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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T1349 | 5-Fluorouridine | Others , DNA/RNA Synthesis | |
5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine. 5-fluorouridine is a solid. This compound belongs to the pyrimidine nucleosides and analogues. These are compound... | |||
T2096 | Framycetin sulfate | Neomycin Sulphate B,Framycetin sulphate | Antibacterial , Antibiotic |
Framycetin sulfate (Neomycin Sulphate B) belongs to aminoglycoside class of antibiotics that contain two or more aminosugars connected by glycosidic bonds. | |||
T14522 | Beaucage reagent | DNA/RNA Synthesis | |
Beaucage reagent, which is found to be effective in causing DNA cleavage. | |||
T35187 | XR 5944 | XR-5944,MLN-944,MLN944,XR5944,MLN 944 | |
XR 5944 is an effective DNA binder that stabilizes topoisomerase-dependent cleavage and has shown superior efficacy in a variety of mouse and human tumor models. | |||
T27864 | LX-2931 | LX 3305,LX2931,LX-3305,ACB20034,LX 2931,LX3305 | S1P Receptor |
LX-2931(LX-3305) is a sphingosine-1-phosphate cleavage enzyme (S1P) inhibitor for the treatment of rheumatoid arthritis. | |||
T11527L | H-Ser-His-OH acetate | Endogenous Metabolite | |
H-Ser-His-OH acetate is an endogenous metabolite hydrolysis cleavage activity. | |||
T30161 | EN3356 | AS N001,ASN-001 | P450 |
EN3356 is an orally available and selective inhibitor of steroidal 17-alpha-hydroxylase/C17,20 cleavage enzyme (CYP17A1 or CYP17), a non-steroidal cleavage enzyme-selective compound with potential anti-androgenic and ant... | |||
T67887 | BDCRB | ||
BDCRB inhibits herpesvirus DNA maturation. BDCRB causes the HCMV terminase to skip the normal cleavage site and to continue to package DNA until a second cleavage site is encountered 30 kb further along the concatemer. | |||
T77627 | Opevesostat | ODM208,ODM-208 | P450 |
Opevesostat (ODM-208) is an inhibitor of lyase (CYP11A1) (the enzyme cleavage cholesterol side chain). | |||
T20318 | Benzylideneaniline | N-Benzylideneaniline | Others |
Benzylideneaniline (N-Benzylideneaniline) is a potent inhibitor of xyloglucan-α,β-dioxygenase, a key enzyme in the oxidative cleavage of the central double bond of xyloglucan. | |||
TP2180L | Compstatin control peptide acetate | Complement System | |
Compstatin control peptide acetate is an inhibitor of complement protein C3 by binding and inhibiting the cleavage of complement C3. | |||
T1772 | MDK83190 | Apoptosis Activator 2 | Apoptosis , Caspase |
MDK83190 (Apoptosis Activator 2) is a potent apoptosis activator, induceing caspase-3 activation, PARP cleavage, and DNA fragmentation . | |||
TP1835L | Enterostatin, human, mouse, rat acetate | Endogenous Metabolite | |
Enterostatin, human, mouse, rat acetate is a pentapeptide mainly formed in the intestine by the cleavage of secreted pancreatic procolipase. | |||
T19522 | PNPG | 4-Nitrophenyl β-D-glucopyranoside | Others |
PNPG (4-Nitrophenyl β-D-glucopyranoside) is a chromogenic substrate for β-D-glucosidase that, upon enzymatic cleavage, yields a yellow solution. | |||
T2208 | Bacitracin Zinc | Bacitracin zinc salt,Zinc bacitracin | c-Met/HGFR , Antibacterial , Antibiotic |
Bacitracin Zinc is an antibiotic that interferes with the dephosphorylation of C55-isoprenyl pyrophosphate, interference for inhibition of cleavage of Tyr from Met-enkephalin(IC50=10 μM). | |||
TP1181 | Bradykinin (2-9) | Des-Arg1-bradykinin | Bradykinin Receptor |
Bradykinin (2-9) (Des-Arg1-bradykinin) is an amino-truncated peptide compound that is a metabolite of Bradykinin. It is formed by the cleavage action of Aminopeptidase P. | |||
T16037 | GLN-1062 | Others | |
