58
27
30
5
3
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
TP2333 | Cyclo(L-Pro-L-Tyr) | Others | |
Maculosin is a secondary metabolite of fungi and bacteria. | |||
T10904 | CWP232228 | Wnt/beta-catenin | |
CWP232228, a potent and selective Wnt / β-catenin signaling inhibitor, antagonizes the binding of β-catenin to T-cell factor (TCF) in the nucleus. CWP232228 inhibits the formation and metastasis of tumors by inhibiting t... | |||
T8505 | SC-236 | Sc 236 | Apoptosis , COX , PPAR |
SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively). | |||
T1090 | Perphenazine | Perphenazin,Etaperazine,Trilafon | CaMK , Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Histamine Receptor |
Perphenazine (Trilafon) is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties. | |||
T22443 | Triglycidyl isocyanurate | Tris(2,3-epoxypropyl) Isocyanurate,Teroxirone,TGIC,TGI | Apoptosis |
Triglycidyl isocyanurate (Teroxirone) is a triazene triepoxide with antineoplastic and antiangiogenic activity. It inhibits growth of human non-small cell lung cancer cells by activating p53. Triglycidyl isocyanurate alk... | |||
T1406 | Amantadine hydrochloride | 1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride | Dopamine Receptor , Influenza Virus |
Amantadine hydrochloride (CI-719) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A and Parkinson disease. | |||
T23867 | Cdc7-IN-7c | Cdc7 inhibitor-7c,Cdc7 inhibitor 7c,Cdc7 IN 7c | CDK |
Cdc7-IN-7c (Cdc7 inhibitor-7c) has antitumor activity and has inhibitory effect on liver cancer, lung cancer, kidney cancer, brain cancer and cervical cancer. | |||
T60226 | CT52923 | PDGFR | |
CT52923 is a selective, orally active antagonist of platelet-derived growth factor receptor (PDGFR), functioning as an ATP-competitive inhibitor. It has versatile applications for researching an array of pathological dis... | |||
T22136 | PRL-3 Inhibitor I | PRL-3 Inhibitor,BR-1 | Phosphatase , Others |
PRL-3 Inhibitor I (BR-1) is a phosphatase of regenerating liver 3 (PRL-3) inhibitor which blocks the migration and invasion of metastatic cancer cells. | |||
T27133 | DCLX069 | DCLX 069,DCLX-069 | Histone Methyltransferase |
DCLX069 is a potent and selective PRMT1 inhibitor. DCLX069 occupies the SAM binding pocket to exert the inhibitory effect. DCLX069 effectively blocks cell proliferation in breast cancer, liver cancer and acute myeloid le... | |||
T9939 | JMJD6 inhibitor WL12 | 2H-1-Benzopyran-2-one, 3-(3H-imidazo[4,5-c]pyridin-2-yl)-6-methyl-,ZINC6733033 | Others |
JMJD6 inhibitor WL12 (ZINC6733033) is a first-in-class JMJD6 inhibitor and was shown to be able to suppress JMJD6-dependent cancer cell proliferation including cervical and liver cancer cells, providing a small-molecule ... | |||
T18957 | D-Ala-Lys-AMCA hydrochloride | Others | |
D-Ala-Lys-AMCA hydrochloride is a known substrate of proton-coupled oligopeptide transporter 1 (PEPT1) that emits blue fluorescence. D-Ala-Lys-AMCA hydrochloride may be transported into Caco-2 cells and liver cancer cell... | |||
T9945 | MNK8 | 3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione | STAT |
MNK8 (3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione) is a potent STAT3 inhibitor that reduces the ability of STAT3 to bind to DNA and also has a good growth inhibition effect on liver cancer cells [1]. | |||
T62491 | STAT3-IN-13 | STAT | |
STAT3-IN-13 is a potent STAT3 inhibitor.STAT3-IN-13 has antiproliferative and anticancer activity and acts by binding to the structural domain of STAT3 SH2.STAT3-IN-13 inhibits the phosphorylation of STAT3 Y705, which in... | |||
