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カタログ番号 | 製品名 | 別名 | ターゲット |
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TP1309 | Gastric mucin | Antibacterial , Antibiotic | |
Gastric mucin is a large glycoprotein which is thought to play a major role in the protection of the gastrointestinal tract from acid, proteases, pathogenic microorganisms, and mechanical trauma. | |||
T78543 | Acetyl Gastric Inhibitory Peptide (human) TFA | Human N-acetyl GIP TFA | |
Acetyl Gastric Inhibitory Peptide (human) TFA, a fatty acid-derivatized analog of the glucose-dependent insulinotropic polypeptide, exhibits enhanced antihyperglycemic and insulinotropic properties. It is utilized in the... | |||
T76309 | Gastric Inhibitory Peptide, porcine | ||
Gastric Inhibitory Peptide (porcine), also known as a glucose-dependent insulinotropic polypeptide, is a 42-amino acid intestinal hormone that influences fat and glucose metabolism [1]. | |||
T76307 | [Tyr0] Gastric Inhibitory Peptide (23-42), human | ||
[Tyr0] Gastric Inhibitory Peptide (23-42), human, functions as a glucose-dependent insulinotropic polypeptide (GIP) and exhibits dual activity: it modestly inhibits gastric acid secretion while simultaneously enhancing i... | |||
T76310 | Acetyl Gastric Inhibitory Peptide (human) | ||
Acetyl Gastric Inhibitory Peptide (human), a fatty acid-derivatized analog of glucose-dependent insulinotropic polypeptide, exhibits enhanced antihyperglycemic and insulinotropic characteristics. This compound is utilize... | |||
T83710 | Gastric Inhibitory Peptide (22-51) (human) TFA | GIP (22-51),Glucose-dependent Insulinotropic Peptide (22-51) | |
Gastric inhibitory peptide (GIP) (22-51), a pro-atherogenic peptide comprised of 30 amino acids from the residues 22-51 of its precursor protein proGIP, is present in human plasma. It activates the degradation of IκB-α a... | |||
T76308 | Gastric Inhibitory Polypeptide (1-30), porcine | ||
Gastric Inhibitory Polypeptide (1-30), porcine, deficient in the 12 C-terminal amino acids of the natural gastric inhibitory polypeptide (GIP), demonstrates biological activity through the enhancement of insulin and soma... | |||
T82332 | Gastric Inhibitory Polypeptide (6-30) amide (human) | ||
Gastric Inhibitory Polypeptide (6-30) amide (human) is an incretin hormone utilized in the research of diabetes [1]. | |||
T83694 | Gastric Inhibitory Peptide (1-42) (porcine) TFA | GIP (1-42),Glucose-dependent Insulinotropic Polypeptide (1-42) | |
Gastric inhibitory peptide (GIP) (1-42), an endogenous incretin hormone comprising 42 amino acids, promotes insulin secretion. Expressed in the intestinal neuroendocrine K cells and submandibular gland, it enters circula... | |||
T83696 | Gastric Inhibitory Peptide 1 (3-42) (human) TFA | Glucose-dependent Insulinotropic Polypeptide 3-42,GIP-1 (3-42) | |
Gastric inhibitory peptide 1 (GIP-1) (3-42), a fragment of the incretin hormone GIP and antagonist to the GIP receptor, is generated through the action of serum dipeptidyl peptidase 4 (DDP-4). When administered at 25 nmo... | |||
T37589 | GIP (3-42), human | Gastric Inhibitory Polypeptide (3-42) (human) | IGF-1R |
GIP (3-42), human (Gastric Inhibitory Polypeptide (3-42) (human)) is a peptide that acts as a glucose-dependent proinsulinotropic polypeptide (GIP) receptor antagonist and regulates insulin secretion and the metabolic ef... | |||
T17030 | Tegoprazan | ATPase , Proton pump | |
Tegoprazan is a potassium-competitive acid blocker and is a potent, oral active, and highly selective inhibitor of gastric H+/K+-ATPase. That could control gastric acid secretion and motility (IC50: ranging from 0.29-0.5... | |||
T4579 | Pentagastrin | ICI-50123 | Others , cholecystokinin |
Pentagastrin (ICI-50123) is a synthetic polypeptide that has effects like gastrin when given parenterally, which can cause the secretion and synthesis of salivary proteins. | |||
T38612 | Linaprazan glurate | Others | |
Linaprazan glurate inhibits exogenously or endogenously stimulated gastric acid secretion. Linaprazan glurate can be used in studies about gastrointestinal inflammatory diseases and peptic ulcer diseases. | |||
T4981 | Anisotropine Methylbromide | Prostaglandin Receptor , AChR | |
Anisotropine Methylbromide is an anticholinergic agent and has been used for relief of gastrointestinal spasm and for the suppression of gastric acid secretion. | |||
T15500 | HPi1 | Others , Antibacterial | |
HPi1 is a selective and orally active antimicrobial against Helicobacter pylori (IC50: 0.24 μM and a MIC of 0.08-0.16 μg/mL). HPi1 is inactive against other Xaliproden, including the gut commensals, Lactobacillus reuteri... | |||
T9929 | Ramucirumab | VEGFR | |
Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors. | |||
T22724 | Dimaprit dihydrochloride | NOS , NO Synthase , Histamine Receptor | |
Dimaprit dihydrochloride is a selective histamine H2 receptor agonist. Dimaprit dihydrochloride also inhibits nNOS with an IC50 of 49 μM. It can stimulate gastric acid secretion. | |||
