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カタログ番号	製品名	別名	ターゲット
T7677	JNK Inhibitor VIII	TCS JNK 6o	JNK
	JNK Inhibitor VIII (TCS JNK 6o) is an ATP-competitive selective inhibitor of c-Jun N-terminal kinase (JNK)(IC50 values of 45 nM and 160 nM for JNK-1 and -2, respectively).		JNK
T3598	JNK-IN-7	JNK inhibitor	JNK
	JNK-IN-7 (JNK inhibitor) is a selective JNK1/2/3 inhibitor (IC50: 1.54/1.99/0.75 nM). It can also inhibit phosphorylation of c-Jun, which is a substrate of JNK kinase.		JNK
T2668	JNK-IN-8	JNK Inhibitor XVI	JNK , c-Kit
	JNK-IN-8 (JNK Inhibitor XVI) is an irreversible JNK1/2/4 inhibitor (IC50: 4.7/18.7/1 nM). The selectivity is higher 10-fold than MNK2, Fms and no inhibition of Met, c-Kit, PDGFRβ in A375 cell line.		JNK , c-Kit
T38260	SP 600125, negative control	JNK Inhibitor II, negative control
	SP 600125, negative control is a methylated analog of SP 600125 and can be used as a negative control for SP 600125. SP 600125, negative control inhibits DTP3 and GADD45β/MKK7 (growth arrest and DNA damage-inducible β/me...
T3109	SP600125	1PMV,JNK Inhibitor II,Nsc75890,Pyrazolanthrone	Apoptosis , Ferroptosis , Trk receptor , JNK , Aurora Kinase , Autophagy
	SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitive properties. SP600125 inhibits autophagy and induces apoptosis.
T2234	TCS JNK 5a	SC202671,SC 202671,N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide,JNK Inhibitor IX,SC-202671	Apoptosis , JNK
	TCS JNK 5a (SC202671) is an effective, specific inhibitor of JNK3(pIC50= 6.7), JNK2(pIC50=6.5).		Apoptosis , JNK
T6784	BI-78D3		JNK
	BI-78D3, a competitive JNK inhibitor. IC50 of BI-78D3 is 280 nM that displays > 100 fold selectivity over p38α, and have no activity at mTOR and PI-3K.		JNK
T3200	DB07268		JNK
	DB07268 is a potent and selective JNK1 inhibitor.		JNK
T16927	SR-3306		JNK
	SR-3306 is a potent and highly inhibitor of brain penetrant JNK.		JNK
T2675	Bentamapimod	AS 602801	JNK
	Bentamapimod (AS 602801) is a novel, orally active inhibitor of JNK.		JNK
T14895	Tanzisertib	CC-930	JNK
	Tanzisertib (CC-930) (CC-930) is a potent inhibitor of JNK1/2/3 with IC50s of 61/7/6 nM, respectively, with potential antifibrotic activity.		JNK
T12189	NBDHEX		Apoptosis , Glutathione Peroxidase , Autophagy
	NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1) .		Apoptosis , Glutathione Peroxidase , Autophagy
T2035	WHI-P258		EGFR , JAK , JNK
	WHI-P258 is a dimethoxyquinazoline inhibitor of JAK3. This compound binds JAK3 weakly and may be used as a JAK-binding negative control in the development of new therapeutics.		EGFR , JAK , JNK
T8477	IQ-3		JNK
	IQ3 is a selective inhibitor of JNK3(JNK3, JNK1 and JNK2 with Kd of 66 nM, 240 nM and 290 nM, respectively). IQ 3 inhibits NF-κB/AP1 transcriptional activity in THP1-Blue cells with IC50 of 1.4 μM, also inhibits TNF-α an...		JNK
T2343	AS601245		JNK
	AS601245 is an inhibitor of the c-Jun NH2-terminal kinase (JNK), with neuroprotective properties.		JNK
T9688	CC-90001		JNK
	CC-90001 is an orally administered c-Jun N-terminal kinase (JNK) inhibitor with bias for JNK1 over JNK2.		JNK
T5833	CC-401 Hydrochloride	CC401 HCl	JNK
	CC-401 Hydrochloride (CC401 HCl) is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor (Ki of 25 to 50 nM.)with potential antineoplastic activity.		JNK
T13018	SU3327	halicin	JNK
