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Search Results for " bone "

ターゲット

Epigenetic Reader Domain

255

阻害剤

天然化合物

539

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T1973	PFI-4	PFI4	Epigenetic Reader Domain
	PFI-4 is a potent and selective and cell-permeable BRPF1 bromodomain inhibitor.		Epigenetic Reader Domain
T1850	Balicatib	AAE581	Cysteine Protease
	Balicatib (AAE581) is a potent and selective inhibitor of cathepsin K, used in trials studying the treatment of osteoporosis.		Cysteine Protease
T8550	NDMC101		Others , NF-κB , Proteasome
	NDMC101 is an inhibitor of dipeptidyl peptidase-IV activity in human T cells and exhibits immunomodulatory effects. It also acts as a novel inhibitor of NFATc1 and NF-κB activity.		Others , NF-κB , Proteasome
T22702	CYM 50769		Neuropeptide W
	CYM 50769 is a neuropeptide W/B receptor 1 (NPBWR1, GPR7) antagonist(IC50 = 0.12 μM). CYM 50769 inhibited NPW activation of NPBWR1 with a submicromolar IC50, and displayed high selectivity against a broad array of off-ta...		Neuropeptide W
T7469	Alendronic Acid	alendronate	Others
	Alendronic Acid (alendronate) is a nonhormonal medication used for osteoporosis, osteogenesis imperfecta, and several other bone diseases.		Others
T39508	KY-02327		Others
	KY-02327, a metabolically stabilized analog of KY-02061, serves as a potent inhibitor of the Dishevelled (Dvl)-CXXC5 interaction. This compound activates the Wnt/β-catenin pathway, thereby promoting osteoblast differenti...		Others
T38776	LP-922056		Wnt/beta-catenin
	LP-922056 is an inhibitor of Notum Pectinacetylesterase with EC50 values of 21 nM, 55 nM for human and mouse, respectively.		Wnt/beta-catenin
T2121	SW033291		Dehydrogenase
	SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues.		Dehydrogenase
T21616	L-006235	L 006235	Cysteine Protease
	L-006235 is a potent and reversible inhibitor of cathepsin K with IC50 of 0.25 nM.		Cysteine Protease
T1867	Otenaproxesul	ATB 346	Apoptosis , COX
	Otenaproxesul (ATB 346) is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity.		Apoptosis , COX
T8645	PF-06446846		Others
	PF 06446846 is a potent and selective PCSK9 inhibitor		Others
T16159	Muramyl dipeptide	MDP	NOD
	Muramyl dipeptide (MDP) is a synthetic immunoreactive peptide, consisting of N-acetyl muramic acid attached to a short amino acid chain of L-Ala-D-isoGln. Muramyl dipeptide indirectly decreases osteoclast differentiation...		NOD
T6574	Lumiracoxib	Prexige,COX-189	COX
	Lumiracoxib (Prexige) is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. Phase 4.		COX
T13324	VUF11207 fumarate		CXCR , Arrestin
	VUF11207 fumarate is an agonist of CXCR7 and a high-potency ligand of CXCR7 (pKi: 8.1).		CXCR , Arrestin
T1817	GNF-2	GNF2	SARS-CoV , Bcr-Abl
	GNF-2 is a highly selective non-ATP competitive inhibitor of Bcr-Abl.		SARS-CoV , Bcr-Abl
T23383	SR11237	SR 11237	Others , RAR/RXR
	SR11237 is a Pan retinoid X receptor (RXR) agonist. SR11237 causes RXR/RXR homodimers to form and transactivate a reporter gene containing a RXR-response element.		Others , RAR/RXR
T2334	Avanafil	TA1790	PDE
	Avanafil (TA1790) is a selective inhibitor of phosphodiesterase type 5 (PDE5) and is used as therapy of erectile dysfunction.		PDE
T6451	Clodronic acid disodium salt	Loron,Clodronate Disodium,Lodronate	Others
	Clodronic acid disodium salt (Lodronate), a bisphosphonate, is a potent antiosteolytic agent which inhibits bone resorption.		Others
T1944	LDN-214117		ALK , TGF-beta/Smad
	LDN-214117 is a potent and selective ALK2 inhibitor.		ALK , TGF-beta/Smad
T23146	PHA 568487 free base	PHA 568487	AChR
	The quinuclidine PHA 568487 free base is an agonist of the alpha 7 nicotinic acetylcholine receptor that was designed to mitigate the bioactivation associated with the core scaffold and subsequently remove associated lia...		AChR
T21460	Teriparatide acetate	hPTH 1-34 (acetate salt),Parathar acetate,Forteo	Others
	Teriparatide acetate (Forteo) is a PHT agonist, with an IC50 of 2 nM in HEK293 cells.Teriparatide acetate is a recombinant form of parathyroid hormone. It is an effective anabolic (i.e., bone growing) agent used to treat...		Others
T6374	Alfacalcidol	Bondiol,Etalpha,1-hydroxy Vitamin D3,1.alpha.-Hydroxyvitamin D3,1-hydroxycholecalciferol	Others
	Alfacalcidol (Etalpha) (1-hydroxycholecalciferol; Alpha D3; 1.alpha.-Hydroxyvitamin D3) is a non-selective VDR activator medication.		Others
T15259	Evatanepag	CP-533536 free acid	Prostaglandin Receptor
	Evatanepag (CP-533536 free acid) is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM.CP-533536 demonstrated the ability to heal fractures when administered l...		Prostaglandin Receptor
T7566	GRGDSPK	EMD 56574	Others
	GRGDSPK (EMD 56574) is an inhibitory peptide for RGD-mediated adhesion between integrin and extracellular matrix molecules.		Others
T1925	PLX647		c-Fms , c-Kit
	PLX647 is a highly selective dual FMS/KIT kinase inhibitor (IC50: 28/16 nM).		c-Fms , c-Kit
T9026	MEISi-2	Benzoic acid, 4-hydroxy-, 2-[(Z)-(2-oxo-1(2H)-naphthalenylidene)methyl]hydrazide	Others
	MEISi-2 is a potent MEIS inhibitor (MEISi). MEISi-2 significantly inhibits MEIS-luciferase reporters in vitro.		Others
T29978	Amicibone	Amicibono
	Amicibone is a biochemical.
T8400	Pamidronic acid		Wnt/beta-catenin
	Pamidronic acid Leads to Bone Necrosis via Suppression of Wnt/β-Catenin Signaling in Human Bone Marrow Mesenchymal Stem Cells		Wnt/beta-catenin
T0308	Etidronic acid	HEDPA,Etidronate,HEDP	Apoptosis , Phosphatase , Others , HBV
	Etidronic acid (HEDP) is a diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.		Apoptosis , Phosphatase , Others , HBV
T13911	Tacalcitol monohydrate	Curatoderm monohydrate,TV 02 monohydrate,TV-02H monohydrate,1,24(R)-Dihydroxyvitamin D3 monohydrate	Cysteine Protease
	Tacalcitol monohydrate(Curatoderm monohydrate), a vitamin D3 analog that promotes bone development by regulating calcium ions, can be used to study psoriasis.		Cysteine Protease
T0575	1-Methylimidazole		Others
	1-Methylimidazole is a metabolite of 1-methyl-2-thioimidazole (methimazole) which inhibits bone resorption.		Others
T9603	MNITMT
	MNITMT is a potent immunosuppressive agent without bone marrow toxicity [1].
T0379	Risedronic Acid	Risedronate	Others , Transferase
	Risedronic Acid (Risedronate), a pyridinyl biphosphonate, can inhibit osteoclast-mediated bone resorption.		Others , Transferase
T77581	KM02894		GluR
	KM02894 is a glutamate release inhibitor. Cancer cells release high levels of glutamate that can disrupt normal bone turnover, which can lead to cancer-induced bone pain.KM02894 may be used in the study of tumor-related ...		GluR
T1641	Strontium ranelate	Distrontium renelate,S12911	Calcium Channel , CaSR
	Strontium ranelate (S12911), a strontium (II) salt of the ranelic acid, is a medication for osteoporosis. Studies indicate it can also slow the course of osteoarthritis of the knee. The drug is unusual in that it both in...		Calcium Channel , CaSR
T19415	Medronic acid	Methylenediphosphonic acid	Others
	Medronic acid (Methylenediphosphonic acid), a methylene-substituted bisphosphonate, exhibits affinity for and adherence to hydroxyapatite crystals within the bone matrix. Accumulating at sites of osteoid mineralization, ...		Others
T25492	Hepln-13	Hepln 13,Hepln13	c-Met/HGFR
	Hepln-13 is a hepsin inhibitor that acts by hindering prostate cancer bone metastasis.		c-Met/HGFR
T8489	Minodronic acid monohydrate		Transferase
	Minodronic acid monohydrate is an farnesyl diphosphate synthase inhibitor that acts as a bone resorption inhibitor.		Transferase
T0309	Ipriflavone	Osteofix	advanced glycation end products
	Ipriflavone (Osteofix) (Osteofix) is a feed additive and a catabolic agent. It is used to inhibit bone resorption.		advanced glycation end products
T6373	Alendronate sodium hydrate	G-704650,Alendronate,MK 217,Alendronate sodium trihydrate,G-704650 Adronat,Fosamax	Transferase
	Alendronate sodium hydrate (MK 217) is a nitrogen-containing bisphosphonate, which is an effective inhibitor of bone resorption. It is utilized for the treatment and prevention of osteoporosis.		Transferase
T4662	SJ000291942		TGF-beta/Smad
	SJ000291942 is an activator of the canonical bone morphogenetic proteins (BMP) signaling pathway.		TGF-beta/Smad
T7809L	Ipamorelin 2 Pivalic acid	NNC-26-0161	Others
	Ipamorelin 2 Pivalic acid (NNC-26-0161) is a growth-hormone-releasing peptide, induces longitudinal bone growth in rats.		Others
T20112	Triphenyl bismuth	NSC 465,NSC-465,NSC465	Others
	Triphenyl bismuth (NSC-465) is an additive for making biomedical resins visible on x-ray images and can be used as a radiopaque agent for orthopaedic bone cements.		Others
T29071	UR13870	Org 48762-0,POLB 001,UR-13870,UR 13870	p38 MAPK
	UR-13870 (Org 48762-0) is an orally active and selective inhibitor of p38 mitogen-activated protein kinase (MAPK), which prevents bone damage in collagen-induced arthritis in mice.		p38 MAPK
T2188	Thonzonium Bromide		Proton pump , Antibacterial , Autophagy
	Thonzonium bromide is a mono-cationic surfactant that is structurally similar to Farnesol as an antimicrobial agent. It inhibits proton transport in a dose-dependent manner (EC50=69 μM). It inhibits RANKL-induced osteocl...		Proton pump , Antibacterial , Autophagy
T6112	Doxercalciferol	TSA 840,Hectorol,1.alpha.-Hydroxyvitamin D2,1α-hydroxyvitamin D2	Others
	Doxercalciferol (TSA 840) is a synthetic vitamin D2 analog, suppressing parathyroid synthesis and secretion, used to treat secondary hyperparathyroidism and metabolic bone disease.		Others
T7566L1	GRGDSPK acetate	GRGDSPK acetate(111119-28-9 Free base)	Beta Amyloid
	GRGDSPK acetate shows inhibitory activity against integrin-fibronectin binding and can be used in research on integrins in bone formation and resorption.		Beta Amyloid
T1041	Risedronate Sodium	NE 58095 Sodium,Risedronic Acid Sodium	HBV , Transferase
	Risedronate Sodium (NE 58095 Sodium) is an aminobisphosphonate derivative of etidronic acid and CALCIUM CHANNEL BLOCKER that inhibits BONE RESORPTION and is used for the treatment of OSTEOPOROSIS.		HBV , Transferase
T21299	Zoledronic acid monohydrate	zoledronate,ZOL 446,CGP 42446,CGP42446A,Zoledronic acid hydrate	Apoptosis , Others , Autophagy
	Zoledronic acid monohydrate (CGP 42446) is a synthetic imidazole bisphosphonate analog with anti-bone-resorption activity.		Apoptosis , Others , Autophagy
T16859	SBI-425		Others
	SBI-425 is an effective and orally bioavailable inhibitor of tissue-nonspecific alkaline phosphatase (TNAP). SBI-425 effectively inhibits TNAP in the vasculature and improves cardiovascular parameters and survival withou...		Others