T6710 | Troxipide | Aplace | Others |
Troxipide (Aplace), a new-type systemic non-antisecretory gastric cytoprotective agent, which is mucus-secreting, anti-ulcer, and anti-inflammatory properties irrespective of pH of stomach or duodenum. | |||
T1787 | Levobupivacaine | Sodium Channel | |
Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by AstraZ... | |||
T2319 | Acotiamide monohydrochloride trihydrate | Acotiamide hydrochloride,YM-443 HCl,Z-338 HCl | AChE |
Acotiamide monohydrochloride trihydrate (Z-338 HCl) is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. Although the exact mechanism by which acotiamid... | |||
T2676 | PF-04217903 | c-Met/HGFR | |
MET Tyrosine Kinase Inhibitor PF-04217903 is an orally bioavailabe, small-molecule tyrosine kinase inhibitor with potential antineoplastic activity. | |||
T6700 | Tenatoprazole | TU-199 | Proton pump |
Tenatoprazole (TU-199), a prodrug of the proton pump inhibitor (PPI) class, can inhibit proton transport (IC50: 3.2 μM). | |||
T37588 | GIP (1-30) amide, porcine | ||
This GIP fragment has potent insulinotropic activity in the isolated, perfused rat pancreas but greatly reduced somatostatinotropic activity in the isolated perfused rat stomach. The site responsible for insulinotropic a... | |||
T22368 | Metyrosine | α-Methyltyrosine | COX |
Metyrosine (α-Methyltyrosine) is an antihypertensive drug and could be used as a tyrosine hydroxylase inhibitor.Metyrosine significantly inhibits high COX-2 activity. Metyrosine is a very effective agent for blood pressu... | |||
T0865 | Ranitidine Hydrochloride | AH19065 | P450 , Antibacterial , Histamine Receptor |
Ranitidine Hydrochloride (AH19065) is a member of the class of histamine H2-receptor antagonists with antacid activity. Ranitidine is a competitive and reversible inhibitor of the action of histamine, released by enteroc... | |||
T1052 | Proglumide | cholecystokinin | |
Proglumide (Binoside) is a cholecystokinin antagonist, which blocks both the CCKA and CCKB subtypes. Proglumide is a drug that exerts an inhibitory effect on gastric secretion and reduces gastrointestinal motility. It is... | |||
T8599 | Betazole dihydrochloride | Betazole hydrochloride | Histamine Receptor |
Betazole dihydrochloride (Betazole hydrochloride) is an agonist of H2 receptor. | |||
T0081 | Lafutidine | FRG-8813 | 5-HT Receptor , Histamine Receptor |
Lafutidine (FRG-8813) is a newly developed histamine H(2)-receptor antagonist, which can inhibit gastric acid secretion. | |||
T1756L | Ilaprazole | IY81149,IY 81149,IY-81149 | Proton pump , TOPK |
Ilaprazole (IY-81149) is a proton pump inhibitor used in the treatment of dyspepsia gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer. Studies also showed that Ilaprazole significantly prevented the developm... | |||
T3610 | Ranitidine | HSDB 3925,Ranitidin | P450 , Antibacterial , Histamine Receptor |
Ranitidine (HSDB 3925) is a non-imidazole blocker of those histamine receptors that mediate gastric secretion (H2 receptors). It is used to treat gastrointestinal ulcers. | |||
T0686 | Orlistat | Ro-18-0647,Tetrahydrolipstatin | Apoptosis , Others , Fatty Acid Synthase |
Orlistat (Tetrahydrolipstatin) is an Intestinal Lipase Inhibitor. The mechanism of action of orlistat is as a Lipase Inhibitor. | |||
T1562 | Rebamipide | Proamipide,OPC12759 | Free radical scavengers , COX , Prostaglandin Receptor |
Rebamipide (OPC12759) is a quinolinone derivative with anti-ulcer and anti-inflammatory activities. Rebamipide induces cyclooxygenase 2 (COX2) synthesis which results in an increase in endogenous prostaglandin synthesis ... | |||
T1756 | Ilaprazole sodium | IY-81149 sodium | Proton pump , TOPK |
Ilaprazole sodium (IY-81149 sodium) , a substituted benzimidazole prodrug, is a selective and irreversible proton pump inhibitor. A weak base, Ilaprazole accumulates in the acidic environment of the secretory canaliculus... | |||
T14975 | CJ-42794 | CJ-042794 | Others |
CJ-42794 (CJ-042794) is a selective antagonist of prostaglandin E receptor subtype 4 (EP4). It inhibits [3H]-PGE2 binding to the human EP4 receptor (a mean pKi: 8.5). CJ-42794 is a binding affinity that was at least 200-... | |||
T11139 | (E/Z)-BCI | NSC 150117 | Apoptosis , Phosphatase |
(E/Z)-BCI (NSC-150117), a dual-specificity phosphatase 6 (DUSP6) inhibitor with anti-inflammatory properties, reduces LPS-induced inflammatory mediators and ROS production in macrophage cells by activating the Nrf2 signa... | |||
T1394 | Ibuprofen | Brufen,(±)-Ibuprofe,Motrin,Advil | COX |
Ibuprofen (Advil) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resu... | |||
T0674 | Lansoprazole | A-65006,AG-1749 | Proton pump , Phospholipase , Antibacterial |
Lansoprazole (A-65006) is a 2, 2, 2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is fo... | |||
T11826 | LCH-7749944 | GNF-PF-2356 | Apoptosis , PAK |
