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Search Results for " SRC "

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天然化合物

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カタログ番号	製品名	別名	ターゲット
T3593	Src Inhibitor 1	Src Kinase Inhibitor 1,Src-l1	Src
	Src Inhibitor 1 (Src Kinase Inhibitor 1) is a potent and selective dual site Src tyrosine kinase inhibitor.		Src
TP2289L	RR-src acetate	RR-src acetate(81156-93-6 Free base)	Others
	RR-src acetate is a synthetic peptide derived from the amino acid sequence surrounding the phosphorylation site in pp60src.		Others
T13000	Src Inhibitor 3		Others , Src
			Others , Src
T11745	KB SRC 4		Src
	KB SRC 4 is a selective and potent c-Src inhibitor with antitumour activity that inhibits the growth of cancer cells.		Src
TP2137L	Pp60 c-src (521-533) (phosphorylated) acetate		Others
	pp60 c-src (521-533) (phosphorylated) acetate is a regulator of focal adhesion formation and cell spreading. pp60 c-src (521-533) (phosphorylated) acetate also regulates cell motility and is a key component in the signal...		Others
T39185	Pp60 (v-SRC) Autophosphorylation Site, Phosphorylated	pp60 (v-SRC) Autophosphorylation Site, Phosphorylated
	pp60 (v-SRC) Autophosphorylation Site, Phosphorylated is a phosphorylated peptide derived from an EGFR substrate. It serves as a valuable tool for quantifying phosphorylated substrates in screening EGFR Kinase inhibitors...
T39149	Src Optimal Peptide Substrate
	Src Optimal Peptide Substrate, a highly specific substrate of Src, serves as a reliable indicator of Src activity. It enables accurate assessment of Src kinase function.
T1811	WH-4-023	KIN112,KIN001-112,Dual LCK/SRC inhibitor	Src
	WH-4-023 (Dual LCK/SRC inhibitor) is a potent and orally active Lck/Src inhibitor. It also potently inhibits SIK.		Src
TP2289	RR-src		Others
	Tyrosine kinase substrate peptide		Others
T13062	T338C Src-IN-2		Others
	T338C Src-IN-2 is a potent mutant inhibitor of c-Src T338C kinase(IC50 of 317 nM). T338C Src-IN-2 also inhibits T338C/V323A and T338C/V323S(IC50 of 57 nM/19 nM,respectively).		Others
T13061	T338C Src-IN-1		Others
	T338C Src-IN-1 is a potent mutant-Src T338C inhibitor(T338C,IC50=111 nM relative to WT c-Src (10-fold increase)).		Others
TP2137	Pp60 c-src (521-533) (phosphorylated)
	Peptide corresponding to the pp60c-src carboxy terminal regulatory domain; phosphorylated at Tyr527. Binds to pp60c-src and pp60v-src at the SH2 domain, suppressing their tyrosine kinase activity and transforming potenti...
T76391	P60c-src substrate II
	P60c-src substrate II is a potent pentapeptide substrate for the tyrosine kinase pp60c-src [1].
T81578	P60c-src substrate II, phosphorylated
	Phosphorylated p60c-src substrate II is a pentapeptide and a phosphorylated polypeptide form of p60c-src substrate II. Phosphorylation is a critical post-translational modification (post-translationmodification) vital fo...
T81577	P60v-src(137-157)
	P60v-src(137-157) is a synthetic peptide that serves as an inhibitor of the tyrosine kinase activity of p60 v-src, with an IC50 value of 7.5 μM [1] [2].
T81106	SRC-1 (686-700)
	SRC-1 (686-700) is a bioactive peptide encompassing amino acids 686 to 700, which include the second LXXLL motif from NR box II of steroid receptor coactivator (SRC1). These coactivator proteins facilitate transcription ...
T83752	Biotin-SRC-1 (676–700) TFA	Biotin-Steroid Receptor Coactivator 1 (676-700)
