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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T1621 | Imatinib Mesylate | ST-1571 Mesylate,STI-571,CGP-57148B | Bcr-Abl , PDGFR , c-Kit , Autophagy |
Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR, respectively). | |||
T82613 | Danburstotug | STI-3031,IMC-001 | PD-1/PD-L1 |
Danburstotug (IMC-001), an immunostimulant and antineoplastic [1], is a humanized IgG1-lambda monoclonal antibody targeting CD274 (PDL1, B7 homologue 1, B7H1). | |||
T80581 | Plutavimab | COVI-AMG,STI-2020 | SARS-CoV |
Plutavimab is a humanized IgG1-κ monoclonal antibody targeting the receptor binding domain (RBD) of the SARS-CoV-2 spike (S) glycoprotein [1] [2]. | |||
T21319 | Gimatecan | LBQ707,STI481 | Topoisomerase |
Gimatecan (STI481) is a potent topoisomerase I inhibitor. Gimatecan is an orally bioavailable camptothecin analogue with antitumor activity. | |||
T6230 | Imatinib | STI571,CGP057148B,ST-1571 | SARS-CoV , Bcr-Abl , PDGFR , c-Kit , Autophagy |
Imatinib (STI571) is a multi-targeted receptor tyrosine kinase inhibitor that selectively inhibits the kinase activities of BCR/ABL, v-Abl, PDGFR, and c-kit with oral activity. Imatinib has antitumor activity for the tre... | |||
T34603 | L-Selenocystine | L-Selenocystine | Others |
L-Selenocystine (L-Selenocystine) can be used as a building block in biologically active selenol compounds. | |||
T3407 | Rapastinel | GLYX-13,Thr-Pro-Pro-Thr-NH2,TPPT-amide | NMDAR , iGluR |
Rapastinel (TPPT-amide) (GLYX-13) is an N-methyl-D-aspartate receptor (NMDAR) modulator. | |||
T34973 | Tyrphostin 8 | 4-Hydroxybenzylidenemalononitrile | EGFR , GTPase |
Tyrphostin 8(4-Hydroxybenzylidenemalononitrile) is a potent GTPase inhibitor that inhibits EGFR kinase with an IC50 of 560 μM.Tyrphostin 8 inhibits protein serine/threonine calmodulin phosphatases (IC50=21 μM), enhances ... | |||
T16778 | Rocastine | AHR-11325 | Histamine Receptor |
Rocastine (AHR-11325) is a selective and potent non-sedating H1 receptor antagonist. | |||
T11035 | DiABZI STING agonist-1 (Tautomerism) | diABZI STING agonist (Compound 3) | STING |
diABZI STING agonist-1 (Tautomerism) (diABZI STING agonist (Compound 3)) is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively. | |||
T0095 | Bendamustine hydrochloride | SDX-105,SDX-105 (Cytostasane) HCl,Bendamustine HCl,EP-3101 | Apoptosis , DNA Alkylator/Crosslinker , DNA/RNA Synthesis |
Bendamustine hydrochloride (EP-3101) (IC50 of 50 μM) is an alkylating agent associated with DNA damage. | |||
T5819 | Rapastinel Trifluoroacetate | Thr-Pro-Pro-Thr-NH2 Trifluoroacetate,GLYX-13 Trifluoroacetate | NMDAR , iGluR |
Rapastinel Trifluoroacetate (GLYX-13 Trifluoroacetate) is an NMDA receptor modulator with glycine-site partial agonist properties. | |||
T3091 | Carmustine | bis-chloroethylnitrosourea,Nitrumon,Gliadel,BCNU,BiCNU,Carmubris | DNA Alkylator/Crosslinker , DNA Alkylation |
Carmustine (bis-chloroethylnitrosourea) is a cell-cycle phase nonspecific alkylating antineoplastic agent. | |||
T0598 | Iminostilbene | Dibenzazepine | Others |
Iminostilbene (Dibenzazepine) (Dibenzazepine) is a chemical precursor of carbamazepine which is used primarily in the treatment of epilepsy and neuropathic pain. | |||
T0780 | Pyridostigmine bromide | Mestinon | AChE |
Pyridostigmine bromide (Mestinon) is a cholinesterase inhibitor with a slightly longer duration of action than NEOSTIGMINE. It is used in the treatment of myasthenia gravis and to reverse the actions of muscle relaxants. | |||
T0118 | Mizolastine | SL 850324 | Histamine Receptor |
Mizolastine (SL 850324) (IC50= 47 nM) is a histamine H1-receptor antagonist.It is used in the treatment of allergic reactions such as hay fever (seasonal allergic rhinitis), hives. | |||
T1624 | Neostigmine bromide | Neoserine bromide,Eustigmin bromide | AChE |
Neostigmine bromide is a cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not ... | |||
T8380 | Bendamustine | SDX105 | Apoptosis , Others , DNA Alkylator/Crosslinker |
Bendamustine (SDX105) for the treatment of Non-Hodgkin Lymphomas and Chronic Lymphocytic Leukemia | |||
T8987 | Epiblastin A | Casein Kinase | |