TQ0141 | Taltobulin | HTI-286,SPA-110 | Apoptosis , Microtubule Associated |
Taltobulin (HTI-286) is a synthetic analog of the tripeptide cysteine, a microtubule protein inhibitor that inhibits liver tumor cell proliferation in vitro and tumor growth in vivo.Taltobulin is cytotoxic, induces mitot... | |||
T0078L | Lapatinib ditosylate monohydrate | Lapatinib ditosylate monohydrate,Lapatinib ditoluenesulfonate monohydrate,Lapatinib tosilate hydrate,Lapatinib tosilate,Tykerb,Tyverb | EGFR , Ferroptosis , Autophagy |
Lapatinib ditosylate (Lapatinib tosilate) monohydrate is a tyrosine kinase receptor inhibitor used in the therapy of advanced breast cancer and other solid tumors. Lapatinib ditosylate monohydrate therapy is associated w... | |||
T14091 | AC-73 | Autophagy | |
AC-73 is an orally available Cluster of Differentiation 147 (CD147) inhibitor with high bioavailability that selectively disrupts the dimerization of CD147 (the binding site is in the N-terminal IgC2 domain of CD147 incl... | |||
T0189L | Pemetrexed disodium | LY-231514,LY231514 disodium,Pemetrexed | Apoptosis , DHFR , DNA/RNA Synthesis , Antifolate , Autophagy |
Pemetrexed disodium (LY-231514) is a parenterally administered folate antagonist and antineoplastic agent, used in the treatment of non-small cell lung cancer and malignant mesothelioma. Pemetrexed disodium therapy has b... | |||
T83658 | SQLE-IN-1 | Antifungal | |
SQLE-IN-1 is a squalene epoxidase (SQLE) inhibitor with anti-tumor activity. It can inhibit the proliferation and migration of liver cancer cell line Huh7, inhibit the production of cellular cholesterol, and increase the... | |||
T0976 | Propoxur | Aprocarb,Propoxure,Baygon | AChR , Antifungal |
Propoxur (Propoxure) is an insecticide used to control cockroaches, flies, mosquitoes, and lawn and turf insects. Acute (short-term) exposure of humans to propoxur by ingestion leads to cholinesterase inhibition of red b... | |||
T69201 | Lophenol | Others | |
Lophenol has potent inhibitory activity against human cancer cell lines such as liver cancer, nasopharyngeal and colon cancer cells. | |||
T34757 | Symphytine | Others | |
Symphytine is a natural inducer of hepatic tumors. Symphytine interacts with DNA in liver endothelial cells and hepatocytes, resulting in DNA damage, mutation induction, and cancer development. | |||
T72740 | N-Octyl caffeate | Others | |
n-Octyl caffeate demonstrates anti-cancer and apoptosis-inducing properties in highly liver-metastatic murine colon 26-L5 carcinoma cell lines. | |||
T18958 | D-Ala-Lys-AMCA TFA (375822-19-8 free base) | D-Ala-Lys-AMCA TFA | Others |
D-Ala-Lys-AMCA TFA is a known substrate of proton-coupled oligopeptide transporter 1 (PEPT1) that emits blue fluorescence. D-Ala-Lys-AMCA TFA may be transported into Caco-2 cells and liver cancer cells. | |||
T61243 | MAT2A-IN-5 | Others | |
MAT2A-IN-5, a potent inhibitor of MAT2A, effectively targets the abnormally elevated expression of MAT2A found in various tumor types such as gastric, colon, liver, and pancreatic cancers. By reducing the proliferative a... | |||
T25611 | Lanatoside | Lantoside,ABC lanatoside complex | Others |
Lanatoside is an FDA-approved cardiac glycoside that has been identified as a candidate anti-dengue compound. It has also been found to promote atherosclerosis. It also has anti-tumor activity, inhibiting the growth of c... | |||
T61672 | MAT2A-IN-7 | Others | |
MAT2A-IN-7, a potent inhibitor of the enzyme MAT2A, demonstrates efficacy in targeting the abnormally elevated expression of MAT2A observed in gastric, colon, liver, and pancreatic cancers. Furthermore, MAT2A-IN-7 effect... | |||