Compounds

PFI-4

T1973

Synonym: PFI4

Target: Epigenetic Reader Domain

Balicatib

T1850

Synonym: AAE581

Target: Cysteine Protease

NDMC101

T8550

Synonym:

Target: Others, NF-κB, Proteasome

CYM 50769

T22702

Synonym:

Target: Neuropeptide W

Target: Wnt/beta-catenin

SW033291

T2121

Synonym:

Target: Dehydrogenase

L-006235

T21616

Synonym: L 006235

Target: Cysteine Protease

Otenaproxesul

T1867

Synonym: ATB 346

Target: Apoptosis, COX

Synonym: Prexige,COX-189

Target: CXCR, Arrestin

GNF-2

T1817

Synonym: GNF2

Target: SARS-CoV, Bcr-Abl

SR11237

T23383

Synonym: SR 11237

Target: Others, RAR/RXR

Clodronic acid disodium salt

T6451

Synonym: Loron,Clodronate Disodium,Lodronate

Target: ALK, TGF-beta/Smad

Synonym: hPTH 1-34 (acetate salt),Parathar acetate,Forteo

Target: Others

Alfacalcidol

T6374

Synonym: Bondiol,Etalpha,1-hydroxy Vitamin D3,1.alpha.-Hydroxyvitamin D3,1-hydroxycholecalciferol

Target: Others

Evatanepag

T15259

Synonym: CP-533536 free acid

Target: Prostaglandin Receptor

Synonym: Benzoic acid, 4-hydroxy-, 2-[(Z)-(2-oxo-1(2H)-naphthalenylidene)methyl]hydrazide

Target: Wnt/beta-catenin

Etidronic acid

T0308

Synonym: HEDPA,Etidronate,HEDP

Target: Apoptosis, Phosphatase, Others, HBV

Tacalcitol monohydrate

T13911

Synonym: Curatoderm monohydrate,TV 02 monohydrate,TV-02H monohydrate,1,24(R)-Dihydroxyvitamin D3 monohydrate

