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Search Results for " mRNA "

239

阻害剤

天然化合物

278

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T82494	EGFP mRNA-LNP
	eGFP mRNA-LNP is a lipid nanoparticle encapsulating eGFP mRNA, designed for assessments of RNA delivery, translation efficiency, and cell viability. The eGFP mRNA, once internalized by cells, expresses Enhanced Green Flu...
T75103	CD19 CAR mRNA
	CD19 CAR mRNA is designed to express the CD19 chimeric antigen receptor (CAR) protein, pivotal in chimeric antigen receptor T cell (CAR-CD19) immunotherapy. This receptor targets CD19, a membrane antigen crucial for B ce...
T75114	CD19 car mRNA-LNP
	CD19 car mRNA-LNP, a lipid nanoparticle (LNP) encapsulating CD19 car mRNA, is instrumental in assessing RNA delivery, translation efficacy, and cell viability among other applications. This compound is pivotal for chimer...
T75116	COVID-19 Spike Protein mRNA-LNP
	COVID-19 Spike Protein mRNA-LNP is a lipid nanoparticle (LNP) formulated with the novel coronavirus pneumonia spike protein, positioned on the membrane surface, designed for applications such as RNA delivery, translation...
T82495	EGFP mRNA(N1-Me-Pseudo UTP)
	eGFP mRNA encodes the green fluorescent protein, originally derived from the jellyfish Aequorea victoria, and serves as a widely utilized direct detection reporter in mammalian cell culture. This protein produces a disti...
T82397	Firefly Luciferase mRNA(N1-Me-Pseudo UTP)
	Firefly Luciferase mRNA, derived from Photinus pyralis (Firefly), codes for a bioluminescent enzyme widely utilized as a reporter in gene regulation and function analyses. This enzyme facilitates assays pertaining to gen...
T75102	COVID-19 Spike Protein mRNA(N1-Me-Pseudo UTP)
	The COVID-19 Spike Protein mRNA, responsible for expressing the COVID-19 spike protein, is crucial for evaluating RNA delivery, translation efficiency, and cell viability. Positioned on the membrane surface, this spike p...
T1481	Fudosteine		Others
	Fudosteine is a novel mucoactive agent and a MUC5AC mucin hypersecretion inhibitor.		Others
T35648	4-Thiouridine		Others
	4-Thiouridine (4-SU) is a photoactivatable ribonucleoside analog that is widely used for RNA analysis, including short-range RNA-RNA crosslinking and nascent RNA labeling. The crosslinking thio moiety is attached directl...		Others
T9410	SM-102		Others
	SM-102 is an ionizable amino lipid utilized in the synthesis of lipid nanoparticles (LNPs)[1]. It exhibits promise in the creation of LNPs dedicated to the transportation of mRNA-based vaccines[2].		Others
T7138	FB23-2		Apoptosis , Others
	FB23-2 is a potent and selective mRNA N6-methyladenosine (m6A) demethylase FTO inhibitor(IC50 : 2.6 μM).		Apoptosis , Others
T22089	HPI 1		Hedgehog/Smoothened
	HPI 1 is a hedgehog (Hh) signaling inhibitor. Inhibits Sonic hedgehog (Shh)-, SAG- and Gli-induced Hh pathway activation in Shh-LIGHT2 cells (IC50 values are 1.5, 1.5, 4, and 6 μM for Shh-, SAG-, Gli2- and Gli1-induced a...		Hedgehog/Smoothened
T16698	Pyronin Y	C.I. 45005,Pyronine G	Others
	Pyronin Y (Pyronine G) is an intercalating cationic dye that shows specificity towards RNA.		Others
T10760	Ceramides Mixture		Telomerase
	Ceramides Mixture, an endogenous ceramide, consists of hydroxy and non-hydroxy fatty acid-containing ceramides. It is involved in the regulation of cell cycle arrest, growth inhibition, and modulation of telomerase activ...		Telomerase
T8972	FIT-039		Others , DNA/RNA Synthesis , CDK , HSV
	FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1). FIT-039 inhibits replication of HSV-1 (IC50 of 0.69 μM), HSV-2, human adenovirus, and human CMV. FIT-039 is a pr...		Others , DNA/RNA Synthesis , CDK , HSV
T19459	N1-Methylpseudouridine	1-Methylpseudouridine	Others
	N1-Methylpseudouridine (1-Methylpseudouridine) is a methylpseudouridine and enhances translation through eIF2α-dependent and independent mechanisms by increasing ribosome density in mRNA.		Others
T0717L	Enoxacin	NSC 629661,AT 2266,Pd107779,CI 919	DNA/RNA Synthesis , Topoisomerase , Antibacterial , Antibiotic
	Enoxacin (NSC-629661) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.
T9854	HIV-1 inhibitor-6	3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-	HIV Protease
	HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicing inhibitor that blocks HIV replication.		HIV Protease
T0717	Enoxacin hydrate	CI-919 hydrate,Enoxacin Sesquihydrate,AT-2266 hydrate	DNA gyrase , DNA/RNA Synthesis , Topoisomerase , Antibacterial , Antibiotic
	Enoxacin hydrate (AT-2266 hydrate) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent.
T9033	BTYNB	MDK6620,BTYNB IMP1 Inhibitor	Others , c-Myc , NF-κB
	BTYNB (MDK6620) is an inhibitor of the oncofetal mRNA-binding protein IMP1 (IC50 = 5 μM for IMP1 binding to c-Myc mRNA). MDK6620 downregulates β-TrCP1 mRNA and reduces activation of nuclear transcriptional factors-kappa ...		Others , c-Myc , NF-κB
T16886	Sinefungin	Adenosyl-Ornithine,A-9145,Antibiotic 32232RP	Others , Histone Methyltransferase , Antibiotic , Antifungal
	Sinefungin (Adenosyl-Ornithine) is an effective inhibitor of virion mRNA(guanine-7-)-methyltransferase, mRNA(nucleoside-2'-)-methyltransferase, and viral multiplication. Sinefungin is a SET7/9 inhibitor and ameliorates r...
T9980	AVJ16		IGF-1R
	AVJ16 as a member of the insulin growth factor 2 mRNA-binding protein family, binds to the mRNA of certain genes to regulate protein translation.		IGF-1R
T17034	Temarotene	Ro 15-0778	Others
			Others
T38604	C12-200	C12-200	Others
	C12-200 is a benchmark ionizable cationic lipidoid along with helper lipids and can be used in the delivery of mRNA.		Others
T9640	Diethylnorspermine HCl	Diethylnorspermine tetrahydrochloride,N1,N11-Diethylnorspermine tetrahydrochloride,DENSPM tetrahydrochloride	Others
	Diethylnorspermine HCl (N1,N11-Diethylnorspermine tetrahydrochloride) potently induces SSAT (spermidine/spermine N1-acetyltransferase) mRNA and effectively stabilizes SSAT enzyme activity.		Others
T77945	TriGalNAc CBz		LYTACs
	TriGalNAc CBz is a GalNAc derivative. As an ASGPR ligand, tri-GalNAc targets lysosomes in mRNA drug delivery and LYTAC studies.L-DABA hydrobromide.		LYTACs
T16757	Risdiplam	RO7034067,RG7916	DNA/RNA Synthesis
	Risdiplam (RO7034067) (RG7916) is orally administered. Risdiplam is a centrally and peripherally distributed SMN2 pre-mRNA splicing modifier which increases survival motor neuron (SMN) protein levels[1].		DNA/RNA Synthesis
T14847	B I09		Others , IRE1
	B I09, an IRE-1 RNase inhibitor with an IC50 of 1230 nM, inhibits splicing of XBP1 mRNA in human WaC3 cells and expression of xbp-1 in LPS-stimulated B cells. B I09 can be used to simulate the defects of XBP-1 in CLL cel...		Others , IRE1
T4658	MHP	Methyl caprooyl tyrosinate	S1P Receptor
	MHP (Methyl caprooyl tyrosinate) is an activator of sphingosine kinase (SPHK1), and significantly stimulates CAMP mRNA and protein production in KC.		S1P Receptor
T9565	OSBPL7-IN-1		Others
	OSBPL7-IN-1 is an orally active inhibitor of oxysterol binding protein like 7 (OSBPL7). OSBPL7-IN-1 promotes an increase of ABCA1 at the plasma membrane without affecting mRNA expression[1].		Others
T21325	TAK-441	TAK441	Hedgehog/Smoothened
	TAK-441 is an orally active inhibitor of Hedgehog signaling(IC50 = 4.4 nM) with potent antitumor activity. TAK-441 suppresses transcription factor Gli1 mRNA expression and tumor growth.		Hedgehog/Smoothened
T16015	Maxacalcitol	22-Oxacalcitriol	Others
	Maxacalcitol (22-Oxacalcitriol) is a ligand of VDR-like receptors and a non-serum calcium vitamin D3 analogue. Maxacalcitol inhibits parathyroid hormone (PTH) mRNA expression in vitro and in vivo.		Others
TP2109L	AT 14 acetate		Nrf2
	TAT 14 acetate, a 14-mer peptide, is an Nrf2 activator with anti-inflammatory properties. TAT 14 acetate increases Nrf2 protein levels due to targeting the Nrf2 binding site on Keap1, but has no effect on Nrf2 mRNA expre...		Nrf2
T8874	FB23		Others
	FB23 directly binds to FTO and selectively inhibits FTO's m6A demethylase activity. (FTO, an mRNA N6-methyladenosine (m6A) demethylase, was reported to promote leukemogenesis.)		Others
T9277	ALC-0315
	ALC-0315 is an ionizable amino lipid that has been used in combination with other lipids to form lipid nanoparticles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine
T73475	SMN-C2		DNA/RNA Synthesis
	SMN-C2 is a selective regulator of SMN2 gene splicing, a risdiplam analogue, a selective RNA-binding ligand that regulates pre-mRNA splicing and acts by binding to SMN2 pre-mRNA.SMN-C2 has the potential to be used in the...		DNA/RNA Synthesis
T17181	TVB-3664		Fatty Acid Synthase
	TVB-3664 significantly decreases tubulin palmitoylation and mRNA expression. TVB-3664 is a reversible and highly bioavailable fatty acid synthase inhibitor (IC50: 18 nM and 12 nM for human and mouse cell palmitate synthe...		Fatty Acid Synthase
T3265	Azathramycin	Desmethyl Azithromycin,6-Demethylazithromycin,Azaerythromycin A,Azaerythromycin	Antibacterial , Antibiotic
	Azathramycin (Desmethyl Azithromycin) is an antibiotic derived from erythromycin, binding to the 50S subunit of the bacterial ribosome, and thus inhibits translation of mRNA.		Antibacterial , Antibiotic
T12781	RV01		Others
	RV01 is a novel quinoline-substituted analogue of resveratrol that inhibits DNA damage, reduces ethanol-induced acetaldehyde dehydrogenase (ALDH2) mRNA expression, and has hydroxyl radical scavenging activity. rV01 reduc...		Others
T67767	HIF-1 inhibitor-4	HIF-1 inhibitor-4	HIF
	HIF-1 inhibitor-4 (HIF-1 inhibitor-4) is a HIF-1 inhibitor with IC50 of 560 nM. HIF-1 inhibitor-4 reduces the HIF-1α protein level without affecting its mRNA level.		HIF
T3147	Pyrrolidinedithiocarbamate ammonium	PDTC,Pyrrolidinedithiocarbamate,APDC,1-Pyrrolidinedithiocarboxylic acid ammonium salt,Ammonium pyrrolidinedithiocarbamate	NF-κB
	Pyrrolidinedithiocarbamate ammonium (1-Pyrrolidinedithiocarboxylic acid ammonium salt), a selective NF-κB inhibitor, inhibits translation of nitric oxide synthase mRNA to prevent induction.		NF-κB
T13492	3,5-Diiodothyropropionic acid	C082182,Ditpa cpd	Thyroid hormone receptor(THR)
	3,5-Diiodothyropropionic acid (C082182) is a thyroid hormone analog. It induces α-myosin heavy chain mRNA expression, binds to thyroid hormone receptor (Ka: 2.40/M and 4.06/M for TRα1 and TRβ1).		Thyroid hormone receptor(THR)
T39965	NF-κΒ activator 1		NF-κB
	NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns. NF-κΒ is widely used in eukaryotic cells as a gene regulating cell proliferation and cell survival. NF-κΒ activator 1 induces superoxide ...		NF-κB
T60619	CDK9-IN-15		CDK
	CDK9-IN-15 is a potent small molecule CDK9 inhibitor, which can block the phosphorylation of positive transcription elongation factor b (P-TEFb) on the C-terminal region of RNA Poly-II by degradation and inhibition of CD...		CDK
T12574	PTC299	Emvododstat,(4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate	VEGFR , Dehydrogenase
	PTC299 ((4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate) is an orally active inhibitor of VEGFA mRNA translation and selectively inhibits VEGF protein synthesis at t...		VEGFR , Dehydrogenase
T27392	FT001		Epigenetic Reader Domain
	FT001 is a potent, selective and orally available inhibitor of BET Bromodomain with antitumor activity. FT001 inhibited the expression of MYC with the IC50 value of 0.46 μM). FT001 has potent antiproliferative effects ag...		Epigenetic Reader Domain
T3628	Madrasin	DDD00107587	DNA/RNA Synthesis
	Madrasin (DDD00107587) is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly.		DNA/RNA Synthesis
T14083	Abaperidone		Dopamine Receptor , 5-HT Receptor
	Abaperidone is a potent 5-HT2A receptor and dopamine D2 receptor antagonist with an IC50 of 6.2 for 5-HT2A receptors and 17 nM for dopamine D2 receptors.Abaperidone is a potentially atypical anti-psychotropic compound th...		Dopamine Receptor , 5-HT Receptor
T23897	CLK1/2-IN-3	CLK1/2 inhibitor 3,CLK1/2-inhibitor-3,CLK1/2 IN 3,CLK1/2IN3	CDK
	CLK1/2-IN-3 (Cpd-3) is a potent and selective CLK1 and CLK2 inhibitor with antiproliferative activity and inhibits the activities of CLK1, CLK2, SRPK1, SRPK2, and SRPK3.CLK1/2-IN-3 induces nuclear speckle enlargement, wh...		CDK
T16551	Pladienolide B		Apoptosis
	Pladienolide B is a potent spliceosome inhibitor, a macrolide isolated from Streptomyces obtusususus Mer-12, which targets the SF3B1 subunit of the spliceosome.Pladienolide B exerts its antitumor effects by inhibiting pr...		Apoptosis

