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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T64348 | Antiproliferative agent-16 | Antiproliferative agent-16 | Others |
Antiproliferative agent-16 (Antiproliferative agent-16) is an indolyl hydrazide-hydrazone compound with anticancer activity. Antiproliferative agent-16 exhibits specificity toward breast cancer cells (IC50 of 6.94 μM for... | |||
T9974 | Antiproliferative agent-13 | Dehydrogenase | |
Antiproliferative agent-13 is a compound with antiproliferative activity. | |||
T64391 | Antiproliferative agent-15 | Others | |
Antiproliferative agent-15 is a reagent with anticancer activity. Antiproliferative agent-15 showed antiproliferative activity against human colon cancer (HCT116 and HCT15) and brain cancer (LN-229 and GBM-10). | |||
T83021 | Antiproliferative agent-36 | Others | |
Antiproliferative agent-36 is a broad-spectrum anticancer benzothiazolylhydrazone-derived compound that inhibits cell proliferation. | |||
T60129 | MT189 | Antiproliferative agent-14 | Microtubule Associated |
MT189 (Antiproliferative agent-14) is a potent tubulin polymerization inhibitor, with an IC50 of 3.41 μM. Antiproliferative agent-14 has excellent antiproliferative activity. Antiproliferative agent-14 possess the abilit... | |||
T83015 | Antiproliferative agent-42 | ||
Antiproliferative Agent-42 (Compound 7m), a dihydrodipyrrolo compound, exhibits antiproliferative activity against the Panc-1 cell line, with an IC 50 of 12.54 μM [1]. | |||
T72200 | Antiproliferative agent-11 | ||
Antiproliferative Agent-11, a selective Ruthenium(II)-Tris-pyrazolylmethane complex, exhibits antiproliferative effects on MCF-7, HeLa, 518A2, HCT116, and RD cancer cell lines with IC50 values of 6, 10, 6.8, 6.7, and 6 μ... | |||
T83019 | Antiproliferative agent-38 | ||
Antiproliferative Agent-38 (COM 18), a tetracyclic compound, features a reactive ring nitrogen (likely the quinoline moiety) that resists N-alkylation. Despite its classification, it neither exhibits anti-malarial proper... | |||
T83022 | Antiproliferative agent-33 | ||
Antiproliferative Agent-33 (Compound 2g) serves as an anti-proliferative, antifungal, and antibacterial agent, effectively inhibiting the proliferation of MDA-MB-231 cells (IC50: 16.38 μM), impairing the growth of gram-n... | |||
T79332 | Antiproliferative agent-32 | Apoptosis | |
Antiproliferative agent-32 (Compound 1c) impedes phosphorylation within the PI3K/Akt/mTOR signaling pathway, restrains proliferation of Huh7 and SK-Hep-1 cells, induces apoptosis, and inflicts mitochondrial damage, rende... | |||
T79368 | Antiproliferative agent-34 | EGFR | |
Antiproliferative Agent-34 (Compound A14), a multitarget kinase inhibitor, demonstrates IC50 values of 177 nM for EGFR L858R/T790M and 1567 nM for EGFR WT. Additionally, it inhibits JAK2, ROS1, FLT3, FLT4, and PDGFRα wit... | |||
T75014 | Antiproliferative agent-18 | ||
Compound 5k (Antiproliferative Agent-18) is an antiproliferative agent that exhibits moderate antibacterial and antifungal activities [1]. | |||
T63864 | Antiproliferative agent-4 | ||
Antiproliferative agent-4 showed good anti-proliferative effects on some cancer cells. antiproliferative agent-4 inhibited tumour growth in nude mice and showed low toxicity. antiproliferative agent-4 reduced the mitocho... | |||
T60555 | Antiproliferative agent-3 | ||
Antiproliferative agent-3 (comp 4) exhibits potent growth inhibitory effects against MCF-7 cells with IC 50 of 0.19 nM [1]. | |||
T83020 | Antiproliferative agent-37 | ||
