme assay; 101 nM, in the human whole blood). It modulates lysophosphatidic acid (LPA) levels in vivo/vitro by directly inhib...		PDE
T39989L	JQKD82 trihydrochloride		Histone Demethylase
	JQKD82 trihydrochloride, a cell-permeable and selective inhibitor of KDM5, enhances H3K4me3 levels and is utilized in multiple myeloma research.		Histone Demethylase
T15549	Icosabutate		Others
	Icosabutate is a structurally engineered and orally active ω-3 polyunsaturated fatty acid. Icosabutate is well tolerated, and efficacious in lowering non-high-density lipoprotein cholesterol (non-HDL-C) levels in persist...		Others
T64345	4-(Dimethylamino)phenol		Others
	4-(Dimethylamino)phenol enhances extracellular lactate dehydrogenase (LDH) levels without significant effects on gluconeogenesis. Only when the membrane becomes permeable to LDH does 4-(Dimethylamino)phenol reduce ATP co...		Others
T60164	UNC7467		Others
	UNC7467 is a potent IP6K inhibitor with values of 4.9, 8.9 and 1320 nM for IP6K2, IP6K1 and IP6K6, respectively. UNC7467 reduces levels of inositol pyrophosphates without significantly perturbing levels of other inositol...		Others
T36536	SH-42
	SH-42 is an inhibitor of 24-dehydrocholesterol reductase (DHCR24; IC50= 4.2 nM).1It increases serum levels of desmosterol , the immediate precursor of cholesterol in the Bloch pathway, in mice when administered at a dos...
T1928	Anacetrapib	MK-0859	CETP
	Anacetrapib (MK-0859) (MK0859) is an effective, specific, reversible rhCETP and mutant CETP(C13S) inhibitor (IC50: 7.9 nM and 11.8 nM). Anacetrapib reduces the transfer of cholesteryl ester from HDL to LDL and/or VLDL th...		CETP
T13919	Terbufibrol		Others
	Terbufibrol reduces the levels of serum total cholesterol in normal and hypercholesterolemic male rats.		Others
T26278	Tildacerfont		CRFR
	Tildacerfont is an antagonist of CRF1 and reduces the levels of adrenocorticotropic hormone and adrenal androgen. Tildacerfont can be used in studies about congenital adrenal hyperplasia.		CRFR
T10492	BD-AcAc 2	Ketone Ester	Reactive Oxygen Species
			Reactive Oxygen Species
T4512	Magnesium glycinate	magnesium 2-aminoacetate,Magnesium diglycinate	Others
	Magnesium glycinate (magnesium 2-aminoacetate) is a supplement that boost magnesium levels in people with a deficiency of the mineral. Magnesium is a vital nutrient for regulating many body processes, including muscle an...		Others
T50041	N-(4-methoxyphenyl)prop-2-enamide	N-(4-Methoxyphenyl)acrylamide	Others
	N-(4-methoxyphenyl)prop-2-enamide (N-(4-Methoxyphenyl)acrylamide) is an acrylamide analog used as a molecular structural unit. It inhibits the enzyme acetylcholinesterase, increasing acetylcholine levels in the synaptic ...		Others
T65554	Cholesterol-absorption inhibitor Intermediate 2		Others
	cholesterol-absorption inhibitor Intermediate 2 is a potent and orally active cholesterol absorption inhibitor that reduces blood cholesterol levels.		Others
T60033	SBI993		Others
	SBI993 is an analog of SBI-477 and can be used as a biomarker to confirm the expected action of MondoA target gene expression in vivo. SBI993 reduces muscle TAG levels and hepatic steatosis.		Others
T8646	URB937		FAAH
	URB937 is an inhibitor of FAAH and increases anandamide levels(IC50 : 26.8 nM).		FAAH
T36926L	Neuropeptide SF (human) aceate		Others
	Neuropeptide SF (human) aceate is a neuropeptide that augmented paraventricular CRH release and increased ACTH and corticosterone levels in the plasma.		Others
T18929	Bromobimane	Monobromobimane	Autophagy
	Bromobimane (Monobromobimane) is a non-fluorescent substance, but reacts with thiols to produce a fluorescent product.Bromobimane is used as a probe, often in clinical medicine, to test for sulfide levels in blood.		Autophagy
T15251	Etebenecid	Urelim	Others
	Etebenecid (Urelim) is uricosuric agents, which lower uric acid levels in the body by increasing the elimination of uric acid by the kidneys. It also inhibits penicillin tubular secretion.		Others
T0880	Bronopol	BNPK,BNPD	Antibacterial
	Bronopol (BNPD) is an antimicrobial agent with low mammalian toxicity (at in-use levels) and high activity against bacteria, especially the troublesome Gram-negative species.		Antibacterial
T50029	2-((2,2-Dibenzylhydrazineylidene)methyl)pyridine	2-[(1E)-(dibenzylhydrazin-1-ylidene)methyl]pyridine	Others
	2-((2,2-Dibenzylhydrazineylidene)methyl)pyridine (2-[(1E)-(dibenzylhydrazin-1-ylidene)methyl]pyridine) is a heterocyclic compound. It inhibits monoamine oxidase, resulting in elevated monoamine levels in the body. It can...		Others
T24833	ZINC69391	ZINC-69391,ZINC 69391,N'-(4,6-dimethylpyrimidin-2-yl)-N-[2-(trifluoromethyl)phenyl]guanidine,CysHHC10 acetate(1408311-03-4 free base)	Apoptosis , Rho
	ZINC69391 (CysHHC10 acetate(1408311-03-4 free base)) is a selective inhibitor of Rac1 with antiproliferative and antimetastatic effects. ZINC69391 interferes with the interaction of Rac1 with Dock180, reduces Rac1-GTP le...		Apoptosis , Rho
T16342	KL1333	NQO1 activator 1	NADPH , Mitochondrial Metabolism
	KL1333 (NQO1 activator 1) enhances energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. Elevated NAD+ levels trigger the activation of SIRT1 and AMPK, and subsequently activates PGC-1α. NQO1 activator 1 ...		NADPH , Mitochondrial Metabolism
T31101	CRT0273750	CRT 0273750,CRT-0273750	PDE
	CRT0273750 regulates plasma LPA levels and is suitable for in vivo studies. CRT0273750 is an autotaxin (ATX) inhibitor with IC50 of 0.014 μM.		PDE
T8547	DCBA		Drug Metabolite
	DCBA, an endogenous metabolite of the insect repellent N-N-diethyl-meta-toluamide (DEET), is utilized to evaluate DEET exposure through its concentration levels in urine.		Drug Metabolite
T67832	ALDH2 modulator 1		Dehydrogenase
	ALDH2 modulator 1 is a potent and orally active modulator of acetaldehyde dehydrogenase-2 (ALDH2), which reduces blood alcohol levels in mice.		Dehydrogenase
T13591	Calcium polystyrene sulfonate	Poly(styrenesulfonic acid) calcium salt	Others
	Calcium polystyrene sulfonate (Poly(styrenesulfonic acid) calcium salt) is an ion-exchange resin. Calcium polystyrene sulfonate reduces blood levels of potassium and can be used for research on the treatment of hyperkale...		Others
T16757	Risdiplam	RO7034067,RG7916	DNA/RNA Synthesis
	Risdiplam (RO7034067) (RG7916) is orally administered. Risdiplam is a centrally and peripherally distributed SMN2 pre-mRNA splicing modifier which increases survival motor neuron (SMN) protein levels[1].		DNA/RNA Synthesis
T36454	1-Stearoyl-rac-glycerol
	1-Stearoyl-rac-glycerol is a monoacylglycerol that contains stearic acid at the sn-1 position. 1-Stearoyl-rac-glycerol levels are decreased in tumor tissue in a mouse model of azoxymethane-induced colorectal carcinogenes...
T7407	Thyrotropin-Releasing Hormone (TRH), Free Acid	TRH-OH	Others
	Thyrotropin-Releasing Hormone (TRH), Free Acid (TRH-OH) (TRH-OH) causes a variety of thyroidal and non-thyroidal effects, the best known being the feedback regulation of thyroid hormone levels.		Others
T8706	STAMBP-IN-1		Others
	STAMBP-IN-1 is a novel selective antagonist of deubiquitinase STAM-binding protein (STAMBP), decreasing NALP7 protein levels and suppressing IL-1β release after TLR agonism.		Others
T1416	Zidovudine	Azidothymidine,NSC 602670,ZDV,AZT	HIV Protease , Reverse Transcriptase , Telomerase , CRISPR/Cas9
	Zidovudine (ZDV) is a synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the inhibition of DNA replication and cell death. This age...
T67778	DCeMM1		Molecular Glues
	dCeMM1 is a RBM39 glue degrader. dCeMM1 can re-direct the activity of the CRL4DCAF15 ligase. dCeMM1 can decrease the expression levels of RBM39 in WT KBM7 cells.		Molecular Glues
T1423	3-Methylsalicylic acid	Hydroxytoluic acid,o-Cresotic acid	COX
	3-Methylsalicylic acid (o-Cresotic acid) is a long-acting salicylate derivative with antilipidemic properties. Hydroxytoluic acid has been shown to lower plasma free fatty acid and cholesterol levels.		COX
T17011	TCH-165		Proteasome
	TCH-165 is a small molecule modulator of proteasome assembly, resulting in an increase in 20S levels. The increase in the level of free 20S corresponds to enhanced proteolysis of IDPs.		Proteasome
T2121	SW033291		Dehydrogenase
	SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues.		Dehydrogenase
T4022	QS11	QS 11	GTPase
	QS11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. Modulates ARF-GTP levels and synergizes with the Wnt/β-catenin signaling pathway to upregulate β-catenin nuclear translocation. Also r...		GTPase
T74794	USP28-IN-4		DUB
	USP28-IN-4 is a potent USP28 inhibitor with an IC50 value of 0.04 μM against USP28. USP28-IN-4 exhibits anticancer activity and inhibits USP2, USP7, USP8, USP9x, UCHL3 and UCHL5. USP28-IN-4 is cytotoxic to human colorect...		DUB

