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天然化合物

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カタログ番号	製品名	別名	ターゲット
T17258	WRG-28		Discoidin Domain Receptor (DDR)
	WRG-28 is a potent and selective, allosteric discoidin domain receptor 2 (ddr2) inhibitor(IC50 : 230 nM)		Discoidin Domain Receptor (DDR)
T21806	HNHA		HDAC
	HNHA is an inhibitor of HDAC.		HDAC
T9720	T3Inh-1		Others
	T3Inh-1 is an effective and selective inhibitor of ppGalNAc-T3 with an IC50 of 7 µM. T3Inh-1 prevents breast cancer cells. T3Inh-1 reduces FGF23 hormone levels in both tissue cells and mice, without causing any toxic sid...		Others
T10904	CWP232228		Wnt/beta-catenin
	CWP232228, a potent and selective Wnt / β-catenin signaling inhibitor, antagonizes the binding of β-catenin to T-cell factor (TCF) in the nucleus. CWP232228 inhibits the formation and metastasis of tumors by inhibiting t...		Wnt/beta-catenin
T2345	PTC-209	PTC209,PTC 209	BMI-1 , Autophagy
	PTC-209 is a potent and selective BMI-1 inhibitor.		BMI-1 , Autophagy
T19723	AMTB hydrochloride	AMTB	TRP/TRPV Channel
	AMTB hydrochloride (AMTB HCl) is a novel TRPM8 channel blocker and is effective for pain and urinary diseases. AMTB can act on the bladder afferent pathway to attenuate the bladder micturition reflex and nociceptive refl...		TRP/TRPV Channel
T1394	Ibuprofen	Brufen,(±)-Ibuprofe,Motrin,Advil	COX
	Ibuprofen (Advil) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resu...		COX
T6540	Ibuprofen Lysine	Neoprofen	COX
	Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug.		COX
T15249	Estrogen receptor modulator 1		Estrogen Receptor/ERR
	Estrogen receptor modulator 1 causes regression of Tamoxifen-resistant, hormone-independent xenograft tumors. Estrogen receptor modulator 1 is an orally active and selective estrogen receptor modulator (SERM) (pIC50: 0.4...		Estrogen Receptor/ERR
T6588	Mitoxantrone	mitozantrone	Topoisomerase , PKC
	Mitoxantrone (mitozantrone) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisome...		Topoisomerase , PKC
T9756	AZD-9574		PARP
	AZD-9574 is a selective inhibitor of PARP1 at the sites of SSBs. AZD-9574 exhibits anti-cancer activities and can be used in studies about HRD+ breast cancer and advanced solid malignancies.		PARP
T2085	PQ401	IGF-1R Inhibitor II	Apoptosis , IGF-1R
	PQ401 (IGF-1R Inhibitor II) suppresses autophosphorylation of IGF-1R domain(IC50<1 μM).		Apoptosis , IGF-1R
T0158	Mitoxantrone dihydrochloride	Mitoxantrone 2HCl,Mitoxantrone hydrochloride,NSC-301739,mitozantrone dihydrochloride	Topoisomerase , PKC
	Mitoxantrone dihydrochloride (NSC-301739) is the hydrochloride salt of an anthracenedione antibiotic with antineoplastic activity. It is a type II topoisomerase inhibitor.		Topoisomerase , PKC
T0640	Benzyl butyl phthalate	BBP,1,2-benzenedicarboxylic acid,butyl phenylmethyl ester,Butyl benzyl phthalate	Others , Aryl Hydrocarbon Receptor
	Benzyl butyl phthalate (1,2-benzenedicarboxylic acid) is used as a plasticizer for PVC.		Others , Aryl Hydrocarbon Receptor
T6178	PTC-209 hydrobromide	PTC-209 HBr	BMI-1 , Autophagy
	PTC-209 hydrobromide (PTC-209 HBr) is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in irreversible reduction of cancer-initiating cells (CICs).		BMI-1 , Autophagy
T4399	ML239	CID-49843203	Others
	ML239 (CID-49843203) is a potent and selective inhibitor of breast cancer stem cells, with an IC50 of 1.16 μM.		Others
T13688	Eribulin	B1939,ER-086526,E7389	Others
	Eribulin inhibits the proliferation of cancer cells by binding microtubule proteins and microtubules. Eribulin is a microtubule targeting agent that is used in the treatment of metastatic breast cancer.		Others
T12344L1	OTS186935 FA	OTS186935 FA（2093400-18-9 Free base）	Histone Methyltransferase
	OTS186935 FA is a protein methyltransferase SUV39H2 inhibitor.OTS186935 FA inhibits tumor growth in MDA-MB-231 breast cancer cells and A549 lung cancer cells.		Histone Methyltransferase
T7018	WZB117		transporter
	WZB117 is a Glucose Transporter 1 (GLUT1) inhibitor. when IC50 of WZB117 approximate 10 μM, it inhibits lung cancer A549 cells and breast cancer MCF7 cells proliferation.		transporter
T9468	FR054		Others
	FR054 is an inhibitor of the Hexosamine Biosynthetic Pathway (HBP) enzyme PGM3, with a remarkable anti-breast cancer effect. FR054 induces in different breast cancer cells a dramatic decrease in cell proliferation and su...		Others
T17255	WJ460		Others
	WJ460 is an effective inhibitor of myoferlin. WJ460 exerts anti-metastatic activity in breast cancer cells.		Others
T9996	NCT-58	NCT58	HSP
	NCT-58 is a potent C-terminal HSP90 inhibitor. NCT-58 does not induce the heat shock response (HSR). NCT-58 elicits anti-tumor activity via the simultaneous downregulation of HER family members as well as inhibition of ...		HSP
T77732L	HFY-4A HCL (2094810-82-7 Free base)
	HFY-4A HCL is a novel HDAC inhibitor.HFY-4A HCL has antitumour activity and has shown antiproliferative activity in breast cancer cells.
T14685	BMS-986158		Epigenetic Reader Domain
	BMS-986158 is a highly effective BET inhibitor, demonstrating IC50 values of 6.6 nM in NCI-H211 small cell lung cancer (SCLC) cells and 5 nM in MDA-MB231 triple negative breast cancer (TNBC) cells.		Epigenetic Reader Domain
T10325	ANI-7		Chk
	ANI-7 is an activator of aryl hydrocarbon receptor (AhR) pathway. ANI-7 inhibits the growth of multiple cancer cells and potently and selectively inhibits the growth of MCF-7 breast cancer cells (GI50: 0.56 μM).		Chk
T37518	Diphenyl disulfide	Phenyl disulfide	Apoptosis , BCL , Endogenous Metabolite
	Diphenyl disulfide (Phenyl disulfide) shows anticancer activity in breast cancer cell lines.Diphenyl disulfide induces and enhances apoptosis in breast cancer cells through Bax protein hydrolysis activation and concomita...		Apoptosis , BCL , Endogenous Metabolite
T12454	PI-273		Apoptosis , PI4K
	PI-273, a Substrate-Competitive, Specific Small-Molecule Inhibitor of PI4KIIα, Inhibits the Growth of Breast Cancer Cells		Apoptosis , PI4K
T8973	HS-1793		Others
	HS-1793, a resveratrol analogue, downregulates the expression of hypoxia-induced HIF-1 and VEGF and inhibits tumor growth of human breast cancer cells in a nude mouse xenograft model		Others
T73552	BPDA2		Phosphatase
	BPDA2 is a selective and potent SHP2 inhibitor with IC50 values of 92.0 nM, 33.39 μM, and 40.71 μM for SHP2, SHP1, and SHP1B, respectively.DBDA2 possesses anticancer and antitumor activity and inhibits anchorage-independ...		Phosphatase
T10165L	5-A-RU hydrochloride	5-Amino-6-(D-ribitylamino)uracil hydrochloride	Others
	5-A-RU hydrochloride (5-Amino-6-(D-ribitylamino)uracil hydrochloride) is an intermediate of bacterial riboflavin that activates mucosal-associated invariant T cells (MAIT).5-A-RU is used in the study of breast and prosta...		Others
T83636L	NSC 122393	3,4,5,6-Tetrabromofluorescein
	NSC 122393 is a fluorescent dye that inhibits the interaction between Bax and Bcl-X and induces apoptosis in Bcl-X overexpressing breast cancer cells.
T8569	DMH-25		mTOR
	DMH25 is a novel covalent and potent inhibitor of mTOR and shows in vivo antitumor activity against triple-negative breast cancer cells.		mTOR
T16991	Targapremir-210	TGP-210	Apoptosis
			Apoptosis
T64348	Antiproliferative agent-16	Antiproliferative agent-16	Others
	Antiproliferative agent-16 (Antiproliferative agent-16) is an indolyl hydrazide-hydrazone compound with anticancer activity. Antiproliferative agent-16 exhibits specificity toward breast cancer cells (IC50 of 6.94 μM for...		Others
T24166	Inecalcitol	TX 522,TX-522,TX522	Apoptosis
	Inecalcitol (TX 522) is the growth inhibitor of human breast cancer cells. Inecalcitol is a unique vitamin D3 analog with Kd of 0.53 nM.		Apoptosis
T9521	CHR-6494 TFA		Others
	CHR-6494 TFA is a potent haspin inhibitor, with an IC50 of 2 nM. It inhibits histone H3T3 phosphorylation. CHR-6494 TFA induces the apoptosis of cancer cells, including melanoma and breast cancer. CHR-6494 TFA can be use...		Others
T28543	RK-9123016	RK9123016,RK 9123016	Sirtuin
	RK-9123016 is a SIRT2 inhibitor. RK-9123016 increases the acetylation level of eukaryotic translation initiation factor 5A (eIF5A), a physiological substrate of SIRT2, and reduces cell viability of human breast cancer ce...		Sirtuin
T4022	QS11	QS 11	GTPase
	QS11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. Modulates ARF-GTP levels and synergizes with the Wnt/β-catenin signaling pathway to upregulate β-catenin nuclear translocation. Also r...		GTPase
T35528L	TD52 dihydrochloride	TD52 dihydrochloride(1798328-24-1 Free base),TD52 2HCl	Others
	TD52 dihydrochloride (TD52 2HCl), a derivative of Erlotinib, is a potent and orally active inhibitor of protein phosphatase 2A (CIP2A). It exhibits strong anti-cancer properties by regulating the CIP2A/PP2A/p-Akt signali...		Others
T13687	Eribulin mesylate	B1939 mesylate,ER-086526 mesylate,E7389 mesylate	Apoptosis , Others , Microtubule Associated
	Eribulin mesylate (E7389 mesylate) (E7389 mesylate) inhibits the proliferation of cancer cells by binding microtubule proteins and microtubules. Eribulin mesylate (E7389 mesylate) is a microtubule targeting agent that is...		Apoptosis , Others , Microtubule Associated
T60753	L82		DNA
	L82 is a DNA ligase 1 (DNA Lig1) inhibitor (hLig1 IC50=12 μM) that is selective and non-competitive.L82 expresses anti-proliferative activity against breast cancer cells.		DNA
T8984	FLTX1		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
	FLTX1 is a fluorescent derivative of Tamoxifen, designed to efficiently target and label intracellular Tamoxifen-binding sites (estrogen receptors) both under permeabilized and non-permeabilized conditions. Additionally,...		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
T72528	NSC243928 mesylate		HuR
	NSC243928 mesylate binds to human lymphocyte antigen 6 (LY6), a cell growth inhibitor with anticancer activity, and induces cell death in triple-negative breast cancer cells in a LY6K-dependent manner.		HuR
T8325	SR-4835		Apoptosis , CDK
	SR-4835 is a highly selective dual inhibitor of CDK12 and CDK13(CDK12: IC50=99 nM, Kd=98 nM; CDK13: Kd=4.9 nM), which disables triple-negative breast cancer (TNBC) cells		Apoptosis , CDK
T16436	PBOX 6	PBOX-6	Apoptosis
	PBOX 6 is a pyrrolo-1,5-benzoxazepine (PBOX) compound with anticancer and antitumor activity that inhibits breast cancer cell growth in vitro and selectively induces apoptosis in leukemia cells via c-Jun NH2 terminal kin...		Apoptosis
T41233	Cis-22a		Calcium Channel , TRP/TRPV Channel
	Cis-22a is a TRPV6 inhibitor (IC50 = 0.32 μM), which exhibits selectivity against related TRPV channels and calcium channels. cis-22a displays antiproliferative effects on T47D human breast cancer cells.		Calcium Channel , TRP/TRPV Channel
T36970	STD1T		DUB
	STD1T is a selective and potent inhibitor of the deubiquitinase USP2a with potential anticancer activity that reduces cell cycle protein D1 protein levels in HCT116 colon and MCF-7 breast cancer cells.		DUB
T9320	YK-3-237	B-[2-Methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]boronic acid	Sirtuin
	YK-3-237 (B-[2-Methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]boronic acid) reduces acetylation of mtp53 and exhibits anti-proliferative effects toward triple-negative breast cancer (TNBC) cells ca...		Sirtuin
T22646	CFM 4	CFM-4,CFM4	Apoptosis , APC
	CFM 4 is a potent small molecule CARP-1/APC-2 antagonist that prevents CARP-1 from binding to APC-2, contributes to G2M cell cycle arrest, and induces apoptosis, with an IC50 in the range of 10-15 μM.CFM 4 inhibits the g...		Apoptosis , APC
T77701	FL118	FL 118,FL-118,10,11-(Methylenedioxy)-20(S)-camptothecin	Survivin
	FL118 is a novel survivin inhibitor that inhibits cancer stem cell-like properties.FL118 is a novel camptothecin analog with anticancer activity that inhibits epithelial-mesenchymal transition through the Wnt/β-catenin s...		Survivin

