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天然化合物

269

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カタログ番号	製品名	別名	ターゲット
T83775	STING Agonist 12L	Stimulator of Interferon Genes Agonist 12L
	STING agonist 12L is a stimulator of interferon genes (STING) agonist that exhibits binding affinity for both wild-type STING and its variants R232, AQ, and Q with half-maximal inhibitory concentrations (IC50s) of 1.15 µ...
T83841	STING Agonist D61	D61,Stimulator of Interferon Genes Agonist D61
	STING agonist D61 is a compound that activates the stimulator of interferon genes (STING), leading to the induction of IFN3-inducible secreted alkaline phosphatase (SEAP) and IFN-β-inducible reporter genes in cellular as...
T9029	STING-IN-3	C-171	STING
	STING-IN-3 (C-171) is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1.		STING
T13015	STING agonist-4		STING
	STING agonist-4 is an agonist of stimulator of Interferon Genes (STING) receptor(IC50 of 20 nM).		STING
T13613	ChX710		STING
	ChX710 activates the type I interferon response to cytosolic DNA by priming specific Interferon-Stimulated Genes (ISGs), inducing the ISRE promoter sequence, and facilitating the phosphorylation of Interferon Regulatory ...		STING
T6828	ZL0420		Epigenetic Reader Domain
	ZL0420 is a potent and selective bromodomain-containing protein 4 ( BRD4 ) inhibitor with nanomolar binding affinities to bromodomains (BDs) of BRD4. ZL0420 has IC 50 values of 27 nM against BRD4 BD1 and 32 nM against B...		Epigenetic Reader Domain
T7329	C-178		STING
	C-178 is a covalent inhibitor of STING, binds to Cys91 on STING to block its palmitoylation and prevents recruitment and phosphorylation of TBK1 in HEK293T cells.		STING
T9554	SN-008		STING
	SN-008 is a less active analog SN-011 which is a STING antagonist. SN-008 can be used as a negative control.		STING
T9853	STING activator Compound 53		STING
	STING activator Compound 53 based on an oxindole core structure demonstrated robust on-target functional activation of STING (human EC50 185 nM) in immortalised and primary cells and a cytokine induction fingerprint cons...		STING
T6919	Omaveloxolone	RTA-408	Apoptosis , Others , Nrf2 , STING
	Omaveloxolone (RTA-408) (RTA-408) is a synthetic triterpenoid that activates the cytoprotective transcription factor Nrf2 and inhibits NF-κB signaling. Phase 2.		Apoptosis , Others , Nrf2 , STING
T5674	H-151		STING
	H-151 is a highly potent and selective STING antagonist. H-151 covalently binds to Cys91 of STING and inhibits palmitoylation of Cys91, thereby inhibiting STING activity. H-151 can be used in the study of autoinflammator...		STING
T8655	SR-717		STING
	SR-717 is a cGAMP analog, a non-nucleoside STING agonist that induces a "closed" activation conformation of STING. SR-717 has antitumor activity and promotes activation of immune cells and cross-presentation of antigens.		STING
T8798	MSA-2		STING
	MSA-2 is a potent and orally available non-nucleotide STING agonist.		STING
T5154	C-176	C176,STING inhibitor 1	STING
	C-176 (STING inhibitor 1) is a strong, covalent mouse STING inhibitor		STING
T5516	DiABZI STING agonist-1 trihydrochloride		STING
	diABZI STING agonist-1 (trihydrochloride) is stimulator of interferon genes (STING) receptor agonist.		STING
T8328	STING agonist-1	G10	Virus Protease , STING
	STING agonist-1 (G10) is a human-specific STING agonist,elicits antiviral activity against emerging Alphaviruses.		Virus Protease , STING
T9028	STING-IN-2	C-170	STING
	STING-IN-2 (C-170) is a potent and covalent inhibitor of STING. C-170 efficiently inhibits both mouse STING (mmSTING) and human STING (hsSTING). It can be used for autoinflammatory disease research.		STING
T7081	CCCP	Carbonyl Cyanide m-Chlorophenylhydrazone,Carbonyl cyanide 3-chlorophenylhydrazone	Apoptosis , IκB/IKK , COX , Mitochondrial Metabolism , STING , IFNAR , Antibacterial
	CCCP (Carbonyl Cyanide m-Chlorophenylhydrazone) is an oxidative phosphorylation (OXPHOS) inhibitor and mitochondrial proton carrier uncoupler. CCCP inhibits the activation of STING and its downstream signaling molecules ...
T10252L2	ADU-S100 ammonium salt	ML RR-S2 CDA ammonium salt,MIW815 ammonium salt	STING
			STING
T9137	SN-011	[1,1'-Biphenyl]-4-carboxamide, N-[3-[[(4-fluorophenyl)sulfonyl]amino]-4-hydroxyphenyl]-,GUN35901	STING
	SN-011 (GUN35901) is a STING inhibitor, which inhibited the activation of the STING signal pathway and to prevent or treat a STING- mediated disease. It is a demethyl analogue of DUN99845.		STING
T0947	Dexamethasone acetate	Dexamethasone 21-acetate,Dexamethason acetate,NSC 39471	Glucocorticoid Receptor , Mitophagy , IL Receptor , Annexin A , NOS , Antibacterial , Autophagy
	Dexamethasone acetate (NSC 39471) is the acetate salt form of Dexamethasone, a synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addition to binding to specific nuclear steroid receptors, dexa...
T6273	Vadimezan	DMXAA,5,6-Dimethylxanthenone-4-acetic Acid,NSC 640488,ASA-404	Influenza Virus , VDA , STING , IFNAR
	Vadimezan (DMXAA) is a vascular disrupting agent, a murine STING agonist, and an inducer of cytokines such as type I IFN. Vadimezan has antitumor activity and induces a rapid cessation of blood flow in tumors without aff...		Influenza Virus , VDA , STING , IFNAR
T16269	Nanaomycin A		DNA Methyltransferase , Dehydrogenase , Parasite
	Nanaomycin A is the first selective DNMT3B inhibitor (IC50: 500 nM). Nanaomycin A inhibits in vitro growth of the human malaria parasite Plasmodium falciparum (IC80: 33.1 nM). Nanaomycin A is quinone antibiotics, reactiv...		DNA Methyltransferase , Dehydrogenase , Parasite
T71722	Angiogenesis inhibitor BT2
	Angiogenesis inhibitor BT2 is a novel inhibitor of angiogenesis and vascular permeability, inhibiting ERK phosphorylation and the expression of FosB/ΔFosB, VCAM-1, and many genes involved in proliferation, migration, ang...
T83116	Angiogenesis inhibitor 4
	Angiogenesis Inhibitor 4 is a potent agent for inhibiting angiogenesis, with potential applications in cancer research [1].
T74627	Angiogenesis inhibitor 3