Compounds

Insulin levels modulator

Target: Prostaglandin Receptor

YM-750

T23550

Synonym: YM 750

Target: Acyltransferase

Ibiglustat

T4473

Synonym: Venglustat,SAR402671,GZ402671

Target: Transferase

Fluphenazine decanoate

T7943

Synonym:

Target: Dopamine Receptor

Sultopride hydrochloride

T7180

Synonym: LIN-1418 hydrochloride

Target: Dopamine Receptor

GBR 12935 dihydrochloride

T1871

Synonym: GBR12935,GBR-12935,GBR 12935

Target: Dopamine Receptor

R-IMPP

T4058

Synonym:

Target: Others, Serine/threonin kinase

BMS-561392 Formic acid

T30531L

Synonym: BMS-561392 Formic acid(611227-74-8 Free base)

JQKD82 trihydrochloride

T39989L

Synonym:

Target: Histone Demethylase

4-(Dimethylamino)phenol

Synonym: Ketone Ester

Target: Reactive Oxygen Species

Magnesium glycinate

T4512

Synonym: magnesium 2-aminoacetate,Magnesium diglycinate

Target: Others

N-(4-methoxyphenyl)prop-2-enamide

T50041

Synonym: N-(4-Methoxyphenyl)acrylamide

Target: Others

cholesterol-absorption inhibitor Intermediate 2

Neuropeptide SF (human) aceate

Synonym: Monobromobimane

Target: Antibacterial

2-((2,2-Dibenzylhydrazineylidene)methyl)pyridine

T50029

Synonym: 2-[(1E)-(dibenzylhydrazin-1-ylidene)methyl]pyridine

Target: Others

ZINC69391

T24833

Synonym: ZINC-69391,ZINC 69391,N'-(4,6-dimethylpyrimidin-2-yl)-N-[2-(trifluoromethyl)phenyl]guanidine,CysHHC10 acetate(1408311-03-4 free base)

Target: Apoptosis, Rho

KL1333

T16342

Synonym: NQO1 activator 1

Target: NADPH, Mitochondrial Metabolism

CRT0273750

T31101

Synonym: CRT 0273750,CRT-0273750

Target: Drug Metabolite

ALDH2 modulator 1

T67832

Synonym:

Target: Dehydrogenase

Calcium polystyrene sulfonate

T13591

Synonym: Poly(styrenesulfonic acid) calcium salt

Target: Others

Risdiplam

T16757

Synonym: RO7034067,RG7916

Target: DNA/RNA Synthesis

1-Stearoyl-rac-glycerol

T36454

Synonym:

Target:

Thyrotropin-Releasing Hormone (TRH), Free Acid

Synonym: Azidothymidine,NSC 602670,ZDV,AZT

Target: HIV Protease, Reverse Transcriptase, Telomerase, CRISPR/Cas9

dCeMM1

T67778

Synonym:

Target: Molecular Glues

3-Methylsalicylic acid

T1423

Synonym: Hydroxytoluic acid,o-Cresotic acid

Target: Dehydrogenase

カタログ番号	製品名	別名	ターゲット
TQ0218	Deoxyandrographolide	14-deoxyandrographolide	IL Receptor , TNF
			IL Receptor , TNF
T5S2083	Puerarin 6''-O-Xyloside		Apoptosis , Caspase
	Puerarin 6''-O-xyloside possesses significant anti-osteoporotic activity on ovariectomy mice, it has significant antitumour activities, the mechanisms are related to increased levels of caspase-3, caspase-7, caspase-9 an...		Apoptosis , Caspase
T0419	Testosterone propionate		Others , Androgen Receptor , Transferase
	Testosterone Propionate is a short acting oil-based injectable formulation of testosterone. Testosterone inhibits gonadotropin secretion from the pituitary gland and ablates estrogen production in the ovaries, thereby de...		Others , Androgen Receptor , Transferase
T2S0410	Euphorbia factor L1	Euphorbiasteroid	Apoptosis , P-gp
	Euphorbia factor L1 (Euphorbiasteroid) can reduce Bcl-2, PI3K, AKT, and mTOR protein and mRNA levels, and up-regulate caspase-9 and caspase-3 protein levels. It induces autophagy and has anti-cancer, anti-adipogenic, ant...		Apoptosis , P-gp
T4588	Glycochenodeoxycholic Acid	Glycine chenodeoxycholate,Chenodeoxycholylglycine,GCDCA,Glycochenodeoxycholate,Lithocholylglycine	Apoptosis , Endogenous Metabolite
	Glycochenodeoxycholic Acid (Lithocholylglycine) is a glycine conjugate of lithocholic acid, a bile acid. It is increased in livers of mice that are fed diets supplemented with ursadeoxycholic acid. Glycolithocholic acid ...		Apoptosis , Endogenous Metabolite
T5251	Phenylpyruvic acid	2-Oxo-3-phenylpropanoic acid,3-Phenylpyruvic acid	Others , Endogenous Metabolite
	Phenylpyruvic acid (3-Phenylpyruvic acid) is a keto-acid that is an intermediate or catabolic byproduct of phenylalanine metabolism. It has a slight honey-like odor. Levels of phenylpyruvate are normally very low in bloo...		Others , Endogenous Metabolite
T4752	1-Aminocyclopropane-1-carboxylic acid	1-Aminocyclopropanecarboxylic acid,1-Amino-1-carboxycyclopropane,ACC	Endogenous Metabolite , NMDAR
	1-Aminocyclopropane-1-carboxylic acid (ACC) is an intermediate in the synthesis of ethylene, the plant hormone responsible for biological processes ranging from seed germination to organ senescence. It is a small molecul...		Endogenous Metabolite , NMDAR
TL0013	Heraclenin		Anti-infection , Immunology/Inflammation related
	Heraclenin has anticoagulant, and anti-inflammatory activities, it also has mutagenicity in Chlamydomonas reinhardii. Heraclenin can induce apoptosis in Jurkat leukemia cells, it has a strong clastogenic effect . (+)-Her...		Anti-infection , Immunology/Inflammation related
TQ0024	3-Hydroxyglutaric acid		Endogenous Metabolite
	3-Hydroxyglutaric acid is one of several metabolites produced when insufficient levels of GCDH are available. It is used as a biomarker of GCDH deficiency.		Endogenous Metabolite
TWO2727	Propane-1,2,3-triyl tripalmitate	Palmitic Triglyceride,Tripalmitin,Tripalmitoylglycerol,Glycerol Tripalmitate	Others , Endogenous Metabolite
	Propane-1,2,3-triyl tripalmitate (Glycerol Tripalmitate) is a triacylglycerol found in dietary fats. Tripalmitin increases body weight and plasma LDL levels and reduces hepatic LDL receptor mRNA levels in hamsters fed a ...		Others , Endogenous Metabolite
T3S1701	Dihydrocurcumin		PPAR , Fatty Acid Synthase
	Dihydrocurcumin is the main metabolite of curcumin, which can reduce fat accumulation and oxidative stress response. Dihydrocurcumin can regulate the mRNA and protein expression levels of SREBP-1C, PNPLA3 and PPARα, incr...		PPAR , Fatty Acid Synthase
T4810	Pyrocatechuic acid	3-Hydroxysalicylic acid,O-Pyrocatechuic acid,Catecholcarboxylic acid,NSC 27435,2,3-Dihydroxybenzoic acid	Others , Endogenous Metabolite
	Pyrocatechuic acid (Catecholcarboxylic acid), a normal human benzoic acid metabolite found in plasma, has increased levels after aspirin ingestion.		Others , Endogenous Metabolite
TCS1772	Dehydroabietic acid	Dehydroabietate	Antifection
	1. Dehydroabietic acid (Dehydroabietate) (DAA) is an EBV-EA activation inhibitor. 2. DAA is a useful food-derived compound for treating obesity-related diseases, by decreasing plasma glucose, insulin levels, plasma trigl...		Antifection
T7344	SDMA	NG,NG'-Dimethyl-L-arginine,Symmetric dimethylarginine	Endogenous Metabolite
	SDMA (Symmetric dimethylarginine) is the most potent endogenous inhibitor of nitric oxide synthase (NOS), with higher levels in patients with end-stage renal disease (ESRD).		Endogenous Metabolite
T5229	DL -3,4-Dihydroxymandelic acid		Others
	3,4-Dihydroxymandelic acid is a minor metabolite of norepinephrine in humans. Patients with neuroblastoma experience elevated levels of 3,4-Dihydroxymandelic acid.		Others
T5544	2-Furoic acid	Furan-2-carboxylic acid	Anti-infection , ATP Citrate Lyase , Endogenous Metabolite , Acyltransferase
	2-Furoic acid (Furan-2-carboxylic acid) 2-Furoic acid can reduce serum cholesterol and triglyceride levels and has anti-lipidemic effects.
TN1058	Pelargonidin chloride		NOS , Reactive Oxygen Species , Nrf2 , NO Synthase
	Pelargonidin chloride shows protective effect against CTN-induced oxidative stress in HepG2 cells and up-regulated the activity of detoxification enzyme levels through Keap1/Nrf2 signaling pathway.		NOS , Reactive Oxygen Species , Nrf2 , NO Synthase
T41122	1,3-Dihydroxyacetone		Endogenous Metabolite
	1,3-Dihydroxyacetone is the main active ingredient in sunscreen tanning skin care preparations, an important precursor for the synthesis of a variety of fine chemicals, and a food additive that can be produced on an indu...		Endogenous Metabolite
T1400	Demeclocycline hydrochloride	Declomycin,Clortetrin,Detravis,Demeclocycline HCl	ribosome , Antibacterial , Antibiotic
	Demeclocycline hydrochloride (Declomycin) is a TETRACYCLINE analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than TETRACYCLINE, it maintains effective blood levels for longer periods of time.		ribosome , Antibacterial , Antibiotic
T5219	L-Alloisoleucine	L-allo-Isoleucine,(3R)-LS-Isoleucine,L(+)-Alloisoleucine	Others , Endogenous Metabolite
	L-Alloisoleucine (L-allo-Isoleucine) is a branched chain amino acid and is a stereoisomer of L-isoleucine. It is a common constituent of human plasma (albeit at low levels). L-alloisoleucine is produced as a byproduct of...		Others , Endogenous Metabolite
TN6778	Umbelliprenin	7-[[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrienyl]oxy]-2H-1-benzopyran-2-oneUmbelliprenin	IL Receptor
	Umbelliprenin (7-[[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrienyl]oxy]-2H-1-benzopyran-2-oneUmbelliprenin) alleviated neuropathic pain, and decreased serum IL-6 levels and oxidative stress.		IL Receptor
TQ0193	N2,N2-Dimethylguanosine		Endogenous Metabolite
	N2,N2-Dimethylguanosine is an urinary nucleoside. The mean levels of urinary N2,N2-Dimethylguanosine in patients with colorectal cancer are significantly higher than those in patients with intestinal villous adenoma or h...		Endogenous Metabolite
T4S1796	Heterophyllin B		PI3K
	Heterophyllin B effectively suppresses the adhesion and invasion of the human esophageal carcinoma cells by mediating the PI3K/AKT/β-catenin pathways and regulating the expression levels of adhesion- and invasion-associa...		PI3K
T3895	Polyphyllin I		Apoptosis , Akt , JNK , PDK , mTOR , Autophagy
	Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C, and cleaved-caspase-3 levels. Polyphyllin D ha...		Apoptosis , Akt , JNK , PDK , mTOR , Autophagy
T7548	1-Methylguanosine	N1-Methylguanosine	Endogenous Metabolite
	1-Methylguanosine (N1-Methylguanosine) is a methylated nucleoside. It is known that some modified, especially methylated, nucleosides originating from RNA degradation are excreted in abnormal levels in the urine of patie...		Endogenous Metabolite