Compounds

WRG-28

T17258

Synonym:

Target: Discoidin Domain Receptor (DDR)

Target: Wnt/beta-catenin

PTC-209

T2345

Synonym: PTC209,PTC 209

Target: BMI-1, Autophagy

AMTB hydrochloride

T19723

Synonym: AMTB

Target: TRP/TRPV Channel

Ibuprofen

T1394

Synonym: Brufen,(±)-Ibuprofe,Motrin,Advil

Estrogen receptor modulator 1

T15249

Synonym:

Target: Estrogen Receptor/ERR

Mitoxantrone

T6588

Synonym: mitozantrone

Target: Topoisomerase, PKC

Synonym: IGF-1R Inhibitor II

Target: Apoptosis, IGF-1R

Mitoxantrone dihydrochloride

T0158

Synonym: Mitoxantrone 2HCl,Mitoxantrone hydrochloride,NSC-301739,mitozantrone dihydrochloride

Target: Topoisomerase, PKC

Benzyl butyl phthalate

T0640

Synonym: BBP,1,2-benzenedicarboxylic acid,butyl phenylmethyl ester,Butyl benzyl phthalate

Target: Others, Aryl Hydrocarbon Receptor

PTC-209 hydrobromide

T6178

Synonym: PTC-209 HBr

Target: BMI-1, Autophagy

ML239

T4399

Synonym: CID-49843203

Target: Others

Eribulin

T13688

Synonym: B1939,ER-086526,E7389

Target: Others

OTS186935 FA

T12344L1

Synonym: OTS186935 FA（2093400-18-9 Free base）

Target: Histone Methyltransferase

HFY-4A HCL (2094810-82-7 Free base)

Target: Epigenetic Reader Domain

Synonym: Phenyl disulfide

Target: Apoptosis, BCL, Endogenous Metabolite

PI-273

T12454

Synonym:

Target: Apoptosis, PI4K

Synonym: 5-Amino-6-(D-ribitylamino)uracil hydrochloride

Target: Others

NSC 122393

T83636L

Synonym: 3,4,5,6-Tetrabromofluorescein

Antiproliferative agent-16

T64348

Synonym: Antiproliferative agent-16

Target: Others

Inecalcitol

T24166

Synonym: TX 522,TX-522,TX522

Synonym: RK9123016,RK 9123016

Synonym: TD52 dihydrochloride(1798328-24-1 Free base),TD52 2HCl

Target: Others

Eribulin mesylate

T13687

Synonym: B1939 mesylate,ER-086526 mesylate,E7389 mesylate

Target: Apoptosis, Others, Microtubule Associated

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

Target: Apoptosis, CDK

Target: Calcium Channel, TRP/TRPV Channel

Synonym: B-[2-Methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]boronic acid