T37584 | Tryptoquivaline D | Others | |
Tryptoquivaline D is a fungal metabolite that has been found inNeosartorya siamensisand has anticancer activity.1,2It induces nuclear chromatin condensation, a marker of apoptosis, in HCT116 colon and HepG2 liver cancer ... | |||
T18959 | D-Ala-Lys-AMCA | Others | |
D-Ala-Lys-AMCA is a known substrate of proton-coupled oligopeptide transporter 1 (PEPT1) that emits blue fluorescence. D-Ala-Lys-AMCA may be transported into Caco-2 cells and liver cancer cells. | |||
T27816 | Leucinostatin | A 20668,A20668,A-20668 | Others |
Leucinostatin is a peptide mycotoxins that have some potent effects on liver cells after oral administration. Leucinostatin is used as both antimicrobial and antitumor agents through interactions with the membrane phosph... | |||
T82458 | Epigenetic factor-IN-1 | Sirtuin | |
Epigenetic factor-IN-1 (40569Z) is an epigenetic factor inhibitor that exhibits potent binding affinity for SIRT7. It is utilized in the study of liver cancer [1]. | |||
T63975 | MAT2A-IN-1 | Others | |
MAT2A-IN-1 is a potent inhibitor of MAT2A and is capable of proliferative activity in MTAP-deficient cancer cells. MAT2A is expressed at unusually high levels in several tumour types, including gastric, colon, liver and ... | |||
T61801 | HIV-1 inhibitor-35 | Others | |
HIV-1 inhibitor-35 (compound 74) is a highly potent inhibitor of the HIV-1 virus, exhibiting EC50 values of 80 nM and 70 nM for LTR and CMV, respectively, in HEK293 cells. Additionally, HIV-1 inhibitor-35 demonstrates in... | |||
T79594 | COX-1/2-IN-5 | COX | |
COX-1/2-IN-5 (compound 2a) functions as a dual inhibitor of COX1/2, demonstrating inhibitory concentrations (IC50) of 2.650 μM and 0.958 μM, respectively, and exhibits anticancer activity by inhibiting liver cancer HepG2... | |||
T83433 | 1D228 | c-Met/HGFR | |
1D228, a c-Met/TRK inhibitor with antitumor properties, suppresses cyclin D1 to precipitate G0/G1 arrest, thereby inhibiting proliferation and migration of cancer cells. This compound is applicable in researching gastric... | |||
T35809 | C20 Sphingomyelin (d18:1/20:0) | Others | |
C20 Sphingomyelin is a naturally occurring sphingolipid. Levels of C20 sphingomyelin are upregulated in the hippocampus of rats with diabetes induced by streptozotocin and in human plasma where it is positively correlate... | |||
T84968 | Indium (III) thiosemicarbazone 5b | Others | |
Indium (III) thiosemicarbazone 5b is an anticancer compound demonstrating cytotoxicity against various cancer cell lines including A549, MCF-7 breast, cisplatin-resistant MCF-7/DDP breast, and Hl 7702 liver cancer cells,... | |||
T79919 | S-Adenosyl-L-methionine (1,4-butanedisulfonate) | Ademetionine (1,4-butanedisulfonate),S-Adenosyl methionine (1,4-butanedisulfonate),AdoMet (1,4-butanedisulfonate) | Endogenous Metabolite |
S-Adenosyl-L-methionine (SAMe) 1,4-butanedisulfonate functions as an orally active methyl group donor and serves as a dietary supplement known for its significant antidepressant properties. Additionally, it plays anti-pr... | |||
T79373 | A3AR agonist 2 | Adenosine Receptor | |
Compound 19, a selective A3 Adenosine Receptor (A3AR) agonist (K i : 22.1 nM), effectively stimulates β-arrestin2 recruitment with an EC 50 value of 4.36 nM. This compound is utilized in research pertaining to inflammato... | |||
T72861 | (6R)-ML753286 | Others | |
'(6R)-ML753286, an isomer of ML753286, is an orally active, selective Breast Cancer Resistance Protein (BCRP) inhibitor, demonstrating an IC50 of 0.6 μM. It exhibits high permeability and low to medium clearance in roden... | |||
T71097 | DC-120 | Others | |
