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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T4245 | IWP-4 | Inhibitor of Wnt Production-4 | Wnt/beta-catenin |
IWP-4 (Inhibitor of Wnt Production-4) is a potent Wnt inhibitor. | |||
T79981 | Nitric oxide production-IN-1 | NO Synthase | |
Nitric oxide production-IN-1 (Compound 1) is an inhibitor of nitric oxide (NO) production extracted from Tupistra chinensis. It effectively suppresses NO synthesis in rat abdominal macrophages upon stimulation with lipop... | |||
T11362 | Gamma-Secretase Modulators | γ-Secretase Modulators,Amyloid-β production inhibitor | Others |
gamma-Secretase Modulators serves as a useful treatment for Alzheimer's disease by inhibiting the production of Amyloid-β. Specifically, it acts as a gamma-Secretase Modulators with an IC50 value. | |||
T21865 | BC 11-38 | PDE | |
BC 11-38 is a potent, selective PDE biodepressant which is mainly effective against PDE11 (IC50 : 0.28 μM). | |||
T8533 | ML318 | Others , Antibiotic | |
ML318 is a biaryl nitrile PvdQ acylase inhibitor (IC50 of 20 nM for binding in the acyl-binding site). ML318 inhibits P. aeruginosa (PAO1) with IC50 of 19 μM. ML318 prevents pyoverdine production and limits the growth of... | |||
T0160 | Anagrelide | Anagrelida,Xagrid,Anagrelidum | PDE |
Anagrelide (Xagrid) is a Platelet-reducing Agent. The mechanism of action of anagrelide is as a Phosphodiesterase 3 Inhibitor. The physiologic effect of anagrelide is by means of Decreased Platelet Production. | |||
T14369 | AZD-0284 | ROR | |
AZD-0284 is an inverse agonist of the nuclear receptor RORγ. In development for the treatment of plaque psoriasis vulgaris and respiratory tract disorders[1]. | |||
T8869 | B355252 | Others | |
B355252 protects against cell death caused by glutamate-evoked oxidative stress. B355252 shows neuroprotective effect, potentiating nerve growth factor (NGF)-induced neurite outgrowth. | |||
T7779 | Nelfinavir | AG1341 | HIV Protease |
Nelfinavir (AG1341) is an antiretroviral drug used in the treatment of the human immunodeficiency virus (HIV) (Ki=2 nM). Nelfinavir is a broad-spectrum, anticancer agent. | |||
T23861 | CAY10526 | CAY-10526,BTH,CAY 10526 | Prostaglandin Receptor |
CAY10526 (BTH) is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB signaling pathway. | |||
T6001 | Nelfinavir Mesylate | Viracept,Nelfin,AG1343,AG 1343 Mesylate | HIV Protease |
Nelfinavir Mesylate (Viracept) is an effective HIV protease inhibitor (Ki: 2 nM). | |||
T10866 | Cot inhibitor-2 | TNF , MAPK | |
T2386 | Pirfenidone | S-7701,AMR-69,S-7701,AMR69 | CCR , TGF-beta/Smad |
Pirfenidone (AMR69) is an inhibitor for TGF-β production and TGF-β stimulated collagen production. Pirfenidone inhibits fibroblast, epidermal, platelet-derived, and transforming beta-1 growth factors, thereby slowing tum... | |||
T72322 | R 59-022 hydrochloride | DKGI-I hydrochloride,Diacylglycerol kinase inhibitor I hydrochloride,DKGI-I hydrochloride ; Diacylglycerol kinase inhibitor I hydrochloride | 5-HT Receptor , PKC |
R 59-022 hydrochloride (DKGI-I hydrochloride) is a 5-HT Receptor antagonist that activates protein kinase C (PKC).R 59-022 hydrochloride is a DGK inhibitor (IC50:2.8 µM) that inhibits the phosphorylation of OAG to OAPA.R... | |||
T0576 | Diethylaminoethoxyethanol | Others | |
Diethylaminoethoxyethanol is served in the production of cough medicine Toclase and so on. | |||
T1846 | Y-320 | Y320 | IL Receptor , Lipase , Interleukin |
Y-320 is a new phenylpyrazoleanilide immunomodulator. | |||
T29797 | AKB-6899 | AKB6899 | VEGFR , HIF/HIF Prolyl-Hydroxylase , HIF |
AKB-6899 is an inhibitor of prolyl hydroxylase domain 3 (PHD3) and increases the soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated macrophages. AKB-6899 leads to stabilization of HIF-2α which in... | |||
T1251 | Dicloralurea | Dichlorolurea,DCU | Others |
Dicloralurea (DCU) is a veterinary food additive that inhibits methane production in herbicide ruminants. | |||
T0644 | 3-Amino-5-methylisoxazole | Others | |
3-Amino-5-methylisoxazole is pharmaceutical intermediates, used in the production of sulfonamide drugs. | |||
T30219 | AVE-9488 | AVE 9488,AVE9488 | NOS , NO Synthase |
AVE-9488 is a novel endothelial NO synthase (eNOS) enhancer that upregulates eNOS expression, induces NO production, and may ameliorate portal hypertension. | |||
