検索結果

Search Results for " inactive "

ターゲット

185

阻害剤

天然化合物

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T23150	PHGDH-inactive		Others
	inactive analog of the 3-phosphoglycerate dehydrogenase (PHGDH) inhibitors NCT-502 and NCT-503		Others
T36580	Glucagon Receptor Antagonist Inactive Control
	Glucagon Receptor Antagonist Inactive Control is a Glucagon receptor antagonist that can be used in related research in the field of life sciences. Its product number is T36580 and CAS number is 362482-00-6.
T35059	VinSpinIC	Vinnie's Spindlin Inactive Control,TD020826a
	VinSpinIC is an inactive control for VinSpinIn.
TMIH-0316	Lurasidone Inactive Metabolite 14326-d8	5β/6β-Hydroxy Lurasidone-d8 Hydrochloride (Mixture of Diastereomers)
	Lurasidone Inactive Metabolite 14326-d8 is a deuterated compound of Lurasidone Inactive Metabolite 14326.Lurasidone Inactive Metabolite 14326 has a CAS number of 186204-33-1.
TMIH-0315	Lurasidone Inactive Metabolite 14283-d8	5α/6α-Hydroxy Lurasidone-d8 Hydrochloride (Mixture of Diastereomers)
	Lurasidone Inactive Metabolite 14283-d8 is a deuterated compound of Lurasidone Inactive Metabolite 14283.Lurasidone Inactive Metabolite 14283 has a CAS number of 186204-31-9.
T7414	ARS-853		Apoptosis , Raf , Ras
	ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cells		Apoptosis , Raf , Ras
T8543	KN-92 hydrochloride		CaMK
	KN-92 hydrochloride is an inactive derivative of KN-93. KN-93 is a selective Ca2+/calmodulin-dependent kinase II (CaMKII) inhibitor, competitively blocking CaM binding to the kinase with Ki of 370 nM.		CaMK
T9303	MRTX1133		Ras
	MRTX1133 is a KRAS G12D inhibitor (KD=0.2 pM) that is potent, selective, and non-covalent. MRTX1133 exhibits inhibitory activity against KRAS G12D-mutated tumors, but not against KRAS wild-type tumors.		Ras
T22026	AGK7		Others , Sirtuin
	AGK7 is an inactive control of AGK2, a selective SIRT2 inhibitor that selectively inhibits SIRT3 over SIRT1 and SIRT2 (IC50 = >5 μM, >50 μM and >50 μM for SIRT3, SIRT1, and SIRT2, respectively).		Others , Sirtuin
T8369	Adagrasib	MRTX849	Ras
	Adagrasib (MRTX849) is an orally active and selective covalent inhibitor of KRAS G12C. Adagrasib binds to the GDP state of the inactive conformation of KRAS G12C and inhibits KRAS and its downstream signaling. Adagrasib ...		Ras
T4530	KN-92 phosphate	KN92-H3PO4	CaMK
	KN-92 phosphate (KN92-H3PO4) is an inactive derivative of KN-93. KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM).		CaMK
T15441	GSK8573		Epigenetic Reader Domain
	GSK8573 is an inactive control compound for GSK2801. GSK8573 has binding activity to BRD9 (Kd of 1.04 μM).		Epigenetic Reader Domain
T16032L	(Z)-MDL 105519		Others
	(Z)-MDL 105519 is an inactive isomer of MDL105519.		Others
T22933L	LRGILS-NH2 acetate		Protease-activated Receptor
	LRGILS-NH2 acetate is a PAR-2-inactive reversed peptide.		Protease-activated Receptor
T39979	(S)-ErSO		Others
	(S)-ErSO is an inactive dextrorotatory enantiomer of ErSO.		Others
T7790	Bisindolylmaleimide V		PKC , S6 Kinase
	Bisindolylmaleimide V, a bisindolylmaleimide derivative, is an inactive of a kinase inhibitor.		PKC , S6 Kinase
T27404L	Isomer-GAT 107		Others
	isomer-GAT 107 ((-)GAT 107) is an inactive isomer of (+)GAT 107.		Others
T20075	Sodium dodecyl sulfate	Laurylsulfuric acid sodium salt,NSC 402488,Anticerumen,NSC-402488,NSC402488,Natrium laurylsulfuricum,Sodium dodecylsulfate,Sodium lauryl sulfate	Others
