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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T39516 | Bocidelpar | PPAR | |
Bocidelpar is a modulator of PPARδ with an EC50 of 7.80 nM and improves mitochondrial biogenesis and function in Duchenne Muscular Dystrophy muscle cells. | |||
T1264 | Ciprofibrate | Win35833 | PPAR |
Ciprofibrate (Win35833) is a fibrate derivative with antilipidemic activity. | |||
T10900 | CUDA | PPAR , Epoxide Hydrolase | |
CUDA is an effective soluble cyclohydrolase inhibitor with IC50 of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively. CUDA selectively increases the activity of peroxisome proliferator-activated receptor (PPAR... | |||
T14933 | Cetaben | Others | |
Cetaben is a PPARα-independent peroxisome proliferator and is a non-fibrate hypolipidemic drug. It potent reduces the concentration of cholesterol and triglycerides. | |||
T15945 | MA-0204 | PPAR | |
MA-0204 is a highly selective and orally available peroxisome proliferator-activated receptor δ (PPARδ) modulator (EC50s: 0.4 nM, 7.9 nM and 10 nM for human, mouse and rat PPARδ, respectively). It is a potential treatmen... | |||
T6689 | T0070907 | PPAR | |
T0070907(IC50=1 nM) , an effective and specific PPARγ inhibitor, with the >800-fold selectivity over PPARα and PPARδ. | |||
T1941 | GSK3787 | PPAR | |
GSK3787 is a specific and irreversible PPARδ inhibitor(pIC50= 6.6). | |||
T5532 | BMS-687453 | PPAR | |
BMS-687453 is a potent and selective PPAR alpha agonist, with an EC(50) of 10 nM for human PPARalpha and approximately 410-fold selectivity vs human PPARgamma in PPAR-GAL4 transactivation assays. | |||
TQ0156 | GW1929 | PPAR | |
GW1929 is a potent PPAR-γ agonist (pKi: 8.84 for human PPAR-γ; pEC50s of 8.56 and 8.27 for human and murine PPAR-γ). | |||
T8374 | LJ570 | PPAR | |
LJ570 is the first PPARα/γ dual agonist (PPARα,PPARγ with EC50s of 1.05 and 0.12 μM, respectively[) | |||
T4408 | Elafibranor | GFT505 | PPAR |
Elafibranor (GFT505) is an agonist of the peroxisome proliferator-activated receptor-α (PPAR-α) and peroxisome proliferator-activated receptor-δ (PPAR-δ) with EC50 values of 45 and 175 nM, respectively. | |||
T7159 | L-165041 | PPAR | |
L-165041 is a potent and selective agonist of the nuclear receptor PPARβ and PPARδ(Ki = 9 nM, EC50 = ~500 nM ,respectively) | |||
T2674 | GSK0660 | PPAR | |
GSK0660 is an antagonist and inverse agonist of PPARβ/δ. | |||
T7395 | Lanifibranor | IVA337 | PPAR |
Lanifibranor (IVA337) is an agonist of peroxisome proliferator-activated receptors (PPARs) with EC50 values of 1,537, 866, and 206 nM for human recombinant PPARα, PPARβ, and PPARγ, respectively, for transactivation activ... | |||
T24827 | SR 16832 | SR-16832,SR16832 | PPAR |
SR 16832 is a dual-site PPARγ inhibitor. It also inhibits the binding of endogenous ligands and transcriptional activity of PPARγ, more effectively than the orthosteric covalent antagonist GW 9662 and T 0070907. | |||
T9808 | Tetradecylthioacetic acid | PPAR | |
Tetradecylthioacetic acid is a synthetic fatty acid with a sulfur substitution in the β-position. This modification renders TTA unable to undergo complete β-oxidation and increases its biological activity, including acti... | |||
T8486 | GW6471 | GW 6471 | PPAR |
GW6471 is an antagonist of PPARα with IC50 of 0.24 μ M. GW6471 enhances the binding affinity of the PPAR α ligand-binding domain to the co-repressor proteins SMRT and NCoR. | |||
T3954 | Adelmidrol | NF-κB , COX , PPAR | |
Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid. | |||
T0061 | Clofibric acid | Chlorofibrinic acid | PPAR , Drug Metabolite |
Clofibric acid (Chlorofibrinic acid) is an antilipemic agent that is the biologically active metabolite of CLOFIBRATE. | |||