T39442 | AM-8123 | ||
AM-8123 is an APJ agonist with high oral bioavailability and potency. It effectively inhibits Forskolin-stimulated cAMP production and activates Gα proteins. This compound is valuable for cardiovascular disease research. | |||
T8640 | G6PDi-1 | Dehydrogenase | |
G6PDi-1 is an effective G6PD inhibitor. It depletes NADPH and decreases inflammatory cytokine production. | |||
T32658L | Leteprinim | AIT082 acid,AIT 082 acid,AIT-082 acid | Others |
Leteprinim (AIT 082 acid) is an hypoxanthine derivative that stimulates in vitro neurite outgrowth and the production of adenosine and neurotrophins from astrocytes. | |||
T14219 | Aminaftone | Aminaphthone | Endothelin Receptor |
Aminaftone, a derivative of 4-aminobenzoic acid, inhibits endothelin-1 (ET-1) production and can be used to study hypertension and systemic sclerosis. | |||
T8440 | LASSBio-1135 | TNF , TRP/TRPV Channel | |
LASSBio-1135 is an orally effective antagonist of TRPV1 and inhibitor of TNF-α production. | |||
T67907 | Nimucitinib | JAK | |
Nimucitinib is a Janus kinase (JAK) inhibitor that can be used to treat dry eye and promote tear production. | |||
T15561 | Imanixil | HOE-402(free base) | Others |
Imanixil is an inducer of the LDL receptor (LDLR) and it is also a potent cholesterol-lowering compound. It also inhibits very low density-lipoprotein (VLDL) production and consequently decreases atherosclerosis developm... | |||
T38423 | CL097 | CL097 | Reactive Oxygen Species , TLR |
CL097 is an effective agonist of TLR7 and TLR8. CL097 induces pro-inflammatory cytokines in macrophages and NADPH oxidase priming, thereby increasing the fMLF-stimulated ROS production. | |||
T13180 | TOK-8801 | Others | |
TOK-8801 is a synthetic dihydroimidazole thiazole carboxamide with immunomodulatory activity that eliminates the stimulatory effects of antibody production by removing T cells.CAS 번호128-63-63-5 | |||
T21853 | (E)-AG 556 | EGFR | |
AG 556 is a selective inhibitor of EGFR and blocks LPS-induced TNF-α production. | |||
T14673 | BMS 299897 | Beta Amyloid , Gamma-secretase | |
BMS 299897 is a sulfonamide γ-secretase inhibitor. It has an IC50 of 7 nM for Aβ production inhibition in HEK293 cells stably overexpressing amyloid precursor protein (APP). | |||
T5641 | RP-54745 | Interleukin | |
RP-54745, a potential antirheumatic compound. Inhibitor of macrophage stimulation and interleukin-1 production. | |||
T7517 | Tiadinil | Others , Antibacterial | |
Tiadinil, a plant activator of systemic acquired resistance, boosts the production of herbivore-induced plant volatiles. | |||
T77574 | ROS inducer 1 | ROS , Antibiotic | |
ROS inducer 1 is a small molecule compound with bactericidal activity that inhibits the production of ROS in Xanthomonas axonopodis pv. citri (Xac), Xanthomonas oryzae pv. oryzae (Xoo) and Pseudomonas syringae pv. actini... | |||
T24865 | Tenivastatin | L-654969,L654969,Simvastatin acid,L 654969,Simvastatin hydroxy acid | ROS , HMG-CoA Reductase |
Tenivastatin (Simvastatin acid) is an anti-hyperlipidemic HMG-CoA reductase inhibitor that inhibits the production of reactive oxygen species (ROS) and can be used in the study of primary hyperlipidemia. | |||
T8401 | Efonidipine hydrochloride monoethanolate | NZ-105 hydrochloride monoethanolate | Calcium Channel |
Efonidipine hydrochloride monoethanolate (NZ-105 hydrochloride monoethanolate) is a Ca(2+)-channel Blocker, Enhances the Production of Dehydroepiandrosterone Sulfate in NCI-H295R Human Adrenocortical Carcinoma Cells | |||
T36442L | (Hyp³)-Bradykinin acetate | (Hyp³)-Bradykinin acetate (37642-65-2 Free base) | Bradykinin Receptor |
(Hyp³)-Bradykinin acetate is an agonist of bradykinin B2 receptor and stimulates inositol phosphate production in cultured human fibroblasts. | |||
T20882 | 4-Nitrobenzoic acid | Kyselina p-nitrobenzoova,4Nitrobenzoic acid,Nitrodracylic acid,4 Nitrobenzoic acid | |
4-Nitrobenzoic acid (4Nitrobenzoic acid) is a pharmaceutical intermediate often found in the production of folic acid, DABA, PABA and dyes. | |||
T19480 | NO-prednisolone | NCX-1015 | IL Receptor |
NO-prednisolone (NCX-1015) is a compound that effectively stimulates the production of IL-10 in vivo. It is a Prednisolone derivative that releases nitric oxide (NO). | |||
T16132 | MRE3008F20 | cAMP , Adenosine Receptor | |