	Sodium dodecyl sulfate(Sodium lauryl sulfate) is a pharmaceutical excipient that is biologically inactive and improves the stability, solubility and processability of pharmaceutical preparations.		Others
T13507	4,4'-Iminodiphenol	Leucoindophenol	Estrogen/progestogen Receptor
	4,4'-Iminodiphenol (Leucoindophenol) is an inactive estrogen receptor ligand with a diphenylamine backbone.		Estrogen/progestogen Receptor
T15444	GSK962		Others
	GSK962 is a GSK963 inactive enantiomer. It can be used to confirm the on-target effects.		Others
T0008	Phenytoin sodium	5,5-Diphenylhydantoin sodium salt,Diphantoine,Dilantin sodium,Diphenylhydantoin Sodium	Virus Protease , Sodium Channel
	Phenytoin sodium (Diphantoine) is an inactive stabilizer for voltage-gated sodium channel .		Virus Protease , Sodium Channel
T12503	(+)-Blebbistatin		Others
	(+)-Blebbistatin is the inactive enantiomer of (–)-Blebbistatin. (–)-Blebbistatin is a selective myosin II ATPase inhibitor.		Others
T6725	VU 0357121		GluR
	VU0357121, a positive allosteric modulator of mGlu5 (EC50: 33 nM), is inactive or very weakly antagonizing at other mGlu receptor subtypes.		GluR
T22148	(S)-Lisofylline		Others
	(S)-Lisofylline is the inactive optical enantiomer of (R)-lisofylline which is an anti-inflammatory agent. (S)-Lisofylline is exclusively converted to pentoxifylline in human liver microsomes.		Others
T35544	ML115		STAT
	ML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of 2.0 nM, and is inactive against the related STAT1 and NFκB anti-targets.		STAT
T13411	ZLN024		AMPK
	ZLN024 is an activator of AMPK allosteric. ZLN024 allosterically stimulates active AMPK heterotrimers and the inactive α1 subunit truncations α1 (1-394) and α1 (1-335) but not α1 (1-312).		AMPK
T23101	O-3M3FBS		Others
	Inactive analog of m-3M3FBS (PLC activator)		Others
T9848	GSK2850163 (S enantiomer)		IRE1
	GSK2850163 (S enantiomer) is the inactive enantiomer of GSK2850163. GSK2850163 is an novel inhibitor of inositol-requiring enzyme-1 alpha (IRE1a).		IRE1
T24677	PS47	PS 47,PS-47	PDK
	PS-47(PS 47) is an inactive E-isomer of PS48. PS48 is an activator of PDK1.		PDK
T3558	EBE-A22	PD153035 Analog 63	EGFR
	EBE-A22 (PD153035 Analog 63) is a derivative of PD 153035 which can inhibit ErbB-1-phosphorylation, whereas EBE-A22 is inactive.		EGFR
T19578	TH-263		Others
	TH-263 is inactive toward both LIMK1 and LIMK2 and thus can be used as negative control for TH-257, and is a diaryl sulfonamide derivative.		Others
T2105	Veliparib dihydrochloride	ABT-888 dihydrochloride	PARP , Autophagy
	Veliparib dihydrochloride (ABT-888 dihydrochloride) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively. It is inactive to SIRT2.		PARP , Autophagy
T5938	4-Phenoxybenzylamine		HCV Protease
	4-Phenoxybenzylamine inhibits the function of the NS3 protein by stabilizing an inactive conformation with an IC50 of about 500 μM against HCV NS3/4a .		HCV Protease
T10800	CHMFL-ABL-121		Bcr-Abl
	CHMFL-ABL-121 is a highly potent inhibitor of type II ABL kinase (IC50s: 2 nM and 0.2 nM against purified inactive ABL wt and T315I kinase protein).		Bcr-Abl
T37445	Etanercept		TNF
	Etanercept is a dimeric fusion protein that serves as a competitive TNF inhibitor by binding to TNF. It effectively inhibits the binding of both TNF-α and TNF-β to the TNF receptors on cell surfaces, thereby rendering TN...		TNF
T5440	Dbet57		Epigenetic Reader Domain
	dBET57 is heterobifunctional degrader of BRD4 based on the PROTAC technology, exhibits significant degradation of BRD4BD1 with a DC50/5h of 500 nM ,and inactive on BRD4BD2		Epigenetic Reader Domain