Antiproliferative agent-37 (compound 10J) inhibits cell proliferation by arresting cells at the G2/M phase of the cell cycle [1]. | |||
T79322 | Antiproliferative agent-30 | ||
Antiproliferative agent-30 (Compound 8g) demonstrates broad-spectrum antiproliferative activity, with IC50 values of 0.054 nM, 0.008 nM, and 0.144 nM against HCT-116, K562, and MV-4-11 cancer cell lines, respectively. It... | |||
T74921 | Antiproliferative agent-12 | ||
Antiproliferative Agent-10 (Compound 1), a ruthenium(II)-tris-pyrazolylmethane complex, functions as an anti-tumor agent by impeding cancer cell proliferation through the inhibition of mitochondrial calcium uptake [1]. | |||
T83023 | Antiproliferative agent-26 | ||
Antiproliferative agent-26 (compound 4g) exhibits a broad spectrum of activity against leukemia, CNS cancers, melanoma, renal, and breast cancers at a concentration of 10 μM. It hinders colony formation and induces cell ... | |||
T74844 | Antiproliferative agent-23 | ||
Antiproliferative agent-23, a microtubule-destabilizing agent (MDA), disrupts the tubulin-microtubule system, leading to apoptosis through a mitochondrion-dependent pathway. This involves downregulation of Bcl-2 protein,... | |||
T62012 | Antiproliferative agent-8 | ||
Antiproliferative agent-8 (Compound 5a) is an anti-cancer compoundwith antiproliferative activity. Antiproliferative agent-8 can significantly increase the P53 levels. | |||
T83016 | Antiproliferative agent-41 | ||
Antiproliferative Agent-41 (Compound 14), classified as indanorine [1], functions as an antiproliferative compound. | |||
T61996 | Antiproliferative agent-6 | ||
Antiproliferative agent-6 (compound 8a) is a potent antitumor compound. Antiproliferative agent-6 shows antiproliferative activity. Antiproliferative agent-6 inhibits cancer cell lines HCT116, MCF-7, H460 and non-tumor a... | |||
T64212 | Antiproliferative agent-5 | ||
Antiproliferative agent-5 (compound 4o) irreversibly and significantly inhibits the proliferation of gastric cancer cells. antiproliferative agent-5 blocks the cell cycle in G2/M phase, induces ROS accumulation and activ... | |||
T72191 | Antiproliferative agent-20 | ||
Antiproliferative Agent-20 is a potent, orally active anticancer compound exhibiting both antiproliferative and anti-angiogenic activities. | |||
T62549 | Antiproliferative agent-7 | ||
Antiproliferative agent-7 (compound 8f) is a potent anti-proliferative agent. Antiproliferative agent-7 can promote ROS production and induce apoptosis. | |||
T72205 | Antiproliferative agent-19 | ||
Antiproliferative Agent-19, an anti-cancer compound, demonstrates antiproliferative effects by inducing apoptosis in lung cancer cells and causing cell cycle arrest in the G2/M phase. | |||
T79289 | Antiproliferative agent-27 | Apoptosis | |
Antiproliferative Agent-27 (Compound 11) is a notable antiproliferative agent that markedly diminishes tumor cell colony formation and induces apoptosis, demonstrating potential for utilization in cancer research [1]. | |||
T72204 | Antiproliferative agent-17 | ||
Antiproliferative Agent-17 exhibits both antimicrobial properties against Gram-positive bacteria and anticancer activity [1]. | |||
T72199 | Antiproliferative agent-10 | ||
Antiproliferative Agent-10, a ruthenium(II)-tris-pyrazolylmethane complex, functions as an anti-tumor compound by impeding cancer cell growth through the inhibition of mitochondrial calcium uptake. | |||
T83018 | Antiproliferative agent-39 | ||
Antiproliferative Agent-39 (Compound 12) effectively inhibits the proliferation of various cancer cell lines, including A549, SNU-638, Col2, HT1080, and MCF-7, with respective IC50 values of 11, 25, 14, 11, and 6.3 μM [1... | |||