Memogain is a pro-drug of galantamine. It is used for the treatment of Alzheimer’s disease. | |||
TP1545L1 | FFAGLDD amine salt | Others | |
FFAGLDD amine salt is MMP9 selective cleavage peptides, which used for cytosolic delivery of Doxorubi-cin (DOX) and achieve temporally and spatially controlled slow drug delivery and release. | |||
T73560 | I-138 | DUB | |
I-138 is an orally active and potent reversible inhibitor of USP1-UAF1.I-138 induces mono-ubiquitination of FANCD2 and PCNA and inhibits USP1 auto-cleavage in cells. | |||
T6336 | Amonafide | NSC308847,AS1413,Nafidimide,AS1413,Quinamed | Topoisomerase |
Amonafide (NSC-308847,AS1413)(AS1413) produces protein-associated DNA-strand breaks through a topoisomerase II-mediated reaction, but does not produce topoisomerase I-mediated DNA cleavage. | |||
TP1273 | FLAG peptide | Others | |
FLAG peptide is an eight amino acids peptide (Asp-Tyr-Lys-Asp-Asp-Asp-Asp-Lys) with an enterokinase-cleavage site used for the purification of recombinant proteins. | |||
T3521 | γ-Secretase-IN-1 | Compound E | Beta Amyloid , Gamma-secretase |
γ-Secretase-IN-1 is a potent γ-secretase inhibitor that displays partial antiproliferative activity on T-47D cells and inhibits β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage. | |||
T26326 | VU0285655-1 | VU-0285655,VU0285655,BML 280,VU 0285655,BML280,BML-280 | TNF , Phospholipase , Interleukin |
VU0285655-1(BML-280) is a potent and selective phospholipase D2 (PLD2) inhibitor that inhibits the proliferation of PLD2-deficient cells.VU0285655-1 has an inhibitory effect on high glucose-induced caspase-3 cleavage and... | |||
T22094 | JGB1741 | ILS-JGB-1741 | Sirtuin |
JGB1741 (ILS-JGB-1741) is a potent and selective inhibitor of SIRT1 with an IC50 of 15 μM. JGB1741 modulates Bax/Bcl2 ratio, cytochrome c release and PARP cleavage and increases the acetylated p53 levels leading to p53-m... | |||
T13410 | ZLDI-8 | Apoptosis , Phosphatase , Gamma-secretase , Immunology/Inflammation related | |
ZLDI-8 is an inhibitor of Notch activating/cleaving enzyme ADAM-17 and inhibits the cleavage of Notch protein. | |||
T77579 | JC2-11 | IL Receptor , Dehydrogenase , ROS , Caspase , NOD-like Receptor (NLR) , AIM2 | |
JC2-11 is an inhibitory compound for inflammation.JC2-11 inhibits the recruitment domain-containing proteins NLRC 4, atypical in melanoma 2 (AIM 2) and atypical (NC) inflammatory vesicles by disrupting reactive oxygen sp... | |||
T3633 | Crenigacestat | LY3039478 | Gamma-secretase |
Crenigacestat (LY3039478) is an orally bioavailable Notch inhibitor with an IC50 of ~1 nM in most of the tumor cell lines tested. Crenigacestat effectively inhibits mutant Notch receptor activity. In a xenograft tumor mo... | |||
TP1143L | Fibrinopeptide A, human acetate | Fibrinopeptide A, human acetate(25422-31-5 free base),Human fibrinopeptide A acetate | Others |
Fibrinopeptide A, human acetate (Human fibrinopeptide A acetate) is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A (FPA) is produced from the N-terminal Aα region of fibrinogen prote... | |||
T9266 | Fatostatin | Lipid , Fatty Acid Synthase | |
Fatostatin is a specific inhibitor of SREBP activation, it impairs the activation of SREBP-1 and SREBP-2. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs. | |||
T1699 | Resorufin galactopyranoside | Others | |
resorufin galactopyranoside is a fluorescent substrate for β-galactosidase.After cleavage by β-galactosidase, the fluorescent portion of resorufin is released and its fluorescence can be used to quantify β-galactosidase ... | |||
TP1341L | Polymyxin B nonapeptide acetate | Polymyxin B nonapeptide acetate(86408-36-8 free base) | Antibacterial , Antibiotic |
