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Search Results for " STAT3 "

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天然化合物

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カタログ番号	製品名	別名	ターゲット
T28865	STAT3-IN-B9	STAT3 IN B9,B9	STAT
	STAT3-IN-B9 (B9) is an inhibitor of abnormal STAT3 activation and inhibits the proliferation of tumor cells including MDA-MB-468, MDA-MB-231, and DU145.		STAT
T13009	STAT3-IN-1		Apoptosis , STAT
	STAT3-IN-1 selective and orally active inhibitor of STAT3(in HT29 and MDA-MB 231 cells, with IC50 values of 1.82 μM and 2.14 μM , respectively), induces tumor apoptosis.		Apoptosis , STAT
T62491	STAT3-IN-13		STAT
	STAT3-IN-13 is a potent STAT3 inhibitor.STAT3-IN-13 has antiproliferative and anticancer activity and acts by binding to the structural domain of STAT3 SH2.STAT3-IN-13 inhibits the phosphorylation of STAT3 Y705, which in...		STAT
T6308	Stattic	STAT3 Inhibitor V	Apoptosis , STAT
	Stattic (STAT3 Inhibitor V) is a STAT3 inhibitor (IC50=5.1 μM) that selectively inhibits STAT3 activation, dimerization, and nuclear translocation. Stattic has antitumor activity and induces apoptosis.		Apoptosis , STAT
T13010	STAT3-IN-3		STAT
	STAT3-IN-3 is a potent and selective signal transducer inhibitor and transcription 3 (STAT3) activator.		STAT
T71550	STAT3-IN-8		STAT
	"STAT3-IN-8 (compound H172) is a potent inhibitor of STAT3 with potential applications in cancer research [1]."		STAT
T79662	STAT3-IN-20		STAT
	STAT3-IN-20 (Compound 40), with an IC50 of 0.65 μM, is a selective inhibitor targeting the SH2 domain of STAT3, thereby impeding its phosphorylation, nuclear translocation, and subsequent gene transcription. The compound...		STAT
T74545	STAT3 degrader-1
	STAT3 Degrader-1 (Compound 295) is a potent degrader of STAT3, utilized in anticancer research [1].
T73035	STAT3-IN-15
	STAT3-IN-15, a potent and orally active inhibitor targeting STAT3, effectively combats idiopathic pulmonary fibrosis (IPF) by hindering STAT3 phosphorylation. Additionally, it impedes TGF-β1-induced migration and deforma...
T61779	STAT3-IN-9
	STAT3-IN-9, a potent inhibitor of STAT3 activation at Tyr705, exhibits no impact on the phosphorylation of STAT1 at Tyr 701. Additionally, this compound efficiently induces apoptosis and cell cycle arrest specifically at...
T61030	STAT3-IN-11		Apoptosis , STAT
	STAT3-IN-11 is a selective STAT3 inhibitor with inhibitory effects on phosphorylation of the STAT3pTyr705 site and phosphorylation of Survivin.STAT3-IN-11 promotes apoptosis in cancer cells and is a candidate compound fo...		Apoptosis , STAT
T71351	STAT3-IN-A69
	STAT3-IN-A69 is an inhibitor targeting the DNA-binding domain of STAT3, suppressing tumor growth, metastasis and STAT3 target gene expression in vivo.
T60765	STAT3-IN-10
	STAT3-IN-10 (A11) is an inhibitor of STAT3 that directly binds to STAT3 SH2 domain, inhibits tumor cell growth and induces apoptosis in cancer cells (IC 50 = 5.18 μM) [1].
T62803	STAT3-IN-12
	STAT3-IN-12 is a potent inhibitor of STAT3 signalling and inhibits IL-6-induced activation of the JAK/STAT3 signalling pathway. STAT3-IN-12 inhibits the growth and migration of cancer cells, blocks the cell cycle and ind...
T73114	STAT3-IN-7
	STAT3-IN-7, an orally active aryl sulfonamido azetidine compound, serves as a STAT3 inhibitor with anticancer activities.
T78983	STAT3 degrader-2		STAT
	STAT3 Degrader-2 is a PROTAC-based compound that effectively reduces the total STAT3 protein levels, and is utilized in the research of cancer and various diseases [1].		STAT
T79609	STAT3-IN-18		JAK
	STAT3-IN-18 (compound SPP), a platinum (IV) complex featuring an axial ligand from sandalwood, suppresses the JAK2-STAT3 pathway in breast cancer (BC) cells and exhibits anti-proliferative properties. It promotes apoptos...		JAK
T72754	JAK2/STAT3-IN-1
	JAK2/STAT3-IN-1 -10a) is a potent inhibitor of GP130, exhibiting an IC50 value of 3.04 µM and demonstrating anti-tumor activity.
T75099	PROTAC STAT3 degrader-2
	PROTAC STAT3 degrader-2 is a selective and efficacious PROTAC degrader of STAT3 protein with a DC 50 of 3.54 μM in Molm-16 Cell. PROTAC STAT3 degrader-2 has the potential for cancer research [1] .
T64629	Phospho-Stat3 (Tyr705) Antibody #9131R
	Phospho-Stat3 (Tyr705) Antibody #9131R is a useful organic compound for research related to life sciences and the catalog number is T64629.
T64573	Stat3 (124H6) Mouse mAb #9139M
	Stat3 (124H6) Mouse mAb #9139M is a useful organic compound for research related to life sciences and the catalog number is T64573.
T62317	α7 nAchR-JAK2-STAT3 agonist 1
	α7 nAchR-JAK2-STAT3 agonist 1 is a potent inhibitor of the α7 nAchR-JAK2-STAT3 pathway that acts on nitric oxide (NO) (IC50: 0.32 μM). α7 nAchR-JAK2-STAT3 agonist 1 has been shown to have a positive effect on iNOS, IL-1β...
T26936	C188	Cpd188,STAT3-IN-C188,Cpd-188,C 188,C-188
	C188 is a cell-permeable naphthol compound and a STAT3 inhibitor. C188 inhibits IL-6-stimulated STAT3 Tyr705 phosphorylation and nuclear translocation in HepG2 cells by targeting STAT3 SH2 domain peptide-binding pocket, ...
T71548	JH-I-25
	JH-I-25 is an IRAK1 kinase inhibitor.
T71350	Cinanserin
	Cinanserin is a serotonin 5-HT2 antagonist.
T8478	SC-43		Apoptosis , Phosphatase , STAT
	SC-43 is a potent and orally active agonist of SHP-1 (PTPN6). SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis, and with anti-fibrotic and anticancer effects.		Apoptosis , Phosphatase , STAT
T8476	RSVA405	RSVA 405	AMPK , STAT , Autophagy
	RSVA405 is an AMPK activator (EC50 = 1 μM), and is STAT3 inhibitor		AMPK , STAT , Autophagy
T6761	Ossirene	AS101	IL Receptor , Caspase , Interleukin
	Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.		IL Receptor , Caspase , Interleukin
T22424	1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea		Apoptosis , STAT
	SC-1 is a a derivative of the multiple tyrosine kinase inhibitor sorafenib. SC-1 potently inhibits the phosphorylation of STAT3 by blocking STAT3 phosphorylation and activation, and induces apoptosis in hepatocellular ca...		Apoptosis , STAT
T9195	SHR0302	ARQ252	Apoptosis , JAK
	SHR0302 (ARQ252) is a JAK inhibitor that binds JAK1 with stronger affinity than others (Selectivity for JAK1 is more than 10 times for JAK2, 77 times for JAK3, 420 times for Tyk2).		Apoptosis , JAK
T8742	G5-7	JAK2 inhibitor G5-7	Apoptosis , JAK
	JAK2 inhibitor G5-7 (JAK2 inhibitor G5-7) is an orally active JAK2 inhibitor, selectively inhibits JAK2–mediated phosphorylation and activation of EGFR (Tyr1068) and STAT3 by binding to JAK2. G5-7 has the potential for g...		Apoptosis , JAK
T13416	ZX-29		ALK
	ZX-29 is a potent and selective inhibitor of ALK(IC50 of 2.1 nM, 1.3 nM and 3.9 nM for ALK, ALK L1196M and ALK G1202R mutations, respectively), and also induces protective autophagy and has antitumor effect.		ALK
T9945	MNK8	3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione	STAT
	MNK8 (3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione) is a potent STAT3 inhibitor that reduces the ability of STAT3 to bind to DNA and also has a good growth inhibition effect on liver cancer cells [1].		STAT
T2544	Bazedoxifene acetate	WAY-TES 424,TSE 424,WAY-140424	Estrogen Receptor/ERR , Estrogen/progestogen Receptor
	Bazedoxifene acetate (WAY-TES 424) is a novel selective estrogen receptor modulator (SERM).		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
T6404	Bazedoxifene hydrochloride	Bazedoxifene HCl,TSE-424	Estrogen Receptor/ERR , Estrogen/progestogen Receptor
	Bazedoxifene hydrochloride (TSE-424) is a novel, non-steroidal, indole-based estrogen receptor modulator (SERM) binding to both ERα and ERβ with IC50 of 23 nM and 89 nM, respectively.		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
TP2222L	APTSTAT3-9R acetate		STAT
			STAT
TP2222	APTSTAT3-9R		Others
	APTSTAT3-9R-9R is a STAT3 inhibitor (Ki: 231 nmol/L). STAT3 has been reported to promote the proliferation, survival, metastasis, immune escape, as well as drug resistance of cancer cells, making it a promising target fo...		Others
T3708	BP-1-102		STAT
	BP-1-102 is an orally active, effective and specific STAT3 inhibitor. BP-1-102 binds Stat3 (Kd: 504 nM), then blocks Stat3-phosphotyrosine (pTyr) peptide interactions and Stat3 activation (4-6.8 μM), and selectively inhi...		STAT
T35544	ML115		STAT
	ML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of 2.0 nM, and is inactive against the related STAT1 and NFκB anti-targets.		STAT
T2505	S3I-201	S3I 201,S3I201	STAT
	S3I-201 (S3I-201) is a selective Stat3 inhibitor (IC50: 86±33 μM) and low effect towards STAT1/5.		STAT
T4650	C188-9	TTI-101	Apoptosis , STAT
	C188-9 (TTI-101) is a Stat3 inhibitor with an IC50 of 4-7 μM.		Apoptosis , STAT
TQ0052	SH5-07		STAT
	SH5-07 is a hydroxamic acid-based Stat3 inhibitor (IC50: 3.9 μM).		STAT
T6669	SH-4-54		STAT
	SH-4-54 is a most potent, small molecule, nonphosphorylated STAT3 inhibitor.		STAT
T2156	WP1066		Apoptosis , JAK , STAT
	WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3. WP1066 has been used in trials studying the treatment of Melanoma, Bra...		Apoptosis , JAK , STAT
T8719	SC99		Apoptosis , JAK , STAT
	SC99 is a selective inhibitor of JAK2-STAT3 activation. SC99 downregulates the expression of STAT3-modulated genes.SC99 inhibits platelet activation, aggregation and displays potent anti-myeloma, anti-thrombotic activiti...		Apoptosis , JAK , STAT
T6537	HO-3867	HO3867	Apoptosis , STAT
	HO-3867, an analog of curcumin, is a sspecific STAT3 inhibitor.		Apoptosis , STAT
T27613	InS3-54-A26		STAT
	inS3-54-A26 is an inhibitor of the DNA-binding domain of STAT3. inS3-54-A26 suppresses tumor growth, metastasis and the gene expression of STAT3.		STAT
T60160	STX-0119		STAT
	STX-0119 is a selective, orally active STAT3 dimerization inhibitor. STX-0119 inhibits STAT3 transcription with an IC50 of 74 μM.		STAT
T3218	Napabucasin	BBI608	STAT
	Napabucasin (BBI608) is an orally available Stat3 and Y cell stemness inhibitor.		STAT
T8597	ML116		STAT
	ML116 is a potent and selective STAT3 inhibitor.		STAT