Epiblastin A is an inhibitor of Casein Kinase 1 (CK1). Epiblastin A engages CK1 isoenzymes in cell lysate and induces efficient conversion of epiblast stem cells (EpiSCs) into embryonic stem cells (cESCs). | |||
T15183 | Dynarrestin | Hedgehog/Smoothened | |
Dynarrestin is an inhibitor of cytoplasmic dyneins 1 and 2. Dynarrestin suppresses hedgehog (Hh)-dependent proliferation of neuronal precursors and tumor cells. It inhibits dynein 1-driven microtubule gliding in vitro pl... | |||
T0246L | Betahistine mesylate | Extovyl,Melopat,Meginalisk | Histamine Receptor |
Betahistine mesylate (Extovyl) is a histamine analog and H1 receptor agonist that serves as a vasodilator. It is used in MENIERE DISEASE and in vascular headaches but may exacerbate bronchial asthma and peptic ulcers. | |||
T0229 | Rivastigmine | SDZ-ENA 713,S-Rivastigmine,Exelon | AChE |
Rivastigmine (Exelon) is a Cholinesterase Inhibitor, used for therapy of Alzheimer disease. | |||
T7893 | Bepotastine | Bepotastine free base | Others , Histamine Receptor |
Bepotastine (Bepotastine free base) free base is a histamine 1 (H1) receptor antagonis. | |||
T12607 | Quinupristin | Antibacterial , Antibiotic | |
Quinupristin is a member of the macrolide-lincosamide-streptogramin class of antibiotics. Quinupristin blocks peptide bond synthesis to prevent the extension of polypeptide chains and promote the detachment of incomplete... | |||
T0723 | Cloperastine hydrochloride | HT-11 hydrochloride | Potassium Channel , 5-HT Receptor |
Cloperastine hydrochloride (HT-11 hydrochloride) is a type of flavonoid. | |||
T2335 | Ebastine | Ebastel,LAS-W 090,Ebastin,Kestine,RP64305 | Histamine Receptor |
Ebastine (Kestine) (trade names Evastin, Kestine, Ebastel, Aleva) is a non-sedating H1 antihistamine. It does not penetrate the blood-brain barrier and thus allows an effective block of the H1 receptor in peripheral tiss... | |||
T2479 | Tyrphostin A9 | Malonoben,Tyrphostin 9,SF 6847,AG 17,RG-50872 | EGFR , VEGFR , Influenza Virus , PDGFR |
Tyrphostin A9 (SF 6847) is an Agricultural acaricide, now superseded. Tyrphostin A9 is firstly designed as an EGFR inhibitor | |||
T5516 | DiABZI STING agonist-1 trihydrochloride | STING | |
diABZI STING agonist-1 (trihydrochloride) is stimulator of interferon genes (STING) receptor agonist. | |||
T67707 | Tyrphostin AG 538 | AG 538 | IGF-1R |
Tyrphostin AG 538 is a chalcone compound, an IGF-1 receptor kinase inhibitor (IC₅0 : for 400 nM) that is potent, cell-permeable, reversible, and competitive. | |||
T0147 | Clemastine fumarate | HS-592 (fumarate),Meclastine fumarate,Meclastine (fumarate) | Autophagy , Histamine Receptor |
Clemastine fumarate (Meclastine (fumarate)) is a synthetic ethanolamine with anticholinergic, sedative, and histamine H1 antagonistic properties. | |||
T13619 | Cloperastine fendizoate | Hustazol | EGFR |
Cloperastine fendizoate (Hustazol) inhibits the hERG K+ currents in a concentration-dependent manner (IC50: 27 nM). | |||
TP1370L | Crosstide TFA(171783-05-4 free base) | Others | |
Crosstide is a peptide analog of glycogen synthase kinase α/β fusion protein sequence which is a substrate for Akt. | |||
T27828 | Licostinel | CGP 63446,ACEA1021,ACEA 1021,ACEA-1021,CGP-63446 | GluR |
Licostinel (CGP 63446) is a glutamate receptor antagonist. Licostinel protects against permanent focal cerebral ischemia. | |||
T72482 | Dazostinag disodium | STING | |
Dazostinag disodium (TAK-676) is a novel stimulator of interferon genes (STING) agonist and immune system modulator with antitumor activity that activates dendritic cells, natural killer cells, and T cells. | |||
T74809 | STING agonist-30 | STING , Antifection | |
STING agonist-30 is a potent STING agonist that triggers STING-dependent immune activation.STING agonist-30 shows broad-spectrum inhibitory effects against a variety of viruses including HSV (Herpes Simplex Virus), rotav... | |||
T7537 | Norgestimate | Progesterone Receptor | |
Norgestimate is an acetylated progestinused in combination with ethinyl estradiol as an oral contraceptive. | |||
T0211 | Azelastine | Azelastina,Astelin,Azelastinum | SARS-CoV , Histamine Receptor |
T68150 | Talastine | Histamine Receptor | |
Talastine is an antihistamine compound that can induce an allergic rash. | |||