T79275 | Antiproliferative agent-25 | Histone Methyltransferase | |
Antiproliferative Agent-25 (Compound 3s4) is a selective PRMT5 inhibitor displaying an IC50 of 0.11 μM. It elevates hnRNP E1 protein levels and forms hydrogen bond interactions with SAM and the E444 residue of PRMT5. Thi... | |||
T83017 | Antiproliferative agent-40 | ||
Antiproliferative agent-40 (Compound 9) effectively inhibits the proliferation of HT1080 and MCF-7 cancer cells, displaying IC50 values of 52 μM and 8.2 μM, respectively [1]. | |||
T1892 | Kobe2602 | Raf , Ras | |
Kobe 2602 is an inhibitor of Ras that exhibits anticancer chemotherapeutic activities. | |||
T7538 | Tetraethylammonium chloride | Potassium Channel | |
Tetraethylammonium chloride is a quaternary ammonium compound. It is a non-selective potassium channel blocker. It is a good substrate for organic cation transporter proteins and has antitumor properties. | |||
T40168 | DHODH-IN-16 | Dehydrogenase | |
DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human). | |||
T7969 | Dipyrithione | Others | |
Dipyrithione appears to have novel cytotoxicity and potent broad-spectrum antitumor activity | |||
T1349 | 5-Fluorouridine | Others , DNA/RNA Synthesis | |
5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine. 5-fluorouridine is a solid. This compound belongs to the pyrimidine nucleosides and analogues. These are compound... | |||
T38889 | Thailanstatin A | ||
Thailanstatin A is an ultra-potent inhibitor of eukaryotic RNA splicing (IC50 =650 nM). Thailanstatin A inhibits multiple cancer cell lines via non-covalent binding to the SF3b subunit of the U2 snRNA subcomplex of the s... | |||
TP2207 | Pasireotide Acetate | Somatostatin | |
Pasireotide Acetate is a stable cyclohexapeptide somatostatin mimic | |||
T9880 | ZINC05007751 | MAPK | |
ZINC05007751 is an effective inhibitor of NIMA-related kinase NEK6 (IC50 = 3.4 μM). ZINC05007751 is very selective against NEK1 and NEK6 with no significant activity observed against NEK2, NEK7, and NEK9. | |||
T9117 | BSJ-4-116 | CDK , PROTACs | |
BSJ-4-116 is a highly potent and selective CDK12 degrader (PROTAC) with an IC50 of 6 nM. It downregulates DDR genes through a premature termination of transcription, primarily through increasing poly(adenylation). | |||
T21679 | 4'-bromo-Resveratrol | Sirtuin | |
4'-bromo-Resveratrolis a potent inhibitor of the deacetylases sirtuin 1 (SIRT1) and 3 (SIRT3) | |||
T15648 | KDM5-C70 | Histone Demethylase | |
KDM5-C70 is an ethyl ester derivative of KDM5-C49. KDM5-C70 is an effective, cell-permeable, and pan-KDM5 histone demethylase inhibitor. KDM5-C70 has an antiproliferative effect in myeloma cells, inducing a genome-wide e... | |||
T9196 | IACS-13909 | BBP-398 | Phosphatase |
IACS-13909 (BBP-398), a specific and potent allosteric inhibitor of SHP2, that suppresses signaling through the MAPK pathway. | |||
T14141 | AGI-24512 | Others , Methionine Adenosyltransferase (MAT) | |
AGI-24512 is a inhibitor of methionine adenosyltransferase 2A (MATA2 ).It is useful for treatment of cancer and blocks growth of MTAP-deleted cancer cells in vitro. | |||
T13336 | VTP50469 | Apoptosis , Epigenetic Reader Domain , Histone Methyltransferase | |
VTP50469 is a highly selective and orally active inhibitor of Menin-MLL interaction( Ki: 104 pM) and has potently anti-leukemia activity. | |||
T1753 | D-64131 | Microtubule Associated | |
D-64131 is a tubulin polymerization inhibitor with an IC50 value of 0.53 μM. | |||
T8478 | SC-43 | Apoptosis , Phosphatase , STAT | |