Target: Apoptosis, APC

FL118

T77701

Synonym: FL 118,FL-118,10,11-(Methylenedioxy)-20(S)-camptothecin

Target: Survivin

カタログ番号	製品名	別名	ターゲット
T5724	Neogambogic acid	neo-gambogic acid	Apoptosis , Others , Antibacterial
	Neogambogic acid, an active ingredient in garcinia, can inhibit the growth of some solid tumors and result in an anticancer effect, it may be responsible for the inhibition of proliferation of human breast cancer cell li...		Apoptosis , Others , Antibacterial
TN2883	3',4'-Dimethoxyflavone		Others , PARP
	3',4'-Dimethoxyflavone is a standard compound of flavonoids with numerous medicinal activities.		Others , PARP
T36857	Estrone sulfate sodium	Estrone 3-sulfate (sodium salt),17β-Estrone 3-sulfate	Endogenous Metabolite
	Estrone sulfate sodium (17β-Estrone 3-sulfate) is an endogenous steroid and an estrogen ester that is biologically inactive. It is converted by steroid sulfatase into estrone . Estrone sulfate sodium has been investigate...		Endogenous Metabolite
T2882	Genistin	Genistoside,Genistein glucoside,Genistein 7-glucoside,Genistine,Genistein 7-O-β-D-glucopyranoside	Apoptosis , Estrogen Receptor/ERR , Others
	Genistin (Genistoside) is the major isoflavonoid of soybeans and soy products.It has been reported to possess various therapeutic effects, including anti-inflammatory and anticancer activities		Apoptosis , Estrogen Receptor/ERR , Others
TN3150	6,8-Diprenylnaringenin	Senegalensin,Lonchocarpol A	BCRP , ABC
			BCRP , ABC
TN1768	Iriflophenone		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
	Iriflophenone stimulates cells proliferation in MCF-7 and T-47D human breast cancer.		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
T3916	Ginsenoside F2		Apoptosis , Endogenous Metabolite , Autophagy
	Ginsenoside F2 has antiproliferative activity against breast cancer stem cells (CSCs). It induces apoptosis in breast CSCs by activating the intrinsic apoptotic pathway and mitochondrial dysfunction.		Apoptosis , Endogenous Metabolite , Autophagy
T3729	Ethyl gallate	Nipagallin A,Phyllemblin,gallic acid ethyl ester	MMP , NF-κB , Akt , Antibacterial
	Ethyl gallate (gallic acid ethyl ester) obviously decreases cell proliferation in MDA-MB-231 and MCF-7 cells in a dose- and time-dependent manner, exhibits cytotoxicity in a dose-dependent manner. Ethyl gallate can inhib...		MMP , NF-κB , Akt , Antibacterial
T36430	Pheophorbide a
	Pheophorbide a is a product of chlorophyll breakdown that has been used as a photosensitizer in photodynamic therapy for the treatment of cancer. It has been reported to inhibit U87MG cells with an IC50 value of 2.8 μg/m...
T7990	9-hydroxy-4-androstene-3,17-dione		Others
	9-hydroxy-4-androstene-3,17-dione is a steroid hormone. It has anti-tumor activity and can inhibit the growth of many types of cancer cells, including breast, prostate and lung cancer cells.		Others
TQ0089	Juglanin		Apoptosis , JNK , Autophagy
	Juglanin is a JNK activator. Juglanin with inflammation and anti-tumor activities. It can induce apoptosis and autophagy on human breast cancer cells.		Apoptosis , JNK , Autophagy
TN2269	Tetramethylcurcumin		Apoptosis , STAT
	Tetramethylcurcumin is a novel curcumin analog, is an effective inhibitors of STAT3 phosphorylation, DNA binding activity, and transactivation in vitro.it also inhibits colony formation in soft agar, cell invasion, and e...		Apoptosis , STAT
T6S2038	Ziyuglycoside II		Apoptosis , Antioxidant , Reactive Oxygen Species
	1. Ziyuglycoside II has anti-inflammation and antioxidation properties. 2. Ziyuglycoside II has antibiosis, and homeostasis properties. 3. Ziyuglycoside II has anticancer, and antitumor properties against gastric cancer ...		Apoptosis , Antioxidant , Reactive Oxygen Species
T5793	Britannin		Apoptosis , AMPK , Autophagy
	Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells.		Apoptosis , AMPK , Autophagy
T83321	4-Demethyldeoxypodophyllotoxin		Chk
	4-Demethyldeoxypodophyllotoxin, an aryl tetrahydronaphthalenyl lignan analog from the roots of Podophyllum peltatum, has anticancer activity and modulates the Chk-2 signaling pathway in MCF-7 breast cancer cells.		Chk
T5S0689	Demethylwedelolactone		Serine Protease
	Demethylwedelolactone is a natural product isolated from Eclipta alba, has trypsin inhibitory effect an IC50 of 3.0 μM. it exerts anti-invasive growth effect on breast cancer cells.		Serine Protease
T7982	3,6-Dihydroxyflavone		Others
	3,6-Dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway.		Others
TN1222	26-Deoxyactein	27-Deoxyactein,23-epi-26-Deoxyactein	NOS , CDK , NO Synthase
	23-epi-26-Deoxyactein (27-Deoxyactein) has anti-inflammatory activity, it inhibits nitric oxide production by reducing iNOS expression without affecting activity of the enzyme. It also has anti-cancer activity, it can in...		NOS , CDK , NO Synthase
T7979	2-Hydroxychalcone	2-(2-Hydroxybenzal)Acetophenone	Apoptosis , BCL , Others , NF-κB
	2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated.It can inhibit invasion of triple negative breast cancer cells.		Apoptosis , BCL , Others , NF-κB
T6S1683	Demethoxycurcumin	Curcumin II,Desmethoxycurcumin,Monodemethoxycurcumin	Apoptosis , Antioxidant , Antibacterial , Autophagy
	1. Demethoxycurcumin (Desmethoxycurcumin) has antioxidant activity. 2. Demethoxycurcumin has anti-inflammatory activity. 3. Demethoxycurcumin has anti-proliferative activity. 4. Demethoxycurcumin has anti-acanthamoebic e...		Apoptosis , Antioxidant , Antibacterial , Autophagy
T5S1331	Herbacetin		c-Met/HGFR , Akt
	1. Herbacetin induces apoptosis in HepG2 cells, by ROS and PI3K/Akt pathway. 2. Herbacetin suppresses the HGF-induced motility of human breast cancer MDA-MB-231 cells by inhibiting c-Met and Akt phosphorylation.		c-Met/HGFR , Akt
T5S0761	Nitidine chloride		Apoptosis , ERK , FAK , p38 MAPK , NF-κB , Topoisomerase , STAT , Parasite
	1. Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. 2. Nitidine chloride inhibits the proliferation of SMMC-7721 cells in vitro in a time- and dose-dependent manner and id...
T1660	Silibinin	Silibinin A,Silybin,Silymarin I	Reactive Oxygen Species , Autophagy
	Silibinin (Silybin) is the major active constituent of silymarin, a standardized extract of the milk thistle seeds, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silicristin, silidianin an...		Reactive Oxygen Species , Autophagy
T21771	Pyoluteorin		Antibiotic
	Pyoluteorin is an antibiotic that inhibits Oomycete fungi, including the plant pathogen Pythium ultimum, and suppresses plant diseases caused by this fungus. Pyoluteorin induces human triple-negative breast cancer MDA-MB...		Antibiotic
T7032	Eupatorin		Others , P450
