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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T19051 | Reactive Blue 4 | Others | |
Reactive Blue 4 is an anthraquinone dye with phytotoxic, cytotoxic, and genotoxic. It is a single colorimetric chemosensor for the sequential determination of multiple analytes with different optical responses in aqueous... | |||
TP1676L | C-Reactive Protein (CRP) 201-206 acetate | C-Reactive Protein (CRP) 201-206 acetate(130348-99-1 free base) | Others |
C-Reactive Protein (CRP) 201-206 acetate (C-Reactive Protein ) is the 201-206 fragment of C-Reactive Protein. C-Reactive Protein (CRP) acetate, the prototypic marker of inflammation, is a cardiovascular risk marker and m... | |||
TP1592L | C-Reactive Protein (CRP) 174-185 acetate | C-Reactive Protein (CRP) 174-185 acetate(160369-86-8 free base) | Others |
C-Reactive Protein (CRP) 174-185 acetate is an acute phase serum protein synthesized in response to inflammatory cytokines, produces antitumor effects in animals. The fragment CRP (174-185) (RS-83277) shows similar activ... | |||
TP1516L | C-Reactive Protein (CRP) 77-82 acetate | C-Reactive Protein (CRP) 77-82 acetate(130349-01-8 free base) | Others |
C-Reactive Protein (CRP) 77-82 acetate is the 77-82 fragment of C-Reactive Protein. C-Reactive Protein (CRP), the prototypic marker of inflammation, is a cardiovascular risk marker and may promote atherogenesis.C-reactiv... | |||
TP1676 | C-Reactive Protein (CRP) (201-206) | C-Reactive Protein (CRP) 201-206 | Others |
C-Reactive Protein (CRP) Fragment (201-206) is a peptide segment derived from C-Reactive Protein (CRP), the quintessential indicator of inflammation. As a cardiovascular risk marker, CRP may facilitate atherogenesis. | |||
TP1592 | C-Reactive Protein (CRP) (174-185) | C-Reactive Protein (CRP) 174-185 | |
CRP, an acute phase serum protein synthesized in response to inflammatory cytokines, produces antitumor effects in animals. The fragment CRP (174-185) (RS-83277) shows similar activity by significantly enhancing the tumo... | |||
TP1516 | C-Reactive Protein (CRP) (77-82) | C-Reactive Protein (CRP) 77-82 | |
C-Reactive Protein (CRP) 77-82 is the 77-82 fragment of C-Reactive Protein. C-Reactive Protein (CRP), the prototypic marker of inflammation, is a cardiovascular risk marker and may promote atherogenesis.C-reactive protei... | |||
T35575 | Aldehyde Reactive Probe (trifluoroacetate salt) | ||
DNA is continually damaged by endogenous and environmental agents leading to the formation of abasic (apurinic/apyrimidinic, AP) sites that are disruptive to DNA synthesis. Aldehyde Reactive Probe (ARP) is a biotinylated... | |||
T64813 | Reactive Blue 19 | ||
Reactive Blue 19 is a useful organic compound for research related to life sciences. The catalog number is T64813 and the CAS number is 2580-78-1. | |||
T83952 | CoraFluor 1, amine reactive | ||
CoraFluor 1, an amine-reactive terbium-based compound, serves as a potent donor in time-resolved Förster resonance energy transfer (TR-FRET) assays, including applications in target engagement and ternary complex assessm... | |||
T19049 | Procion Blue HB | Reactive Blue 2 | Others |
Procion Blue HB is an antagonist of purinergic. | |||
T16951 | Sulcotrione | Reactive Oxygen Species | |
Sulcotrione is a β-triketone herbicide. It also can inhibit hydroxyphenylpyruvate dioxygenase. | |||
TP1344 | Luciferase | Others | |
Luciferase is a flavin-dependent monooxygenase found in bioluminescent bacteria. Luciferase is an invaluable tool for identifying and characterizing functional variants, allowing investigations of gene expression, intrac... | |||
T5426 | DMNQ | Reactive Oxygen Species , ROS | |
DMNQ is a 1,4-naphthoquinone that acts as a redox-cycling agent, typically increasing intracellular superoxide and hydrogen peroxide formation.DMNQ increases ROS generation | |||
T1710 | Trolox | Apoptosis , Antioxidant , Ferroptosis , Reactive Oxygen Species | |
Trolox is a vitamin E analogue, used in reducing oxidative stress or damage. | |||
T15030 | CycLuc1 | Others | |
CycLuc1 is a brain penetrant luciferase substrate. CycLuc1 may be a superior BLI substrate as compared to D-luciferin for monitoring tumor growth of intracranial GBM xenografts. | |||
T3496 | Buprofezin | NNI 750,Applaud,Buprofezine | Reactive Oxygen Species |
Buprofezin (Applaud) is an insecticide used for control of insect pests such as mealybugs, leafhoppers and whitefly on vegetable crops. | |||
T3952 | TPEN | TPEDA | Apoptosis , Reactive Oxygen Species , Autophagy |
TPEN (TPEDA) is a specific cell-permeable heavy metal chelator. | |||
T5116 | Iprodione | Others , Reactive Oxygen Species , Antifungal | |
Iprodione is a fungicide. Iprodione is also used in cannabis testing kits as a component of pesticide mixes. | |||