Compounds

COVID-19 Spike Protein mRNA-LNP

T75116

Synonym:

Target:

eGFP mRNA(N1-Me-Pseudo UTP)

T82495

Synonym:

Target:

Firefly Luciferase mRNA(N1-Me-Pseudo UTP)

T82397

Synonym:

Target:

COVID-19 Spike Protein mRNA(N1-Me-Pseudo UTP)

Target: Apoptosis, Others

HPI 1

T22089

Synonym:

Target: Hedgehog/Smoothened

Pyronin Y

T16698

Synonym: C.I. 45005,Pyronine G

Target: Others, DNA/RNA Synthesis, CDK, HSV

N1-Methylpseudouridine

T19459

Synonym: 1-Methylpseudouridine

Target: Others

Enoxacin

T0717L

Synonym: NSC 629661,AT 2266,Pd107779,CI 919

Target: DNA/RNA Synthesis, Topoisomerase, Antibacterial, Antibiotic

HIV-1 inhibitor-6

T9854

Synonym: 3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-

Target: HIV Protease

Enoxacin hydrate

T0717

Synonym: CI-919 hydrate,Enoxacin Sesquihydrate,AT-2266 hydrate

Target: DNA gyrase, DNA/RNA Synthesis, Topoisomerase, Antibacterial, Antibiotic

BTYNB

T9033

Synonym: MDK6620,BTYNB IMP1 Inhibitor

Target: Others, c-Myc, NF-κB

Sinefungin

T16886

Synonym: Adenosyl-Ornithine,A-9145,Antibiotic 32232RP

Target: Others, Histone Methyltransferase, Antibiotic, Antifungal

Diethylnorspermine HCl

T9640

Synonym: Diethylnorspermine tetrahydrochloride,N1,N11-Diethylnorspermine tetrahydrochloride,DENSPM tetrahydrochloride

Synonym: RO7034067,RG7916

Target: DNA/RNA Synthesis

Synonym: Methyl caprooyl tyrosinate

Target: Hedgehog/Smoothened

Maxacalcitol

T16015

Synonym: 22-Oxacalcitriol

Target: DNA/RNA Synthesis

TVB-3664

T17181

Synonym:

Target: Fatty Acid Synthase

Azathramycin

T3265

Synonym: Desmethyl Azithromycin,6-Demethylazithromycin,Azaerythromycin A,Azaerythromycin

Target: Antibacterial, Antibiotic

Synonym: HIF-1 inhibitor-4

Target: HIF

Pyrrolidinedithiocarbamate ammonium

T3147

Synonym: PDTC,Pyrrolidinedithiocarbamate,APDC,1-Pyrrolidinedithiocarboxylic acid ammonium salt,Ammonium pyrrolidinedithiocarbamate

Target: NF-κB

3,5-Diiodothyropropionic acid

T13492

Synonym: C082182,Ditpa cpd

Target: Thyroid hormone receptor(THR)

Synonym: Emvododstat,(4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate

Target: VEGFR, Dehydrogenase

FT001

T27392

Synonym:

Target: Epigenetic Reader Domain

Madrasin

T3628

Synonym: DDD00107587

Target: DNA/RNA Synthesis

Abaperidone

T14083

Synonym:

Target: Dopamine Receptor, 5-HT Receptor

CLK1/2-IN-3

T23897

Synonym: CLK1/2 inhibitor 3,CLK1/2-inhibitor-3,CLK1/2 IN 3,CLK1/2IN3

カタログ番号	製品名	別名	ターゲット
T16674	Pseudouridine		Endogenous Metabolite
	Pseudouridine is the most abundant modified nucleoside in non-coding RNAs. It enhances the function of transfer RNA and ribosomal RNA by stabilizing RNA structure.		Endogenous Metabolite
T5S0246	Pseudoprotodioscin		Others , Fatty Acid Synthase
	1. Pseudoprotodioscin has moderate cytotoxicity.		Others , Fatty Acid Synthase
TQ0218	Deoxyandrographolide	14-deoxyandrographolide	IL Receptor , TNF
			IL Receptor , TNF
TN1465	Cannabigerol		NOS , 5-HT Receptor , ROS
	Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; also binds to the CB2 receptor; it can relieve interocular pressur...		NOS , 5-HT Receptor , ROS
T17143	Toyocamycin	Vengicide	Apoptosis , Others , IRE1 , Antibiotic , Antifungal
	Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM). Toyocamycin induces apoptosis.		Apoptosis , Others , IRE1 , Antibiotic , Antifungal
T2A2481	Taurochenodeoxycholic Acid	Chenodeoxycholyltaurine,TCDCA,Chenyltaurine,Taurochenodeoxycholate,12-Deoxycholyltaurine	Apoptosis , TNF , Caspase , Endogenous Metabolite
	Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.		Apoptosis , TNF , Caspase , Endogenous Metabolite
TN2215	Taurochenodeoxycholic acid sodium	Sodium taurochenodeoxycholate	Apoptosis , Endogenous Metabolite
	Taurochenodeoxycholic acid sodium (Sodium taurochenodeoxycholate) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid sodium induces apoptosis and shows obvious anti-inflammatory and...		Apoptosis , Endogenous Metabolite
TCS2170	2,5-Dihydroxyacetophenone	Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP	ERK , NF-κB , Tyrosinase
	1. 2,5-Dihydroxyacetophenone (Quinacetophenone) possess anti-anxiety, and neuroprotective qualities. 2. 2,5-Dihydroxyacetophenone (Quinacetophenone) reatment can induce a sustained activation of JNK, ERK1/2, and p38 MAPK...		ERK , NF-κB , Tyrosinase
TN2331	Eleutheroside B1		Influenza Virus
	Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits l...		Influenza Virus
T4S0181	Hinokiflavone		MMP , BCL , E1/E2/E3 Enzyme
	Hinokiflavone, a novel modulator of pre-mRNA splicing activity both in vitro and in cellulo, inhibits the assembly of the spliceosome, particularly blocking the formation of the B complex. Additionally, it acts as a SUMO...		MMP , BCL , E1/E2/E3 Enzyme
T5S1981	Alpha-Cyperone	(+)-α-Cyperone,α-Cyperone	Others , Endogenous Metabolite
	1. alpha-Cyperone (α-Cyperone) is a promising inhibitor of Hla production by S. aureus and protects lung cells from this bacterium. 2. alpha-Cyperone significantly inhibited PGE2 production by suppressing the LPS-induced...		Others , Endogenous Metabolite
T3809	Liriope muscari baily saponins C		Others
	Liriope muscari baily saponins C has an anti-thrombotic activity due to down-regulation of the increased mRNA expression levels of TF and IL-6.		Others
T21430	Oxytetracycline Hydrochloride	Biosolvomycin,Oxytetracycline HCl,Oxytetracycline.HCl,Dalimycin,Oxytetracycline, Sodium Salt,Dalinmycin	Antiviral , Endogenous Metabolite , Antibacterial , HSV
	Oxytetracycline Hydrochloride (Dalimycin) is a tetracycline derivative produced by Streptomyces rimosus with antimicrobial activity. It interferes with the binding of aminoacyl-tRNA to the mRNA-ribosome complex, resultin...		Antiviral , Endogenous Metabolite , Antibacterial , HSV
T6S2023	Harpagoside		Others , COX , NO Synthase
	1. Harpagoside has anti-inflammatory activity. 2. Harpagoside at 3 mM concentration, shows moderate inhibition of seed germination. 3. Harpagoside can inhibit lipopolysaccharide-induced mRNA levels and protein expression...		Others , COX , NO Synthase
T5727	CAFESTOL		ERK , NF-κB , COX , PGE Synthase
	CAFESTOL is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells. Cafestol has strong inhibitory activity on PGE2 production...		ERK , NF-κB , COX , PGE Synthase
T2S0410	Euphorbia factor L1	Euphorbiasteroid	Apoptosis , P-gp
	Euphorbia factor L1 (Euphorbiasteroid) can reduce Bcl-2, PI3K, AKT, and mTOR protein and mRNA levels, and up-regulate caspase-9 and caspase-3 protein levels. It induces autophagy and has anti-cancer, anti-adipogenic, ant...		Apoptosis , P-gp
T2845	Imperatorin	Ammidin,8-Isoamylenoxypsoralen,8-Isopentenyloxypsoralene,Marmelosin,Pentosalen	TRP/TRPV Channel , AChR , AChE , NOD
	Imperatorin (8-Isopentenyloxypsoralene) is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.		TRP/TRPV Channel , AChR , AChE , NOD
T6430	Calcifediol	U 32070E,25-hydroxy Vitamin D3,RO 8-8892	Endogenous Metabolite
	Calcifediol (U 32070E)(Ki of 3.9 μM), a major circulating metabolite of vitamin D3, works as a competitive inhibitor. It (ED50=2 nM)also inhibits PTH secretion and mRNA.		Endogenous Metabolite
T4S0795	Berberrubine chloride	9-Berberoline Chloride,Beroline,Beroline Chloride,Berberrubine,9-Berberoline	IL Receptor
	1. Berberrubine chloride (9-Berberoline Chloride) has antitumor activity. 2. Berberrubine has antidiabetic activity. 3. Berberrubine dose-dependently inhibits IL-8 and MCP-1 protein levels in the media and mRNA expressio...		IL Receptor
T1104	Paromomycin Sulfate	Aminosidine sulfate,Paromomycin sulfate salt	Antibacterial , Antibiotic , Parasite
	Paromomycin binds specifically to the RNA oligonucleotide at the A site of bacterial 30S ribosomes, thereby causing misreading and premature termination of translation of mRNA and inhibition of protein synthesis followed...		Antibacterial , Antibiotic , Parasite
T3889	Platycodin D		Prostaglandin Receptor , AMPK
	Platycodin D may stimulate TNF-α synthesis or inhibit degradation of TNF-α mRNA. Platycodin D (10/30 μM) suppresses prostaglandin E2 production in rat peritoneal macrophages stimulated by the protein kinase C activator 1...		Prostaglandin Receptor , AMPK
T3918	Ginsenoside Rb3	Gypenoside IV	NF-κB , COX , NO Synthase
	Ginsenoside Rb3 (Gypenoside IV) is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB transcriptional activity. It also inhibits the induction of COX-2 and iNOS mRNA.		NF-κB , COX , NO Synthase
TN2080	Pinoresinol	(+)-Pinoresinol	Apoptosis , NF-κB , CDK , p53
	Pinoresinol ((+)-Pinoresinol) has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury, to increase nitric oxide release and to reduce oxidative st...		Apoptosis , NF-κB , CDK , p53
T3S1701	Dihydrocurcumin		PPAR , Fatty Acid Synthase
	Dihydrocurcumin is the main metabolite of curcumin, which can reduce fat accumulation and oxidative stress response. Dihydrocurcumin can regulate the mRNA and protein expression levels of SREBP-1C, PNPLA3 and PPARα, incr...		PPAR , Fatty Acid Synthase
T3729	Ethyl gallate	Nipagallin A,Phyllemblin,gallic acid ethyl ester	MMP , NF-κB , Akt , Antibacterial
	Ethyl gallate (gallic acid ethyl ester) obviously decreases cell proliferation in MDA-MB-231 and MCF-7 cells in a dose- and time-dependent manner, exhibits cytotoxicity in a dose-dependent manner. Ethyl gallate can inhib...		MMP , NF-κB , Akt , Antibacterial
