| TMPY-02585
|
Acid sphingomyelinase/SMPD1 Protein, Mouse, Recombinant (His)
|
Mouse |
Baculovirus Insect Cells |
|
Sphingomyelin phosphodiesterase 1 (SMPD1) , also known as ASM ( acid sphingomyelinase ), is a member of the acid sphingomyelinase family of enzymes. Three isoforms have been identified, isoform 1 is 631 amino acids (aa) ... |
| TMPY-01813
|
ACRV1 Protein, Human, Recombinant (His)
|
Human |
HEK293 Cells |
|
Acrosomal protein SP-1, also known as Acrosomal vesicle protein 1 and ACRV1, is a testis-specific, differentiation antigen, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the a... |
| TMPH-00585
|
Beta-lactamase CTX-M-1 Protein, E. coli, Recombinant (Yeast, His)
|
E. coli |
P. pastoris (Yeast) |
|
Broad spectrum beta-lactamase which confers resistance to penicillins, as well as first, second and third-generation cephalosporins. |
| TMPH-00584
|
Beta-lactamase CTX-M-1 Protein, E. coli, Recombinant (His)
|
E. coli |
E. coli |
|
Broad spectrum beta-lactamase which confers resistance to penicillins, as well as first, second and third-generation cephalosporins. |
| TMPH-02817
|
OTCase Protein, Mouse, Recombinant (His & SUMO)
|
Mouse |
E. coli |
|
Catalyzes the second step of the urea cycle, the condensation of carbamoyl phosphate with L-ornithine to form L-citrulline. The urea cycle ensures the detoxification of ammonia by converting it to urea for excretion. |
| TMPJ-00190
|
CD38 Protein, Mouse, Recombinant (hFc)
|
Mouse |
HEK293 Cells |
|
CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicoti... |
| TMPH-01294
|
EDNRA Protein, Human, Recombinant (His)
|
Human |
P. pastoris (Yeast) |
|
Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3. |
| TMPH-00722
|
PykF Protein, E. coli, Recombinant (His)
|
E. coli |
E. coli |
|
Catalyzes the formation of pyruvate in the last step of glycolysis, it is irreversible under physiological conditions. The reaction is critical for the control of metabolic flux in the second part of glycolysis. |
| TMPH-00574
|
Adenylate cyclase Protein, E. coli, Recombinant (His)
|
E. coli |
E. coli |
|
Catalyzes the formation of the second messenger cAMP from ATP. Its transcript is probably degraded by endoribonuclease LS (rnlA), decreasing cAMP levels and the negative regulator Crp-cAMP, which then induces its own tra... |
| TMPH-00654
|
Methionine aminopeptidase Protein, E. coli, Recombinant (His & SUMO)
|
E. coli |
E. coli |
|
Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requ... |
| TMPH-03029
|
MetAP Protein, Mycoplasma pneumoniae, Recombinant (His & SUMO)
|
Mycoplasma pneumoniae |
E. coli |
|
Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requ... |
| TMPJ-00979
|
GSH-S Protein, Human, Recombinant (His)
|
Human |
E. coli |
|
Glutathione Synthetase belongs to the eukaryotic GSH synthase family. Glutathione Synthetase is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glyci... |
| TMPH-01817
|
OTCase Protein, Human, Recombinant (His & SUMO)
|
Human |
E. coli |
|
Catalyzes the second step of the urea cycle, the condensation of carbamoyl phosphate with L-ornithine to form L-citrulline. The urea cycle ensures the detoxification of ammonia by converting it to urea for excretion. OTC... |
| TMPH-02680
|
QPCT Protein, Mouse, Recombinant (His & Myc)
|
Mouse |
HEK293 Cells |
|
Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue... |
| TMPH-02679
|
QPCT Protein, Mouse, Recombinant (His)
|
Mouse |
P. pastoris (Yeast) |
|
Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue... |
| TMPH-00667
|
OGDC-E2 Protein, E. coli O157:H7, Recombinant (His)
|
E. coli |
E. coli |
|
E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). OGDC-E2 Protein, E. coli O157:H7, Recombinant (His) is expres... |
| TMPH-02905
|
TRPC1 Protein, Mouse, Recombinant (His)
|
Mouse |
E. coli |
|
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled recep... |
| TMPH-02147
|
TACR1 Protein, Human, Recombinant (GST)
|
Human |
E. coli |
|
This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor ... |
| TMPH-03749
|
CYSLTR1 Protein, Human, Recombinant (His)
|
Human |
E. coli |
|
Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and... |
| TMPY-02977
|
PDE1C Protein, Human, Recombinant (His & GST)
|
Human |
Baculovirus Insect Cells |
|
PDE1C belongs to the cyclic nucleotide phosphodiesterase family, PDE1 subfamily. Phosphodiesterases (PDEs) are a family of related phosphohydrolyases that selectively catalyze the hydrolysis of 3' cyclic phosphate bonds ... |
| TMPH-02139
|
CYP17A1 Protein, Human, Recombinant (GST)
|
Human |
E. coli |
|
A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen sy... |
| TMPY-02081
|
PDE2A Protein, Human, Recombinant (aa 215-900, His)
|
Human |
Baculovirus Insect Cells |
|
cGMP-dependent 3',5'-cyclic phosphodiesterase, also known as cyclic GMP-stimulated phosphodiesterase and PDE2A, is a peripheral membrane protein that belongs to the cyclic nucleotide phosphodiesterase family and PDE2 sub... |
| TMPH-02141
|
CYP21A2 Protein, Human, Recombinant (His)
|
Human |
P. pastoris (Yeast) |
|
A cytochrome P450 monooxygenase that plays a major role in adrenal steroidogenesis. Catalyzes the hydroxylation at C-21 of progesterone and 17alpha-hydroxyprogesterone to respectively form 11-deoxycorticosterone and 11-d... |
| TMPH-01663