T6312	R547	Ro 4584820	Apoptosis , GSK-3 , PKA , CDK
	R547 (Ro 4584820) is a potent ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 nM/1 nM. It is less potent to CDK7 and GSK3α/β, while inactive to other kinases. Phase 1.		Apoptosis , GSK-3 , PKA , CDK
T41162	ZLN 024 hydrochloride		AMPK
	ZLN 024 hydrochloride is an AMPK allosteric activator and stimulates the inactive α1 subunit truncations α1 (1-394) and α1 (1-335) but not α1 (1-312).		AMPK
T6932	PD168393		Apoptosis , EGFR , FGFR , IGF-1R , PDGFR , PKC , Autophagy
	PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.		Apoptosis , EGFR , FGFR , IGF-1R , PDGFR , PKC , Autophagy
T6266	PP2	AGL 1879,AG 1879,AGL 1879	EGFR , Tyrosine Kinases , JAK , Src
	PP2 (AG 1879,AGL 1879) is a effective inhibitor of Lck/Fyn (IC50:4/5 nM) , ~100-fold less potent to EGFR, inactive for ZAP-70, PKA and JAK2.		EGFR , Tyrosine Kinases , JAK , Src
T22106	MLS-573151		CDK , Ras
	MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM). It is inactive against other GTPases family members, such as Rab2, Rab7, H-Ras, Rac1, Rac 2 and RhoA wild-type. MLS-573151 acts by blocking the binding...		CDK , Ras
T15500	HPi1		Others , Antibacterial
	HPi1 is a selective and orally active antimicrobial against Helicobacter pylori (IC50: 0.24 μM and a MIC of 0.08-0.16 μg/mL). HPi1 is inactive against other Xaliproden, including the gut commensals, Lactobacillus reuteri...		Others , Antibacterial
T9095	Necrostatin-34	2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4	RIP kinase
	Necrostatin-34 (2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4) is a RIPK1 kinase inhibitor, stabilizing RIPK1 kinase in an inactive conformation by occupying a distinct binding pocket in the kinase domain.		RIP kinase
T22775	Exo-IWR-1	exo-IWR 1	Wnt/beta-catenin
	exo-IWR-1 (exo-IWR 1) is an inactive stereoisomer of Endo-IWR-1,and is a negative control of IWR-1. IWR-1 is a tankyrase inhibitor which inhibits Wnt/β-catenin signaling pathway.		Wnt/beta-catenin
T1502	Vildagliptin	NVP-LAF 237,LAF237	Apoptosis , Ferroptosis , Proteasome , DPP-4
	Vildagliptin (LAF237) is a cyanopyrrolidine-based, orally bioavailable inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Vildagliptin's cyano moiety undergoes hydrolysis and this inactive metabolit...		Apoptosis , Ferroptosis , Proteasome , DPP-4
T14984	CLP257		Potassium Channel
	CLP257 is a selective K+-Cl− cotransporter KCC2 activator (EC50: 616 nM) and it is inactive against NKCC1, GABAA receptors, KCC1, KCC3 or KCC4. CLP257 alleviates hypersensitivity in rats with neuropathic painc and it al...		Potassium Channel
T10608	BRD5648	(R)-BRD0705	GSK-3
			GSK-3
T21782	A 77636 hydrochloride	A77636 hydrochloride	Dopamine Receptor
	A 77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM). A 77636 hydrochloride shows antiparkinsonian activity. A 77636 hydrochloride is functionall...		Dopamine Receptor
TP1359L	Amyloid β Peptide (42-1)(human) acetate	Amyloid β Peptide (42-1)(human) acetate(317366-82-8 free base)	Beta Amyloid
	Amyloid β Peptide (42-1)(human) acetate is the inactive form of Amyloid β Peptide (1-42). Amyloid β Peptide (42-1)(human) acetate is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease...		Beta Amyloid
T10826	CK-666		HIV Protease , Microtubule Associated
	CK-666 is a cell-permeable inhibitor of actin-related protein Arp2/3 complex. It binds to the Arp2/3 complex, stabilizes the inactive state of the complex, blocking the movement of the Arp2 and Arp3 subunits into the act...		HIV Protease , Microtubule Associated