	SU3327 (halicin) is a potent, selective and substrate-competitive inhibitor of JNK(IC50 of 0.7 μM).		JNK
T13099	TC ASK 10		ASK , MAPK
			ASK , MAPK
T9010	IMM-H007		Others , AMPK
	IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expression		Others , AMPK
T3627	IQ-1S free acid	IQ-1,IQ-1S,IQ-1S (free acid)	NF-κB , JNK
	IQ-1S free acid (IQ-1S) is an effective and specific c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity. IQ-1S can reduce inflammation and cartilage loss associated with CIA and can se...		NF-κB , JNK
T6927	Pamapimod	R1503,Ro4402257	p38 MAPK , Autophagy
	Pamapimod (R1503) (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase. It inhibits p38α and p38β enzymatic activity with IC50 values of 0.014±0.002 and 0.48± 0.04 microM, respectiv...		p38 MAPK , Autophagy
T5097	Ezatiostat	TER199(free base),TLK199	Apoptosis , Glutathione Peroxidase , GST
	Ezatiostat (TER199(free base)) is a tripeptide analog of glutathione that can selectively inhibit GSTP1-1 catalytic activity.		Apoptosis , Glutathione Peroxidase , GST
T0860	Mefloquine hydrochloride	Mefloquin hydrochloride,Mefloquine HCl	Potassium Channel , SARS-CoV , Reactive Oxygen Species , Parasite , Autophagy
	Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.
T9138	Indirubin-3′-oxime	Indirubin-3'-monoxime	GSK-3 , CDK , JNK
	Indirubin-3′-oxime is an effective inhibitor of cyclin-dependent protein kinases, and may play an obligate role in neuronal apoptosis in Alzheimer's disease.		GSK-3 , CDK , JNK
T40248	JNK3 inhibitor-1	JNK3 inhibitor-1
	JNK3 inhibitor-1 is a highly potent and selective compound that specifically inhibits JNK3 with an impressive IC50 value of 0.005 μM. In addition to its remarkable inhibitory effects, JNK3 inhibitor-1 possesses excellent...
T0860L	Mefloquine	Ro215998,WR 142490,Ro-215998,Lariam,Ro 215998	Others
	Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor. Mefloquine is also a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. Mefloquine can be used for malaria, systemic l...		Others
T1606	Fasudil	HA-1077,AT877	ROCK , Serine/threonin kinase , Calcium Channel , PKA , PKC , Autophagy
	Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.
T38665	OVA-E1 peptide TFA	OVA-E1 peptide TFA	p38 MAPK , JNK
	OVA-E1 peptide TFA activates the p38 and JNK cascades similarly in mutant and wild-type thymocytes.		p38 MAPK , JNK
T22776	Ezatiostat hydrochloride	TLK199 HCl,TER199	Glutathione Peroxidase
	Ezatiostat hydrochloride (TLK199 HCl) is an effective inhibitor of glutathione S-transferase. Ezatiostat hydrochloride is a novel glutathione analog and the potential treatment of cytopenias. In addition, Ezatiostat hydr...		Glutathione Peroxidase
T3060	Fasudil hydrochloride	Fasudil (HA-1077) HCl,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877	ROCK , Serine/threonin kinase , Calcium Channel , HIV Protease , PKA , PKC , Autophagy
	Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.
T5094	IRAK inhibitor 1		IRAK , JNK
	IRAK inhibitor 1 is an effective IRAK-4 inhibitor (IC50: 216 nM), is poorly active against JNK-1 (IC50: 3.801 μM) and JNK-2 (IC50>10 μM).		IRAK , JNK
T24784	SF5	SF-5,SF 5	Apoptosis
	SF5 is an inhibitor of the apoptosis pathway. Which is through the JNK-p53-caspase apoptotic cascade.		Apoptosis