T4508 | Glycyl-L-Histidyl-L-Lysine | Others | |
Glycyl-L-histidyl-L-lysine is a liver cell growth factor and an asynthetic hepatotrophic agent that stimulates hepatic erythropoietic factor production. | |||
T67981 | Copper histidine | ||
Copper histidine inhibited Ctr1-mediated cellular uptake of oxaliplatin in vitro without altering oxaliplatin accumulation of platinum or neurotoxicity in DRG tissues in vivo. Copper histidine is administered orally for ... | |||
T6381 | Amifostine trihydrate | Ethyol trihydrate,WR2721,Amifostine | Others , HIF/HIF Prolyl-Hydroxylase |
Amifostine trihydrate (WR2721) is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin. | |||
T6711 | Tyrphostin AG1296 | Tyrphostin AG 1296,AG 1296 | Apoptosis , FGFR , FLT , PDGFR , c-Kit |
Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR. | |||
T4182 | Lavendustin B | Tyrosinase , transporter , HIV Protease | |
Lavendustin B is a Tyrosine Kinase Inhibitor and an inhibitor of HIV-1 integrase (IN) interaction with its cognate cellular cofactor, lens epithelium-derived growth factor (LEDGF/p75). | |||
T9029 | STING-IN-3 | C-171 | STING |
STING-IN-3 (C-171) is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1. | |||
T8328 | STING agonist-1 | G10 | Virus Protease , STING |
STING agonist-1 (G10) is a human-specific STING agonist,elicits antiviral activity against emerging Alphaviruses. | |||
T25146 | Bestim | Others | |
Bestim is an immunomodulatory dipeptide that is synthetic. | |||
T28663 | Sarmustine | NSC-364432,SarCNU,Sarcosinamide,NSC 364432,NSC364432 | |
Sarmustine (SarCNU) is an alkylating agent with anticancer activity that inhibits the growth of prostate cancer cells via p53-dependent and p53-independent pathways.Sarmustine mediates the selection of P140K methylguanin... | |||
T21622 | Tyrphostin A25 | AG-82,Tyrphostin AG 82,RG-50875 | EGFR , GPR |
Tyrphostin A25 (Tyrphostin AG 82) is a specific EGFR tyrosine kinase inhibitor and GPR35 agonist with an IC50 value of 0.94 μM for GPR35 and an EC50 value of 5.3 μM for GPR35. | |||
T4551 | Acrivastine | Acrivastin,BW825C,Semprex | Histamine Receptor |
Acrivastine (Acrivastin) is a short-acting histamine 1 receptor antagonist. | |||
T73746 | DiABZI STING agonist-1 | ||
DiABZI STING Agonist-1 is a selective receptor agonist for the stimulator of interferon genes (STING), demonstrating efficacy with EC50 values of 130 nM and 186 nM in human and mouse models, respectively. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T4852 | Trimyristin | Trimyristoylglycerol,Tritetradecanoin,Glyceryl trimyristate,1,2,3-Tritetradecanoylglycerol | Phosphatase , Endogenous Metabolite , AChE |
Trimyristin (Tritetradecanoin) is primarily located in the membrane (predicted from logP) and adiposome. glyceryl trimyristate exists in all eukaryotes, ranging from yeast to humans. In humans, glyceryl trimyristate is i... | |||
T12540 | Pristinamycin IA | Mikamycin IA,Mikamycin B | Others , Antibiotic , P-gp |
Pristinamycin IA (Mikamycin B) is a substrate for the P-glycoprotein and a cyclo-peptidic macrolactone antibiotic. | |||
TN2159 | Robustine | PDE | |
Robustine is a natural product, exhibits inhibitory potency against human phosphodiesterase 5 (hPDE5A) in vitro. | |||
T4899 | L-Histidinol dihydrochloride | Endogenous Metabolite | |
L-Histidinol dihydrochloride is a precursor of histamine and a reversible inhibitor of protein synthesis. | |||
T3501 | Colistimethate Sodium | Colistin-1,3,5,9-tetramethanesulfonic A acid | Others |
Colistin-1,3,5,9-tetramethanesulfonic A acid is used for the treatment of serious infections due to selected aerobic Gram-negative pathogens in patients with limited treatment options. | |||
TQ0152 | Dalfopristin | RP54476 | Antibacterial , Antibiotic |
Dalfopristin (RP54476) is a semi-synthetic streptogramin antibiotic. Quinupristin/Dalfopristin (Q/D) is used for the treatment of multi-drug resistant Enterococcus faecium infections. | |||
T4183 | Lavendustin A | RG-14355,NSC 678027 | EGFR , Tyrosinase |
lavendustin A (RG-14355) is a potent, cell-permeable inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase. | |||
T2866 | Echinocystic acid | Apoptosis , Antioxidant , Reactive Oxygen Species | |