Target: Cysteine Protease

Target: Others, Transferase

Synonym: Distrontium renelate,S12911

Target: Calcium Channel, CaSR

Medronic acid

T19415

Synonym: Methylenediphosphonic acid

Target: Others

Hepln-13

T25492

Synonym: Hepln 13,Hepln13

Target: c-Met/HGFR

Minodronic acid monohydrate

Target: advanced glycation end products

Alendronate sodium hydrate

T6373

Synonym: G-704650,Alendronate,MK 217,Alendronate sodium trihydrate,G-704650 Adronat,Fosamax

Target: TGF-beta/Smad

Ipamorelin 2 Pivalic acid

Synonym: NSC 465,NSC-465,NSC465

Target: Others

UR13870

T29071

Synonym: Org 48762-0,POLB 001,UR-13870,UR 13870

Target: Proton pump, Antibacterial, Autophagy

Doxercalciferol

T6112

Synonym: TSA 840,Hectorol,1.alpha.-Hydroxyvitamin D2,1α-hydroxyvitamin D2

Target: Others

GRGDSPK acetate

T7566L1

Synonym: GRGDSPK acetate(111119-28-9 Free base)

Target: Beta Amyloid

Risedronate Sodium

T1041

Synonym: NE 58095 Sodium,Risedronic Acid Sodium

Target: HBV, Transferase

Zoledronic acid monohydrate

T21299

Synonym: zoledronate,ZOL 446,CGP 42446,CGP42446A,Zoledronic acid hydrate

Target: Apoptosis, Others, Autophagy

カタログ番号	製品名	別名	ターゲット
T5751	Tigogenin		Others
	Tigogenin is one of steroidal sapogenins which is widely used for synthesizing steroid drugs. It might have protective effect on bone and be helpful in preventing the development of osteoporosis.		Others
T5S2129	Sciadopitysin		TNF , NF-κB
	Sciadopitysin may prevent the development of diabetic osteopathy, it exerts its therapeutic effects via upregulation of mitochondrial biogenesis.Sciadopitysin shows protective effects on antimycin A-induced toxicity in o...		TNF , NF-κB
T5575	Cycloastragenol	Cyclogalegenol,Astramembrangenin	Epigenetic Reader Domain , Telomerase
	Astramembrangenin (Cycloastragenol (Astramembrangenin)) is a triterpenoid saponin compound and a hydrolysis product of the main active ingredient in Astragalus membranaceus. Cycloastragenol (CAG) may have a novel therape...		Epigenetic Reader Domain , Telomerase
TN1494	Cimicifugoside H-1		Others
	Cimicifugoside H1 shows the protective function to cerebral neuron during cerebral ischemia.		Others
T4S0969	Obtusifolin		Antioxidant , NF-κB
	1. Obtusifolin has antioxidant properties and improves chemically induced diabetes and its complications by modulation of oxidative stress. 2. Obtusifolin suppresses phthalate esters-mediated bone resorption, thus may be...		Antioxidant , NF-κB
T2988	(-)-Epigallocatechin Gallate	Epigallocatechol Gallate,EGCG	Ferroptosis , Reactive Oxygen Species , HIV Protease , Mitochondrial Metabolism , Endogenous Metabolite , Autophagy
	(-)-Epigallocatechin Gallate (EGCG) is an antioxidant polyphenol flavonoid that inhibits telomerase and DNA methyltransferase. (-)-Epigallocatechin Gallate (EGCG) blocks the activation of EGF receptors and HER-2 receptor...
T2902	Costunolide	Costus lactone,NSC 106404,Costunolid,(+)-Costunolide	Apoptosis , Endogenous Metabolite , Telomerase
	Costunolide (Costus lactone) has anti-inflammatory and anti-oxidant properties and mediates apoptosis.		Apoptosis , Endogenous Metabolite , Telomerase
TN7036	N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide	(9Z,12Z,15Z)-N-[(3-Methoxyphenyl)methyl]-9,12,15-octadecatrienamide,Macamide Impurity 14	Wnt/beta-catenin
	N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide (Macamide Impurity 14) induces osteogenic differentiation and subsequent bone formation of mesenchymal stem cells by activating the canonical Wnt/β-catenin signaling pa...		Wnt/beta-catenin
T5712	Zerumbone		Antioxidant , HSV
	Zerumbone is a natural monocyclic sesquiterpene first isolated from rhizomes of the wild ginger Z. zerumbet.It has also been shown to have anti-oxidant and anti-inflammatory activities, contributing to immunomodulatory a...		Antioxidant , HSV
T24744	Rubone
	Rubone is the tumor suppressor miRNA-34a modulator that acts by inhibiting the growth of hepatocellular carcinoma.
T0912	Tetracycline hydrochloride	NCI-c55561,Tetracycline HCl	ribosome , Antibacterial , Antibiotic
	Tetracycline hydrochloride (NCI-c55561) is the hydrochloride salt of the tetracycline, a broad-spectrum naphthacene antibiotic produced semisynthetically from chlortetracycline, an antibiotic isolated from the bacterium ...		ribosome , Antibacterial , Antibiotic
T13768	(+)-Medicarpin		Estrogen/progestogen Receptor
	(+)-Medicarpin, a pterocarpan, is an isoflavonoid compound derived from multiple medicinal plant species such as Sophora japonica, Zollernia paraensis, Platymiscium yucatamun, Machaerium aristulatum, and Platymiscium flo...		Estrogen/progestogen Receptor
T3488	Tectorigenin	4',5,7-Trihydroxy-6-methoxyisoflavone,Tectorigenine	Apoptosis
	Tectorigenin (4',5,7-Trihydroxy-6-methoxyisoflavone) is an O-methylated isoflavone. Tectorigenin Promotes Osteoblast Differentiation and in vivo Bone Healing, but Suppresses Osteoclast Differentiation and in vivo Bone Re...		Apoptosis
TN1117	Veraguensin		p38 MAPK , NF-κB , Antibiotic , Parasite , Antifection
	Veraguensin is derived from Magnolia sp.. Veraguensin inhibits bone resorption and shows high antileishmanial activity.		p38 MAPK , NF-κB , Antibiotic , Parasite , Antifection
T2820	Glycitin	Glycitein-7-β-O-glucoside,Glycitein 7-O-β-glucoside	Others , Influenza Virus , Antibacterial
	Glycitin (Glycitein 7-O-β-glucoside), a natural isoflavone isolated from legumes, can promote the proliferation of bone marrow stromal cells and osteoblasts and suppresses bone turnover.		Others , Influenza Virus , Antibacterial
TJS0856	Dalbergin	6-Hydroxy-7-Methoxy-4-Phenylcoumarin	Others
	1. Dalbergin (6-Hydroxy-7-Methoxy-4-Phenylcoumarin) exhibits similar bone conserving effect against bone-loss as estradiol treatment, it as a therapeutic candidate against postmenopausal osteoporosis. 2. Dalbergin preven...		Others
T3S2312	Poncirin	Isosakuranetin-7-neohesperidoside	Apoptosis , Others
	1. Poncirin (Isosakuranetin-7-neohesperidoside) shows a significant in vitro inhibitory effect on the growth of the human gastric cancer cells, SGC-791, in a dose-dependent manner. 2. Poncirin prevents adipogenesis, enha...		Apoptosis , Others
T3004	Batilol	Batilolum,Stearyl monoglyceride,Batyl alcohol,1-O-Octadecylglycerol	Others , Endogenous Metabolite
	Batilol (Stearyl monoglyceride), isolated from shark liver oil, is also present in yellow bone marrow of animals and has been described as an inflammatory agent.		Others , Endogenous Metabolite
T8103	H-HoArg-OH		Endogenous Metabolite , Phosphorylase
	H-HoArg-OH, a homologue arginine, is a strong inhibitor of human liver and bone alkaline phosphatase.		Endogenous Metabolite , Phosphorylase
T9171	Methenolone enanthate		Others
	Methenolone enanthate is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of anemia due to bone marrow failure.		Others
T7437	3-(3-Hydroxyphenyl)propionic Acid	m-Hydroxyphenylpropionic acid,3-Hydroxyhydrocinnamic acid	Others , Endogenous Metabolite
	3-(3-Hydroxyphenyl)propionic Acid (m-Hydroxyphenylpropionic acid) is one of the major metabolites of ingested caffeic acid.it inhibited osteoclastogenesis and bone osteoclastic resorptive activity.		Others , Endogenous Metabolite
T3808	Icariside I	Lcariside I,Icariin I,Icarisid I	Others
	Icariside I (Lcariside I) is isolated from Epimedium herb. It can stimulate osteogenic differentiation of BMSCs and inhibit bone resorption activity of osteoclasts.		Others
T8117	Metenolone acetate	Methenolone acetate	Others , Androgen Receptor
	Metenolone acetate (Methenolone acetate) is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of anemia due to bone marrow failure.		Others , Androgen Receptor
T2980	Chondroitin sulfate	Chonsurid,Chondroitin polysulfate	MMP , Others , Endogenous Metabolite , NO Synthase
	Chondroitin sulfate (Chonsurid) is extracted from shark bone;Store the product in sealed, cool and dry condition		MMP , Others , Endogenous Metabolite , NO Synthase