	Eupatorin has antiproliferative and antiangiogenic effects. Eupatorin has antiproliferative and cytostatic effects on MDA-MB-468 human breast cancer cells due to CYP1-mediated metabolism. Eupatorin-induced cell death is ...		Others , P450
T5S0053	Coptisine	Coptisin	Indoleamine 2,3-Dioxygenase (IDO)
	1. Coptisine (Coptisin) treatment increases cell viability based on its reversal effect on the enhanced activity of Indoleamine 2, 3-dioxygenase . 2. Coptisine treats myocardial I/R likely through suppressing myocardial ...		Indoleamine 2,3-Dioxygenase (IDO)
T5S2059	Glaucine		Calcium Channel , Dopamine Receptor , Influenza Virus , Adrenergic Receptor , PDE
	Glaucine has antitussive, antioxidative potential and antiviral activities, it may be an anti-arthritic agent, it can enhance LPS and zymosan-induced IL-10 production. Glaucine can inhibit the migration and invasion of h...
T3717	Hinokitiol	4-Isopropyltropolone,β-thujaplicin	DNA Methyltransferase , Virus Protease , Estrogen/progestogen Receptor , Nrf2
	Hinokitiol (4-Isopropyltropolone) can inhibit ultraviolet B-induced apoptosis in keratinocytes and strongly suggest that the inhibitory mechanism is due to the antioxidant activity of metallothionein induced by the agent...
T2966	Beta-Sitosterol	Cupreol,Beta-Sitosterol,β-Sitosterol,Azuprostat,SKF 14463,22,23-Dihydrostigmasterol,Betaprost	Apoptosis , Lipase , Endogenous Metabolite
	Beta-Sitosterol (SKF 14463) has recently been shown to induce G2/M arrest, endoreduplication, and apoptosis through the Bcl-2 and PI3K/Akt signaling pathways. Beta-Sitosterol (SKF 14463) , a main dietary phytosterol foun...		Apoptosis , Lipase , Endogenous Metabolite
T3923	Calycosin	Cyclosin,3'-Hydroxyformononetin	Apoptosis , Tyrosinase
	Calycosin (Cyclosin) acts as a selective estrogen receptor modulator. Calycosin induces apoptosis in human ovarian cancer SKOV3 cells by activating caspases and Bcl-2 family proteins. Calycosin suppresses breast cancer c...		Apoptosis , Tyrosinase
TN4171	Grossamide		NO Synthase
	Grossamide (GSE) Grossamide is a lignan amide derived from thioguanosine.6-Thioguanosine (GSE) is a selective and potent miR-210 (miRNA-210) inhibitor.6-Thioguanosine (GSE) is a selective and potent miR-210 (miRNA-210) i...		NO Synthase
TL0008	Gigantol		Wnt/beta-catenin , Glucosidase
	Gigantol is a novel inhibitor of the Wnt/β-catenin pathway. It inhibits Wnt/β-catenin signaling through downregulation of phosphorylated LRP6 and cytosolic β-catenin in breast cancer cells. Gigantol may be developed as a...		Wnt/beta-catenin , Glucosidase
T2S2043	Dracorhodin perchlorate	Dracorhodin perochlorate,Dracohodin perochlorate	Apoptosis , Others
	Dracorhodin perchlorate inhibits cell growth, and induces apoptosis in fibroblasts in a dose-and time-dependent manner, arresting cell cycle at G1 phase, may as a candidate for anti-breast cancer. Dracorhodin perchlorate...		Apoptosis , Others
TJS0387	Desoxyrhaponticin	Deoxyrhapontin,Deoxyrhaponticin	Apoptosis , Fatty Acid Synthase
	1. Desoxyrhaponticin (Deoxyrhaponticin) is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes, the in vivo antidiabetic action of this compound can be explained, in part at least...		Apoptosis , Fatty Acid Synthase
T7190	Actein		Apoptosis , Akt , JNK , Autophagy
	Actein has a stimulatory effect on osteoblastic bone formation or has potential activity against osteoporosis, it also can prevent oxidative damage to osteoblasts in osteoporotic patients. Actein's ability to pathways in...		Apoptosis , Akt , JNK , Autophagy
T4S0797	Berberine	Berberin,Umbellatine	Reactive Oxygen Species , Topoisomerase , Endogenous Metabolite , Antibacterial , Antibiotic , Autophagy
	1. Berberine (Umbellatine) is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism. 2. Berberine may as a broad-spectrum anti-microbial medicine, a complementary therapeutic agent for HIV/AIDS. 3....
T2973	Astragaloside IV	AST-IV,AS-IV	MMP , ERK , Estrogen/progestogen Receptor , JNK
	Astragaloside IV (AS-IV), an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cel...		MMP , ERK , Estrogen/progestogen Receptor , JNK
TN5371	8-Hydroxy-ar-turmerone
	8-Hydroxy-ar-turmerone may exhibit antitumor activity against breast cancer cells via cell death and cell cycle arrest.
T3S0205	β-Hederin	Beta-Hederin	Parasite
	1. β-Hederin has antileishmanial activity. 2. β-Hederin has apoptotic effect on breast cancer cells, it could be a promising candidate for chemotherapy of breast cancer.		Parasite
TN1062	Peonidin chloride		ERK , COX
	Peonidin chloride has antioxidant activity. Peonidin has show potent inhibitory and apoptotic effects on cancer cells in vitro, notably metastatic human breast cancer cells.		ERK , COX
TN4321	Isopteleine		Others
	Isopteleine shows weak cytotoxic activities against human breast cancer cells (MCF7).		Others
TN3650	Chrysothol		Antifection
	Chrysothol shows strong antimicrobial activities (MICs=50-100 ug/ml) against enterobacteria E. coli and S. enteritidis. It also shows anti-cancer activity against human breast cancer cells.		Antifection
T69368	GKK1032B
	GKK1032B is a fungal metabolite that has antiproliferative and antibacterial activities. GKK1032B inhibits the growth of HeLa S3 cervical and MCF-7 breast cancer cells and Vero cells. It also inhibits the growth of B. su...
TN4330	Isoshinanolone		Others
	Isoshinanolone shows excellent toxicity with LC(50) values of 1.26 microg/mL. trans-Isoshinanolone shows cytotoxicity against MDA-MB-231 breast cancer cells.		Others
TN2288	Uralenol		Others , Estrogen/progestogen Receptor , Tyrosinase
	Uralenol significantly shows the inhibitory activities against the PTP1B enzyme; it also shows inhibitory activities on mushroom tyrosinase using l-tyrosine as substrate( IC50 =49.5 μM). Uralenol shows potent anti-prolif...		Others , Estrogen/progestogen Receptor , Tyrosinase
T40562	24-Methylenecycloartanyl ferulate
	24-Methylenecycloartanyl ferulate, a compound belonging to the γ-oryzanol family, demonstrates the ability to enhance parvin-beta expression within human breast cancer cells. Furthermore, it exhibits potential as an ATP-...
TN2691	2',3'-Dehydrosalannol		BCL , Akt , Caspase
	2',3'-Dehydrosalannol possesses antifeedant activity against Spodptera litura. It shows anticancer effects on triple-negative breast cancer(TNBC), it inhibits cathepsin-mediated pro-survival signaling which resulted in g...		BCL , Akt , Caspase
T75484	Clionamine B
	Clionamine B, an aminosteroid derived from the sponge Cliona celata, significantly enhances autophagy in human breast cancer MCF-7 cells [1].
TN4038	Eupatolide		TNF , NOS , NF-κB , ROS , MAPK , Akt , COX , DNA/RNA Synthesis , Nrf2 , PDGFR , NO Synthase , Prostaglandin Receptor , Autophagy