T10937L	D-JNKI-1 acetate	D-JNKI-1 acetate(1445179-97-4 Free base),AM-111 acetate	JNK
	D-JNKI-1 acetate (AM-111 acetate) is a highly potent and cell-permeable peptide inhibitor of JNK.		JNK
T60534	JNK-IN-11		JNK
	JNK-IN-11 is a potent JNK inhibitor that inhibits JNK1, JNK2, and JNK3 with IC50 values of 1.8, 21.4, and 2.2 µM, respectively.JNK-IN-11 can be used to study abnormalities in immune function.		JNK
TP1897L1	JIP-1 (153-163) acetate(438567-88-5 free base)		JNK
	JIP-1 (153-163) acetate(438567-88-5 free base) is a peptide inhibitor of c-Jun N-terminal kinase (JNK), based on residues 153-163 of JNK-interacting protein-1 (JIP-1). JIP-1 (153-163) acetate(438567-88-5 free base) binds...		JNK
T8661	AS601245.2TFA (345987-15-7 free base)	AS601245.2TFA	JNK
	AS601245.2TFA (345987-15-7 free base) (AS601245.2TFA) is a cell-permeable Inhibitor of JNK (IC50s of 150, 220, and 70 nM for hJNK1, hJNK2, and hJNK3, respectively).		JNK
T7280	CAY10594		Phospholipase
	CAY10594 is a potent phospholipase D2(PLD2) inhibitor. CAY10594 ameliorates acetaminophen-induced acute liver injury by regulating the phosphorylated-GSK-3β/JNK axis.		Phospholipase
T19814	CP-380736	PF 00520893,CP380736,PF00520893,CP 380736,PF-00520893	EGFR
	CP-380736 (PF-00520893) is an epidermal growth factor receptor (EGFR) inhibitor. EGFR is a tyrosine kinase that activates MAPK, JNK, and Akt pathways, and is an important mediator of several types of cancer.		EGFR
T24855	TASIN-1 Hydrochloride	TASIN-1 HCl,TASIN 1 HCl,TASIN1 HCl	APC
	TASIN-1 Hydrochloride (TASIN-1 HCl) is a selective inhibitor of truncated APC that acts by selectively killing colorectal cancer cells that express truncated APC by reducing cellular cholesterol levels and inducing apopt...		APC
T8233	BRD3308		Apoptosis , HIV Protease , HDAC
	BRD3308 is a highly selective inhibitor of HDAC3(IC50 of 54 nM), attenuating PE-mediated phosphorylation of ERK but not JNK.		Apoptosis , HIV Protease , HDAC
T22343	HKB99		Others
	HKB99 is a mutational inhibitor of phosphoglycerate mutase 1 (PGAM1).HKB99 increases oxidative stress, activates JNK/c-Jun, and inhibits AKT and ERK[1].HKB99 inhibits the formation of invasive pseudopods and raises the l...		Others
T6611	NSC697923	2-[(4-methylphenyl)sulfonyl]-5-nitrofuran	E1/E2/E3 Enzyme
	NSC-697923 (2-[(4-methylphenyl)sulfonyl]-5-nitrofuran), a potent inhibitor of UBE2N (ubiquitin-conjugating enzyme E2 N, Ubc13), exhibits its role in inducing cell death in neuroblastoma (NB) cells through two distinct me...		E1/E2/E3 Enzyme
T6144	KB-R7943 mesylate	KB-R7943	Na+/Ca2+ Exchanger , Autophagy
	KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with IC50 of 5.7±2.1 μM.		Na+/Ca2+ Exchanger , Autophagy
T22927	LL-Z 1640-4		Others
	A signal-specific JNK/p38 pathway and TAK 1 inhibitor		Others
T69468	NEPP-11
	NEPP-11 is a selective JNK signaling pathway inhibitor.
T73109	JNK-1-IN-1
	JNK-1-IN-1 is an inhibitor specifically targeting JNK-1, also exhibiting inhibition of MKK7 with an IC50 value of 7.8μM. It binds to MKK7cp, further reinforcing its role as a JNK-1 inhibitor.
T26349	ZG-10	ZG 10,ZG10
	ZG-10 is a JNK1 inhibitor targeting JNK and p38 signaling.
T22639	CC-401		Others
	CC-401 is a specific inhibitor of JNK (Ki: 25-50nM).		Others
T69527	Erioflorin
	Erioflorin is an ATP-competitive selective c-Jun N-terminal kinase (JNK) inhibitor.