LCH-7749944 (GNF-PF-2356) effectively suppresses the proliferation of human gastric cancer cells through downregulation of PAK4/c-Src/EGFR/cyclin D1 pathway and induces apoptosis. LCH-7749944 is a potent PAK4 inhibitor w... | |||
T2325 | Neratinib | HKI-272 | EGFR , HER |
Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively. | |||
T6540 | Ibuprofen Lysine | Neoprofen | COX |
Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug. | |||
T8505 | SC-236 | Sc 236 | Apoptosis , COX , PPAR |
SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively). | |||
T1552 | Itopride hydrochloride | HSR803,Ganaton | Dopamine Receptor , AChE |
Itopride hydrochloride (Ganaton) is an AChE and D2DR inhibitor. | |||
T0498 | Salsalate | Disalicylic acid,Salicylsalicylic acid,Sasapyrine,NSC-49171 | Reactive Oxygen Species , COX |
Salsalate (Sasapyrine) is an orally available salicylate and non-steroidal anti-inflammatory drug (NSAID), with anti-inflammatory, analgesic and antipyretic activities. | |||
T0157 | Roxatidine Acetate hydrochloride | HOE 760,Roxatidine Acetate HCl | Histamine Receptor |
Roxatidine Acetate hydrochloride (HOE 760) is a specific and competitive histamin H2-receptor antagonist. It inhibits gastric acid secretion and ulcer formation. | |||
T8388 | Vonoprazan | TAK-438 (free base) | Proton pump |
Vonoprazan (TAK-438 (free base)) is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer and reflux esophagitis | |||
T19763 | Cetraxate hydrochloride | DV-1006,DV 1006,Cetraxate HCl,DV1006 | Serine/threonin kinase |
Cetraxate hydrochloride (DV10062) is an oral gastrointestinal medication. It has a cytoprotective effect. | |||
T6566 | Levobupivacaine hydrochloride | Levobupivacaine HCl,(S)-(-)-Bupivacaine HCl,(S)-(-)-Bupivacaine monohydrochloride | Sodium Channel |
Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) is a reversible neuronal sodium channel inhibitor, which is the pure S(-)-enantiomer of bupivacaine. It was utilized as a long-acting local anesthetic... | |||
T21254 | Vonoprazan Fumarate | TAK-438,TAK 438,Vonoprazan Fumurate,TAK438 | Proton pump |
Vonoprazan Fumarate (TAK438) , a novel potassium-competitive acid blocker, inhibits gastric acid secretion. Vonoprazan Fumarate (TAK438) inhibited H+,K+-ATPase activity in porcine gastric microsomes with IC50 value of 19... | |||
T7615 | Xenopsin | Xenopsin(2TFA) | Others |
Xenopsin (Xenopsin(2TFA))(2TFA) is a neurotensin-like octapeptide previously isolated from amphibian skin. |
カタログ番号 | 製品名 | 別名 | ターゲット |
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T5043 | Lentinan | Others | |
Lentinan, isolated and purified from a hot water extract of Lentinula edodes fruit bodies, is a fungal polysaccharide immunomodulator with anti-tumor effects. | |||
T3862 | Irigenin | NF-κB , Integrin | |
Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra Domain A domain. It can sensitize TRAIL-induced apoptosis by enha... | |||
T4034 | Solamargine | Solamargin,δ-Solanigrine | Apoptosis , p38 MAPK , P-gp , STAT |
Solamargine (δ-Solanigrine) is a major steroidal alkaloid glycoside extracted from a traditional Chinese medicine herb, Solanum nigrum L. (SNL); has been shown to inhibit growth and induce apoptosis of various cancer cel... | |||
T4S1881 | Aconine | Jesaconine | Others , NF-κB |
1. Aconine (Jesaconine) is the febrifuge. 2. Aconine possesses gastric anaesthetic props. | |||
T3S0509 | Gaultherin | COX | |
Gaultherin has analgesic, and anti-inflammatory activities.Gaultherin lacks gastric ulcerogenic effect, because of it released salicylate in intestine slowly, not in stomach and it left the cyclooxygenase-1 unaffected, w... | |||
TC0039 | Vasicinone | Others | |
Vasicinone may act as a hepatoprotective agent. (±)-Vasicinone has significant antitussive, expectorant, and bronchodilating activities, which can be used to treat respiratory disease.(S)-Vasicinone exhibits antiprolifer... | |||
T5S2360 | Corydaline | Corydalin,(+)-Corydaline | P450 , Virus Protease , Opioid Receptor , AChE |
1. Corydaline (Corydalin), an isoquinoline alkaloid, is one of the major active constituents in a new prokinetic botanical agent. 2. Corydaline promotes gastric emptying and small intestinal transit and facilitates gastr... | |||
TN6577 | Bletilloside A | 3-Methoxyshancigusin I | Others |
Bletilloside A(3-Methoxyshancigusin I) is a novel glucoside isolated from tubers of striped alfalfa with anti-gastric ulcer activity. | |||
TN2078 | Pinocembrin chalcone | 2',4',6'-Trihydroxychalcone,Pinocembrinchalcone | Calcium Channel , Tyrosinase , Antibacterial , Antifection |
T0743 | DL-Carnitine | Carnitina,Carnitine | Others |
DL-Carnitine (Carnitina) is the constituent of liver and striated muscle. In therapeutically It is used to stimulate pancreatic and gastric secretions and to treat hyperlipoproteinemias. | |||
T2S1975 | Ponicidin | Rubescensine B | Apoptosis , JAK , STAT |