T2413 | FH535 | Wnt/beta-catenin , PPAR | |
FH535, a Wnt/β-catenin signaling and PPAR inhibitor, exhibits anti-tumor activities. | |||
T8780 | AMG131 | INT-131,AMG-131,CHS 131 | PPAR |
AMG131 (CHS 131) , is a novel, non-thiazolidinedione (TZD), selective peroxisome proliferator-activated receptor (PPAR)gamma modulator, which can be used for the treatment of type 2 diabetes mellitus (non-insulin depende... | |||
T21764 | MCC-555 | Isaglitazone,Netoglitazone | PPAR |
MCC-555 (Isaglitazone) is a PPARα and PPARγ agonist exerting antihyperglycemic effects. | |||
T0841 | Bezafibrate | BM15075 | PPAR |
Bezafibrate (BM15075) is an antilipemic agent that lowers CHOLESTEROL and TRIGLYCERIDES. It decreases LOW-DENSITY LIPOPROTEINS and increases HIGH-DENSITY LIPOPROTEINS. | |||
T21955 | GQ-16 | PPAR | |
GQ-16 is a partial agonist of PPARγ with a Ki of 160 nM. GQ-16 reduces adipogenic actions and promotes insulin Sensitization without weight gain. | |||
T9766 | GW590735 | PPAR | |
GW590735 is an effective and selective PPARα agonist with an EC50 of 4 nM on PPARα and at least 500-fold selectivity versus PPARδ and PPARγ. GW590735 can be used in dyslipidemia studies. | |||
T1149 | Fenofibrate | Procetofen,Lipanthyl,Lipantil | P450 , PPAR , Autophagy |
Fenofibrate (Lipanthyl) is a peroxisome proliferator receptor alpha agonist. Fenofibrate is a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic activity. | |||
T22708 | Darglitazone | CP-86325 | PPAR |
Darglitazone (CP-86325) is a potent, selective agonist of PPAR-γ with antidiabetic actions. Darglitazone is effective in controlling blood glucose and lipid metabolism. | |||
T1298 | Clofibrate | Clofibrato,Clofibratum,Ethyl clofibrate | PPAR |
Clofibrate (Clofibrato) is an aryloxyisobutyric acid derivate with antihyperlipidemic activity. | |||
T23389 | SR1664 | SR 1664 | PPAR |
SR1664 is a potent and selective PPARγ inhibitor with potential antidiabetic activity. SR1664 binds to PPARγ and potently inhibits Cdk5-mediated PPARγ phosphorylation (IC50 = 80 nM; Ki = 28.67 nM) without exhibiting PPAR... | |||
T4628 | Seladelpar | MBX 8025 | PPAR |
Seladelpar (MBX 8025) has been used in trials studying the treatment of Hyperlipidemia. | |||
T15821 | LY518674 | LY-674 | PPAR |
LY518674 (LY-674) decreases triglycerides and increases HDL-C and is used for the treatment of atherosclerosis. LY518674 is an effective and selective PPARα agonist (EC50: 42 nM for human PPARα). | |||
T2269 | Pirinixic Acid | Wy-14643,NSC 310038 | PPAR |
Pirinixic Acid (NSC 310038) is a synthetic thiacetic acid derivative used in biomedical research, carcinogenic Pirinixic acid is a peroxisome proliferator that activates specific peroxisome proliferator-activated recepto... | |||
T6829 | EPI-001 | EPI001,EPI 001 | Apoptosis , Androgen Receptor , PPAR |
EPI-001 is an androgen receptor N-terminal domain antagonist with IC50 of ~6 μM and a selective PPAR-gamma modulator. | |||
T9756 | AZD-9574 | PARP | |
AZD-9574 is a selective inhibitor of PARP1 at the sites of SSBs. AZD-9574 exhibits anti-cancer activities and can be used in studies about HRD+ breast cancer and advanced solid malignancies. | |||
T1402 | Fenofibric acid | Trilipix,FNF acid,NSC 281318 | MMP , COX , PPAR |
Fenofibric acid (FNF acid) is the active form of fenofibrate, a synthetic phenoxy-isobutyric acid derivate with antihyperlipidemic activity. | |||
T1415 | Gemfibrozil | CI-719,Jezil,Decrelip,Lopid | P450 , Adrenergic Receptor , PPAR |
Gemfibrozil (CI-719) interacts with peroxisome proliferator-activated receptors (PPARalpha) resulting in PPARalpha-mediated stimulation of fatty acid oxidation and an increase in lipoprotein lipase (LPL) synthesis. Gemfi... | |||
T13289 | EHP-101 | VCE-004.8 | Cannabinoid Receptor , HIF/HIF Prolyl-Hydroxylase , PPAR |