	Biotin-SRC-1 (676–700), a biotinylated and truncated variant of steroid receptor coactivator 1 (SRC-1), finds application in affinity-based reporter assays such as time-resolved FRET (TR-FRET) and amplified luminescent p...
T0152	Bosutinib	SKI-606	Bcr-Abl , Src , Autophagy
	Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases.		Bcr-Abl , Src , Autophagy
T8499	ECF506		Src
	eCF506 is a potent and selective inhibitor of SRC (IC50 < 0.5 nM)		Src
T17267	XL228		IGF-1R , Bcr-Abl , Src , Aurora Kinase
	XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).		IGF-1R , Bcr-Abl , Src , Aurora Kinase
T3063	PD173955	PD-173955,PD 173955	Apoptosis , Bcr-Abl , Src
	PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase; less potent for FGFRα and no activity on InsR and PKC.		Apoptosis , Bcr-Abl , Src
T13186	TL02-59		Apoptosis , Src , Hck
			Apoptosis , Src , Hck
T6078	Saracatinib	AZD0530	EGFR , Src , BTK , Autophagy
	Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes.		EGFR , Src , BTK , Autophagy
T4470	Pyridostatin TFA		DNA/RNA Synthesis
	Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-kit, K-ras and Bcl-2.		DNA/RNA Synthesis
T4301	AD80		Raf , c-RET , Src , S6 Kinase
	AD80, a multikinase inhibitor, inhibits RET, RAF, SRCand S6K, with greatly reduced mTOR activity.		Raf , c-RET , Src , S6 Kinase
T16760	RK-24466	KIN 001-51	Src
	RK-24466 (KIN 001-51) is a selective and potent inhibitor of Lck, inhibits Lck (64-509) and LckCD isoforms with IC50s of less than 1 and 2 nM, respectively.		Src
T6594	MNS		Syk , Src , p97
	MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.		Syk , Src , p97
T6345	Tirbanibulin	KX2-391,KX-01	Microtubule Associated , Src
	Tirbanibulin (KX2-391) is a highly selective Src kinase inhibitor that has demonstrated efficacy in pre-Clinicalal animal models of colon, pancreatic, prostate and breast cancer. It is a substrate-targeted kinase inhibit...		Microtubule Associated , Src
T11538	Hck-IN-1		HIV Protease , Src , Hck
	Hck-IN-1 is a selective Nef-dependent Hck inhibitor (IC50s: 2.8 μM and >20 μM for Nef:Hck complex and Hck) with antiretroviral activity. Hck-IN-1 is a direct and wide HIV-1 Nef antagonist with an IC50 of 100-300 nM for w...		HIV Protease , Src , Hck
T4597	UM-164	UM164,DAS-DFGO-II	p38 MAPK , Src , Autophagy
	UM-164 (DAS-DFGO-II), a highly potent c-Src inhibitor with a dissociation constant (Kd) of 2.7 nM, also effectively inhibits p38α and p38β.		p38 MAPK , Src , Autophagy
T13194	CSF1R-IN-2		c-Fms , c-Met/HGFR , Src
	CSF1R-IN-2 is an oral-active SRC, MET and c-FMS inhibitor (IC50s: 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively).		c-Fms , c-Met/HGFR , Src
T2153	1-NM-PP1	PP1 Analog II,1 nM-PP1	Serine/threonin kinase , CDK , Src
	1-NM-PP1 (PP1 Analog II) is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors.		Serine/threonin kinase , CDK , Src
T6997	SU6656		FAK , Akt , Src
	SU 6656 is a selective inhibitor of Src family kinases, with IC50 of 280 nM, 20 nM, 130 nM, and 170 nM for Src, Yes, Lyn, and Fyn, respectively.		FAK , Akt , Src
T2415	PP121		Apoptosis , VEGFR , Bcr-Abl , PDGFR , Src , mTOR , Hck
	PP-121 is a multi-targeted inhibitor of PDGFR (IC50: 2 nM), Hck (IC50: 8 nM), mTOR (IC50: 10 nM), VEGFR2(IC50: 12 nM), Src (IC50: 14 nM) and Abl (IC50: 18 nM) , also inhibits DNA-PK (IC50: 60 nM).		Apoptosis , VEGFR , Bcr-Abl , PDGFR , Src , mTOR , Hck
T1812	KX1-004	KX1 004,KX1004	Src
	KX1-004, a potential protective drug for NIHL, is an effective small molecule inhibitor of Src-PTK.		Src
T2640	Rebastinib	DCC2036,DCC 2036,DCC-2036	Apoptosis , FLT , Bcr-Abl , Src