Compounds

Glucagon Receptor Antagonist Inactive Control

Synonym: Vinnie's Spindlin Inactive Control,TD020826a

Target:

Lurasidone Inactive Metabolite 14326-d8

TMIH-0316

Synonym: 5β/6β-Hydroxy Lurasidone-d8 Hydrochloride (Mixture of Diastereomers)

Target:

Lurasidone Inactive Metabolite 14283-d8

TMIH-0315

Synonym: 5α/6α-Hydroxy Lurasidone-d8 Hydrochloride (Mixture of Diastereomers)

Target: Apoptosis, Raf, Ras

Target: Others, Sirtuin

Target: Epigenetic Reader Domain

Target: Protease-activated Receptor

Bisindolylmaleimide V

T7790

Synonym:

Target: PKC, S6 Kinase

Sodium dodecyl sulfate

T20075

Synonym: Laurylsulfuric acid sodium salt,NSC 402488,Anticerumen,NSC-402488,NSC402488,Natrium laurylsulfuricum,Sodium dodecylsulfate,Sodium lauryl sulfate

Target: Others

4,4'-Iminodiphenol

T13507

Synonym: Leucoindophenol

Target: Estrogen/progestogen Receptor

Synonym: 5,5-Diphenylhydantoin sodium salt,Diphantoine,Dilantin sodium,Diphenylhydantoin Sodium

Target: Virus Protease, Sodium Channel

GSK2850163 (S enantiomer)

Synonym: PD153035 Analog 63

Veliparib dihydrochloride

T2105

Synonym: ABT-888 dihydrochloride

Target: PARP, Autophagy

Target: Epigenetic Reader Domain

R547

T6312

Synonym: Ro 4584820

Target: Apoptosis, GSK-3, PKA, CDK

ZLN 024 hydrochloride

Target: Apoptosis, EGFR, FGFR, IGF-1R, PDGFR, PKC, Autophagy

PP2

T6266

Synonym: AGL 1879,AG 1879,AGL 1879

Target: EGFR, Tyrosine Kinases, JAK, Src

Target: Others, Antibacterial

Necrostatin-34

T9095

Synonym: 2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4

Target: Wnt/beta-catenin

Vildagliptin

T1502

Synonym: NVP-LAF 237,LAF237

Target: Apoptosis, Ferroptosis, Proteasome, DPP-4

CLP257

T14984

Synonym:

Target: Potassium Channel

A 77636 hydrochloride

T21782

Synonym: A77636 hydrochloride

Target: Dopamine Receptor

Amyloid β Peptide (42-1)(human) acetate

TP1359L

Synonym: Amyloid β Peptide (42-1)(human) acetate(317366-82-8 free base)

