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Search Results for " Hypoxia "

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カタログ番号	製品名	別名	ターゲット
T32124	HyP-1	HyP 1,HyP1,Hypoxia Probe 1
	HyP-1 is a probe for photoacoustic imaging of hypoxia.
T50099	HIF-2α-IN-4		Others , HIF/HIF Prolyl-Hydroxylase
	HIF-2a translation inhibitor is a compound used as a molecular building block.		Others , HIF/HIF Prolyl-Hydroxylase
T3169	KC7F2		HIF/HIF Prolyl-Hydroxylase , HIF
	KC7F2 is a potent HIF-1 pathway inhibitor with potential anti-cancer activity.		HIF/HIF Prolyl-Hydroxylase , HIF
T22022	Adaptaquin		HIF
	Adaptaquin is an inhibitor of the hypoxia-inducing factor prolyl hydroxylase (HIF-PH) [1] [2].		HIF
T0244	Tilorone dihydrochloride		Influenza Virus , HIF/HIF Prolyl-Hydroxylase , IFNAR
	Tilorone dihydrochloride is an orally active interferon inducer, and has antineoplastic and anti-inflammatory actions.		Influenza Virus , HIF/HIF Prolyl-Hydroxylase , IFNAR
T7880	IOX4		HIF/HIF Prolyl-Hydroxylase
	IOX4 is a potent PHD2 inhibitor (IC50 = 1.6 nM)		HIF/HIF Prolyl-Hydroxylase
T7848	PT-2385		HIF/HIF Prolyl-Hydroxylase , HIF
	PT-2385 is a selective HIF-2α inhibitor (Kd<50 nM).		HIF/HIF Prolyl-Hydroxylase , HIF
T5392	TP0463518		HIF/HIF Prolyl-Hydroxylase
	TP-0463518 is a highly potent HIF prolyl hydroxylase (PHD) inhibitor (IC50s: 13 nM and 18 nM for human and rat PHD2, respectively).		HIF/HIF Prolyl-Hydroxylase
T13398	ZINC13466751		HIF
	ZINC13466751 is a potent HIF-1α/von Hippel-Lindau interaction inhibitor(IC50 of 2.0 µM).		HIF
T2652	Molidustat	BAY 85-3934	HIF/HIF Prolyl-Hydroxylase
	Molidustat (BAY 85-3934)(BAY-85-3934), an inhibitor of hypoxia-inducible factor (HIF) prolyl hydroxylase (PH), stimulates erythropoietin (EPO) production and the formation of red blood cells.		HIF/HIF Prolyl-Hydroxylase
T13050	SYP-5		HIF/HIF Prolyl-Hydroxylase , HIF
	SYP-5 is a novel inhibitor of HIF-1, suppresses tumor cells invasion and angiogenesis.		HIF/HIF Prolyl-Hydroxylase , HIF
T12675L	PT2399		HIF/HIF Prolyl-Hydroxylase , HIF
	PT2399 shows effective antitumor activity in vivo. PT2399 is an effective and selective HIF-2α antagonist, which directly binds to the HIF-2α PAS B domain (IC50: 6 nM).		HIF/HIF Prolyl-Hydroxylase , HIF
T5537	IDF-11774		HIF/HIF Prolyl-Hydroxylase , HIF
	IDF-11774 is a HIF-1 inhibitor.It reduces hif-1α HRE luciferase activity (IC50 = 3.65 μM).		HIF/HIF Prolyl-Hydroxylase , HIF
T4106	MK-8617	MK8617	HIF/HIF Prolyl-Hydroxylase
	MK-8617 is an orally available HIF PHD1 3 pan-inhibitor, inhibiting PHD1/2/3 (IC50: 1.0/1.0/14 nM).		HIF/HIF Prolyl-Hydroxylase
T2488	BAY 87-2243		Ferroptosis , HIF/HIF Prolyl-Hydroxylase , HIF
	BAY 87-2243 is a potent and selective inhibitor of hypoxia-inducible factor-1 (HIF-1).		Ferroptosis , HIF/HIF Prolyl-Hydroxylase , HIF
T15219	Enarodustat	JTZ-951	Others , HIF/HIF Prolyl-Hydroxylase
	Enarodustat (JTZ-951) is an orally active factor inhibitor of prolyl hydroxylase (EC50: 0.22 μM) and has the potential for renal anemia treatment.		Others , HIF/HIF Prolyl-Hydroxylase
T3197	Daprodustat	GSK1278863	HIF/HIF Prolyl-Hydroxylase , HIF
	Daprodustat (GSK1278863) is a HIF-prolyl hydroxylase inhibitor.		HIF/HIF Prolyl-Hydroxylase , HIF
T21653	1,4-DPCA		HIF/HIF Prolyl-Hydroxylase
	1,4-DPCA is an inhibitor of prolyl-hydroxylase with an IC50 of 2.4 µM for collagen hydroxylation in human foreskin fibroblasts and 60 μM for factor inhibiting HIF (FIH).		HIF/HIF Prolyl-Hydroxylase
T64336	Izilendustat		HIF/HIF Prolyl-Hydroxylase
	Tert-butyl 4-[[1-[(4-chlorophenyl)methyl]-3-hydroxy-2-oxopyridin-4-yl]methyl]piperazine-1-carboxylate inhibit of human recombinant EGLN-1 as substrate after 20 mins by mass spectrophotometric analysis.		HIF/HIF Prolyl-Hydroxylase
T15396	GN44028	N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,4-dihydroindeno[1,2-c]pyrazol-3-amine	HIF
	GN44028 (N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,4-dihydroindeno[1,2-c]pyrazol-3-amine) is a hypoxia-inducible factor inhibitor of (HIF)-1 (IC50: 14 nM). GN44028 inhibits hypoxia-induced HIF-1α transcriptional activity. H...		HIF
T7802	M1001		HIF/HIF Prolyl-Hydroxylase , HIF
	M1001 is a HIF-2α agonist.		HIF/HIF Prolyl-Hydroxylase , HIF
T11561	HIF-2α-IN-2		HIF/HIF Prolyl-Hydroxylase , HIF
	HIF-2α-IN-2 is a hypoxia-inducible factor (HIF-2α) inhibitor (IC50: 16 nM in scintillation proximity assay).		HIF/HIF Prolyl-Hydroxylase , HIF
T29797	AKB-6899	AKB6899	VEGFR , HIF/HIF Prolyl-Hydroxylase , HIF
	AKB-6899 is an inhibitor of prolyl hydroxylase domain 3 (PHD3) and increases the soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated macrophages. AKB-6899 leads to stabilization of HIF-2α which in...		VEGFR , HIF/HIF Prolyl-Hydroxylase , HIF
T21806	HNHA		HDAC
	HNHA is an inhibitor of HDAC.		HDAC
T1823	IOX2	IOX 2,JICL38	HIF/HIF Prolyl-Hydroxylase
	IOX2 (IOX 2) is a selective inhibitor of the Hypoxia Inducible Factor (HIF) Prolyl-Hydroxylases (PHD); active in cells with the IC50 value of 21 nM for PHD2/ELGN-1 and no inhibition at FIH (20uM).		HIF/HIF Prolyl-Hydroxylase
T9627	PHD-1-IN-1		HIF/HIF Prolyl-Hydroxylase
	PHD-1-IN-1 is a potent inhibitor of hypoxia-inducible factor prolylhydroxylase domain-1 (PHD-1) enzyme(IC50 = 0.034 μM).		HIF/HIF Prolyl-Hydroxylase
T6961	PX-478	PX-478 2HCl	HIF/HIF Prolyl-Hydroxylase , HIF , Autophagy
	PX-478 is a HIF-1α inhibitor with selectivity, oral activity, and blood-brain barrier permeability. PX-478 has antitumor activity and also protects pancreatic β-cell function in diabetes mellitus and is used in type 2 di...		HIF/HIF Prolyl-Hydroxylase , HIF , Autophagy
T3180	JNJ-42041935	HIF-PHD Inhibitor II	HIF/HIF Prolyl-Hydroxylase
	JNJ-42041935 (HIF-PHD Inhibitor II) is a potent (pKi = 7.3-7.9), 2-oxoglutarate competitive, reversible, and selective inhibitor of PHD enzymes.		HIF/HIF Prolyl-Hydroxylase