Compounds

JNK Inhibitor VIII

T7677

Synonym: TCS JNK 6o

Target: JNK

JNK-IN-7

T3598

Synonym: JNK inhibitor

Target: JNK

JNK-IN-8

T2668

Synonym: JNK Inhibitor XVI

Target: JNK, c-Kit

SP 600125, negative control

T38260

Synonym: JNK Inhibitor II, negative control

Target:

SP600125

T3109

Synonym: 1PMV,JNK Inhibitor II,Nsc75890,Pyrazolanthrone

Target: Apoptosis, Ferroptosis, Trk receptor, JNK, Aurora Kinase, Autophagy

TCS JNK 5a

T2234

Synonym: SC202671,SC 202671,N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide,JNK Inhibitor IX,SC-202671

Target: Apoptosis, JNK

Target: Apoptosis, Glutathione Peroxidase, Autophagy

WHI-P258

T2035

Synonym:

Target: EGFR, JAK, JNK

Synonym: IQ-1,IQ-1S,IQ-1S (free acid)

Target: NF-κB, JNK

Pamapimod

T6927

Synonym: R1503,Ro4402257

Target: p38 MAPK, Autophagy

Ezatiostat

T5097

Synonym: TER199(free base),TLK199

Target: Apoptosis, Glutathione Peroxidase, GST

Mefloquine hydrochloride

T0860

Synonym: Mefloquin hydrochloride,Mefloquine HCl

Target: Potassium Channel, SARS-CoV, Reactive Oxygen Species, Parasite, Autophagy

Indirubin-3′-oxime

T9138

Synonym: Indirubin-3'-monoxime

Target: GSK-3, CDK, JNK

JNK3 inhibitor-1

T40248

Synonym: JNK3 inhibitor-1

Target:

Mefloquine

T0860L

Synonym: Ro215998,WR 142490,Ro-215998,Lariam,Ro 215998

Target: Others

Fasudil

T1606

Synonym: HA-1077,AT877

Target: ROCK, Serine/threonin kinase, Calcium Channel, PKA, PKC, Autophagy

OVA-E1 peptide TFA

T38665

Synonym: OVA-E1 peptide TFA

Target: p38 MAPK, JNK

Ezatiostat hydrochloride

T22776

Synonym: TLK199 HCl,TER199

Target: Glutathione Peroxidase

Fasudil hydrochloride

T3060

Synonym: Fasudil (HA-1077) HCl,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877

Target: ROCK, Serine/threonin kinase, Calcium Channel, HIV Protease, PKA, PKC, Autophagy

Synonym: D-JNKI-1 acetate(1445179-97-4 Free base),AM-111 acetate

JIP-1 (153-163) acetate(438567-88-5 free base)

TP1897L1

Synonym:

Target: JNK

AS601245.2TFA (345987-15-7 free base)