Ponicidin (Rubescensine B) is a diterpenoid derived from Rabdosia rubescens. Ponicidin exhibits immunoregulatory, anti-inflammatory, anti-viral, and anti-cancer activity. Ponicidin induces apoptosis of gastric carcinoma ... | |||
T21651 | Lansoprazole sodium | Lansoprazole (sodium), AG-1749 sodium | Proton pump , Phospholipase , Antibacterial |
Lansoprazole sodium (Lansoprazole (sodium)) is a proton pump inhibitor (PPI) and a potent inhibitor of gastric acidity which is widely used in the therapy of gastroesophageal reflux and peptic ulcer disease. | |||
T20604L | Litorin acetate(55749-97-8 Free base) | Bombesin Receptor | |
Litorin acetate, an amphibian bombesin peptide derivative, is an bombesin receptor agonist. It stimulates the contraction of smooth muscle, stimulates gastrin, gastric acid, and pancreatic secretion, and suppresses the n... | |||
T5S1389 | Escin IB | 5-HT Receptor , NO Synthase | |
Escin Ib inhibits gastric emptying, at least in part, mediated by capsaicin-sensitive sensory nerves, to stimulate the synthesis and/or release of dopamine, to act through central dopamine2 receptor, which in turn causes... | |||
T2203 | D-Carnitine hydrochloride | (S)-Carnitine Hydrochloride,L-Carnitine hydrochloride | Others , Endogenous Metabolite |
D-Carnitine hydrochloride ((S)-Carnitine Hydrochloride) is a constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemi... | |||
T6S2038 | Ziyuglycoside II | Apoptosis , Antioxidant , Reactive Oxygen Species | |
1. Ziyuglycoside II has anti-inflammation and antioxidation properties. 2. Ziyuglycoside II has antibiosis, and homeostasis properties. 3. Ziyuglycoside II has anticancer, and antitumor properties against gastric cancer ... | |||
TN1560 | Dehydroeffusol | 5-Ethenyl-1-Methylphenanthrene-2,7-Diol,Dehydro Effusol | MMP , ERK , GPR , Others |
Dehydroeffusol (Dehydro Effusol) possesses anti-cancer, anxiolytic and sedative properties. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reti... | |||
T0965 | Histamine | Ergamine | 5-HT Receptor , Endogenous Metabolite , Histamine Receptor |
Histamine (Ergamine) is an amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting ne... | |||
TN1103 | Diphyllin | ATPase , Proton pump , Influenza Virus , HIV Protease | |
Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling. | |||
T6534 | Histamine dihydrochloride | peremin,Ceplene,Histamine 2HCl | Endogenous Metabolite , Histamine Receptor |
Histamine dihydrochloride (Ceplene) is dihydrochloride form of Histamine. Histamine is an organic nitrogen compound which is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodila... | |||
T37152 | 3-Methyl-2-cyclopenten-1-one | Endogenous Metabolite | |
3-Methyl-2-cyclopenten-1-one can be used as a food additive to improve the flavor of meat and meat products at 2-5 ppm. Addition of 3-Methyl-2-cyclopenten-1-one showed gastric cytoprotective activity when administered or... | |||
T6S1302 | Carnosol | Nrf2 , Endogenous Metabolite , S6 Kinase | |
Carnosol is an Nrf2 activator, increasing Nrf2 levels and promoting heme oxygenase 1 (HMOX1) expression. It is a ribosomal S6 kinase (RSK2) inhibitor and can be used in gastric cancer-related research with an IC50 value ... | |||
T3727 | Methyl syringate | Syringic Acid Methyl Ester | TRP/TRPV Channel |
Methyl syringate (Syringic Acid Methyl Ester) has a unique inhibitory activity toward aflatoxin production with a different mode of action from that of gallic acid. Methyl syringate from K. pictus is a specific and selec... | |||
T3S2312 | Poncirin | Isosakuranetin-7-neohesperidoside | Apoptosis , Others |
1. Poncirin (Isosakuranetin-7-neohesperidoside) shows a significant in vitro inhibitory effect on the growth of the human gastric cancer cells, SGC-791, in a dose-dependent manner. 2. Poncirin prevents adipogenesis, enha... | |||
T2A2532 | L-Histidine | Glyoxaline-5-alanine,L-(-)-Histidine,histidine,L-Hisidine | Mitochondrial Metabolism , Endogenous Metabolite |
L-Histidine (L-(-)-Histidine) is a semi-essential amino acid (children should obtain it from food) needed in humans for growth and tissue repair, L-Histidine is important for maintenance of myelin sheaths that protect ne... | |||
T40615 | N,N'-Dimethylthiourea | DMTU | Antioxidant |
N,N'-Dimethylthiourea (DMTU) (DMTU), isolated from Allii Sativi Bulbus, is an orally active scavenger of hydroxyl radical ( OH) and blocks OH production by activated neutrophils in vitro. N,N'-Dimethylthiourea protects a... | |||
T4S0867 | Pogostone | DHELWANGIN | Apoptosis , Antibacterial , Autophagy |
1. Pogostone (DHELWANGIN) possesses potent anti-bacterial and anti-fungal activities, such as gram negative bacteria , gram positive bacteria, Escherichia coli. 2. Pogostone exhibits an immunosuppressive property by dire... | |||
T0962 | L-Hyoscyamine | Daturine,Hyoscyamine | AChR |
L-Hyoscyamine (Daturine) functions as a non-selective, competitive antagonist of muscarinic receptors, thereby inhibiting the parasympathetic activities of acetylcholine on the salivary, bronchial, and sweat glands, as w... | |||