Target: HIV Protease, Microtubule Associated

カタログ番号	製品名	別名	ターゲット
TQ0288	Hexahydrocurcumin		Reactive Oxygen Species , ROS , COX
	Hexahydrocurcumin is a selective, orally active COX-2 inhibitor and inactive against COX-1.		Reactive Oxygen Species , ROS , COX
T1238	Daidzein	Isoflavone	Endogenous Metabolite , PPAR
	Daidzein (Isoflavone) is an isoflavone extract from soy, which is an inactive analog of the tyrosine kinase inhibitor genistein. It has antioxidant and phytoestrogenic properties.		Endogenous Metabolite , PPAR
TN6798	Progoitrin		Others
	Progoitrin is a biochemical from the glucosinolate family that is found in some food, which is inactive but after ingestion is converted to goitrin. Goitrin decreases the thyroid hormone production. Apart from goitrin, p...		Others
T36857	Estrone sulfate sodium	Estrone 3-sulfate (sodium salt),17β-Estrone 3-sulfate	Endogenous Metabolite
	Estrone sulfate sodium (17β-Estrone 3-sulfate) is an endogenous steroid and an estrogen ester that is biologically inactive. It is converted by steroid sulfatase into estrone . Estrone sulfate sodium has been investigate...		Endogenous Metabolite
T4710	3-Methoxytyramine hydrochloride	3-O-methyl Dopamine hydrochloride,3-O-methyl Dopamine hydrochloride)	Others , Endogenous Metabolite , Drug Metabolite
	3-Methoxytyramine hydrochloride (3-O-methyl Dopamine hydrochloride) is an inactive metabolite of dopamine which can activate trace amine associated receptor 1 (TAAR1). 3-methoxytyramine can be found primarily in human br...		Others , Endogenous Metabolite , Drug Metabolite
T1688	Pregnanediol	5Beta-Pregnane-3Alpha,20alpha-Diol,Pregnandiol	Estrogen/progestogen Receptor , Endogenous Metabolite
	Pregnanediol (5Beta-Pregnane-3Alpha,20alpha-Diol) is an inactive metabolite of PROGESTERONE by reduction at C5, C3, and C20 position. Pregnanediol(5Beta-Pregnane-3Alpha,20alpha-Diol) has two hydroxyl groups, at 3-alpha a...		Estrogen/progestogen Receptor , Endogenous Metabolite
T6491	(-)-(S)-Equol	(−)-Equol,Equol,4',7-Dihydroxyisoflavan,4',7-Isoflavandiol	Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Endogenous Metabolite
	(-)-(S)-Equol (4',7-Dihydroxyisoflavan) is an orally bioavailable, non-steroidal estrogen naturally produced by the metabolism of the isoflavonoid daidzein by human intestinal microflora, with potential chemoprotective a...
TN4428	Lethedoside A		Others
	Lethedoside A has inactive or weakly active against KB tumor cells.		Others
T25240	Chloramphenicol succinate	Paraxin succinate,Kemicetine succinate,CPSA
	Chloramphenicol succinate is an inactive precursor of chloramphenicol. It is used for parenteral administration of chloramphenicol.
T19565	Streptolysin O		Others
	Streptolysin O causes both lysis of cells and cardiotoxicity. Streptolysin O is widely used for the controlled permeabilization of cell membranes. Streptolysin O exists in two forms, a reduced active state and an oxidize...		Others
TN2750	2-C-Methyl-D-erythrono-1,4-lactone		Others
	(-)-2-C-Methyl-D-erythrono-1,4-lactone is inactive alone, but elicits oviposition behavior when mixes with other fractions.		Others
TN4427	Lethedioside A		Others
	Lethedoside A was either inactive or weakly active against KB tumor cells, in contrast to previously isolated flavones from the same plant.		Others
TN3844	Didrovaltrate		Calcium Channel
	Didrovaltrate shows cytotoxic against human cancer cell lines. Didrovaltrate blocks I(Ca-L) in a concentration-dependent manner and probably inhibits I(Ca-L) in its inactive state, which may contribute to its cardiovascu...		Calcium Channel
T78499	1,5-Anhydro-D-mannitol
	1,5-Anhydro-D-mannitol, the inactive analog of 1,5-Anhydrosorbitol, serves as an experimental control, whereas 1,5-Anhydrosorbitol acts as a short-term glycemic control marker.
TN2682	2-2'-(Hydroxytetracosanoylamino)-octadecane-1,3,4-triol tetraacetate		Others
	(2S,3S,4R,2'R )-2-(2'-Hydroxytetracosanoylamino) octadecane-1,3,4-triol at concentration of 100 ug/mL shows selectively inhibitory activity against phospholipase A 2 (PLA 2) secreted from Crotalus adamenteus venom, but i...		Others
T36667	2'-Deoxyadenosine-5'-triphosphate	dATP,Deoxyadenosine 5-triphosphate	DNA/RNA Synthesis , Endogenous Metabolite
	2'-Deoxyadenosine-5'-triphosphate (Deoxyadenosine 5-triphosphate) (dATP) is a naturally occurring small molecule nucleotide used in cells for DNA synthesis or replication. 2'-Deoxyadenosine-5'-triphosphate (dATP) is a su...		DNA/RNA Synthesis , Endogenous Metabolite
TN4319	Isopimaric acid		Antifection
	Isopimaric acid is active against MDR and MRSA strains of S. aureus which are becoming increasingly resistant to antibiotics, the minimum inhibitory concentrations (MIC) are 32-64 microg/mL . Isopimaric acid is also poss...		Antifection
TN3708	Coronarin D		BCL , c-Myc , TNF , NF-κB , Caspase , COX , Antifection
	Coronarin D shows promising antifungal activity against C. albicans in vitro, the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration (MFC) were 2 and 4 mg/mL, respectively; it is active again...		BCL , c-Myc , TNF , NF-κB , Caspase , COX , Antifection

天然物製品

Hexahydrocurcumin

TQ0288

Synonym:

Target: Reactive Oxygen Species, ROS, COX

Daidzein

T1238

Synonym: Isoflavone

Target: Endogenous Metabolite, PPAR

Estrone sulfate sodium

T36857

Synonym: Estrone 3-sulfate (sodium salt),17β-Estrone 3-sulfate

Target: Endogenous Metabolite

3-Methoxytyramine hydrochloride

T4710

Synonym: 3-O-methyl Dopamine hydrochloride,3-O-methyl Dopamine hydrochloride)