	Angiogenesis Inhibitor 3 (Compound 8) is a potent substance that effectively inhibits the growth of HUVEC and HCT-15 cells, demonstrating IC50 values of 1.00 and 0.71 μM, respectively. It not only induces apoptosis in th...
T74217	Angiogenesis agent 1		HIF/HIF Prolyl-Hydroxylase
	Angiogenesis Agent 1 (Compound C-31), a glycoside analogue derived from salidroside, acts as an activator of the HIF-1α pathway and shows potential in diabetic hind limb ischemia research [1].		HIF/HIF Prolyl-Hydroxylase
T19853	Dimethoxycurcumin	Veratrylcurcuminoid	Others
	Dimethoxycurcumin (Veratrylcurcuminoid) is an analog of curcumin with more metabolical stability. Dimethoxycurcumin induces epigenetic changes in leukemia cells and the expression of promoter methylated genes.		Others
T3685	SR9009	Stenabolic,REV-ERB Agonist II	Autophagy
	SR9009 (Stenabolic), a REV-ERB agonist, increases the constitutive repression of genes regulated by REV-ERBα/ERBβ (IC50: 670/800 nM). Through activation of REV-ERB, SR9009 can decrease circadian locomotor activity during...		Autophagy
T23351	Shz 1		Others
	induces phenotypic differentiation		Others
T6889	MI-136		Apoptosis , Epigenetic Reader Domain , Androgen Receptor
	MI-136 inhibits expression of androgen receptor (AR) target genes that DHT induced.		Apoptosis , Epigenetic Reader Domain , Androgen Receptor
T2707	Pifithrin-α hydrobromide	Pifithrin hydrobromide,Pifithrin-α (PFTα) HBr,Pifithrin-α,PFTα,PFTα hydrobromide	Ferroptosis , Aryl Hydrocarbon Receptor , p53
	Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.		Ferroptosis , Aryl Hydrocarbon Receptor , p53
T22884	JW 67		Wnt/beta-catenin
	JW 67 is an inhibitor of canonical Wnt pathway signaling. JW 67 rapidly reduced active β-catenin with a subsequent downregulation of Wnt target genes, including AXIN2, SP5, and NKD1.		Wnt/beta-catenin
T9980	AVJ16		IGF-1R
	AVJ16 as a member of the insulin growth factor 2 mRNA-binding protein family, binds to the mRNA of certain genes to regulate protein translation.		IGF-1R
T3106	C-DIM12		Apoptosis , Others
	C-DIM12 induced expression of Nurr1-regulated genes. C-DIM12 increased expression of transfected human Nurr1, induced Nurr1 protein expression in primary dopaminergic neurons and enhanced neuronal survival from exposure ...		Apoptosis , Others
T20525	Chloramphenicol palmitate		Antibacterial , Antibiotic
	Chloramphenicol palmitate is a broad-spectrum antibiotic with activity against gram-positive and gram-negative bacteria. Chloramphenicol palmitate can be used in studies about acting as a bacterial selection agent in tra...		Antibacterial , Antibiotic
T2003	ISX-9	Isoxazole 9,Isoxazole 9 (ISX-9)	Calcium Channel , Wnt/beta-catenin
	ISX-9 (Isoxazole 9) is necessary to activate neuron-specific genes as neurogenesis inducer.		Calcium Channel , Wnt/beta-catenin
T62356	Mardepodect hydrochloride	PF-2545920 HCl,Mardepodect HCl,MP-10 HCl,PF-02545920 HCl	Apoptosis , PDE
	Mardepodect hydrochloride (Mardepodect HCl) is an orally active, selective and potent inhibitor of PDE10A that crosses the blood-brain barrier (IC50: 0.37 nM).Mardepodect hydrochloride up-regulates the expression of prot...		Apoptosis , PDE
T60008	BCL6-IN-6		BCL
	BCL6-IN-6 is an inhibitor of Bcl-6 and can be used in studies about diffuse large B-cell lymphoma. BCL6-IN-6 blocks the interaction of Bcl-6 with its corepressors and dose-dependently reactivates Bcl-6 target genes.		BCL
T4005	FDI-6	FDI6,FDI 6	Others
	FDI-6 is an effective and selective inhibitor of FOXM1 that blocks DNA binding. FDI-6(FDI6) binds to the FOXM1 protein and specifically downregulates FOXM1-activated genes.		Others
T11035	DiABZI STING agonist-1 (Tautomerism)	diABZI STING agonist (Compound 3)	STING
	diABZI STING agonist-1 (Tautomerism) (diABZI STING agonist (Compound 3)) is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively.		STING
T8710	MSAB		Wnt/beta-catenin
	MSAB is a selective inhibitor of Wnt/β-catenin signaling. MSAB binds to β-catenin, promoting its degradation, and specifically downregulates Wnt/β-catenin target genes.		Wnt/beta-catenin
T38766L	Histone H3 (1-35) acetate		Others
	Histone H3 (1-35) acetate is a 35-residue peptide of histone H3. Histone H3 is an important protein that plays a role in the dynamic and long term regulation of genes.		Others
T8979	AEM1		Nrf2
	AEM1 is an inhibitor of deregulated NRF2 transcriptional activity in cancer. AEM1 acts by broadly decreasing the expression of NRF2 controlled genes, sensitizing A549 cells to various chemotherapeutic agents, and inhibit...		Nrf2
T73322	TBK1-IN-1		IκB/IKK
	TBK1-IN-1 is a specific and potent TANK-binding kinase 1 (TBK1) inhibitor (IC50: 22.4 nM) with anticancer activity.TBK1-IN-1 inhibits the expression of TBK1 downstream target genes, cxcl10 and ifnβ.		IκB/IKK
T72482	Dazostinag disodium		STING
	Dazostinag disodium (TAK-676) is a novel stimulator of interferon genes (STING) agonist and immune system modulator with antitumor activity that activates dendritic cells, natural killer cells, and T cells.		STING
T9849	HQ461		CDK , Molecular Glues
	HQ461 is a molecular glue that promotes CDK12-DDB1 interaction to trigger cyclin K degradation, resulting in decreased CDK12 substrate phosphorylation, downregulation of DNA damage response genes, and cell death.		CDK , Molecular Glues
T39584	MI-3454
	MI-3454 is a highly potent, orally active, and selective inhibitor of the interaction between menin and MLL1, with an IC50 of 0.51 nM. This compound effectively inhibits the proliferation of leukemic cells and promotes t...
T16007	MALAT1-IN-1		Others
	MALAT1-IN-1 modulated Malat1 downstream genes in a dose-dependent manner without affecting the expression of nuclear enriched abundant transcript 1 (Neat1). MALAT1-IN-1 is an effective and specific Malat1 inhibitor.		Others
T3633	Crenigacestat	LY3039478	Gamma-secretase
	Crenigacestat (LY3039478) is an orally bioavailable Notch inhibitor with an IC50 of ~1 nM in most of the tumor cell lines tested. Crenigacestat effectively inhibits mutant Notch receptor activity. In a xenograft tumor mo...		Gamma-secretase