Polymyxin B nonapeptide acetate is a cationic cyclic peptide. Polyxin B nonapeptide is a derivative produced by enzymatic cleavage of polyxin B. Compared with polyxin B, polyxin B nonapeptide has low toxicity, lacks bact... | |||
TP1917L1 | Sar-[D-Phe8]-des-Arg9-Bradykinin acetate | Sar-[D-Phe8]-des-Arg9-Bradykinin acetate(126959-88-4 free base) | Bradykinin Receptor |
Sar-[D-Phe8]-des-Arg9-Bradykinin acetate is a potent and selective bradykinin B1 receptor agonist (EC50 = 9.02 nM in rabbit aorta) that is resistant to aminopeptidase, kininase I and II (ACE) and neutral endopeptidase cl... | |||
T31011 | Coralyne chloride | Topoisomerase | |
Coralyne chloride is a protoberberine with strong anticancer activity. It can be used to prepare Coralyne derivatives, a fluorescent DNA-based molecular rectifier built into DNA duplexes through site-specific insertion. ... | |||
T60130 | USP5-IN-1 | DUB | |
USP5-IN-1 (compound 64) is a potent deubiquitinase USP5 inhibitor, which binds to the USP5 ZnF-UBD with a KD of 2.8 μM and is selective over nine proteins containing structurally similar ZnF-UBD domains. USP5-IN-1 inhibi... | |||
T77124 | Osocimab | BAY 1213790 | FXR |
Osocimab (BAY 1213790) is a potent anti-FXIa antibody with a Ki value of 2.4 nM and an EC50 value of 0.2 nM.Osocimab may reduce thrombosis through FXI inhibition.Osocimab is often used as an XI factor inhibitor, has an i... | |||
T16500 | PF-3450074 | PF-74 | HIV Protease |
PF-3450074 (PF-74) acts at an early stage of HIV-1 infection inhibits viral replication by directly competing with the binding of CPSF6 (nuclear host factors cleavage and polyadenylation specific factor 6) and NUP153 (nu... | |||
T7037 | 7-Acetoxy-4-methylcoumarin | MU-Ac | Others |
7-Acetoxy-4-methylcoumarin is a fluorogenic substrate for carboxylesterase yielding a blue fluorescent solution upon cleavage. The compound has been used in aprotic media, a cell membrane environmental mimic, to study su... | |||
T6063 | LY-411575 | LY411575 | Apoptosis , Gamma-secretase |
LY-411575, a potent γ-secretase inhibitor, is with IC50 of 0.078 nM in the membrane and 0.082 nM in cell-based. It also suppresses Notch clevage with IC50 of 0.39 nM. | |||
T3226 | Paritaprevir | ABT-450,Veruprevir | HCV Protease |
Paritaprevir (ABT-450) is an orally bioavailable, synthetic acylsulfonamide inhibitor of the hepatitis C virus (HCV) protease complex comprised of non-structural protein 3 and 4A (NS3/NS4A), with potential activity again... | |||
T26240 | Surfen dihydrochloride | Aminokinuride dihydrochloride,Aminoquinuride dihydrochloride,NSC-12155,Aminokinuride 2HCl,Aminoquinuride 2HCl | FGFR , Antiviral , Antibiotic |
Surfen dihydrochloride (Aminoquinuride dihydrochloride) is a potent small molecule antagonist of heparin sulphate with antimicrobial and antiviral activity and inhibits anthrax lethal factor, coagulation factor X and let... | |||
T31032 | CP 80080 | CP80080,CP-80080,CP-80,080 | |
CP 80080 weakly enhances topoisomerase II-mediated DNA cleavage. | |||
T35662 | Cortistatin-29 (1-13) (rat) (trifluoroacetate salt) | ||
Cortistatin-29 (1-13) is a neuropeptide and cleavage product of cortistatin-29 , which is a cleavage product of procortistatin. Cortistatin-29 (1-13) corresponds to the first 13 amino acids of cortistatin-29. | |||
T33960 | Phaseolotoxin | Phaseolotoxin A | |
Phaseolotoxin is an exotoxin from Pseudomonas sp.; cleavage of C terminal alanine and homoarginine from phaseolotoxin leaves octicidine. | |||
T71031 | Deldeprevir Na | ||
Deldeprevir Na is an Antiviral Polyprotein cleavage inhibitor. HCV NS3/4A inhibitor. | |||
T15200 | Edotecarin | PF 804950,J 107088 | Topoisomerase |