EHP-101 (VCE-004.8) is a specific dual agonist of PPARγ and CB2 receptor with potent anti-inflammatory activity. EHP-101 attenuates adipogenesis and prevents diet-induced obesity. | |||
T7821 | DG172 dihydrochloride | DG172 (dihydrochloride),DG-172 dihydrochloride | PPAR |
DG172 dihydrochloride (DG-172 dihydrochloride) is an antagonist of PPARβ/δ(IC50 : 27 nM). | |||
T8638 | NPC 15199 | FMOC-L-Leucine | Others |
NPC 15199 (FMOC-L-Leucine) is an anti-inflammatory agent. | |||
T15581 | Inolitazone | RS5444,Efatutazone,CS-7017 | PPAR |
Inolitazone (RS5444) a high-affinity PPARγ agonist. Inolitazone exhibits IC50 for growth inhibition is ~0.8 nM in vitro. | |||
T3941 | Choline Fenofibrate | Trilipix,ABT-335 | P450 , COX , PPAR |
Choline Fenofibrate (Trilipix) is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic activity. | |||
T16074 | Mifobate | SR-202 | PPAR |
Mifobate (SR-202) is a potent and specific antagonist of PPARγ. Mifobate shows antiobesity, antidiabetic and antiatherosclerotic effects[1]. | |||
T0214 | Pioglitazone | U 72107 | Ferroptosis , PPAR |
Pioglitazone (U 72107) is an insulin sensitizing agent and thiazolidinedione that is indicated for the treatment of type 2 diabetes. Pioglitazone has been linked to rare instances of acute liver injury. | |||
T3170 | Troglitazone | CS-045,Romozin,Rezulin,Romglizone,Noscal,Prelay | Apoptosis , Ferroptosis , PPAR , Autophagy |
Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity. | |||
T8505 | SC-236 | Sc 236 | Apoptosis , COX , PPAR |
SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively). | |||
T1622 | Rosiglitazone maleate | BRL 49653C,BRL 49653 | Ferroptosis , TRP/TRPV Channel , PPAR , Autophagy |
Rosiglitazone maleate (BRL 49653) is the maleate salt of rosiglitazone, an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity. | |||
T0509 | Cloxiquine | 5-Chloro-8-quinolinol,Dermofungin,Dermofongin | Antibacterial , Antibiotic , PPAR , Parasite , Antifungal |
Cloxiquine (Dermofongin) is a monohalogenated 8-hydroxyquinoline with activity against bacteria, fungi, and protozoa. | |||
T2260 | GW9662 | TIMTEC-BB SBB006523,GW 9662 | PPAR |
GW9662 (TIMTEC-BB SBB006523) is a specific PPARγ antagonist (IC50: 3.3 nM, in a cell-free assay), with 100 to 1000-fold functional selectivity for PPARγ than PPARα/δ in cells. | |||
T15453 | GW7647 | PPAR | |
GW7647 is a potent agonist of PPARα (EC50s: 6 nM, 1.1 μM, and 6.2 μM for human PPARα, PPARγ, and PPARδ, respectively). | |||
T6893 | MK-886 | MK886,L 663536 | Apoptosis , Leukotriene Receptor , COX , PPAR , FLAP |
MK-886 (L 663536) is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP). It is also a moderately potent PPARα antagonist. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
TN1693 | Glabrone | Influenza Virus , PPAR | |
Glabrone shows antiviral activity against influenza virus. | |||
T3867 | Alpinetin | (-)-alpinetin | BCL , PPAR |
Alpinetin ((-)-alpinetin) has antibacterial activity.Alpinetin has anti-inflammatory activity.Alpinetin can enhance the sensitivity of HepG2 hepatoma cells to the chemotherapeutic agent CDDP. Alpinetin has strong anti-he... | |||
T4S2128 | Bilobetin | PKA , PPAR | |
Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet. | |||
TN7060 | Methyl oleanonate | PPAR | |
3-Oxoolean-12-en-28-oic acid methyl ester is a triterpenoid PPARγ agonist isolated from Pistacia with anticancer properties. | |||
T2879 | Fisetin | TNF , Sirtuin , PPAR | |
Fisetin is a natural flavonol extracted from Rhus succedanea L that is structurally and functionally related to kaempferol, can modulate sirtuins,with antioxidant, anticancer, neuroprotection effects. | |||
T2985 | Gypenoside XLIX | PPAR | |