TMS1461	Qingyangshengenin B	Otophylloside B	Beta Amyloid
	Qingyangshengenin B (Otophylloside B) is a C-21 steroidal glycoside isolated from Qingyangshen. Qingyangshengenin B protects against Aβ toxicity, which decreases Aβ deposition by decreasing the expression of Aβ at the mR...		Beta Amyloid
T5S2228	6‴-Feruloylspinosin	6'''-Feruloylspinosin	NF-κB
	6‴-Feruloylspinosin (6'''-Feruloylspinosin) may possess anti-inflammatory activity.		NF-κB
TN2091	Polygalacin D		Apoptosis , IAP
	Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-induced iNOS and COX-2 protein and mRNA without an appreciable cytotoxi...		Apoptosis , IAP
T4S21320	ISOGINKGETIN	4',4'''-Dimethylamentoflavone	MMP , Others
	1. ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion with potency comparable to that of rosiglitazone, a known modulator of adiponecti...		MMP , Others
T3S0175	Gardenia yellow	alpha-Crocin,Crocin I,Crocine	Sirtuin
	Gardenia yellow (Crocin I) has anti atherosclerosis and hypolipidemic effects.		Sirtuin
TWO2727	Propane-1,2,3-triyl tripalmitate	Palmitic Triglyceride,Tripalmitin,Tripalmitoylglycerol,Glycerol Tripalmitate	Others , Endogenous Metabolite
	Propane-1,2,3-triyl tripalmitate (Glycerol Tripalmitate) is a triacylglycerol found in dietary fats. Tripalmitin increases body weight and plasma LDL levels and reduces hepatic LDL receptor mRNA levels in hamsters fed a ...		Others , Endogenous Metabolite
T0912	Tetracycline hydrochloride	NCI-c55561,Tetracycline HCl	ribosome , Antibacterial , Antibiotic
	Tetracycline hydrochloride (NCI-c55561) is the hydrochloride salt of the tetracycline, a broad-spectrum naphthacene antibiotic produced semisynthetically from chlortetracycline, an antibiotic isolated from the bacterium ...		ribosome , Antibacterial , Antibiotic
T6S1579	Monotropein	Monotropeine	Others
	1. Monotropein (Monotropeine) has antinociceptive action. 2. Monotropein has anti-apoptosis and anti-catabolic activity in chondrocytes. 3. Monotropein has anti-inflammatory action by inhibition of the expressions of inf...		Others
T2823	Crocin	Gardenia Yellow,Alpha-Crocin	Others
	Crocin (Gardenia Yellow) is a water-soluble carotenoid pigment of saffron (Crocus sativus L. ) that has been used as a spice for flavoring and coloring food preparations, and in Chinese traditional medicine as an anodyne...		Others
T5075	Phytic acid potassium	Inositol hexakisphosphate dipotassium salt,Phytic acid dipotassium salt,Fytic Acid dipotassium salt,Inositol polyphosphate dipotassium salt	Others , Endogenous Metabolite
	Phytic acid potassium (Inositol polyphosphate dipotassium salt) exists in all eukaryotic cells. In plants, it is known to function as a [PO4]3 storage depot and precursor for other inositol phosphates and pyrophosphates....		Others , Endogenous Metabolite
T5S0285	Cistanoside A		Others
	1. Cistanoside A possesses protective activities on CCl4 induced hepatotoxicity in mice, which is involved with increasing free radicals clearing activities, alleviating lipid-overoxidation damage, and improving respirat...		Others
T13818	Phytohemagglutinin	PHA-M	Apoptosis
	Phytohemagglutinin (PHA-M) is a lectin, isolated from the red kidney bean , induces apoptosis via increasing proapoptotic protein Bax and activating caspases-3. Anti-tumor activity		Apoptosis
T0683	Mevastatin	Compactin,ML236B	Apoptosis , Antibacterial , Antibiotic , HMG-CoA Reductase , Autophagy , Lipid
	Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum. Mevastatin was the first statin to enter clinical trials.
TN1291	7,3',4'-Tri-O-methylluteolin	5-Hydroxy-3',4',7-trimethoxyflavone	TNF , COX , Interleukin
	7,3',4'-Tri-O-methylluteolin (5-Hydroxy-3',4',7-trimethoxyflavone) has anti-inflammatory, antibacterial and antifungal activities, it also shows moderate antitrypanosomal activity with MIC value of 19.0 ug/ml		TNF , COX , Interleukin
T2762	Kasugamycin hydrochloride	Kasumin	Antibacterial , Antibiotic , Antifungal
	Kasugamycin hydrochloride (Kasumin) is an aminoglycoside antibiotic that was originally isolated in 1965, from Streptomyces kasugaensis, a Streptomyces strain found near the Kasuga shrine in Nara, Japan. Kasugamycin hydr...		Antibacterial , Antibiotic , Antifungal
T7030	Anemarsaponin B		p38 MAPK , NF-κB , MEK , COX , NO Synthase
	Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activity, possibly via the p38 MAP kinase pathway. Anemarsaponin B c...		p38 MAPK , NF-κB , MEK , COX , NO Synthase
T4S1469	Cucurbitacin IIb		Apoptosis , Others
	1. Cucurbitacin IIb is one of the major active compounds in Hemsleyadine tablets which have been used for clinical treatment of bacillary dysentery, enteritis and acute tonsilitis. 2. Cucurbitacin IIb exhibits its anti-i...		Apoptosis , Others
T6S1487	Ginsenoside Rg5		NF-κB , COX , IGF-1R
	1. Ginsenoside Rg5 could be a beneficial agent for the treatment of Alzheimer's disease. 2. Ginsenoside Rg5 suppresses LPS-induced nitric oxide (NO) production and proinflammatory TNF-α secretion. 3. Ginsenoside Rg5 can ...		NF-κB , COX , IGF-1R
TN3614	Cearoin		ERK , BCL , PARP , IκB/IKK , TNF , NF-κB , ROS , Caspase
	Cearoin has anti-inflammatory, and antiallergic activities, it can markedly inhibit inflammatory responses including LPS-induced NO production by suppressing the expression of iNOS mRNA and LPS-induced mRNA expression of...		ERK , BCL , PARP , IκB/IKK , TNF , NF-κB , ROS , Caspase
T30048	Anemonin (6CI)	Pulsatilla camphor,Anemonin,Anemone camphor
	Anemonin is a furanone dimer found in the Buttercup (Ranunculaceae) family. Anemonin has been shown to regulate tyrosinase-related proteins and mRNA in human melanocytes and may be useful in attenuting osteoarthritis pro...
TN4446	Longiferone B		NOS , COX
	Longiferone B shows anti-inflammatory activity against NO release with IC50 values of 21.0 uM, it also suppresses the iNOS and COX-2 mRNA expression.		NOS , COX
T38890	Thailanstatin C
	Thailanstatin C, an antiproliferative agent derived from Burkholderia thailandensis MSMB43, functions as a potent inhibitor of pre-mRNA splicing (IC50 = 6.84 μM).
T27191	D-Mannuronic Acid
	D-Mannuronic Acid is a blocker of the TLR2 and TLR4 downstream signaling pathway. D-Mannuronic Acid effectively inhibits mRNA expression of MyD88 and p65, major subunit of nuclear factor-kappaB.
T77289	5-O-Methylembelin
	5-O-Methylembelin is a natural isocoumarin that inhibits PCSK9 , low-density lipoprotein receptor (IDOL) , and sterol regulatory element binding protein 2 (SREBP2) mRNA expression [1] .
T40368	4-Ethylresorcinol
	4-Ethylresorcinol, a derivative of resorcinol, functions as a tyrosinase substrate, possesses hypopigmentary effects, attenuates mRNA and protein expression of tyrosinase-related protein-2 (TRP-2), and exhibits antioxida...
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天然物製品