T24210 | JNJ-40418677 | ||
JNJ-40418677 is a γ-secretase modulator that selectively blocks γ-site cleavage of the APP without affecting the processing of Notch. | |||
T37574 | 4-Nitrophenyl-N-acetyl-α-D-galactosaminide | ||
N-acetyl-D-galactosaminidase catalyzes the cleavage of N-acetylglucosamine (GlcNAc), the monomeric unit of the polymer chitin. 4-Nitrophenyl-N-acetyl-α-D-galactosaminide can be used as a chromogenic substrate for N-acety... | |||
T39765 | Mal-PEG1-Val-Cit-PAB-PNP | Mal-PEG1-Val-Cit-PAB-PNP | |
Mal-PEG1-Val-Cit-PAB-PNP is an ADC linker employed in the synthesis of ADCs, enabling cleavage. | |||
T70732 | APX2014 | ||
APX2014 is a novel potent and specific Ref-1 inhibitor, blocking in vitro cell proliferation and activating apoptosis via PARP cleavage. | |||
TP1210 | Bradykinin (1-7) | Bradykinin Fragment 1-7 | |
Bradykinin (1-7), an amino-truncated peptide derived from Bradykinin, is a metabolite formed through enzymatic cleavage by endopeptidase. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T17143 | Toyocamycin | Vengicide | Apoptosis , Others , IRE1 , Antibiotic , Antifungal |
Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM). Toyocamycin induces apoptosis. | |||
T11665 | Ionomycin calcium | SQ23377 calcium | Apoptosis , Calcium Channel , Antibacterial , Antibiotic , PKC |
T11589 | Hydroxycitric acid tripotassium hydrate | Potassium citrate monohydrate | ATP Citrate Lyase , HIF/HIF Prolyl-Hydroxylase , HIF |
Hydroxycitric acid tripotassium hydrate (Potassium citrate monohydrate) effectively inhibits stones formation and also inhibits HIF, and has antioxidation, anti-inflammation, and anti-tumor effects. Hydroxycitric acid tr... | |||
T0256 | Citric acid trilithium salt tetrahydrate | Lithium citrate tribasic tetrahydrate,Trilithium citrate tetrahydrate | Dehydrogenase , GSK-3 , HIF/HIF Prolyl-Hydroxylase , Antibacterial , GluR |
Citric acid trilithium salt tetrahydrate (Lithium citrate tribasic tetrahydrate) , the active component of Lithium, is a medicine used in the therapy of psychiatric disease. It has shown the effects of signaling pathways... | |||
T21498 | Phleomycin | DNA/RNA Synthesis , Antibacterial , Antibiotic | |
Phleomycin is one of the anticancer glycopeptide antibiotics which cause DNA cleavage. It is similar to Bleomycin which binds and intercalates DNA to damage the integrity of the double helix. | |||
TN1067 | Galloylpaeoniflorin | 6'-O-Galloyl paeoniflorin | NF-κB , Androgen Receptor , ROS |
Galloylpaeoniflorin (6'-O-Galloyl paeoniflorin) may be developed as a cytoprotector against ROS-mediated oxidative stress. Galloylpaeoniflorin is also an inhibtior of NF-κB and DNA cleavage. | |||
TN1414 | Aurantio-obtusin β-D-glucoside | Aurantio-obtusin beta-D-glucoside | Others |
Aurantio-obtusin β-D-glucoside (Aurantio-obtusin beta-D-glucoside) is a natural product originated from the enzymatic cleavage of its glucoside glucoaurantio-obtusin. | |||
T19357 | Hyaluronidase | Hyaluronate 4-glycanohydrolase,Hyaluronoglucosaminidase | Others |
Hyaluronidase (Hyaluronate 4-glycanohydrolase), a naturally occurring enzyme, depolymerizes hyaluronic acid through glycosidic bond cleavage and is utilized in ophthalmic surgery. | |||
T2947 | Indole-3-carbinol | I3C,3-Indolemethanol,Indole-3-Methanol | E1/E2/E3 Enzyme , NF-κB , Aryl Hydrocarbon Receptor , Endogenous Metabolite , p53 |
Indole-3-carbinol (I3C), a naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, inhibits NF-κB and IκBα kinase activation. | |||
T5782 | Bevirimat | YK FH312,MPC-4326,PA-457 | HIV Protease |
Bevirimat (PA-457) is a first-in-class inhibitor of HIV-1 maturation, blocking the cleavage of the Gag capsid (CA) precursor, CA-SPI, to mature CA protein during virion maturation. | |||