TN2601 | 12-O-Methylcarnosic acid | Reductase | |
12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from Salvia microphylla, is an active constituent of 5α-Reductase inhibition with an IC50 value of 61.7 μM. 12-O-Methylcarnosic acid has Antioxidant activity... | |||
T4S1619 | L-Hyoscyamine sulfate | Hyoscyamine sulfate hydrate,Levsin Sulfate,Hyoscyamine Sulphate | AChR |
L-Hyoscyamine sulfate (Levsin Sulfate) is the sulfate salt of a belladonna alkaloid derivative and the levorotatory form of racemic atropine isolated from the plants Hyoscyamus niger or Atropa belladonna, which exhibits ... | |||
T3S2344 | β,β-Dimethylacrylshikonin | Dimethylacrylshikonin,β, β-Dimethylacrylshikonin | ERK , HIF/HIF Prolyl-Hydroxylase |
1. β,β-Dimethylacrylshikonin (Dimethylacrylshikonin) is a promising agent for developing an improved strategy for radiotherapy against tumors. (a) Injection of Dimethylacrylshikonin combined with IR treatment significant... | |||
T3779 | Crocin II | Crocin 2,Crocetin gentiobiosylglucosyl ester,Tricrocin,Crocin B | Caspase , COX , NO Synthase |
Crocin II (Crocetin gentiobiosylglucosyl ester) has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect of crocin is mainly mediated by reducing the protein expres... | |||
T6S1684 | 8-Gingerol | Antioxidant , Antibacterial , TRP/TRPV Channel | |
1. 8-Gingerol has antioxidant activity. 2. 8-Gingerol has antimycobacterial activity. 3. 8-Gingerol could be used as an effective skin-whitening agent. 4. 8-Gingerol shows antipyretic and anti-inflammation characteristic... | |||
T4S0797 | Berberine | Berberin,Umbellatine | Reactive Oxygen Species , Topoisomerase , Endogenous Metabolite , Antibacterial , Antibiotic , Autophagy |
1. Berberine (Umbellatine) is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism. 2. Berberine may as a broad-spectrum anti-microbial medicine, a complementary therapeutic agent for HIV/AIDS. 3.... | |||
TN4932 | Sageone | PARP , Akt , Caspase , Antifection | |
Sageone represents a promising anticancer agent against gastric cancer that warrants further study, it synergizes with cisplatin cytotoxicity in SNU-1 human gastric cancer cells.Sageone also shows antiviral activity. | |||
T20604 | Litorin | ||
Litorin, an amphibian bombesin peptide derivative, is found to suppress the nutriment, to stimulate the contraction of smooth muscle, to stimulate gastrin, gastric acid, and pancreatic secretion. | |||
TN3605 | Casegravol | Others | |
Casegravol shows antiproliferative activity against human gastric adenocarcinoma (MK-1), human uterus carcinoma (HeLa), and murine melanoma (B16F10) cells. | |||
TN4465 | Luvangetin | COX , Prostaglandin Receptor , Antifection | |
Luvangetin may have anti-inflammatory activity, it can inhibit NO and PGE2 production in LPS-stimulated BV2 cells. Luvangetin shows significant protection against pylorus-ligated and aspirin-induced gastric ulcers in rat... | |||
TN1302 | 6,8-Diprenylorobol | Others , HIV Protease , Antifection | |
6,8-Diprenylorobol possesses weaker anti-H. pylori activity, it may be a useful chemopreventive agent for peptic ulcer or gastric cancer in H. pylori-infected individuals. | |||
TN1810 | Jatropholone B | Others | |
Jatropholone B shows antiproliferative activity against cancer cell lines. It also has gastroprotective activity in preventing the gastric lesions in mice. | |||
TN3740 | Cyclocommunol | PAFR | |
Cyclocommunol exhibits cytotoxicity against hepatocellular carcinoma (SMMC-7721) and gastric carcinoma (BGC-823 and SGC-7901) cell lines. It also shows strong inhibition of arachidonic acid (AA)- and collagen-induced pla... | |||
TN4489 | Manassantin A | ERK , cAMP , TNF , NF-κB , MAPK , COX , HIF , Prostaglandin Receptor , JNK , STAT | |
Manassantin A is a high potent HIF-1 inhibitor, it protects the gastric mucosa from ethanol-induced acute gastric injury, and suggest that these protective effects might be associated with COX/PGE2 stimulation, inhibitio... | |||
TN3852 | Dihydrolicoisoflavone | Antifection | |
Dihydrolicoisoflavone A possesses weaker anti-H. pylori activity, it may be useful chemopreventive agents for peptic ulcer or gastric cancer in H. pylori-infected individuals. | |||
T83257 | 7(8)-Dehydroschisandrol A | ||
7(8)-Dehydroschisandrol A (Compound 4a), a lignan extracted from Schizandra chinensis Baill, exhibits a mild inhibitory activity against stress-induced gastric ulcers [1]. | |||
T83258 | 7(18)-Dehydroschisandro A | ||
7(18)-Dehydroschisandro A (Compound 2), a lignan isolated from Schizandra chinensis Baill, exhibits inhibitory effects on stress-induced gastric ulcers [1]. | |||
T80702 | α-Thevetin B | ||
α-Thevetin B (Compound 24), a cardiac glycoside extracted from Thevetia peruviana, has applications in research concerning lung, gastric, and pancreatic cancers [1]. | |||
TN3726 | Cudraflavone B | IκB/IKK , MAO , ROS , Akt , COX , PI3K , Nrf2 , Autophagy | |