	DCC-2036 (Rebastinib (DCC-2036)) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and Abl1(T315I, IC50: 4 nM), also inhibits LYN, SRC, HCK, FGR, FLT3, KDR, and Tie-2, and low activity to c-Kit. Re...		Apoptosis , FLT , Bcr-Abl , Src
T7123	AMG-47a		VEGFR , p38 MAPK , JAK , Src
	AMG-47a is a potent inhibitor of Lck and T cell proliferation. AMG-47a could promote the degradation of the KRAS oncoprotein. AMG-47a selectively reduced the levels of EGFP-KRASG12V protein but did not affect EGFP protei...		VEGFR , p38 MAPK , JAK , Src
T1899	Pyridostatin	RR82,Pyridostatin Trifluoroacetate Salt	DNA/RNA Synthesis
	Pyridostatin (RR82) is a synthetic small-molecule stabilizer of G-quadruplexes, a secondary structure of DNA that usually exists in the end of the chromosome or the telomeres.		DNA/RNA Synthesis
T6196	PP1	EI 275,AGL 1872	Apoptosis , EGFR , Bcr-Abl , Src , c-Kit
	PP1 (AGL 1872), a specific and effective Src inhibitor, is with IC50 for Lck/Fyn is 5 nM/ 6 nM, respectively.		Apoptosis , EGFR , Bcr-Abl , Src , c-Kit
T1448	Dasatinib	BMS-354825	Apoptosis , Bcr-Abl , Src , c-Kit , Autophagy
	Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive. Dasatinib has antitumor activity and is used in the treatment of leukemia and ly...		Apoptosis , Bcr-Abl , Src , c-Kit , Autophagy
TQ0132	A 419259 trihydrochloride	RK 20449 trihydrochloride	Src
	A 419259 trihydrochloride (RK 20449 trihydrochloride) is an Src family kinases inhibitor (IC50s: 9 nM, 3 nM and 3 nM for Src, Lck and Lyn).		Src
T8719	SC99		Apoptosis , JAK , STAT
	SC99 is a selective inhibitor of JAK2-STAT3 activation. SC99 downregulates the expression of STAT3-modulated genes.SC99 inhibits platelet activation, aggregation and displays potent anti-myeloma, anti-thrombotic activiti...		Apoptosis , JAK , STAT
T15675	Tirbanibulin Mesylate	KX2-391 Mesylate,KX01 Mesylate	Microtubule Associated , Src
	Tirbanibulin Mesylate (KX01 Mesylate) is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).		Microtubule Associated , Src
T3935	1-Naphthyl PP1	1-NA-PP 1	Src
	1-Naphthyl PP1 (1-NA-PP 1) is a selective src inhibitor(v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively)		Src
T11826	LCH-7749944	GNF-PF-2356	Apoptosis , PAK
	LCH-7749944 (GNF-PF-2356) effectively suppresses the proliferation of human gastric cancer cells through downregulation of PAK4/c-Src/EGFR/cyclin D1 pathway and induces apoptosis. LCH-7749944 is a potent PAK4 inhibitor w...		Apoptosis , PAK
T2358	ENMD-2076		Apoptosis , VEGFR , FGFR , FLT , c-RET , PDGFR , Src , Aurora Kinase
	ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.
T6311	Bafetinib	NS-187,INNO-406	Bcr-Abl , Src , Autophagy
	Bafetinib (INNO-406) (INNO-406) is an effective and specific dual Bcr-Abl/Lyn inhibitor (IC50: 5.8/19 nM), and no inhibition of the phosphorylation of the T315I mutant and less effective to c-Kit and PDGFR.		Bcr-Abl , Src , Autophagy
T6896	Tolimidone	NSC 314335,MLR-1023,CP-26154	Src
	Tolimidone (NSC 314335) is a chemical compound which inhibits acid secretion in animal models and also acts as a bronchodilator in histamine-challenged animals.		Src
T2327	Pelitinib	EKB-569,WAY-EKB 569	EGFR , Raf , MEK , Src
	Pelitinib (EKB-569) (EKB-569) is an effective irreversible EGFR inhibitor (IC50: 38.5 nM).		EGFR , Raf , MEK , Src
T8976	PD-089828		EGFR , FGFR , PDGFR , Src
	PD 089828 is a competitive inhibitor of the receptor tyrosine kinases FGFR1, PDGFRβ, and EGFR (IC50s = 0.15, 1.76, and 5.47 µM, respectively) and a noncompetitive inhibitor of the nonreceptor tyrosine kinase c-Src (IC50 ...		EGFR , FGFR , PDGFR , Src