Target: Others, Endogenous Metabolite, Drug Metabolite

Pregnanediol

T1688

Synonym: 5Beta-Pregnane-3Alpha,20alpha-Diol,Pregnandiol

Target: Estrogen/progestogen Receptor, Endogenous Metabolite

(-)-(S)-Equol

T6491

Synonym: (−)-Equol,Equol,4',7-Dihydroxyisoflavan,4',7-Isoflavandiol

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Endogenous Metabolite

Chloramphenicol succinate

T25240

Synonym: Paraxin succinate,Kemicetine succinate,CPSA

2-C-Methyl-D-erythrono-1,4-lactone

Target: Calcium Channel

1,5-Anhydro-D-mannitol

T78499

Synonym:

Target:

2-2'-(Hydroxytetracosanoylamino)-octadecane-1,3,4-triol tetraacetate

TN2682

Synonym:

Target: Others

2'-Deoxyadenosine-5'-triphosphate

T36667

Synonym: dATP,Deoxyadenosine 5-triphosphate

Target: DNA/RNA Synthesis, Endogenous Metabolite

Target: BCL, c-Myc, TNF, NF-κB, Caspase, COX, Antifection

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-01985	ASAH2B Protein, Human, Recombinant (His)	Human	E. coli
	N/A. ASAH2B Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 23.0 kDa and the accession number is P0C7U1.
TMPH-01733	DDAH2 Protein, Human, Recombinant (GST & His)	Human	E. coli
	Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. DDAH2 Protein, Human, Recombinant (G...
TMPH-01525	CMAHP Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell-pathogen interactions. That protein has no CMP-N-acetylneuraminate monooxygenase activity and is no...
TMPH-01226	CRMP1 Protein, Human, Recombinant	Human	E. coli
	Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance. During the axon guidance process, acts downstream of SEMA3A to promote FLNA dissociation from F...
TMPJ-00258	TGF beta 2 Protein, Human, Recombinant	Human	HEK293 Cells
	Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. T...
TMPY-02115	R-Spondin 3/RSPO3 Protein, Human, Recombinant (aa 1-146, His)	Human	HEK293 Cells
	R-spondin 3 (RSPO3) is a member of the R-Spondin (RSPO) family in vertebrates that activate Wnt/beta-catenin signaling, plays a key role in these processes. The RSPO family of secreted Wnt modulators is involved in devel...
TMPY-02078	HtrA2/Omi Protein, Human, Recombinant (His)	Human	E. coli
	Serine protease HTRA2, also known as high-temperature requirement protein A2, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI and HTRA2, is a single-pass membrane protein that belongs to the ...
TMPJ-00375	HGF Protein, Human, Recombinant (His)	Human	HEK293 Cells
	HGF, is a pleiotropic protein in the Plasminogen subfamily of S1 peptidases and contains 4 kringle domains, 1 PAN domain and 1 peptidase S1 domain. HGF is secreted as an inactive 728 amino acid (aa) single chain propepti...
TMPH-01527	NAALADL2 Protein, Human, Recombinant (His)	Human	E. coli
	May be catalytically inactive.
TMPH-00655	McjB Protein, E. coli, Recombinant (His & Myc)	E. coli	E. coli
	Along with McjC, necessary and sufficient to process the inactive microcin J25 (McjA) precursor into the active peptide.
TMPH-00293	PAG-1 Protein, Bovine, Recombinant (His)	Bovine	E. coli
	Appears to be proteolytically inactive. PAG-1 Protein, Bovine, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 40.7 kDa and the accession number is Q29432.
TMPH-00294	PAG-1 Protein, Bovine, Recombinant (His & SUMOstar)	Bovine	P. pastoris (Yeast)
	Appears to be proteolytically inactive. PAG-1 Protein, Bovine, Recombinant (His & SUMOstar) is expressed in yeast with N-6xHis-sumostar tag. The predicted molecular weight is 49.8 kDa and the accession number is Q29432.
TMPH-01736	PGLYRP2 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity. PGLYRP2 Protein, Human, Recombinant (His) is expressed in yeast w...
TMPH-00844	HSD11B2 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids. HS...
TMPH-01737	PGLYRP2 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity. PGLYRP2 Protein, Human, Recombinant (His & SUMO) is expressed in ...
TMPJ-00553	Lp-PLA2/PLA2G7 Protein, Human, Recombinant (aa 22-441, His)	Human	HEK293 Cells
	Platelet-Activating Factor Acetylhydrolase (PAFAH) is a secreted enzyme which belongs to the AB hydrolase superfamily and Lipase family and catalyzes the degradation of platelet-activating factor to biologically inactive...
TMPJ-00881	CTRB1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Chymotrypsinogen B (CTRB1) is a 263 amino acid protein with signal peptide (1-18) and Chymotrypsinogen B (19-263). Chymotrypsinogen B have three chains:Chymotrypsin B chain A(19-31), Chymotrypsin B chain B(34-164), Chymo...