T5966 | Hexaconazole | (-)-Hexaconazol | Reactive Oxygen Species , Antifungal |
Hexaconazole ((-)-Hexaconazol) is a broad-spectrum triazole fungicide that inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14α-demethylation of lanosterol, which results in disruption of ... | |||
T19428 | Mito-TEMPO | Reactive Oxygen Species , Mitochondrial Metabolism | |
Mito-TEMPO is a mitochondria-targeted superoxide dismutase mimetic. Mito-TEMPO scavenges superoxide and alkyl radicals and prevents mitochondrial oxidation, necrosis and apoptosis. | |||
T5518 | N-acetylcysteine amide | Reactive Oxygen Species , ROS | |
N-Acetylcysteine amide is a thiol antioxidant and neuroprotective agent that can permeate cell membranes and the blood-brain barrier. | |||
T4168 | Visomitin | SKQ1 | Reactive Oxygen Species |
Visomitin (SKQ1) is a mitochondria-targeted antioxidant that decreases transmembrane potential and production of reactive oxygen species (ROS). | |||
T8370 | GSK5182 | Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Reactive Oxygen Species | |
GSK5182 is a highly selective inverse estrogen-related receptor γ agonist (IC50 : 79 nM) | |||
T7703 | PK11007 | Reactive Oxygen Species , p53 | |
PK11007 is an anti-p53 drug. | |||
T15433 | GSK2795039 | Apoptosis , Reactive Oxygen Species , ROS , NADPH | |
GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption. GSK2795039 decreases apoptosis. GSK2795039 is an inhibitor of NADPH oxidase 2 (NOX2) (pIC50: 6 in different cell-free assays). | |||
T38155 | N-Acetyl-D-cysteine | Reactive Oxygen Species | |
N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group. | |||
T2090 | Lexibulin | CYT-997 | Apoptosis , Reactive Oxygen Species , Microtubule Associated |
Lexibulin (CYT-997)(CYT-997) is a potent tubulin polymerization inhibitor (IC50: 10-100 nM, in Y cell lines). Lexibulin blocks the formation of the mitotic spindle and leading to cell cycle arrest at the G2/M phase; this... | |||
T13189 | TP-10 | PDE | |
T0756 | Ethoxyquin | Santoquin,Quinol,Santoflex | HSP , Reactive Oxygen Species |
Ethoxyquin (Santoflex) is an antioxidant used in animal feeds. | |||
T0418 | Allylthiourea | N-Allylthiourea,Thiosinamine | MAO , Reactive Oxygen Species |
Allylthiourea (Thiosinamine), a metabolic inhibitor, specifically suppresses ammonia oxidation. | |||
T17250 | W-54011 | ROS , Complement System | |
W-54011 is a potent non-peptide C5a receptor antagonist. W-54011 inhibits the binding of 125I-labeled C5a to human neutrophils (Ki: 2.2 nM). W-54011 inhibits C5a-induced intracellular Ca2+ mobilization, chemotaxis, and g... | |||
T8320 | J14 | J-14 | Reactive Oxygen Species |
J-14 is an inhibitor of reversible sulfiredoxin(IC50 : 8.1 μM). J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin, leading to cytotoxicity and cancer cell death | |||
T13019 | Succinyl phosphonate trisodium salt | Dehydrogenase , Reactive Oxygen Species , Endogenous Metabolite | |
Succinyl phosphonate trisodium salt is an inhibitor of α-ketoglutarate dehydrogenase (KGDHC) | |||
T8377 | Mesotrione | Reactive Oxygen Species | |
Mesotrione is a selective triketone herbicide | |||
T6699 | Tempol | TMPN,Tanol,4-Hydroxy-TEMPO | Reactive Oxygen Species , ROS , Autophagy |
Tempol (Tanol) is a superoxide scavenger. It has anti-inflammatory, neuroprotective and analgesic effects. | |||
T6482 | Efaproxiral Sodium | RSR13 sodium | Reactive Oxygen Species |
Efaproxiral Sodium (RSR13 sodium), a synthetic allosteric modifier of hemoglobin, is utilized for brain metastases originating from breast cancer. | |||
T4287 | Succinobucol | Probucol monosuccinate,AGI-1067 | Antioxidant , Reactive Oxygen Species |
Succinobucol (Probucol monosuccinate) is a novel phenolic antioxidant small molecule with anti-oxidant and anti-inflammatory properties. It designed to treat atherosclerosis of the blood vessels of the heart or coronary ... | |||
T0163 | Nisoldipine | BAY-k 5552 | Calcium Channel , Reactive Oxygen Species |
Nisoldipine (BAY-k 5552) is a dihydropyridine calcium channel antagonist that acts as a potent arterial vasodilator and antihypertensive agent. | |||
T38423 | CL097 | CL097 | Reactive Oxygen Species , TLR |
CL097 is an effective agonist of TLR7 and TLR8. CL097 induces pro-inflammatory cytokines in macrophages and NADPH oxidase priming, thereby increasing the fMLF-stimulated ROS production. | |||
T7191 | Diphenyleneiodonium chloride | DPI | NOS , Reactive Oxygen Species , NADPH , TRP/TRPV Channel |
Diphenyleneiodonium chloride (DPI)(DPI) is an irreversible inhibitor of iNOS and eNOS (IC50 values of 50 nM and 0.3 μM, respectively),and displays broad-spectrum bactericidal activity. | |||