Cudraflavone B has anti-proliferative activity, mouse brain monoamine oxidase (MAO) inhibitory effects, apoptotic actions in human gastric carcinoma cells and mouse melanoma cells, and hepatoprotective activity. It may b... | |||
TN3495 | Benzyl ferulate | TNF , Antifection | |
Benzyl ferulate has antimicrobial activity. It also shows good anti-proliferative against three gastro-intestinal cancer cell lines(HCT-116 colon carcinoma, KYSE-30 oesophageal squamous cancer, and NCI-N87 gastric carcin... | |||
TN6010 | Picrasidine S | ||
Picrasidine S shows the potent cytotoxicity against human HeLa cervical, gastric MKN-28, and mouse melanoma B-16 cancer cells, it also shows the potent antibacterial activity against two strains of pathogenic bacteria me... | |||
TN1913 | Marmin | Calcium Channel , Antifection , Histamine Receptor | |
Marmin have anti-ulcer effects, which are ascribed primarily to the maintenance of the mucosal barrier integrity and inhibition of gastric motor activity and secondarily due to the prevention of the effects of endogenous... | |||
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カタログ番号 | 製品名 | Species | Expression System |
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TMPY-03221 | Intrinsic Factor Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Gastric intrinsic factor, also known as GIF, belongs to the of the cobalamin transport protein family. It is a glycoprotein produced by the parietal cells of the stomach. Gastric intrinsic factor plays a key role in the ... | |||
TMPY-00319 | GIP Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Glucose-dependent insulinotropic polypeptide (GIP) is an incretin that plays an important role in fat accumulation. GIP is involved in fat accumulation and insulin resistance with aging. Glucose-dependent insulinotropic ... | |||
TMPY-04079 | LIPF Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
LIPF Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 44.6 kDa and the accession number is AAI12273.1. | |||
TMPJ-01061 | Nucleobindin-2 Protein, Human, Recombinant | Human | E. coli |
Nesfatin-1 is a metabolic polypeptide encoded in the N-terminal region of the precursor protein, Nucleobindin2 (NUCB2). Nesfatin-1 is a neuropeptide produced in the hypothalamus of mammals. It participates in the regulat... | |||
TMPH-01892 | ATP4A Protein, Human, Recombinant (His & Myc) | Human | E. coli |
ATP4A Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 54.6 kDa and the accession number is P20648. | |||
TMPH-01893 | ATP4B Protein, Human, Recombinant (GST) | Human | E. coli |
ATP4B Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 53.6 kDa and the accession number is P51164. | |||
TMPH-01894 | ATP4B Protein, Human, Recombinant | Human | E. coli |
ATP4B Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 26.6 kDa and the accession number is P51164. | |||
TMPJ-00320 | AMIGO2 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Amphoterin-Induced Protein 2 (AMIGO2) is a single-pass type I membrane protein which belongs to the AMIGO family of immunoglobulin superfamily. Mature AMIGO2 contains an Ig-like C2-type (immunoglobulin-like) domain, 6 LR... | |||
TMPJ-00953 | ADH7 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Alcohol dehydrogenase class 4 mu/sigma chain (ADH7) is a cytoplasm enzyme which is a member of the alcohol dehydrogenase family. The expression of this gene makes it much more abundant in the stomach than the liver, thus... | |||
TMPY-04779 | BTN3A2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the function of T cells. BTN3A2 is overexpressed in gastric tu... | |||
TMPY-02292 | IGSF11 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Immunoglobulin superfamily member 11(IGSF11) is expressed on the plasma membrane in the testis and brain. These IGSF proteins undergo final modifications during capacitation and/or the acrosome reaction. IGSF proteins sh... | |||
TMPY-01897 | PRSS3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains on... | |||
TMPY-01442 | DMBT1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB d... | |||
TMPY-00519 | Gastrokine 1 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Gastrokine 1 (GKN1) belongs to the BRICHOS domain family and plays a major role in maintaining gastric mucosa integrity. GKN1 is highly expressed in gastric tissue and is secreted into the stomach but is not expressed in... | |||
TMPK-00529 | EPHA5 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Ephrin type-A receptor 5 (EphA5) expression was detected in all non-tumor gastric epithelia but was differentially expressed among gastric cancer samples. EphA5 is differentially expressed in gastric cancer. EphA5 may th... | |||
TMPK-00899 | EPHA5 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Ephrin type-A receptor 5 (EphA5) expression was detected in all non-tumor gastric epithelia but was differentially expressed among gastric cancer samples. EphA5 is differentially expressed in gastric cancer. EphA5 may th... | |||