T2845	Imperatorin	Ammidin,8-Isoamylenoxypsoralen,8-Isopentenyloxypsoralene,Marmelosin,Pentosalen	TRP/TRPV Channel , AChR , AChE , NOD
	Imperatorin (8-Isopentenyloxypsoralene) is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.		TRP/TRPV Channel , AChR , AChE , NOD
T5S0662	Gelsemine	Gelsemin	Antioxidant
	1. Gelsemine (Gelsemin) has antitumor activity. 2. Gelsemine has anti-oxidative activity. 3. Gelsemine has anti-hyperlipidemic activity. 4. Gelsemine has marked antinociception in inflammatory, neuropathic and bone cance...		Antioxidant
T6S1966	Curculigoside	Curculigoside A	Antioxidant , NF-κB , JAK , STAT
	1. Curculigoside (Curculigoside A) can prevent bone loss , improve osteogenesis and inhibit osteoclastogenesis of hAFSCs, suggesting its potential use to regulate hAFSC osteogenic differentiation for treating bone disord...		Antioxidant , NF-κB , JAK , STAT
TN3209	3′,4′,7-Trihydroxyflavone		ATPase , Others , p38 MAPK , NF-κB
	3'4'7-Trihydroxyflavone can markedly inhibit the receptor activator of nuclear factor kappa B ligand (RANKL) induced osteoclastic differentiation from mouse bone marrow derived macrophages (BMMs), it inhibits osteoclasto...		ATPase , Others , p38 MAPK , NF-κB
T3S0137	Bavachalcone		Antibacterial , Antibiotic
	Bavachalcone is a major bioactive compounds isolated from Psoralea corylifolia L. it may be useful as a therapeutic drug for bone resorption-associated diseases.Bavachalcone can protect the endothelial function by increa...		Antibacterial , Antibiotic
T3924	Astragaloside II	Astrasieversianin VIII	TGF-beta/Smad
	Astragaloside II (Astrasieversianin VIII) is an effective MDR reversal agent and may be a potential adjunctive agent for hepatic cancer chemotherapy. Astragaloside II also induces osteogenic activities, differentiation, ...		TGF-beta/Smad
T3777	Praeruptorin A	(+)-Praeruptorin A	CaMK , NF-κB
	Praeruptorin A ((+)-Praeruptorin A) has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin and inhibiting the Ca(2+)/calmodulin-CaMKIV-CREB-NFATc1 and/or...		CaMK , NF-κB
T3662	Eleutheroside E		NF-κB
	Eleutheroside E has anti-inflammatory effects by inhibiting NF-κB activities. Eleutheroside E significantly decreases the inflammatory cell infiltration, pannus formation, cartilage damage, bone erosion of CIA mice, the ...		NF-κB
TN1711	Gossypetin		Antioxidant , p38 MAPK , MAPK , Antibacterial
	Gossypetin, a hexahydroxylated flavonoid extractable from Rhodiola rosea Linn. is a potent MKK3 and MKK6 inhibitor that strongly attenuates the MKK3/6-p38 signaling pathway.Gossypetin exhibits antimutagenic, antiatherosc...		Antioxidant , p38 MAPK , MAPK , Antibacterial
T3804	Neomangiferin	Mangiferin 7-glucoside	Phosphatase
	Neomangiferin (Mangiferin 7-glucoside) has beneficial effects on high fat diet-induced nonalcoholic fatty liver disease in rats. Neomangiferin and mangiferin inhibit tartrate-resistant acid phosphatase, a biochemical mar...		Phosphatase
T3S1729	Dihydrolycorine		Others
	1. Dihydrolycorine-HCL(DL) shows hypotensive effects, it can block alpha 1-adrenoceptors. 2. Dihydrolycorine is an inhibitors of protein synthesis in eukarytic cells, it halts protein synthesis in eukaryotic cells by inh...		Others
T5770	Alisol B		RANKL/RANK
	Alisol B may be a potential novel therapeutic molecule for bone disorders through targeting the differentiation of osteoclasts as well as their functions. Alisol B also inhibited RANKL-induced expression of NFATc1 and c-...		RANKL/RANK
TN1918	Medicarpin		Apoptosis , BCL , ROS , JNK
	Medicarpin, a legume phytoalexin, acts as an estrogen receptor (ER) agonist, can stimulate osteoblast differentiation likely via ERα², promote achievement of peak bone mass, and is devoid of uterine estrogenicity; in add...		Apoptosis , BCL , ROS , JNK
T6316	Calcitriol	Topitriol,Rocaltrol,Calcijex,RO215535,1,25-Dihydroxyvitamin D3	Endogenous Metabolite
	Calcitriol (1,25-Dihydroxyvitamin D3) is a metabolite of vitamin D and a vitamin D receptor (VDR) agonist (IC50=0.4 nM). Calcitriol increases intestinal absorption of calcium and phosphorus, and increases bone resorption...		Endogenous Metabolite
T8194L	Soy Isoflavone		Others
	Soy Isoflavone is extracted from the seeds of leguminous plants. The isoflavones in soybeans are natural phytoestrogens, which have good medicinal value and can reduce the incidence of breast cancer in women, relieve men...		Others
T4237	Rubiadin-1-methyl ether	Rubiadin 1-methyl ether	Anti-infection , NF-κB
	Rubiadin-1-methyl ether (Rubiadin 1-methyl ether) is a natural product.It inhibits osteoclastic bone resorption via inhibition on the phosphorylation of NF-κB p65 and the degradation of IκBα as well as decrease in the nu...		Anti-infection , NF-κB
T3674	Hydroxysafflor yellow A	HSYA,Safflomin A	TGF-beta/Smad
	Hydroxysafflor yellow A (Safflomin A) inhibited adipogenesis by increasing HSL promoter activities. Hydroxysafflor yellow A can effectively protect the liver from long-term alcohol injury by enhancing antioxidant capacit...		TGF-beta/Smad
T2698	Asperosaponin VI	Akebia saponin D,Asperosaponin Ⅵ	Apoptosis , Others , Caspase
	Asperosaponin VI (Akebia saponin D) , the most abundant constituent of the rhizome of Dipsacus asper, has been used for the treatment of lower back pain, traumatic hematoma and bone fractures.		Apoptosis , Others , Caspase
TN1215	(2S)-2'-Methoxykurarinone	2'-Methoxykurarinone,2'-O-Methylkurarinone	Akt , Antifection
	(2S)-2'-Methoxykurarinone is isolated from the roots of Sophora flavescens. (2S)-2'-Methoxykurarinone has anti-inflammatory, antipyretic, antidiabetic, and antineoplastic effects. (2S)-2'-Methoxykurarinone inhibits osteo...		Akt , Antifection
T2818	Methyl Vanillate		Reactive Oxygen Species , Wnt/beta-catenin , Endogenous Metabolite
	Methyl vanillate is Hovenia Dulcis Thunb extract and its ingredient methyl vanillate activate Wnt/β-catenin pathway and increase bone mass in growing or ovariectomized mice. Methyl vanillate is considered to be a slightl...
T6S0139	Neobavaisoflavone		Apoptosis , DNA/RNA Synthesis
	1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can si...		Apoptosis , DNA/RNA Synthesis
T1549	Raloxifene hydrochloride	LY156758 hydrochloride,Raloxifene HCl,LY139481 hydrochloride,Keoxifene hydrochloride,LY156758 (Keoxifene) HCl	Estrogen Receptor/ERR , Others , MAO , Estrogen/progestogen Receptor , Autophagy
	Raloxifene hydrochloride (LY156758 hydrochloride) is a second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. It has estrogen agonist effects on bone and chol...
T20089	ATP	Atipi,ATP disodium salt hydrate,Triphosphoric acid adenosine ester,Ara-ATP,Triphosphaden,Adenosine triphosphate;Ara-ATP,Adenosine triphosphate	Endogenous Metabolite
	ATP (Adenosine triphosphate) provides cellular energy, participates in overall energy balance, and maintains intracellular homeostasis. ATP can act as an extracellular signaling molecule through interactions with specifi...		Endogenous Metabolite
T3O2749	L-Leucine	(S)-Leucine,Leu	mTOR
	L-Leucine ((S)-Leucine) is one of nine essential amino acids in humans (provided by food), L-Leucine is important for protein synthesis and many metabolic functions. L-Leucine contributes to regulation of blood-sugar lev...		mTOR
T4S1050	Pristimerin	Celastrol methyl ester	NF-κB , Antibacterial
	1. Pristimerin (Celastrol methyl ester) has anticancer activity , treatment with Pristimerin may be a potential strategy for the suppression of hypoxia-induced metastasis through the reversal of hypoxia-induced stem cell...		NF-κB , Antibacterial
T1257	Bestatin	Ubenimex	Others , Aminopeptidase , Antibacterial , Antibiotic , LTR
	Bestatin (Ubenimex) competitively inhibits many aminopeptidases, including B, N and leucine aminopeptidases. Ubenimex is a microbial metabolite and dipeptide with potential immunomodulatory and antitumor activities. Amin...		Others , Aminopeptidase , Antibacterial , Antibiotic , LTR
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天然物製品