T8661

Synonym: AS601245.2TFA

Target: Phospholipase

CP-380736

T19814

Synonym: PF 00520893,CP380736,PF00520893,CP 380736,PF-00520893

Target: EGFR

TASIN-1 Hydrochloride

T24855

Synonym: TASIN-1 HCl,TASIN 1 HCl,TASIN1 HCl

Target: Apoptosis, HIV Protease, HDAC

Synonym: 2-[(4-methylphenyl)sulfonyl]-5-nitrofuran

Target: E1/E2/E3 Enzyme

KB-R7943 mesylate

T6144

Synonym: KB-R7943

Target: Na+/Ca2+ Exchanger, Autophagy

カタログ番号	製品名	別名	ターゲット
TQ0089	Juglanin		Apoptosis , JNK , Autophagy
	Juglanin is a JNK activator. Juglanin with inflammation and anti-tumor activities. It can induce apoptosis and autophagy on human breast cancer cells.		Apoptosis , JNK , Autophagy
T5S2283	Sesamolin		p38 MAPK , Caspase , JNK
	1. Sesamolin and Sesamin has neuroprotective effect. 2. Sesamolin protects microglia against H2O2-induced cell injury, by inhibiting of p38 MAPK and caspase-3 activation and ROS production. 3. Sesamolin and Sesamin can s...		p38 MAPK , Caspase , JNK
T7190	Actein		Apoptosis , Akt , JNK , Autophagy
	Actein has a stimulatory effect on osteoblastic bone formation or has potential activity against osteoporosis, it also can prevent oxidative damage to osteoblasts in osteoporotic patients. Actein's ability to pathways in...		Apoptosis , Akt , JNK , Autophagy
T3S1641	Esculentoside H		TNF , NF-κB , JNK
	Phytolaccaceae has anti-tumor activity, the mechanism may be related to the capacity of Esculentoside H for TNF release.		TNF , NF-κB , JNK
TMA0507	Tomatidine		NF-κB , JNK , Autophagy
	Tomatidine serves as an anti-inflammatory agent by inhibiting NF-κB and JNK signaling pathways. Additionally, it induces autophagy in both mammalian cells and C. elegans.		NF-κB , JNK , Autophagy
TN3967	Epieriocalyxin A		ERK , BCL , ROS , Caspase , DNA/RNA Synthesis , JNK
	Epieriocalyxin A can suppress Caco-2 colon cancer cell growth. It could be a potential drug for colon cancer therapy in the future.		ERK , BCL , ROS , Caspase , DNA/RNA Synthesis , JNK
T3876	Loureirin B		PAI-1 , ERK , Potassium Channel , JNK
	Loureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress TGF-β1-induced fibrosis, during which TGF-β1/Smad2/3 pathw...		PAI-1 , ERK , Potassium Channel , JNK
T3895	Polyphyllin I		Apoptosis , Akt , JNK , PDK , mTOR , Autophagy
	Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C, and cleaved-caspase-3 levels. Polyphyllin D ha...		Apoptosis , Akt , JNK , PDK , mTOR , Autophagy
T5574	Guggulsterone	Guggulsterone E&Z	Apoptosis , FXR , Akt , Caspase , JNK , Autophagy
	Guggulsterone (Guggulsterone E&Z) E&Z is a 3-hydroxy steroid. It has a role as an androgen.		Apoptosis , FXR , Akt , Caspase , JNK , Autophagy
T6758	Anisomycin	Flagecidin,NSC 76712,Wuningmeisu C	Apoptosis , DNA/RNA Synthesis , Antibacterial , Antibiotic , JNK
	Anisomycin (NSC-76712) is an antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system.
T6S1371	Isovitexin	Homovitexin,Saponaretin,Apigenin-6-C-Glucoside	NF-κB , JNK , Glucosidase
	1. Isovitexin (Apigenin-6-C-Glucoside) exhibits a potential antioxidant activity. 2. Isovitexin shows a strong antihyperglycemic action, inhibits α-glucosidase in vivo.		NF-κB , JNK , Glucosidase