Echinocystic acid (EA), a natural triterpone enriched in various herbs, shows a range of pharmacological activities including anti-inflammatory and antioxidant effects. | |||
T4S1050 | Pristimerin | Celastrol methyl ester | NF-κB , Antibacterial |
1. Pristimerin (Celastrol methyl ester) has anticancer activity , treatment with Pristimerin may be a potential strategy for the suppression of hypoxia-induced metastasis through the reversal of hypoxia-induced stem cell... | |||
TN1019 | Beta-mangostin | β-Mangostin | Apoptosis , Antibacterial , Parasite |
Beta-mangostin (β-Mangostin) is a xanthone compound with antibacterial and antimalarial activities. Beta-mangostin present in Cratoxylum arborescens and exhibits antimycobacterial activity against Mycobacterium tuberculo... | |||
T4859 | 1-Monomyristin | rac-Glycerol 1-myristate,Glyceryl myristate,Monomyristin,2,3-Dihydroxypropyl tetradecanoate | Others , FAAH , Endogenous Metabolite , Antibacterial , Autophagy , Antifungal |
1-Monomyristin (2,3-Dihydroxypropyl tetradecanoate) , a 1-monoglyceride of myristic acid, has antibacterial activity against several Gram-positive bacterial strains. 1-Myristoyl-rac-glycerol is used in colloidal chemistr... | |||
T2967 | Stigmasterol | Stigmasterin,beta-Stigmasterol | MMP , Endogenous Metabolite |
Stigmasterol (Stigmasterin) is found in the fats and oils of soybean, calabar bean and rape seed, as well as several other vegetables, legumes, nuts, seeds, and unpasteurized milk. Stigmasterol has been focused on the ch... | |||
T35673 | Stictic Acid | Scopularic acid | Others |
Stictic Acid (Scopularic acid) is isolated from a Sumatran lichen Stereocaulon montagneanum and inhibits the growth of HT-29 human colon adenocarcinoma cells with an IC50 of 29.29 μg/ml. | |||
T4956 | Tetrahydroxystilbene-2-O-β-D-glucoside | tetrahydroxyl diphenylethylene-2-o-gluco,EH-201 | Others |
Tetrahydroxystilbene-2-O-β-D-glucoside (EH-201) is a low MW inducer of erythropoietin. Tetrahydroxystilbene-2-O-β-D-glucoside induces expression of erythropoietin, PPAR-γ coactivator 1α (PGC-1α) and haemoglobin in astroc... | |||
T3755 | Pinostilbene | Others | |
Pinostilbene obviously attenuates the phosphorylation of c-Jun and JNK triggered by 6-OHDA. | |||
T12564 | Prudomestin | 3,5,7-Trihydroxy-4',8-dimethoxyflavone | Xanthine Oxidase |
Prudomestin (3,5,7-Trihydroxy-4',8-dimethoxyflavone) is a natural product isolated from the heartwood of Prunus domestica, with xanthine oxidase (XO) inhibitory activity with IC50 of 6 µM. | |||
T2888 | Pterostilbene | Autophagy | |
Pterostilbene is extracted from Pterocarpus indicus. | |||
T1668 | Vinblastine sulfate | NSC49842,Vincaleukoblastine sulfate salt | Microtubule Associated , AChR , Autophagy |
Vinblastine sulfate (Vincaleukoblastine sulfate salt) can inhibit the formation of microtubule, it also inhibits nAChR(IC50=8.9 uM). | |||
TN2546 | 1-Isomangostin | NF-κB | |
1-Isomangostin has cytotoxic and anticomplementary activities. | |||
T36818 | Questiomycin A | GPR , Antibacterial | |
Questiomycin A is an antibiotic produced in crème fraiche with antibacterial and anticancer activities. Questiomycin A suppresses expression of GRP78, a cell-protective ER chaperone protein. | |||
TQ0160 | Hydrastine | (-)-β-Hydrastine,(1R,9S)-β-Hydrastine | Others |
Hydrastine ((-)-β-Hydrastine) is a natural alkaloid that is present in Hydrastis Canadensis. | |||
T2S2382 | 3'-Hydroxypterostilbene | 3'-HPT | Apoptosis , Autophagy |
3'-Hydroxypterostilbene (3'-HPT), a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells with IC50s of 9.0, 40.2, and 70.9 μM for COLO 205, HCT-116, and HT-29 cells, respectively, b... | |||
TN2282 | Trans-Stilbene | 1,2-Diphenylethylene (trans),(E)-Stilbene | Others |
trans-Stilbene (1,2-Diphenylethylene (trans)) is a natural product used in the manufacture of dye lasers, optical brighteners, and non-steroidal synthetic estrogens. | |||
T1245 | Colistin sulfate | Colistin sulfate (1066-17-7 free base),Polymixin E Sulfate,Polymyxin E Sulfate | Cell wall , Antibacterial , Antibiotic , Autophagy |
Colistin sulfate (Colistin sulfate (1066-17-7 free base)) is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2. | |||
T4877 | L-Homocystine | Endogenous Metabolite | |