T0063	L-Isoleucine	isoleucine,Ile	Amino Acids and Derivatives , Endogenous Metabolite
	L-Isoleucine (Ile) is an essential branched-chain aliphatic amino acid found in many proteins. It is an isomer of LEUCINE. It is important in hemoglobin synthesis and regulation of blood sugar and energy levels.		Amino Acids and Derivatives , Endogenous Metabolite
T4720	6-Hydroxypyridin-2(1H)-one hydrochloride	2,6-Dihydroxypyridine hydrochloride	Others , Endogenous Metabolite
	6-Hydroxypyridin-2(1H)-one hydrochloride (2,6-Dihydroxypyridine hydrochloride) is used as a reagent to synthesize uridine phosphorylase inhibitors that increase Uridine (Urd) (U829910) levels. Uridine is a promising bioc...		Others , Endogenous Metabolite
T4944	Nervonic acid	cis-15-Tetracosenoic acid,Selacholeic acid	Endogenous Metabolite
	Nervonic acid (Selacholeic acid) is a long chain unsaturated fatty acid that is enriched in sphingomyelin. It consists of choline, sphingosine, phosphoric acid, and fatty acid. Nervonic acid may enhance the brain functio...		Endogenous Metabolite
T3809	Liriope muscari baily saponins C		Others
	Liriope muscari baily saponins C has an anti-thrombotic activity due to down-regulation of the increased mRNA expression levels of TF and IL-6.		Others
T0507	L-Pyroglutamic acid	pidolic acid,L-pyroglutamate,5-Oxoproline	Others , Endogenous Metabolite
	L-Pyroglutamic acid (pidolic acid), a cyclized derivative of the L-GLUTAMIC ACID, can elevate blood levels. This function may be associated with problems of GLUTATHIONE or GLUTAMINE metabolism.		Others , Endogenous Metabolite
T2S1975	Ponicidin	Rubescensine B	Apoptosis , JAK , STAT
	Ponicidin (Rubescensine B) is a diterpenoid derived from Rabdosia rubescens. Ponicidin exhibits immunoregulatory, anti-inflammatory, anti-viral, and anti-cancer activity. Ponicidin induces apoptosis of gastric carcinoma ...		Apoptosis , JAK , STAT
T5290	(S)-2-Hydroxy-3-phenylpropanoic acid	L-(−)-3-Phenyllactic acid	Others , Endogenous Metabolite
	(S)-2-Hydroxy-3-phenylpropanoic acid (L-(−)-3-Phenyllactic acid) is a chiral aromatic compound involved in phenylalanine metabolism. It is likely produced from phenylpyruvate via the action of lactate dehydrogenase. The ...		Others , Endogenous Metabolite
T4S2157	Campesterol	(24R)-5-Ergosten-3β-ol	Endogenous Metabolite
	Campesterol ((24R)-5-Ergosten-3β-ol) is a plant sterol with cholesterol lowering and anticarcinogenic effects, it and other plant sterols often decrease LDL cholesterol levels overall. Campesterol has anti-inflammatory e...		Endogenous Metabolite
T6S2023	Harpagoside		Others , COX , NO Synthase
	1. Harpagoside has anti-inflammatory activity. 2. Harpagoside at 3 mM concentration, shows moderate inhibition of seed germination. 3. Harpagoside can inhibit lipopolysaccharide-induced mRNA levels and protein expression...		Others , COX , NO Synthase
T3876	Loureirin B		PAI-1 , ERK , Potassium Channel , JNK
	Loureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress TGF-β1-induced fibrosis, during which TGF-β1/Smad2/3 pathw...		PAI-1 , ERK , Potassium Channel , JNK
T13795	Nicotinamide riboside		Sirtuin
	Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities.		Sirtuin
T4918	DL-Glyceraldehyde	Glyceric aldehyde	Reductase
	DL-Glyceraldehyde (Glyceric aldehyde) is produced from the action of the enzyme glyceraldehyde dehydrogenase, which converts glycerol to glyceraldehyde using NADP as a cofactor. When present at sufficiently high levels, ...		Reductase
T5780	HYPOCRELLIN B		Apoptosis , Parasite , Antifungal
	HYPOCRELLIN B are photosensitive pigments isolated from Hypocrella bambusae Sacc. Hypocrellin B causes DNA strand breakage, induces apoptosis in ovarian cancer cells, and inhibits proliferation of Staphylococcus by incre...		Apoptosis , Parasite , Antifungal
TQ0298	Fagomine	D-Fagomine	ROS , glycosidase
			ROS , glycosidase
T4S0795	Berberrubine chloride	9-Berberoline Chloride,Beroline,Beroline Chloride,Berberrubine,9-Berberoline	IL Receptor
	1. Berberrubine chloride (9-Berberoline Chloride) has antitumor activity. 2. Berberrubine has antidiabetic activity. 3. Berberrubine dose-dependently inhibits IL-8 and MCP-1 protein levels in the media and mRNA expressio...		IL Receptor
T7050	Alpha-Tocopherolquinone	Metarene	Antioxidant
	During hypoxia in rats, levels of α-tocopherylquinon have been found to rise. alpha-Tocopherolquinone (Metarene) is reported to downregulate the respiratory activity of mitochondria. alpha-Tocopherolquinone has also disp...		Antioxidant
T4726	D-Glucose 6-phosphate sodium	G6P sodium salt,D-Glucose 6-phosphate sodium salt,Sodium Glucose-6-Phosphate	Others , Endogenous Metabolite
	In cells, D-Glucose 6-phosphate sodium (G6P) is generated when glucose is phosphorylated by hexokinase or glucokinase or by the conversion of glucose-1-phosphate by phosphoglucomutase during glycogenolysis. G6P lies at t...		Others , Endogenous Metabolite
T0518	Methacycline hydrochloride	Rondomycin,Methacycline HCl	ribosome , Antibacterial , Antibiotic
	Methacycline hydrochloride (Rondomycin) is a broad-spectrum semisynthetic antibiotic related to TETRACYCLINE but excreted more slowly and maintaining effective blood levels for a more extended period.		ribosome , Antibacterial , Antibiotic
T14853	Cabergoline	FCE-21336	Dopamine Receptor , 5-HT Receptor , Autophagy
	Cabergoline (FCE-21336) is an ergot derived-dopamine D2-like receptor agonist. It has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respectively).Cabergoline permits rapid and effective hormonal a...		Dopamine Receptor , 5-HT Receptor , Autophagy
T6S1302	Carnosol		Nrf2 , Endogenous Metabolite , S6 Kinase
	Carnosol is an Nrf2 activator, increasing Nrf2 levels and promoting heme oxygenase 1 (HMOX1) expression. It is a ribosomal S6 kinase (RSK2) inhibitor and can be used in gastric cancer-related research with an IC50 value ...		Nrf2 , Endogenous Metabolite , S6 Kinase
T3729	Ethyl gallate	Nipagallin A,Phyllemblin,gallic acid ethyl ester	MMP , NF-κB , Akt , Antibacterial
	Ethyl gallate (gallic acid ethyl ester) obviously decreases cell proliferation in MDA-MB-231 and MCF-7 cells in a dose- and time-dependent manner, exhibits cytotoxicity in a dose-dependent manner. Ethyl gallate can inhib...		MMP , NF-κB , Akt , Antibacterial
T0710	L-Cycloserine	Levcycloserine,Levcicloserina,(-)-Cycloserine,(S)-Cycloserine,Levcycloserinum,(S)-4-Amino-3-isoxazolidone	HIV Protease , GABA Receptor
	L-Cycloserine ((-)-Cycloserine) irreversibly inhibits GABA pyridoxal 5′-phosphate-dependent aminotransferase in E. coli, as well in the brains of various animals, results in increased levels of gamma-aminobutyric acid (G...		HIV Protease , GABA Receptor
T2P2919	(2S,3R,4S)-4-Hydroxyisoleucine	(4S)-4-Hydroxy-L-isoleucine,Hydroxyisoleucine	PI3K
	(2S,3R,4S)-4-Hydroxyisoleucine (Hydroxyisoleucine) from fenugreek (Trigonella foenum-graecum) seeds is a potential insulinotropic (anti-diabetic) and anti-obesity amino acid. HIL stimulates glucose-dependent insulin secr...		PI3K
T4744	5-HYDROXYINDOLE-3-ACETIC ACID	5-HIAA	Others , Endogenous Metabolite
	5-Hydroxyindole-3-acetic acid (5-HIAA) is a breakdown product of serotonin that is excreted in the urine. Serotonin and 5HIAA are produced in excess amounts by carcinoid tumors, and levels of these substances may be meas...		Others , Endogenous Metabolite
T5231	2-Methylsuccinic acid	Pyrotartaric Acid,Methylbutanedioic acid	Others , Endogenous Metabolite
	2-Methylsuccinic acid (Pyrotartaric Acid) is a normal metabolite found in human fluids. Increased urinary levels of 2-Methylsuccinic acid (Pyrotartaric Acid) (together with ethylmalonic acid) are the main biochemical mea...		Others , Endogenous Metabolite
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天然物製品