T2973	Astragaloside IV	AST-IV,AS-IV	MMP , ERK , Estrogen/progestogen Receptor , JNK
	Astragaloside IV (AS-IV), an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cel...		MMP , ERK , Estrogen/progestogen Receptor , JNK
T4592	TOMATIDINE HYDROCHLORIDE	Tomatidine,Tomatidine HCl	Others , NF-κB , JNK , Autophagy
	Tomatidine hydrochloride (Tomatidine HCl) is a steriodal alkaloid structurally similar to Cyclopamine but does not inhibit hedgehog pathway. May be used as a negative control for Cyclopamine and KAAD-Cyclopamine. Tomatid...		Others , NF-κB , JNK , Autophagy
T13265	Urolithin B		ERK , NF-κB , Akt , Endogenous Metabolite , JNK , AMPK
	Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropical fruits, and medicinal herbs. Urolithin B inhibits NF-κB activit...		ERK , NF-κB , Akt , Endogenous Metabolite , JNK , AMPK
T2A2481	Taurochenodeoxycholic Acid	Chenodeoxycholyltaurine,TCDCA,Chenyltaurine,Taurochenodeoxycholate,12-Deoxycholyltaurine	Apoptosis , TNF , Caspase , Endogenous Metabolite
	Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.		Apoptosis , TNF , Caspase , Endogenous Metabolite
T1205	Chloramphenicol	Chlornitromycin,Levomycetin,Chloromycetin	ribosome , HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic
	Chloramphenicol (Chloromycetin), a broad-spectrum antibiotic, blocks bacterial protein synthesis.
TN2215	Taurochenodeoxycholic acid sodium	Sodium taurochenodeoxycholate	Apoptosis , Endogenous Metabolite
	Taurochenodeoxycholic acid sodium (Sodium taurochenodeoxycholate) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid sodium induces apoptosis and shows obvious anti-inflammatory and...		Apoptosis , Endogenous Metabolite
T2872	Ginsenoside Re	Ginsenoside B2,Panaxoside Re,Chikusetsusaponin Ivc,Sanchinoside Re	Beta Amyloid , NF-κB , Endogenous Metabolite , JNK
	Ginsenoside Re (Ginsenoside B2) may have properties that inhibit or prevent the growth of tumors.		Beta Amyloid , NF-κB , Endogenous Metabolite , JNK
T3816	Velutin		NF-κB , HIF/HIF Prolyl-Hydroxylase
	Velutin shows the strongest inhibitory effect in NF-κB activation and exhibits the greatest effects in blocking the degradation of inhibitor of NF-κB as well as in inhibiting mitogen-activated protein kinase p38 and JNK ...		NF-κB , HIF/HIF Prolyl-Hydroxylase
TCS2170	2,5-Dihydroxyacetophenone	Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP	ERK , NF-κB , Tyrosinase
	1. 2,5-Dihydroxyacetophenone (Quinacetophenone) possess anti-anxiety, and neuroprotective qualities. 2. 2,5-Dihydroxyacetophenone (Quinacetophenone) reatment can induce a sustained activation of JNK, ERK1/2, and p38 MAPK...		ERK , NF-κB , Tyrosinase
TN5387	Grasshopper ketone		ERK , p38 MAPK , NO Synthase , JNK
	Grasshopper ketone, isolated from the brown alga Sargassum, is a potent inhibitor of LPS-induced NO production in RAW 264.7 cells and induces anti-inflammatory effects by inhibiting MAPK (ERK, JNK and p38) and NF-κB p65 ...		ERK , p38 MAPK , NO Synthase , JNK