T1613	Hydralazine hydrochloride	Hydralazine HCl,Apresoline	MAO , HIF/HIF Prolyl-Hydroxylase
	Hydralazine hydrochloride (Apresoline) is the hydrochloride salt of hydralazine, a phthalazine derivative with antihypertensive and potential antineoplastic activities. Hydralazine alters intracellular calcium release an...		MAO , HIF/HIF Prolyl-Hydroxylase
T13289	EHP-101	VCE-004.8	Cannabinoid Receptor , HIF/HIF Prolyl-Hydroxylase , PPAR
	EHP-101 (VCE-004.8) is a specific dual agonist of PPARγ and CB2 receptor with potent anti-inflammatory activity. EHP-101 attenuates adipogenesis and prevents diet-induced obesity.		Cannabinoid Receptor , HIF/HIF Prolyl-Hydroxylase , PPAR
T16679	Belzutifan	PT2977,MK-6482	HIF
	Belzutifan (MK-6482) is a potential treatment for clear cell renal cell carcinoma (ccRCC). Belzutifan is an orally active and selective HIF-2α inhibitor (IC50: 9 nM). Belzutifan , as a second-generation HIF-2α inhibitor,...		HIF
T2515	Roxadustat	ASP1517,FG-4592	Ferroptosis , HIF/HIF Prolyl-Hydroxylase , HIF
	Roxadustat (FG-4592) is an orally bioavailable, hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI), with potential anti-anemic activity.		Ferroptosis , HIF/HIF Prolyl-Hydroxylase , HIF
T9890	HIF1-IN-3	Benzenepropanamide, N-[(8-hydroxy-7-quinolinyl)(4-methoxyphenyl)methyl]-	HIF
	HIF1-IN-3 (Benzenepropanamide, N-[(8-hydroxy-7-quinolinyl)(4-methoxyphenyl)methyl]-) is an effective inhibitor of HIF-1 (EC50 = 0.9 μM) and can be used in anticancer studies.		HIF
T1939	DMOG	Dimethyloxalylglycine,Dimethyloxallyl Glycine,Dimethyloxaloylglycine	HIF/HIF Prolyl-Hydroxylase , HIF , Autophagy
	DMOG (Dimethyloxalylglycine), an antagonist of the α-ketoglutarate cofactor, is an inhibitor for HIF prolyl hydroxylase.		HIF/HIF Prolyl-Hydroxylase , HIF , Autophagy
T2445	FG-2216	YM-311,FG2216,FG 2216	HIF/HIF Prolyl-Hydroxylase
	FG-2216 (YM-311) is a potent HIF-prolyl hydroxylase inhibitor for the PDH2 enzyme (IC50: 3.9 uM); orally bioavailable and induced reversible and significant Epo induction in vivo.		HIF/HIF Prolyl-Hydroxylase
T3289	Amifostine	Ethyol,WR2721,Gammaphos	Others , HIF/HIF Prolyl-Hydroxylase
	Amifostine (Ethyol) anhydrous is a cytoprotective agent, acts as a free radical scavenging activity.		Others , HIF/HIF Prolyl-Hydroxylase
T0153	Oltipraz	NSC 347901,RP 35972	HIF/HIF Prolyl-Hydroxylase , HIV Protease , Reverse Transcriptase , Nrf2 , HIF
	Oltipraz (RP 35972) is a synthetic dithiolethione with potential chemopreventive and anti-angiogenic properties. Oltipraz induces phase II detoxification enzymes, such as glutathione S transferase (GST) and NAD(P)H: quin...
T6381	Amifostine trihydrate	Ethyol trihydrate,WR2721,Amifostine	Others , HIF/HIF Prolyl-Hydroxylase
	Amifostine trihydrate (WR2721) is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.		Others , HIF/HIF Prolyl-Hydroxylase
T3494	LW6	HIF-1α inhibitor,CAY10585,LW8	Apoptosis , Dehydrogenase , HIF/HIF Prolyl-Hydroxylase , HIF
	LW6 (HIF-1α inhibitor) is a novel HIF-1 inhibitor.
T4651	Vadadustat	PG-1016548,AKB-6548	HIF/HIF Prolyl-Hydroxylase , HIF
	Vadadustat is a novel, titratable, oral hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor in development for the treatment of anemia.		HIF/HIF Prolyl-Hydroxylase , HIF
T1637	Deferoxamine Mesylate	desferrioxamine B,Desferrioxamine B mesylate,DFO,DFOM	Mitophagy , Beta Amyloid , Others , Ferroptosis , HIF/HIF Prolyl-Hydroxylase , Autophagy
	Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor. Deferoxamine Mesylate binds free iron into a stable complex and reduces iron accumulation. Deferoxamine Mesylate up-regulates HIF-1α levels and i...
T1101	Minocycline hydrochloride	Minocycline HCl	HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic
	Minocycline hydrochloride (Minocycline HCl) is a tetracycline antibiotic with excellent absorption and tissue penetration that is used for several bacterial infections as well as treatment of acne. Minocycline hydrochlor...		HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic
T6823	E3330		HIF/HIF Prolyl-Hydroxylase , DNA/RNA Synthesis
	E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.		HIF/HIF Prolyl-Hydroxylase , DNA/RNA Synthesis
T6804	Chetomin	Chaetomin,NSC289491,BRN0077366	Apoptosis , HSP , HIF
	Chetomin (BRN0077366) is an inhibitor of HIF-1 by weaken transcription of HIF-1, disrupting the binding of HIF-1α and HIF-2α to p300 at low nanomolar concentrations.		Apoptosis , HSP , HIF
T0143	Bisoprolol hemifumarate	(±)-Bisoprolol hemifumarate,Bisoprolol fumarate,Bisoprolol hemifumarate salt,EMD33512,(±)-Bisoprolol (hemifumarate)	Adrenergic Receptor
	Bisoprolol, a selective beta-1 adrenergic receptor antagonist, selectively and competitively binds to and blocks beta-1 adrenergic receptors in the heart, thereby with antihypertensive activity and devoid of intrinsic sy...		Adrenergic Receptor
T34705	SR4554	SR 4554	Others
	SR4554 is a fluorinated 2-nitroimidazole non-invasive tumor hypoxia probe for the detection of tumor hypoxia as detected by 19F magnetic resonance spectroscopy (MRS).		Others
T15202	EF-5	2-Nitroimidazole,EF5	Others
	EF-5 (2-Nitroimidazole) is a agent of hypoxia labeling. It is used to identify hypoxia in cells.		Others
T36711	FM19G11	FM19G11,HIF-1alpha/2alpha Inhibitor	HIF
	FM19G11 is an inhibitor of hypoxia inducible factor (HIF) α-subunit (IC50 = 80 nM in hypoxia induced luciferase assay).		HIF
T30549	BMY-21502	Bms-181168,Bms 181168,Bmy 21502,Bmy21502,Bms181168	Antioxidant
	BMY-21502 is a potential cognitive enhancer that shows anti-hypoxia effects in the KCN-hypoxia model, delays the decay of hippocampal synaptic enhancement in vitro, and can be used to study Alzheimer's disease.		Antioxidant
T16536	Pimonidazole hydrochloride
	Pimonidazole hydrochloride accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after the reduction of its nitro group. It can be used for qualitative and quantitative...