Synonym: Cyclogalegenol,Astramembrangenin

Target: Epigenetic Reader Domain, Telomerase

Target: Antioxidant, NF-κB

(-)-Epigallocatechin Gallate

T2988

Synonym: Epigallocatechol Gallate,EGCG

Target: Ferroptosis, Reactive Oxygen Species, HIV Protease, Mitochondrial Metabolism, Endogenous Metabolite, Autophagy

Costunolide

T2902

Synonym: Costus lactone,NSC 106404,Costunolid,(+)-Costunolide

Target: Apoptosis, Endogenous Metabolite, Telomerase

N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide

TN7036

Synonym: (9Z,12Z,15Z)-N-[(3-Methoxyphenyl)methyl]-9,12,15-octadecatrienamide,Macamide Impurity 14

Target: Wnt/beta-catenin

zerumbone

T5712

Synonym:

Target: Antioxidant, HSV

Tetracycline hydrochloride

T0912

Synonym: NCI-c55561,Tetracycline HCl

Target: ribosome, Antibacterial, Antibiotic

(+)-Medicarpin

T13768

Synonym:

Target: Estrogen/progestogen Receptor

Tectorigenin

T3488

Synonym: 4',5,7-Trihydroxy-6-methoxyisoflavone,Tectorigenine

Target: p38 MAPK, NF-κB, Antibiotic, Parasite, Antifection

Glycitin

T2820

Synonym: Glycitein-7-β-O-glucoside,Glycitein 7-O-β-glucoside

Target: Others, Influenza Virus, Antibacterial

Dalbergin

TJS0856

Synonym: 6-Hydroxy-7-Methoxy-4-Phenylcoumarin

Target: Others

Poncirin

T3S2312

Synonym: Isosakuranetin-7-neohesperidoside

Target: Apoptosis, Others

Batilol

T3004

Synonym: Batilolum,Stearyl monoglyceride,Batyl alcohol,1-O-Octadecylglycerol

Target: Others, Endogenous Metabolite

H-HoArg-OH

T8103

Synonym:

Target: Endogenous Metabolite, Phosphorylase

Methenolone enanthate

T9171

Synonym:

Target: Others

3-(3-Hydroxyphenyl)propionic Acid

T7437

Synonym: m-Hydroxyphenylpropionic acid,3-Hydroxyhydrocinnamic acid

Target: Others, Endogenous Metabolite

Icariside I

T3808

Synonym: Lcariside I,Icariin I,Icarisid I

Target: Others

Metenolone acetate

T8117

Synonym: Methenolone acetate

Target: Others, Androgen Receptor

Chondroitin sulfate

T2980

Synonym: Chonsurid,Chondroitin polysulfate

Target: MMP, Others, Endogenous Metabolite, NO Synthase

Imperatorin

T2845

Synonym: Ammidin,8-Isoamylenoxypsoralen,8-Isopentenyloxypsoralene,Marmelosin,Pentosalen

Target: TRP/TRPV Channel, AChR, AChE, NOD

Synonym: Curculigoside A

Target: Antioxidant, NF-κB, JAK, STAT

3′,4′,7-Trihydroxyflavone

TN3209

Synonym:

Target: ATPase, Others, p38 MAPK, NF-κB

Bavachalcone

T3S0137

Synonym:

Target: Antibacterial, Antibiotic

Astragaloside II

T3924

Synonym: Astrasieversianin VIII

Target: TGF-beta/Smad

Praeruptorin A

T3777

Synonym: (+)-Praeruptorin A

Target: Antioxidant, p38 MAPK, MAPK, Antibacterial

Neomangiferin

T3804

Synonym: Mangiferin 7-glucoside

Target: Apoptosis, BCL, ROS, JNK

Calcitriol

T6316

Synonym: Topitriol,Rocaltrol,Calcijex,RO215535,1,25-Dihydroxyvitamin D3

Target: Endogenous Metabolite

Rubiadin-1-methyl ether

T4237

Synonym: Rubiadin 1-methyl ether

Target: Anti-infection, NF-κB

Hydroxysafflor yellow A

T3674

Synonym: HSYA,Safflomin A

Target: TGF-beta/Smad

Asperosaponin VI

T2698

Synonym: Akebia saponin D,Asperosaponin Ⅵ

Target: Apoptosis, Others, Caspase

(2S)-2'-Methoxykurarinone

TN1215

Synonym: 2'-Methoxykurarinone,2'-O-Methylkurarinone

Target: Akt, Antifection

Methyl Vanillate

T2818

Synonym:

Target: Reactive Oxygen Species, Wnt/beta-catenin, Endogenous Metabolite

Neobavaisoflavone

T6S0139

Synonym:

Target: Apoptosis, DNA/RNA Synthesis

Raloxifene hydrochloride

T1549

Synonym: LY156758 hydrochloride,Raloxifene HCl,LY139481 hydrochloride,Keoxifene hydrochloride,LY156758 (Keoxifene) HCl

Target: Estrogen Receptor/ERR, Others, MAO, Estrogen/progestogen Receptor, Autophagy

ATP

T20089

Synonym: Atipi,ATP disodium salt hydrate,Triphosphoric acid adenosine ester,Ara-ATP,Triphosphaden,Adenosine triphosphate;Ara-ATP,Adenosine triphosphate