天然物製品

Juglanin

TQ0089

Synonym:

Target: Apoptosis, JNK, Autophagy

Sesamolin

T5S2283

Synonym:

Target: p38 MAPK, Caspase, JNK

Actein

T7190

Synonym:

Target: Apoptosis, Akt, JNK, Autophagy

Esculentoside H

T3S1641

Synonym:

Target: TNF, NF-κB, JNK

Tomatidine

TMA0507

Synonym:

Target: NF-κB, JNK, Autophagy

Epieriocalyxin A

TN3967

Synonym:

Target: ERK, BCL, ROS, Caspase, DNA/RNA Synthesis, JNK

Loureirin B

T3876

Synonym:

Target: PAI-1, ERK, Potassium Channel, JNK

Polyphyllin I

T3895

Synonym:

Target: Apoptosis, Akt, JNK, PDK, mTOR, Autophagy

Guggulsterone

T5574

Synonym: Guggulsterone E&Z

Target: Apoptosis, FXR, Akt, Caspase, JNK, Autophagy

Anisomycin

T6758

Synonym: Flagecidin,NSC 76712,Wuningmeisu C

Target: Apoptosis, DNA/RNA Synthesis, Antibacterial, Antibiotic, JNK

Isovitexin

T6S1371

Synonym: Homovitexin,Saponaretin,Apigenin-6-C-Glucoside

Target: NF-κB, JNK, Glucosidase

Astragaloside IV

T2973

Synonym: AST-IV,AS-IV

Target: MMP, ERK, Estrogen/progestogen Receptor, JNK

TOMATIDINE HYDROCHLORIDE

T4592

Synonym: Tomatidine,Tomatidine HCl

Target: Others, NF-κB, JNK, Autophagy

Urolithin B

T13265

Synonym:

Target: ERK, NF-κB, Akt, Endogenous Metabolite, JNK, AMPK

Taurochenodeoxycholic Acid

T2A2481

Synonym: Chenodeoxycholyltaurine,TCDCA,Chenyltaurine,Taurochenodeoxycholate,12-Deoxycholyltaurine

Target: Apoptosis, TNF, Caspase, Endogenous Metabolite

Chloramphenicol

T1205

Synonym: Chlornitromycin,Levomycetin,Chloromycetin

Target: ribosome, HIF/HIF Prolyl-Hydroxylase, Antibacterial, Antibiotic

Taurochenodeoxycholic acid sodium

TN2215

Synonym: Sodium taurochenodeoxycholate

Target: Apoptosis, Endogenous Metabolite

Ginsenoside Re

T2872

Synonym: Ginsenoside B2,Panaxoside Re,Chikusetsusaponin Ivc,Sanchinoside Re

Target: Beta Amyloid, NF-κB, Endogenous Metabolite, JNK

Velutin

T3816

Synonym:

Target: NF-κB, HIF/HIF Prolyl-Hydroxylase

2,5-Dihydroxyacetophenone

TCS2170

Synonym: Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP

Target: ERK, NF-κB, Tyrosinase

Grasshopper ketone

TN5387

Synonym:

Target: ERK, p38 MAPK, NO Synthase, JNK

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-00376	IL-17RD Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Interleukin-17 receptor D (IL-17 RD), also known as SEF (similar expression to FGFs), is a type I transmembrane protein that is found in both the cytoplasm and plasma membrane. IL-17RD functions as a feedback inhibitor o...
TMPY-02595	DUSP14 Protein, Human, Recombinant (His & MBP)	Human	E. coli
	Dual specific phosphatase 14 / MAP-kinase phophatase-6 (DUSP14 / MKP6) is a member of Dual-specificity phosphatases that is a subclass of protein tyrosine phosphatases (PTP) families that can dephosphorylate bothe phosph...
TMPH-02876	RIPK1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Serine-threonine kinase which is a key regulator of TNF-mediated apoptosis, necroptosis and inflammatory pathways. Exhibits kinase activity-dependent functions that regulate cell death and kinase-independent scaffold fun...

IL-17RD Protein, Human, Recombinant (hFc)

TMPJ-00376

Species: Human

Expression System: HEK293 Cells

DUSP14 Protein, Human, Recombinant (His & MBP)

TMPY-02595

Species: Human

Expression System: E. coli

RIPK1 Protein, Mouse, Recombinant (His)

TMPH-02876

Species: Mouse

Expression System: E. coli

カタログ番号	製品名
L1610	FDA-Approved Kinase Inhibitor Library	263 compounds
	A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.
L1600	Kinase Inhibitor Library	2720 compounds
	A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;

ライブラリー

FDA-Approved Kinase Inhibitor Library

L1610

Compounds: 263

Kinase Inhibitor Library

L1600

Compounds: 2720