Deoxyandrographolide

TQ0218

Synonym: 14-deoxyandrographolide

Target: IL Receptor, TNF

Puerarin 6''-O-Xyloside

T5S2083

Synonym:

Target: Apoptosis, Caspase

Testosterone propionate

T0419

Synonym:

Target: Others, Androgen Receptor, Transferase

Euphorbia factor L1

T2S0410

Synonym: Euphorbiasteroid

Target: Apoptosis, P-gp

Glycochenodeoxycholic Acid

T4588

Synonym: Glycine chenodeoxycholate,Chenodeoxycholylglycine,GCDCA,Glycochenodeoxycholate,Lithocholylglycine

Target: Apoptosis, Endogenous Metabolite

Phenylpyruvic acid

T5251

Synonym: 2-Oxo-3-phenylpropanoic acid,3-Phenylpyruvic acid

Target: Others, Endogenous Metabolite

1-Aminocyclopropane-1-carboxylic acid

T4752

Synonym: 1-Aminocyclopropanecarboxylic acid,1-Amino-1-carboxycyclopropane,ACC

Target: Endogenous Metabolite, NMDAR

Heraclenin

TL0013

Synonym:

Target: Anti-infection, Immunology/Inflammation related

3-Hydroxyglutaric acid

TQ0024

Synonym:

Target: Endogenous Metabolite

Propane-1,2,3-triyl tripalmitate

TWO2727

Synonym: Palmitic Triglyceride,Tripalmitin,Tripalmitoylglycerol,Glycerol Tripalmitate

Target: Others, Endogenous Metabolite

Dihydrocurcumin

T3S1701

Synonym:

Target: PPAR, Fatty Acid Synthase

Pyrocatechuic acid

T4810

Synonym: 3-Hydroxysalicylic acid,O-Pyrocatechuic acid,Catecholcarboxylic acid,NSC 27435,2,3-Dihydroxybenzoic acid

Target: Others, Endogenous Metabolite

Dehydroabietic acid

TCS1772

Synonym: Dehydroabietate

Target: Antifection

SDMA

T7344

Synonym: NG,NG'-Dimethyl-L-arginine,Symmetric dimethylarginine

Target: Endogenous Metabolite

DL -3,4-Dihydroxymandelic acid

Synonym: Furan-2-carboxylic acid

Target: Anti-infection, ATP Citrate Lyase, Endogenous Metabolite, Acyltransferase

Pelargonidin chloride

TN1058

Synonym:

Target: NOS, Reactive Oxygen Species, Nrf2, NO Synthase

1,3-Dihydroxyacetone

T41122

Synonym:

Target: Endogenous Metabolite

Demeclocycline hydrochloride

T1400

Synonym: Declomycin,Clortetrin,Detravis,Demeclocycline HCl

Target: ribosome, Antibacterial, Antibiotic

L-Alloisoleucine

T5219

Synonym: L-allo-Isoleucine,(3R)-LS-Isoleucine,L(+)-Alloisoleucine

Target: Others, Endogenous Metabolite

Umbelliprenin

TN6778

Synonym: 7-[[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrienyl]oxy]-2H-1-benzopyran-2-oneUmbelliprenin

Target: IL Receptor

N2,N2-Dimethylguanosine

TQ0193

Synonym:

Target: Endogenous Metabolite

Target: Apoptosis, Akt, JNK, PDK, mTOR, Autophagy

1-Methylguanosine

T7548

Synonym: N1-Methylguanosine

Target: Endogenous Metabolite

L-Isoleucine

T0063

Synonym: isoleucine,Ile

Target: Amino Acids and Derivatives, Endogenous Metabolite

6-Hydroxypyridin-2(1H)-one hydrochloride

T4720

Synonym: 2,6-Dihydroxypyridine hydrochloride

Target: Others, Endogenous Metabolite

Nervonic acid

T4944

Synonym: cis-15-Tetracosenoic acid,Selacholeic acid

Target: Endogenous Metabolite

Liriope muscari baily saponins C

Synonym: pidolic acid,L-pyroglutamate,5-Oxoproline

Target: Others, Endogenous Metabolite

Ponicidin

T2S1975

Synonym: Rubescensine B

Target: Apoptosis, JAK, STAT

(S)-2-Hydroxy-3-phenylpropanoic acid

T5290

Synonym: L-(−)-3-Phenyllactic acid

Target: Others, Endogenous Metabolite

Campesterol

T4S2157

Synonym: (24R)-5-Ergosten-3β-ol

Target: Endogenous Metabolite

Harpagoside

T6S2023

Synonym:

Target: Others, COX, NO Synthase

Loureirin B

T3876

Synonym:

Target: PAI-1, ERK, Potassium Channel, JNK

Nicotinamide riboside

Synonym: Glyceric aldehyde

Target: Apoptosis, Parasite, Antifungal

Fagomine

TQ0298

Synonym: D-Fagomine

Target: ROS, glycosidase

Berberrubine chloride

T4S0795

Synonym: 9-Berberoline Chloride,Beroline,Beroline Chloride,Berberrubine,9-Berberoline