T11580 | Heme Oxygenase-1-IN-1 | HO-1-IN-1 | Reactive Oxygen Species |
Heme Oxygenase-1-IN-1 (HO-1-IN-1) is a heme oxygenase 1 (HO-1) inhibitor (IC50: 250 nM). | |||
T40612 | Manganese(salen) chloride | EUK-8 | Others |
Manganese(salen) chloride (EUK-8) (EUK-8) is a superoxide dismutase and catalase mimetic. Manganese(salen) chloride (EUK-8) is an antioxidant with oxyradical scavenging properties. Manganese(salen) chloride ameliorates a... | |||
T15213 | Emeramide | BDTH2 | Reactive Oxygen Species |
Emeramide (BDTH2) is a thiol-redox antioxidant. It is also a heavy metal chelator. | |||
T4172 | Methoxy-PMS | 1-Methoxyphenazine methosulfate,1-Methoxy PMS | Reactive Oxygen Species |
Methoxy-PMS (1-Methoxyphenazine methosulfate) is stable electron-transport mediator between NAD(P)H and tetrazolium dyes, can induce active oxygen formation. | |||
T2587 | Ecabet Sodium | TA-2711E,TA-2711 | Reactive Oxygen Species , Antibacterial |
Ecabet Sodium (TA-2711) is a potential new agent in the management of distal colitis. | |||
T7717 | Sodium 2-oxopropanoate | Sodium pyruvate | Reactive Oxygen Species , Endogenous Metabolite |
Sodium 2-oxopropanoate (Sodium pyruvate) is a antioxidant potentially used to treatment of chronic obstructive pulmonary disease. | |||
T9211 | Mito-LND | Mito-Loidamine | OXPHOS , Reactive Oxygen Species , Mitochondrial Metabolism , Autophagy |
Mito-LND (Mito-Loidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation. | |||
T12059L | Mitoquinone mesylate | MitoQ mesylate,MitoQ10 mesylate | Reactive Oxygen Species |
T21011 | Buspirone | Buspirone free base,Ansial | 5-HT Receptor |
Buspirone (Buspirone free base) is an azaspiro compound which has a role as an anxiolytic drug, a sedative, a serotonergic agonist and an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
TQ0212 | Glucoraphanin | Antioxidant , Reactive Oxygen Species | |
Glucoraphanin, the precursor of the widely extolled chemopreventive agent sulforaphane found in broccoli, has antioxidant activity. | |||
T3S1692 | Octahydrocurcumin | Anti-infection , NF-κB , Reactive Oxygen Species , ROS | |
Octahydrocurcumin has antioxidant and and anti-inflammatory activities, it can inhibit the lipopolysaccharide (LPS)-induced inflammatory response via the mechanism of inhibiting NF-kB translocation to the nucleus. Octahy... | |||
T1716 | Echinacoside | Reactive Oxygen Species , Wnt/beta-catenin | |
Echinacoside is a natural polyphenolic compound with various kinds of pharmacological activities, such as anti-inflammatory, antioxidative, hepatoprotective, neuroprotective, nitric oxide radical-scavenging and vasodilat... | |||
TN1403 | Arjunolic acid | IL Receptor , TNF , Reactive Oxygen Species , JNK , AChE | |
Arjunolic acid has antioxidant, anti-inflammatory, antinociceptive and anticholinesterasic (AChE and BuChE) activities, it may as promising targets for the development of innovative multi-functional medicines for Alzheim... | |||
TQ0288 | Hexahydrocurcumin | Reactive Oxygen Species , ROS , COX | |
Hexahydrocurcumin is a selective, orally active COX-2 inhibitor and inactive against COX-1. | |||
T16747 | Riboflavin Tetrabutyrate | Reactive Oxygen Species | |
T3399 | Psoralidin | Others , Estrogen/progestogen Receptor , Reactive Oxygen Species , Lipoxygenase , Gamma-secretase , Akt , COX , Antibacterial | |
Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally. Psoralidin possesses anticancer and chemopreventive properties. | |||
T6S2038 | Ziyuglycoside II | Apoptosis , Antioxidant , Reactive Oxygen Species | |
1. Ziyuglycoside II has anti-inflammation and antioxidation properties. 2. Ziyuglycoside II has antibiosis, and homeostasis properties. 3. Ziyuglycoside II has anticancer, and antitumor properties against gastric cancer ... | |||
T2866 | Echinocystic acid | Apoptosis , Antioxidant , Reactive Oxygen Species | |
Echinocystic acid (EA), a natural triterpone enriched in various herbs, shows a range of pharmacological activities including anti-inflammatory and antioxidant effects. | |||
T2818 | Methyl Vanillate | Reactive Oxygen Species , Wnt/beta-catenin , Endogenous Metabolite | |
Methyl vanillate is Hovenia Dulcis Thunb extract and its ingredient methyl vanillate activate Wnt/β-catenin pathway and increase bone mass in growing or ovariectomized mice. Methyl vanillate is considered to be a slightl... | |||
TN2167 | Rutaevin | Reactive Oxygen Species , NO Synthase | |
Rutaevin shows the inhibitory activity on nitric oxide (NO) production in lipopolysaccharide-activated RAW264.7 macrophages, it may be as a valuable anti-inflammatory agent. | |||
T9057 | Norbergenin | IL Receptor , TNF , Reactive Oxygen Species | |
Norbergenin is a chemical compound. It is the O-demethylated derivative of bergenin. It can be isolated from rhizomes of Bergenia stracheyi. | |||