SC-43 is a potent and orally active agonist of SHP-1 (PTPN6). SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis, and with anti-fibrotic and anticancer effects. | |||
T15012 | Crolibulin | EPC2407 | Microtubule Associated |
Crolibulin (EPC2407) is an inhibitor of small molecule tubulin polymerization. | |||
T2451 | GlyH-101 | GlyH 101 | CFTR , Autophagy |
GlyH-101 is a cell-permeable glycinyl hydrazone compound that blocks CFTR with Ki of 1.4 uM. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T10668 | Camalexin | Reactive Oxygen Species , ROS , Antibacterial , Antifungal | |
Camalexin is a phytoalexin isolated from Camelina sativa. It has antifungal, antibacterial, antiproliferative, and anticancer activities. Camalexin can induce ROS production. | |||
TN7041 | (-)-Epipodophyllotoxin | Apoptosis | |
(-)-Epipodophyllotoxin (2) is an antiproliferative agent against cancer cells with GI50s of 0.36 and 0.24 μM in HeLa cells and MCF-7 cells, respectively. (-)-Epipodophyllotoxin can inhibit mitotic spindle assembly in vit... | |||
T5808 | (-)-Oxypeucedanin hydrate | OXYPEUCEDANIN HYDRATE | Others |
(-)-Oxypeucedanin hydrate is a furanocoumarin. It has a role as a metabolite. | |||
T7052 | Gnetol | Tyrosinase , COX , HDAC , AChR | |
Gnetol competitivity inhibits butyrylcholinesterase (IC50: 1.3 uM). Gnetol has a strong inhibitory effect on murine tyrosinase activity. Gnetol significantly suppresses melanin biosynthesis in murine B16 melanoma cells. ... | |||
TN2069 | Picrocrocin | Apoptosis | |
Picrocrocin is a natural product | |||
T6830 | Epoxomicin | BU-4061T,BU-4061T,Aids010837 | Apoptosis , Proteasome |
Epoxomicin (BU-4061T,Aids010837) is a selective proteasome inhibitor with anti-inflammatory activity, inhibits primarily the CH-L activity of the 20S proteasome, while T-L and PGPH catalytic activities are also inhibited... | |||
T9605 | Sangivamycin | BA-90912,NSC 65346 | Nucleoside Antimetabolite/Analog , PKC |
Sangivamycin (NSC-65346) is an effective inhibitor of protein kinase C (PKC, Ki = 10 μM). Sangivamycin exhibits antiproliferative activity against a variety of human cancers. | |||
T19676 | Tributyrin | NSC661583,NSC 661583,NSC-661583 | Apoptosis |
Tributyrin (Glyceryl tributyrate), a neutral short-chain fatty acid triglyceride, is a stable and rapidly absorbed prodrug of Butyric Acid. Tributyrin diffuses through biological membranes and is metabolized by intracell... | |||
T34394 | Rotenolone | Rotenolone I,12alpha-HYDROXYROTENONE | Others |
Rotenolone (12alpha-HYDROXYROTENONE) is a metabolite of Rotenone which is a natural compound derived from plants of the genera Derris and Lonchocarpus. | |||
TN4569 | Minimolide F | Others | |
Minimolide F, isolated from Centipeda minima, shows antiproliferative activity against human nasopharyngeal cancer cells with an IC50 of 17.4 μM. | |||
T4957 | Carnosic acid | Apoptosis , ROS , Antibacterial | |
Carnosic acid is a lipid absorption inhibitor, endowed with antioxidative, antimicrobial, photoprotective potential, and antiproliferative properties. | |||
T7032 | Eupatorin | Others , P450 | |
Eupatorin has antiproliferative and antiangiogenic effects. Eupatorin has antiproliferative and cytostatic effects on MDA-MB-468 human breast cancer cells due to CYP1-mediated metabolism. Eupatorin-induced cell death is ... | |||
T0036 | 18β-Glycyrrhetinic acid | Enoxolone,Glycyrrhetin | Dehydrogenase , Endogenous Metabolite |
18β-Glycyrrhetinic acid (Enoxolone) is the major bioactive component of Glycyrrhizae Radix and possesses anti-ulcerative, anti-inflammatory and antiproliferative properties. | |||