TN6908 | Polyporusterone A | (1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R,5S)-2,3-dihydroxy-5,6-dimethylheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one | |
Polyporusterone A is a triterpene carboxylic acid derived from the substrates of P. umbellatus.Polyporusterone A inhibits free radical-induced erythrocyte cleavage (hemolysis), and can be used in studies of hair regenera... | |||
T5254 | Glycodeoxycholate Sodium | Sodium glycyldeoxycholate,Sodium glycodeoxycholate,Glycodeoxycholic acid sodium salt | Others , Endogenous Metabolite |
Glycodeoxycholate Sodium (Glycodeoxycholic acid sodium salt) induces Apoptosis in hepatocytes by a mechanism associated with DNA cleavage by endonucleases. It is a secondary bile acid produced by the action of enzymes ex... | |||
T2721 | Digitonin | Others | |
Digitonin is a natural product of the glycoside family and is a detergent. Digitonin has antitumor activity, binds to cholesterol molecules to increase the permeability of cell membranes, and is active in the cleavage of... | |||
T12045 | (-)-Hydroxycitric acid lactone | Garcinia lactone | ATP Citrate Lyase |
(-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent.(-)-Hydroxycitric acid lactone was a potent inhibitor of ATP citrate lyase, which catalyzes the extramitochondrial cleavage of citrate to oxaloac... | |||
T4717 | 25-Hydroxycholesterol | Others , Endogenous Metabolite , HMG-CoA Reductase | |
25-Hydroxycholesterol is a steroid derivative that suppresses the cleavage of sterol regulatory element binding proteins (SREBPs). It inhibits HMG-CoA reductase and so it also plays a significant role in the in vivo regu... | |||
T0200 | α-Lipoic Acid | Thioctic acid,DL-α-Lipoic acid,(±)-α-Lipoic acid | Apoptosis , NF-κB , HIV Protease , Mitochondrial Metabolism , Endogenous Metabolite |
α-Lipoic Acid (DL-α-Lipoic acid) an octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme ... | |||
T6S2391 | L-Chicoric Acid | (-)-Chicoric acid,trans-Caffeoyltartaric acid,Chicoric acid,dicaffeoyltartaric acid | Others , HIV Protease |
L-Chicoric Acid (trans-Caffeoyltartaric acid) has been shown to inhibit hyaluronidase and HIV-1 integrase, and to possess phagoeytosis stimulatory activity in vitro and in vivo and antiviral acitivy. L-Chicoric acid may ... | |||
TN1037 | Groenlandicine | Topoisomerase | |
Groenlandicine is a protoberberine alkaloid from Coptidis Rhizoma. Groenlandicine exhibits moderate inhibitory effect with IC50 value of 154.2 μM for human recombinant aldose reductase (HRAR). Groenlandicine selectively ... | |||
TN1880 | Lucidenic acid B | Lucidenicacid B | Apoptosis , Caspase |
Lucidenic acid B (Lucidenicacid B), a natural compound extracted from Ganoderma lucidum, induces activation of caspase-9 and caspase-3 and cleavage of PARP, which can induce apoptosis in human leukemia cells through mito... | |||
T9113 | Myristicin | Myristicine | IL Receptor , Anti-infection , BCL , P450 , PARP , 5-HT Receptor , Caspase , GABA Receptor , NO Synthase |
Myristicin (Myristicine) is a natural product found in spices and umbelliferous plants. Myristicin has anti-cholinergic, Antibacterial, and hepatoprotective effects, it also has anti-inflammatory properties related with ... | |||
T4757 | L-Homoserine | (S)-(-)-2-AMINO-4-HYDROXYBUTYRIC ACID | Others , Endogenous Metabolite |
L-Homoserine ((S)-(-)-2-AMINO-4-HYDROXYBUTYRIC ACID) is a more reactive variant of the amino acid serine. In this variant, the hydroxyl side chain contains an additional CH2 group which brings the hydroxyl group closer t... | |||
TN4364 | Kadsuracoccinic acid A | Others | |