TMPH-00800 | UreA Protein, Helicobacter pylori, Recombinant (His) | Helicobacter pylori | P. pastoris (Yeast) |
Ammonia produced by ureolysis increases the gastric pH thereby providing an environment permissive for colonization of the stomach. | |||
TMPK-01019 | EPHA5 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
The aim of the present study was to evaluate ephrin type-A receptor 5 (EphA5) expression and its clinicopathological significance in gastric cancer. Gastric cancer tissues were analyzed by immunohistochemistry. The assoc... | |||
TMPH-02298 | Urocortin-3 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress. | |||
TMPJ-01079 | TFF2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Recombinant Murine TFF-2 is an 11.9 kDa polypeptide of 106 amino acid residues, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds. The Trefoil Factor peptides (TFF1, T... | |||
TMPJ-01089 | TFF1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Trefoil Factor 1 (TFF1) belongs to the three structurally related secreted proteins that contain trefoil domains.TFF1 is an approximately peptide that has an important effect in epithelial regeneration and wound healing... | |||
TMPK-01304 | Kremen-2 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Kremen2 (Krm2) plays an important role in embryonic development, bone formation, and tumorigenesis as a crucial regulator of classical Wnt/β-catenin signaling pathway. Compared to para-cancerous tissues, Krm2 was signifi... | |||
TMPK-01106 | Kremen-2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Kremen2 (Krm2) plays an important role in embryonic development, bone formation, and tumorigenesis as a crucial regulator of classical Wnt/β-catenin signaling pathway. Compared to para-cancerous tissues, Krm2 was signifi... | |||
TMPK-01093 | Kremen-2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Kremen2 (Krm2) plays an important role in embryonic development, bone formation, and tumorigenesis as a crucial regulator of classical Wnt/β-catenin signaling pathway. Compared to para-cancerous tissues, Krm2 was signifi... | |||
TMPH-00802 | VacA Protein, Helicobacter pylori, Recombinant (His & SUMO) | Helicobacter pylori | E. coli |
Induces vacuolation of eukaryotic cells. Causes ulceration and gastric lesions. vacA Protein, Helicobacter pylori, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted m... | |||
TMPK-01076 | GPA34/VSIG1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
VSIG1, a cell adhesion protein of the immunoglobulin superfamily, is preferentially expressed in stomach, testis, and certain gastric, esophageal and ovarian cancers. Here, we describe the expression patterns of three al... | |||
TMPK-01160 | GPA34/VSIG1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
VSIG1, a cell adhesion protein of the immunoglobulin superfamily, is preferentially expressed in stomach, testis, and certain gastric, esophageal and ovarian cancers. Here, we describe the expression patterns of three al... | |||
TMPJ-01078 | TFF2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Trefoil Factor 2 (TFF2) is a member of the trefoil family and contains two P-type (trefoil) domains. Members of this family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that ... | |||
TMPH-02522 | GHRL Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid se... | |||
TMPH-00801 | UreB Protein, Helicobacter pylori, Recombinant (His) | Helicobacter pylori | E. coli |
Ammonia produced by ureolysis increases the gastric pH thereby providing an environment permissive for colonization of the stomach. UreB Protein, Helicobacter pylori, Recombinant (His) is expressed in E. coli expression ... | |||
TMPY-03979 | ARHI Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
ARHI, also known as DIRAS3, belongs to the small GTPase superfamily, Di-Ras family. ARHI gene is a novel tumor suppressor gene located on chromosome 1p31. Downregulation of ARHI expression has been detected in many types... | |||
TMPH-00799 | UreA Protein, Helicobacter pylori, Recombinant (E. coli, His) | Helicobacter pylori | E. coli |
Ammonia produced by ureolysis increases the gastric pH thereby providing an environment permissive for colonization of the stomach. UreA Protein, Helicobacter pylori, Recombinant (E. coli, His) is expressed in E. coli ex... | |||
TMPY-02581 | STAT4 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
High expression of STAT4 in gastric cancer predicted a better clinical outcome. STAT4 might be a useful biomarker to identify patients at high risk of recurrence after gastrectomy. Genetic variants in the transcription f... | |||
TMPK-00743 | LGR-5 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
G protein-coupled receptor 5 (LGR5), known as a stem cell marker for colon cancer and gastric cancer, can serve as a novel GSC marker involved in EMT and a therapeutic target in glioma.LGR5 is a new functional GSC marker... | |||