Compounds

Src Inhibitor 1

T3593

Synonym: Src Kinase Inhibitor 1,Src-l1

Target: Src

RR-src acetate

TP2289L

Synonym: RR-src acetate(81156-93-6 Free base)

Target: Others, Src

pp60 c-src (521-533) (phosphorylated) acetate

TP2137L

Synonym:

Target: Others

pp60 (v-SRC) Autophosphorylation Site, Phosphorylated

T39185

Synonym: pp60 (v-SRC) Autophosphorylation Site, Phosphorylated

Target:

Src Optimal Peptide Substrate

Synonym: KIN112,KIN001-112,Dual LCK/SRC inhibitor

RR-src

pp60 c-src (521-533) (phosphorylated)

TP2137

Synonym:

Target:

p60c-src substrate II

T76391

Synonym:

Target:

p60c-src substrate II, phosphorylated

Biotin-SRC-1 (676–700) TFA

T83752

Synonym: Biotin-Steroid Receptor Coactivator 1 (676-700)

Target: Bcr-Abl, Src, Autophagy

Target: IGF-1R, Bcr-Abl, Src, Aurora Kinase

PD173955

T3063

Synonym: PD-173955,PD 173955

Target: Apoptosis, Bcr-Abl, Src

TL02-59

T13186

Synonym:

Target: Apoptosis, Src, Hck

Saracatinib

T6078

Synonym: AZD0530

Target: EGFR, Src, BTK, Autophagy

Pyridostatin TFA

T4470

Synonym:

Target: DNA/RNA Synthesis

AD80

T4301

Synonym:

Target: Raf, c-RET, Src, S6 Kinase

Target: Syk, Src, p97

Tirbanibulin

T6345

Synonym: KX2-391,KX-01

Target: Microtubule Associated, Src

Hck-IN-1

T11538

Synonym:

Target: HIV Protease, Src, Hck

UM-164

T4597

Synonym: UM164,DAS-DFGO-II

Target: p38 MAPK, Src, Autophagy

CSF1R-IN-2

T13194

Synonym:

Target: c-Fms, c-Met/HGFR, Src

1-NM-PP1

T2153

Synonym: PP1 Analog II,1 nM-PP1

Target: Serine/threonin kinase, CDK, Src

SU6656

T6997

Synonym:

Target: FAK, Akt, Src

PP121

T2415

Synonym:

Target: Apoptosis, VEGFR, Bcr-Abl, PDGFR, Src, mTOR, Hck

KX1-004

T1812

Synonym: KX1 004,KX1004

Target: Src

Rebastinib

T2640

Synonym: DCC2036,DCC 2036,DCC-2036

Target: Apoptosis, FLT, Bcr-Abl, Src

AMG-47a

T7123

Synonym:

Target: VEGFR, p38 MAPK, JAK, Src

Pyridostatin

T1899

Synonym: RR82,Pyridostatin Trifluoroacetate Salt

Target: DNA/RNA Synthesis

PP1

T6196

Synonym: EI 275,AGL 1872

Target: Apoptosis, EGFR, Bcr-Abl, Src, c-Kit

Dasatinib

T1448

Synonym: BMS-354825

Target: Apoptosis, Bcr-Abl, Src, c-Kit, Autophagy

A 419259 trihydrochloride

TQ0132

Synonym: RK 20449 trihydrochloride

Target: Apoptosis, JAK, STAT

Tirbanibulin Mesylate

T15675

Synonym: KX2-391 Mesylate,KX01 Mesylate

Target: Microtubule Associated, Src

Target: Apoptosis, PAK

ENMD-2076

T2358

Synonym:

Target: Apoptosis, VEGFR, FGFR, FLT, c-RET, PDGFR, Src, Aurora Kinase

Bafetinib

T6311

Synonym: NS-187,INNO-406

Target: Bcr-Abl, Src, Autophagy

Tolimidone

T6896

Synonym: NSC 314335,MLR-1023,CP-26154

Target: Src

Pelitinib

T2327

Synonym: EKB-569,WAY-EKB 569

Target: EGFR, Raf, MEK, Src

PD-089828

T8976

Synonym:

Target: EGFR, FGFR, PDGFR, Src

カタログ番号	製品名	別名	ターゲット
T5S1982	Periplocin	Periplocoside	Apoptosis , Others
	1. Periplocin (Periplocoside) has anti-cancer effects on lung cancer cells, induces apoptosis and inhibits growth of cancer cells by the beta-catenin/Tcf signaling pathway. 2. Periplocin is used for treatment of rheumato...		Apoptosis , Others
TN1440	Beta-Hydroxyisovalerylshikonin		EGFR , Tyrosine Kinases , Prostaglandin Receptor , Src , AMPK , Fatty Acid Synthase
	Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor cell lines. Beta-Hydroxyisovalerylshikonin significantly de...
TN2269	Tetramethylcurcumin		Apoptosis , STAT
	Tetramethylcurcumin is a novel curcumin analog, is an effective inhibitors of STAT3 phosphorylation, DNA binding activity, and transactivation in vitro.it also inhibits colony formation in soft agar, cell invasion, and e...		Apoptosis , STAT
T3319	Scutellarein	4',5,6,7-Tetrahydroxyflavone,6-Hydroxyapigenin	SARS-CoV , Src , Autophagy
	Scutellarein (6-Hydroxyapigenin) reduces inflammatory responses by inhibiting Src kinase activity.		SARS-CoV , Src , Autophagy
T7345	7-Hydroxy-4H-chromen-4-one	7-hydroxy-4-benzopyrone,7-Hydroxy-4-chromone,7-Hydroxychromone	Src
	7-Hydroxy-4H-chromen-4-one (7-hydroxy-4-benzopyrone) is a Src kinase inhibitor (IC50 of <300 μM).		Src
TN1892	Lusianthridin		Others , c-Myc
	Lusianthridin is a natural product from Dendrobium venustum. Lusianthridin exhibits anti-migratory property at nontoxic concentrations. Lusianthridin enhances c-Myc degradation through the inhibition of Src-STAT3 signali...		Others , c-Myc
TQ0169	Inulicin	1-O-Acetylbritannilactone	FAK , NF-κB , COX , Src
	Inulicin (1-O-Acetylbritannilactone), an active compound isolated from Inula Britannica L, inhibits VEGF-mediated activation of Src and FAK.		FAK , NF-κB , COX , Src
T3S2390	Caftaric acid	trans-Caftaric acid	Others
	Caftaric acid (trans-Caftaric acid) is a natural product with antioxidant and anti-inflammatory properties, antimutagenicity, and an inhibitor of protein-protein interactions mediated by Src family kinases.		Others
TN1244	3'-Demethylnobiletin		LDL , NF-κB , Integrin , Lipoxygenase , DNA/RNA Synthesis
	3'-Demethylnobiletin has chemopreventive effects on colon carcinogenesis, it can significantly inhibit the growth of human colon cancer cells, cause cell-cycle arrest, induce apoptosis, and profoundly modulate signaling ...		LDL , NF-κB , Integrin , Lipoxygenase , DNA/RNA Synthesis
T5S0761	Nitidine chloride		Apoptosis , ERK , FAK , p38 MAPK , NF-κB , Topoisomerase , STAT , Parasite
	1. Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. 2. Nitidine chloride inhibits the proliferation of SMMC-7721 cells in vitro in a time- and dose-dependent manner and id...
T6427	Butein	2’,3,4,4’-tetrahydroxy Chalcone	Apoptosis , EGFR , Others , PDE , Autophagy
	Butein (2’,3,4,4’-tetrahydroxy Chalcone), a plant polyphenol, is isolated from Rhus verniciflua. It can inhibit the activation of protein tyrosine kinase, NF-κB and STAT3, and also can inhibit EGFR.		Apoptosis , EGFR , Others , PDE , Autophagy
T14055	5Z-7-Oxozeaenol	FR148083,L783279,LL-Z 1640-2	VEGFR , FLT , MEK , MAPK , PDGFR , Antibiotic , Src
	5Z-7-Oxozeaenol (FR148083) is a potent, irreversible and selective inhibitor of transforming growth factor (TGF)-β-activated kinase 1 with IC50 of 8.1 nM for TAK1 and low activity against MEK1 with IC50 of 411 nM, it is ...		VEGFR , FLT , MEK , MAPK , PDGFR , Antibiotic , Src

天然物製品

Periplocin

T5S1982

Synonym: Periplocoside

Target: Apoptosis, Others

Beta-Hydroxyisovalerylshikonin

TN1440

Synonym:

Target: EGFR, Tyrosine Kinases, Prostaglandin Receptor, Src, AMPK, Fatty Acid Synthase

Tetramethylcurcumin

TN2269

Synonym:

Target: Apoptosis, STAT

Scutellarein

T3319

Synonym: 4',5,6,7-Tetrahydroxyflavone,6-Hydroxyapigenin

Target: SARS-CoV, Src, Autophagy

7-Hydroxy-4H-chromen-4-one

T7345

Synonym: 7-hydroxy-4-benzopyrone,7-Hydroxy-4-chromone,7-Hydroxychromone

Target: Others, c-Myc

Inulicin

TQ0169

Synonym: 1-O-Acetylbritannilactone

Target: FAK, NF-κB, COX, Src

Caftaric acid

T3S2390

Synonym: trans-Caftaric acid

Target: LDL, NF-κB, Integrin, Lipoxygenase, DNA/RNA Synthesis

Nitidine chloride

T5S0761

Synonym:

Target: Apoptosis, ERK, FAK, p38 MAPK, NF-κB, Topoisomerase, STAT, Parasite

Butein

T6427

Synonym: 2’,3,4,4’-tetrahydroxy Chalcone

Target: Apoptosis, EGFR, Others, PDE, Autophagy

5Z-7-Oxozeaenol

T14055

Synonym: FR148083,L783279,LL-Z 1640-2

Target: VEGFR, FLT, MEK, MAPK, PDGFR, Antibiotic, Src

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-04384	Src Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Src Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 87.7 kDa and the accession number is P12931-1.
TMPY-04434	Src Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus Insect Cells
	Src Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 87.7 kDa and the accession number is NP_001020566.111.
TMPH-01977	Src Protein, Human, Recombinant (His)	Human	E. coli
	Src Protein, Human, Recombinant (His) is expressed in E. coli.
TMPY-04383	CSK Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	CSK Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 77 kDa and the accession number is P41240.
TMPY-04444	CSK Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus Insect Cells
	CSK Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 78.5 kDa and the accession number is P41241.
TMPY-04760	CSK Protein, Mouse, Recombinant	Mouse	Baculovirus Insect Cells
	CSK Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 50.9 kDa and the accession number is P41241.
TMPY-04388	BLK Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	Tyrosine-protein kinase Blk, also known as B lymphocyte kinase, p55-Blk and BLK, is a member of theprotein kinase superfamily, Tyr protein kinase family and SRC subfamily. BLK / p55-Blk is expressed in lymphatic organ...
TMPY-04391	Lyn Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	Tyrosine-protein kinase Lyn is a member of the Src family of protein tyrosine kinases, which is mainly expressed in hematopoietic cells, in neural tissues liver, and adipose tissue. Tyrosine-protein kinase Lyn has many f...
TMPY-04411	YES1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Proto-oncogene tyrosine-protein kinase Yes, also known as Proto-oncogene c-Yes, p61-Yes and YES1, is a cytoplasm protein that belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. YES1 /...
TMPY-02511	PTP alpha/PTPRA Protein, Human, Recombinant (aa 174-793, His & GST)	Human	Baculovirus Insect Cells
	PTPRA is reported to be involved in cancer development and progression through activating the Src family kinase (SFK) signaling pathways. The higher PTPRA level was associated with worse prognosis of SCC patients and PTP...
TMPH-02278	PTPN5 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors. PTPN5 Protein, Human, Recombinant (His & SUMO) i...
TMPJ-00712	MPZL1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Myelin protein zero-like protein 1(MPZL1) is encoded by the MPZL1 gene, which is a single-pass type I membrane protein. It is widely expressed with highest levels in heart, placenta, kidney and pancreas. As cell surface ...
TMPH-00376	IL-8/CXCL8 Protein, Chicken, Recombinant	Chicken	E. coli
	May be an autocrine factor that promotes the growth of fibroblasts and is involved in the neoplastic transformation of fibroblasts by v-Src. Chemotactic for peripheral blood mononuclear cells as well as for heterophils. ...
TMPH-00375	IL-8/CXCL8 Protein, Chicken, Recombinant (His)	Chicken	E. coli
	May be an autocrine factor that promotes the growth of fibroblasts and is involved in the neoplastic transformation of fibroblasts by v-Src. Chemotactic for peripheral blood mononuclear cells as well as for heterophils. ...
TMPH-01581	KRT1 Protein, Human, Recombinant (His)	Human	E. coli
	May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/H...
TMPY-02761	Rack1 Protein, Human, Recombinant (His & MBP)	Human	E. coli
	The scaffolding protein, Rack1, is a seven-WD-domain-containing protein that has been implicated in binding to integrin beta subunit cytoplasmic domains and to members of two kinase families (src and protein kinase C, PK...
TMPH-01428	TRAP1 Protein, Human, Recombinant (GST)	Human	E. coli
	Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to ...
TMPY-03510	Cbl-c Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	CBL proteins, such as Cbl-c, are phosphorylated upon activation of a variety of receptors that signal via protein tyrosine kinases. Through interactions with proteins containing SRC homology-2 (SH2) and SH3 domains, C...
TMPK-00423	CD45 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) com...
TMPK-00447	CD45 Protein, Human, Recombinant (aa 26-577, hFc)	Human	HEK293 Cells
	PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) com...