Compounds

HyP-1

T32124

Synonym: HyP 1,HyP1,Hypoxia Probe 1

Target: Others, HIF/HIF Prolyl-Hydroxylase

KC7F2

T3169

Synonym:

Target: HIF/HIF Prolyl-Hydroxylase, HIF

Tilorone dihydrochloride

T0244

Synonym:

Target: Influenza Virus, HIF/HIF Prolyl-Hydroxylase, IFNAR

IOX4

T7880

Synonym:

Target: HIF/HIF Prolyl-Hydroxylase

PT-2385

T7848

Synonym:

Target: HIF/HIF Prolyl-Hydroxylase, HIF

TP0463518

T5392

Synonym:

Target: HIF/HIF Prolyl-Hydroxylase

Target: HIF/HIF Prolyl-Hydroxylase

SYP-5

T13050

Synonym:

Target: HIF/HIF Prolyl-Hydroxylase, HIF

PT2399

T12675L

Synonym:

Target: HIF/HIF Prolyl-Hydroxylase, HIF

IDF-11774

T5537

Synonym:

Target: HIF/HIF Prolyl-Hydroxylase, HIF

MK-8617

T4106

Synonym: MK8617

Target: HIF/HIF Prolyl-Hydroxylase

BAY 87-2243

T2488

Synonym:

Target: Ferroptosis, HIF/HIF Prolyl-Hydroxylase, HIF

Enarodustat

T15219

Synonym: JTZ-951

Target: Others, HIF/HIF Prolyl-Hydroxylase

Daprodustat

T3197

Synonym: GSK1278863

Target: HIF/HIF Prolyl-Hydroxylase, HIF

1,4-DPCA

T21653

Synonym:

Target: HIF/HIF Prolyl-Hydroxylase

Izilendustat

T64336

Synonym:

Target: HIF/HIF Prolyl-Hydroxylase

GN44028

T15396

Synonym: N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,4-dihydroindeno[1,2-c]pyrazol-3-amine

Target: HIF/HIF Prolyl-Hydroxylase, HIF

HIF-2α-IN-2

T11561

Synonym:

Target: HIF/HIF Prolyl-Hydroxylase, HIF

AKB-6899

T29797

Synonym: AKB6899

Target: VEGFR, HIF/HIF Prolyl-Hydroxylase, HIF

Synonym: IOX 2,JICL38

Target: HIF/HIF Prolyl-Hydroxylase

PHD-1-IN-1

T9627

Synonym:

Target: HIF/HIF Prolyl-Hydroxylase

PX-478

T6961

Synonym: PX-478 2HCl

Target: HIF/HIF Prolyl-Hydroxylase, HIF, Autophagy

JNJ-42041935

T3180

Synonym: HIF-PHD Inhibitor II

Target: HIF/HIF Prolyl-Hydroxylase

Hydralazine hydrochloride

T1613

Synonym: Hydralazine HCl,Apresoline

Target: MAO, HIF/HIF Prolyl-Hydroxylase

EHP-101

T13289

Synonym: VCE-004.8

Target: Cannabinoid Receptor, HIF/HIF Prolyl-Hydroxylase, PPAR

Belzutifan

T16679

Synonym: PT2977,MK-6482

Target: HIF

Roxadustat

T2515

Synonym: ASP1517,FG-4592

Target: Ferroptosis, HIF/HIF Prolyl-Hydroxylase, HIF

HIF1-IN-3

T9890

Synonym: Benzenepropanamide, N-[(8-hydroxy-7-quinolinyl)(4-methoxyphenyl)methyl]-