TN6419	Chamaejasmine
	Chamaejasmine could be a candidate drug for osteosarcoma and breast cancer chemoprevention, induces apoptosis in MG63 and HEp-2 cells by Akt inactivation and dephosphorylation of BAD. It inhibits Bcl-2 expression and ind...
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天然物製品

Neogambogic acid

T5724

Synonym: neo-gambogic acid

Target: Apoptosis, Others, Antibacterial

3',4'-Dimethoxyflavone

TN2883

Synonym:

Target: Others, PARP

Estrone sulfate sodium

T36857

Synonym: Estrone 3-sulfate (sodium salt),17β-Estrone 3-sulfate

Target: Endogenous Metabolite

Genistin

T2882

Synonym: Genistoside,Genistein glucoside,Genistein 7-glucoside,Genistine,Genistein 7-O-β-D-glucopyranoside

Target: Apoptosis, Estrogen Receptor/ERR, Others

6,8-Diprenylnaringenin

TN3150

Synonym: Senegalensin,Lonchocarpol A

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

Ginsenoside F2

T3916

Synonym:

Target: Apoptosis, Endogenous Metabolite, Autophagy

Ethyl gallate

T3729

Synonym: Nipagallin A,Phyllemblin,gallic acid ethyl ester

Target: MMP, NF-κB, Akt, Antibacterial

9-hydroxy-4-androstene-3,17-dione

Target: Apoptosis, JNK, Autophagy

Tetramethylcurcumin

TN2269

Synonym:

Target: Apoptosis, STAT

Ziyuglycoside II

T6S2038

Synonym:

Target: Apoptosis, Antioxidant, Reactive Oxygen Species

Britannin

T5793

Synonym:

Target: Apoptosis, AMPK, Autophagy

4-Demethyldeoxypodophyllotoxin

T83321

Synonym:

Target: Chk

Demethylwedelolactone

T5S0689

Synonym:

Target: Serine Protease

Synonym: 27-Deoxyactein,23-epi-26-Deoxyactein

Target: NOS, CDK, NO Synthase

2-Hydroxychalcone

T7979

Synonym: 2-(2-Hydroxybenzal)Acetophenone

Target: Apoptosis, BCL, Others, NF-κB

Demethoxycurcumin

T6S1683

Synonym: Curcumin II,Desmethoxycurcumin,Monodemethoxycurcumin

Target: Apoptosis, Antioxidant, Antibacterial, Autophagy

Herbacetin

T5S1331

Synonym:

Target: c-Met/HGFR, Akt

Nitidine chloride

T5S0761

Synonym:

Target: Apoptosis, ERK, FAK, p38 MAPK, NF-κB, Topoisomerase, STAT, Parasite

Silibinin

T1660

Synonym: Silibinin A,Silybin,Silymarin I

Target: Reactive Oxygen Species, Autophagy

Target: Indoleamine 2,3-Dioxygenase (IDO)

Glaucine

T5S2059

Synonym:

Target: Calcium Channel, Dopamine Receptor, Influenza Virus, Adrenergic Receptor, PDE

Hinokitiol

T3717

Synonym: 4-Isopropyltropolone,β-thujaplicin

Target: DNA Methyltransferase, Virus Protease, Estrogen/progestogen Receptor, Nrf2