Target: IL Receptor

alpha-Tocopherolquinone

T7050

Synonym: Metarene

Target: Antioxidant

D-Glucose 6-phosphate sodium

T4726

Synonym: G6P sodium salt,D-Glucose 6-phosphate sodium salt,Sodium Glucose-6-Phosphate

Target: Others, Endogenous Metabolite

Methacycline hydrochloride

T0518

Synonym: Rondomycin,Methacycline HCl

Target: ribosome, Antibacterial, Antibiotic

Cabergoline

T14853

Synonym: FCE-21336

Target: Dopamine Receptor, 5-HT Receptor, Autophagy

Carnosol

T6S1302

Synonym:

Target: Nrf2, Endogenous Metabolite, S6 Kinase

Ethyl gallate

T3729

Synonym: Nipagallin A,Phyllemblin,gallic acid ethyl ester

Target: MMP, NF-κB, Akt, Antibacterial

L-Cycloserine

T0710

Synonym: Levcycloserine,Levcicloserina,(-)-Cycloserine,(S)-Cycloserine,Levcycloserinum,(S)-4-Amino-3-isoxazolidone

Target: HIV Protease, GABA Receptor

(2S,3R,4S)-4-Hydroxyisoleucine

T2P2919

Synonym: (4S)-4-Hydroxy-L-isoleucine,Hydroxyisoleucine

Target: PI3K

5-HYDROXYINDOLE-3-ACETIC ACID

T4744

Synonym: 5-HIAA

Target: Others, Endogenous Metabolite

2-Methylsuccinic acid

T5231

Synonym: Pyrotartaric Acid,Methylbutanedioic acid

Target: Others, Endogenous Metabolite

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-04310	Apolipoprotein A-IV/APOA4 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Apolipoprotein is genetically associated with the risk of Alzheimer's disease (AD). The APOA1, APOC3, and APOA4 genes are closely linked and located on human chromosome 11. There was a decreased trend for levels of APOA1...
TMPK-00369	HGF Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Hepatocyte growth factor (HGF) is an important component of the pathophysiology of IR, with increased levels in most common IR conditions, including obesity. HGF has a role in the metabolic flux of glucose in different i...
TMPY-03274	CXCL11 Protein, Human, Recombinant	Human	E. coli
	I-TAC, also known as CXCL11, is a small cytokine belonging to the CXC chemokine family. It is highly expressed in peripheral blood leukocytes, pancreas and liver, with moderate levels in thymus, spleen and lung and low e...
TMPY-04853	TSHR Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Thyroid-stimulating hormone (TSH) is secreted by the pituitary gland and promotes thyroid growth and function, with increased TSH levels typically associated with hypothyroidism. Immunohistochemical analysis revealed pre...
TMPJ-01204	TPSAB1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Tryptases are serine proteases with trypsin-like specificity. Together with chymases and Cathepsin G, tryptases are important players in mast cell mediation of inflammatory and allergic responses. Tryptase alpha/beta-1(T...
TMPJ-00071	EPO/Erythropoietin Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Erythropoietin (EPO) is a glycoprotein hormone that is principally known for its role in erythropoiesis, where it is responsible for stimulating proliferation and differentiation of erythroid progenitor cells. Erythropoi...
TMPY-04826	LILRB5/CD85c Protein, Human, Recombinant (His)	Human	HEK293 Cells
	A genetic variant in LILRB5 (leukocyte immunoglobulin-like receptor subfamily-B) (rs12975366: T > C: Asp247Gly) has been reported to be associated with lower creatine phosphokinase (CK) and lactate dehydrogenase (LDH) le...
TMPY-04483	IRAK4 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Interleukin-1 receptor-associated kinase 4, also known as Renal carcinoma antigen NY-REN-64, IRAK-4, and IRAK4, is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, and Pelle subfamily. IRAK4...
TMPY-03425	Tau Protein, Human, Recombinant (His)	Human	E. coli
	MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are...
TMPY-00539	GSTA1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	GSTA1 (Glutathione S-Transferase Alpha 1) is a Protein Coding gene. This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds. Glutathione S-transferases (GSTs) ...
TMPJ-01466	Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His)	Human	HEK293 Cells
	TNFRSF11B is a secreted protein, containing 2 death domains and 4 TNFR-Cys repeats. TNFRSF11B is a decoy receptor for the receptor activator of nuclear factor kappa B ligand (RANKL). By binding RANKL, TNFRSF11B inhibits ...
TMPY-01964	CD16a Protein, Human, Recombinant (F176V, His)	Human	HEK293 Cells
	The Fc receptor with low affinity for IgG (FCGR3, or CD16) is encoded by 2 nearly identical genes, FCGR3A and FCGR3B, resulting in tissue-specific expression of alternative membrane-anchored isoforms. FCGR3A, it is also ...
TMPJ-00137	APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His)	Human	HEK293 Cells
	APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to relea...
TMPY-00566	CCL18 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	CCL18 is a chemotactic cytokine involved in the pathogenesis and progression of various disorders, including cancer. Proof showed high levels of CCL18 in the serum of epithelial ovarian carcinoma patients suggesting its...
TMPY-00021	PADI4 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Protein-arginine deiminase type-4, also known as HL-6 PAD, Peptidylarginine deiminase IV, Protein-arginine deiminase type I V and PADI4, is a cytoplasm and nucleus protein that belongs to the protein arginine deiminase f...
TMPY-01101	Coagulation factor X/F10 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Coagulation factor X, also known as FX, F10, Eponym Stuart-Prower factor, and thrombokinase, is an enzyme of the coagulation cascade. It is one of the vitamin K-dependent serine proteases, and plays a crucial role in the...
TMPK-01202	CD93/C1qR1 Protein, Human, Recombinant (His&Avi), Biotinylated	Human	HEK293 Cells
	CD93 has been shown critical roles in inflammatory and immune diseases. CD93 silencing increased IL-6 and TSLP, but not IL-33 levels in culture supernatants. HDM-induced asthma mice showed significant airway hyperrespons...
TMPH-02371	SHV-5 Protein, Klebsiella pneumoniae, Recombinant (His & Myc)	Klebsiella pneumoniae	E. coli
	SHV enzymes hydrolyze broad spectrum cephalosporins notably cefotaxime and ceftazidime. SHV-5 causes particularly high levels of resistance to aztreonam and ceftazidime.
TMPH-00635	Heat-stable enterotoxin ST-IA/ST-P Protein, E. coli, Recombinant (GST)	E. coli	E. coli
	Toxin which activates the particulate form of guanylate cyclase and increases cyclic GMP levels within the host intestinal epithelial cells.
TMPH-00633	Heat-stable enterotoxin A2 Protein, E. coli, Recombinant (His & Myc & SUMO)	E. coli	E. coli
	Toxin which activates the particulate form of guanylate cyclase and increases cyclic GMP levels within the host intestinal epithelial cells.
TMPK-01092	OSCAR Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Osteoclast-associated receptor (OSCAR) is a co-stimulatory receptor in osteoclastogenesis. Synovial tissues from active rheumatoid arthritis (RA) patients express higher levels of OSCAR compared with osteoarthritic and n...
TMPK-01117	OSCAR Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Osteoclast-associated receptor (OSCAR) is a co-stimulatory receptor in osteoclastogenesis. Synovial tissues from active rheumatoid arthritis (RA) patients express higher levels of OSCAR compared with osteoarthritic and n...
TMPK-00299	ANGPTL2 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Angiopoietin-like 2 (ANGPTL2) is a proinflammatory protein belonging to the angiopoietin-like family. ANGPTL2 is secreted and detected in the systemic circulation. Different observational clinical studies reported that c...