Extracted from whole herb of Gynostemsma pentaphyllum(Thunb.)Mak.;Store the product in sealed, cool and dry condition | |||
T2855 | Icariin | Ieariline | PDE , PPAR , Autophagy |
Icariin (Ieariline) is a flavonol glycoside, inhibiting PDE5 and PDE4 activities. Icariin also is a PPARα activator. | |||
T1238 | Daidzein | Isoflavone | Endogenous Metabolite , PPAR |
Daidzein (Isoflavone) is an isoflavone extract from soy, which is an inactive analog of the tyrosine kinase inhibitor genistein. It has antioxidant and phytoestrogenic properties. | |||
TN1018 | Angeloylgomisin H | PPAR | |
Angeloylgomisin H shows moderate cytotoxic activities with IC50 values ranging from 100 to 200 ug/mL against MCF7, HEK293 and CAL27 cell lines. | |||
T3362 | Eupatilin | NSC 122413 | PPAR , Autophagy |
Eupatilin (NSC-122413), a flavone derived from Artemisia princepsPampanini, is a PPARα agonist, with pharmacological activity. | |||
TN1990 | Norathyriol | Akt , DNA/RNA Synthesis , AMPK , PPAR | |
Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability. | |||
T4S1545 | Licarin B | (-)-Licarin B,Licarine B | transporter , Antibacterial , PPAR |
1.(-)-Licarin B (Licarine B) has anti-mycobacterial activity. | |||
T5S0788 | Oroxin A | Baicalein 7-O-glucoside | PPAR |
Oroxin A (Baicalein 7-O-glucoside) has antitussive and expectorant effects. | |||
T6917 | Oleuropein | Apoptosis , Aromatase , ROS , PPAR | |
Oleuropein is an antioxidant polyphenol isolated from olive leaf. | |||
T5S1550 | Cinnamyl alcohol | Cinnamic Alcohol,Styryl Carbinol | PPAR |
Cinnamyl alcohol (Styryl Carbinol) readily autoxidizes upon air exposure, and forms strong sensitizers as determined by the local lymph node assay. | |||
T5701 | OPHIOPOGONIN D | RAAS , Calcium Channel , NF-κB , PPAR | |
Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation. | |||
T12296 | Oleoylethanolamide | N-Oleoylethanolamide,Oleamide MEA,Oleic acid monoethanolamide | Endogenous Metabolite , PPAR |
Oleoylethanolamide (N-Oleoylethanolamide) is a high affinity endogenous agonist of PPAR-α. | |||
T3000 | Magnolol | NSC 293099,5,5'-Diallyl-2,2'-biphenyldiol | NF-κB , Retinoid Receptor , Antibacterial , PPAR , p53 , Autophagy |
Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks TNF-α-induced NF-KB activation. | |||
T3403 | Glabridin | Q-100692,KB-289522,LS-176045 | Reactive Oxygen Species , Tyrosinase , GABA Receptor , Antibacterial , PPAR |
Glabridin (KB-289522) may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS under high-glucose levels; may possess a therapeutic effect on... | |||
T1051 | Retinoic acid | Vitamin A acid,ATRA,all-trans-Retinoic acid,Tretinoin | Retinoid Receptor , PPAR , Endogenous Metabolite , Autophagy |
Retinoic acid (Tretinoin), a metabolite of vitamin A, is a natural agonist of the retinoic acid receptor RAR and inhibits RARα/β/γ (IC50=14 nM). Retinoic acid induces cellular differentiation, reduces cellular proliferat... | |||
T19500 | Palmitelaidic Acid | trans-Palmitoleic acid,9-trans-Hexadecenoic acid | Glucokinase , AMPK , PPAR |
Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue. | |||
T6S0117 | Avicularin | Fenicularin | ERK |
Avicularin (Fenicularin) has anti-allergic, anti-inflammatory, hepatoprotective, antioxidant, anti-tumor and other activities. It ameliorates human hepatocellular carcinoma by modulating the activities of NF-κB(p65), COX... | |||
T4S1173 | Agrimol B | Sirtuin , PPAR | |
1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb. | |||
TN3500 | Beta-Amyrone | β-Amyron | COX , AChR , PPAR , Antifection |
beta-Amyrone (β-Amyron) has antifungal activity against Chikungunya virus replication with an EC50 of 86 uM. beta-Amyrone has anti-inflammatory activity through inhibiting the expression of COX-2. beta-Amyrone exhibits a... | |||