Homocystine is the double-bonded form of homocysteine, but it occurs only transiently before being converted to the harmless cystathionine via a vitamin B6-dependent enzyme. Increasing evidence supports a role for an ele... | |||
T2S1635 | 3-Isomangostin | MTH1 | |
3-Isomangostin is a potent human aldose reductase inhibitor with an IC50 of 3.48 uM; it is also an acetylcholinesterase selective inhibitor. 3-Isomangostin has free radical scavenging activity; it shows antiplasmodial ac... | |||
TQ0191 | Dihydromethysticin | (+)-Dihydromethysticin | P450 |
Dihydromethysticin ((+)-Dihydromethysticin) is a kavalactone found in Piper methysticum. It has marked activity on the induction of CYP3A23. | |||
T6S1373 | Casticin | Quercetagetin 3,6,7,4'-Tetramethyl Ether,Vitexicarpin | STAT |
1. Casticin (Vitexicarpin) can significantly reduce vascular inflammation, through inhibition of ROS-NF-κB pathway in vascular endothelial cells. 2. Casticin may become a potential leading drug in the therapy of prostate... | |||
T0130 | Physostigmine Salicylate | AChR , AChE | |
Physostigmine, a parasympathomimetic alkaloid, is a reversible cholinesterase inhibitor. It extracts from the Calabar bean. | |||
TN1772 | Isoastilbin | Anti-infection , Tyrosinase , Antibacterial | |
Isoastilbin is a dihydroflavonol glycoside compound in Rhizoma Smilacis glabrae and Astragalus membranaceus. Isoastilbin inhibits glucosyltransferase (GTase) with an IC50 value of 54.3 μg/mL, Isoastilbin has anti-acne an... | |||
T3879 | Silychristin | Silicristin | Lipoxygenase |
Silychristin (Silicristin) is a plant growth regulator. Silychristin is an anti-hepatotoxic agent. Silychristin is the inhibitor of horseradish peroxidases and lipoxygenase. | |||
T4S1637 | Gamma-Mangostin | Normangostin | Others , 5-HT Receptor |
1. gamma-Mangostin (Normangostin) as a preventive agent of the metabolic syndrome. 2. Gamma-Mangostin has free radical scavenging activity, and antiproliferative and apoptotic activity in HepG2 cells. 3. Gamma-Mangostin ... | |||
T1270 | Vincristine sulfate | Leurocristine,22-Oxovincaleukoblastine sulfate,Leurocristine sulfate | Apoptosis , Microtubule Associated |
Vincristine sulfate (Leurocristine sulfate) binds irreversibly to microtubules and spindle proteins in S phase and interferes the formation of the mitotic spindle. | |||
T3S0209 | Vincristine | ERK , p38 MAPK , NF-κB , Akt , JNK , mTOR | |
Vincristine-induced nociceptive painful sensation, may be due to its potential of antioxidative, neuroprotective and calcium channel inhibitory action.Vincristine can treat MM, ERK1/2, Akt, and NF-κB inhibitors are pote... | |||
T4826 | L-Histidine monohydrochloride monohydrat | Others , Endogenous Metabolite | |
Histidine (abbreviated as His or H) is an alpha-amino acid. The L-isomer is one of the 22 proteinogenic amino acids, i.e., the building blocks of proteins. It is classified as a charged, polar because of the hydrophilic ... | |||
T21518 | Colistin methanesulfonate sodium salt | Colistin Methanesulfonate (sodium salt) | Cell wall , Antibacterial |
Colistin methanesulfonate sodium salt (Colistimethate Sodium) is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2. | |||
T2882 | Genistin | Genistoside,Genistein glucoside,Genistein 7-glucoside,Genistine,Genistein 7-O-β-D-glucopyranoside | Apoptosis , Estrogen Receptor/ERR , Others |
Genistin (Genistoside) is the major isoflavonoid of soybeans and soy products.It has been reported to possess various therapeutic effects, including anti-inflammatory and anticancer activities | |||
T16338 | Norgestimate metabolite Norelgestromin | 17-Deacetyl norgestimate,17-Deacylnorgestimate | Drug Metabolite |
Norgestimate metabolite Norelgestromin (17-Deacylnorgestimate) is one of the active metabolites of norgestimate.It is a steroidal progestin used in contraceptive patches, where it is combined with the estrogen ethinyl es... | |||
T60789 | L-Cystine dihydrochloride | Nrf2 | |
L-Cystine dihydrochloride is an Nrf2 inducer with whitening and anti-dark spot effects.L-Cystine dihydrochloride has cytoprotective effects in cells, and is often added to various fungal cultures as a carbon source. | |||
T2794 | Astilbin | Neoastilbin,Taxifolin 3-O-rhamnoside,Isoastilbin,Taxifolin 3-rhamnoside,Neoisoastilbin | TNF , NF-κB , Nrf2 |