Beta-Sitosterol

T2966

Synonym: Cupreol,Beta-Sitosterol,β-Sitosterol,Azuprostat,SKF 14463,22,23-Dihydrostigmasterol,Betaprost

Target: Apoptosis, Lipase, Endogenous Metabolite

Calycosin

T3923

Synonym: Cyclosin,3'-Hydroxyformononetin

Target: Apoptosis, Tyrosinase

Target: Wnt/beta-catenin, Glucosidase

Dracorhodin perchlorate

T2S2043

Synonym: Dracorhodin perochlorate,Dracohodin perochlorate

Target: Apoptosis, Others

Desoxyrhaponticin

TJS0387

Synonym: Deoxyrhapontin,Deoxyrhaponticin

Target: Apoptosis, Fatty Acid Synthase

Actein

T7190

Synonym:

Target: Apoptosis, Akt, JNK, Autophagy

Berberine

T4S0797

Synonym: Berberin,Umbellatine

Target: Reactive Oxygen Species, Topoisomerase, Endogenous Metabolite, Antibacterial, Antibiotic, Autophagy

Astragaloside IV

T2973

Synonym: AST-IV,AS-IV

Target: MMP, ERK, Estrogen/progestogen Receptor, JNK

8-Hydroxy-ar-turmerone

Synonym: Beta-Hederin

Target: Others, Estrogen/progestogen Receptor, Tyrosinase

24-Methylenecycloartanyl ferulate

T40562

Synonym:

Target:

2',3'-Dehydrosalannol

TN2691

Synonym:

Target: BCL, Akt, Caspase

Target: TNF, NOS, NF-κB, ROS, MAPK, Akt, COX, DNA/RNA Synthesis, Nrf2, PDGFR, NO Synthase, Prostaglandin Receptor, Autophagy