T2S0633 | Raspberry ketone | Oxyphenalon,Rasketone,Aloenin,4-(4-Hydroxyphenyl)-2-butanone,p-Hydroxybenzyl acetone,Frambinone | PPAR |
1. Raspberry ketone (p-Hydroxybenzyl acetone) is cytotoxic to melanocytes through the binding of RK-derived quinones to thiol proteins and the pro-oxidant activity of the RK-oligomer, the exposure of human skin to RK can... | |||
T0646 | 5-Aminosalicylic Acid | Mesalazine,5-ASA,Mesalamine | NF-κB , Lipoxygenase , COX , Glutathione Peroxidase , Endogenous Metabolite , PAK , PPAR |
5-Aminosalicylic Acid (5-ASA) is an anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. | |||
TN1525 | Convallatoxin | NF-κB , P-gp , PPAR | |
Convallatoxin is a natural product | |||
T1633 | β-Carotene | Carotaben,Beta-Carotene,Provitamin A | Apoptosis , ROS , Endogenous Metabolite |
β-Carotene (Provitamin A) is a naturally-occurring retinol (vitamin A) precursor obtained from certain fruits and vegetables with potential antineoplastic and chemopreventive activities. As an anti-oxidant, beta carotene... | |||
T3138 | Astaxanthin | β-Carotene-4,4'-dione,Ovoester,AstaXin,AstaREAL,trans-Astaxanthin | Reactive Oxygen Species , PPAR |
Astaxanthin (trans-Astaxanthin) is a keto-carotenoid in the terpenes class of chemical compounds. It is classified as a xanthophyll but it is a carotenoid with no vitamin A activity. It is present in most red-colored aqu... | |||
T2932 | Ginsenoside Rh1 | Sanchinoside B2,Prosapogenin A2,20(S)-Ginsenoside Rh1,Sanchinoside Rh1 | IL Receptor , TNF , Endogenous Metabolite , PPAR , Interleukin |
Ginsenoside Rh1 (Sanchinoside B2) , one of the main constituents of Panax ginseng, exhibits anti-inflammatory effect. | |||
T14046 | Anandamide | (5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide | Cannabinoid Receptor , Endogenous Metabolite |
Anandamide ((5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide), an immune modulator, acts via not only cannabinoid receptors (CB1 and CB2) but also other targets (e.g., GPR18/GPR55) in the central nervous sy... | |||
T4S0800 | Demethyleneberberine | P450 , NOS , NF-κB , HIF , AMPK | |
Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria either in vitro or in vivo.Demethyleneberberine suppresses CYP2E1,... | |||
TN2601 | 12-O-Methylcarnosic acid | Reductase | |
12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from Salvia microphylla, is an active constituent of 5α-Reductase inhibition with an IC50 value of 61.7 μM. 12-O-Methylcarnosic acid has Antioxidant activity... | |||
T2915 | Bardoxolone | RTA 401,CDDO | Others , Nrf2 |
Bardoxolone (CDDO) is a synthetic oleanane triterpenoid that blocks the cellular synthesis of inducible nitric oxide synthase and inducible COX-2 in INF-γ-activated mouse macrophages with an IC50 value of 0.4 nM. By supp... | |||
T5S1172 | Tiliroside | Tribuloside | Antioxidant |
1. Tiliroside (Tribuloside) shows anticarcinogenic activity. 2. Tiliroside shows hepatoprotective activity. 3. Tiliroside shows antioxidant and anti-inflammatory activity, can inhibit neuroinflammation in neurodegenerati... | |||
TN4860 | Pueroside B | COX , PPAR | |
Pueroside B may can treat coronary heart disease, it can interact with two or more targets[peroxisome proliferator activated receptor γ (PPAR-γ), angiotensin-converting enzyme (ACE), hydroxymethylglutaryl coenzyme A rece... | |||
T81898 | Lyciumamide A | ||
DPP-IV-IN-5, derived from Lycium barbarum fruits, demonstrates moderate agonistic activity towards peroxisome proliferator-activated receptor (PPARγ), showing EC50 values between 10.09 and 44.26 μM, and exhibits inhibito... | |||
T75611 | Tibesaikosaponin V | ||
Tibesaikosaponin V (TKV), a triterpene diglycoside isolated from the methanol extract of Bupleurum chinense DC roots, effectively inhibits lipid accumulation and triacylglycerol content in adipocytes without inducing cyt... | |||