Target: Endogenous Metabolite

L-Leucine

T3O2749

Synonym: (S)-Leucine,Leu

Target: mTOR

Pristimerin

T4S1050

Synonym: Celastrol methyl ester

Target: NF-κB, Antibacterial

Bestatin

T1257

Synonym: Ubenimex

Target: Others, Aminopeptidase, Antibacterial, Antibiotic, LTR

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-00680	BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc)	Human,Mouse,Rat,Rhesus,Canine	HEK293
	BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokin...
TMPY-03235	BST2 Protein, Human, Recombinant (His)	Human	HEK293
	BST2 was frequently overexpressed in GC tissues compared with the adjacent non-tumorous tissues, and high BST2 expression was correlated with tumor stage and lymphatic metastasis. Furthermore, in vitro experiments demons...
TMPY-06842	BMP-4 Protein, Human, Recombinant (E399D)	Human	E. coli
	BMP4 (bone morphogenetic protein-4)-directed differentiation of human embryonic stem cells (ESCd). Autophagy is a conserved catabolic process with complicated roles in tumor development. Bone morphogenetic protein 4 (BMP...
TMPY-00663	Alkaline Phosphatase/ALPL Protein, Human, Recombinant (His)	Human	HEK293
	Alkaline phosphatase (ALPL) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. The process of removing the phosphate group is cal...
TMPY-01059	BMPR2 Protein, Human, Recombinant (His)	Human	HEK293
	The bone morphogenetic protein type II receptor (BMPR-II, or BMPR2), a receptor for the transforming growth factor (TGF)-beta/bone morphogenetic protein (BMP) superfamily. Reduced expression or function of BMPR2 signalin...
TMPY-03297	BMP-2 Protein, Danio rerio (zebrafish), Recombinant	Danio rerio (zebrafish)	E. coli
	BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokin...
TMPY-00681	BMP-5 Protein, Human, Recombinant (hFc)	Human	HEK293
	Bone Morphogenetic Protein 5 (BMP-5) is a member of the structurally and functionally related bone morphogenetic proteins (BMPs) which constitute a novel subfamily of the transforming growth factor β (TGF-β) superfamily....
TMPY-01136	BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant	Human,Mouse,Rat,Rhesus,Canine	E. coli
	BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokin...
TMPY-03038	CD157 Protein, Rat, Recombinant (His)	Rat	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-00614	BMPR1A/ALK-3 Protein, Canine, Recombinant (hFc)	Canine	HEK293
	Activin receptor-Like Kinase 3 (ALK-3), also known as Bone Morphogenetic Protein Receptor, type IA (BMPR1A), is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the transforming growth factor beta...
TMPY-03037	CD157 Protein, Rat, Recombinant (hFc)	Rat	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPH-01014	BMP-2 Protein, Human, Recombinant (His)	Human	E. coli
	Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including cardiogenesis, neurogenesis, and osteogenesis. Induces cartilage and bone formation. Initiates the canonical...
TMPY-00968	CD157 Protein, Human, Recombinant (His)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPH-01015	BMP-3 Protein, Human, Recombinant (His)	Human	E. coli
	Growth factor of the TGF-beta superfamily that plays an essential role in developmental process by inducing and patterning early skeletal formation and by negatively regulating bone density. Antagonizes the ability of ce...
TMPJ-00445	IBSP Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Bone sialoprotein 2(IBSP) is a monomeric non‑collagenous member of the SIBLING family of extracellular matrix proteins. It is principally associated with the early stages of bone mineralization. Mouse IBSP is synthesize...
TMPH-01017	BMP-4 Protein, Human, Recombinant (His)	Human	E. coli
	Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis. Acts in concert with PTHLH/PTHRP to stimu...
TMPJ-00924	Decorin Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Decorin, also known as PG40 and DCN, is a member of the class I family of small leucine-rich proteoglycans (SLRPs) that is expressed in the stroma of various forms of cancer and has been recently proposed to act as a gua...
TMPH-00228	BMP-4 Protein, Bovine, Recombinant (GST)	Bovine	E. coli
	Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis. Acts in concert with PTHLH/PTHRP to stimu...
TMPY-03193	BST2 Protein, Human, Recombinant (hFc)	Human	HEK293
	BST2 was frequently overexpressed in GC tissues compared with the adjacent non-tumorous tissues, and high BST2 expression was correlated with tumor stage and lymphatic metastasis. Furthermore, in vitro experiments demons...
TMPH-02552	BMP3 Protein, Mouse, Recombinant (Myc)	Mouse	E. coli
	Negatively regulates bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification.
TMPH-00264	Decorin Protein, Bovine, Recombinant (His)	Bovine	E. coli
	May affect the rate of fibrils formation.
TMPY-00431	BMP-4 Protein, Mouse, Recombinant (rFc)	Mouse	HEK293
	BMP4 (bone morphogenetic protein-4)-directed differentiation of human embryonic stem cells (ESCd). Autophagy is a conserved catabolic process with complicated roles in tumor development. Bone morphogenetic protein 4 (BMP...
TMPY-04367	BMPRIB Protein, Human, Recombinant (aa 149-502, His & GST)	Human	Baculovirus-Insect Cells
	BMPR1B(bone morphogenetic protein receptor, type IB), also known as ALK6, is a member of the bone morphogenetic protein (BMP) receptor family. BMPs are involved in endochondral bone formation and embryogenesis. These pro...
TMPY-03362	BMPRIB Protein, Human, Recombinant (hFc)	Human	HEK293
	BMPR1B(bone morphogenetic protein receptor, type IB), also known as ALK6, is a member of the bone morphogenetic protein (BMP) receptor family. BMPs are involved in endochondral bone formation and embryogenesis. These pro...
TMPH-02548	Biglycan Protein, Mouse, Recombinant (His)	Mouse	E. coli
	May be involved in collagen fiber assembly.
TMPY-00594	Alkaline Phosphatase/ALPL Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Alkaline phosphatase (ALPL) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. The process of removing the phosphate group is cal...
TMPY-00446	Alkaline Phosphatase/ALPL Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Alkaline phosphatase (ALPL) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. The process of removing the phosphate group is cal...
TMPY-01764	BMPR1A/ALK-3 Protein, Human, Recombinant (His)	Human	HEK293
	Activin receptor-Like Kinase 3 (ALK-3), also known as Bone Morphogenetic Protein Receptor, type IA (BMPR1A), is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the transforming growth factor beta...
TMPY-00962	BMPR1A/ALK-3 Protein, Mouse, Recombinant (His & hFc)	Mouse	HEK293
	Activin receptor-Like Kinase 3 (ALK-3), also known as Bone Morphogenetic Protein Receptor, type IA (BMPR1A), is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the transforming growth factor beta...
TMPY-01374	BMPR1A/ALK-3 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Activin receptor-Like Kinase 3 (ALK-3), also known as Bone Morphogenetic Protein Receptor, type IA (BMPR1A), is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the transforming growth factor beta...
TMPY-05485	BMPR1A/ALK-3 Protein, Human, Recombinant (hFc)	Human	HEK293
	Activin receptor-Like Kinase 3 (ALK-3), also known as Bone Morphogenetic Protein Receptor, type IA (BMPR1A), is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the transforming growth factor beta...
TMPJ-00713	GDF-11 Protein, Human, Recombinant	Human	Human Cells
	Growth/differentiation factor 11(GDF-11) is a secreted protein, which belongs to the transforming growth factor beta superfamily. GDF-11 controls anterior-posterior patterning by regulating the expression of Hox genes. ...
TMPY-04742	BST2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	BST2 was frequently overexpressed in GC tissues compared with the adjacent non-tumorous tissues, and high BST2 expression was correlated with tumor stage and lymphatic metastasis. Furthermore, in vitro experiments demons...
TMPH-01019	BMP-7 Protein, Human, Recombinant (GST)	Human	E. coli
	Growth factor of the TGF-beta superfamily that plays important role in various biological processes, including embryogenesis, hematopoiesis, neurogenesis and skeletal morphogenesis. Initiates the canonical BMP signaling ...
TMPY-01178	CD157 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPH-01013	BMP-15 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth.
TMPJ-01473	BMP-7 Protein, Human, Recombinant	Human	Human Cells
	Bone morphogenetic protein 7 (BMP7), also known as osteogenic protein-1 (OP-1) is a member of Transforming growth factor-β (TGF-β) family of proteins. Bone morphogenetic proteins were discovered in 1965 by Marshal Urist,...
TMPY-02674	BST2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	BST2 was frequently overexpressed in GC tissues compared with the adjacent non-tumorous tissues, and high BST2 expression was correlated with tumor stage and lymphatic metastasis. Furthermore, in vitro experiments demons...
TMPK-00538	Osteopontin Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Ovarian cancer is one of the most lethal malignant tumors in women. Secreted phosphoprotein 1 (SPP1) plays an important role in some cancer types. The expression of SPP1 was higher in epithelial ovarian cancer tissues th...
TMPK-00807	Osteopontin Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Secreted phosphoprotein 1 (SPP1) expression in TAMs isolated from lung adenocarcinoma tissues and PMA-treated THP-1 cells were measured. Macrophage polarization was identified by flow cytometric analysis. Cell migration ...
TMPH-01012	BMP-1 Protein, Human, Recombinant (His)	Human	E. coli
	Metalloprotease that plays key roles in regulating the formation of the extracellular matrix (ECM) via processing of various precursor proteins into mature functional enzymes or structural proteins. Thereby participates ...
TMPK-00676	Osteopontin Protein, Human, Recombinant (aa 17-300, His)	Human	HEK293
	Ovarian cancer is one of the most lethal malignant tumors in women. Secreted phosphoprotein 1 (SPP1) plays an important role in some cancer types. The expression of SPP1 was higher in epithelial ovarian cancer tissues th...
TMPH-01018	BMP-6 Protein, Human, Recombinant (His)	Human	E. coli
	Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes including cartilage and bone formation. Plays also an important role in the regulation of iron metabolism by acting as ...
TMPH-01773	ELANE Protein, Human, Recombinant (GST)	Human	E. coli
	Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis. Capable of killing E.coli but not S.aureus in vitro; digests outer membrane pro...
TMPJ-00476	BMPG Protein, Human, Recombinant (His)	Human	Human Cells
	Bone Marrow Proteoglycan (BMPG) is a secreted protein that contains one C-type lectin domain. BMPG is the predominant constituent of the crystalline core of the eosinophil granule. BMPG is highly expressed in placenta an...
TMPY-04496	BMPRIB Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	BMPR1B(bone morphogenetic protein receptor, type IB), also known as ALK6, is a member of the bone morphogenetic protein (BMP) receptor family. BMPs are involved in endochondral bone formation and embryogenesis. These pro...
TMPY-00683	BMPR2 Protein, Human, Recombinant (His & hFc)	Human	HEK293
	The bone morphogenetic protein type II receptor (BMPR-II, or BMPR2), a receptor for the transforming growth factor (TGF)-beta/bone morphogenetic protein (BMP) superfamily. Reduced expression or function of BMPR2 signalin...
TMPJ-00202	CD157 Protein, Human, Recombinant (hFc)	Human	Human Cells
	The cluster of differentiation (CD) system is a glycosyl phosphatidylinositol anchored membrane protein that belongs to the CD38 family.It is generally used in immunophynotyping. CD157 was discovered in a bone marrow str...
TMPJ-00325	BMPR1A/ALK-3 Protein, Human, Recombinant (hFc & His)	Human	Human Cells
	Bone Morphogenetic Protein Receptor Type-1A (BMPR1A) belongs to the TKL Ser/Thr protein kinase family and TGFB receptor subfamily, including the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. BMPR1A i...
TMPJ-00966	GDF-5 Protein, Human, Recombinant	Human	E. coli
	Growth Differentiation Factor 5(GDF-5, BMP-14) is a member of the BMP family of TGFβ superfamily proteins. Human GDF-5, -6, and -7 are a defined subgroup of the BMP family. GDF-5 is synthesized as a homodimeric precursor...
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BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc)

TMPY-00680

Species: Human,Mouse,Rat,Rhesus,Canine

Expression System: HEK293

BST2 Protein, Human, Recombinant (His)

TMPY-03235

Species: Human

Expression System: HEK293

BMP-4 Protein, Human, Recombinant (E399D)