TMPJ-01116	HABP2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Hyaluronan-binding protein 2（HABP2） is an extracellular serine protease which binds hyaluronic acid. It secreted as an inactive single-chain precursor and is then activated to a heterodimeric form, which consists of a 50...
TMPH-00134	AcMNPV Viral cathepsin Protein (His & SUMO)	AcMNPV	E. coli
	Cysteine protease that plays an essential role in host liquefaction to facilitate horizontal transmission of the virus. Accumulates within infected cells as an inactive proenzyme (proV-CATH), which is activated by proteo...
TMPH-00843	HSD11B1 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one ...
TMPH-00507	PGRP-SC2 Protein, Drosophila melanogaster, Recombinant (His & Myc)	Fruit fly	E. coli
	N-acetylmuramyl-L-alanine amidase involved in innate immunity by degrading bacterial peptidoglycans (PGN). Probably plays a scavenger role by digesting biologically active PGN into biologically inactive fragments. Has no...
TMPJ-01393	PGCP Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Carboxypeptidase Q (Cpq) is a member of the peptidase M28 family. PGCP is involved in a number of fundamental biological processes such as the hydrolysis of circulating peptides, catalyzing the hydrolysis of dipeptides w...
TMPJ-01229	SUMF1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Human Sulfatase Modifying Factor 1 (SUMF1) is a 42kDa protein. SUMF1 is a Ca2+-binging member of the sulfatase-modifying factor family. SUMF1 is a soluble ER lumenal glycoprotein, it converts inactive sulfatases into an ...
TMPY-00821	HGFA Protein (pro form), Human, Recombinant (His)	Human	HEK293 Cells
	HGF activator (HGFA) is a serum-derived serine protease and belongs to the peptidase family S1.HGFA is responsible for the conversion of hepatocyte growth factor (HGF), from the inactive single-chain precursor to the act...
TMPH-01041	Carboxypeptidase A6 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	May be involved in the proteolytic inactivation of enkephalins and neurotensin in some brain areas. May convert inactive angiotensin I into the biologically active angiotensin II. Releases a C-terminal amino acid, with p...
TMPH-02738	IRAK3 Protein, Mouse, Recombinant (His & Myc)	Mouse	Baculovirus Insect Cells
	Putative inactive protein kinase which regulates signaling downstream of immune receptors including IL1R and Toll-like receptors. Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by ...
TMPY-02544	FANCA Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	FANCA is one of the six known Fanconi anemia gene products (FANCA, FANCC, FANCD2, FANCE, FANCF, and FANCG proteins). Fanconi anemia (FA) is a genetic disorder predisposing to aplastic anemia and cancer characterized by h...
TMPH-01209	DENND1A Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Guanine nucleotide exchange factor (GEF) regulating clathrin-mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. Regulat...
TMPJ-00897	TPSB2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Tryptase beta-2(Tpsb2), also known as Mast cell protease 6(mMCP-6), belongs to the peptidase S1 family and Tryptase subfamily. Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled...
TMPH-02020	RGS17 Protein, Human, Recombinant (GST)	Human	E. coli
	Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2. Inhibits signal transduction by increasing the GTPase activity of G pro...
TMPH-01508	HABP2 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Cleaves the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fib...
TMPH-02334	RAB12 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bou...
TMPJ-00250	LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Transforming growth factor beta (TGFβ) family members are secreted in inactive complexes with a latency-associated peptide (LAP), a protein derived from the N-terminal region of the TGFβ gene product. Extracellular activ...
TMPJ-00815	FBPase1 Protein, Human, Recombinant (His, E. coli)	Human	E. coli
	Fructose-1,6-Bisphosphatase 1 (FBPase 1) is a member of the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory protein, which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and...
TMPJ-01001	CCL11 Protein, Human, Recombinant	Human	E. coli
	C-C Motif Chemokine 11 (CCL11) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. In response to the presence of allergens, CCL11 selectively recruits eosinophils, a prominent feature of all...