TMPK-00424	CD45 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) com...
TMPY-03296	SHP-1 Protein, Mouse, Recombinant (aa 207-597, His & GST)	Mouse	Baculovirus Insect Cells
	PTPN6 is an enzyme that belongs to the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and onco...
TMPJ-00396	SEMA4D Protein, Human, Recombinant (aa 22-734, His)	Human	HEK293 Cells
	Semaphorin-4D is also known as A8,BB18, GR3, CD100. Semaphorin-4D belongs to the semaphorin family containing 1 Ig-like C2-type domain, 1 PSI domain and 1 Sema domain. It is the cell surface receptor for PLXN1B and PLXNB...
TMPK-00457	HGFR/c-Met Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene.The protein possesses tyrosine kinase activity. The primary single chain ...
TMPK-00499	HGFR/c-Met Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene.The protein possesses tyrosine kinase activity. The primary single chain ...
TMPH-01297	DDR1 Protein, Human, Recombinant (aa 21-417, His)	Human	HEK293 Cells
	Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival ...
TMPJ-00326	CD122/IL2RB Protein, Human, Recombinant (aa 27-239, His & Avi), Biotinylated	Human	HEK293 Cells
	Human IL-2RB, also known asinterleukin-2 receptor subunit beta,is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 recepto...
TMPY-02191	BLNK Protein, Human, Recombinant (His)	Human	HEK293 Cells
	B-cell linker protein, also known as B-cell adapter containing a SH2 domain protein, B-cell adapter containing a Src homology 2 domain protein, Cytoplasmic adapter protein, Src homology 2 domain-containing leukocyte p...
TMPJ-00329	CD19 Protein, Rhesus macaque, Recombinant (hFc)	Rhesus	HEK293 Cells
	CD19 is a single-pass type I membrane protein containing 2 Ig-like C2-type (immunoglobulin-like) domains. CD19 is expressed on follicular dendritic cells and B cells. In fact, it is present on B cells from earliest recog...
TMPJ-00534	HFcgR4 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Fcgr4, also known as CD16-2, is one of the receptors for Fc region of IgG which involve in immune responses. Fcgr4 mainly functions in cellular response to lipopolysaccharide, NK T cell proliferation, regulation of senso...
TMPJ-00155	Mucin-1/MUC1 Protein, Human, Recombinant (hFc&Avi), Biotinylated	Human	HEK293 Cells
	Mucin-1, is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also ...
TMPY-02440	SAP/SH2D1A Protein, Human, Recombinant (His)	Human	E. coli
	SH2domain-containing protein 1A (SH2D1A / SAP) is a 128 amino acid protein, containing a single Src homology 2 (SH2) domain, flanked by 5 amino acids at the N-terminus and 25 amino acids at the C-terminus. The absence of...
TMPJ-01137	MIA Protein, Human, Recombinant (His)	Human	E. coli
	Melanoma Inhibitory Activity Protein (MIA) is an autocrine growth regulatory protein secreted from chondrocytes and malignant melanoma cells, which was the first discovered member of a family of secreted cytokines termed...
TMPH-02549	FHIT Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Possesses dinucleoside triphosphate hydrolase activity. Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP. Can also hydrolyze P(1)-P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A), but has extremely ...
TMPY-01831	SLAMF8 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	The signaling lymphocyte activation molecule (SLAM) family includes homophilic and heterophilic receptors that modulate both adaptive and innate immune responses. These receptors share a common ectodomain organization: a...
TMPY-02032	FLRT1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	The three fibronectin leucine-rich repeat transmembrane (FLRT) proteins contain 10 leucine-rich repeats (LRR), a type III fibronectin (FN) domain, followed by the transmembrane region, and a short cytoplasmic tail. FLRT1...
TMPY-04084	ANGPTL1 Protein, Canine, Recombinant (hFc)	Canine	HEK293 Cells
	Angiopoietin-like protein 1 (ANGPTL1) has been reported to suppress migration and invasion in lung and breast cancer, acting as a novel tumor suppressor candidate. Downregulation of tumor suppressor signaling plays an im...
TMPJ-00395	SEMA4D Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	SEMA4D is a member of the semaphorin family,contains one Ig-like C2-type domain, one PSI domain and one Sema domain. SEMA4D is strongly expressed in lymphoid tissues, especially in the thymus, as well as in the nervous t...
TMPY-04455	PKC iota Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	Protein kinase C iota type, also known as Atypical protein kinase C-lambda/iota, aPKC-lambda/iota and PRKCI, is a cytoplasm, membrane and nucleus protein which belongs to the protein kinase superfamily, AGC Ser/Thr prote...