|
GRM5 Protein, Human, Recombinant (His & Myc)
|
Human |
E. coli |
|
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Sign... |
| TMPH-01023
|
C5AR1 Protein, Human, Recombinant (Cell-Free, His)
|
Human |
E. coli |
|
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transm... |
| TMPH-01022
|
C5AR1 Protein-VLP, Human, Recombinant (His)
|
Human |
HEK293 Cells |
|
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transm... |
| TMPJ-01117
|
INPP5A Protein, Human, Recombinant (His)
|
Human |
HEK293 Cells |
|
Type I inositol 1,4,5-trisphosphate 5-phosphatase is a 412 amino acids protein that belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family. Type I inositol-1,4,5-trisphosphate 5-phosphatase is an enzyme ... |
| TMPJ-01271
|
PIK3IP1 Protein, Human, Recombinant (His)
|
Human |
HEK293 Cells |
|
Phosphoinositide-3-kinase-interacting protein 1(PIK3IP1) is an enzyme that in humans is encoded by the PIK3IP1 gene.It is a negative regulator of phosphatidylinositol-3-kinase (PI3K), suppresses the development of hepato... |
| TMPH-01205
|
DCAF7 Protein, Human, Recombinant (His)
|
Human |
E. coli |
|
Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the f... |
| TMPH-03018
|
MeTAP1 Protein, Mycobacterium tuberculosis, Recombinant (His)
|
Mycobacterium tuberculosis |
E. coli |
|
Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requ... |
| TMPK-00521
|
PSMA Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus |
HEK293 Cells |
|
Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate... |
| TMPK-00166
|
PD-L2 Protein, Human, Recombinant (His & Avi)
|
Human |
HEK293 Cells |
|
PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine pr... |
| TMPH-01346
|
FPR1 Protein, Human, Recombinant (GST & His & Myc)
|
Human |
E. coli |
|
High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release... |
| TMPH-03460
|
ERG26 Protein, S. cerevisiae, Recombinant (His & Myc)
|
SVG-Saccharomyces cerevisiae |
E. coli |
|
Essential enzyme in the ergosterol biosynthetic pathway. Part of a 3 enzyme system that catalyzes the sequential removal of the 2 methyl groups at the sterol C-4 position, converting 4,4-dimethylzymosterol to zymosterol.... |
| TMPH-02677
|
GPI Protein, Mouse, Recombinant (B2M & His)
|
Mouse |
E. coli |
|
In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis. Besides it's role as a glycolytic enzyme, also ac... |
| TMPH-02140
|
CYP21A2 Protein, Human, Recombinant (E. coli, His)
|
Human |
E. coli |
|
A cytochrome P450 monooxygenase that plays a major role in adrenal steroidogenesis. Catalyzes the hydroxylation at C-21 of progesterone and 17alpha-hydroxyprogesterone to respectively form 11-deoxycorticosterone and 11-d... |
| TMPH-02618
|
CYP2E1 Protein, Mouse, Recombinant (His)
|
Mouse |
E. coli |
|
A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electr... |
| TMPH-00589
|
SpoT Protein, E. coli, Recombinant (His & Myc)
|
E. coli |
E. coli |
|
In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response which coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme cataly... |
| TMPH-02675
|
GCGR Protein, Mouse, Recombinant (GST)
|
Mouse |
E. coli |
|
G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and g... |
| TMPH-02678
|
GPI Protein, Mouse, Recombinant (His)
|
Mouse |
P. pastoris (Yeast) |
|
In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis. Besides it's role as a glycolytic enzyme, also ac... |
| TMPH-01065
|
CCR4 Protein-VLP, Human, Recombinant (His)
|
Human |
HEK293 Cells |
|
High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger... |
| TMPH-01064
|
CCR4 Protein, Human, Recombinant (His & SUMO)
|
Human |
E. coli |
|
High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger... |
| TMPK-01290
|
PD-L2 Protein, Cynomolgus, Recombinant (aa 20-220, His)
|
Cynomolgus |
HEK293 Cells |
|
PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine pr... |
| TMPK-00370
|
PSMA Protein, Human, Recombinant (hFc)
|
Human |
HEK293 Cells |
|
Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate... |
| TMPH-02658
|
FPR1 Protein, Mouse, Recombinant (GST & His & Myc)
|
Mouse |
E. coli |
|
High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release... |
| TMPK-00371
|
PSMA Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated
|
Mouse |
HEK293 Cells |
|
Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate... |
| TMPK-00941
|
TFF1 Protein, Mouse, Recombinant (hFc)
|
Mouse |
HEK293 Cells |
|
Breast cancer (BC) is the most common cancer in women and the second leading cause of their cancer death. Establishing an accurate BC prognosis is very difficult because of its heterogeneity. Elevated TFF1 levels in seru... |
| TMPH-01391
|
GPI Protein, Human, Recombinant (His)
|
Human |
E. coli |
|
In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis. Besides it's role as a glycolytic enzyme, also ac... |
| TMPJ-00732
|
ASS1 Protein, Human, Recombinant (His)
|
Human |
E. coli |
|
Argininosuccinate Synthase (ASS1) is an urea cycle enzyme with a tetrameric structure composed of identical subunits. ASS1 is involved in the synthesis of arginine and catalyzes that condensation of citrulline and aspart... |
| TMPH-01222
|
DGKA Protein, Human, Recombinant (His)
|
Human |
E. coli |
|
Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pa... |