Pseudouridine

T16674

Synonym:

Target: Endogenous Metabolite

Pseudoprotodioscin

T5S0246

Synonym:

Target: Others, Fatty Acid Synthase

Deoxyandrographolide

TQ0218

Synonym: 14-deoxyandrographolide

Target: IL Receptor, TNF

Cannabigerol

TN1465

Synonym:

Target: NOS, 5-HT Receptor, ROS

Toyocamycin

T17143

Synonym: Vengicide

Target: Apoptosis, Others, IRE1, Antibiotic, Antifungal

Taurochenodeoxycholic Acid

T2A2481

Synonym: Chenodeoxycholyltaurine,TCDCA,Chenyltaurine,Taurochenodeoxycholate,12-Deoxycholyltaurine

Target: Apoptosis, TNF, Caspase, Endogenous Metabolite

Taurochenodeoxycholic acid sodium

TN2215

Synonym: Sodium taurochenodeoxycholate

Target: Apoptosis, Endogenous Metabolite

2,5-Dihydroxyacetophenone

TCS2170

Synonym: Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP

Target: ERK, NF-κB, Tyrosinase

Eleutheroside B1

TN2331

Synonym:

Target: Influenza Virus

Hinokiflavone

T4S0181

Synonym:

Target: MMP, BCL, E1/E2/E3 Enzyme

alpha-Cyperone

T5S1981

Synonym: (+)-α-Cyperone,α-Cyperone

Target: Others, Endogenous Metabolite

Liriope muscari baily saponins C

T3809

Synonym:

Target: Others

Oxytetracycline Hydrochloride

T21430

Synonym: Biosolvomycin,Oxytetracycline HCl,Oxytetracycline.HCl,Dalimycin,Oxytetracycline, Sodium Salt,Dalinmycin

Target: Antiviral, Endogenous Metabolite, Antibacterial, HSV

Harpagoside

T6S2023

Synonym:

Target: Others, COX, NO Synthase

CAFESTOL

T5727

Synonym:

Target: ERK, NF-κB, COX, PGE Synthase

Euphorbia factor L1

T2S0410

Synonym: Euphorbiasteroid

Target: Apoptosis, P-gp

Imperatorin

T2845

Synonym: Ammidin,8-Isoamylenoxypsoralen,8-Isopentenyloxypsoralene,Marmelosin,Pentosalen

Target: TRP/TRPV Channel, AChR, AChE, NOD

Calcifediol

T6430

Synonym: U 32070E,25-hydroxy Vitamin D3,RO 8-8892

Target: Endogenous Metabolite

Berberrubine chloride

T4S0795

Synonym: 9-Berberoline Chloride,Beroline,Beroline Chloride,Berberrubine,9-Berberoline