Compounds

STING Agonist 12L

T83775

Synonym: Stimulator of Interferon Genes Agonist 12L

Target:

STING Agonist D61

T83841

Synonym: D61,Stimulator of Interferon Genes Agonist D61

Target: Epigenetic Reader Domain

STING activator Compound 53

Target: Apoptosis, Others, Nrf2, STING

Synonym: C176,STING inhibitor 1

Target: STING

diABZI STING agonist-1 trihydrochloride

Target: Virus Protease, STING

Synonym: Carbonyl Cyanide m-Chlorophenylhydrazone,Carbonyl cyanide 3-chlorophenylhydrazone

Target: Apoptosis, IκB/IKK, COX, Mitochondrial Metabolism, STING, IFNAR, Antibacterial

ADU-S100 ammonium salt

T10252L2

Synonym: ML RR-S2 CDA ammonium salt,MIW815 ammonium salt

Target: STING

SN-011

T9137

Synonym: [1,1'-Biphenyl]-4-carboxamide, N-[3-[[(4-fluorophenyl)sulfonyl]amino]-4-hydroxyphenyl]-,GUN35901

Target: STING

Dexamethasone acetate

T0947

Synonym: Dexamethasone 21-acetate,Dexamethason acetate,NSC 39471

Target: Glucocorticoid Receptor, Mitophagy, IL Receptor, Annexin A, NOS, Antibacterial, Autophagy

Vadimezan

T6273

Synonym: DMXAA,5,6-Dimethylxanthenone-4-acetic Acid,NSC 640488,ASA-404

Target: Influenza Virus, VDA, STING, IFNAR

Nanaomycin A

T16269

Synonym:

Target: DNA Methyltransferase, Dehydrogenase, Parasite

Angiogenesis inhibitor BT2

T71722

Synonym:

Target:

Angiogenesis inhibitor 4

T83116

Synonym:

Target:

Angiogenesis inhibitor 3

Target: HIF/HIF Prolyl-Hydroxylase

Dimethoxycurcumin

T19853

Synonym: Veratrylcurcuminoid

Target: Others

SR9009

T3685

Synonym: Stenabolic,REV-ERB Agonist II

Target: Apoptosis, Epigenetic Reader Domain, Androgen Receptor

Pifithrin-α hydrobromide

T2707

Synonym: Pifithrin hydrobromide,Pifithrin-α (PFTα) HBr,Pifithrin-α,PFTα,PFTα hydrobromide

Target: Ferroptosis, Aryl Hydrocarbon Receptor, p53

JW 67

T22884

Synonym:

Target: Wnt/beta-catenin

Target: Apoptosis, Others

Chloramphenicol palmitate

T20525

Synonym:

Target: Antibacterial, Antibiotic

ISX-9

T2003

Synonym: Isoxazole 9,Isoxazole 9 (ISX-9)

Target: Calcium Channel, Wnt/beta-catenin

Mardepodect hydrochloride

T62356

Synonym: PF-2545920 HCl,Mardepodect HCl,MP-10 HCl,PF-02545920 HCl

Target: Apoptosis, PDE

diABZI STING agonist-1 (Tautomerism)

T11035

Synonym: diABZI STING agonist (Compound 3)