Target: HIF

DMOG

T1939

Synonym: Dimethyloxalylglycine,Dimethyloxallyl Glycine,Dimethyloxaloylglycine

Target: HIF/HIF Prolyl-Hydroxylase, HIF, Autophagy

FG-2216

T2445

Synonym: YM-311,FG2216,FG 2216

Target: HIF/HIF Prolyl-Hydroxylase

Amifostine

T3289

Synonym: Ethyol,WR2721,Gammaphos

Target: Others, HIF/HIF Prolyl-Hydroxylase

Oltipraz

T0153

Synonym: NSC 347901,RP 35972

Target: HIF/HIF Prolyl-Hydroxylase, HIV Protease, Reverse Transcriptase, Nrf2, HIF

Amifostine trihydrate

T6381

Synonym: Ethyol trihydrate,WR2721,Amifostine

Target: Others, HIF/HIF Prolyl-Hydroxylase

LW6

T3494

Synonym: HIF-1α inhibitor,CAY10585,LW8

Target: Apoptosis, Dehydrogenase, HIF/HIF Prolyl-Hydroxylase, HIF

Vadadustat

T4651

Synonym: PG-1016548,AKB-6548

Target: HIF/HIF Prolyl-Hydroxylase, HIF

Deferoxamine Mesylate

T1637

Synonym: desferrioxamine B,Desferrioxamine B mesylate,DFO,DFOM

Target: Mitophagy, Beta Amyloid, Others, Ferroptosis, HIF/HIF Prolyl-Hydroxylase, Autophagy

Minocycline hydrochloride

T1101

Synonym: Minocycline HCl

Target: HIF/HIF Prolyl-Hydroxylase, Antibacterial, Antibiotic

E3330

T6823

Synonym:

Target: HIF/HIF Prolyl-Hydroxylase, DNA/RNA Synthesis

Chetomin

T6804

Synonym: Chaetomin,NSC289491,BRN0077366

Target: Apoptosis, HSP, HIF

Bisoprolol hemifumarate

T0143

Synonym: (±)-Bisoprolol hemifumarate,Bisoprolol fumarate,Bisoprolol hemifumarate salt,EMD33512,(±)-Bisoprolol (hemifumarate)

Target: Adrenergic Receptor

Synonym: 2-Nitroimidazole,EF5

Target: Others

FM19G11

T36711

Synonym: FM19G11,HIF-1alpha/2alpha Inhibitor

Target: HIF

BMY-21502

T30549

Synonym: Bms-181168,Bms 181168,Bmy 21502,Bmy21502,Bms181168

Target: Antioxidant

Pimonidazole hydrochloride

T16536

Synonym:

Target:

カタログ番号	製品名	別名	ターゲット
T6S0071	Fraxinellone		HIF/HIF Prolyl-Hydroxylase , STAT , PD-1/PD-L1
	1. Fraxinellone significantly reduced weight loss and diarrhea in mice and alleviated the macroscopic and microscopic signs of the disease. 2. Fraxinellone exhibited a variety of insecticidal activities including feeding...		HIF/HIF Prolyl-Hydroxylase , STAT , PD-1/PD-L1
T5S2347	Deoxyshikonin	Arnebin 7	Others , HIF/HIF Prolyl-Hydroxylase , Antibacterial
	1. Deoxyshikonin (Arnebin 7) may be a new drug candidate for wound healing and treatment of lymphatic diseases. 2. Deoxyshikonin enhances the ability of human dermal lymphatic microvascular endothelial cells (HMVEC-dLy) ...		Others , HIF/HIF Prolyl-Hydroxylase , Antibacterial
TL0001	Dencichine	L-Dencichin,ODAP,Dencichin	Others , HIF/HIF Prolyl-Hydroxylase
	Dencichine (ODAP) is a neurotoxic agent. Dencichine is a haemostatic agent, the hemostatic effect relates to modulation of the coagulation system, platelet aggregation and fibrinolytic system. It has renoprotective effec...		Others , HIF/HIF Prolyl-Hydroxylase
T5773	Moslosooflavone	5-hydroxy-7,8-dimethoxyflavone	NF-κB , Reactive Oxygen Species
	Moslosooflavone (5-hydroxy-7,8-dimethoxyflavone) has anti-hypoxia activity, it can significantly prolong the survival time of hypoxic mice. 5-hydroxy-7,8-dimethoxyflavone significantly inhibits the transcriptional activi...		NF-κB , Reactive Oxygen Species
T2763	Panaxadiol	20(R)-Panaxadiol	Others , HIF/HIF Prolyl-Hydroxylase
	Panaxadiol (20(R)-Panaxadiol) is a novel antitumor agent extracted from the Chinese medical herb Panax ginseng.		Others , HIF/HIF Prolyl-Hydroxylase
T0429	Glucosamine	Chitosamine,D-Glucosamine	MMP , Others , TNF , NF-κB , Reactive Oxygen Species , HIF/HIF Prolyl-Hydroxylase , Endogenous Metabolite , CFTR , Autophagy
	Glucosamine (Chitosamine) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. Supplemental glucosamine may help to rebuild cartilage and treat arthritis.
T6S1315	Oroxylin A	6-Methoxybaicalein,Baicalein 6-methyl ether	Virus Protease , HIF/HIF Prolyl-Hydroxylase , Autophagy
	1. Oroxylin A (Baicalein 6-methyl ether) has various anti-tumor effects including apoptosis, cell cycle arrest, drug-resistant reversion. 2. Oroxylin A possesses abilities of inhibiting the ATRA-induced IL-6 production v...		Virus Protease , HIF/HIF Prolyl-Hydroxylase , Autophagy
T5684	Ethyl 3,4-dihydroxybenzoate		Apoptosis , Others , Reactive Oxygen Species , HIF/HIF Prolyl-Hydroxylase , NO Synthase , Autophagy
	Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.
T1152	Albendazole	SKF-62979	HIF/HIF Prolyl-Hydroxylase , Microtubule Associated , Antibiotic , Parasite
	Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.
T2805	Chlorogenic Acid	NSC-407296,3-O-Caffeoylquinic acid,Heriguard	Others , Influenza Virus , Reactive Oxygen Species , HIF/HIF Prolyl-Hydroxylase , Endogenous Metabolite , Antibacterial
	Chlorogenic Acid (NSC-407296) is a naturally occurring phenolic acid which is a carcinogenic inhibitor. It has also been shown to prevent paraquat-induced oxidative stress in rats.
T2792	Glucosamine sulfate	D-Glucosamine sulphate,D-Glucosaminesulfate	MMP , Reactive Oxygen Species , HIF/HIF Prolyl-Hydroxylase , Endogenous Metabolite , Autophagy
	Glucosamine sulfate (D-Glucosaminesulfate) was extracted from synthetic product;Store the product in sealed, cool and dry condition.
T1205	Chloramphenicol	Chlornitromycin,Levomycetin,Chloromycetin	ribosome , HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic
	Chloramphenicol (Chloromycetin), a broad-spectrum antibiotic, blocks bacterial protein synthesis.
T11589	Hydroxycitric acid tripotassium hydrate	Potassium citrate monohydrate	ATP Citrate Lyase , HIF/HIF Prolyl-Hydroxylase , HIF
	Hydroxycitric acid tripotassium hydrate (Potassium citrate monohydrate) effectively inhibits stones formation and also inhibits HIF, and has antioxidation, anti-inflammation, and anti-tumor effects. Hydroxycitric acid tr...		ATP Citrate Lyase , HIF/HIF Prolyl-Hydroxylase , HIF
T2941	Glucosamine hydrochloride	Chitosamine hydrochloride,2-Amino-2-deoxy-glucose HCl,Chitosamine HCl,D-(+)-Glucosamine hydrochloride	Reactive Oxygen Species , HIF/HIF Prolyl-Hydroxylase , Endogenous Metabolite , Autophagy
	Glucosamine hydrochloride (Chitosamine hydrochloride) is commonly used as a treatment for osteoarthritis, although its acceptance as a medical therapy varies.
T0256	Citric acid trilithium salt tetrahydrate	Lithium citrate tribasic tetrahydrate,Trilithium citrate tetrahydrate	Dehydrogenase , GSK-3 , HIF/HIF Prolyl-Hydroxylase , Antibacterial , GluR
	Citric acid trilithium salt tetrahydrate (Lithium citrate tribasic tetrahydrate) , the active component of Lithium, is a medicine used in the therapy of psychiatric disease. It has shown the effects of signaling pathways...
T5S1569	AKBA	3-O-Acetyl-11-keto-β-boswellic acid,3-O-Acetyl-11-keto-beta-boswellic acid,Acetyl-11-keto-β-boswellic acid	Others , Reactive Oxygen Species , HIF/HIF Prolyl-Hydroxylase , Endogenous Metabolite
	AKBA (3-O-Acetyl-11-keto-beta-boswellic acid), a natural component from frankincense, is a novel activator of Nrf2.
T10233	Acetylarenobufagin		HIF
	Acetylarenobufagin is a steroidal hypoxia-inducible factor-1 (HIF-1) modulator.		HIF
T4S1725	Galanthamine	Galantamine	Apoptosis , AChE
	Galanthamine (Galantamine) is an acetylcholinesterase (AChE)inhibitor(IC50 : 500 nM), can reduce brain damage induced by hypoxia-ischemia.		Apoptosis , AChE
TN1916	Matairesinol		ATPase , p38 MAPK , ROS
	Matairesinol has radical and superoxide scavenging activities,; it also has anti-angiogenic activity by suppressing mROS signaling , can decrease hypoxia-inducible factor-1α± in hypoxic HeLa cells.		ATPase , p38 MAPK , ROS
T4S1050	Pristimerin	Celastrol methyl ester	NF-κB , Antibacterial
	1. Pristimerin (Celastrol methyl ester) has anticancer activity , treatment with Pristimerin may be a potential strategy for the suppression of hypoxia-induced metastasis through the reversal of hypoxia-induced stem cell...		NF-κB , Antibacterial
TN1096	Ginsenoside Ra1		Others , Tyrosine Kinases
	Ginsenoside Ra1 is a component from ginseng. Ginsenoside Ra1 shows significant inhibitory effects on protein tyrosine kinase (PTK) activation induced by hypoxia/reoxygenation (H/R).		Others , Tyrosine Kinases
T2808	Bilobalide	(-)-Bilobalide	Apoptosis , Endogenous Metabolite , Autophagy
	Bilobalide ((-)-Bilobalide), a bioactive from Gingko Biloba, is active on hypoxia-induced alterations.		Apoptosis , Endogenous Metabolite , Autophagy
TN1957	Mulberrofuran Q	MulberrofuranQ
	Mulberrofuran Q is an active compound that inhibits the formation of 12-hydroxy-5,8,10-heptadecatrienoic acid (HHT) and thromboxane B2 (cyclooxygenase product) , which protects neuronal cells from hypoxia-glycorrhoea-def...
T7050	Alpha-Tocopherolquinone	Metarene	Antioxidant
	During hypoxia in rats, levels of α-tocopherylquinon have been found to rise. alpha-Tocopherolquinone (Metarene) is reported to downregulate the respiratory activity of mitochondria. alpha-Tocopherolquinone has also disp...		Antioxidant
T4845	L-Lactic acid	2-HYDROXYPROPIONIC ACID,L-(+)-Lactic acid,(S)-2-Hydroxypropanoic acid	Endogenous Metabolite , Antibacterial , Antibiotic
	L-Lactic acid ((S)-2-Hydroxypropanoic acid) is a natural product produced by the anaerobic glycolysis of pyruvic acid. L-Lactic acid is a sensitive indicator of tissue hypoxia and can be used as a hemodynamic indicator i...		Endogenous Metabolite , Antibacterial , Antibiotic
T5702	Tenuifoliside B		Dehydrogenase
	Tenuifoliside B is a natural product from the roots of Polygala tenuifolia.And is a target lactate dehydrogenase inhibitor. Tenuifoliside B has cognitive improving and cerebral protective effects. it can inhibit potassi...		Dehydrogenase
T2946	Tanshinone IIA sulfonate sodium	Tanshinone IIA sulfonate,Sodium Tanshinone IIA sulfonate,Tanshinone IIA sodium sulfonate,sodium	CaMK , P450 , Calcium Channel
	Tanshinone IIA sulfonate sodium (Tanshinone IIA sodium sulfonate) is a water-soluble derivative of tanshinone IIA extracted from Savia miltiorrhiza; a potent negative allosteric modulator of the human purinergic receptor...		CaMK , P450 , Calcium Channel
TWS1977	Kamebakaurin	Kamebakaurine	NF-κB
	1. Kamebakaurin (Kamebakaurine) has the ability to protect the liver from APAP-induced hepatotoxicity, presumably by both inhibiting the inflammatory response and oxidative stress. 2. Kamebakaurin inhibits the expression...		NF-κB
TN6945	Lactic acid	2-hydroxypropanoic acid	Others
	Lactic acid (2-hydroxypropanoic acid) is a product of glycolysis and is widely found in nature.Lactic acid is produced in the body during hypoxia in contracted skeletal muscle and can be removed under fully aerobic condi...		Others
T3822	Bellidifolin	Bellidifoline,Bellidifolium	Others , HIV Protease
	Bellidifolin (Bellidifoline) has anti-oxidation, hepatoprotective, anti-inflammatory and antitumor actions, it may contribute to the protective effects associated with nerve injury initiated by hypoxia by mechanisms rela...		Others , HIV Protease
T4S0800	Demethyleneberberine		P450 , NOS , NF-κB , HIF , AMPK
	Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria either in vitro or in vivo.Demethyleneberberine suppresses CYP2E1,...		P450 , NOS , NF-κB , HIF , AMPK
T6429	Caffeic Acid Phenethyl Ester	Phenylethyl Caffeate,CAPE	Apoptosis , NF-κB
	Caffeic Acid Phenethyl Ester (Phenylethyl Caffeate) (CAPE) inhibits the activation of nuclear transcription factor NF-kappa B and may suppress p70S6K and Akt-driven signaling pathways, with antineoplastic, cytoprotective...		Apoptosis , NF-κB
T2S0843	Negletein	7-O-Methylbaicalein,Baicalein-7-methylether	IL Receptor , TNF , NOS , Interleukin
	1. Negletein (7-O-Methylbaicalein) has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. 2. Negletein as a neuroprotectant enhances the action of nerve growth factor and induces n...		IL Receptor , TNF , NOS , Interleukin
TN6417	N-Methylcorydalmine
	N-Methylcorydalmine may exhibit significant anti-hypoxia activity.
T6569L	Mimocine	Mimocine
	Mimosine, a plant amino acid, is known to act as a normoxic inducer of hypoxia-inducible factor (HIF).
TN1952	Moracin P		Others , ROS , HIF
	Moracin P exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1), which is a key mediator during adaptation of cancer cells to tumour hypoxia.		Others , ROS , HIF
T13582	Bisandrographolide C		Others
	Bisandrographolide C is identified from Andrographis paniculata. Bisandrographolide C activates TRPV1 and TRPV3 channels (Kds: 289 and 341 μM) and protects cardiomyocytes from hypoxia-reoxygenation injury.		Others
TN1951	Moracin O		HIF
	Moracin O shows significant neuroprotective, and analgesic activities, it also has a strong protective influence against doxorubicin-induced cardiomyopathy in H9c2 cells with the EC50 value of 4.5 ± 1.3 μM. Moracin O exh...		HIF
T75487	7-Hydroxyneolamellarin A
	7-Hydroxyneolamellarin A, a natural product from the sponge Dendrilla nigra, serves as a potent inhibitor of hypoxia-inducible factor-1α (HIF-1α). It effectively reduces the accumulation of HIF-1α protein and suppresses ...
T36439	Gramicidin A		Antibacterial , HIF , Parasite
	Gramicidin A is a peptide antibiotic isolated from B. brevis.Gramicidin A is a highly hydrophobic channel-forming ion carrier that forms monovalent cation-permeable channels in artificial membranes.Gramicidin A induces t...		Antibacterial , HIF , Parasite