DC-120 is an ATP competitive AKT kinase inhibitor that suppressed proliferation and induced apoptosis in liver cancer cells both in vitro and in vivo. DC120 blocked the phosphorylation of downstream molecules in the AKT ... | |||
T82617 | D-Ala-Lys-AMCA TFA | ||
D-Ala-Lys-AMCA TFA is a proton-coupled oligopeptide transporter 1 (PEPT1) substrate characterized by its emission of blue fluorescence. It has been demonstrated through fluorescence analysis that this compound can be tra... | |||
T35978 | Benastatin A | Others | |
Benastatin A is a polyketide synthase-derived benastatin that has been found inStreptomycesand has diverse biological activities.1,2,3It inhibits glutathione S-transferase (GST; Ki= 5 μM for the rat liver enzyme).2Benast... | |||
T69035 | Camostat free base | Others | |
Camostat, also known as FOY 305, is a serine protease inhibitor. Camostat is used in the treatment of some forms of cancer and is also effective against some viral infections, as well as inhibiting fibrosis in liver or... | |||
T61990 | Topoisomerase I/II inhibitor 3 | Others | |
Topoisomerase I/II inhibitor 3 (compound 7) is a potent dual inhibitor of topoisomerase I (Topo I) and II (Topo II) . By inhibiting PI3K /Akt/mTOR signaling pathway, Topoisomerase I/II inhibitor 3 can inhibit cell prolif... | |||
T72997 | HIF-2α-IN-7 | Others | |
HIF-2α-IN-7 is a hypoxia inducible factor 2α (HIF-2α) inhibitor. HIF-2α-IN-7 can inhibit HIF-2α with an EC 50 value of 6 nM. HIF-2α-IN-7 can be used for the research of various types of diseases including cancer , liver ... | |||
T79359 | Anticancer agent 147 | Ferroptosis | |
Compound 6j (Anticancer agent 147), a sophoridine derivative and ferroptosis inducer, promotes intracellular accumulation of Fe2+, reactive oxygen species (ROS), and malondialdehyde (MDA), enhances endoplasmic reticulum ... | |||
T79372 | A3AR agonist 1 | Adenosine Receptor | |
A3AR Agonist 1 (Compound 12), with a Ki of 25.8 nM, is a potent A3 adenosine receptor (A3AR) agonist that promotes β-arrestin2 recruitment with an effective concentration (EC50) of 5.17 nM. It serves as a research tool i... | |||
T79798 | PHD-IN-2 | HIF/HIF Prolyl-Hydroxylase | |
PHD-IN-2 (Compound 91), a potent PHD antagonist with an IC50 of less than 5 nM, effectively stimulates erythropoietin synthesis in HEP3B cells with an EC50 of less than 2.5 μM. It is applicable for research purposes acro... | |||
T78855 | Anticancer agent 157 | NO Synthase | |
Anticancer Agent 157 (compound 15) is a nitric oxide (NO) inhibitor with IC50 values of 0.62 μg/mL, exhibiting both anti-inflammatory and anticancer effects. It interacts with inducible NO synthase (iNOS) and caspase 8, ... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T5S1923 | Schisandrin C | Schizandrin-C,Wuweizisu-C | Apoptosis , Others , Virus Protease |
Schisandrin C (Wuweizisu-C) is a phytochemical lignan isolated from Schizandra chinensis Baill; shows anticancer-effects in human leukemia U937 cells. | |||
T3673 | Mollugin | Rubimaillin | HER , JAK |
Mollugin (Rubimaillin) may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upr... | |||
T3324 | Lycorine | Galanthidine,Narcissine,Amarylline,Belamarine,Licorine | Apoptosis , Virus Protease , Antibacterial , AChR , Fatty Acid Synthase |
Lycorine (Narcissine) inhibits protein synthesis and may inhibit ascorbic acid biosynthesis, although studies on the latter are controversial and inconclusive. | |||
T7060 | Amantadine | 1-Aminoadamantane,1-Adamantanamine,1-Adamantylamine | Others |
Amantadine (1-Aminoadamantane) is an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release, and blocks dopamine reuptake. | |||