Target: Wnt/beta-catenin

Histone H3 (1-35) acetate

Target: CDK, Molecular Glues

Target: Gamma-secretase

カタログ番号	製品名	別名	ターゲット
T5S1252	Prosapogenin A	Progenin III	Apoptosis , Others
	Prosapogenin A (Progenin III) has anticancer activity.		Apoptosis , Others
TN2331	Eleutheroside B1		Influenza Virus
	Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits l...		Influenza Virus
T6S2123	Ginkgolic Acid	Romanicardic acid,Ginkgolic acid I,Ginkgolic acid (15:1),Ginkgolic acid C15:1	Others , E1/E2/E3 Enzyme
	Ginkgolic Acid (Romanicardic acid) C15:1 represses curli genes and prophage genes in EHEC.		Others , E1/E2/E3 Enzyme
T4S1796	Heterophyllin B		PI3K
	Heterophyllin B effectively suppresses the adhesion and invasion of the human esophageal carcinoma cells by mediating the PI3K/AKT/β-catenin pathways and regulating the expression levels of adhesion- and invasion-associa...		PI3K
T3976	Cytosporone B	Csn-B,Dothiorelone G	Others
	Cytosporone B (Dothiorelone G) is a naturally occurring agonist for the nuclear receptor Nur77 (IC50 = 0.278 nM). Activation of Nur77 with cytosporone B induces the expression of Nur77-dependent genes, including the gene...		Others
TN1273	7,4'-Dihydroxyflavone	4',7-Dihydroxyflavone	NF-κB , COX , HDAC , CCR , NOD
	7,4'-Dihydroxyflavone (4',7-Dihydroxyflavone) can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-2.		NF-κB , COX , HDAC , CCR , NOD
T1168	Desonide	Tridesilon,Locapred,Prednacinolone	Glucocorticoid Receptor
	Desonide (Prednacinolone) is a synthetic glucocorticosteroid for topical use, with anti-inflammatory activity. Desonide binds to glucocorticoid receptors in the cytoplasm, and the ligand-receptor complex is translocated ...		Glucocorticoid Receptor
T6808	Coelenterazine	Oplophorus luciferin,Coelenteramine	Others
	Coelenterazine (Coelenteramine) is a luminescent enzyme substrate, used for monitoring reporter genes in BRET, ELISA and HTS techniques.		Others
T0950	Neomycin sulfate	Framycin sulfate	Phospholipase , ribosome , Antibacterial , Antibiotic
	Neomycin sulfate (Framycin sulfate) is a broad-spectrum aminoglycoside antibiotic that blocks the synthesis of bacterial proteins in order to exert antimicrobial activity. Neomycin sulfate is commonly used to screen prok...		Phospholipase , ribosome , Antibacterial , Antibiotic
T3363	Jervine	Iervin,11-Ketocyclopamine,Jerwiny	Hedgehog/Smoothened , Smo
	The biological activity of Jervine (Jerwiny) is mediated via its interaction with the 7 passes transmembrane protein Smoothened. Jervine binds with and inhibits smoothened, which is an integral part of the Hedgehog signa...		Hedgehog/Smoothened , Smo
T1022	Hygromycin B	Hygrovetine	ribosome , Antibacterial , Antibiotic , Antifungal
	Hygromycin B (Hygrovetine) is an aminoglycoside antibiotic that inhibits protein synthesis by interfering with translocation and causing mistranslation of the 70S ribosome. Hygromycin B can be used to screen prokaryotic ...		ribosome , Antibacterial , Antibiotic , Antifungal
TN4234	Hydrangenol		NOS , NF-κB , Nrf2 , NO Synthase , Antifection , Autophagy
			NOS , NF-κB , Nrf2 , NO Synthase , Antifection , Autophagy
TQ0216	Ercalcitriol	1α,25-Dihydroxy Vitamin D2	Others
	Ercalcitriol (1α,25-Dihydroxy Vitamin D2) is an active metabolite of vitamin D2. Ercalcitriol, as the physiological activated form of vitamin D, can strengthen immunity via regulation of cathelicidin antimicrobial peptid...		Others
T6S2246	Alisol B 23-acetate	Alisol B Acetate,Alisol B monoacetate,23-O-Acetylalisol B,23-Acetylalismol B	Others
	1. Alisol B 23-acetate (Alisol B Acetate) produces protective effect against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regulation of transporters and enzymes. 2. Alisol B 23-acetate produces promotiv...		Others
TWS1977	Kamebakaurin	Kamebakaurine	NF-κB
	1. Kamebakaurin (Kamebakaurine) has the ability to protect the liver from APAP-induced hepatotoxicity, presumably by both inhibiting the inflammatory response and oxidative stress. 2. Kamebakaurin inhibits the expression...		NF-κB
T0034	Cortisone acetate	Cortisone 21-acetate,NSC 49420	Glucocorticoid Receptor , Endogenous Metabolite
	Cortisone Acetate is a synthetic or semisynthetic analog of the naturally occurring cortisone hormone produced by the adrenal glands with anti-inflammatory and immunomodulating properties. Cortisone acetate (NSC-49420) d...		Glucocorticoid Receptor , Endogenous Metabolite
T6S0119	Dauricine		Apoptosis , Others , NF-κB
	1. Dauricine has pulmonary toxicity, can produce pulmonary injury in CD-1 mice by the metabolism of Dauricine mediated by CYP3A. 2. Dauricinec can pass the blood-brain barrier, and that P-glycoprotein has an important ro...		Apoptosis , Others , NF-κB
T3864	Erianin		BCL , Antibacterial
	Erianin is a nature product extracted from Dendrobium chrysotoxum, has notable antitumour activity , can cause extensive tumour necrosis, growth delay. Erianin has antiangiogenic action by inhibiting endothelial metaboli...		BCL , Antibacterial
T5S1805	5,7-Dihydroxychromone	5,7-Dihydroxy-4H-Chromen-4-One	Others , Virus Protease , PARP , Caspase , Nrf2
	1. 5,7-Dihydroxychromone (5,7-Dihydroxy-4H-Chromen-4-One) isolated from DME is one of the active compounds that may contribute to regulate blood glucose levels. 2. 5,7-Dihydroxychromone exerts neuroprotective effect agai...		Others , Virus Protease , PARP , Caspase , Nrf2
T2915	Bardoxolone	RTA 401,CDDO	Others , Nrf2
	Bardoxolone (CDDO) is a synthetic oleanane triterpenoid that blocks the cellular synthesis of inducible nitric oxide synthase and inducible COX-2 in INF-γ-activated mouse macrophages with an IC50 value of 0.4 nM. By supp...		Others , Nrf2
TN1163	2'-Hydroxychalcone		Others
	2'-Hydroxychalcone is a drug synthesis intermediate for the synthesis of flavonoids. 2'-Hydroxychalcone loaded in nanoemulsion showed fungicidal activity against Coccidioides parapsilosis in Danio rerio model.2'-Hydroxyc...		Others
T0798	Triamcinolone	Fluoxyprednisolone,Aristocort,Rodinolone	Glucocorticoid Receptor , COX
	Triamcinolone (Aristocort) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. Upon cell entry, triamcinolone binds to and activates the glucocorticoid receptor, which leads to transloca...		Glucocorticoid Receptor , COX
T6491	(-)-(S)-Equol	(−)-Equol,Equol,4',7-Dihydroxyisoflavan,4',7-Isoflavandiol	Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Endogenous Metabolite
	(-)-(S)-Equol (4',7-Dihydroxyisoflavan) is an orally bioavailable, non-steroidal estrogen naturally produced by the metabolism of the isoflavonoid daidzein by human intestinal microflora, with potential chemoprotective a...
T4S2126	Ginkgetin		Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy
	1. Ginkgetin has anti-influenza virus and anti-fungal activities. 2. Ginkgetin has anti-inflammatory activity, can down-regulates COX-2 induction in vivo against skin inflammatory responses. 3. Ginkgetin is a good STAT3 ...		Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy
T4S1551	Cinnamaldehyde	Cinnamic Aldehyde	HIF
	1. Cinnamaldehyde (Cinnamic Aldehyde) has antipyretic activity. 2. Cinnamaldehyde is a sedative agent. 3. Cinnamaldehyde inhibits invasive capabilities of MDA-MB-435S cells was correlated with down-regulating the express...		HIF
TN4016	Ethyl 2,4,6-trihydroxybenzoate		Liver X Receptor
	Ethyl 2,4,6-trihydroxybenzoate is a dual-LXR modulator that regulates the expression of key genes in cholesterol homeostasis in multiple cells without inducing lipid accumulation in HepG2 cells. It suppresses cellular ch...		Liver X Receptor
TN4790	Pinobanksin 5-methyl ether		Others
	Pinobanksin 5-methyl ether can induce detoxification genes.		Others
T23825	Bryononic acid
	Bryononic acid is a new cucurbitane-type triterpenoid. Bryonolic acid transcriptional control of anti-inflammatory and antioxidant genes in macrophages in vitro and in vivo.
T40667	L-Azatyrosine
	L-Azatyrosine, an antitumor antibiotic derived from Streptomyces chibaensis, exhibits the ability to restore the normal phenotypic behavior of transformed cells that carry oncogenic Ras genes.
T40529	(R)-(-)-1,2-Propanediol
	(R)-(-)-1,2-Propanediol is the (R)-enantiomer of 1,2-Propanediol, which is derived from glucose through the expression of NADH-linked glycerol dehydrogenase genes in Escherichia coli.
TN4938	Samidin		p38 MAPK , TNF , NF-κB , COX , DNA/RNA Synthesis , JNK
	Samidin has anti-inflammatory properties through suppression of NF-ÎºB and AP-1-mediated-genes in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells.		p38 MAPK , TNF , NF-κB , COX , DNA/RNA Synthesis , JNK
T71896	Brevicompanine B
	Brevicompanine B is a fungal metabolite that has plant growth and circadian rhythm regulatory activity. Brevicompanine B inhibits primary root growth in Arabidopsis seedlings and disrupts the transcription of various gen...
TN2228	Soyasaponin Aa		PPAR
	Soyasaponin Aa and soyasaponin Ab dose-dependently markedly inhibit adipocyte differentiation and expression of various adipogenic marker genes, through the downregulation of the adipogenesis-related transcription factor...		PPAR
TN4383	Kazinol U		IL Receptor , IκB/IKK , NOS , NF-κB
	Kazinol U may have therapeutic value in delaying pancreatic β-cell destruction in type 1 diabetes by blocking the NF-ÎºB pathway in pancreatic β-cells reduces cell damage. Kazinol U shows estrogenic activity with ligand-...		IL Receptor , IκB/IKK , NOS , NF-κB
T38331	Commendamide
	Commendamide is a natural bacterial product that was discovered in a screen for commensal bacteria effector genes (Cbegs). Cbeg12 is a bacterial effector gene that encodes for its production. Commendamide is structurally...
T75672	Angoline hydrochloride
	Angoline hydrochloride, a selective inhibitor of the IL6/STAT3 signaling pathway, demonstrates potent activity with an IC50 value of 11.56 μM. It effectively inhibits STAT3 phosphorylation and the expression of its targe...
TN3539	Broussonin A		ERK , IL Receptor , IκB/IKK , NOS , NF-κB , Akt
	Broussonins A and B, new phytoalexins from diseased paper mulberry. Broussonin A shows estrogenic activity with ligand-binding activity of estrogen receptor, transcriptional activity of estrogen-responsive element-lucife...		ERK , IL Receptor , IκB/IKK , NOS , NF-κB , Akt
T73717	CGAMP diammonium
	cGAMP (Cyclic GMP-AMPP) diammonium serves as an intrinsic second messenger in metazoans, initiating the production of interferons upon cytosolic DNA detection. It activates the stimulator of interferon genes (STING), sub...
TN5369	Dehydroleucodine	Dehydroleucodin
	Dehydroleucodine has antidiarrheal, anti-inflammatory, anti-microbial, embryotoxicity, gastric cytoprotective, anti-cancer activities. Dehydroleucodine has an important inhibitory effect in cellular pathways regulating a...
TN1862	Licoflavonol		Antifection
	Licoflavonol is a novel natural inhibitor of Salmonella T3SS, could be a promising candidate for novel type of anti-virulence drugs, it exhibits a strong inhibitory effect on the secretion of the SPI-1 effector proteins ...		Antifection
TN3882	Dodoviscin A		cAMP , Tyrosinase , transporter
	Dodoviscin A may be a new promising pigmentation-altering agent for cosmetic and therapeutic applications, it can inhibit melanin biosynthesis induced by 3-isobutyl-1-methylxanthine and PD98059.Dodoviscin A can promote a...		cAMP , Tyrosinase , transporter
TN2775	2-Methoxystypandrone		MMP , BCL , IκB/IKK , GSK-3 , TNF , NOS , NF-κB , Wnt/beta-catenin , COX , JAK , STAT
	2-Methoxystypandrone displays an immunomodulatory effect in a cellular model, it blocks inflammatory responses by impairing NF-ÎºB signaling to limit the inflammation and oxidative stress for preservation of BBB integrit...
T37911	Cis-Resveratrol	(Z)-Resveratrol
	Resveratrol is a potent phenolic antioxidant found in grapes, red wine, and various berries that also has antiproliferative and anti-inflammatory activity. cis-Resveratrol is the double bond isomer of trans-resveratrol, ...
T36563	(E)-Guggulsterone
	Bile acids are essential for solubilization and transport of dietary lipids, are the major products of cholesterol catabolism, and are physiological ligands for farnesoid X receptor (FXR), a nuclear receptor that regulat...