T4373 | Brassinin | BSN | Antifungal |
Brassinin (BSN) (BSN) is a phytoalexin isolated from B. campestris that exhibits anticancer, chemopreventative, antiproliferative, and antifungal activities. | |||
TC0039 | Vasicinone | Others | |
Vasicinone may act as a hepatoprotective agent. (±)-Vasicinone has significant antitussive, expectorant, and bronchodilating activities, which can be used to treat respiratory disease.(S)-Vasicinone exhibits antiprolifer... | |||
TN1933 | Mitraphylline | IL Receptor , TNF , NF-κB | |
Mitraphylline has antiproliferative effects on human glioma and neuroblastoma cell lines. It also has anti-inflammatory activity, it inhibits lipopolysaccharide-mediated activation of primary human neutrophils. | |||
T7174 | Urolithin A | Apoptosis , Reactive Oxygen Species , DNA/RNA Synthesis , Endogenous Metabolite , Autophagy , Drug Metabolite | |
Urolithin A is a secondary metabolite of ellagic acid, a polyphenolic antioxidant, that has antiproliferative, anti-inflammatory, and anti-oxidant properties. | |||
TN1675 | Gardenin B | Apoptosis , ROS , Caspase , NO Synthase | |
Gardenin B exhibits superior antiproliferative activity against lung, breast, colon, hepatic and leukaemia cell lines as well as in keratinocytes . | |||
T3408 | Syringin | Lilacin,Syringoside,eleutheroside-b,Methoxyconiferine | NOS , Autophagy |
Syringin (eleutheroside-b) is a compound with antitumor, antiproliferative, immunomodulatory and platelet aggregation inhibiting effects. | |||
T2212 | Geniposide | Beta Amyloid , Influenza Virus | |
Geniposide is an iridoid glycoside with a variety of biological activities including neuroprotective, anti-diabetic, antiproliferative, and antioxidative activity. Geniposide has been shown to regulate Nrf2 translocation... | |||
TN1260 | 3-O-beta-D-Glucopyranosylplatycodigenin | Others | |
3-O-beta-D-Glucopyranosylplatycodigenin is isolated from the roots of Platycodon grandiflorum. | |||
T3916 | Ginsenoside F2 | Apoptosis , Endogenous Metabolite , Autophagy | |
Ginsenoside F2 has antiproliferative activity against breast cancer stem cells (CSCs). It induces apoptosis in breast CSCs by activating the intrinsic apoptotic pathway and mitochondrial dysfunction. | |||
T36430 | Pheophorbide a | ||
Pheophorbide a is a product of chlorophyll breakdown that has been used as a photosensitizer in photodynamic therapy for the treatment of cancer. It has been reported to inhibit U87MG cells with an IC50 value of 2.8 μg/m... | |||
T6102 | 2'-acetylacteoside | Antioxidant , Reductase | |
2'-Acetylacteoside has antioxidative activity. It can significantly attenuate glutamate-induced neurotoxicity at concentrations ranging from 0.1 to 10 μM. 2'-Acetylacteoside shows antiproliferative effects on aortic smoo... | |||
T6S0052 | Chelerythrine | Toddalin,Broussonpapyrine,Cheleritrine | Apoptosis , BCL , PKC , Autophagy |
1. Chelerythrine (Broussonpapyrine) may have antimanic effect . 2. Chelerythrine can inhibit telomerase activity. 3. Chelerythrine is a well-known protein kinase C inhibitor . 4. Chelerythrine has potential antiprolifera... | |||
T4S2164 | Narirutin | Naringenin-7-O-rutinoside,Isonaringin | Others , Antibacterial |
1. Narirutin (Naringenin-7-O-rutinoside) has antiproliferative property. 2. Narirutin has anti-oxidant property. 3. Narirutin has anti-allergic and anti-inflammatory properties , can reduce airway inflammation in ovalbum... | |||
T2869 | Emodin | Frangula emodin | SARS-CoV , Casein Kinase , Autophagy |