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPK-00194	TFPI Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Oestrogens influence the pathophysiology and development of hormone-sensitive cancers, such as breast cancer. Tissue factor pathway inhibitor (TFPI) is a serine protease inhibitor of the extrinsic coagulation pathway and...
TMPK-00195	TFPI Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Oestrogens influence the pathophysiology and development of hormone-sensitive cancers, such as breast cancer. Tissue factor pathway inhibitor (TFPI) is a serine protease inhibitor of the extrinsic coagulation pathway and...
TMPY-05160	PFKP Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	PFKP plays a critical role in cell proliferation in breast cancer cells. PFKP is necessary for starvation-mediated autophagy, glycolysis, and EMT, thereby promoting the malignant progression of OSCC. The Snail-PFKP axis ...
TMPK-00941	TFF1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Breast cancer (BC) is the most common cancer in women and the second leading cause of their cancer death. Establishing an accurate BC prognosis is very difficult because of its heterogeneity. Elevated TFF1 levels in seru...
TMPY-03979	ARHI Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	ARHI, also known as DIRAS3, belongs to the small GTPase superfamily, Di-Ras family. ARHI gene is a novel tumor suppressor gene located on chromosome 1p31. Downregulation of ARHI expression has been detected in many types...
TMPK-01375	PRLR Protein, Canine, Recombinant (hFc)	Canine	HEK293 Cells
	Prolactin receptor (PRLR) is highly expressed in a subset of human breast cancer and prostate cancer, which makes it a potential target for cancer treatment. In clinical trials, the blockade of PRLR was shown to be safe ...
TMPK-00007	TFF1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Breast cancer (BC) is the most common cancer in women and the second leading cause of their cancer death. Establishing an accurate BC prognosis is very difficult because of its heterogeneity. Elevated TFF1 levels in seru...
TMPY-00585	Annexin A8 Protein, Human, Recombinant (His)	Human	E. coli
	We have previously shown that Annexin A8 (ANXA8) is strongly associated with the basal-like subgroup of breast cancers, including BRCA1-associated breast cancers, and poor prognosis; while in the mouse mammary gland AnxA...
TMPY-06226	SLC39A6/LIV-1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Along with the SLC30 family, SLC39 family members regulate zinc movement in cells. SLC39 metal ion transporters accumulate zinc into the cytosol. SLC39A6, also known as LIV-1, belongs to a new subfamily of Zrt, Irt-like ...
TMPY-04984	CXCL17 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Chemokine (C-X-C motif) ligand 17 (CXCL17) is the latest member of the chemokine family. CXCL17 is a potential oncogene and promising therapeutic target, is an independent biomarker of poor prognosis in patients with bre...
TMPY-02763	DEP-1 Protein, Human, Recombinant (aa 997-1337, His)	Human	E. coli
	DEP1 / PTPRJ (Receptor-type tyrosine-protein phosphatase eta) is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, includin...
TMPK-00547	PRLR Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Prolactin receptor (PRLR) is highly expressed in a subset of human breast cancer and prostate cancer, which makes it a potential target for cancer treatment. In clinical trials, the blockade of PRLR was shown to be safe ...
TMPJ-01155	PDCD4 Protein, Human, Recombinant (His)	Human	E. coli
	Programmed Cell Death Protein 4 (PDCD4) is a member of the PDCD4 family. PDCD4 and EIF4A1 form a heterotrimer. One molecule of PDCD4 binds two molecules of EIF4A1. PDCD4 takes part in apoptosis via inhibiting translation...
TMPK-00868	Notch 4 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	The Notch signaling pathway is important for cell-cell communication; it is involved in gene regulation mechanisms that control multiple cell differentiation processes during embryonic and adult life. Notch-4 expression ...
TMPY-04203	RAB1B Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	RAB1B, a member of the RAS oncogene family, was significantly down-regulated in highly metastatic breast cancer cells. Moreover, down-regulation of RAB1B was also found to promote the proliferation and migration of TNBC ...
TMPK-00979	EPhA2 Protein, Cynomolgus, Recombinant (His & Avi)	Cynomolgus	HEK293 Cells
	Ephrin type-A receptor 2 (EPHA2) is a receptor tyrosine kinase (RTK), whose over-expression has been observed in a variety of cancers, including breast cancer. EPHA2 expression may be causally related to tumorigenesis; t...
TMPK-00980	EPhA2 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293 Cells
	Ephrin type-A receptor 2 (EPHA2) is a receptor tyrosine kinase (RTK), whose over-expression has been observed in a variety of cancers, including breast cancer. EPHA2 expression may be causally related to tumorigenesis; t...
TMPY-01583	ALDH1A1 Protein, Human, Recombinant (His)	Human	E. coli
	Aldehyde dehydrogenase 1 family, member A1 (ALDH1A1), also known as Aldehyde dehydrogenase 1 (ALDH1), or Retinaldehyde Dehydrogenase 1 (RALDH1), is an enzyme that is expressed at high levels in stem cells and that has be...
TMPK-01309	LRRC15 Protein, Canine, Recombinant (His)	Canine	HEK293 Cells
	The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation. LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge ...
TMPK-01070	LRRC15 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation. LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge ...
TMPK-01380	LRRC15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)	Cynomolgus,Rhesus	HEK293 Cells
	The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation. LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge ...
TMPJ-00160	EMMPRIN/CD147 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) belongs to the immunoglobulin superfamily, which has the homology to both the immunoglobulin V domain and MHC class II antigen β-chain. EMMPRIN is a transmembrane ...
TMPY-06815	SYAP1 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Synapse-associated protein 1 (SYAP1), also known as PRO3113 and BSTA, belongs to the synapse-associated BSD domain family, featuring three α-helices and two conserved tryptophan and phenylalanine residues located at the ...
TMPY-02442	ELK1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	E twenty-six (ETS)-like transcription factor 1, also known as Elk1 or Member of ETS oncogene family (ELK1), is a member of the ETS oncogene superfamily which is characterized by a common protein domain that regulates DNA...
TMPK-00933	ADAM8/CD156a Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	A Disintegrin And Metalloproteinase (ADAM) proteases constitute a family of multifunctional, membrane-bound proteins with traditional sheddase functions. Their protumorigenic potential has been attributed to both, essent...
TMPK-01217	MFAP5 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Human basal-like breast cancer (BLBC) is an aggressive malignancy with poor prognosis. Since most current treatments are ineffective, there is an urgent need to identify therapeutic targets for BLBC. Microfibrillar-assoc...
TMPK-00338	LRRC15 Protein, Human, Recombinant (His & Avi)	Human	CHO Cells
	The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation. LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge ...
TMPY-02384	MTSS1 Protein, Human, Recombinant (aa1-250, His & MBP)	Human	E. coli
	MTSS1 (Metastasis suppressor 1), also known as Missing in metastasis (MIM), is a tissue-specific regulator of plasma membrane dynamics. MTSS1 is well described for its function as a metastasis suppressor gene and is expr...
TMPJ-00933	PRDX5 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Peroxisomes are essential organelles that participate in multiple important metabolic processes, including the β-oxidation of fatty acids, plasmalogen synthesis, and the metabolism of reactive oxygen species (ROS). Perox...
TMPK-00957	MFAP5 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Human basal-like breast cancer (BLBC) is an aggressive malignancy with poor prognosis. Since most current treatments are ineffective, there is an urgent need to identify therapeutic targets for BLBC. Microfibrillar-assoc...
TMPY-03287	RRM1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	RRM1 is a subunit of ribonucleoside-diphosphate reductase which is constituted by two subunits. Ribonucleoside-diphosphate reductase is an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesi...
TMPK-00918	ADAM8/CD156a Protein, Human, Recombinant (aa 17-655, His)	Human	HEK293 Cells
	A Disintegrin And Metalloproteinase (ADAM) proteases constitute a family of multifunctional, membrane-bound proteins with traditional sheddase functions. Their protumorigenic potential has been attributed to both, essent...
TMPJ-00546	EFNA1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1 can be induced by TNF and IL1B. Its expression levels can ...
TMPY-02122	IFNGR2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Interferon-gamma receptor beta chain (IFNgammaR2), also known as IFNGR2, belongs to the type II cytokine receptor family, whose deficiency is a cause of autosomal recessive mendelian susceptibility to mycobacterial disea...
TMPY-01033	IL-32 Protein, Human, Recombinant (isoform alpha, His)	Human	HEK293 Cells
	IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathw...
TMPJ-00852	CCL2 Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	Monocyte chemoattractant protein 1 (MCP-1), also called CCL2, is a member of the beta (C-C) subfamily of chemokines that is a chemoattractant for monocytes and basophils but not eosinophils or neutrophils. CCL2 binds the...
TMPJ-00924	Decorin Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Decorin, also known as PG40 and DCN, is a member of the class I family of small leucine-rich proteoglycans (SLRPs) that is expressed in the stroma of various forms of cancer and has been recently proposed to act as a gua...
TMPJ-01089	TFF1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Trefoil Factor 1 (TFF1) belongs to the three structurally related secreted proteins that contain trefoil domains.TFF1 is an approximately peptide that has an important effect in epithelial regeneration and wound healing...
TMPY-02760	CALML3 Protein, Human, Recombinant (His)	Human	E. coli
	Calmodulin-like protein 3 (CALML3) is similar to that of authentic calmodulin and may actually compete with calmodulin by binding, with different affinity, to cellular substrates. Calmodulin-like protein 3 (CALML3) is a ...
TMPY-02100	TEM7 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Plexin domain-containing protein 1, also known as tumor endothelial marker 3, tumor endothelial marker 7 and PLXDC1 and TEM3, is a secreted, cytoplasm and single-pass type I membrane protein that belongs to the plexin fa...
TMPJ-00993	CCL5 Protein, Rat, Recombinant (E. coli, His)	Rat	E. coli
	C-C motif chemokine 5(CCL5) is a β-chemokine that plays a primary role in the inflammatory immune response by means of its ability to attract and activate leukocytes. CCL5 is secreted by many cell types at inflammatory s...
TMPY-01383	PRMT6 Protein, Human, Recombinant (His & Flag)	Human	HEK293 Cells
	Protein arginine N-methyltransferase 6, also known as Histone-arginine N-methyltransferase PRMT6, PRMT6, and HRMT1L6, is a member of the protein arginine N-methyltransferase family and PRMT6 subfamily. PRMT6 is highly ex...
TMPY-01775	AIM2 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	AIM2, Absent In Melanoma 2 is a member of the interferon-inducible HIN-200 protein family that contains an amino-terminal pyrin domain and a carboxy-terminal oligonucleotide/oligosaccharide-binding domain, senses cytopla...
TMPY-04084	ANGPTL1 Protein, Canine, Recombinant (hFc)	Canine	HEK293 Cells
	Angiopoietin-like protein 1 (ANGPTL1) has been reported to suppress migration and invasion in lung and breast cancer, acting as a novel tumor suppressor candidate. Downregulation of tumor suppressor signaling plays an im...
TMPY-01249	Cathepsin V Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cathepsin V (CTSV), also known as Cathepsin L2, CTSL2, and CATL2, is a member of the peptidase C1 family. It is predominantly expressed in the thymus and testis. Cathepsin V is also expressed in corneal epithelium, and t...
TMPJ-00785	FABP3 Protein, Human, Recombinant (His)	Human	E. coli
	Fatty Acid Binding Protein 3 (FABP3) is a small cytoplasmic protein (15 kDa) that is released from cardiac myocytes following an ischemic episode. Like the nine other distinct FABPs that have been identified, FABP3 is in...
TMPY-01268	SMYD3 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	SET and MYND domain-containing protein 3, also known as Zinc finger MYND domain-containing protein 1, SMYD3, and ZMYND, is a member of the histone-lysine methyltransferase family. SMYD3 contains one MYND-type zinc finger...
TMPH-03753	MYLK Protein, Human, Recombinant (His)	Human	E. coli
	Calcium/calmodulin-dependent myosin light chain kinase implicated in smooth muscle contraction via phosphorylation of myosin light chains (MLC). Also regulates actin-myosin interaction through a non-kinase activity. Phos...