T8033 | Sodium Thiocyanate | Others , Reactive Oxygen Species , Interleukin | |
Sodium Thiocyanate, one of the main sources of the thiocyanate anion, is used as a precursor for the synthesis of pharmaceuticals and other specialty chemicals. | |||
TN1058 | Pelargonidin chloride | NOS , Reactive Oxygen Species , Nrf2 , NO Synthase | |
Pelargonidin chloride shows protective effect against CTN-induced oxidative stress in HepG2 cells and up-regulated the activity of detoxification enzyme levels through Keap1/Nrf2 signaling pathway. | |||
T10668 | Camalexin | Reactive Oxygen Species , ROS , Antibacterial , Antifungal | |
Camalexin is a phytoalexin isolated from Camelina sativa. It has antifungal, antibacterial, antiproliferative, and anticancer activities. Camalexin can induce ROS production. | |||
TN1674 | Garcinone D | Reactive Oxygen Species , Nrf2 , STAT | |
Garcinone D shows significant cytotoxicity against the CEM-SS cell line, with IC(50) value of 3.2 microg/ml; it exhibits dose-dependent enzyme-based microsomal aromatase inhibitory activity. Garcinone D inhibits p65 acti... | |||
TN6735 | Bigelovin | Apoptosis , Reactive Oxygen Species , Retinoid Receptor , Autophagy , RAR/RXR | |
Bigelovin is a selective retinoid X receptor α agonist. Bigelovin suppresses tumor growth through inducing apoptosis and autophagy via the inhibition of mTOR pathway regulated by ROS generation.It is also known as a pote... | |||
T36735 | 3,5-Di-tert-butylphenol | Reactive Oxygen Species , Antifungal | |
3,5-Di-tert-butylphenol induces accumulation of reactive oxygen species. 3,5-Di-tert-butylphenol exhibits anti-biofilm and antifungal activities. | |||
T8347 | Rifamycin S | Reactive Oxygen Species , ROS , Antibacterial , Antibiotic | |
Rifamycin S is a potent DNA-dependent RNA polymerase inhibitor,is a quinone and an antibiotic agnet against Gram-positive bacteria | |||
T4902 | Isotrifoliin | Isoquercetin,Isoquercitroside | Reactive Oxygen Species |
T3332 | Isosteviol | (-)-Isosteviol | IL Receptor , Potassium Channel , TNF , NF-κB , Reactive Oxygen Species , COX , Topoisomerase |
Isosteviol ((-)-Isosteviol), a common natural sweetener, belongs to tetracyclic diterpene glycosides. The pharmacology researches have suggested that stevioside and its hydrolysis products, steviol, isosteviol and stevio... | |||
TN5634 | Aureusidin | Auresudidin,Auresidin | Antioxidant , Reactive Oxygen Species , Lipoxygenase |
Aureusidin (Auresidin) shows antioxidant and lipoxygenase inhibitory activity with anti-inflammatory effects. | |||
T0465 | Ellagic acid | Gallogen,Elagostasine | Hedgehog/Smoothened , Casein Kinase , Reactive Oxygen Species , Topoisomerase , Endogenous Metabolite , PKA , Syk , PKC , Carbonic Anhydrase |
Ellagic acid (Gallogen) is a fused four ring compound isolated from the kino of Eucalyptus maculata Hook and E. Hemipholia F. Muell. Activates Factor XII of the blood clotting system which also causes kinin release; used... | |||
T2174 | Quercetin | Sophoretin | Apoptosis , Mitophagy , Reactive Oxygen Species , PI3K , Autophagy |
Quercetin (Sophoretin) is a natural flavonoid and is an agonist of SIRT1. Quercetin is also a PI3K inhibitor, inhibiting PI3Kγ, PI3Kδ, and PI3Kβ (IC50=2.4/3.0/5.4 μM). Quercetin can induce apoptosis and autophagy. | |||
T2864 | Lycopene | ψ,ψ-Carotene | Reactive Oxygen Species , ROS |
Lycopene (ψ,ψ-Carotene) is a linear, unsaturated hydrocarbon carotenoid, the major red pigment in fruits such as tomatoes, pink grapefruit, apricots, red oranges, watermelon, rosehips, and guava. As a class, carotenoids ... | |||
T3861 | Isobavachalcone | Corylifolinin,Isobacachalcone | Apoptosis , Others , Reactive Oxygen Species , Akt , Autophagy |
Isobavachalcone (Corylifolinin) is a chalcone constituent of Angelica keiskei, has potent anti-inflammatory activity, possible can ameliorate neuronal injury in brain diseases associated with inflammation. | |||
T2834 | Nobiletin | Hexamethoxyflavone | Apoptosis , MMP , Reactive Oxygen Species , ROR , Autophagy |
Nobiletin (Hexamethoxyflavone) is a natural polymethoxylated flavone isolated from citrus peels with anti-inflammatory and anti-tumor activities. Nobiletin is practically insoluble (in water) and an extremely weak acidic... | |||
T6947 | Piperlongumine | PPLGM,Piplartine | Apoptosis , ERK , Ferroptosis , Reactive Oxygen Species , ROS , Antibacterial , Autophagy |
Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L. It selectively kills cancer cells and strengthens the level of reactive oxygen species (ROS). | |||
T41358 | 2-Hydroxybenzylamine | Others | |
2-Hydroxybenzylamine, a potent small molecule scavenger of IsoLGs, sequesters the reactive species as inert adducts. 2-Hydroxybenzylamine may be used to decrease early recurrence of atrial fibrillation and other atrial a... | |||