Compounds

STAT3-IN-B9

T28865

Synonym: STAT3 IN B9,B9

Target: Apoptosis, STAT

Synonym: STAT3 Inhibitor V

Target: Apoptosis, STAT

Target: Apoptosis, STAT

PROTAC STAT3 degrader-2

T75099

Synonym:

Target:

Phospho-Stat3 (Tyr705) Antibody #9131R

T64629

Synonym:

Target:

Stat3 (124H6) Mouse mAb #9139M

T64573

Synonym:

Target:

α7 nAchR-JAK2-STAT3 agonist 1

Synonym: Cpd188,STAT3-IN-C188,Cpd-188,C 188,C-188

Target: Apoptosis, Phosphatase, STAT

RSVA405

T8476

Synonym: RSVA 405

Target: AMPK, STAT, Autophagy

Ossirene

T6761

Synonym: AS101

Target: IL Receptor, Caspase, Interleukin

1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea

T22424

Synonym:

Target: Apoptosis, STAT

SHR0302

T9195

Synonym: ARQ252

Target: Apoptosis, JAK

G5-7

T8742

Synonym: JAK2 inhibitor G5-7

Target: Apoptosis, JAK

Synonym: 3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione

Target: STAT

Bazedoxifene acetate

T2544

Synonym: WAY-TES 424,TSE 424,WAY-140424

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

Bazedoxifene hydrochloride

T6404

Synonym: Bazedoxifene HCl,TSE-424

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

Synonym: S3I 201,S3I201

Target: Apoptosis, STAT

Target: Apoptosis, JAK, STAT

SC99

T8719

Synonym:

Target: Apoptosis, JAK, STAT

HO-3867

T6537

Synonym: HO3867

Target: Apoptosis, STAT

カタログ番号	製品名	別名	ターゲット
T73070	STAT3-IN-14
	STAT3-IN-14 is a STAT3 inhibitor and has STAT3 phosphorylation inhibitory activity. STAT3-IN-14 can directly bind to the hinge region of STAT3 .
TN6739	Angoline	6-Methoxyldihydrochelerythrine	IL Receptor , STAT
	Angoline (6-Methoxyldihydrochelerythrine) hydrochloride is a potent and selective IL6/STAT3 signaling pathway inhibitor(IC50 : 11.56 μM). It inhibits STAT3 phosphorylation and its target gene expression, and inhibits can...		IL Receptor , STAT
T5S1252	Prosapogenin A	Progenin III	Apoptosis , Others
	Prosapogenin A (Progenin III) has anticancer activity.		Apoptosis , Others
T6995	Ochromycinone	STA 21,STA21,STA-21	Antibacterial , STAT
	Ochromycinone (STA 21) is a selective STAT3 inhibitor.		Antibacterial , STAT
T5668	Triacetylresveratrol	Acetyl-trans-resveratrol	BCL , NF-κB , STAT
	Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity,it inhibits the phosphorylation of STAT3 and NFκB, down-regulates Mcl-1, and up-regulates Bim and Puma in pancreatic cancer cells.		BCL , NF-κB , STAT
T3138	Astaxanthin	β-Carotene-4,4'-dione,Ovoester,AstaXin,AstaREAL,trans-Astaxanthin	Reactive Oxygen Species , PPAR
	Astaxanthin (trans-Astaxanthin) is a keto-carotenoid in the terpenes class of chemical compounds. It is classified as a xanthophyll but it is a carotenoid with no vitamin A activity. It is present in most red-colored aqu...		Reactive Oxygen Species , PPAR
T2814	Cryptotanshinone	Cryptotanshinon,Tanshinone c	STAT , Autophagy
	Cryptotanshinone (Cryptotanshinon), a STAT3 inhibitor (IC50: 4.6 μM) in a cell-free assay, strongly inhibits phosphorylation of STAT3 Tyr705, with a little effect on STAT3 Ser727, but no inhibition for STAT1 nor STAT5.		STAT , Autophagy
T4672	Brevilin A		Apoptosis , Anti-infection , JAK , STAT , Autophagy
	Brevilin A is a sesquiterpene lactone isolated from Centipeda minima, inhibits janus kinase activity and blocks STAT3 signaling in cancer cells with anti-tumor activity. Brevilin A is a selective inhibitor of JAK-STAT si...		Apoptosis , Anti-infection , JAK , STAT , Autophagy
T4S0145	Corylifol A	Corylinin	hCE , STAT , UGT
	1. Corylifol A (Corylinin) displays cytotoxic activity against HepG2 and Hep3B hepatocellular carcinoma cell lines, with IC50 values of 4.6 and 13.5 ug/ml, respectively. 2. Corylifol A and Biochanin A can be the potentia...		hCE , STAT , UGT
T2S1975	Ponicidin	Rubescensine B	Apoptosis , JAK , STAT
	Ponicidin (Rubescensine B) is a diterpenoid derived from Rabdosia rubescens. Ponicidin exhibits immunoregulatory, anti-inflammatory, anti-viral, and anti-cancer activity. Ponicidin induces apoptosis of gastric carcinoma ...		Apoptosis , JAK , STAT
T40660	Kansuinine B		IL Receptor , SARS-CoV
	Kansuinine B inhibits Stat3 activation induced by IL-6. Kansuinine B exhibits anti-viral activity and could be used in COVID-19 research.		IL Receptor , SARS-CoV
TN1620	Eriocalyxin B		Apoptosis , cAMP , NF-κB , STAT
	Eriocalyxin B induces apoptosis and cell cycle arrest in pancreatic adenocarcinoma cells through caspase- and p53-dependent pathways, should be considered a candidate for pancreatic cancer treatment; it is a specific inh...		Apoptosis , cAMP , NF-κB , STAT
T2896	Alantolactone	helenin,Eupatal,Helenine,(+)-Alantolactone,Alant camphor,Inula camphor	Apoptosis , STAT , TGF-beta/Smad
	Alantolactone (Inula camphor)(Alant camphor), a sesquiterpene lactone, has potential activity against triple-negative breast Y MDA-MB-231 cells by suppressing the signal transducer and activator of transcription 3 (STAT3...		Apoptosis , STAT , TGF-beta/Smad
TN4379	Kansuinine A		IL Receptor , STAT , Interleukin
	Kansuinine A possesses analgesic props, it also shows NGF inducing activity.		IL Receptor , STAT , Interleukin
TQ0196	Cucurbitacin I	NSC-521777,JSI-124,Elatericin B	JAK , STAT
	Cucurbitacin I (JSI-124), a natural compound, is a selective inhibitor of JAK2/STAT3 with anti-cancer activity.		JAK , STAT
TN2346	Mogrol		ERK , AMPK , STAT
	Mogrol, a biometabolite of mogrosides, functions by inhibiting the ERK1/2 and STAT3 pathways, diminishing CREB activation, and activating AMPK signaling.		ERK , AMPK , STAT
TN1892	Lusianthridin		Others , c-Myc
	Lusianthridin is a natural product from Dendrobium venustum. Lusianthridin exhibits anti-migratory property at nontoxic concentrations. Lusianthridin enhances c-Myc degradation through the inhibition of Src-STAT3 signali...		Others , c-Myc
T3913	Saikosaponin D		Estrogen Receptor/ERR , NF-κB , Antibacterial , STAT
	Saikosaponin D is a novel SERCA inhibitor by inhibiting NF-κB and STAT3 signaling to protect against acetaminophen-induced hepatotoxicity.		Estrogen Receptor/ERR , NF-κB , Antibacterial , STAT
T5S1607	Morusin	Mulberrochromene	NF-κB , Antibacterial , STAT
	1. Morusin (Mulberrochromene) possesses antitumor effects of cell lines including HT-29, A549, MCF-7, and MDA-MB-231, through suppressing STAT3 and NFκB attenuation mediated apoptosis induction. 2. Morusin possesses anti...		NF-κB , Antibacterial , STAT
T2789	Scutellarin	Breviscapin,Breviscapinun,Breviscapine,Scutellarein-7-glucuronide	Akt , HIV Protease , STAT
	Scutellarin (Scutellarein-7-glucuronide), an active flavone isolated from Scutellaria baicalensis, can inhibit RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts, and down-regulate the STAT3/Girdin/Akt signal...		Akt , HIV Protease , STAT
TN2269	Tetramethylcurcumin		Apoptosis , STAT
	Tetramethylcurcumin is a novel curcumin analog, is an effective inhibitors of STAT3 phosphorylation, DNA binding activity, and transactivation in vitro.it also inhibits colony formation in soft agar, cell invasion, and e...		Apoptosis , STAT
T3S1775	Tectochrysin	NSC 80687,Techtochrysine,Techtochrysin	NF-κB , STAT
	1. Tectochrysin (Techtochrysine) has antioxidant effect. 2. Tectochrysin is promising inhibitors for the reversal of ABCG2-mediated drug transport. 3. Tectochrysin leads to apoptotic cell death in NSC-LC cells through ac...		NF-κB , STAT
T4S2126	Ginkgetin		Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy
	1. Ginkgetin has anti-influenza virus and anti-fungal activities. 2. Ginkgetin has anti-inflammatory activity, can down-regulates COX-2 induction in vivo against skin inflammatory responses. 3. Ginkgetin is a good STAT3 ...		Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy
T5S0168	Atractylenolide II	2-Atractylenolide,Asterolide	Apoptosis , ERK , p38 MAPK , Akt , STAT
	1. Atractylenolide II (2-Atractylenolide) has antimelanoma effect by inhibiting STAT3 signalling. 2. Atractylenolide II has cytotoxic/apoptotic effects may via p38 activation , ERK and Akt inactivation, p53 dependent.		Apoptosis , ERK , p38 MAPK , Akt , STAT
TJS1779	Protosappanin A	PTA	NADPH-oxidase , IL Receptor , IκB/IKK , TNF , NF-κB , TLR , ROS , COX , HIV Protease , JAK , NO Synthase , STAT
	Protosappanin A (PTA) has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IÎºB/NF-ÎºB inflammation signal pathway; it exerts anti-neuroinflammatory ...
TN1405	Arnicolide D		Akt , Caspase , PI3K , STAT , mTOR