天然物製品

Prosapogenin A

T5S1252

Synonym: Progenin III

Target: Apoptosis, Others

Eleutheroside B1

TN2331

Synonym:

Target: Influenza Virus

Ginkgolic Acid

T6S2123

Synonym: Romanicardic acid,Ginkgolic acid I,Ginkgolic acid (15:1),Ginkgolic acid C15:1

Target: Others, E1/E2/E3 Enzyme

Synonym: Csn-B,Dothiorelone G

Target: Others

7,4'-Dihydroxyflavone

TN1273

Synonym: 4',7-Dihydroxyflavone

Target: NF-κB, COX, HDAC, CCR, NOD

Desonide

T1168

Synonym: Tridesilon,Locapred,Prednacinolone

Target: Glucocorticoid Receptor

Coelenterazine

T6808

Synonym: Oplophorus luciferin,Coelenteramine

Target: Others

Neomycin sulfate

T0950

Synonym: Framycin sulfate

Target: Phospholipase, ribosome, Antibacterial, Antibiotic

Jervine

T3363

Synonym: Iervin,11-Ketocyclopamine,Jerwiny

Target: Hedgehog/Smoothened, Smo

Hygromycin B

T1022

Synonym: Hygrovetine

Target: ribosome, Antibacterial, Antibiotic, Antifungal

Hydrangenol

TN4234

Synonym:

Target: NOS, NF-κB, Nrf2, NO Synthase, Antifection, Autophagy

Ercalcitriol

TQ0216

Synonym: 1α,25-Dihydroxy Vitamin D2

Target: Others

Alisol B 23-acetate

T6S2246

Synonym: Alisol B Acetate,Alisol B monoacetate,23-O-Acetylalisol B,23-Acetylalismol B

Target: Others

Kamebakaurin

TWS1977

Synonym: Kamebakaurine

Target: NF-κB

Cortisone acetate

T0034

Synonym: Cortisone 21-acetate,NSC 49420

Target: Glucocorticoid Receptor, Endogenous Metabolite

Dauricine

T6S0119

Synonym:

Target: Apoptosis, Others, NF-κB

Erianin

T3864

Synonym:

Target: BCL, Antibacterial

5,7-Dihydroxychromone

T5S1805

Synonym: 5,7-Dihydroxy-4H-Chromen-4-One

Target: Others, Virus Protease, PARP, Caspase, Nrf2

Bardoxolone

T2915

Synonym: RTA 401,CDDO

Synonym: Fluoxyprednisolone,Aristocort,Rodinolone

Target: Glucocorticoid Receptor, COX

(-)-(S)-Equol

T6491

Synonym: (−)-Equol,Equol,4',7-Dihydroxyisoflavan,4',7-Isoflavandiol

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Endogenous Metabolite

Ginkgetin

T4S2126

Synonym:

Target: Apoptosis, Wnt/beta-catenin, COX, STAT, Autophagy

Cinnamaldehyde

T4S1551

Synonym: Cinnamic Aldehyde

Target: HIF

Ethyl 2,4,6-trihydroxybenzoate

TN4016

Synonym:

Target: Liver X Receptor

Pinobanksin 5-methyl ether

(R)-(-)-1,2-Propanediol

Target: p38 MAPK, TNF, NF-κB, COX, DNA/RNA Synthesis, JNK

Target: IL Receptor, IκB/IKK, NOS, NF-κB

Angoline hydrochloride

Target: ERK, IL Receptor, IκB/IKK, NOS, NF-κB, Akt

Synonym: Dehydroleucodin

Target: cAMP, Tyrosinase, transporter

2-Methoxystypandrone

TN2775

Synonym:

Target: MMP, BCL, IκB/IKK, GSK-3, TNF, NOS, NF-κB, Wnt/beta-catenin, COX, JAK, STAT

cis-Resveratrol

T37911

Synonym: (Z)-Resveratrol

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-05426	CREG1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CREG1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.5 kDa and the accession number is O75629.
TMPY-03559	CREG1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	CREG1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.5 kDa and the accession number is O88668.
TMPY-03420	CREG1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	CREG1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.9 kDa and the accession number is O88668.
TMPJ-01206	Sting Protein, Human, Recombinant (Sumo & His)	Human	E. coli
	Stimulator of Interferon Gene(Sting,TMEM173) belongs to the TMEM173 family. STING is 379 amino acids (aa) in length. It contains an N-terminal cytoplasmic region (aa 1-20), four transmembrane segments (aa 21-173), and a ...
TMPY-05346	CRISPR-Cas9 Protein, Streptococcus pyogenes, Recombinant (His)	Streptococcus pyogenes	Baculovirus Insect Cells
	CRISPR-Cas9 Protein, Streptococcus pyogenes, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 163 kDa and the accession number is Q99ZW2.
TMPY-03465	Flagellin Protein, Listeria monocytogenes, Recombinant (His)	Listeria monocytogenes	E. coli
	The role of flagella and motility in the attachment of the foodborne pathogen Listeria monocytogenes to various surfaces is mixed with some systems requiring flagella for an interaction and others needing only motility...
TMPH-03608	Phosphinothricin N-acetyltransferase Protein, S. viridochromogenes, Recombinant (His)	Streptomyces viridochromogenes	P. pastoris (Yeast)
	Inactivates phosphinothricin (PPT) by transfer of an acetyl group from acetyl CoA. This enzyme is an effector of phosphinothricin tripeptide (PTT or bialaphos) resistance. Phosphinothricin N-acetyltransferase Protein, S....
TMPH-03599	Streptopain Protein, S. pyogenes, Recombinant (His & SUMO)	Streptococcus pyogenes	E. coli
	Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelia...
TMPH-03609	Phosphinothricin N-acetyltransferase Protein, S. viridochromogenes, Recombinant (His & SUMO)	Streptomyces viridochromogenes	E. coli
	Inactivates phosphinothricin (PPT) by transfer of an acetyl group from acetyl CoA. This enzyme is an effector of phosphinothricin tripeptide (PTT or bialaphos) resistance. Phosphinothricin N-acetyltransferase Protein, S....
TMPY-06179	IdeS Protein, Streptococcus pyogenes, Recombinant (His & GST)	Streptococcus pyogenes	E. coli
	IdeS (IgG-degrading enzyme of Streptococcus pyogenes) is a secreted cysteine endopeptidase from the human pathogen S. pyogenes with an extraordinarily high degree of substrate specificity, catalyzing a single proteolytic...
TMPH-03598	Streptopain Protein, S. pyogenes serotype M28, Recombinant (His & SUMO)	Streptococcus pyogenes	E. coli
	Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelia...
TMPH-03594	Exotoxin type A Protein, S. pyogenes, Recombinant (His & SUMO)	Streptococcus pyogenes	E. coli
	Causative agent of the symptoms associated with scarlet fever, have been associated with streptococcal toxic shock-like disease and may play a role in the early events of rheumatic fever. Exotoxin type A Protein, S. pyog...
TMPH-03597	Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (E. coli, His & Myc)	Streptococcus pyogenes	E. coli
	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system...
TMPY-06023	IdeS Protein, Streptococcus pyogenes, Recombinant (His)	Streptococcus pyogenes	E. coli
	IdeS (IgG-degrading enzyme of Streptococcus pyogenes) is a secreted cysteine endopeptidase from the human pathogen S. pyogenes with an extraordinarily high degree of substrate specificity, catalyzing a single proteolytic...
TMPH-03595	APT Protein, S. pyogenes serotype M1, Recombinant (His & Myc)	Streptococcus pyogenes	P. pastoris (Yeast)
	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. APT Protein, S. pyogenes serotype M1, Recombinant (His & Myc) is expressed in yeast with N-10xHis an...
TMPH-03596	Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (His & Myc)	Streptococcus pyogenes	Baculovirus Insect Cells
	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10...
TMPH-02415	Lysyl endopeptidase Protein, Lysobacter enzymogenes, Recombinant (His & SUMOstar)	Lysobacter enzymogenes	P. pastoris (Yeast)
	Highly specific endopeptidase that hydrolyzes lysyl bonds including the Lys-Pro bond. Lysyl endopeptidase Protein, Lysobacter enzymogenes, Recombinant (His & SUMOstar) is expressed in yeast with N-6xHis-SUMOSTAR tag. The...
TMPY-04310	Apolipoprotein A-IV/APOA4 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Apolipoprotein is genetically associated with the risk of Alzheimer's disease (AD). The APOA1, APOC3, and APOA4 genes are closely linked and located on human chromosome 11. There was a decreased trend for levels of APOA1...
TMPJ-00603	TL1A/TNFSF15 Protein, Mouse, Recombinant	Mouse	E. coli
	Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-specific gene, and recombinant TNFSF15 is a potent inhibitor ...
TMPY-05004	FGF-4 Protein, Human, Recombinant	Human	E. coli
	FGF (fibroblast growth factor) signalling is known to be required for many aspects of mesoderm formation and patterning during Xenopus development and has been implicated in regulating genes required for the specificati...
TMPJ-01466	Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His)	Human	HEK293 Cells
	TNFRSF11B is a secreted protein, containing 2 death domains and 4 TNFR-Cys repeats. TNFRSF11B is a decoy receptor for the receptor activator of nuclear factor kappa B ligand (RANKL). By binding RANKL, TNFRSF11B inhibits ...
TMPY-01964	CD16a Protein, Human, Recombinant (F176V, His)	Human	HEK293 Cells
	The Fc receptor with low affinity for IgG (FCGR3, or CD16) is encoded by 2 nearly identical genes, FCGR3A and FCGR3B, resulting in tissue-specific expression of alternative membrane-anchored isoforms. FCGR3A, it is also ...
TMPY-02062	SULT1A1 Protein, Human, Recombinant (His)	Human	E. coli
	Sulfate conjugation catalyzed by cytosolic sulfotransferase (SULT) enzymes. The SULTs are Phase II drug-metabolizing enzymes that catalyze the addition of a sulfuryl moiety to both endogenous compounds, including steroid...
TMPY-01813	ACRV1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Acrosomal protein SP-1, also known as Acrosomal vesicle protein 1 and ACRV1, is a testis-specific, differentiation antigen, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the a...
TMPY-04548	CDK4 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	CDK4 is a member of the Ser/Thr protein kinase family. It is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cel...
TMPH-00743	PhoP Protein, E. coli, Recombinant (HEK293, His & Myc)	E. coli	HEK293 Cells
	Member of the two-component regulatory system PhoP/PhoQ involved in adaptation to low Mg(2+) environments and the control of acid resistance genes. In low periplasmic Mg(2+), PhoQ phosphorylates PhoP, resulting in the ex...
TMPH-03487	DNA-binding protein H-NS Protein, SerRatia marcescens, Recombinant (His)	Serratia marcescens	E. coli
	A DNA-binding protein implicated in transcriptional repression and chromosome organization and compaction. Binds nucleation sites in AT-rich DNA and bridges them, forming higher-order nucleoprotein complexes and condensi...
TMPY-02488	HOXA1 Protein, Human, Recombinant (His)	Human	E. coli
	Homeobox protein Hox-A1 is a transcription factor encoded by the HOXA1 gene. This gene is one of the four types of homeobox genes each of which contains a homeobox DNA sequence that codes for the homeodomain, a region of...
TMPH-00729	RpoH Protein, E. coli, Recombinant (His & Myc)	E. coli	E. coli
	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. Intrac...
TMPH-00659	FlgM Protein, E. coli, Recombinant (His & Myc)	E. coli	E. coli
	Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar ...
TMPK-00401	FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region c...
TMPH-01090	CBX8 Protein, Human, Recombinant (His)	Human	E. coli
	Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex...
TMPJ-00752	HBAZ Protein, Human, Recombinant (His)	Human	E. coli
	Hemoglobin Subunit Zeta (HBZ) is a member of the Globin family. The zeta chain is an alpha-type chain of mammalian embryonic Hemoglobin that is synthesized primarily in the yolk sac of the early embryo, while alpha-globi...
TMPJ-01271	PIK3IP1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Phosphoinositide-3-kinase-interacting protein 1(PIK3IP1) is an enzyme that in humans is encoded by the PIK3IP1 gene.It is a negative regulator of phosphatidylinositol-3-kinase (PI3K), suppresses the development of hepato...
TMPJ-00854	ETS1 Protein, Human, Recombinant (His)	Human	E. coli
	ETS1 Protein (ETS1) is a nuclear protein that belongs to the ETS family. Members of this family recognize the core consensus DNA sequence GGAA/T in target genes. Proteins function either as transcriptional activators or ...
TMPH-01552	IRF1 Protein, Human, Recombinant (GST & His)	Human	Baculovirus Insect Cells
	Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. Regulates transcription of IFN and IFN-inducible genes, host response to viral and bacterial infections,...
TMPH-00077	IAA17 Protein, Arabidopsis thaliana, Recombinant (His & Myc)	Arabidopsis thaliana	E. coli
	Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response fac...
TMPK-01446	HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	MAGE-A1 belongs to the chromosome X-clustered genes of cancer-testis antigen family and is normally expressed in the human germ line but is also overexpressed in various tumors.
TMPH-02103	SRF Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). Together with ...
TMPK-01445	HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	MAGE-A1 belongs to the chromosome X-clustered genes of cancer-testis antigen family and is normally expressed in the human germ line but is also overexpressed in various tumors.
TMPK-00391	FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region con...
TMPH-00727	FliA Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.
TMPK-01444	HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	MAGE-A1 belongs to the chromosome X-clustered genes of cancer-testis antigen family and is normally expressed in the human germ line but is also overexpressed in various tumors.
TMPJ-00886	ATF1 Protein, Human, Recombinant (His)	Human	E. coli
	Cyclic AMP-dependent transcription factor ATF-1(ATF1) which contains 1 bZIP (basic-leucine zipper) domain and 1 KID (kinase-inducible) domain, belongs to the bZIP family. It influences cellular physiologic processes by r...
TMPH-01549	Interferon epsilon/IFNE Protein, Human, Recombinant (His)	Human	E. coli
	Type I interferon required for maintaining basal levels of IFN-regulated genes, including 2'-5'-oligoadenylate synthetase, IRF7 and ISG15, in the female reproductive tract. Directly mediates protection against viral and ...
TMPH-02321	GLI1 Protein, Human, Recombinant (His)	Human	E. coli
	Acts as a transcriptional activator. Binds to the DNA consensus sequence 5'-GACCACCCA-3'. Regulates the transcription of specific genes during normal development. Plays a role in craniofacial development and digital deve...
TMPY-03437	DNAJC30 Protein, Human, Recombinant (His)	Human	E. coli
	DNAJC30 is a member of the DNAJ molecular chaperone homology domain-containing protein family. DNAJC30 gene is deleted in williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes...
TMPH-01526	KMT2E Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Associates with chromatin regions downstream of transcriptional start sites of active genes and thus regulates gene transcription. Chromatin interaction is mediated via the binding to tri-methylated histone H3 at 'Lys-4'...
TMPY-03049	GALNT10 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Ectopic expression and knockdown studies showed that GALNT10 indeed promotes proliferation and apoptosis resistance of hepatoma cells in a glycosyltransferase-dependent manner. The genetic variants on LEKR1 and GALNT10 g...
TMPK-00584	BTN2A2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Butyrophilin (BTN) genes encode a set of related proteins. Cell surface BTN2A2 protein, such as the B7 family molecule programmed death ligand 1, was upregulated upon activation of T cells.BTN2A2 is a co-inhibitory molec...
------------------------ More ------------------------