Astilbin (Neoastilbin) is actions Flavonoid phytochemical found in St. John′s wort and Traditional Chinese Medicine herbal preparations. | |||
T2A2532 | L-Histidine | Glyoxaline-5-alanine,L-(-)-Histidine,histidine,L-Hisidine | Mitochondrial Metabolism , Endogenous Metabolite |
L-Histidine (L-(-)-Histidine) is a semi-essential amino acid (children should obtain it from food) needed in humans for growth and tissue repair, L-Histidine is important for maintenance of myelin sheaths that protect ne... | |||
T4934 | 1-Methyl-L-histidine | 3-(1-Methylimidazol-4-yl)-L-alanine,Nτ-Methyl-L-histidine | Endogenous Metabolite |
1-Methyl-L-histidine (3-(1-Methylimidazol-4-yl)-L-alanine) is a natural but non-proteinogenic amino acid; employed as index of muscle protein breakdown. | |||
T5S1287 | Ligustilide | Apoptosis , Autophagy | |
3-Butylidene-4,5-dihydrophthalide is an effective constituent extracted from Angelica sinensis. | |||
T9113 | Myristicin | Myristicine | IL Receptor , Anti-infection , BCL , P450 , PARP , 5-HT Receptor , Caspase , GABA Receptor , NO Synthase |
Myristicin (Myristicine) is a natural product found in spices and umbelliferous plants. Myristicin has anti-cholinergic, Antibacterial, and hepatoprotective effects, it also has anti-inflammatory properties related with ... | |||
T2O2733 | L-Cystine | Cystine Acid,cystine | Antioxidant , Ferroptosis , Endogenous Metabolite |
L-Cystine (Cystine Acid) is not considered one of the 20 amino acids, L-Cystine (Cystine Acid) is a sulfur-containing derivative obtained from oxidation of cysteine amino acid thiol side chains. It functions as an antiox... | |||
T64911 | Blasticidin S HCl | Antibiotic | |
Blasticidin S HCl is a peptide-based nucleoside antibiotic (antibiotic) isolated from Streptomyces griseochromogenes that inhibits prokaryotic and eukaryotic protein synthesis by interfering with the formation of peptide... | |||
T1717 | Alpha-Mangostin | α-Mangostin,Mangostin | Apoptosis , Virus Protease , Dehydrogenase , Reactive Oxygen Species , Antibacterial , Antifungal |
alpha-Mangostin (Mangostin) is a natural xanthonoid, a type of organic compound isolated from various parts of the mangosteen tree. | |||
TN7115 | 3,5-Dimethoxystilbene | cis-Pinosylvin dimethyl ether | Others |
3,5-Dimethoxystilbene (cis-Pinosylvin dimethyl ether) is a natural product isolated from the bark of jack pine (Pinus bunksiuna). | |||
T16943 | Stigmastanol | Endogenous Metabolite | |
Stigmastanol is a phytosterol. | |||
TN2347 | Methylsticin | Methysticin | Others |
Methysticin is a kavalactone isolated from the kava roots. Methylsticin (Methysticin) exhibit osteoclast formation inhibitory activity. It inhibits activation of NF-χB in lung adenocarcinoma tissue, activates Nrf2 in neu... | |||
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カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-02441 | Alanyl-tRNA synthetase Protein, Mouse, Recombinant (His) | Mouse | Baculovirus Insect Cells |
alanyl-tRNA synthetase Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 108.3 kDa and the accession number is Q8BGQ7. | |||
TMPY-01020 | Periostin/OSF-2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Periostin/OSF-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.4 kDa and the accession number is Q15063-3. | |||
TMPY-01613 | Periostin/OSF-2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Periostin/OSF-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 89 kDa and the accession number is Q62009-2. | |||
TMPH-03615 | Ribonuclease J Protein, Synechocystis sp., Recombinant (His & SUMO) | Synechocystis | E. coli |
An RNase that has 5'-3' exonuclease and possibly endoonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. Ribonuclease J Protein, Synechocystis sp., Recombinant (His... | |||
TMPH-03721 | IbpA Protein, Yersinia pestis bv. Antiqua, Recombinant (His) | Yersinia pestis | E. coli |
Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the Ibp... | |||
TMPY-01605 | STIM1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Stromal interaction molecule 1, also known as STIM1 and GOK, is a cell membrane, a single-pass type I membrane protein and a endoplasmic reticulum membrane protein. STIM1 / GOK is ubiquitously expressed in various human ... | |||