	Arnicolide D is a sesquiterpene lactone. Arnicolide D isolates from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling pathway and inhibits the PI3K/AKT/mTOR and STAT3 signaling path...		Akt , Caspase , PI3K , STAT , mTOR
T6427	Butein	2’,3,4,4’-tetrahydroxy Chalcone	Apoptosis , EGFR , Others , PDE , Autophagy
	Butein (2’,3,4,4’-tetrahydroxy Chalcone), a plant polyphenol, is isolated from Rhus verniciflua. It can inhibit the activation of protein tyrosine kinase, NF-κB and STAT3, and also can inhibit EGFR.		Apoptosis , EGFR , Others , PDE , Autophagy
T5S0734	Desmethoxyyangonin	Desmethoxy yangonin,Demethoxyyangonin,5,6-Dehydrokavain	Others , Monoamine Oxidase
	1. Desmethoxyyangonin (5,6-Dehydrokavain) protects LPS or LPS/D-GalN-induced damages in cell or liver tissues mainly through de-regulating IKK/NFκB and Jak2/STAT3 signaling pathways. 2. The induction of CYP3A23 by dihydr...		Others , Monoamine Oxidase
T3398	Icaritin	Anhydroicaritin,Cycloicaritin	Apoptosis , JAK , STAT , Autophagy
	Icaritin (Anhydroicaritin) has hormone regulation activity and cardiovascular function improvement activity. Icaritin has anticancer activity, can induce S phase arrest and apoptosis, inhibit ENKL cell proliferation. Ica...		Apoptosis , JAK , STAT , Autophagy
T3404	Cucurbitacin B	Cuc B,DATISCACIN,Amarine	Apoptosis , PTEN , Integrin , Endogenous Metabolite , HIF , STAT , Autophagy
	Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells. It inhibited AKT signaling activation through up-regulation of PTEN. Cucurbitacin B is an effective inh...
T2867	Diosgenin	Nitogenin	STAT
	Diosgenin (Nitogenin) is a spirostan found in DIOSCOREA and other plants. It has favorable effects in the improvement of diabetes and regulation of lipid metabolism.		STAT
T3S1471	Cucurbitacin IIA	Dihydrocucurbitacin Q1,Hemslecin A,Curcurbitacin IIA	Apoptosis , Survivin
	1. Cucurbitacin IIA (Dihydrocucurbitacin Q1) can induce apoptosis and enhance autophagy , contributes to the anti-inflammatory activity of Cucurbitacin IIA against inflammation-related diseases. 2. Cucurbitacin IIA is a ...		Apoptosis , Survivin
T6S2246	Alisol B 23-acetate	Alisol B Acetate,Alisol B monoacetate,23-O-Acetylalisol B,23-Acetylalismol B	Others
	1. Alisol B 23-acetate (Alisol B Acetate) produces protective effect against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regulation of transporters and enzymes. 2. Alisol B 23-acetate produces promotiv...		Others
TN1567	Delphinidin chloride		Estrogen Receptor/ERR , VEGFR
	Delphinidin chloride, a natural plant pigment found in berries and red wine, is a precursor of certain anthocyanins. Delphinidin chloride induces the release of nitric oxide from the vascular endothelium, resulting in va...		Estrogen Receptor/ERR , VEGFR
T3805	Prim-O-glucosylcimifugin	Cimifugin beta-D-glucopyranoside,Cimifugin 7-glucoside	TNF , COX , JAK , NO Synthase
	Prim-O-glucosylcimifugin (Cimifugin 7-glucoside) can inhibit the proliferation of SMC(smooth muscle cell) stimulated by TNF-alpha, increase the proportion of G0/G1 phase.		TNF , COX , JAK , NO Synthase
T6S1373	Casticin	Quercetagetin 3,6,7,4'-Tetramethyl Ether,Vitexicarpin	STAT
	1. Casticin (Vitexicarpin) can significantly reduce vascular inflammation, through inhibition of ROS-NF-κB pathway in vascular endothelial cells. 2. Casticin may become a potential leading drug in the therapy of prostate...		STAT
T7033	Rosmanol		Antioxidant , COX
	Rosmanol has antioxidant activity, it can activate the antioxidant response element. Rosmanol has biphasic modulation of GABAA receptors, demonstrates CNS activity in mouse models of antinociception, antidepressant and a...		Antioxidant , COX
T6S2116	Ginkgolic acid C17:1		Phosphatase , PTEN
	1. Ginkgolic acid C17:1 can significantly inhibit enterohemorrhagic Escherichia coli O157:H7(EHEC) biofilm formation on the surfaces of polystyrene and glass, and on nylon membranes.		Phosphatase , PTEN
T6S0141	Corylin		Antibacterial , Antibiotic , STAT
	Corylin is a major bioactive compound isolated from Psoralea corylifolia L; it has the activity of antibiotic or anticancer.		Antibacterial , Antibiotic , STAT
TN1244	3'-Demethylnobiletin		LDL , NF-κB , Integrin , Lipoxygenase , DNA/RNA Synthesis
	3'-Demethylnobiletin has chemopreventive effects on colon carcinogenesis, it can significantly inhibit the growth of human colon cancer cells, cause cell-cycle arrest, induce apoptosis, and profoundly modulate signaling ...		LDL , NF-κB , Integrin , Lipoxygenase , DNA/RNA Synthesis
T6S1699	Shogaol	[6]-Shogaol,6-Shogaol	Lipoxygenase , Autophagy
	1. 6-Shogaol (6-Shogaol) has antipyretic and analgesic effects in addition to inhibitory effect on lipoxygenase activity. 2. 6-shogaol has anti-inflammatory property, reduces the inflammatory response and protected the f...		Lipoxygenase , Autophagy
T5S0761	Nitidine chloride		Apoptosis , ERK , FAK , p38 MAPK , NF-κB , Topoisomerase , STAT , Parasite
	1. Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. 2. Nitidine chloride inhibits the proliferation of SMMC-7721 cells in vitro in a time- and dose-dependent manner and id...
T4S1469	Cucurbitacin IIb		Apoptosis , Others
	1. Cucurbitacin IIb is one of the major active compounds in Hemsleyadine tablets which have been used for clinical treatment of bacillary dysentery, enteritis and acute tonsilitis. 2. Cucurbitacin IIb exhibits its anti-i...		Apoptosis , Others
TN1674	Garcinone D		Reactive Oxygen Species , Nrf2 , STAT
	Garcinone D shows significant cytotoxicity against the CEM-SS cell line, with IC(50) value of 3.2 microg/ml; it exhibits dose-dependent enzyme-based microsomal aromatase inhibitory activity. Garcinone D inhibits p65 acti...		Reactive Oxygen Species , Nrf2 , STAT
T5S0167	Atractylenolide I		IL Receptor , TNF , TLR , JAK , STAT
	1. Atractylenolide-I has an anti-inflammatory effect by inhibiting TNF-α and IL-6 production; ameliorates sepsis syndrome, liver and kidney functions by reduction of pro-inflammatory cytokines and LPS. 2. Atractylenolide...		IL Receptor , TNF , TLR , JAK , STAT
T6S1141	Ganoderic acid A		Apoptosis , NF-κB , Endogenous Metabolite , Autophagy
	1. Ganoderic acid A exhibits antitumor activity, mediated through its inhibitory effect on nuclear transcription factor-kappaB and activator protein-1. 2. Ganoderic acid A can induce proliferation inhibition, apoptosis a...		Apoptosis , NF-κB , Endogenous Metabolite , Autophagy
T19885	Methyllucidone
	Methyllucidone is an inhibitor of STAT3 that acts by regulating the expression of the protein tyrosine phosphatase MEG2.
T75672	Angoline hydrochloride
	Angoline hydrochloride, a selective inhibitor of the IL6/STAT3 signaling pathway, demonstrates potent activity with an IC50 value of 11.56 μM. It effectively inhibits STAT3 phosphorylation and the expression of its targe...
T14330	Ascochlorin	Ilicicolin D	STAT
	Ascochlorin (Ilicicolin D), an isoprenoid antibiotic, primarily exerts its anti-tumor properties by inhibiting the STAT3 signaling pathway. It induces apoptosis and possesses anti-inflammatory activity[1][2][3].		STAT
T81690	Neocucurbitacin A		STAT
	Neocucurbitacin A (compound 7), a STAT3 inhibitor extracted from the pericarp of Aquilaria crassna, serves as a potential agent for anticancer research [1].		STAT
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天然物製品