TFPI Protein, Human, Recombinant (His & Avi)

TMPK-00194

Species: Human

Expression System: HEK293 Cells

TFPI Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00195

Species: Human

Expression System: HEK293 Cells

PFKP Protein, Human, Recombinant (His & GST)

TMPY-05160

Species: Human

Expression System: Baculovirus Insect Cells

TFF1 Protein, Mouse, Recombinant (hFc)

TMPK-00941

Species: Mouse

Expression System: HEK293 Cells

ARHI Protein, Human, Recombinant (mFc)

TMPY-03979

Species: Human

Expression System: HEK293 Cells

PRLR Protein, Canine, Recombinant (hFc)

TMPK-01375

Species: Canine

Expression System: HEK293 Cells

TFF1 Protein, Human, Recombinant (hFc)

TMPK-00007

Species: Human

Expression System: HEK293 Cells

Annexin A8 Protein, Human, Recombinant (His)

TMPY-00585

Species: Human

Expression System: E. coli

SLC39A6/LIV-1 Protein, Cynomolgus, Recombinant (His)

TMPY-06226

Species: Cynomolgus

Expression System: HEK293 Cells

CXCL17 Protein, Human, Recombinant (His)

TMPY-04984

Species: Human

Expression System: P. pastoris (Yeast)

DEP-1 Protein, Human, Recombinant (aa 997-1337, His)

TMPY-02763

Species: Human

Expression System: E. coli

PRLR Protein, Cynomolgus, Recombinant (His)

TMPK-00547

Species: Cynomolgus

Expression System: HEK293 Cells

PDCD4 Protein, Human, Recombinant (His)

TMPJ-01155

Species: Human

Expression System: E. coli

Notch 4 Protein, Mouse, Recombinant (His)

TMPK-00868

Species: Mouse

Expression System: HEK293 Cells

RAB1B Protein, Human, Recombinant (hFc)

TMPY-04203

Species: Human

Expression System: HEK293 Cells

EPhA2 Protein, Cynomolgus, Recombinant (His & Avi)

TMPK-00979

Species: Cynomolgus

Expression System: HEK293 Cells

EPhA2 Protein, Cynomolgus, Recombinant (hFc)

TMPK-00980

Species: Cynomolgus

Expression System: HEK293 Cells

ALDH1A1 Protein, Human, Recombinant (His)

TMPY-01583

Species: Human

Expression System: E. coli

LRRC15 Protein, Canine, Recombinant (His)

TMPK-01309

Species: Canine

Expression System: HEK293 Cells

LRRC15 Protein, Mouse, Recombinant (His)

TMPK-01070

Species: Mouse

Expression System: HEK293 Cells

LRRC15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

TMPK-01380

Species: Cynomolgus,Rhesus

Expression System: HEK293 Cells

EMMPRIN/CD147 Protein, Human, Recombinant (His)

TMPJ-00160

Species: Human

Expression System: HEK293 Cells

SYAP1 Protein, Human, Recombinant (His)

TMPY-06815

Species: Human

Expression System: Baculovirus Insect Cells

ELK1 Protein, Human, Recombinant (His & GST)

TMPY-02442

Species: Human

Expression System: Baculovirus Insect Cells

ADAM8/CD156a Protein, Mouse, Recombinant (His)

TMPK-00933

Species: Mouse

Expression System: HEK293 Cells

MFAP5 Protein, Mouse, Recombinant (hFc)

TMPK-01217

Species: Mouse

Expression System: HEK293 Cells

LRRC15 Protein, Human, Recombinant (His & Avi)

TMPK-00338

Species: Human

Expression System: CHO Cells

MTSS1 Protein, Human, Recombinant (aa1-250, His & MBP)

TMPY-02384

Species: Human

Expression System: E. coli

PRDX5 Protein, Human, Recombinant (His)

TMPJ-00933

Species: Human

Expression System: HEK293 Cells

MFAP5 Protein, Human, Recombinant (hFc)

TMPK-00957

Species: Human

Expression System: HEK293 Cells

RRM1 Protein, Human, Recombinant (His & GST)

TMPY-03287

Species: Human

Expression System: Baculovirus Insect Cells

ADAM8/CD156a Protein, Human, Recombinant (aa 17-655, His)

TMPK-00918

Species: Human

Expression System: HEK293 Cells

EFNA1 Protein, Human, Recombinant (hFc)

TMPJ-00546

Species: Human

Expression System: HEK293 Cells

IFNGR2 Protein, Mouse, Recombinant (His)

TMPY-02122

Species: Mouse

Expression System: HEK293 Cells

IL-32 Protein, Human, Recombinant (isoform alpha, His)

TMPY-01033

Species: Human

Expression System: HEK293 Cells

CCL2 Protein, Rat, Recombinant (His)

TMPJ-00852

Species: Rat

Expression System: HEK293 Cells

Decorin Protein, Mouse, Recombinant (His)

TMPJ-00924

Species: Mouse

Expression System: HEK293 Cells

TFF1 Protein, Mouse, Recombinant (His)

TMPJ-01089

Species: Mouse

Expression System: HEK293 Cells

CALML3 Protein, Human, Recombinant (His)

TMPY-02760

Species: Human

Expression System: E. coli

TEM7 Protein, Human, Recombinant (His)

TMPY-02100

Species: Human

Expression System: HEK293 Cells

CCL5 Protein, Rat, Recombinant (E. coli, His)

TMPJ-00993

Species: Rat

Expression System: E. coli

PRMT6 Protein, Human, Recombinant (His & Flag)

TMPY-01383

Species: Human

Expression System: HEK293 Cells

AIM2 Protein, Human, Recombinant (GST)

TMPY-01775

Species: Human

Expression System: Baculovirus Insect Cells

ANGPTL1 Protein, Canine, Recombinant (hFc)

TMPY-04084

Species: Canine

Expression System: HEK293 Cells

Cathepsin V Protein, Human, Recombinant (His)

TMPY-01249

Species: Human

Expression System: HEK293 Cells

FABP3 Protein, Human, Recombinant (His)

TMPJ-00785

Species: Human

Expression System: E. coli

SMYD3 Protein, Human, Recombinant (GST)

TMPY-01268

Species: Human

Expression System: Baculovirus Insect Cells

MYLK Protein, Human, Recombinant (His)

TMPH-03753

Species: Human

Expression System: E. coli

カタログ番号	製品名
L2191	Anti-Breast Cancer Compound Library	1939 compounds
	A unique collection of 1939 compounds with anti-breast cancer therapeutic activity or targeting breast cancer’s major signaling pathways, can be used for anti-breast cancer drug discovery and mechanism study；
L9420	Exosome Compound Library	76 compounds
	76 exosome-related compounds that can be used for high-throughput and high-content screening.

ライブラリー

Anti-Breast Cancer Compound Library

L2191

Compounds: 1939

Exosome Compound Library

L9420

Compounds: 76