MRE3008F20 is a species-selective and potent adenosine A3 receptor (AA3R) antagonist that inhibits Cl-IB-MECA-induced cAMP production and can be used in glaucoma and asthma studies.CAS 번호13483-88-88-9 | |||
T4168 | Visomitin | SKQ1 | Reactive Oxygen Species |
Visomitin (SKQ1) is a mitochondria-targeted antioxidant that decreases transmembrane potential and production of reactive oxygen species (ROS). | |||
T11897 | Telotristat ethyl | LX1606 | Hydroxylase |
Telotristat ethyl (LX1606) is a orally-delivered inhibitor of tryptophan hydroxylase that reduces serotonin production. | |||
T27850 | LP-471756 | LP471756 | GPR |
LP-471756 is a specific antagonist of GPR139 and inhibits LP-360924-stimulated cAMP production (IC50 = 640 nM). | |||
T60004 | SRI-37330 | Others | |
SRI-37330 inhibits glucagon secretion and function, reduces hepatic glucose production, and reverses hepatic steatosis. | |||
T20110 | Ethylene thiourea | ETU,Imidazolidinethione,NCI C03372,NCIC03372,NCI-C03372 | Others |
Ethylene thiourea (NCIC03372) is a pesticide used in fruit and vegetable production. Ethylene thiourea is also used as a novel contrast agent for MRI studies based on proton chemical exchange-dependent saturation transfe... | |||
T11188L | Emixustat hydrochloride | ACU-4429 hydrochloride | Others |
Emixustat hydrochloride (ACU-4429 hydrochloride) strongly inhibits 11-cis-retinol production with IC50 values of 232 ± 3 nM. 11-cis-retinol Emixustat hydrochloride is a novel visual cycle modulator. | |||
T2652 | Molidustat | BAY 85-3934 | HIF/HIF Prolyl-Hydroxylase |
Molidustat (BAY 85-3934)(BAY-85-3934), an inhibitor of hypoxia-inducible factor (HIF) prolyl hydroxylase (PH), stimulates erythropoietin (EPO) production and the formation of red blood cells. | |||
T4982 | Benznidazol | Radanil,Benznidazole,Ro 71051,Ro 07-1051 | Antibiotic , Parasite |
Benznidazol (Benznidazole)e has an antiprotozoal activity by interfering with parasite protein biosynthesis, influencing cytokines production and stimulating host phagocytosis. | |||
T60625 | Tigulixostat | LR-19074,IBI-350,LC350189 | Xanthine Oxidase |
Tigulixostat (LC350189) is a novel xanthine oxidase inhibitor (XOI) that reduces uric acid production and may be used to study gout-related diseases. | |||
T72082 | Compound T72082(SC) | ROS | |
ROS-IN-1 is a mitochondrial ROS inhibitor that can be used to reduce oxidative stress or inhibit reactive oxygen species (ROS) production. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
TN2167 | Rutaevin | Reactive Oxygen Species , NO Synthase | |
Rutaevin shows the inhibitory activity on nitric oxide (NO) production in lipopolysaccharide-activated RAW264.7 macrophages, it may be as a valuable anti-inflammatory agent. | |||
TN1546 | Dactylorhin A | NO Synthase | |
Dactylorhin A, a succinate derivative ester isolated from the rhizomes of Gymnadenia conopsea, demonstrates a moderate inhibitory effect on nitric oxide (NO) production in RAW 264.7 macrophage cells. | |||
T5826 | Eupalinolide A | HSP | |
Eupalinolide B is a natural product ,and demonstrates potent cytotoxicity against A-549, BGC-823, SMMC-7721, and HL-60 tumour cell lines. | |||
T15686 | L-741626 | 3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole | Dopamine Receptor |
L-741626 (3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole) is a selective antagonist of D2 dopamine receptor (Ki: 2.4, 100, and 220 nM for human D2, D3 and D4 receptors respectively). | |||
T4834 | Indole-3-acetamide | 3-Indoleacetamide,3-Indolylacetamide | Others , Endogenous Metabolite |
1H-Indole-3-acetamide (3-Indolylacetamide), also known as auxin amide or 2-(3-indolyl)acetamide, belongs to the class of organic compounds known as 3-alkylindoles. Within the cell, 1H-indole-3-acetamide is primarily loca... | |||
T1633 | β-Carotene | Carotaben,Beta-Carotene,Provitamin A | Apoptosis , ROS , Endogenous Metabolite |
β-Carotene (Provitamin A) is a naturally-occurring retinol (vitamin A) precursor obtained from certain fruits and vegetables with potential antineoplastic and chemopreventive activities. As an anti-oxidant, beta carotene... | |||
TN1109 | 3-O-Acetyl-16α-hydroxydehydrotrametenolic acid | 3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid | NOS , NO Synthase , Prostaglandin Receptor |