T6S1653 | Albiflorin | Alibiflorin | Reactive Oxygen Species |
1. Albiflorin (Alibiflorin) has anticonvulsant effect for pain relief. 2. Albiflorin and paeoniflorin has neuroprotective action against Glu toxicity. 3. Albiflorin and paeoniflorin significantly ameliorated Glu-induced ... | |||
T4518 | Licochalcone D | ERK , NF-κB | |
Licochalcone D may be a potential drug for human melanoma treatment by inhibiting proliferation, inducing apoptosis via the mitochondrial pathway and blocking cell migration and invasion. Licochalcone D has cardioprotect... | |||
T3429 | Protopine | Macleyine,Hypercorine,Corydinine,Biflorine,Fumarine | Reactive Oxygen Species , Platelet aggregation , Histamine Receptor |
Protopine (Fumarine) is a benzylisoquinoline alkaloid. It has been found to inhibit histamine H1 receptors and platelet aggregation, and acts as an analgesic. | |||
T3240 | Citronellol | dihydrogeraniol,(±)-β-Citronellol | Reactive Oxygen Species |
Citronellol ((±)-β-Citronellol) is used in insect repellents and perfumes and as a mite attractant. | |||
T8072 | S-Methyl-L-cysteine | S-Methylcysteine | Antioxidant , Reactive Oxygen Species |
S-Methyl-L-cysteine (S-Methylcysteine) is a natural product that acts as a substrate in the catalytic antioxidant system mediated by methionine sulfoxide reductase A (MSRA), with neuroprotective, antioxidative, and anti-... | |||
T0480 | Doxofylline | Doxophylline | PDE , Adenosine Receptor |
Doxofylline (Doxophylline) is a methylxanthine derivative with the presence of a dioxolane group in position 7. As a drug used in the treatment of asthma, doxofylline has shown similar efficacy to theophylline but with s... | |||
T5852 | Canthaxanthin | all-trans-Canthaxanthin,E 161g | Reactive Oxygen Species |
Canthaxanthin (E 161g) is a red-orange carotenoid that belongs to the xanthophyll group. This naturally occurring pigment is present in bacteria, algae and some fungi. | |||
T7781 | Reynoutrin | Reinutrin,Quercetin-3-D-xyloside | Reactive Oxygen Species |
Reynoutrin (Reinutrin) with antioxidant and radical-scavenging activity. | |||
T3744 | Veratric acid | Veratrumenoic acid,3,4-Dimethoxybenzoic acid | Reactive Oxygen Species , COX |
Veratric acid (3,4-Dimethoxybenzoic acid) is a simple benzoic acid derived from plants and fruits with anti-oxidant, anti-inflammation and blood pressure-lowering effects. | |||
T2796 | Coenzyme Q10 | Ubiquinone-10,CoQ10 | Ferroptosis , Reactive Oxygen Species , Endogenous Metabolite |
Coenzyme Q10 (CoQ10) (ubiquinone) is a naturally occurring compound, acting as the electron carrier in the mitochondrial respiratory chain. | |||
T2992 | Pinocembrin | 5,7-Dihydroxyflavanone,Dihydrochrysin,Galangin flavanone | NF-κB , Reactive Oxygen Species , Antibacterial , Autophagy |
Pinocembrin (5,7-Dihydroxyflavanone) is a flavanone, a type of flavonoid. It is an antioxidant found in damiana, honey, fingerroot, and propolis. | |||
T5A2461 | Bufotalin | Bufotaline | Apoptosis , Others , Reactive Oxygen Species |
1. Bufotalin (Bufotaline)e is a kind of poisonous secretions of toads. | |||
TN1141 | Isodeoxyelephantopin | NF-κB , Reactive Oxygen Species , Autophagy | |
Isodeoxyelephantopin exerts antitumor effects on several cancer cells by inducing apoptosis , cell cycle arrest , and inhibiting proliferation. It enhances apoptosis and inhibit invasion and osteoclastogenesis by inhibit... | |||
T3753 | Sinapinic Acid | Sinapic acid,Synapoic acid | Apoptosis , RAAS , Reactive Oxygen Species , HDAC |
Sinapinic Acid (Synapoic acid) protects the rat liver from CCl4-induced inflammation, most likely by acting as a free radical scavenger and modulator of NF-κB p65 activation and proinflammatory cytokine expression. Sinap... | |||
T3S1089 | Phillygenin | Epipinoresinol methyl ether,(+)-Phillygenin,Phillygenol,Sylvatesmin,Forsythigenol | Reactive Oxygen Species |
1. Phillyrin, (+)-Phillygenin (Sylvatesmin), and (-)-phillygenin exert the strongest inhibitory activities on NO production with IC(5) values. | |||
T8693 | Diallyl Trisulfide | Apoptosis , Reactive Oxygen Species , Antifungal | |
Diallyl Trisulfide is an organic polysulfide compound found in garlic that acts as an H2S donor. | |||
T0928 | L-Ascorbic acid | Vitamin C,Ascorbic acid,L(+)-Ascorbic acid,L-Ascorbate | Apoptosis , Calcium Channel , Reactive Oxygen Species , Endogenous Metabolite |
L-Ascorbic acid (Vitamin C) is a natural product that is a potent reducing agent and antioxidant. L-Ascorbic acid functions in fighting bacterial infections, in detoxifying reactions, and in the formation of collagen. L-... | |||
T3785 | 11-oxo-mogroside V | 11-oxo Mogroside V | Reactive Oxygen Species |