Target: IL Receptor

Paromomycin Sulfate

T1104

Synonym: Aminosidine sulfate,Paromomycin sulfate salt

Target: Antibacterial, Antibiotic, Parasite

Platycodin D

T3889

Synonym:

Target: Prostaglandin Receptor, AMPK

Ginsenoside Rb3

T3918

Synonym: Gypenoside IV

Target: NF-κB, COX, NO Synthase

Pinoresinol

TN2080

Synonym: (+)-Pinoresinol

Target: Apoptosis, NF-κB, CDK, p53

Dihydrocurcumin

T3S1701

Synonym:

Target: PPAR, Fatty Acid Synthase

Ethyl gallate

T3729

Synonym: Nipagallin A,Phyllemblin,gallic acid ethyl ester

Target: MMP, NF-κB, Akt, Antibacterial

Qingyangshengenin B

TMS1461

Synonym: Otophylloside B

Target: Beta Amyloid

6‴-Feruloylspinosin

T5S2228

Synonym: 6'''-Feruloylspinosin

Target: Apoptosis, IAP

ISOGINKGETIN

T4S21320

Synonym: 4',4'''-Dimethylamentoflavone

Target: MMP, Others

Gardenia yellow

T3S0175

Synonym: alpha-Crocin,Crocin I,Crocine

Target: Sirtuin

Propane-1,2,3-triyl tripalmitate

TWO2727

Synonym: Palmitic Triglyceride,Tripalmitin,Tripalmitoylglycerol,Glycerol Tripalmitate

Target: Others, Endogenous Metabolite

Tetracycline hydrochloride

T0912

Synonym: NCI-c55561,Tetracycline HCl

Target: ribosome, Antibacterial, Antibiotic

Monotropein

T6S1579

Synonym: Monotropeine

Target: Others

Crocin

T2823

Synonym: Gardenia Yellow,Alpha-Crocin

Target: Others

Phytic acid potassium

T5075

Synonym: Inositol hexakisphosphate dipotassium salt,Phytic acid dipotassium salt,Fytic Acid dipotassium salt,Inositol polyphosphate dipotassium salt

Target: Others, Endogenous Metabolite

Synonym: Compactin,ML236B

Target: Apoptosis, Antibacterial, Antibiotic, HMG-CoA Reductase, Autophagy, Lipid

7,3',4'-Tri-O-methylluteolin

TN1291

Synonym: 5-Hydroxy-3',4',7-trimethoxyflavone

Target: TNF, COX, Interleukin

Kasugamycin hydrochloride

T2762

Synonym: Kasumin

Target: Antibacterial, Antibiotic, Antifungal

anemarsaponin B

T7030

Synonym:

Target: p38 MAPK, NF-κB, MEK, COX, NO Synthase

Cucurbitacin IIb

T4S1469

Synonym:

Target: Apoptosis, Others

Ginsenoside Rg5

T6S1487

Synonym:

Target: NF-κB, COX, IGF-1R

Cearoin

TN3614

Synonym:

Target: ERK, BCL, PARP, IκB/IKK, TNF, NF-κB, ROS, Caspase

Anemonin (6CI)