天然物製品

Fraxinellone

T6S0071

Synonym:

Target: HIF/HIF Prolyl-Hydroxylase, STAT, PD-1/PD-L1

Deoxyshikonin

T5S2347

Synonym: Arnebin 7

Target: Others, HIF/HIF Prolyl-Hydroxylase, Antibacterial

dencichine

TL0001

Synonym: L-Dencichin,ODAP,Dencichin

Target: Others, HIF/HIF Prolyl-Hydroxylase

Moslosooflavone

T5773

Synonym: 5-hydroxy-7,8-dimethoxyflavone

Target: NF-κB, Reactive Oxygen Species

Panaxadiol

T2763

Synonym: 20(R)-Panaxadiol

Target: Others, HIF/HIF Prolyl-Hydroxylase

Glucosamine

T0429

Synonym: Chitosamine,D-Glucosamine

Target: MMP, Others, TNF, NF-κB, Reactive Oxygen Species, HIF/HIF Prolyl-Hydroxylase, Endogenous Metabolite, CFTR, Autophagy

Oroxylin A

T6S1315

Synonym: 6-Methoxybaicalein,Baicalein 6-methyl ether

Target: Virus Protease, HIF/HIF Prolyl-Hydroxylase, Autophagy

Ethyl 3,4-dihydroxybenzoate

T5684

Synonym:

Target: Apoptosis, Others, Reactive Oxygen Species, HIF/HIF Prolyl-Hydroxylase, NO Synthase, Autophagy

Albendazole

T1152

Synonym: SKF-62979

Target: HIF/HIF Prolyl-Hydroxylase, Microtubule Associated, Antibiotic, Parasite

Chlorogenic Acid

T2805

Synonym: NSC-407296,3-O-Caffeoylquinic acid,Heriguard

Target: Others, Influenza Virus, Reactive Oxygen Species, HIF/HIF Prolyl-Hydroxylase, Endogenous Metabolite, Antibacterial

Glucosamine sulfate

T2792

Synonym: D-Glucosamine sulphate,D-Glucosaminesulfate

Target: MMP, Reactive Oxygen Species, HIF/HIF Prolyl-Hydroxylase, Endogenous Metabolite, Autophagy

Chloramphenicol

T1205

Synonym: Chlornitromycin,Levomycetin,Chloromycetin

Target: ribosome, HIF/HIF Prolyl-Hydroxylase, Antibacterial, Antibiotic

Hydroxycitric acid tripotassium hydrate

T11589

Synonym: Potassium citrate monohydrate

Target: ATP Citrate Lyase, HIF/HIF Prolyl-Hydroxylase, HIF

Glucosamine hydrochloride

T2941

Synonym: Chitosamine hydrochloride,2-Amino-2-deoxy-glucose HCl,Chitosamine HCl,D-(+)-Glucosamine hydrochloride

Target: Reactive Oxygen Species, HIF/HIF Prolyl-Hydroxylase, Endogenous Metabolite, Autophagy

Citric acid trilithium salt tetrahydrate

T0256

Synonym: Lithium citrate tribasic tetrahydrate,Trilithium citrate tetrahydrate

Target: Dehydrogenase, GSK-3, HIF/HIF Prolyl-Hydroxylase, Antibacterial, GluR

AKBA

T5S1569

Synonym: 3-O-Acetyl-11-keto-β-boswellic acid,3-O-Acetyl-11-keto-beta-boswellic acid,Acetyl-11-keto-β-boswellic acid