TMPJ-01028 | Claudin-18.2 Protein, Human, Recombinant (Twin strep & Flag) | Human | HEK293 Cells |
Claudin-18 (CLDN18) is a protein that in humans is encoded by the CLDN18 gene. It belongs to the group of claudins. CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial ... | |||
TMPK-01152 | CHRDL1 Protein, Human, Recombinant (His) | Human | E. coli |
CHRDL1 (Chordin-like 1) is a secreted protein that acts as an antagonist of bone morphogenetic protein (BMP). BMP plays a role as an activator of BMP receptor II (BMPR II), which mediates extracellular to intracellular s... | |||
TMPJ-00265 | Serpin F1 Protein, Mouse, Recombinant | Mouse | E. coli |
Serpin F1 is secreted Neurotrophic protein and belongs to the serpin family. Serpin F1 Highly expressed in the liver, gastric glandular mucosa and renal tubules. It is also expressed in the brain, heart, lung retina and ... | |||
TMPK-00891 | GIP Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
The potential application of glucose-dependent insulinotropic polypeptide (gastric inhibitory polypeptide, GIP) in the management of obesity and type 2 diabetes has been controversial. Initial interest in the therapeutic... | |||
TMPK-00728 | PSCA Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Gastric cancer is a deadly malignancy and is a prognostically unfavorable entity with restricted therapeutic strategies available. Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored cell s... | |||
TMPK-00890 | GIP Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
The potential application of glucose-dependent insulinotropic polypeptide (gastric inhibitory polypeptide, GIP) in the management of obesity and type 2 diabetes has been controversial. Initial interest in the therapeutic... | |||
TMPK-00036 | GIP Protein, Human, Recombinant (His) | Human | HEK293 Cells |
The potential application of glucose-dependent insulinotropic polypeptide (gastric inhibitory polypeptide, GIP) in the management of obesity and type 2 diabetes has been controversial. Initial interest in the therapeutic... | |||
TMPY-03795 | EIF5A2 Protein, Human, Recombinant (His) | Human | E. coli |
Eukaryotic translation initiation factor 5A2 (EIF5A2) has been demonstrated to be upregulated in numerous types of human cancer and is associated with cancer progression. Silencing of EIF5A2 in the NSCLC cells resulted i... | |||
TMPK-00906 | PSCA Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Gastric cancer is a deadly malignancy and is a prognostically unfavorable entity with restricted therapeutic strategies available. Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored cell s... | |||
TMPJ-01288 | KLF6 Protein, Human, Recombinant | Human | E. coli |
Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by ... | |||
TMPJ-01456 | Mucin-17/MUC17 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Mucins are key components of the mucosal barrier in the stomach that protects epithelia from carcinogenic effects of chronic inflammation. Analysis of The Cancer Genome Atlas database indicated that mucin17 (MUC17) was m... | |||
TMPJ-00500 | Kappa-Casein Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Kappa-Casein (CSN3) is a secreted protein that belongs to the Kappa-Casein family. CSN3 exists in heteromultimers that are composed of alpha-s 1casein and kappa casein linked by disulfide bonds. CSN3 is involved in a nu... | |||
TMPJ-00701 | Carbonic Anhydrase 11 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Carbonic Anhydrase-Related Protein 11 (CA11) is a secreted protein member of the α-carbonic anhydrase family. Carbonic Anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of ... | |||
TMPY-01877 | CA5A Protein, Human, Recombinant (His) | Human | E. coli |
Carbonic anhydrase 5A, mitochondrial, also known as Carbonate dehydratase VA, Carbonic anhydrase VA, CA-VA and CA5A, is a member of thealpha-carbonic anhydrase family. Carbonic anhydrases (CAs) are a large family of z... | |||
TMPY-02277 | Carbonic Anhydrase 7 Protein, Human, Recombinant (His) | Human | E. coli |
Carbonic anhydrase 7, also known as carbonate dehydratase VII, carbonic anhydrase VII, CA-VII and CA7, is a cytoplasm protein which belongs to thealpha-carbonic anhydrase family. Carbonic anhydrases are a large family... | |||
TMPJ-00529 | FABP6 Protein, Human, Recombinant (His) | Human | E. coli |
Fatty Acid-Binding Protein 6 (FABP6) is cytoplasmic protein that binds long-chain fatty acids and other hydrophobic ligands which belongs to the calycin superfamily. FABP6 expression is restricted in the small intestine ... | |||
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カタログ番号 | 製品名 | ||
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L6600 | Anti-Gastroenteritis Natural Product Library | 219 compounds | |
A unique collection of 219 natural products related to gastroenteritis for high throughput screening (HTS) and high content screening (HCS); |