TMPH-03652 | Ustilago maydis P6 virus (UmV6) KP6 killer toxin (His) | UmV6 | P. pastoris (Yeast) |
This protein is lethal to sensitive cells of the same or related species. The KP6 alpha subunit is known to recognize some cellular receptors before interaction of the complex with KP6 beta, precipitating cell death. Ust... | |||
TMPH-01752 | Nestin/NES Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cell... | |||
TMPH-00399 | RPS13 Protein, Ciona intestinalis, Recombinant (His & Myc) | Ciona intestinalis | E. coli |
RPS13 Protein, Ciona intestinalis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 23.9 kDa and the accession number is Q8I7D6. | |||
TMPY-02660 | Resistin Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Resistin is an adipocytokine, which has been studied for its role in insulin resistance and recently in inflammation. The RETN and CAP1 polymorphisms and gene expression may be potential biomarkers for breast cancer risk... | |||
TMPY-06689 | Fel d 1 Protein, Felis domesticus, Recombinant | Felis domesticus | E. coli |
Fel d 1 Protein, Felis domesticus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 21.6 kDa. | |||
TMPH-02636 | Elastin Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulat... | |||
TMPY-06674 | Fel d 4 Protein, Felis domesticus, Recombinant | Felis domesticus | E. coli |
Fel d 4 Protein, Felis domesticus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 32.5 kDa. | |||
TMPH-03722 | Coagulase/fibrinolysin Protein, Yersinia pestis, Recombinant (His & Myc) | Yersinia pestis | E. coli |
Seems to play an essential role in plague transmission by mediating flea blockage in a temperature-dependent fashion. Fibrinolytic activity prevails at 37 degrees Celsius whereas coagulase expression predominates at lowe... | |||
TMPK-00684 | Alkaline phosphatase (Intestinal type) /ALPI Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPJ-01206 | Sting Protein, Human, Recombinant (Sumo & His) | Human | E. coli |
Stimulator of Interferon Gene(Sting,TMEM173) belongs to the TMEM173 family. STING is 379 amino acids (aa) in length. It contains an N-terminal cytoplasmic region (aa 1-20), four transmembrane segments (aa 21-173), and a ... | |||
TMPY-06737 | Equ c 1 Protein, Domestic horse, Recombinant | Domestic horse | E. coli |
Equ c 1 Protein, Domestic horse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 21.1 kDa. | |||
TMPH-00094 | HSP21, chloroplastic Protein, Arabidopsis thaliana, Recombinant (His & Myc) | Arabidopsis thaliana | E. coli |
Chaperone protein required for seedling and chloroplast development under heat stress, probably by maintaining plastid-encoded RNA polymerase (PEP)-dependent transcription. HSP21, chloroplastic Protein, Arabidopsis thali... | |||
TMPY-06736 | Bos d 2 Protein, Bos domesticus, Recombinant | Bos domesticus | E. coli |
Bos d 2 Protein, Bos domesticus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 32.4 kDa. | |||
TMPH-00078 | Beta-amylase 1, chloroplastic Protein, Arabidopsis thaliana, Recombinant (His & Myc) | Arabidopsis thaliana | E. coli |
Beta-amylase activity. Can use p-nitrophenyl maltopentaoside (PNPG5) as substrate only in reduced form. Can play a minor role in the starch degradation and maltose metabolism in chloroplasts during the night. More active... | |||
TMPH-00016 | Ferredoxin Protein, Acetoanaerobium sticklandii, Recombinant (His & Myc) | Acetoanaerobium sticklandii | E. coli |
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | |||
TMPH-03653 | RNU2 Protein, Ustilago sphaerogena, Recombinant (B2M & His) | Ustilago sphaerogena | E. coli |
N/A. RNU2 Protein, Ustilago sphaerogena, Recombinant (B2M & His) is expressed in E. coli expression system with N-6xHis-B2M tag. The predicted molecular weight is 26.4 kDa and the accession number is P00654. | |||
TMPH-01872 | Plastin-2 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Actin-binding protein. Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and CD69. Plastin-2 Protein, Human, Recom... | |||
TMPH-01887 | Polycystin-1 Protein, Human, Recombinant (His) | Human | E. coli |
Polycystin-1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 69.3 kDa and the accession number is P98161. | |||