T30048

Synonym: Pulsatilla camphor,Anemonin,Anemone camphor

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPK-01308	TAG-72 Protein, Canine, Recombinant (His)	Canine	E. coli
	The guanine-N7 methyltransferase domain of vaccinia virus mRNA capping enzyme is a heterodimer composed of a catalytic subunit and a stimulatory subunit. Cap (guanine-N7) methylation is an essential step in eukaryal mRNA...
TMPH-01631	DCP2 Protein, Human, Recombinant (His)	Human	E. coli
	Decapping metalloenzyme that catalyzes the cleavage of the cap structure on mRNAs. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Necessary for the ...
TMPY-03390	LSM1 Protein, Human, Recombinant (His)	Human	E. coli
	LSM1 is an Sm-like protein. Sm-like proteins can be detected in a variety of organisms based on sequence homology with the Sm protein family. Sm-like proteins include the Sm sequence motif, which consists of two regions ...
TMPJ-00345	IGF2BP-2 Protein, Human, Recombinant (His)	Human	E. coli
	Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 (IGFBP2) belongs to the RRM IMP/VICKZ family. IGFBP2 is a cytoplasmic protein and contains four KH domains and two RRM (RNA recognition motif) domains. IGF2BP2 binds to...
TMPY-03599	RPRD1B Protein, Human, Recombinant (His)	Human	HEK293
	RPRD1B, together with RPRD1A, can accompany RNAP II from promoter regions to 3'-untranslated regions during transcription in vivo, predominantly interact with phosphorylated RNAP II, and can reduce CTD S5- and S7-phospho...
TMPH-03432	ACC1 Protein, S. cerevisiae, Recombinant (aa 2-581, His)	Saccharomyces cerevisiae	E. coli
	Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nucle...
TMPH-03431	ACC1 Protein, S. cerevisiae, Recombinant (aa 217-775, His)	Saccharomyces cerevisiae	E. coli
	Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nucle...
TMPY-01762	IGF2BP-2 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is a member of the IGF-II mRNA-binding protein (IMP) family. IGF2BP2 is a member of a family of mRNA binding proteins that, collectively, have been shown to b...
TMPH-01457	Human herpesvirus 6B (HHV-6 variant B) (strain Z29) mRNA export factor ICP27 homolog (His & Myc)	HHV-6B	E. coli
	Human herpesvirus 6B (HHV-6 variant B) (strain Z29) mRNA export factor ICP27 homolog (His & Myc) is expressed in E. coli.
TMPJ-00507	EIF4E Protein, Human, Recombinant	Human	E. coli
	Eukaryotic translation initiation factor 4E is a 217 amino acids protein that belongs to the eukaryotic initiation factor 4E family. eIF4F is a multi-subunit complex, the composition of which varies with external and int...
TMPH-03712	Clp1 Protein, Xenopus laevis, Recombinant (His)	Xenopus laevis	E. coli
	Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated mo...
TMPJ-00705	BCAS2 Protein, Human, Recombinant (His, T7)	Human	E. coli
	Breast Carcinoma-Amplified Sequence 2 (BCAS2) is a member of the SPF27 family. BCAS2 is a nuclear protein and widely expressed in many rtissues. BCAS2 is identified as being overexpressed in various breast cancer cell li...
TMPJ-00712	MPZL1 Protein, Human, Recombinant (His)	Human	Human Cells
	Myelin protein zero-like protein 1(MPZL1) is encoded by the MPZL1 gene, which is a single-pass type I membrane protein. It is widely expressed with highest levels in heart, placenta, kidney and pancreas. As cell surface ...
TMPJ-00651	CD155/PVR Protein, Human, Recombinant (aa 21-343, His)	Human	Human Cells
	Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entr...
TMPJ-00154	IL-15RA Protein, Mouse, Recombinant (hFc, Human Cells)	Mouse	Human Cells
	Mouse interleukin-15 receptor subunit alpha, also known as Il15ra, is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits (Common gamma chain, o...
TMPY-01395	CTHRC1 Protein, Human, Recombinant (His)	Human	HEK293
	Collagen triple helix repeat-containing protein 1, also known as Protein NMTC1, and CTHRC1, is a secreted protein that is glycosylated and highly conserved from lower chordates to mammals. CTHRC1 expression was not detec...
TMPY-04298	CDCP1 Protein, Human, Recombinant (His)	Human	HEK293
	CDCP1 contains three extracellular CUB domains. It is a putative stem cell marker that is highly expressed in some human cancer cells and both, typical and atypical (cancerous) colons. It interacts with CDH2/N-cadherin, ...
TMPY-02667	TROP-2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	TROP-2, also referred to as tumor-associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1, is a cell surface glycoprotein highly expressed in a wide variety of epithelial cancers. In contrast, there is little o...
TMPY-05153	TROP-2 Protein, Cynomolgus, Rhesus, Recombinant (His)	Cynomolgus,Rhesus	HEK293
	TROP-2, also referred to as tumor-associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1, is a cell surface glycoprotein highly expressed in a wide variety of epithelial cancers. In contrast, there is little o...
TMPY-01262	TROP-2 Protein, Human, Recombinant (His)	Human	HEK293
	TROP-2, also referred to as tumor-associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1, is a cell surface glycoprotein highly expressed in a wide variety of epithelial cancers. In contrast, there is little o...
TMPY-00908	Renin Protein, Human, Recombinant (His)	Human	HEK293
	Renin-1, also known as Ren-1, Angiotensinogenase and Kidney renin, is a member of the peptidase A1 family. Renin-1 is synthesized by the juxtaglomerular cells of the kidney in response to decreased blood pressure and sod...
TMPY-03835	CDCP1 Protein, Rhesus, Recombinant (His)	Rhesus	HEK293
	CDCP1 contains three extracellular CUB domains. It is a putative stem cell marker that is highly expressed in some human cancer cells and both, typical and atypical (cancerous) colons. It interacts with CDH2/N-cadherin, ...
TMPY-01694	Clusterin Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Clusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted prot...
TMPY-01691	Clusterin Protein, Human, Recombinant (CLU34, His)	Human	HEK293
	Clusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted prot...
TMPY-00836	IGFBP-4 Protein, Human, Recombinant (His)	Human	HEK293
	Insulin-like growth factor-binding protein 4 (IGFBP-4) is a 24-kDa protein that binds insulin-like growth factor 1 (IGF-1) and IGF-2 with high affinity and inhibits IGF action in vitro. The Insulin-like growth factor-bin...
TMPY-04376	PLK1 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Serine / threonine-protein kinase PLK1 / PLK-1, also known as polo-like kinase 1 (PLK-1) or serine / threonine-protein kinase 13 (STPK13), Polo-like kinases (PLKs), is a family of four serine / threonine protein kinases ...
TMPY-01047	IL-1R1 Protein, Human, Recombinant (hFc)	Human	HEK293
	Interleukin 1 receptor, type I (IL-1R1) also known as CD121a (Cluster of Differentiation 121a), is an interleukin receptor. IL-1R1/CD121a is a cytokine receptor that belongs to the interleukin 1 receptor family. This pro...
TMPY-02130	Argonaute-2 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus-Insect Cells
	Argonaute 2 (AGO2), also known as Eukaryotic translation initiation factor 2C2 (EIF2C2), belongs to the Argonaute family, AGO subfamily, which is a component of the RNA-induced silencing complex (RISC) and mediates small...
TMPY-00803	Fibronectin Protein, Human, Recombinant (aa 607-1265, His)	Human	HEK293
	Fibronectin (FN) is a glycoprotein component of the extracellular matrix of the extracellular matrix (ECM) with roles in embryogenesis, development, and wound healing. More recently, FN has emerged as player in platelet ...
TMPY-01848	HMGB1 Protein, Human, Recombinant (aa 1-215, His)	Human	HEK293
	High-mobility group box 1 protein (HMGB1), also known as HMG-1 or amphoterin previously, is a member of the HMGB family consisting of three members, HMGB1, HMGB2, and HMGB3. HMGB1 is a DNA-binding nuclear protein, releas...
TMPY-02590	HMGB1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	High-mobility group box 1 protein (HMGB1), also known as HMG-1 or amphoterin previously, is a member of the HMGB family consisting of three members, HMGB1, HMGB2, and HMGB3. HMGB1 is a DNA-binding nuclear protein, releas...
TMPY-04483	IRAK4 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Interleukin-1 receptor-associated kinase 4, also known as Renal carcinoma antigen NY-REN-64, IRAK-4, and IRAK4, is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, and Pelle subfamily. IRAK4...
TMPY-01186	Argonaute-2 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Argonaute 2 (AGO2), also known as Eukaryotic translation initiation factor 2C2 (EIF2C2), belongs to the Argonaute family, AGO subfamily, which is a component of the RNA-induced silencing complex (RISC) and mediates small...
TMPY-01253	LAMP1 Protein, Human, Recombinant (His)	Human	HEK293
	Lysosome-associated membrane glycoprotein 1, also known as CD107 antigen-like family member A, CD107a, and LAMP1, is a single-pass type I membrane protein that belongs to the LAMP family. CD107a is expressed largely in t...
TMPH-01282	ELAVL4 Protein, Human, Recombinant (His & Myc & SUMO)	Human	E. coli
	RNA-binding protein that is involved in the post-transcriptional regulation of mRNAs. Plays a role in the regulation of mRNA stability, alternative splicing and translation. Binds to AU-rich element (ARE) sequences in th...
TMPH-02883	RBFOX3 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Pre-mRNA alternative splicing regulator. Regulates alternative splicing of RBFOX2 to enhance the production of mRNA species that are targeted for nonsense-mediated decay (NMD).
TMPH-01786	NCBP1 Protein, Human, Recombinant (His & Myc)	Human	Baculovirus
	Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay,...
TMPH-01785	NCBP1 Protein, Human, Recombinant (E. coli, His & Myc)	Human	E. coli
	Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay,...
TMPH-00303	SF3B3 Protein, Bovine, Recombinant (His)	Bovine	E. coli
	Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branch...
TMPH-01312	EIF4G1 Protein, Human, Recombinant (B2M & His & JD & Myc)	Human	E. coli
	Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. As a member of the eIF4F c...
TMPH-01885	PABPC1 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Binds the poly(A) tail of mRNA, including that of its own transcript, and regulates processes of mRNA metabolism such as pre-mRNA splicing and mRNA stability. Its function in translational initiation regulation can eithe...
TMPH-02976	YBX1 Protein, Mouse, Recombinant (His)	Mouse	Yeast
	DNA- and RNA-binding protein involved in various processes, such as translational repression, RNA stabilization, mRNA splicing, DNA repair and transcription regulation. Predominantly acts as a RNA-binding protein: binds ...
TMPH-01787	NCBP2 Protein, Human, Recombinant (GST)	Human	E. coli
	Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay...
TMPH-01313	EIF4G1 Protein, Human, Recombinant (His)	Human	Yeast
	Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. As a member of the eIF4F c...
TMPH-02228	TRA2B Protein, Human, Recombinant (His & Myc)	Human	Baculovirus
	Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor ne...
TMPH-00744	CsrA Protein, E. coli, Recombinant	E. coli	E. coli
	A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress...
TMPH-01281	ELAVL3 Protein, Human, Recombinant (His)	Human	Yeast
	RNA-binding protein that binds to AU-rich element (ARE) sequences of target mRNAs, including VEGF mRNA. May also bind poly-A tracts via RRM 3. May be involved in neuronal differentiation and maintenance. Plays a role in ...
TMPH-02133	DDX39B Protein, Human, Recombinant (GST)	Human	E. coli
	Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mR...
TMPH-03444	GCY1 Protein, S. cerevisiae, Recombinant (His)	Saccharomyces cerevisiae	Yeast
	Glycerol dehydrogenase involved in glycerol catabolism under microaerobic conditions. Has mRNA binding activity.
TMPH-02229	TRA2B Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor ne...
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TAG-72 Protein, Canine, Recombinant (His)