Src Protein, Human, Recombinant (His & GST)

TMPY-04384

Species: Human

Expression System: Baculovirus Insect Cells

Src Protein, Mouse, Recombinant (His & GST)

TMPY-04434

Species: Mouse

Expression System: Baculovirus Insect Cells

Src Protein, Human, Recombinant (His)

TMPH-01977

Species: Human

Expression System: E. coli

CSK Protein, Human, Recombinant (GST)

TMPY-04383

Species: Human

Expression System: Baculovirus Insect Cells

CSK Protein, Mouse, Recombinant (His & GST)

TMPY-04444

Species: Mouse

Expression System: Baculovirus Insect Cells

CSK Protein, Mouse, Recombinant

TMPY-04760

Species: Mouse

Expression System: Baculovirus Insect Cells

BLK Protein, Human, Recombinant (GST)

TMPY-04388

Species: Human

Expression System: Baculovirus Insect Cells

Lyn Protein, Human, Recombinant (GST)

TMPY-04391

Species: Human

Expression System: Baculovirus Insect Cells

YES1 Protein, Human, Recombinant (His & GST)

TMPY-04411

Species: Human

Expression System: Baculovirus Insect Cells

PTP alpha/PTPRA Protein, Human, Recombinant (aa 174-793, His & GST)

TMPY-02511

Species: Human

Expression System: Baculovirus Insect Cells

PTPN5 Protein, Human, Recombinant (His & SUMO)

TMPH-02278

Species: Human

Expression System: E. coli

MPZL1 Protein, Human, Recombinant (His)

TMPJ-00712

Species: Human

Expression System: HEK293 Cells

IL-8/CXCL8 Protein, Chicken, Recombinant

TMPH-00376

Species: Chicken

Expression System: E. coli

IL-8/CXCL8 Protein, Chicken, Recombinant (His)

TMPH-00375

Species: Chicken

Expression System: E. coli

KRT1 Protein, Human, Recombinant (His)

TMPH-01581

Species: Human

Expression System: E. coli

Rack1 Protein, Human, Recombinant (His & MBP)

TMPY-02761

Species: Human

Expression System: E. coli

TRAP1 Protein, Human, Recombinant (GST)

TMPH-01428

Species: Human

Expression System: E. coli

Cbl-c Protein, Human, Recombinant (His & GST)

TMPY-03510

Species: Human

Expression System: Baculovirus Insect Cells

CD45 Protein, Human, Recombinant (His & Avi)

TMPK-00423

Species: Human

Expression System: HEK293 Cells

CD45 Protein, Human, Recombinant (aa 26-577, hFc)

TMPK-00447

Species: Human

Expression System: HEK293 Cells

CD45 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00424

Species: Human

Expression System: HEK293 Cells

SHP-1 Protein, Mouse, Recombinant (aa 207-597, His & GST)

TMPY-03296

Species: Mouse

Expression System: Baculovirus Insect Cells

SEMA4D Protein, Human, Recombinant (aa 22-734, His)

TMPJ-00396

Species: Human

Expression System: HEK293 Cells

HGFR/c-Met Protein, Human, Recombinant (His & Avi)

TMPK-00457

Species: Human

Expression System: HEK293 Cells

HGFR/c-Met Protein, Cynomolgus, Recombinant (His)

TMPK-00499

Species: Cynomolgus

Expression System: HEK293 Cells

DDR1 Protein, Human, Recombinant (aa 21-417, His)

TMPH-01297

Species: Human

Expression System: HEK293 Cells

CD122/IL2RB Protein, Human, Recombinant (aa 27-239, His & Avi), Biotinylated

TMPJ-00326

Species: Human

Expression System: HEK293 Cells

BLNK Protein, Human, Recombinant (His)

TMPY-02191

Species: Human

Expression System: HEK293 Cells

CD19 Protein, Rhesus macaque, Recombinant (hFc)

TMPJ-00329

Species: Rhesus

Expression System: HEK293 Cells

hFcgR4 Protein, Mouse, Recombinant (His)

TMPJ-00534

Species: Mouse

Expression System: HEK293 Cells

Mucin-1/MUC1 Protein, Human, Recombinant (hFc&Avi), Biotinylated

TMPJ-00155

Species: Human

Expression System: HEK293 Cells

SAP/SH2D1A Protein, Human, Recombinant (His)

TMPY-02440

Species: Human

Expression System: E. coli

MIA Protein, Human, Recombinant (His)

TMPJ-01137

Species: Human

Expression System: E. coli

FHIT Protein, Mouse, Recombinant (His)

TMPH-02549

Species: Mouse

Expression System: E. coli

SLAMF8 Protein, Mouse, Recombinant (His)

TMPY-01831

Species: Mouse

Expression System: HEK293 Cells

FLRT1 Protein, Human, Recombinant (His)

TMPY-02032

Species: Human

Expression System: HEK293 Cells

ANGPTL1 Protein, Canine, Recombinant (hFc)

TMPY-04084

Species: Canine

Expression System: HEK293 Cells

SEMA4D Protein, Mouse, Recombinant (hFc)

TMPJ-00395

Species: Mouse

Expression System: HEK293 Cells

PKC iota Protein, Human, Recombinant (GST)

TMPY-04455

Species: Human

Expression System: Baculovirus Insect Cells

カタログ番号	製品名
L1610	FDA-Approved Kinase Inhibitor Library	263 compounds
	A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.
L1600	Kinase Inhibitor Library	2720 compounds
	A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;

ライブラリー

FDA-Approved Kinase Inhibitor Library

L1610

Compounds: 263

Kinase Inhibitor Library

L1600

Compounds: 2720