TMPK-01069	TMEM106B Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	TMEM106B is a well-recognised risk factor for FTD caused by GRN mutation. Elegant experiments have suggested that increased risk for FTD is due to elevated levels of TMEM106B (Nicholson et al, 2013; Gallagher et al, 2017...
TMPY-03491	Lysozyme 2 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	The lysozyme 2 gene is a member of a family of lysozyme-like genes. Lysozymes, especially C-type lysozymes, are well-recognized bacteriolytic factors widely distributed in the animal kingdom and play a mainly protective ...
TMPJ-00978	PIP4K2A Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (PIP4K2A) is a member of the phosphatidylinositol-4-phosphate 5-kinase family. It contains 1 PIPK domain and is expressed ubiquitously, with high levels in the brain...
TMPK-00298	ANGPTL2 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Angiopoietin-like 2 (ANGPTL2) is a proinflammatory protein belonging to the angiopoietin-like family. ANGPTL2 is secreted and detected in the systemic circulation. Different observational clinical studies reported that c...
TMPY-03461	GABARAPL2 Protein, Human, Recombinant (His)	Human	E. coli
	GATE-16, also known as ATG8, belongs to the MAP1 LC3 family. It is expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. GATE-16 is expressed at very low levels in lung, thymus and...
TMPH-03715	Y-STB Protein, Yersinia enterocolitica, Recombinant (His & SUMO)	Yersinia enterocolitica	E. coli
	Toxin which activates the particulate form of guanylate cyclase and increases cyclic GMP levels within the host intestinal epithelial cells. Could play an important role in pathogenesis.
TMPH-01549	Interferon epsilon/IFNE Protein, Human, Recombinant (His)	Human	E. coli
	Type I interferon required for maintaining basal levels of IFN-regulated genes, including 2'-5'-oligoadenylate synthetase, IRF7 and ISG15, in the female reproductive tract. Directly mediates protection against viral and ...
TMPK-00149	Fc epsilon RI alpha/FCER1a Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Known susceptibility genes to atopy and asthma have been identified by linkage or associations with clinical phenotypes, including total serum IgE levels. IgE-mediated sensitivity reactions require a high-affinity IgE re...
TMPH-02331	GLRA1 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine. Channel opening is also triggered by taurine and beta-alanine. Channel characteristics depend on the subunit co...
TMPJ-00902	Kell Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Kell blood group glycoprotein (KEL) is a single-pass type II membrane protein which belongs to the peptidase M13 family. It is expressed in Expressed at high levels in erythrocytes and testis, and, at lower levels, in sk...
TMPJ-01258	RNASE6 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Ribonuclease K6 (RNASE6) is a secreted protein that belongs to the pancreatic ribonuclease family. Human RNASE6 is synthesized as a 150 amino acid precursor that contains a 23 amino acid signal sequence, and a 127 amino ...
TMPH-02851	PDIA2 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded protei...
TMPH-02198	TXNRD2 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Involved in the control of reactive oxygen species levels and the regulation of mitochondrial redox homeostasis. Maintains thioredoxin in a reduced state. May play a role in redox-regulated cell signaling.
TMPH-00574	Adenylate cyclase Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Catalyzes the formation of the second messenger cAMP from ATP. Its transcript is probably degraded by endoribonuclease LS (rnlA), decreasing cAMP levels and the negative regulator Crp-cAMP, which then induces its own tra...
TMPH-00844	HSD11B2 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids. HS...
TMPJ-01390	MINPP1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Multiple Inositol Polyphosphate Phosphatase 1/MINPP1 is an enzyme that removes 3-phosphate from inositol phosphate substrates. MINPP1 also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate. MINPP1 is synth...
TMPH-00634	Heat-stable enterotoxin ST-2 Protein, E. coli, Recombinant	E. coli	E. coli
	Toxin which activates the particulate form of guanylate cyclase and increases cyclic GMP levels within the host intestinal epithelial cells. Heat-stable enterotoxin ST-2 Protein, E. coli, Recombinant is expressed in E. c...
TMPJ-01044	NCALD Protein, Human, Recombinant (His)	Human	E. coli
	Neurocalcin-delta (NCALD) is a neuronal calcium-binding protein that belongs to the neuronal calcium sensor (NCS) family. It expressed in mammalian brains. NCALD contains an N-terminal myristoylation signal and four EF-h...
TMPJ-01142	CDO1 Protein, Human, Recombinant (His)	Human	E. coli
	Cysteine Dioxygenase Type 1 (CDO1) is a mammalian non-heme iron enzyme that belongs to the cysteine dioxygenase family. CDO1 is highly expressed in the liver and placenta, and has a low expression in heart, brain and pan...
TMPJ-01185	SULT1C4 Protein, Human, Recombinant (His)	Human	E. coli
	Human Sulfotransferase (SULT1C4) is an enzyme that in humans is encoded by the SULT1C4 gene, belongs to the sulfotransferase 1 family. SULT1C4 is expressed at high levels in fetal lung and kidney and at low levels in fet...
TMPH-03293	FGF-23 Protein, Rat, Recombinant (E. coli, His)	Rat	E. coli
	Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Regulator of vitamin-D metabolism. Negatively regulates osteoblasts differentiation and matrix mineralization. Ac...
TMPJ-01007	HRSP12 Protein, Human, Recombinant (His)	Human	E. coli
	Heat-Responsive Protein 12 (HRSP12) is an endoribonuclease that belongs to the Rut family. HRSP12 is found mainly in the human adult kidney and liver and is responsible for inhibiting protein translation by cleaving mRNA...
TMPY-01771	Latexin Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Latexin, also known as endogenous carboxypeptidase inhibitor, tissue carboxypeptidase inhibitor, TCI, ECI, and LXN, is a cytoplasm protein that belongs to the protease inhibitor I47 (latexin) family. It is highly express...
TMPY-02757	TWEAKR/TNFRSF12A Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Fn14 (tumor necrosis factor receptor superfamily, member 12A), also known as TNFRSF12A, is the receptor for TNFSF12/TWEAK. Fn14 shares 82% amino acid identity with the mouse sequence. It contains a signal peptide, an ext...
TMPH-00648	LapB Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of prote...
TMPK-00050	Leptin Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Leptin has key roles in the regulation of energy balance, body weight, metabolism, and endocrine function. Leptin levels are undetectable or very low in patients with lipodystrophy, hypothalamic amenorrhea, and congenita...
TMPK-01028	BSPII Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Osteopontin (OPN), bone sialoprotein (BSPII), and osteonectin (ON) belong to a family of glycoproteins, which have been linked to cancer metastasis and progression. Here, we report on the selection of antisense oligonucl...
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Apolipoprotein A-IV/APOA4 Protein, Human, Recombinant (His)

TMPY-04310

Species: Human

Expression System: HEK293 Cells

HGF Protein, Human, Recombinant (hFc)