3-O-Acetyl-16α-hydroxydehydrotrametenolic acid (3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid) shows anti-inflammatory activity, it can inhibit NO production and iNOS expression in LPS-stimulated Raw264.7 cells. | |||
TN3176 | 6-Methoxynaringenin | NO Synthase | |
6-Methoxynaringenin is an aerial part of Scutellaria barbata D. Don (Lamiaceae) and inhibits NO production efficiently with an IC50 value of 25.8 μM. | |||
TN7229 | Baihuaqianhuoside | Praeroside | Others |
Baihuaqianhuoside (Praeroside) is a coumarin glycoside. Baihuaqianhuoside can be isolated from the roots of Passiflora and Hindenia solanacea and was first isolated from P. japonicum. Baihuaqianhuoside has anti-inflammat... | |||
T3779 | Crocin II | Crocin 2,Crocetin gentiobiosylglucosyl ester,Tricrocin,Crocin B | Caspase , COX , NO Synthase |
Crocin II (Crocetin gentiobiosylglucosyl ester) has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect of crocin is mainly mediated by reducing the protein expres... | |||
T5S1981 | Alpha-Cyperone | (+)-α-Cyperone,α-Cyperone | Others , Endogenous Metabolite |
1. alpha-Cyperone (α-Cyperone) is a promising inhibitor of Hla production by S. aureus and protects lung cells from this bacterium. 2. alpha-Cyperone significantly inhibited PGE2 production by suppressing the LPS-induced... | |||
T4S1616 | Sanggenon D | Sanggenone D | NOS , COX , GABA Receptor |
Sanggenone D represents a new scaffold of positive GABAA receptor modulators, it also inhibits COX-2 activity (IC 50 = 73-100 μM). Sanggenone D has anti-inflammatory activity, it can inhibit NO production from lipopolysa... | |||
TN1021 | Secologanic acid | NO Synthase | |
Secologanic acid is a plant growth inhibitor, it shows inhibition of nitric oxide production in lipopolysaccharide-activated macrophages. | |||
T13522 | 7-Ketolithocholic acid | 3α-Hydroxy-7-oxo-5β-cholanic acid | Endogenous Metabolite |
7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid) (3α-Hydroxy-7-oxo-5β-cholanic acid) is capable of absorption and serves to suppress the production of endogenous bile acid and the secretion of biliary cholester... | |||
T5727 | CAFESTOL | ERK , NF-κB , COX , PGE Synthase | |
CAFESTOL is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells. Cafestol has strong inhibitory activity on PGE2 production... | |||
T8010 | Dibutyl sebacate | Dibutyl decanedioate | Others |
Dibutyl sebacate (Dibutyl decanedioate) is an organic chemical which is mainly used as a plasticizer in the production of plastics. | |||
TQ0070 | Luteolin-3-O-beta-D-glucuronide | Others | |
Luteolin-3-O-beta-D-glucuronide is active in the inhibition of nitrite production in macrophages. | |||
T2O2741 | Thiamine monochloride | Thiamine chloride,Vitamin B1 | Others , Antioxidant , Endogenous Metabolite , Antibacterial |
Thiamine monochloride (Vitamin B1) is an essential vitamin with erythropoietic, glucose-regulatory, antioxidant, and mood-regulatory properties.Thiamine monochloride inhibits lead-induced lipid peroxidation, thereby prev... | |||
T0062 | Folic acid | Folate,Vitamin B9,Pteroylglutamic acid,Vitamin M,Folacin | DNA/RNA Synthesis , Endogenous Metabolite |
Folic acid (Vitamin B9)(Vitamin M; Vitamin B9) is indispensable for the production and maintenance of new cells, for DNA/RNA synthesis. | |||
T4972 | 2'-Deoxycytidine-5'-diphosphate trisodium | dCDP | Endogenous Metabolite |
2'-Deoxycytidine-5'-diphosphate trisodium (dCDP) is used as a substrate of CDP (nucleoside diphosphate) kinase (2.7.4.6) for the production of dCTP to support DNA biosynthesis and reverse transcription. | |||
T3S1089 | Phillygenin | Epipinoresinol methyl ether,(+)-Phillygenin,Phillygenol,Sylvatesmin,Forsythigenol | Reactive Oxygen Species |
1. Phillyrin, (+)-Phillygenin (Sylvatesmin), and (-)-phillygenin exert the strongest inhibitory activities on NO production with IC(5) values. | |||
T12588 | Pyridoxylamine | pyridoxamine | Endogenous Metabolite |
Pyridoxylamine (pyridoxamine) is an inhibitor of advanced glycation end production (AGEs) and lipoxidation end products (ALEs). | |||
T8949 | UDP-g acid | Others | |
UDP-g acid is a sugar used in the production of polysaccharides and is an intermediate in the biosynthesis of ascorbic acid | |||
T22312 | Dodecanedioic acid | Endogenous Metabolite | |
Dodecanedioic acid is a dicarboxylic acid used in the synthesis of the engineering plastic nylon 612.Dodecanedioic acid is used as a base oil in industrial production. | |||