Kadsuracoccinic acid A has anticancer activity, it induces significant cleavage arrest. Kadsuracoccinic acid A may be related to the preservation of the progression of the M phase. | |||
T82649 | Cyanidin | ||
Cyanidin, an antioxidant, exhibits protective effects against DNA cleavage, demonstrates free radical scavenging activity, and significantly inhibits xanthine oxidase (XO) activity [1]. | |||
T19169 | 9-cis-Retinal | Others | |
T79978 | 6,6′-Dihydroxythiobinupharidine | ||
6,6′-Dihydroxythiobinupharidine, a cysteine proteases inhibitor, amplifies DNA cleavage facilitated by human topoisomerase IIα and IIβ by approximately 8-fold and 3-fold, respectively [1] [2]. | |||
T80656 | Cannflavin A | ||
Cannflavin A, isolated from Cannabis sativa L., exhibits anti-cancer, neuroprotective, and anti-inflammatory activities by inhibiting Aβ1-42 aggregation and kynurenine-3-monooxygenase (KMO), as well as inducing apoptosis... | |||
T73730 | Distamycin A | ||
Distamycin A (NSC-82150), an oligopeptide antibiotic, functions as a minor groove binder targeting B-form DNA, primarily at A/T-rich locations. It modifies enediyne-induced DNA cleavage sites and promotes apoptosis, as e... | |||
TN4046 | Excisanin A | MMP , FAK , PARP , GSK-3 , NF-κB , Wnt/beta-catenin , Akt , Caspase , PI3K , Prostaglandin Receptor , JNK | |
ExcisaninA may be a potent inhibitor of AKT signaling pathway in tumor cells, it can inhibit invasion by suppressing MMP-2 and MMP-9 expression, it may be a potential anti-metastatic chemotherapeutic agent for the treatm... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-03503 | GCSH Protein, Human, Recombinant (His) | Human | E. coli |
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoi... | |||
TMPY-04009 | Influenza A H7N9 (A/Shanghai/1/2013) Hemagglutinin/HA Protein (HA1+HA2, cleavage, His) | H7N9 | HEK293 |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPY-04008 | Influenza A H7N9 (A/Anhui/1/2013) Hemagglutinin/HA Protein (HA1+HA2, cleavage, His) | H7N9 | HEK293 |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPH-01084 | CYP11A1 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholester... | |||
TMPH-03712 | Clp1 Protein, Xenopus laevis, Recombinant (His) | Xenopus laevis | E. coli |
Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated mo... | |||
TMPH-01056 | Caspase-3 Protein, Human, Recombinant (His) | Human | E. coli |
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activ... | |||
TMPK-00383 | ACE2/ACEH Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angio... | |||
TMPY-03878 | Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) | Human | HEK293 |
Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in th... | |||
TMPY-04643 | Integrin alpha V beta 6 Protein, Mouse, Recombinant (Flag & His) | Mouse | HEK293 |
Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in th... | |||
TMPY-00978 | Progranulin Protein, Human, Recombinant (His) | Human | HEK293 |
Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The precursor protein, progranulin, ... | |||
TMPJ-00254 | TGF beta 3 Protein, Human/Mouse/Rat, Recombinant | Human,Mouse,Rat | Human Cells |
Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted as a complex with LAP. This latent form of TGFB3becomes acti... | |||
TMPY-05717 | Integrin alpha V beta 8 Protein, Human, Recombinant (His) | Human | HEK293 |
Integrin alpha V beta 8 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. ITGAVB8 does not appear to assume different activation states; and the cytoplasmic tail does not connect to the cyto... | |||
TMPY-01906 | SEMA4D Protein, Human, Recombinant (His) | Human | HEK293 |