TN1599 | Eburicoic acid | Eburicoicacid,MFCD00238594,ZINC4655149 | Antioxidant , TNF , NOS , NO Synthase , CCR , Immunology/Inflammation related |
Eburicoic acid (ZINC4655149) exhibits anti-inflammatory and antioxidant activity thereby protecting the liver from CCl4-induced hepatic damage and can be used in studies about anti-liver cancer. | |||
TQ0065 | Pseudobufarenogin | ψ-Bufarenogin | Others |
Pseudobufarenogin (ψ-Bufarenogin), a novel anti-tumor compound, suppresses liver cancer growth by inhibiting receptor tyrosine kinase-mediated signaling. | |||
TN1143 | 1-O-Acetyl britannilactone | Apoptosis , Antibiotic | |
1-O-Acetyl britannilactone is an agricultural fungicide that induces apoptosis and can be used in studies of liver injury and cancer. | |||
TN5770 | Gingerenone A | Nrf2 | |
Gingerenone A is an effective Nrf2-Gpx4 activator. It is a small molecule compound isolated from ginger. It has anti-cancer activity, can prolong the cell cycle of cancer cells, and can inhibit dextran sodium sulfate (DS... | |||
T5S0018 | Betulonic acid | (+)-Betulonic acid,Betunolic acid,Liquidambaric acid | Parasite , HSV |
1. Betulonic acid (Liquidambaric acid) amide stimulated the regenerative response in hepatocytes under conditions of combined toxic exposure and promoted recovery of their qualitative and quantitative characteristics, wh... | |||
TN2272 | Tigloylgomisin H | Nrf2 | |
Tigloylgomisin H represents a potential liver cancer prevention agent, it can significantly induce quinone reductase (QR) activity in Hepa1c1c7 mouse hepatocarcinoma cells, it functions as a novel monofunctional inducer ... | |||
TWS1977 | Kamebakaurin | Kamebakaurine | NF-κB |
1. Kamebakaurin (Kamebakaurine) has the ability to protect the liver from APAP-induced hepatotoxicity, presumably by both inhibiting the inflammatory response and oxidative stress. 2. Kamebakaurin inhibits the expression... | |||
T1660 | Silibinin | Silibinin A,Silybin,Silymarin I | Reactive Oxygen Species , Autophagy |
Silibinin (Silybin) is the major active constituent of silymarin, a standardized extract of the milk thistle seeds, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silicristin, silidianin an... | |||
T4S0797 | Berberine | Berberin,Umbellatine | Reactive Oxygen Species , Topoisomerase , Endogenous Metabolite , Antibacterial , Antibiotic , Autophagy |
1. Berberine (Umbellatine) is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism. 2. Berberine may as a broad-spectrum anti-microbial medicine, a complementary therapeutic agent for HIV/AIDS. 3.... | |||
T5S0754 | Isoquercetin | 3-Glucosylquercetin,Hirsutrin,Isoquercitrin,Quercetin 3-o-glucopyranoside | NF-κB , Wnt/beta-catenin , NO Synthase |
1. Isoquercetin (3-Glucosylquercetin) is a potential stimulator of bone mineralization used for prophylaxis of osteoporotic disorders. 2. Isoquercetin may be as a potential therapeutic agent against neurodegeneration in ... | |||
T37067 | 9-hydroxy Stearic Acid | HDAC | |
9-hydroxy Stearic Acid is a hydroxy fatty acid that is the active metabolite of 9-PAHSA. 9-hydroxy Stearic Acid is formed from 9-PAHSA through carboxyl ester lipase in the liver and pancreas. The 9-hydroxy Stearic Acid (... | |||
T6677 | Sophocarpine | ERK , p38 MAPK , NF-κB , TLR , COX , HER , JNK , STAT | |
Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects. | |||
TN2507 | 1,6,7-Trihydroxyxanthone | DNA/RNA Synthesis | |
1,6,7-Trihydroxyxanthone has anti-cancer activity ,at least in part, through the activation of miR-218 and suppression of Bmi-1 expression; can suppress cell growth and induce apoptosis in liver cancer cells. | |||