Emodin (Frangula emodin) is a naturally occurring anthraquinone present in the roots and barks of numerous plants; exerts antiproliferative effects in Y cells that are regulated by different signaling pathways. | |||
T0610 | Piceatannol | trans-Piceatannol,Astringenin | Apoptosis , Serine/threonin kinase , PKA , Syk , PKC , Autophagy |
Piceatannol (Astringenin) is an anti-inflammatory, immunomodulatory and antiproliferative agent. It inhibits p56lck and syk protein tyrosine kinases and inhibits NF-κB activation and gene expression of TNF-induced. It is... | |||
T3404 | Cucurbitacin B | Cuc B,DATISCACIN,Amarine | Apoptosis , PTEN , Integrin , Endogenous Metabolite , HIF , STAT , Autophagy |
Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells. It inhibited AKT signaling activation through up-regulation of PTEN. Cucurbitacin B is an effective inh... | |||
T2821 | Ethyl ferulate | Ethyl 4'-hydroxy-3'-methoxycinnamate,Ethyl 3-(4-hydroxy-3-methoxyphenyl)acrylate,Ferulic acid ethyl ester | Reactive Oxygen Species |
Ethyl ferulate (Ethyl 4'-hydroxy-3'-methoxycinnamate) is the alkyl ester derivative of ferulic acid which is a naturally occurring plant product with anti-oxidative, anti-inflammatory, neuroprotective, and antiproliferat... | |||
T14305 | Apicidin | OSI 2040 | Apoptosis , HDAC , Autophagy |
Apicidin (OSI 2040) is a histone deacetylase (HDAC) inhibitor with antiparasitic activity and antiproliferative activity.Apicidin attenuates memory deficits, inhibits cell growth and proliferation, and induces apoptosis ... | |||
T0795 | Rutin | Quercetin 3-O-rutinoside,Rutoside | Beta Amyloid , Prostaglandin Receptor , Autophagy |
Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic properties. | |||
T75643 | Isoxanthohumol | HSV | |
Isoxanthohumol is a prenylated flavonoid derived from hops and beer with antiproliferative activity against several human cancer cell lines.Isoxanthohumol inhibits the metastasis or invasion of lung metastases of tumor c... | |||
T3S1967 | (S)-Indoximod | N-ME-Tryptophan,Abrine,L-Abrine | Others , Indoleamine 2,3-Dioxygenase (IDO) |
(S)-Indoximod (L-Abrine) exhibits inhibition of rabbit small intestine indoleamine 2, 3-dioxygenase, competitive inhibition of IDO, reduction of Foxp3 protein expression in tumor of C57BL/6 mouse allografted with mouse L... | |||
T2P2806 | Hederacolchiside A1 | Raddeanoside R13 | Apoptosis , ERK , MEK , Akt , PI3K , Parasite , mTOR |
Hederacolchiside A1 (Raddeanoside R13) shows anti-leishmanial activity, it exhibits a strong antiproliferative activity on all stages of development of the parasite by altering membrane integrity and potential. Hederacol... | |||
T4S1637 | Gamma-Mangostin | Normangostin | Others , 5-HT Receptor |
1. gamma-Mangostin (Normangostin) as a preventive agent of the metabolic syndrome. 2. Gamma-Mangostin has free radical scavenging activity, and antiproliferative and apoptotic activity in HepG2 cells. 3. Gamma-Mangostin ... | |||
TMS0418 | Dihydroergotoxine mesylate | Ergoloid mesylates | GABA Receptor |
Dihydroergotoxine mesylate (Ergoloid mesylates) is mainly used to improve symptoms and physical symptoms of mental degeneration related to aging. | |||
TN6637 | Gardenin D | ||
Gardenin D has antioxidant, and antiproliferative activities. | |||
T12403 | Penitrem A | Others | |
Penitrem A is a selective antagonist of BK channel with antiproliferative and anti-invasive activities against multiple malignancies. | |||
TN3247 | 7-O-Prenylscopoletin | PLK , CDK | |
7-O-Prenylscopoletin and cedrelopsin show high antiproliferative activities against cancer cell lines. | |||
T81794 | Micromonosporamide A | ||