Target: Others, Reactive Oxygen Species, HIF/HIF Prolyl-Hydroxylase, Endogenous Metabolite

Target: Apoptosis, AChE

Matairesinol

TN1916

Synonym:

Target: ATPase, p38 MAPK, ROS

Pristimerin

T4S1050

Synonym: Celastrol methyl ester

Target: NF-κB, Antibacterial

Ginsenoside Ra1

TN1096

Synonym:

Target: Others, Tyrosine Kinases

Bilobalide

T2808

Synonym: (-)-Bilobalide

Target: Apoptosis, Endogenous Metabolite, Autophagy

Mulberrofuran Q

TN1957

Synonym: MulberrofuranQ

Target:

alpha-Tocopherolquinone

Synonym: 2-HYDROXYPROPIONIC ACID,L-(+)-Lactic acid,(S)-2-Hydroxypropanoic acid

Target: Endogenous Metabolite, Antibacterial, Antibiotic

Tenuifoliside B

T5702

Synonym:

Target: Dehydrogenase

Tanshinone IIA sulfonate sodium

T2946

Synonym: Tanshinone IIA sulfonate,Sodium Tanshinone IIA sulfonate,Tanshinone IIA sodium sulfonate,sodium

Target: CaMK, P450, Calcium Channel

Kamebakaurin

TWS1977

Synonym: Kamebakaurine

Target: NF-κB

Lactic acid

TN6945

Synonym: 2-hydroxypropanoic acid

Target: Others

Bellidifolin

T3822

Synonym: Bellidifoline,Bellidifolium

Target: Others, HIV Protease

Demethyleneberberine

T4S0800

Synonym:

Target: P450, NOS, NF-κB, HIF, AMPK

Caffeic Acid Phenethyl Ester

T6429

Synonym: Phenylethyl Caffeate,CAPE

Target: Apoptosis, NF-κB

Negletein

T2S0843

Synonym: 7-O-Methylbaicalein,Baicalein-7-methylether

Target: IL Receptor, TNF, NOS, Interleukin

Target: Others, ROS, HIF

7-Hydroxyneolamellarin A

Target: Antibacterial, HIF, Parasite

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-01577	ORP150 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Hypoxia up-regulated protein 1, also known as 15 kDa oxygen-regulated protein, 17 kDa glucose-regulated protein, ORP-15, GRP-17, and HYOU1, is a member of the heat shock protein 7 family. Seven members from four differen...
TMPY-01709	HIF-1 alpha Protein, Human, Recombinant (His)	Human	E. coli
	HIF-1 alpha, also known as HIF1A, contains 1 basic helix-loop-helix (bHLH) domain, 1 PAC (PAS-associated C-terminal) domain, and 2 PAS (PER-ARNT-SIM) domains. It is one of the two subunits of Hypoxia-inducible factor-1 (...
TMPH-00957	ARNT Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	ARNT Protein, Human, Recombinant (His) is expressed in Yeast.
TMPJ-00071	EPO/Erythropoietin Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Erythropoietin (EPO) is a glycoprotein hormone that is principally known for its role in erythropoiesis, where it is responsible for stimulating proliferation and differentiation of erythroid progenitor cells. Erythropoi...
TMPK-00563	EPHB2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	EphB2, a receptor tyrosine kinase for ephrin ligands, is overexpressed in various cancers and plays an important role in tumor progression. EPHB2 promotes endothelial-mesenchymal transition (EMT) and elicits associated p...
TMPY-01576	Artemin Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Artemin (ARTN) is a member of glial cell line-derived neurotrophic factor (GDNF) family of ligands, and its signaling is mediated via a multi-component receptor complex including the glycosylphosphatidylinositol-anchored...
TMPY-04270	GPR133 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	ADGRD1 (Adhesion G Protein-Coupled Receptor D1, also known as GPR133) is a Protein Coding gene. 4 alternatively spliced human isoforms have been reported. ADGRD1, an orphan member of the adhesion family of G-protein-coup...
TMPH-02233	P4HTM Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic...
TMPY-02378	14‑3‑3 theta/YWHAQ Protein, Human, Recombinant (GST)	Human	E. coli
	The recently identified 14-3-3 tau, whose corresponding gene name is YWHAQ, is in a hypoxia-treated human trophoblast cell line. YWHAQ may play a role in epigenetic regulation of placental genes in the onset of Preeclamp...
TMPK-00923	FAP Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Fibroblast activation protein (FAP) is a serine protease that has been reported in fibroblasts and some carcinoma cells, which correlates with poor patient outcomes. FAP can be induced under hypoxia which is also vital i...
TMPH-01280	EGLN1 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of th...
TMPK-01282	FAP Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated	Cynomolgus	HEK293 Cells
	Fibroblast activation protein (FAP) is a serine protease that has been reported in fibroblasts and some carcinoma cells, which correlates with poor patient outcomes. FAP can be induced under hypoxia which is also vital i...
TMPK-00373	FAP Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Fibroblast activation protein (FAP) is a serine protease that has been reported in fibroblasts and some carcinoma cells, which correlates with poor patient outcomes. FAP can be induced under hypoxia which is also vital i...
TMPK-00524	CA9/Carbonic Anhydrase IX Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	CA9 is a member of the carbonic anhydrases' family, that is often expressed in cancer cells under hypoxic condition. CA9 expression potentially contributes to the regulation of cancer cell differentiation and mediates tu...
TMPK-00283	CA9/Carbonic Anhydrase IX Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	CA9 is a member of the carbonic anhydrases' family, that is often expressed in cancer cells under hypoxic condition. CA9 expression potentially contributes to the regulation of cancer cell differentiation and mediates tu...
TMPK-00658	IGF1R/CD221 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, prot...
TMPK-00455	IGF1R/CD221 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, prot...
TMPH-02505	ENO1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Glycolytic enzyme the catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate. In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May ...
TMPK-00456	IGF1R/CD221 Protein, Human, Recombinant (aa 31-932, His & Avi), Biotinylated	Human	HEK293 Cells
	The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, prot...
TMPJ-00999	UBE2D1 Protein, Human, Recombinant (GST)	Human	E. coli
	Ubiquitin-conjugating enzyme E2 D1（UBE2D1）belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes...
TMPY-04671	MCP-5 Protein, Mouse, Recombinant (His)	Mouse	P. pastoris (Yeast)
	Ccl12 prevented initiation of the reparative response by prolonging inflammation and inhibiting fibroblast conversion to myofibroblasts, resulting in diminished scar formation. Macrophage secretion of Ccl12 directly impa...
TMPJ-00283	Carbonic Anhydrase 9 Protein, Human, Recombinant (Avi & His), Biotinylated	Human	HEK293 Cells
	Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzym...
TMPJ-01415	ANGPTL4 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Angiopoietin-related protein 4（ANGPTL4）is a secreted protein and contains 1 fibrinogen C-terminal domain. The protein may act as a regulator of angiogenesis and modulate tumorigenesis. It inhibits proliferation, migratio...
TMPY-02376	BNIP3L Protein, Human, Recombinant	Human	E. coli
	The deletion of BNIP3L results in retention of mitochondria during lens fiber cell remodeling, and that deletion of BNIP3L also results in the retention of endoplasmic reticulum and Golgi apparatus. BNIP3L localizes to t...
TMPY-04474	PFKFB3 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Fructose-2,6-biphosphatase 3, also known as 6-phosphofructo-2-kinase or PFK2 or PFKFB3, is a potent activator of phosphofructokinase, which is a rate-limiting enzyme of glycolysis. Highly phosphorylated PFKFB3 protein wa...
TMPY-00920	SFRP2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	The Secreted frizzled-related protein (SFRP) family consists of five secreted glycoproteins in humans (SFRP1~5) that act as extracellular signaling ligands. Each SFRP is approximately 3 amino acids in length and contains...
TMPY-01000	BVES Protein, Human, Recombinant (GST)	Human	E. coli
	Blood vessel epicardial substance (BVES), or POPDC1, is a tight junction-associated transmembrane protein that modulates epithelial-to-mesenchymal transition (EMT) via junctional signaling pathways. BVES plays a protecti...
TMPY-02228	P53 Protein, Cynomolgus, Recombinant	Cynomolgus	E. coli
	p53, also known as Tp53, is a DNA-binding protein which belongs to the p53 family. It contains transcription activation, DNA-binding, and oligomerization domains. p53 protein is expressed at low level in normal cells and...