CREG1 Protein, Human, Recombinant (His)

TMPY-05426

Species: Human

Expression System: HEK293 Cells

CREG1 Protein, Mouse, Recombinant (hFc)

TMPY-03559

Species: Mouse

Expression System: HEK293 Cells

CREG1 Protein, Mouse, Recombinant (His)

TMPY-03420

Species: Mouse

Expression System: HEK293 Cells

Sting Protein, Human, Recombinant (Sumo & His)

TMPJ-01206

Species: Human

Expression System: E. coli

CRISPR-Cas9 Protein, Streptococcus pyogenes, Recombinant (His)

TMPY-05346

Species: Streptococcus pyogenes

Expression System: Baculovirus Insect Cells

Flagellin Protein, Listeria monocytogenes, Recombinant (His)

TMPY-03465

Species: Listeria monocytogenes

Expression System: E. coli

Phosphinothricin N-acetyltransferase Protein, S. viridochromogenes, Recombinant (His)

TMPH-03608

Species: Streptomyces viridochromogenes

Expression System: P. pastoris (Yeast)

Streptopain Protein, S. pyogenes, Recombinant (His & SUMO)

TMPH-03599

Species: Streptococcus pyogenes

Expression System: E. coli

Phosphinothricin N-acetyltransferase Protein, S. viridochromogenes, Recombinant (His & SUMO)

TMPH-03609

Species: Streptomyces viridochromogenes

Expression System: E. coli

IdeS Protein, Streptococcus pyogenes, Recombinant (His & GST)