TMPY-06842

Species: Human

Expression System: E. coli

Alkaline Phosphatase/ALPL Protein, Human, Recombinant (His)

TMPY-00663

Species: Human

Expression System: HEK293

BMPR2 Protein, Human, Recombinant (His)

TMPY-01059

Species: Human

Expression System: HEK293

BMP-2 Protein, Danio rerio (zebrafish), Recombinant

TMPY-03297

Species: Danio rerio (zebrafish)

Expression System: E. coli

BMP-5 Protein, Human, Recombinant (hFc)

TMPY-00681

Species: Human

Expression System: HEK293

BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant

TMPY-01136

Species: Human,Mouse,Rat,Rhesus,Canine

Expression System: E. coli

CD157 Protein, Rat, Recombinant (His)

TMPY-03038

Species: Rat

Expression System: HEK293

BMPR1A/ALK-3 Protein, Canine, Recombinant (hFc)

TMPY-00614

Species: Canine

Expression System: HEK293

CD157 Protein, Rat, Recombinant (hFc)

TMPY-03037

Species: Rat

Expression System: HEK293

BMP-2 Protein, Human, Recombinant (His)

TMPH-01014

Species: Human

Expression System: E. coli

CD157 Protein, Human, Recombinant (His)

TMPY-00968

Species: Human

Expression System: HEK293

BMP-3 Protein, Human, Recombinant (His)

TMPH-01015

Species: Human

Expression System: E. coli

IBSP Protein, Mouse, Recombinant (His)

TMPJ-00445

Species: Mouse

Expression System: Human Cells

BMP-4 Protein, Human, Recombinant (His)

TMPH-01017

Species: Human

Expression System: E. coli

Decorin Protein, Mouse, Recombinant (His)

TMPJ-00924

Species: Mouse

Expression System: Human Cells

BMP-4 Protein, Bovine, Recombinant (GST)

TMPH-00228

Species: Bovine

Expression System: E. coli

BST2 Protein, Human, Recombinant (hFc)

TMPY-03193

Species: Human

Expression System: HEK293

BMP3 Protein, Mouse, Recombinant (Myc)

TMPH-02552

Species: Mouse

Expression System: E. coli

Decorin Protein, Bovine, Recombinant (His)

TMPH-00264

Species: Bovine

Expression System: E. coli

BMP-4 Protein, Mouse, Recombinant (rFc)

TMPY-00431

Species: Mouse

Expression System: HEK293

BMPRIB Protein, Human, Recombinant (aa 149-502, His & GST)

TMPY-04367

Species: Human

Expression System: Baculovirus-Insect Cells

BMPRIB Protein, Human, Recombinant (hFc)

TMPY-03362

Species: Human

Expression System: HEK293

Biglycan Protein, Mouse, Recombinant (His)

TMPH-02548

Species: Mouse

Expression System: E. coli

Alkaline Phosphatase/ALPL Protein, Mouse, Recombinant (hFc)

TMPY-00594

Species: Mouse

Expression System: HEK293

Alkaline Phosphatase/ALPL Protein, Mouse, Recombinant (His)

TMPY-00446

Species: Mouse

Expression System: HEK293

BMPR1A/ALK-3 Protein, Human, Recombinant (His)

TMPY-01764

Species: Human

Expression System: HEK293

BMPR1A/ALK-3 Protein, Mouse, Recombinant (His & hFc)

TMPY-00962

Species: Mouse

Expression System: HEK293

BMPR1A/ALK-3 Protein, Mouse, Recombinant (His)

TMPY-01374

Species: Mouse

Expression System: HEK293

BMPR1A/ALK-3 Protein, Human, Recombinant (hFc)

TMPY-05485

Species: Human

Expression System: HEK293

GDF-11 Protein, Human, Recombinant

TMPJ-00713

Species: Human

Expression System: Human Cells

BST2 Protein, Mouse, Recombinant (His)

TMPY-04742

Species: Mouse

Expression System: HEK293

BMP-7 Protein, Human, Recombinant (GST)

TMPH-01019

Species: Human

Expression System: E. coli

CD157 Protein, Mouse, Recombinant (His)

TMPY-01178

Species: Mouse

Expression System: HEK293

BMP-15 Protein, Human, Recombinant (His & Myc)

TMPH-01013

Species: Human

Expression System: E. coli

BMP-7 Protein, Human, Recombinant

TMPJ-01473

Species: Human

Expression System: Human Cells

BST2 Protein, Mouse, Recombinant (hFc)

TMPY-02674

Species: Mouse

Expression System: HEK293

Osteopontin Protein, Cynomolgus, Recombinant (His)

TMPK-00538

Species: Cynomolgus

Expression System: HEK293

Osteopontin Protein, Mouse, Recombinant (His)

TMPK-00807

Species: Mouse

Expression System: HEK293

BMP-1 Protein, Human, Recombinant (His)

TMPH-01012

Species: Human

Expression System: E. coli

Osteopontin Protein, Human, Recombinant (aa 17-300, His)

TMPK-00676

Species: Human

Expression System: HEK293

BMP-6 Protein, Human, Recombinant (His)

TMPH-01018

Species: Human

Expression System: E. coli

ELANE Protein, Human, Recombinant (GST)

TMPH-01773

Species: Human

Expression System: E. coli

BMPG Protein, Human, Recombinant (His)

TMPJ-00476

Species: Human

Expression System: Human Cells

BMPRIB Protein, Mouse, Recombinant (hFc)

TMPY-04496

Species: Mouse

Expression System: HEK293

BMPR2 Protein, Human, Recombinant (His & hFc)

TMPY-00683

Species: Human

Expression System: HEK293

CD157 Protein, Human, Recombinant (hFc)

TMPJ-00202

Species: Human

Expression System: Human Cells

BMPR1A/ALK-3 Protein, Human, Recombinant (hFc & His)

TMPJ-00325

Species: Human

Expression System: Human Cells

GDF-5 Protein, Human, Recombinant

TMPJ-00966

Species: Human

Expression System: E. coli

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カタログ番号	製品名
L7900	Osteogenesis Compound Library	317 compounds
	A unique collection of 317 osteogenesis related compounds for high throughput and high content screening;
L8400	Hematonosis Compound Library	514 compounds
	A unique collection of 514 compounds related to hematologic diseases for high throughput screening (HTS) and high content screening (HCS);
L9810	Anti-Fibrosis Compound Library	1155 compounds
	A unique collection of 1155 potential anti-fibrosis compounds, can be used in HTS and HCS;
L6230	Miao medicine Compound Library	534 compounds
	A unique collection of 534 compounds featuring natural product molecules derived from Miao medicine that can be used for high-throughput and high-content screening.
L8000	Stem Cell Differentiation Compound Library	1197 compounds
	A unique collection of 1197 stem cell differentiation signaling targeted compounds for high throughput and high content screening;

ライブラリー

Osteogenesis Compound Library

L7900

Compounds: 317

Hematonosis Compound Library

L8400

Compounds: 514

Anti-Fibrosis Compound Library

L9810

Compounds: 1155

Miao medicine Compound Library

L6230

Compounds: 534

Stem Cell Differentiation Compound Library

L8000

Compounds: 1197