Synonym: 6-Methoxyldihydrochelerythrine

Target: IL Receptor, STAT

Prosapogenin A

T5S1252

Synonym: Progenin III

Target: Apoptosis, Others

Ochromycinone

T6995

Synonym: STA 21,STA21,STA-21

Target: Antibacterial, STAT

Triacetylresveratrol

T5668

Synonym: Acetyl-trans-resveratrol

Target: BCL, NF-κB, STAT

Astaxanthin

T3138

Synonym: β-Carotene-4,4'-dione,Ovoester,AstaXin,AstaREAL,trans-Astaxanthin

Target: Reactive Oxygen Species, PPAR

Cryptotanshinone

T2814

Synonym: Cryptotanshinon,Tanshinone c

Target: STAT, Autophagy

Brevilin A

T4672

Synonym:

Target: Apoptosis, Anti-infection, JAK, STAT, Autophagy

Corylifol A

T4S0145

Synonym: Corylinin

Target: hCE, STAT, UGT

Ponicidin

T2S1975

Synonym: Rubescensine B

Target: Apoptosis, JAK, STAT

Kansuinine B

T40660

Synonym:

Target: IL Receptor, SARS-CoV

Eriocalyxin B

TN1620

Synonym:

Target: Apoptosis, cAMP, NF-κB, STAT

Alantolactone

T2896

Synonym: helenin,Eupatal,Helenine,(+)-Alantolactone,Alant camphor,Inula camphor

Target: Apoptosis, STAT, TGF-beta/Smad

Kansuinine A

TN4379

Synonym:

Target: IL Receptor, STAT, Interleukin

Cucurbitacin I

TQ0196

Synonym: NSC-521777,JSI-124,Elatericin B

Target: ERK, AMPK, STAT

Lusianthridin

TN1892

Synonym:

Target: Others, c-Myc

Saikosaponin D

T3913

Synonym:

Target: Estrogen Receptor/ERR, NF-κB, Antibacterial, STAT

Morusin

T5S1607

Synonym: Mulberrochromene

Target: NF-κB, Antibacterial, STAT

Scutellarin

T2789

Synonym: Breviscapin,Breviscapinun,Breviscapine,Scutellarein-7-glucuronide

Target: Akt, HIV Protease, STAT

Tetramethylcurcumin

TN2269

Synonym:

Target: Apoptosis, STAT

Tectochrysin

T3S1775

Synonym: NSC 80687,Techtochrysine,Techtochrysin

Target: NF-κB, STAT

Ginkgetin

T4S2126

Synonym:

Target: Apoptosis, Wnt/beta-catenin, COX, STAT, Autophagy

Atractylenolide II

T5S0168

Synonym: 2-Atractylenolide,Asterolide

Target: Apoptosis, ERK, p38 MAPK, Akt, STAT

Protosappanin A

TJS1779

Synonym: PTA

Target: NADPH-oxidase, IL Receptor, IκB/IKK, TNF, NF-κB, TLR, ROS, COX, HIV Protease, JAK, NO Synthase, STAT

Arnicolide D

TN1405

Synonym:

Target: Akt, Caspase, PI3K, STAT, mTOR

Butein

T6427

Synonym: 2’,3,4,4’-tetrahydroxy Chalcone

Target: Apoptosis, EGFR, Others, PDE, Autophagy

Desmethoxyyangonin

T5S0734

Synonym: Desmethoxy yangonin,Demethoxyyangonin,5,6-Dehydrokavain

Target: Others, Monoamine Oxidase

Icaritin

T3398

Synonym: Anhydroicaritin,Cycloicaritin

Target: Apoptosis, JAK, STAT, Autophagy

Cucurbitacin B

T3404

Synonym: Cuc B,DATISCACIN,Amarine

Target: Apoptosis, PTEN, Integrin, Endogenous Metabolite, HIF, STAT, Autophagy

Synonym: Dihydrocucurbitacin Q1,Hemslecin A,Curcurbitacin IIA

Target: Apoptosis, Survivin

Alisol B 23-acetate

T6S2246

Synonym: Alisol B Acetate,Alisol B monoacetate,23-O-Acetylalisol B,23-Acetylalismol B

Target: Estrogen Receptor/ERR, VEGFR

Prim-O-glucosylcimifugin

T3805

Synonym: Cimifugin beta-D-glucopyranoside,Cimifugin 7-glucoside

Target: TNF, COX, JAK, NO Synthase

Casticin

T6S1373

Synonym: Quercetagetin 3,6,7,4'-Tetramethyl Ether,Vitexicarpin

Target: Antioxidant, COX

Ginkgolic acid C17:1

T6S2116

Synonym:

Target: Phosphatase, PTEN

Corylin

T6S0141

Synonym:

Target: Antibacterial, Antibiotic, STAT

3'-Demethylnobiletin

TN1244

Synonym:

Target: LDL, NF-κB, Integrin, Lipoxygenase, DNA/RNA Synthesis

Shogaol

T6S1699

Synonym: [6]-Shogaol,6-Shogaol

Target: Lipoxygenase, Autophagy

Nitidine chloride

T5S0761

Synonym:

Target: Apoptosis, ERK, FAK, p38 MAPK, NF-κB, Topoisomerase, STAT, Parasite

Cucurbitacin IIb

T4S1469

Synonym:

Target: Apoptosis, Others

Garcinone D

TN1674

Synonym:

Target: Reactive Oxygen Species, Nrf2, STAT

Atractylenolide I

T5S0167

Synonym:

Target: IL Receptor, TNF, TLR, JAK, STAT

Ganoderic acid A

T6S1141

Synonym:

Target: Apoptosis, NF-κB, Endogenous Metabolite, Autophagy

Angoline hydrochloride

Synonym: Ilicicolin D

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-06624	STAT3 Protein, Human, Recombinant (His)	Human	E. coli
	STAT3 Protein, Human, Recombinant (His) is expressed in E. coli with His tag. The predicted molecular weight is 65.31 kDa. Accession number: P40763-1
TMPY-05493	LIFR Protein, Human, Recombinant (hFc)	Human	HEK293
	LIFR (leukemia inhibitory factor receptor) belongs to the family of cytokine receptors. LIFR forms a high-affinity receptor complex with gp130, which mediates the activity of LIF (leukemia inhibitory factor) and thus aff...
TMPY-00991	LIFR Protein, Human, Recombinant (His)	Human	HEK293
	LIFR (leukemia inhibitory factor receptor) belongs to the family of cytokine receptors. LIFR forms a high-affinity receptor complex with gp130, which mediates the activity of LIF (leukemia inhibitory factor) and thus aff...
TMPJ-00166	SCF Protein, Mouse, Recombinant	Mouse	E. coli
	Mouse stem cell factor (SCF), is the ligand for the receptor-type protein-tyrosine kinase KIT. It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gameto...
TMPY-04632	IL-15 Protein, Human, Recombinant	Human	E. coli
	The protein encoded by the IL15 gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common h...
TMPY-02959	IL-20 Protein, Human, Recombinant	Human	E. coli
	IL20/Interleukin-20 belongs to the IL-10 family. It is a cytokine structurally related to interleukin 10. IL20/Interleukin-20 can be detected in skin, trachea, and other tissues. It is produced by activated keratinocytes...
TMPJ-00778	HER2/ERBB2 Protein, Human, Recombinant (His)	Human	Human Cells
	Human epidermal growth factor receptor 2 (HER2) is a type of membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 plays a key role in development, cell proliferation and different...
TMPY-01170	IL-13RA1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha,...
TMPY-01258	IL-13RA1 Protein, Human, Recombinant (His)	Human	HEK293
	Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha,...
TMPY-00856	TCCR Protein, Human, Recombinant (hFc)	Human	HEK293
	The interleukin-27 receptor is a type I cytokine receptor for interleukin-27. It is a heterodimer composed of the interleukin 27 receptor, alpha subunit, and glycoprotein 130. WSX-1/IL-27R, a class I cytokine receptor th...
TMPY-01725	Leptin Receptor Protein, Human, Recombinant (His)	Human	HEK293
	Leptin Receptor or CD295 belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-spe...
TMPY-01870	IL-9 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Interleukin 9, also known as IL-9, is a cytokine (cell signaling molecule) belonging to the group of interleukins. IL-9 is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates...
TMPY-04799	IFNAR2 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	Interferon-alpha/beta receptor beta chain (IFNAR2) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus protei...
TMPY-05636	G-CSF Protein, Mouse, Recombinant	Mouse	HEK293
	Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins. It is produced by numerous cell types including immune and endothelial...
TMPY-04829	G-CSF Protein, Human, Recombinant	Human	HEK293
	Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins. It is produced by numerous cell types including immune and endothelial...
TMPY-03673	REG3B Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Expression of REG3B was sufficient to inhibit cytokine-induced activation of STAT3 in IECs. The human REG3beta protein, the functional counterpart of mouse REG3B, inhibited STAT3 activity in human 293T cells, and its exp...
TMPH-01630	LOXL3 Protein, Human, Recombinant (GST & His)	Human	E. coli
	Protein-lysine 6-oxidase that mediates the oxidation of peptidyl lysine residues to allysine in target proteins. Catalyzes the post-translational oxidative deamination of peptidyl lysine residues in precursors of elastin...
TMPH-03287	EPOR Protein, Rat, Recombinant (His & SUMO)	Rat	E. coli
	Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also ...
TMPH-00828	Erythropoietin Protein, Horse, Recombinant (His & SUMO)	Horse	E. coli
	Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activa...
TMPH-03111	Erythropoietin Protein, Pig, Recombinant (B2M & His)	Sus scrofa (Pig)	E. coli
	Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activa...
TMPH-02427	Erythropoietin Protein, Cynomolgus, Recombinant (His & SUMO)	Cynomolgus	E. coli
	Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activa...
TMPH-02531	ARID5A Protein, Mouse, Recombinant (His)	Mouse	Yeast
	DNA-binding protein that may regulate transcription and act as a repressor by binding to AT-rich stretches in the promoter region of target genes. May positively regulate chondrocyte-specific transcription such as of COL...
TMPH-02426	Erythropoietin Protein, Cynomolgus, Recombinant (His & Myc)	Cynomolgus	HEK293
	Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activa...
TMPH-00827	Erythropoietin Protein, Horse, Recombinant (hFc)	Horse	HEK293
	Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activa...
TMPH-03110	Erythropoietin Protein, Pig, Recombinant (His)	Sus scrofa (Pig)	Yeast
	Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activa...
TMPH-01777	TYK2 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Non-receptor kinase involved in various processes including cell growth, development, cell migration, innate and adaptive immunity. Plays both structural and catalytic roles in numerous cytokines and interferons signalin...
TMPH-01778	TYK2 Protein, Human, Recombinant (His)	Human	Baculovirus
	Non-receptor kinase involved in various processes including cell growth, development, cell migration, innate and adaptive immunity. Plays both structural and catalytic roles in numerous cytokines and interferons signalin...
TMPY-01187	Rac1 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	RAC1 is a GTPase that belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal re...
TMPK-00457	HGFR/c-Met Protein, Human, Recombinant (His & Avi)	Human	HEK293
	c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene.The protein possesses tyrosine kinase activity. The primary single chain ...
TMPY-06892	LIFR Protein, Rhesus, Recombinant (His)	Rhesus	HEK293
	LIFR (leukemia inhibitory factor receptor) belongs to the family of cytokine receptors. LIFR forms a high-affinity receptor complex with gp130, which mediates the activity of LIF (leukemia inhibitory factor) and thus aff...
TMPY-06010	LIFR Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	LIFR (leukemia inhibitory factor receptor) belongs to the family of cytokine receptors. LIFR forms a high-affinity receptor complex with gp130, which mediates the activity of LIF (leukemia inhibitory factor) and thus aff...
TMPY-03306	LIFR Protein, Rat, Recombinant (His)	Rat	HEK293
	LIFR (leukemia inhibitory factor receptor) belongs to the family of cytokine receptors. LIFR forms a high-affinity receptor complex with gp130, which mediates the activity of LIF (leukemia inhibitory factor) and thus aff...
TMPH-01559	IL-26 Protein, Human, Recombinant (His)	Human	Yeast
	May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expre...
TMPY-04817	Syntenin Protein, Human, Recombinant (His)	Human	E. coli
	Syntenin1/SDCBP (syndecan binding protein), also known as melanoma differentiation associated gene-9 (MDA-9), is a PDZ domain-containing molecule, which was initially identified as a key oncogene in melanoma. IL-6 promot...
TMPH-01560	IL-26 Protein, Human, Recombinant (His & Trx)	Human	E. coli
	May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expre...
TMPY-00487	PTPN9 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Protein tyrosine phosphatase non-receptor type 9 (PTPN9), also named PTP-MEG2, is an important member of the protein tyrosine phosphatase family that is involved in variety of human diseases.PTPN9 plays an important role...
TMPH-03265	CMKLR2 Protein, Rat, Recombinant (His)	Rat	in vitro E. coli expression system
	Receptor for chemoattractant adipokine chemerin/RARRES2 suggesting a role for this receptor in the regulation of inflammation and energy homesotasis. Signals mainly via beta-arrestin pathway. Binding of RARRES2 activates...
TMPY-01597	LIFR Protein, Mouse, Recombinant (His)	Mouse	HEK293
	LIFR (leukemia inhibitory factor receptor) belongs to the family of cytokine receptors. LIFR forms a high-affinity receptor complex with gp130, which mediates the activity of LIF (leukemia inhibitory factor) and thus aff...
TMPK-00025	IL-9 Protein, Human, Recombinant (hFc)	Human	HEK293
	IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pl...
TMPK-01071	IL-22RA1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Interleukin (IL)-22 is a member of the IL-10 family of cytokines and represents an important effector molecule of activated Th22, Th1, and Th17 cells, as well as Tc-cell subsets, gammadelta T cells, natural killer (NK), ...
TMPK-00499	HGFR/c-Met Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene.The protein possesses tyrosine kinase activity. The primary single chain ...
TMPK-00568	IL-9 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pl...
TMPK-01105	IL-22RA1 Protein, Human, Recombinant (hFc)	Human	HEK293
	Interleukin (IL)-22 is a member of the IL-10 family of cytokines and represents an important effector molecule of activated Th22, Th1, and Th17 cells, as well as Tc-cell subsets, gammadelta T cells, natural killer (NK), ...
TMPK-00026	IL-9 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pl...
TMPY-04084	ANGPTL1 Protein, Canine, Recombinant (hFc)	Canine	HEK293
	Angiopoietin-like protein 1 (ANGPTL1) has been reported to suppress migration and invasion in lung and breast cancer, acting as a novel tumor suppressor candidate. Downregulation of tumor suppressor signaling plays an im...
TMPJ-00080	IL-11 Protein, Human, Recombinant（P. pastoris）	Human	P. pastoris
	Interleukin 11 (IL-11) is a member of a family of human growth factors that includes human growth hormone, granulocyte colony-stimulating factor, and other growth factors. IL-11 is a thrombopoietic growth factor that dir...
TMPY-03500	ARL2BP Protein, Human, Recombinant (His)	Human	E. coli
	ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. ARL2BP binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activ...
TMPJ-00894	SCF Protein, Rat, Recombinant (His)	Rat	E. coli
	Stem cell factor (SCF), is the ligand for the receptor-type protein-tyrosine kinase KIT. It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesi...
TMPY-03476	IL-20 Protein, Rat, Recombinant	Rat	E. coli
	IL20/Interleukin-20 belongs to the IL-10 family. It is a cytokine structurally related to interleukin 10. IL20/Interleukin-20 can be detected in skin, trachea, and other tissues. It is produced by activated keratinocytes...
TMPJ-00776	HER2/ERBB2 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	Human Cells
	Human epidermal growth factor receptor 2 (HER2) is a type of membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 plays a key role in development, cell proliferation and different...
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STAT3 Protein, Human, Recombinant (His)