Semaphorin 4D (SEMA4D or CD100) is a member of the semaphorin family of proteins and an important mediator of the movement and differentiation of multiple cell types, including those of the immune, vascular, and nervous ... | |||
TMPY-02130 | Argonaute-2 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus-Insect Cells |
Argonaute 2 (AGO2), also known as Eukaryotic translation initiation factor 2C2 (EIF2C2), belongs to the Argonaute family, AGO subfamily, which is a component of the RNA-induced silencing complex (RISC) and mediates small... | |||
TMPY-01186 | Argonaute-2 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Argonaute 2 (AGO2), also known as Eukaryotic translation initiation factor 2C2 (EIF2C2), belongs to the Argonaute family, AGO subfamily, which is a component of the RNA-induced silencing complex (RISC) and mediates small... | |||
TMPJ-00147 | FOLR1 Protein, Human, Recombinant (hFc) | Human | Human Cells |
Folate receptor alpha(FOLR) belongs to the folate receptor family, and is primarily expressed in tissues of epithelial origin. It is also expressed in kidney, lung and cerebellum. The secreted form is derived from the me... | |||
TMPY-04727 | GDF-15 Protein, Human, Recombinant (His) | Human | Yeast |
Growth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertrophic regulatory factor in the heart. GDF-15 / GDF15 is not... | |||
TMPY-01073 | GDF-15 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Growth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertrophic regulatory factor in the heart. GDF-15 / GDF15 is not... | |||
TMPY-02157 | GST Protein, Schistosoma japonicum, Recombinant | Schistosoma japonicum | Baculovirus-Insect Cells |
Genetic engineers have used glutathione S-transferase to create the GST gene fusion system. This system is used to purify and detect proteins of interest. In a GST gene fusion system, the GST sequence is incorporated int... | |||
TMPY-01395 | CTHRC1 Protein, Human, Recombinant (His) | Human | HEK293 |
Collagen triple helix repeat-containing protein 1, also known as Protein NMTC1, and CTHRC1, is a secreted protein that is glycosylated and highly conserved from lower chordates to mammals. CTHRC1 expression was not detec... | |||
TMPY-03937 | Influenza A H3N2 (A/Hong Kong/1/1968) Hemagglutinin/HA Protein (aa 1-530, His) | H3N2 | Baculovirus-Insect Cells |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPY-00109 | Influenza A H1N1 (A/WSN/1933) Hemagglutinin/HA Protein (His) | H1N1 | Baculovirus-Insect Cells |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPY-00314 | Influenza B (B/Yamagata/16/1988) Hemagglutinin/HA Protein (His) | Influenza B | Baculovirus-Insect Cells |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPY-05918 | Influenza A H1N1 (A/Guangdong-Maonan/SWL1536/2019)/(A/Hawaii/70/2019) Hemagglutinin/HA Protein (His) | H1N1 | HEK293 |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPY-01519 | Influenza A H1N1 (A/New Caledonia/20/1999) Hemagglutinin/HA Protein (His) | H1N1 | HEK293 |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPY-02343 | Influenza B (B/Brisbane/60/2008) Hemagglutinin/HA1 Protein (His) | Influenza B | HEK293 |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPY-05920 | Influenza A H3N2 (A/Kansas/14/2017) Hemagglutinin/HA Protein (His) | H3N2 | HEK293 |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPY-05908 | Influenza A H1N1 (A/swine/England/267/2007) Hemagglutinin/HA Protein (His) | H1N1 | HEK293 |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPY-00416 | Influenza A H10N8 (A/Jiangxi-Donghu/346/2013) Hemagglutinin/HA0 Protein | H10N8 | Baculovirus-Insect Cells |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPY-01301 | Influenza A H9N2 (A/Hong Kong/1073/99) Hemagglutinin/HA Protein (His) | H9N2 | HEK293 |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPY-01193 | Influenza A H1N1 (A/Brevig Mission/1/1918) Hemagglutinin Protein (His) | H1N1 | HEK293 |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPY-05823 | Influenza B (B/Colorado/06/2017) Hemagglutinin/HA Protein (His) | Influenza B | HEK293 |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPY-01242 | Influenza A H7N7 (A/Netherlands/219/2003) Hemagglutinin/HA Protein (His) | H7N7 | Baculovirus-Insect Cells |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPY-05533 | Influenza A H1N1 (A/Michigan/45/2015) Hemagglutinin/HA Protein (His) | H1N1 | HEK293 |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPY-04655 | Influenza A H5N6 (A/Sichuan/26221/2014) Hemagglutinin/HA Protein (His) | H5N6 | Baculovirus-Insect Cells |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPY-00012 | Influenza A H3N2 (A/Texas/50/2012) Hemagglutinin/HA1 Protein (His) | H3N2 | HEK293 |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPY-02524 | Influenza B (B/Brisbane/60/2008) Hemagglutinin/HA Protein (His) | Influenza B | HEK293 |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPY-00955 | Influenza B (B/Florida/4/2006) Hemagglutinin/HA Protein (His) | Influenza B | HEK293 |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPY-05922 | Influenza B (B/Washington/02/2019) Hemagglutinin/HA Protein (His) | Influenza B | HEK293 |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPY-05825 | Influenza A H3N2 (A/Hong Kong/4801/2014) Hemagglutinin/HA Protein (His) | H3N2 | Baculovirus-Insect Cells |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPY-01501 | Influenza A H1N1 (A/Puerto Rico/8/1934) Hemagglutinin/HA Protein (HEK293, His) | H1N1 | HEK293 |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPY-04701 | Influenza B (B/PHUKET/3073/2013) Hemagglutinin/HA0 Protein | Influenza B | Baculovirus-Insect Cells |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPY-05010 | Influenza A H9N2 (A/Hong Kong/3239/2008) Hemagglutinin/HA1 Protein (His) | H9N2 | HEK293 |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPY-04658 | Influenza A H3N2 (A/Switzerland/9715293/2013) Hemagglutinin/HA0 Protein | H3N2 | Baculovirus-Insect Cells |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPY-02662 | Influenza A H10N8 (A/Jiangxi-Donghu/346/2013) Hemagglutinin/HA Protein (His) | H10N8 | Baculovirus-Insect Cells |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPY-05919 | Influenza A H1N1 (A/Brisbane/02/2018) Hemagglutinin/HA Protein (His) | H1N1 | HEK293 |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPY-00152 | Influenza A H3N2 (A/Texas/50/2012) Hemagglutinin/HA Protein (His) | H3N2 | Baculovirus-Insect Cells |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPY-00278 | Influenza A H3N2 (A/Victoria/361/2011) Hemagglutinin/HA Protein (His) | H3N2 | Baculovirus-Insect Cells |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPY-04783 | Influenza A H3N2 (A/Wuhan/359/1995) Hemagglutinin/HA Protein (His) | H3N2 | Baculovirus-Insect Cells |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPY-01129 | Influenza A H5N1 (A/Vietnam/1194/2004) Hemagglutinin/HA Protein (RERRRKKR to TETR, HA1+HA2, uncleaved, His) | H5N1 | HEK293 |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
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カタログ番号 | 製品名 | ||
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L8720 | Pyroptosis Compound Library | 1077 compounds | |
1077 types of active small molecules associated with pyroptosis for high-throughput and high-content screening. |