T83915 | Norbixin hydrate | ||
Norbixin, a carotenoid found in B. orellana, exhibits various biological activities including binding to the peroxisome proliferator-activated receptor γ (PPARγ) with a Ki of 1.15 µM in a cell-free assay. At a dosage of ... |
カタログ番号 | 製品名 | Species | Expression System |
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TMPY-02575 | PPAR gamma/PPARG Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
Peroxisome proliferator-activated receptor gamma (PPARG), a nuclear hormone receptor, plays a critical role in the lipid and glucose homeostasis, adipocyte differentiation, as well as intracellular insulin-signaling even... | |||
TMPY-06830 | PPAR alpha/PPARA Protein, Human, Recombinant (His) | Human | E. coli |
PPAR alpha/PPARA Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 31.36 kDa and the accession number is Q07869. | |||
TMPY-06837 | PPAR alpha/PPARA Protein, Mouse, Recombinant (His) | Mouse | E. coli |
PPAR alpha/PPARA Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 31.49 kDa and the accession number is P23204. | |||
TMPY-02481 | ACOX1 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Peroxisomal acyl-coenzyme A oxidase 1(ACOX1 or AOX) is the first enzyme of the fatty acid beta-oxidation pathway and belongs to the Acyl-CoA oxidase family. Human liver peroxisomes contain two acyl-CoA oxidases, namely, ... | |||
TMPY-03464 | ECH1 Protein, Human, Recombinant (His) | Human | E. coli |
ECH1 is a member of the hydratase/isomerase superfamily. ECH1 shows high sequence similarity to enoyl-CoA hydratases of several species, particularly within a conserved domain characteristic of these proteins. ECH1 con... | |||
TMPK-01329 | ANGPTL4 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Candidates for this common regulatory system include signals mediated by peroxisome proliferator-activated regulator and its response factor, angiopoietin-like 4. The expression and bioactivity of angiopoietin-like 4, an... | |||
TMPH-03711 | PPAR gamma Protein, Xenopus laevis, Recombinant (His) | Xenopus laevis | E. coli |
Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcript... | |||
TMPH-03755 | Ppard Protein, Human, Recombinant (His) | Human | E. coli |
Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosape... | |||
TMPJ-01213 | ASXL1 Protein, Human, Recombinant (GST) | Human | E. coli |
Putative Polycomb group protein ASXL1 involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma... | |||
TMPJ-00705 | BCAS2 Protein, Human, Recombinant (His, T7) | Human | E. coli |
Breast Carcinoma-Amplified Sequence 2 (BCAS2) is a member of the SPF27 family. BCAS2 is a nuclear protein and widely expressed in many rtissues. BCAS2 is identified as being overexpressed in various breast cancer cell li... | |||
TMPJ-00764 | Catalase/CAT Protein, Human, Recombinant | Human | E. coli |
Catalase (CAT) is a member of the catalase family. It exists as a homotetramer that occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Catalase ... | |||
TMPH-01855 | PEX19 Protein, Human, Recombinant (GST) | Human | E. coli |
Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacti... | |||
TMPY-03450 | GSTK1 Protein, Human, Recombinant | Human | E. coli |
GSTK1 gene encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. Glutathione S-transferases (GSTs) are a family of enzymes that catalyze a var... | |||
TMPY-03499 | CARHSP1 Protein, Human, Recombinant (His) | Human | E. coli |
CARHSP1 is a biomarker for diabetic complications. Adenovirus-mediated CARHSP1 overexpression and siRNA-mediated knockdown experiments were performed to characterize the role of CARHSP1 in the regulation of gluconeogen... |