TMPH-01387	GCKR Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Regulates glucokinase (GCK) by forming an inactive complex with this enzyme. Acts by promoting GCK recruitment to the nucleus, possibly to provide a reserve of GCK that can be quickly released in the cytoplasm after a me...
TMPH-01388	GCKR Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Regulates glucokinase (GCK) by forming an inactive complex with this enzyme. Acts by promoting GCK recruitment to the nucleus, possibly to provide a reserve of GCK that can be quickly released in the cytoplasm after a me...
TMPJ-00962	AKR1C3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	AKR1C3, is an enzyme which belongs to the aldo/keto reductase family. It is expressed in many tissues including adrenal gland, brain, kidney, liver, lung, mammary gland, placenta, small intestine, colon, spleen, prostate...
TMPJ-01225	PDILT Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Protein Disulfide-Isomerase-Like Protein of the Testis (PDILT) is a protein that belongs to the protein disulfide isomerase family. Human PDILT is synthesized as a 584 amino acid precursor that contains an 20 amino acid ...
TMPY-02965	MMP-19 Protein, Human, Recombinant	Human	E. coli
	MMP19, also known as RASI-1, is a member of the peptidase M1A family. It contains 4 hemopexin-like domains and is expressed in the mammary gland, placenta, lung, pancreas, ovary, small intestine, spleen, thymus, prostate...
TMPJ-00869	GLB1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	β Galactosidase is a lysosomal β Galactosidase that hydrolyzes the terminal β Galactose from Ganglioside and Keratan sulfate. In lysosome, the mature β Galactosidase protein associates with Cathepsin A and Neuraminidase ...
TMPJ-01292	Chemerin/RARRES2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Retinoic acid receptor responder protein 2(RARRES2) is a secreted protein that in humans is encoded by the RARRES2 gene. It is highly expressed in skin, also found in pancreas, liver, spleen, prostate, ovary, small intes...
TMPJ-00474	CPA1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Carboxypeptidase A1 (CPA1) is secreted as a pancreatic peptidase that comes from the precursor form of inactive procarboxypeptidase. CPA1 comprises a signal peptide, a pro region and a mature chain, and can be activated ...
TMPY-03747	Fucose Mutarotase Protein, Human, Recombinant (His)	Human	E. coli
	FUOM, also known as fucose mutarotase and FucM, belongs to the RbsD / FucU family. FUOM is involved in the interconversion between alpha- and beta-L-fucoses. L-Fucose has two isforms: alpha-L-fucose (29.5%) and beta-L-fu...
TMPY-01580	PRSS2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Trypsin-2, also known as Trypsin II, Anionic trypsinogen, Serine protease 2, PRSS2 and TRY2, is a secreted protein that belongs to the trypsin serine protease family including Trypsin, PRSS1, PRSS2 and PRSS3. It consists...
TMPY-03608	EEF1B2 Protein, Human, Recombinant (His)	Human	E. coli
	EF1B, also known as EEF1B2, is a translation elongation factor. It belongs to the EF-1-beta/EF-1-delta family. Elongation factors are a set of proteins that are used in protein synthesis in the cell. In the ribosome, the...
TMPY-02847	Moesin Protein, Human, Recombinant (aa 1-346, His)	Human	E. coli
	Moesin is a member of the ERM family which includes ezrin and radixin. ERM proteins, highly related members of the larger protein 4.1 superfamily, can exist in an active or inactive conformation. It seems that ERM protei...
TMPJ-00554	Vinculin Protein, Human, Recombinant	Human	E. coli
	Vinculin is a focal adhesion and cytoskeletal protein that distributed mainly at cell-cell junctions and cell-extracellular matrix (ECM) adhesion that belongs to the Vinculin/α-Catenin family. Vinculin is an Actin-bindin...
TMPJ-01064	Serpin G1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	SERPIN G1 is a member of the serpin family, The C-terminal serpin domain is similar to other serpins, and this part of C1-INH provides the inhibitory activity. SERPIN G1 is involved in the inhibition of the complement sy...
TMPY-04546	CLK3 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	Dual specificity protein kinase CLK3, also known as CDC-like kinase 3, and CLK3, is a member of CMGC Ser/Thr protein kinase family and Lammer subfamily. Mammalian CLK is the prototype for a family of dual specificity ...
------------------------ More ------------------------