TMPY-06179

Species: Streptococcus pyogenes

Expression System: E. coli

Streptopain Protein, S. pyogenes serotype M28, Recombinant (His & SUMO)

TMPH-03598

Species: Streptococcus pyogenes

Expression System: E. coli

Exotoxin type A Protein, S. pyogenes, Recombinant (His & SUMO)

TMPH-03594

Species: Streptococcus pyogenes

Expression System: E. coli

Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (E. coli, His & Myc)

TMPH-03597

Species: Streptococcus pyogenes

Expression System: E. coli

IdeS Protein, Streptococcus pyogenes, Recombinant (His)

TMPY-06023

Species: Streptococcus pyogenes

Expression System: E. coli

APT Protein, S. pyogenes serotype M1, Recombinant (His & Myc)

TMPH-03595

Species: Streptococcus pyogenes

Expression System: P. pastoris (Yeast)

Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (His & Myc)

TMPH-03596

Species: Streptococcus pyogenes

Expression System: Baculovirus Insect Cells

Lysyl endopeptidase Protein, Lysobacter enzymogenes, Recombinant (His & SUMOstar)

TMPH-02415

Species: Lysobacter enzymogenes

Expression System: P. pastoris (Yeast)

Apolipoprotein A-IV/APOA4 Protein, Human, Recombinant (His)

TMPY-04310

Species: Human

Expression System: HEK293 Cells

TL1A/TNFSF15 Protein, Mouse, Recombinant

TMPJ-00603

Species: Mouse

Expression System: E. coli

FGF-4 Protein, Human, Recombinant

TMPY-05004

Species: Human

Expression System: E. coli

Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His)

TMPJ-01466

Species: Human

Expression System: HEK293 Cells

CD16a Protein, Human, Recombinant (F176V, His)

TMPY-01964

Species: Human

Expression System: HEK293 Cells

SULT1A1 Protein, Human, Recombinant (His)

TMPY-02062

Species: Human

Expression System: E. coli

ACRV1 Protein, Human, Recombinant (His)

TMPY-01813

Species: Human

Expression System: HEK293 Cells

CDK4 Protein, Human, Recombinant (GST)

TMPY-04548

Species: Human

Expression System: Baculovirus Insect Cells

PhoP Protein, E. coli, Recombinant (HEK293, His & Myc)

TMPH-00743

Species: E. coli

Expression System: HEK293 Cells

DNA-binding protein H-NS Protein, SerRatia marcescens, Recombinant (His)

TMPH-03487

Species: Serratia marcescens

Expression System: E. coli

HOXA1 Protein, Human, Recombinant (His)

TMPY-02488

Species: Human

Expression System: E. coli

RpoH Protein, E. coli, Recombinant (His & Myc)

TMPH-00729

Species: E. coli

Expression System: E. coli

FlgM Protein, E. coli, Recombinant (His & Myc)

TMPH-00659

Species: E. coli

Expression System: E. coli

FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00401

Species: Human

Expression System: HEK293 Cells

CBX8 Protein, Human, Recombinant (His)

TMPH-01090

Species: Human

Expression System: E. coli

HBAZ Protein, Human, Recombinant (His)

TMPJ-00752

Species: Human

Expression System: E. coli

PIK3IP1 Protein, Human, Recombinant (His)

TMPJ-01271

Species: Human

Expression System: HEK293 Cells

ETS1 Protein, Human, Recombinant (His)

TMPJ-00854

Species: Human

Expression System: E. coli

IRF1 Protein, Human, Recombinant (GST & His)

TMPH-01552

Species: Human

Expression System: Baculovirus Insect Cells

IAA17 Protein, Arabidopsis thaliana, Recombinant (His & Myc)

TMPH-00077

Species: Arabidopsis thaliana

Expression System: E. coli

HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Monomer Protein, Human, MHC (His & Avi)

TMPK-01446

Species: Human

Expression System: HEK293 Cells

SRF Protein, Human, Recombinant (His)

TMPH-02103

Species: Human

Expression System: P. pastoris (Yeast)

HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Monomer Protein, Human, MHC (His & Avi), Biotinylated

TMPK-01445

Species: Human

Expression System: HEK293 Cells

FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00391

Species: Human

Expression System: HEK293 Cells

FliA Protein, E. coli, Recombinant (His)

TMPH-00727

Species: E. coli

Expression System: E. coli

HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Tetramer Protein, Human, MHC (His & Avi)

TMPK-01444

Species: Human

Expression System: HEK293 Cells

ATF1 Protein, Human, Recombinant (His)

TMPJ-00886

Species: Human

Expression System: E. coli

Interferon epsilon/IFNE Protein, Human, Recombinant (His)

TMPH-01549

Species: Human

Expression System: E. coli

GLI1 Protein, Human, Recombinant (His)

TMPH-02321

Species: Human

Expression System: E. coli

DNAJC30 Protein, Human, Recombinant (His)

TMPY-03437

Species: Human

Expression System: E. coli

KMT2E Protein, Human, Recombinant (His & Myc)

TMPH-01526

Species: Human

Expression System: E. coli

GALNT10 Protein, Human, Recombinant (His)

TMPY-03049

Species: Human

Expression System: HEK293 Cells

BTN2A2 Protein, Mouse, Recombinant (His)

TMPK-00584

Species: Mouse

Expression System: HEK293 Cells

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カタログ番号	製品名
L7900	Osteogenesis Compound Library	317 compounds
	A unique collection of 317 osteogenesis related compounds for high throughput and high content screening;
L4800	Angiogenesis related Compound Library	1353 compounds
	A unique collection of 1353 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high throughput screening (HTS) and high content screening (HCS);
L1380	Transcription Factor-Targeted Compound Library	695 compounds
	Well-chosen 695 compounds with unique structures targeting transcription factor;
L3800	NF-κB Signaling Compound Library	729 compounds
	A unique collection of 729 compounds targeting NF-κB signaling for high throughput screening and high content screening;
L1510	Nuclear Receptor Compound Library	531 compounds
	A unique collection of 531 nuclear receptor signaling targeted compounds for high throughput and high content screening;
L8500	HIF-1 Signaling Pathway Compound Library	1336 compounds
	A unique collection of 1336 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies；
L3700	JAK-STAT Compound Library	252 compounds
	A unique collection of 252 JAK/STAT signaling targeted compounds for high throughput and high content screening;
L4100	TGF-beta/Smad Compound Library	184 compounds
	A unique collection of 184 TGF-beta/Smad signaling targeted compounds for high throughput and high content screening;
L8110	Reprogramming Compound Library	1813 compounds
	A unique collection of 1813 reprogramming signaling pathway-related bioactive small molecule compounds for high-throughput, high-content screening.
L9830	Anti-Parkinson's Disease Compound Library	857 compounds
	A unique collection of 857 compounds with anti-PD activities or acting on main drug targets of PD can be used for HTS and HCS.