11-oxo-mogroside V (11-oxo Mogroside V) is a sweet tasting cucurbitane glycoside derivative of mogroside V. It has antioxidant effects against both O2- and OH- and prevents OH-induced DNA damage. | |||
T1717 | Alpha-Mangostin | α-Mangostin,Mangostin | Apoptosis , Virus Protease , Dehydrogenase , Reactive Oxygen Species , Antibacterial , Antifungal |
alpha-Mangostin (Mangostin) is a natural xanthonoid, a type of organic compound isolated from various parts of the mangosteen tree. | |||
T4S0797 | Berberine | Berberin,Umbellatine | Reactive Oxygen Species , Topoisomerase , Endogenous Metabolite , Antibacterial , Antibiotic , Autophagy |
1. Berberine (Umbellatine) is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism. 2. Berberine may as a broad-spectrum anti-microbial medicine, a complementary therapeutic agent for HIV/AIDS. 3.... | |||
T6S1367 | Procyanidin B2 | Proanthocyanidin B2 | Reactive Oxygen Species , NOD |
Procyanidin B2 (Proanthocyanidin B2) has vascular protective, anti-diabetic nephropathy, anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inflammasome activation via suppression ... | |||
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カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-03363 | C-Reactive Protein Protein, Human, Recombinant | Human | HEK293 Cells |
C-Reactive Protein Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 23 kDa and the accession number is P02741-1. | |||
TMPY-02047 | C-Reactive Protein Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
C-Reactive Protein Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.6 kDa and the accession number is H6X2V1. | |||
TMPK-00114 | C-Reactive Protein /CRP Protein, Human, Recombinant (His) | Human | HEK293 Cells |
C-reactive protein (CRP) is a polypeptide molecule belonging to the family of pentraxins. CRP is synthesized primarily by the liver in response to certain pro-inflammatory cytokines. It plays an important role in innate ... | |||
TMPY-05336 | C-Reactive Protein Protein, Human, Recombinant, Biotinylated | Human | HEK293 Cells |
C-Reactive Protein Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 23 kDa and the accession number is P02741-1. | |||
TMPY-01581 | C-Reactive Protein Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
C-Reactive Protein Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.4 kDa and the accession number is P14847. | |||
TMPY-06937 | C-Reactive Protein Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
C-Reactive Protein Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 26.3 kDa and the accession number is P02741-1. | |||
TMPK-01333 | C-Reactive Protein /CRP Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
C-reactive protein (CRP) is a polypeptide molecule belonging to the family of pentraxins. CRP is synthesized primarily by the liver in response to certain pro-inflammatory cytokines. It plays an important role in innate ... | |||
TMPJ-00495 | ISG15 Protein, Human, Recombinant (His) | Human | E. coli |
Ubiquitin-Like Protein ISG15 (ISG15) is a ubiquitin-like protein that becomes conjugated to many cellular proteins upon activation by interferon-alpha and -beta. Several functions have been ascribed to the encoded protei... | |||
TMPJ-00506 | PSG5 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Pregnancy-specific beta-1-glycoprotein 5, is a secreted protein which belongs to the immunoglobulin superfamily, CEA family. It contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobuli... | |||
TMPJ-00155 | Mucin-1/MUC1 Protein, Human, Recombinant (hFc&Avi), Biotinylated | Human | HEK293 Cells |
Mucin-1, is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also ... | |||
TMPK-01416 | HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi), Biotinylated | Human | HEK293 Cells |
HLA-B*15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B*15:01 we... | |||
TMPK-01412 | HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
HLA-B*15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B*15:01 we... | |||
TMPH-01318 | SOD3 Protein, Human, Recombinant | Human | E. coli |
Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen. SOD3 Protein, Human, Recombinant is expressed in E. coli expression ... | |||
TMPY-02044 | SOD2 Protein, Human, Recombinant | Human | E. coli |
Superoxide dismutases (SOD) are important anti-oxidant enzymes that guard against superoxide toxicity. In humans, as in all mammals and most chordates, three forms of superoxide dismutase (SOD) are present: SOD1 is locat... | |||
TMPY-02425 | Serpin B4, Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Overexpression of SERPINB4 in tumor cells inhibited recombinant GrM-induced as well as NK cell-mediated cell death and this inhibition depended on the reactive center loop of the serpin. | |||