Micromonosporamide A demonstrates antiproliferative activity contingent upon glutamine presence. | |||
T38890 | Thailanstatin C | ||
Thailanstatin C, an antiproliferative agent derived from Burkholderia thailandensis MSMB43, functions as a potent inhibitor of pre-mRNA splicing (IC50 = 6.84 μM). | |||
T17270 | Yatein | Others | |
Yatein inhibits herpes simplex virus type 1 replication by interruption the immediate-early gene expression. Yatein is a lignan isolated from A. chilensis. It also has antiproliferative activity. | |||
T81996 | Kadsuphilin A | ||
Kadsuphilin A, extracted from Kadsura coccinea (Lem.), exhibits weak antiproliferative activity [1]. | |||
TN4629 | Nemoralisin C | Others | |
Nemoralisin C shows antiproliferative activity against HepG2, AGS, MCF-7, and A-549 cancer cell lines. | |||
T38891 | Valeriandoid F | ||
Valeriandoid F, an iridoid, exhibits potent inhibition of nitric oxide (NO) production with an IC50 value of 0.88 μM. Additionally, Valeriandoid F possesses anti-inflammatory and antiproliferative properties. | |||
TN1942 | Momordicoside F1 | Others | |
Momordicoside F1 may have antiproliferative activities against MCF-7, WiDr, HEp-2, and Doay human tumor cell lines. | |||
TN1988 | Nephthenol | Others | |
Nephthenol shows antiproliferative activity against the cell lines HUVEC and K-562 and for cytotoxicity against the cell line HeLa. | |||
TN1810 | Jatropholone B | Others | |
Jatropholone B shows antiproliferative activity against cancer cell lines. It also has gastroprotective activity in preventing the gastric lesions in mice. | |||
TN6591 | Cannabisin B | ||
Cannabisin B possesses considerable antiproliferative activity and that it may be utilised as a promising chemopreventive agent against hepatoblastoma disease. It induces autophagic cell death by inhibiting the AKT/mTOR ... | |||
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カタログ番号 | 製品名 | Species | Expression System |
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TMPH-01073 | CD81 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
CD81 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 25.8 kDa and the accession number is P60033. | |||
TMPY-06983 | IFN gamma Protein, Human, Recombinant (E. coli) | Human | E. coli |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ... | |||
TMPH-02451 | IFN gamma Protein, Marmota monax, Recombinant (His) | Marmota monax | P. pastoris (Yeast) |
Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproli... | |||
TMPH-00373 | IFN gamma Protein, Chicken, Recombinant (GST) | Chicken | E. coli |
Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproli... | |||
TMPK-00889 | IFNAR2 Protein, Human, Recombinant (aa 27-243, His) | Human | HEK293 Cells |
Although interferon (IFN)-α is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-α-regulated... | |||
TMPK-00637 | IFNAR2 Protein, Cynomolgus, Recombinant (aa 27-243, His) | Cynomolgus | HEK293 Cells |
Although interferon (IFN)-α is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-α-regulated... | |||
TMPJ-01371 | Limitin Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Limitin, also called IFN-ζ, is a secreted interferon (IFN)-like glycoprotein. Limitin has approximately 30% sequence homology with IFN-α, IFN-β, and IFN-ω and binds to the IFN-α/β receptors. Like IFN-α and IFN-β, limitin... | |||
TMPY-02122 | IFNGR2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Interferon-gamma receptor beta chain (IFNgammaR2), also known as IFNGR2, belongs to the type II cytokine receptor family, whose deficiency is a cause of autosomal recessive mendelian susceptibility to mycobacterial disea... |