ORP150 Protein, Human, Recombinant (His)

TMPY-01577

Species: Human

Expression System: HEK293 Cells

HIF-1 alpha Protein, Human, Recombinant (His)

TMPY-01709

Species: Human

Expression System: E. coli

ARNT Protein, Human, Recombinant (His)

TMPH-00957

Species: Human

Expression System: P. pastoris (Yeast)

EPO/Erythropoietin Protein, Human, Recombinant (His)

TMPJ-00071

Species: Human

Expression System: HEK293 Cells

EPHB2 Protein, Cynomolgus, Recombinant (His)

TMPK-00563

Species: Cynomolgus

Expression System: HEK293 Cells

Artemin Protein, Mouse, Recombinant (hFc)

TMPY-01576

Species: Mouse

Expression System: HEK293 Cells

GPR133 Protein, Human, Recombinant (His)

TMPY-04270

Species: Human

Expression System: HEK293 Cells

P4HTM Protein, Human, Recombinant (His & SUMO)

TMPH-02233

Species: Human

Expression System: E. coli

14‑3‑3 theta/YWHAQ Protein, Human, Recombinant (GST)

TMPY-02378

Species: Human

Expression System: E. coli

FAP Protein, Mouse, Recombinant (His)

TMPK-00923

Species: Mouse

Expression System: HEK293 Cells

EGLN1 Protein, Human, Recombinant (His & Myc)

TMPH-01280

Species: Human

Expression System: E. coli

FAP Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated

TMPK-01282

Species: Cynomolgus

Expression System: HEK293 Cells

FAP Protein, Human, Recombinant (hFc)

TMPK-00373

Species: Human

Expression System: HEK293 Cells

CA9/Carbonic Anhydrase IX Protein, Cynomolgus, Recombinant (His)

TMPK-00524

Species: Cynomolgus

Expression System: HEK293 Cells

CA9/Carbonic Anhydrase IX Protein, Human, Recombinant (His & Avi)

TMPK-00283

Species: Human

Expression System: HEK293 Cells

IGF1R/CD221 Protein, Cynomolgus, Recombinant (His)

TMPK-00658

Species: Cynomolgus

Expression System: HEK293 Cells

IGF1R/CD221 Protein, Human, Recombinant (His & Avi)

TMPK-00455

Species: Human

Expression System: HEK293 Cells

ENO1 Protein, Mouse, Recombinant (His)

TMPH-02505

Species: Mouse

Expression System: E. coli

IGF1R/CD221 Protein, Human, Recombinant (aa 31-932, His & Avi), Biotinylated

TMPK-00456

Species: Human

Expression System: HEK293 Cells

UBE2D1 Protein, Human, Recombinant (GST)

TMPJ-00999

Species: Human

Expression System: E. coli

MCP-5 Protein, Mouse, Recombinant (His)

TMPY-04671

Species: Mouse

Expression System: P. pastoris (Yeast)

Carbonic Anhydrase 9 Protein, Human, Recombinant (Avi & His), Biotinylated

TMPJ-00283

Species: Human

Expression System: HEK293 Cells

ANGPTL4 Protein, Mouse, Recombinant (hFc)

TMPJ-01415

Species: Mouse

Expression System: HEK293 Cells

BNIP3L Protein, Human, Recombinant

TMPY-02376

Species: Human

Expression System: E. coli

PFKFB3 Protein, Human, Recombinant (His & GST)

TMPY-04474

Species: Human

Expression System: Baculovirus Insect Cells

SFRP2 Protein, Mouse, Recombinant (His)

TMPY-00920

Species: Mouse

Expression System: HEK293 Cells

BVES Protein, Human, Recombinant (GST)

TMPY-01000

Species: Human

Expression System: E. coli

p53 Protein, Cynomolgus, Recombinant

TMPY-02228

Species: Cynomolgus

Expression System: E. coli

カタログ番号	製品名
L8500	HIF-1 Signaling Pathway Compound Library	1336 compounds
	A unique collection of 1336 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies；
L9700	Endoplasmic Reticulum Stress Compound Library	193 compounds
	A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS);
L2501	Human Endogenous Metabolite Compound Library Plus	1283 compounds

ライブラリー

HIF-1 Signaling Pathway Compound Library

L8500

Compounds: 1336

Endoplasmic Reticulum Stress Compound Library

L9700

Compounds: 193

Human Endogenous Metabolite Compound Library Plus

L2501

Compounds: 1283