TMPK-00369

Species: Human

Expression System: HEK293 Cells

CXCL11 Protein, Human, Recombinant

TMPY-03274

Species: Human

Expression System: E. coli

TSHR Protein, Human, Recombinant (His)

TMPY-04853

Species: Human

Expression System: Baculovirus Insect Cells

TPSAB1 Protein, Human, Recombinant (His)

TMPJ-01204

Species: Human

Expression System: HEK293 Cells

EPO/Erythropoietin Protein, Human, Recombinant (His)

TMPJ-00071

Species: Human

Expression System: HEK293 Cells

LILRB5/CD85c Protein, Human, Recombinant (His)

TMPY-04826

Species: Human

Expression System: HEK293 Cells

IRAK4 Protein, Human, Recombinant (His)

TMPY-04483

Species: Human

Expression System: Baculovirus Insect Cells

Tau Protein, Human, Recombinant (His)

TMPY-03425

Species: Human

Expression System: E. coli

GSTA1 Protein, Human, Recombinant (His)

TMPY-00539

Species: Human

Expression System: HEK293 Cells

Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His)

TMPJ-01466

Species: Human

Expression System: HEK293 Cells

CD16a Protein, Human, Recombinant (F176V, His)

TMPY-01964

Species: Human

Expression System: HEK293 Cells

APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His)

TMPJ-00137

Species: Human

Expression System: HEK293 Cells

CCL18 Protein, Human, Recombinant (His)

TMPY-00566

Species: Human

Expression System: P. pastoris (Yeast)

PADI4 Protein, Human, Recombinant (His)

TMPY-00021

Species: Human

Expression System: Baculovirus Insect Cells

Coagulation factor X/F10 Protein, Human, Recombinant (His)

TMPY-01101

Species: Human

Expression System: Baculovirus Insect Cells

CD93/C1qR1 Protein, Human, Recombinant (His&Avi), Biotinylated

TMPK-01202

Species: Human

Expression System: HEK293 Cells

SHV-5 Protein, Klebsiella pneumoniae, Recombinant (His & Myc)

TMPH-02371

Species: Klebsiella pneumoniae

Expression System: E. coli

Heat-stable enterotoxin ST-IA/ST-P Protein, E. coli, Recombinant (GST)

TMPH-00635

Species: E. coli

Expression System: E. coli

Heat-stable enterotoxin A2 Protein, E. coli, Recombinant (His & Myc & SUMO)

TMPH-00633

Species: E. coli

Expression System: E. coli

OSCAR Protein, Human, Recombinant (hFc)

TMPK-01092

Species: Human

Expression System: HEK293 Cells

OSCAR Protein, Mouse, Recombinant (hFc)

TMPK-01117

Species: Mouse

Expression System: HEK293 Cells

ANGPTL2 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00299

Species: Human

Expression System: HEK293 Cells

TMEM106B Protein, Mouse, Recombinant (hFc)

TMPK-01069

Species: Mouse

Expression System: HEK293 Cells

Lysozyme 2 Protein, Human, Recombinant (His)

TMPY-03491

Species: Human

Expression System: Baculovirus Insect Cells

PIP4K2A Protein, Human, Recombinant (His)

TMPJ-00978

Species: Human

Expression System: HEK293 Cells

ANGPTL2 Protein, Human, Recombinant (His & Avi)

TMPK-00298

Species: Human

Expression System: HEK293 Cells

GABARAPL2 Protein, Human, Recombinant (His)

TMPY-03461

Species: Human

Expression System: E. coli

Y-STB Protein, Yersinia enterocolitica, Recombinant (His & SUMO)

TMPH-03715

Species: Yersinia enterocolitica

Expression System: E. coli

Interferon epsilon/IFNE Protein, Human, Recombinant (His)

TMPH-01549

Species: Human

Expression System: E. coli

Fc epsilon RI alpha/FCER1a Protein, Human, Recombinant (His)

TMPK-00149

Species: Human

Expression System: HEK293 Cells

GLRA1 Protein, Human, Recombinant (His & Myc)

TMPH-02331

Species: Human

Expression System: E. coli

Kell Protein, Human, Recombinant (His)

TMPJ-00902

Species: Human

Expression System: HEK293 Cells

RNASE6 Protein, Human, Recombinant (His)

TMPJ-01258

Species: Human

Expression System: HEK293 Cells

PDIA2 Protein, Mouse, Recombinant (His & SUMO)

TMPH-02851

Species: Mouse

Expression System: E. coli

TXNRD2 Protein, Human, Recombinant (His & SUMO)

TMPH-02198

Species: Human

Expression System: E. coli

Adenylate cyclase Protein, E. coli, Recombinant (His)

TMPH-00574

Species: E. coli

Expression System: E. coli

HSD11B2 Protein, Human, Recombinant (His)

TMPH-00844

Species: Human

Expression System: P. pastoris (Yeast)

MINPP1 Protein, Human, Recombinant (His)

TMPJ-01390

Species: Human

Expression System: HEK293 Cells

Heat-stable enterotoxin ST-2 Protein, E. coli, Recombinant

TMPH-00634

Species: E. coli

Expression System: E. coli

NCALD Protein, Human, Recombinant (His)

TMPJ-01044

Species: Human

Expression System: E. coli

CDO1 Protein, Human, Recombinant (His)

TMPJ-01142

Species: Human

Expression System: E. coli

SULT1C4 Protein, Human, Recombinant (His)

TMPJ-01185

Species: Human

Expression System: E. coli

FGF-23 Protein, Rat, Recombinant (E. coli, His)

TMPH-03293

Species: Rat

Expression System: E. coli

HRSP12 Protein, Human, Recombinant (His)

TMPJ-01007

Species: Human

Expression System: E. coli

Latexin Protein, Mouse, Recombinant (His)

TMPY-01771

Species: Mouse

Expression System: E. coli

TWEAKR/TNFRSF12A Protein, Human, Recombinant (hFc)

TMPY-02757

Species: Human

Expression System: HEK293 Cells

LapB Protein, E. coli, Recombinant (His)

TMPH-00648

Species: E. coli

Expression System: E. coli

Leptin Protein, Mouse, Recombinant (hFc)

TMPK-00050

Species: Mouse

Expression System: HEK293 Cells

BSPII Protein, Mouse, Recombinant (His)

TMPK-01028

Species: Mouse

Expression System: HEK293 Cells

--------- More ---------

カタログ番号	製品名
L1900	Anti-Diabetic Compound Library	683 compounds
	A unique collection of 683 diabetes related compounds;
L8500	HIF-1 Signaling Pathway Compound Library	1336 compounds
	A unique collection of 1336 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies；
L1300	PI3K-AKT-mTOR Compound Library	420 compounds
	A unique collection of 420 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with PI3K/Akt/mTOR signaling;
L9840	Anti-Alzheimer's Disease Compound Library	986 compounds
	A unique collection of 986 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS.

ライブラリー

Anti-Diabetic Compound Library

L1900

Compounds: 683

HIF-1 Signaling Pathway Compound Library

L8500

Compounds: 1336

PI3K-AKT-mTOR Compound Library

L1300

Compounds: 420

Anti-Alzheimer's Disease Compound Library

L9840

Compounds: 986