T2S2104 | Sinigrin hydrate | Sinigrin monohydrate,Allylglucosinolate monohydrate | Antibacterial |
Sinigrin hydrate (Allylglucosinolate monohydrate) has antimicrobial activity. Sinigrin hydrate (Allylglucosinolate monohydrate) exerts important anti-proliferative activities in carcinogen-induced hepatocarcinogenesis in... | |||
TN6062 | 1,3,9-Trimethyluric acid | ||
1,3,9-Trimethyluric acid exhibits in vitro cytotoxic activity against breast cancer (MCF-7), human neuroblastoma (SHSY5Y), human non-small cell lung cancer (A549) and human liver cancer (HEPG2) with IC50 value in the ran... | |||
TN2308 | Wilfortrine | BCL | |
Wilfortrine can induce liver cancer cell HepG2 apoptosis, but with no effect on the cell cycle, mainly by promoting Bax expression and inhibiting anti-apoptotic protein Bcl-2 expression. | |||
TN4291 | Isofuranodiene | IL Receptor , NOS | |
Isofuranodiene protects GalN/LPS-induced liver injury in SD rats, it may be a potential functional food ingredient for the prevention and treatment of liver diseases. Isofuranodiene has anticancer activity, by inhibiting... | |||
TN5013 | Shizukaol D | AMPK | |
Shizukaol D exerts a growth inhibition effect on liver cancer cells in a dose- and time-dependent manner by modulating wnt signalling pathway. Shizukaol D may be used to treat metabolic syndrome, it induces mitochondrial... | |||
TN4194 | Heliangin | IL Receptor , TNF , NF-κB , MAPK , Prostaglandin Receptor | |
Heliangin shows anti-inflammatory effects, it can inhibit lipopolysaccharide-induced inflammation through signaling NF-κB pathway on LPS-induced RAW 264.7 cells. Heliangin has anti-cancer activity, it exhibits cytotoxic... | |||
TN5901 | Cudratricusxanthone A | ||
Cudratricusxanthone A has potent anti-proliferative, antioxidative, and monoamine oxidase inhibitory effects, it also possesses anti-cancer activities and provide a basis for developing effective therapeutic agents to in... | |||
TN4223 | Homopterocarpin | Antifection | |
Homopterocarpin and Pterocarpus extract offer gastroprotection against indomethacin- induced ulcer by antioxidative mechanism and the modulation of gastric homeostasis, homopterocarpin may be responsible for, or contribu... | |||
T36000 | 3-Hydroxyterphenyllin | Others | |
3-Hydroxyterphenyllin is a p-terphenyl fungal metabolite originally isolated from A. candidus that has diverse biological activities, including antioxidant, antiproliferative, antibacterial, and antiviral properties.1,2,... | |||
T35624 | Ajoene | Others | |
Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities, including antibacterial, anticancer, antiplatelet, and antioxidant properties.1,2,3,4It is active against Gram-positive (MICs =... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPH-01091 | CHD1L Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catal... | |||
TMPH-01498 | HJURP Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
HJURP Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPY-02869 | MMP-12 Protein, Human, Recombinant (catalytic domain) | Human | E. coli |
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, ... | |||
TMPJ-00412 | VEGFR1/FLT-1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 ... | |||
TMPK-01477 | HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated | Human | HEK293 Cells |
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ... | |||
TMPK-01436 | HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled | Human | HEK293 Cells |
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ... | |||
TMPK-01478 | HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein, Human, MHC (His & Avi), Biotinylated | Human | HEK293 Cells |