TMPY-06624

Species: Human

Expression System: E. coli

LIFR Protein, Human, Recombinant (hFc)

TMPY-05493

Species: Human

Expression System: HEK293

LIFR Protein, Human, Recombinant (His)

TMPY-00991

Species: Human

Expression System: HEK293

SCF Protein, Mouse, Recombinant

TMPJ-00166

Species: Mouse

Expression System: E. coli

IL-15 Protein, Human, Recombinant

TMPY-04632

Species: Human

Expression System: E. coli

IL-20 Protein, Human, Recombinant

TMPY-02959

Species: Human

Expression System: E. coli

HER2/ERBB2 Protein, Human, Recombinant (His)

TMPJ-00778

Species: Human

Expression System: Human Cells

IL-13RA1 Protein, Mouse, Recombinant (His)

TMPY-01170

Species: Mouse

Expression System: HEK293

IL-13RA1 Protein, Human, Recombinant (His)

TMPY-01258

Species: Human

Expression System: HEK293

TCCR Protein, Human, Recombinant (hFc)

TMPY-00856

Species: Human

Expression System: HEK293

Leptin Receptor Protein, Human, Recombinant (His)

TMPY-01725

Species: Human

Expression System: HEK293

IL-9 Protein, Human, Recombinant (His)

TMPY-01870

Species: Human

Expression System: Baculovirus-Insect Cells

IFNAR2 Protein, Human, Recombinant (His), Biotinylated

TMPY-04799

Species: Human

Expression System: HEK293

G-CSF Protein, Mouse, Recombinant

TMPY-05636

Species: Mouse

Expression System: HEK293

G-CSF Protein, Human, Recombinant

TMPY-04829

Species: Human

Expression System: HEK293

REG3B Protein, Mouse, Recombinant (His)

TMPY-03673

Species: Mouse

Expression System: HEK293

LOXL3 Protein, Human, Recombinant (GST & His)

TMPH-01630

Species: Human

Expression System: E. coli

EPOR Protein, Rat, Recombinant (His & SUMO)

TMPH-03287

Species: Rat

Expression System: E. coli

Erythropoietin Protein, Horse, Recombinant (His & SUMO)

TMPH-00828

Species: Horse

Expression System: E. coli

Erythropoietin Protein, Pig, Recombinant (B2M & His)

TMPH-03111

Species: Sus scrofa (Pig)

Expression System: E. coli

Erythropoietin Protein, Cynomolgus, Recombinant (His & SUMO)

TMPH-02427

Species: Cynomolgus

Expression System: E. coli

ARID5A Protein, Mouse, Recombinant (His)

TMPH-02531

Species: Mouse

Expression System: Yeast

Erythropoietin Protein, Cynomolgus, Recombinant (His & Myc)

TMPH-02426

Species: Cynomolgus

Expression System: HEK293

Erythropoietin Protein, Horse, Recombinant (hFc)

TMPH-00827

Species: Horse

Expression System: HEK293

Erythropoietin Protein, Pig, Recombinant (His)

TMPH-03110

Species: Sus scrofa (Pig)

Expression System: Yeast

TYK2 Protein, Human, Recombinant (E. coli, His)

TMPH-01777

Species: Human

Expression System: E. coli

TYK2 Protein, Human, Recombinant (His)

TMPH-01778

Species: Human

Expression System: Baculovirus

Rac1 Protein, Human, Recombinant (GST)

TMPY-01187

Species: Human

Expression System: Baculovirus-Insect Cells

HGFR/c-Met Protein, Human, Recombinant (His & Avi)

TMPK-00457

Species: Human

Expression System: HEK293

LIFR Protein, Rhesus, Recombinant (His)

TMPY-06892

Species: Rhesus

Expression System: HEK293

LIFR Protein, Human, Recombinant (His), Biotinylated

TMPY-06010

Species: Human

Expression System: HEK293

LIFR Protein, Rat, Recombinant (His)

TMPY-03306

Species: Rat

Expression System: HEK293

IL-26 Protein, Human, Recombinant (His)

TMPH-01559

Species: Human

Expression System: Yeast

Syntenin Protein, Human, Recombinant (His)

TMPY-04817

Species: Human

Expression System: E. coli

IL-26 Protein, Human, Recombinant (His & Trx)

TMPH-01560

Species: Human

Expression System: E. coli

PTPN9 Protein, Human, Recombinant (His & GST)

TMPY-00487

Species: Human

Expression System: Baculovirus-Insect Cells

CMKLR2 Protein, Rat, Recombinant (His)

TMPH-03265

Species: Rat

Expression System: in vitro E. coli expression system

LIFR Protein, Mouse, Recombinant (His)

TMPY-01597

Species: Mouse

Expression System: HEK293

IL-9 Protein, Human, Recombinant (hFc)

TMPK-00025

Species: Human

Expression System: HEK293

IL-22RA1 Protein, Mouse, Recombinant (hFc)

TMPK-01071

Species: Mouse

Expression System: HEK293

HGFR/c-Met Protein, Cynomolgus, Recombinant (His)

TMPK-00499

Species: Cynomolgus

Expression System: HEK293

IL-9 Protein, Cynomolgus, Recombinant (His)

TMPK-00568

Species: Cynomolgus

Expression System: HEK293

IL-22RA1 Protein, Human, Recombinant (hFc)

TMPK-01105

Species: Human

Expression System: HEK293

IL-9 Protein, Mouse, Recombinant (hFc)

TMPK-00026

Species: Mouse

Expression System: HEK293

ANGPTL1 Protein, Canine, Recombinant (hFc)

TMPY-04084

Species: Canine

Expression System: HEK293

IL-11 Protein, Human, Recombinant（P. pastoris）

TMPJ-00080

Species: Human

Expression System: P. pastoris

ARL2BP Protein, Human, Recombinant (His)

TMPY-03500

Species: Human

Expression System: E. coli

SCF Protein, Rat, Recombinant (His)

TMPJ-00894

Species: Rat

Expression System: E. coli

IL-20 Protein, Rat, Recombinant

TMPY-03476

Species: Rat

Expression System: E. coli

HER2/ERBB2 Protein, Human, Recombinant (hFc & Avi), Biotinylated

TMPJ-00776

Species: Human

Expression System: Human Cells

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カタログ番号	製品名
L3700	JAK-STAT Compound Library		252 compounds
	A unique collection of 252 JAK/STAT signaling targeted compounds for high throughput and high content screening;

ライブラリー

JAK-STAT Compound Library

L3700

Compounds: 252