TMPY-03987 | T Plastin/PLS3 Protein, Human, Recombinant (His) | Human | E. coli |
PLS3, also known as plastin 3, belongs to the plastin family. Members of this family are actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. There ... | |||
TMPH-02448 | Mal d 1 Protein, Malus domestica, Recombinant (His) | Apple | P. pastoris (Yeast) |
Mal d 1 Protein, Malus domestica, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 19.5 kDa and the accession number is P43211. | |||
TMPH-03725 | LcrV Protein, Yersinia pestis, Recombinant (His & Myc & SUMO) | Yersinia pestis | E. coli |
Possibly involved in calcium regulation of YOP expression, which includes the export process. | |||
TMPH-01871 | Plastin-2 Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Actin-binding protein. Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and CD69. Plastin-2 Protein, Human, Recom... | |||
TMPH-02449 | Mal d 1 Protein, Malus domestica, Recombinant (His & SUMO) | Apple | E. coli |
Mal d 1 Protein, Malus domestica, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 33.5 kDa and the accession number is P43211. | |||
TMPK-00796 | Alkaline phosphatase (Intestinal type) /ALPI Protein, Human, Recombinant (His & Flag) | Human | HEK293 Cells |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPH-02928 | Testican-2 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
May participate in diverse steps of neurogenesis. Binds calcium. Testican-2 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is... | |||
TMPH-03724 | F1 capsule antigen Protein, Yersinia pestis, Recombinant (His) | Yersinia pestis | P. pastoris (Yeast) |
F1 capsule antigen Protein, Yersinia pestis, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 17.6 kDa and the accession number is P26948. | |||
TMPH-00079 | Beta-amylase 3, chloroplastic Protein, Arabidopsis thaliana, Recombinant (His) | Arabidopsis thaliana | E. coli |
Beta-amylase activity. No alpha-amylase activity. Involved in cold resistance. Mediates the accumulation of maltose upon freezing stress, thus contributing to the protection of the photosynthetic electron transport chain... | |||
TMPH-03723 | F1 capsule antigen Protein, Yersinia pestis, Recombinant (E. coli, His) | Yersinia pestis | E. coli |
F1 capsule antigen Protein, Yersinia pestis, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 19.6 kDa and the accession number is P26948. | |||
TMPH-02450 | MALD3 Protein, Malus domestica, Recombinant (His & SUMO) | Apple | E. coli |
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory... | |||
TMPH-00298 | Resistin Protein, Bovine, Recombinant (His) | Bovine | E. coli |
Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. Potentially links obesity to diabetes. Resistin Protein, Bovine, Recombinant (His) is expressed in E. coli expression system ... | |||
TMPJ-00014 | Resistin Protein, Human, Recombinant (His) | Human | E. coli |
Resistin known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) that seems to suppress insulin ability to stimulate glucose uptake into ... | |||
TMPK-00973 | Periostin/OSF-2 Protein, Human, Recombinant (aa 22-836, His) | Human | HEK293 Cells |
Periostin/OSF-2 Protein, Human, Recombinant (aa 22-836, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 92.1 kDa and the accession number is Q15063. | |||
TMPJ-01377 | Testin Protein, Human, Recombinant (His) | Human | E. coli |
Testin belongs to the prickle/espinas/testin family. Testin contains three LIM zinc-binding domains and one PET domain, TES as a scaffold protein that may have a role in cell adhesion, cell spreading and in the reorganiz... | |||
TMPK-01032 | Periostin/OSF-2 Protein, Mouse, Recombinant (aa 24-811, His) | Mouse | HEK293 Cells |
Periostin/OSF-2 Protein, Mouse, Recombinant (aa 24-811, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 88.7 kDa and the accession number is Q62009-1. | |||
TMPJ-00579 | Ameloblastin Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Ameloblastin (AMBN) is a member of the Ameloblastin family. AMBN is a secreted protein and is specially expressed in ameloblast, localizing to the Tomes processes of secretory ameloblasts and in the sheath space between ... |