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ... | |||
TMPK-01417 | HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled | Human | HEK293 Cells |
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ... | |||
TMPK-01520 | HLA-A*02:01&B2M&AFP (PLFQVPEPV) Tetramer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ... | |||
TMPK-01521 | HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ... | |||
TMPK-01484 | HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ... | |||
TMPK-01483 | HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated | Human | HEK293 Cells |
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ... | |||
TMPK-01482 | HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ... | |||
TMPK-01519 | HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ... | |||
TMPK-01515 | HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ... | |||
TMPK-01132 | PRL-1/PTP4A1 Protein, Human, Recombinant (His) | Human | E. coli |
Phosphatases of regenerating liver (PRL-1, PRL-2, and PRL-3, also known as PTP4A1, PTP4A2, and PTP4A3) control magnesium homeostasis through an association with the CNNM magnesium transport regulators. PRL-1 (PTP4A1) is ... | |||
TMPY-04205 | AGR3 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
Anterior gradient protein (AGR) 3 is a highly related homologue of pro-oncogenic AGR2 and belongs to the family of protein disulfide isomerases. AGR3 was found in breast, ovary, prostate, and liver cancer, it is associat... | |||
TMPY-02622 | Aldolase B Protein, Human, Recombinant (GST) | Human | E. coli |
The aldolase family members involved in metabolism and glycolysis are present in three isoforms: ALDOA, ALDOB, and ALDOC. Aldolases are differentially expressed in human tissues, and aberrant expression has been observed... | |||
TMPJ-01288 | KLF6 Protein, Human, Recombinant | Human | E. coli |
Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by ... | |||
TMPY-06226 | SLC39A6/LIV-1 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Along with the SLC30 family, SLC39 family members regulate zinc movement in cells. SLC39 metal ion transporters accumulate zinc into the cytosol. SLC39A6, also known as LIV-1, belongs to a new subfamily of Zrt, Irt-like ... | |||
TMPJ-01262 | UPRT Protein, Human, Recombinant (His) | Human | E. coli |
UPRT is a cytoplasmic enzyme which belongs to the UPRTase family. UPRT is highly expressed in leukocytes, liver, spleen and thymus, with lower expression in brain, lung and skeletal muscle. UPRTcatalyzes the conversion o... | |||
TMPY-02426 | UBE2D1 Protein, Human, Recombinant (His) | Human | E. coli |
Ubiquitin-conjugating enzyme E2 D1 (UBE2D1), a member of human E2 ubiquitin-conjugating enzymes, is closely related to SFT, which is short for stimulator of iron (Fe) transport. In other words, UbcH5A is significantly up... | |||
TMPY-02386 | PTP4A2 Protein, Human, Recombinant (GST) | Human | E. coli |
PRL-2 (Protein-tyrosine phosphatase of regenerating liver 2), also known as PTP4A2 (Protein tyrosine phosphatase type IVA, member 2), is a member of PTP family and has an important function in controlling cell growth. PR... | |||
TMPK-00336 | GPC3 Protein-VLP, Human, Recombinant | Human | E. coli |
Glypican-3 is a protein ,which is encoded by the GPC3 gene in humans.The protein core of GPC3 consists of two subunits, where the N-terminal subunit has a size of ~40 kDa and the C-terminal subunit is ~30 kDa.Glypican 3 ... | |||
TMPK-00337 | GPC3 Protein-VLP, Human, Recombinant (aa 438-554) | Human | HEK293 Cells |