TN6985 | Anhydronotoptol | 4-{[(2E,5E)-3,7-dimethylocta-2,5,7-trien-1-yl]oxy}-7H-furo[3,2-g]chromen-7-one | NO Synthase |
Anhydronotoptol (4-{[(2E,5E)-3,7-dimethylocta-2,5,7-trien-1-yl]oxy}-7H-furo[3,2-g]chromen-7-one), a natural compound extracted from the umbelliferae plant Qiangwu, is a potent inhibitor of nitric oxide production, inhibi... | |||
T8249 | Hexahydrofarnesyl acetone | Phytone | Others , Antibacterial |
Hexahydrofarnesyl acetone (Phytone) enhanced both the sticky materials production and cell growth, plays some role in the increase of sticky materials and cell growth. | |||
TN4228 | Hulupinic acid | NO Synthase | |
Hulupinic acid is the main oxidation product of hop acid, which may inhibit the production of NO in macrophages RAW 264.7 cells. | |||
TMO2681 | Xanthosine | 9-Beta-D-Ribofuranosylxanthine,Xanthine riboside | Others , Endogenous Metabolite |
Xanthosine (9-Beta-D-Ribofuranosylxanthine) is a xanthine nucleoside that increases the number of mammary stem cells and milk production in goats and cattle. | |||
TQ0301 | Kuwanon A | NO Synthase | |
T30086 | Anthragallol | Anthragallic acid,1,2,3-Trihydroxyanthraquinone | Others |
Anthragallol(1,2,3-Trihydroxyanthraquinone) displays cytotoxicity by binding to DNA.Anthragallol can be used as an analytical reagent in the production of brown pickling colors. | |||
T3S1944 | Darutoside | Darutin | Others |
1. Darutoside (Darutin) can as an appropriate treatment for wounds. 2. Darutoside can improve skin elasticity, surface appearance and stretch mark removal, through soothing the skin, decreasing inflammation, restoring co... | |||
TQ0218 | Deoxyandrographolide | 14-deoxyandrographolide | IL Receptor , TNF |
T40388 | Methyl 5-hydroxypyridine-2-carboxylate | Others | |
Methyl 5-hydroxypyridine-2-carboxylate, a phenolic acid identified in the stems of Mahonia fortune, demonstrates in vitro inhibitory effects on nitric oxide (NO) production. | |||
T2S2173 | (E)-Naringenin chalcone | Isosalipurpol,Chalconaringenin,trans-2'4'6'4-tetrahydroxychalcone | Others |
Naringenin chalcone (Isosalipurpol) has antiallergic activity Naringenin chalcone suppresses asthmatic symptoms by inhibiting Th2 cytokine production from CD4 T cells. Naringenin chalcone is a potent tomato flavonoid tha... | |||
T2S0765 | Epibetulinic acid | NO Synthase , Prostaglandin Receptor | |
Epibetulinic acid has anti-inflammatory activity, it exhibits potent inhibitory effects on NO and prostaglandin E(2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin. | |||
T14149 | AICAR phosphate | AICA Riboside phosphate,Acadesine phosphate | Mitophagy , NOS , YAP , AMPK |
AICAR phosphate (Acadesine phosphate) is an AMPK activator and inhibitor of autophagy, YAP, and mitophagy, as well as an adenosine analog that regulates glucose and lipid metabolism, and inhibits the production of pro-in... | |||
T5721 | Dehydroevodiamine hydrochloride | AChE | |
Dehydroevodiamine (DHE), a natural compound isolated from Evodia rutaecarpa, can inhibit AChE. It has hypotensive and neuroprotective effects and modulates nitric oxide production. | |||
T0129 | Sanguinarine chloride | Pseudochelerythrine chloride,Sanguinarium chloride | Apoptosis , EGFR , VEGFR , Antibacterial , Parasite , Autophagy |
Sanguinarine chloride (Pseudochelerythrine chloride), a benzophenanthridine alkaloid, stimulates apoptosis by activating the production of reactive oxygen species (ROS). | |||
T8014 | Epoxylinalool | 2-(2-Hydroxy-2-Propyl)-5-Methyl-5-Vinyltetrahydrofuran | Others |
Epoxylinalool (2-(2-Hydroxy-2-Propyl)-5-Methyl-5-Vinyltetrahydrofuran) is a naturally occurring monoterpene alcohol widely used in the production of perfumes and flavors. | |||
T5680 | Aloin(mixture of A&B) | MMP , IL Receptor , Antibacterial , Antifungal | |
ALOIN Inhibits Interleukin (IL)-1β-Stimulated IL-8 Production in KB Cells. | |||
T34295 | Resiniferatoxin | RTX,[3H]resiniferatoxin | IL Receptor |
Resiniferatoxin ([3H]resiniferatoxin) inhibits the production of Th1 cytokines, contributing to the defense against T. spiralis infection, and can be used in studies about the modulator of the immune response. | |||
T1116 | Biotin | Vitamin B7,D-Biotin,Vitamin H | |
Biotin (Vitamin H) is a water-soluble B-vitamin and is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids. | |||