TMPK-01308

Species: Canine

Expression System: E. coli

DCP2 Protein, Human, Recombinant (His)

TMPH-01631

Species: Human

Expression System: E. coli

LSM1 Protein, Human, Recombinant (His)

TMPY-03390

Species: Human

Expression System: E. coli

IGF2BP-2 Protein, Human, Recombinant (His)

TMPJ-00345

Species: Human

Expression System: E. coli

RPRD1B Protein, Human, Recombinant (His)

TMPY-03599

Species: Human

Expression System: HEK293

ACC1 Protein, S. cerevisiae, Recombinant (aa 2-581, His)

TMPH-03432

Species: Saccharomyces cerevisiae

Expression System: E. coli

ACC1 Protein, S. cerevisiae, Recombinant (aa 217-775, His)

TMPH-03431

Species: Saccharomyces cerevisiae

Expression System: E. coli

IGF2BP-2 Protein, Human, Recombinant (His & GST)

TMPY-01762

Species: Human

Expression System: Baculovirus-Insect Cells

Human herpesvirus 6B (HHV-6 variant B) (strain Z29) mRNA export factor ICP27 homolog (His & Myc)

TMPH-01457

Species: HHV-6B

Expression System: E. coli

EIF4E Protein, Human, Recombinant

TMPJ-00507

Species: Human

Expression System: E. coli

Clp1 Protein, Xenopus laevis, Recombinant (His)

TMPH-03712

Species: Xenopus laevis

Expression System: E. coli

BCAS2 Protein, Human, Recombinant (His, T7)

TMPJ-00705

Species: Human

Expression System: E. coli

MPZL1 Protein, Human, Recombinant (His)

TMPJ-00712

Species: Human

Expression System: Human Cells

CD155/PVR Protein, Human, Recombinant (aa 21-343, His)

TMPJ-00651

Species: Human

Expression System: Human Cells

IL-15RA Protein, Mouse, Recombinant (hFc, Human Cells)

TMPJ-00154

Species: Mouse

Expression System: Human Cells

CTHRC1 Protein, Human, Recombinant (His)

TMPY-01395

Species: Human

Expression System: HEK293

CDCP1 Protein, Human, Recombinant (His)

TMPY-04298

Species: Human

Expression System: HEK293

TROP-2 Protein, Mouse, Recombinant (His)

TMPY-02667

Species: Mouse

Expression System: HEK293

TROP-2 Protein, Cynomolgus, Rhesus, Recombinant (His)

TMPY-05153

Species: Cynomolgus,Rhesus

Expression System: HEK293

TROP-2 Protein, Human, Recombinant (His)

TMPY-01262

Species: Human

Expression System: HEK293

Renin Protein, Human, Recombinant (His)

TMPY-00908

Species: Human

Expression System: HEK293

CDCP1 Protein, Rhesus, Recombinant (His)

TMPY-03835

Species: Rhesus

Expression System: HEK293

Clusterin Protein, Mouse, Recombinant (His)

TMPY-01694

Species: Mouse

Expression System: HEK293

Clusterin Protein, Human, Recombinant (CLU34, His)

TMPY-01691

Species: Human

Expression System: HEK293

IGFBP-4 Protein, Human, Recombinant (His)

TMPY-00836

Species: Human

Expression System: HEK293

PLK1 Protein, Human, Recombinant (His)

TMPY-04376

Species: Human

Expression System: Baculovirus-Insect Cells

IL-1R1 Protein, Human, Recombinant (hFc)

TMPY-01047

Species: Human

Expression System: HEK293

Argonaute-2 Protein, Mouse, Recombinant (His)

TMPY-02130

Species: Mouse

Expression System: Baculovirus-Insect Cells

Fibronectin Protein, Human, Recombinant (aa 607-1265, His)

TMPY-00803

Species: Human

Expression System: HEK293

HMGB1 Protein, Human, Recombinant (aa 1-215, His)

TMPY-01848

Species: Human

Expression System: HEK293

HMGB1 Protein, Mouse, Recombinant (hFc)

TMPY-02590

Species: Mouse

Expression System: HEK293

IRAK4 Protein, Human, Recombinant (His)

TMPY-04483

Species: Human

Expression System: Baculovirus-Insect Cells

Argonaute-2 Protein, Human, Recombinant (His)

TMPY-01186

Species: Human

Expression System: Baculovirus-Insect Cells

LAMP1 Protein, Human, Recombinant (His)

TMPY-01253

Species: Human

Expression System: HEK293

ELAVL4 Protein, Human, Recombinant (His & Myc & SUMO)

TMPH-01282

Species: Human

Expression System: E. coli

RBFOX3 Protein, Mouse, Recombinant (His & Myc)

TMPH-02883

Species: Mouse

Expression System: E. coli

NCBP1 Protein, Human, Recombinant (His & Myc)

TMPH-01786

Species: Human

Expression System: Baculovirus

NCBP1 Protein, Human, Recombinant (E. coli, His & Myc)

TMPH-01785

Species: Human

Expression System: E. coli

SF3B3 Protein, Bovine, Recombinant (His)

TMPH-00303

Species: Bovine

Expression System: E. coli

EIF4G1 Protein, Human, Recombinant (B2M & His & JD & Myc)

TMPH-01312

Species: Human

Expression System: E. coli

PABPC1 Protein, Human, Recombinant (His & SUMO)

TMPH-01885

Species: Human

Expression System: E. coli

YBX1 Protein, Mouse, Recombinant (His)

TMPH-02976

Species: Mouse

Expression System: Yeast

NCBP2 Protein, Human, Recombinant (GST)

TMPH-01787

Species: Human

Expression System: E. coli

EIF4G1 Protein, Human, Recombinant (His)

TMPH-01313

Species: Human

Expression System: Yeast

TRA2B Protein, Human, Recombinant (His & Myc)

TMPH-02228

Species: Human

Expression System: Baculovirus

CsrA Protein, E. coli, Recombinant

TMPH-00744

Species: E. coli

Expression System: E. coli

ELAVL3 Protein, Human, Recombinant (His)

TMPH-01281

Species: Human

Expression System: Yeast

DDX39B Protein, Human, Recombinant (GST)

TMPH-02133

Species: Human

Expression System: E. coli

GCY1 Protein, S. cerevisiae, Recombinant (His)

TMPH-03444

Species: Saccharomyces cerevisiae

Expression System: Yeast

TRA2B Protein, Human, Recombinant (His & SUMO)

TMPH-02229

Species: Human

Expression System: E. coli

--------- More ---------

カタログ番号	製品名
L9420	Exosome Compound Library	76 compounds
	76 exosome-related compounds that can be used for high-throughput and high-content screening.
L3800	NF-κB Signaling Compound Library	729 compounds
	A unique collection of 729 compounds targeting NF-κB signaling for high throughput screening and high content screening;

ライブラリー

Exosome Compound Library

L9420

Compounds: 76

NF-κB Signaling Compound Library

L3800

Compounds: 729