Glypican-3 is a protein ,which is encoded by the GPC3 gene in humans.The protein core of GPC3 consists of two subunits, where the N-terminal subunit has a size of ~40 kDa and the C-terminal subunit is ~30 kDa.Glypican 3 ... | |||
TMPY-02757 | TWEAKR/TNFRSF12A Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Fn14 (tumor necrosis factor receptor superfamily, member 12A), also known as TNFRSF12A, is the receptor for TNFSF12/TWEAK. Fn14 shares 82% amino acid identity with the mouse sequence. It contains a signal peptide, an ext... | |||
TMPY-06821 | THRB Protein, Human, Recombinant (His) | Human | E. coli |
Thyroid hormone receptor beta (THRB), also known as TRbeta and NR1A2, belongs to the nuclear hormone receptor family. Featuring an N-terminal transactivation domain, a central DNA-binding domain, and a hormone/ligand-bin... | |||
TMPY-02100 | TEM7 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Plexin domain-containing protein 1, also known as tumor endothelial marker 3, tumor endothelial marker 7 and PLXDC1 and TEM3, is a secreted, cytoplasm and single-pass type I membrane protein that belongs to the plexin fa... | |||
TMPY-02796 | KIAA0101 Protein, Human, Recombinant (His) | Human | E. coli |
KIAA11, also known as p15(PAF), is a proliferating cell nuclear antigen-associated factor that interacts with proliferating cell nuclear antigen(PCNA). It was initially isolated in a yeast two-hybrid screen for PCNA bind... | |||
TMPJ-01212 | ULBP-1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Mouse ULBP1, also known as RAET1I and NKG2DL1, is a member of the ULBP/RAET1 gene family. ULBP1 plays an important role in immune responses, especially in cancer and infectious diseases, and is well-known to bind to NKG2... |
カタログ番号 | 製品名 | ||
---|---|---|---|
L2193 | Anti-Liver Cancer Compound Library | 1787 compounds | |
1787 species of compounds related to liver cancer that can be used in anti-liver cancer drug development and pharmacological studies. | |||
L5510 | Drug-induced Liver Injury (DILI) Compound Library | 1001 compounds | |
A unique collection of 1001 hepatotoxicity causing compounds, a powerful tool for drug toxicity study, can be used for HTS and HCS screening; | |||
L1120 | AMPK-Targeted Compound Library | 80 compounds | |
80 well-chosen unique AMPK-targeted small molecules; | |||
L2550 | Glutamine Metabolism Compound Library | 565 compounds | |
A unique collection of 565 glutamine metabolism related compounds can be used for high throughput screening (HTS) and high content screening (HCS), and also is an effective tool for research in glutamine metabolism and ... | |||
L4600 | Selected Plant-Sourced Compound Library | 3048 compounds | |
A unique collection of 3048 plant-sourced compounds that derived from 277 plant species for high throughput screening (HTS) and high content screening (HCS); |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T69758 | Flutamide-d7 | ||
Flutamide-d7 is intended for use as an internal standard for the quantification of flutamide by GC- or LC-MS. Flutamide is an androgen receptor antagonist and prodrug form of 2-hydroxy flutamide. Flutamide is converted ... | |||
TMIH-0521 | Silibinin-d3 | ||
Silibinin-d3 is a deuterated compound of Silibinin. Silibinin has a CAS number of 22888-70-6. Silibinin is the major active constituent of silymarin, a standardized extract of the milk thistle seeds, containing a mixture... | |||
T71055 | Albendazole-d7 | ||
Albendazole-d7 is intended for use as an internal standard for the quantification of albendazole by GC- or LC-MS. Albendazole is an orally bioavailable benzimidazole anthelmintic that is active against a variety of helmi... |