TMPH-00448 | SVMP Protein, Crotalus adamanteus, Recombinant (His) | Crotalus adamanteus | E. coli |
Has no significant hemorrhagic activity, but inactivates serpins by limited proteolysis of their reactive-site loops. SVMP Protein, Crotalus adamanteus, Recombinant (His) is expressed in E. coli expression system with N-... | |||
TMPH-02198 | TXNRD2 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Involved in the control of reactive oxygen species levels and the regulation of mitochondrial redox homeostasis. Maintains thioredoxin in a reduced state. May play a role in redox-regulated cell signaling. | |||
TMPH-01317 | SOD3 Protein, Human, Recombinant (His) | Human | E. coli |
Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen. SOD3 Protein, Human, Recombinant (His) is expressed in E. coli expre... | |||
TMPH-02681 | GPX7 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
It protects esophageal epithelia from hydrogen peroxide-induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks. G... | |||
TMPH-01298 | EPHX1 Protein, Human, Recombinant (His) | Human | E. coli |
Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Plays a role in the metabolism of endogenous lip... | |||
TMPH-02106 | SH3PXD2A Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides... | |||
TMPH-02875 | ROMO1 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.; Induces production of reactive oxygen species (ROS) which are n... | |||
TMPK-00571 | OSMR Protein, Canine, Recombinant (His) | Canine | HEK293 Cells |
OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and prom... | |||
TMPH-02104 | Sestrin-3/SESN3 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway. May also regulate the insulin-receptor signaling pathway through activation of TORC2. This metabolic regulator may al... | |||
TMPH-00099 | NDK1 Protein, Arabidopsis thaliana, Recombinant (His & Myc) | Arabidopsis thaliana | P. pastoris (Yeast) |
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Plays a... | |||
TMPK-00493 | OSMR Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and prom... | |||
TMPH-01597 | KYAT1 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the thre... | |||
TMPY-02271 | TRXR1/TXNRD1 Protein, Human, Recombinant (aa 161-647, His) | Human | E. coli |
Thioredoxin reductase 1 (TXNRD1) which is a selenocysteine-containing protein is overexpressed in many malignancies. TXNRD1 plays a key role in regulating cell growth and transformation, and protects cells against oxidat... | |||
TMPH-00035 | Polyphenol oxidase 2 Protein, Agaricus bisporus, Recombinant (His) | Agaricus bisporus | Baculovirus Insect Cells |
Copper-containing oxidase that catalyzes both the o-hydroxylation of monophenols and the subsequent oxidation of the resulting o-diphenols into reactive o-quinones, which evolve spontaneously to produce intermediates, wh... | |||
TMPJ-00753 | Myoglobin Protein, Human, Recombinant (His) | Human | E. coli |
Myoglobin(MB) is a cytoplasmic protein expressed in myocytes of the heart and skeletal muscle that reversibly binds oxygen. It belongs to the globin family. Functions of myoglobin include oxygen storage and transport, as... | |||
TMPJ-00931 | Serpin A4 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Serpin Peptidase Inhibitor, Clade A (α-1 Antiproteinase, Antitrypsin), Member 4 (Serpin A4) is a member of the Serpin family. Serpin A4 exists as a monomer and some homodimers. Serpin A4 is expressed by the liver and sec... | |||
TMPJ-00848 | NCF1 Protein, Human, Recombinant (His) | Human | E. coli |
Neutrophil cytosol factor 1( NCF1) is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is characterized as a multicomponent enzyme which is activated to produce superoxide anion. NCF2, NCF1, and a mem... | |||
TMPH-02585 | ACOD1 Protein, Mouse, Recombinant (His & Myc) | Mouse | Baculovirus Insect Cells |
Cis-aconitate decarboxylase that catalyzes production of itaconate and is involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory inna... | |||
TMPJ-00933 | PRDX5 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Peroxisomes are essential organelles that participate in multiple important metabolic processes, including the β-oxidation of fatty acids, plasmalogen synthesis, and the metabolism of reactive oxygen species (ROS). Perox... | |||
TMPY-00055 | LCAT Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Lecithin: cholesterol acyltransferase (LCAT) is the sole enzyme that esterifies cholesterol in plasma, thus determining the maturation of high-density lipoproteins. Because it maintains an unesterified cholesterol gradie... | |||
TMPJ-01274 | ERO1L Protein, Human, Recombinant (His) | Human | HEK293 Cells |