T3915 | Ginsenoside Ro | Chikusetsusaponin 5,Polysciasaponin P3,Chikusetsusaponin V | Calcium Channel , Reductase , Prostaglandin Receptor |
Ginsenoside Ro (Chikusetsusaponin V) can reduce TXA2 production, weakly reduce COX-1 and TXAS activities, and has antiplatelet effects as a Ca2+ antagonist with an IC50 of 155 μM. | |||
T38475 | 2,6-Dimethylpyrazine | Others | |
2,6-Dimethylpyrazine is an indispensable flavor additive in the food industry and an important substrate for the production of hypoglycemic and antilipolytic compounds. | |||
T2228 | Adipic acid | Others , Endogenous Metabolite | |
Adipic acid is a precursor for the production of nylon. | |||
T4S2014 | 5,15-Diacetyl-3-benzoyllathyrol | Euphorbia factor L3 | Others |
1. 5,15-Diacetyl-3-benzoyllathyrol (Euphorbia factor L3) is a melanine production inhibitor, excellent in inhibiting pigment stagnation and improving the discoloration of the skin or freckles, has excellent stability. | |||
T2A2476 | L-Hydroxyproline | trans-4-Hydroxy-L-proline,L-Hydroxyprolin,Trans-4-Hydroxyproline | Endogenous Metabolite |
L-Hydroxyproline (L-Hydroxyprolin) is one of the hydroxyproline (Hyp) isomers. L-Hydroxyproline is a useful chiral building block in the production of many pharmaceuticals. | |||
TN6961 | Heneicosane | N-HENEICOSANE,henicosane | Antifungal |
Heneicosane (henicosane) is a pheromone that inhibits the production of aflatoxins. Heneicosane is an aroma component isolated from Streptomyces philanthi RL-1-178 or Serapias cordigera. | |||
T37341 | N-Acetyltyramine | Antibacterial | |
N-acetyltyramine is a metabolite of the biogenic amine tyramine . It enhances cytotoxicity of doxorubicin in resistant P388 murine leukemia cells with an IC50 value of 0.13 μg/ml compared with an IC50 value of 0.48 μg/ml... | |||
TN1373 | α-Humulene | Alpha-caryophyllene | TNF , NOS , COX |
α-Humulene (Alpha-caryophyllene) is extracted from S.officinalis essential oil.α-Humulene can inhibit tumor cell growth.α-Humulene also shows anti-inflammatory effects, probably by interfering with TNFalpha production an... | |||
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カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPJ-00235 | TPO Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. It produced by the liver and kidney which regulates the production of platelets. TPO stimulates the production and differentiation of me... | |||
TMPH-02569 | WISP2/CCN5 Protein, Mouse, Recombinant (His) | Mouse | P. pastoris (Yeast) |
May play an important role in modulating bone turnover. Promotes the adhesion of osteoblast cells and inhibits the binding of fibrinogen to integrin receptors. In addition, inhibits osteocalcin production. | |||
TMPJ-00387 | IL-4R alpha Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Interleukin-4 receptor subunit alpha(IL-4RA), alos known as Soluble IL-4 receptor subunit alpha, belongs to the type I cytokine receptor family and type 4 subfamily. It expressed in both Th1 and Th2 cells. It functions a... | |||
TMPK-00047 | IFN gamma Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Interferon-gamma (IFN gamma) is a cytokine that plays physiologically important roles in promoting innate and adaptive immune responses. The absence of IFN gamma production or cellular responsiveness in humans and experi... | |||
TMPH-02136 | SPSB1 Protein, Human, Recombinant (His) | Human | E. coli |
Substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Nega... | |||
TMPY-01648 | TREML2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Trem-like transcript 2 protein, also known as Triggering receptor expressed on myeloid cells-like protein 2, TREML2 and TLT2, is a single-pass type I membrane protein that contains one Ig-like V-type (immunoglobulin-like... | |||
TMPJ-00327 | M-CSF/CSF1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Macrophage Colony-Stimulating Factors (m-csf) are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and th... | |||
TMPY-03407 | NQO1 Protein, Human, Recombinant (His) | Human | E. coli |
NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-... | |||
TMPJ-01172 | IL-17 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Mature mouse IL-17A shares 61% and 89% amino acid seque... | |||
TMPY-02779 | Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His) | Human | Baculovirus Insect Cells |
Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoant... | |||
TMPJ-01467 | Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. OSM encodes a growth regulator, ... | |||
TMPJ-01466 | Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His) | Human | HEK293 Cells |
TNFRSF11B is a secreted protein, containing 2 death domains and 4 TNFR-Cys repeats. TNFRSF11B is a decoy receptor for the receptor activator of nuclear factor kappa B ligand (RANKL). By binding RANKL, TNFRSF11B inhibits ... | |||
TMPY-02904 | TLR4 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
TLR4, also known as TLR-4, is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans... | |||
TMPY-02030 | CD82 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetras... | |||
TMPY-02219 | Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His) | H1N1 | E. coli |
The NS1 Influenza protein is created by the internal protein-encoding, linear negative-sense, single-stranded RNA, NS gene segment and which also codes for the nuclear export protein or NEP, formerly referred to as the N... | |||
TMPK-00076 | IL-18 Protein (Primary Amine Labeling), Human, Recombinant, Biotinylated | Human | E. coli |
Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop... | |||
TMPH-01547 | Interferon alpha 21/IFNA21 Protein, Human, Recombinant (His) | Human | E. coli |
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. | |||
TMPH-01544 | Interferon alpha 14/IFNA14 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. | |||
TMPH-02806 | Nav3 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
May regulate IL2 production by T-cells. May be involved in neuron regeneration. | |||
TMPH-02585 | ACOD1 Protein, Mouse, Recombinant (His & Myc) | Mouse | Baculovirus Insect Cells |
Cis-aconitate decarboxylase that catalyzes production of itaconate and is involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory inna... | |||
TMPK-00661 | IL-22 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeab... | |||
TMPJ-00070 | IL-18 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Interleukin-18 is a secreted protein and it belongs to the IL-1 family. IL-18 is a proinflammatory cytokine and produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The c... | |||
TMPH-02299 | UGP2 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen. | |||
TMPH-02883 | RBFOX3 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Pre-mRNA alternative splicing regulator. Regulates alternative splicing of RBFOX2 to enhance the production of mRNA species that are targeted for nonsense-mediated decay (NMD). | |||
TMPH-03215 | TNFSF4 Protein, Rabbit, Recombinant (hFc) | Rabbit | HEK293 Cells |
Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production. TNFSF4 Protein, Rabbit, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight ... | |||
TMPK-01194 | IL-22 Protein, Mouse, Recombinant (His & Avi), Biotinylated | Mouse | E. coli |
The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeab... | |||
TMPH-03216 | TNFSF4 Protein, Rabbit, Recombinant (His) | Rabbit | E. coli |
Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production. TNFSF4 Protein, Rabbit, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular we... | |||
TMPH-02570 | WISP2/CCN5 Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
May play an important role in modulating bone turnover. Promotes the adhesion of osteoblast cells and inhibits the binding of fibrinogen to integrin receptors. In addition, inhibits osteocalcin production. | |||
TMPH-03116 | IL-4R Protein, Pig, Recombinant (His) | Sus scrofa (Pig) | E. coli |
Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production a... | |||
TMPY-05058 | TMX1 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
As a thiol-based tumor suppressor, TMX1 increases mitochondrial ATP production and apoptosis progression. TMX1 is the first example of a topology-specific client protein redox catalyst acting both in the folding and in t... | |||
TMPH-00784 | Intimin Protein, Hafnia alvei, Recombinant (His & SUMO) | Hafnia alvei | E. coli |
Necessary for the production of attaching and effacing lesions on tissue culture cells. Intimin Protein, Hafnia alvei, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predict... | |||
TMPH-03214 | TNFSF4 Protein, Rabbit, Recombinant (His & Myc) | Rabbit | P. pastoris (Yeast) |
Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production. TNFSF4 Protein, Rabbit, Recombinant (His & Myc) is expressed in yeast with C-6xHis, Myc tag. The predicted molecular weight is 1... | |||
TMPK-00317 | IL-18R alpha Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced I... | |||
TMPK-00512 | IL-18R alpha Protein, Cynomolgus, Recombinant (aa 22-329, His) | Cynomolgus | HEK293 Cells |
Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced I... | |||
TMPK-00077 | EPO/Erythropoietin Protein, Human, Recombinant | Human | HEK293 Cells |
Erythropoietin (EPO) is a circulating hormone conventionally considered to be responsible for erythropoiesis. In addition to facilitating red blood cell production, EPO has pluripotent potential, such as for cognition im... | |||
TMPH-01545 | Interferon alpha 16/IFNA16 Protein, Human, Recombinant (His) | Human | E. coli |
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. Interferon alpha 16/IFNA16 Protein, Human, Recombinant... | |||
TMPH-00276 | Interferon alpha-G/IFNAG Protein, Bovine, Recombinant (His & SUMO) | Bovine | E. coli |
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. Interferon alpha-G/IFNAG Protein, Bovine, Recombinant ... | |||
TMPH-02685 | GPHB5 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Functions as a heterodimeric glycoprotein hormone with GPHA2 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Plays a central role in controlling thyroid ce... | |||
TMPJ-00617 | IL-33 Protein, Rhesus macaque, Recombinant (His) | Rhesus | E. coli |
Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes, but almost undetectable in placenta. IL33 induces the pr... | |||
TMPY-03172 | Argininosuccinate lyase Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
The recycling of citrulline by argininosuccinate synthase 1 (ASS1) and argininosuccinate lyase (ASL) is crucial to maintain arginine availability and nitric oxide (NO) production. Nitric oxide (NO) plays an established r... | |||
TMPY-04170 | DEFB1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
The DEFB1 gene, encoding for the constitutively expressed human beta-defensin 1 (hBD1) antimicrobial peptide is a potential candidate when studying genetic susceptibility to caries. DEFB1 genetic variations have been rep... | |||
TMPH-01603 | Lanosterol synthase/LSS Protein, Human, Recombinant (His) | Human | E. coli |
Key enzyme in the cholesterol biosynthesis pathway. Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Through the production of lanosterol may regulate lens prote... | |||
TMPH-01348 | FSHR Protein, Human, Recombinant (His) | Human | HEK293 Cells |
G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. FSHR Protein, Human, Recombinant (His) is expresse... | |||
TMPK-00136 | ULBP-2 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, E... | |||
TMPH-03481 | FimH Protein, Salmonella typhimurium, Recombinant (His & Myc) | Salmonella typhimurium | E. coli |
Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). A mannose-binding adhesin. FimH Protein, Salmonella typhimurium, Recombinant (His & Myc) i... | |||
TMPK-00316 | IL-18R alpha Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced I... | |||
TMPH-03664 | Vaccinia virus (strain Western Reserve) OPG161 Protein (His) | VACV | P. pastoris (Yeast) |
Coordinates the incorporation of A36 into wrapped enveloped virion (EV) membranes and, subsequently, the production of actin tails. Therefore plays an essential role in efficient cell-to-cell spread of viral particles. V... | |||
TMPJ-00611 | SFP Protein, B.subtilis, Recombinant (His) | Bacillus subtilis | E. coli |
The Bacillus subtilis enzyme Sfp, required for production of the lipoheptapeptide antibiotic surfactin, posttranslationally phosphopantetheinylates a serine residue in each of the seven peptidyl carrier protein domains o... | |||
TMPK-01263 | B7-H7 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
B7-H7, also known as HHLA2 (HERV-H LTR-associating 2), is a member of the B7 family of immune regulatory proteins.Through interaction with TMIGD2, costimulates T-cells in the context of TCR-mediated activation. Enhances ... | |||
TMPH-01347 | FSHR Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. FSHR Protein, Human, Recombinant (E. coli, His) is... | |||
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