ERO1-Like Protein α (ERO1L) is an enzyme that belongs to the EROs family. ERO1L is expressed at high level in esophagus and upper digestive tract. ERO1L is an essential oxidoreductase that oxidizes proteins in the endopl... | |||
TMPY-05001 | MPZL3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
MPZL3 (Myelin Protein Zero Like 3) is a Protein Coding gene. The encoded protein belongs to the myelin P0 protein family. MPZL3 is broadly expressed in skin, esophagus, and other tissues. MPZL3 was essential for normal d... | |||
TMPH-01214 | DNASE1L3 Protein, Human, Recombinant | Human | E. coli |
Has DNA hydrolytic activity. Is capable of both single- and double-stranded DNA cleavage, producing DNA fragments with 3'-OH ends. Can cleave chromatin to nucleosomal units and cleaves nucleosomal and liposome-coated DNA... | |||
TMPH-01212 | DNASE1L3 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Has DNA hydrolytic activity. Is capable of both single- and double-stranded DNA cleavage, producing DNA fragments with 3'-OH ends. Can cleave chromatin to nucleosomal units and cleaves nucleosomal and liposome-coated DNA... | |||
TMPH-01213 | DNASE1L3 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Has DNA hydrolytic activity. Is capable of both single- and double-stranded DNA cleavage, producing DNA fragments with 3'-OH ends. Can cleave chromatin to nucleosomal units and cleaves nucleosomal and liposome-coated DNA... | |||
TMPJ-00833 | MPO Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Myeloperoxidase (MPO) is a hemecontaining enzyme belonging to the XPO subfamily of peroxidases. It is an abundant neutrophil and monocyte glycoprotein that catalyzes the hydrogen peroxidedependent conversion of chloride,... | |||
TMPY-01635 | PCSK1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Neuroendocrine convertase 1, also known as Prohormone convertase 1, Proprotein convertase 1, PCSK1 and NEC1, is an enzyme which belongs to the peptidase S8 family and Furin subfamily. PCSK1 is an enzyme that performs the... | |||
TMPY-02043 | PARK7/DJ-1 Protein, Human, Recombinant (His) | Human | E. coli |
Parkinson's disease locus DJ-1 (PARK7) is a differentially expressed transcript. DJ-1 plays a physiologic role in protection of erythroid cells from oxidant damage, a function unmasked in the context of oxidative stress.... | |||
TMPY-01632 | Serpin B4 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus Insect Cells |
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesi... | |||
TMPY-01816 | Pentraxin 3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Pentraxin-related protein PTX3, also known as Tumor necrosis factor alpha-induced protein 5, Tumor necrosis factor-inducible gene 14 protein, TSG-14, PTX3 and TNFAIP5, is a secreted protein that contains one pentaxin dom... | |||
TMPY-04813 | ACAT2 Protein, Rat, Recombinant (His) | Rat | E. coli |
Acyl-coenzyme A: cholesterol acyltransferase (ACAT) is an intracellular enzyme that produces cholesteryl esters in various tissues. In mammals, two ACAT genes (ACAT1 and ACAT2) have been identified. Together, these two e... | |||
TMPH-01263 | PRKN Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Substrates include SYT11 and VDAC1. Other substrates are BCL2, CCNE1, GPR37, ... | |||
TMPH-02631 | PRKN Protein, Mouse, Recombinant (GST) | Mouse | E. coli |
Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Substrates include SYT11 and VDAC1. Other substrates are BCL2, CCNE1, GPR37, ... |
カタログ番号 | 製品名 | ||
---|---|---|---|
L2910 | Antioxidant Compound Library | 1314 compounds | |
Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species (ROS) and a biological system's ability to readily detoxify the reactive intermediates or repair the resulting damage. ... | |||
L7850 | High Solubility 3D Diversity Fragment Library | 1079 compounds | |
The library of highly soluble 3D structural diversity fragments contains 1079 compounds. | |||
L7820 | High Solubility Micro Fragment Library | 1081 compounds | |
The compound library of highly soluble micro-fragments consists of 1081 low-molecular-weight fragments. | |||
L5510 | Drug-induced Liver Injury (DILI) Compound Library | 1001 compounds | |
A unique collection of 1001 hepatotoxicity causing compounds, a powerful tool for drug toxicity study, can be used for HTS and HCS screening; | |||
L5300 | Mitochondria-Targeted Compound Library | 812 compounds | |
A unique collection of 812 promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine; | |||
L9410 | Covalent Inhibitor Library | 1920 compounds | |
A unique collection of 1920 covalent Inhibitors and other molecules with common warheads like chloroacetyl,2-Chloropropionyl,Acryloyl,sulfonyl fluoride, alkyne,acrylamide, ketocarbonyl,disulfide bond, etc. |