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天然化合物

249

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同位体標識化合物

カタログ番号	製品名	別名	ターゲット
T9750	Cetyldimethylethylammonium Bromide		Others
	Cetyldimethylethylammonium Bromide can be used to induce extracellular secretion of beta-galactosidase.		Others
T0234	Methicillin sodium salt	Methicillin sodium,Meticillin sodium	Antibacterial , Antibiotic
	Methicillin sodium salt is the sodium salt form of methicillin, a semisynthetic beta-lactam penicillin antibiotic with beta-lactamase resistant activity.		Antibacterial , Antibiotic
T18894	5(6)-CFDA	CFDA,5-(6)-Carboxyfluorescein diacetate	Others
	5(6)-CFDA (5-(6)-Carboxyfluorescein diacetate) is a cell-permeant esterase substrate that can serve as a viability probe that measures both enzymatic activities, which is required to activate its fluorescence, and cell-m...		Others
T1418	Bucladesine sodium	dbcAMP,Dibutyryl-cAMP sodium salt,Dibutyryl-cAMP,DC2797,Sodium dibutyryl cAMP,Bucladesine,Bucladesine sodium salt	PKA , PDE
	Bucladesine sodium (DC2797) is a cAMP analog with cell-permeable properties. Bucladesine sodium is also a cAMP-dependent protein kinase (PKA) activator and a phosphodiester (PDE) inhibitor. Bucladesine sodium has anti-in...		PKA , PDE
T19783	Dehydroabiethylamine	NSC-2955,NSC 2955,Dehydroabietylamine,NSC2955,Leelamine free base,Leelamine	P450 , PDK
	Dehydroabiethylamine (NSC-2955) is an inducer of hepatic CYP2B activity. Dehydroabiethylamine inhibits pyruvate dehydrogenase kinases (PDKs) and intracellular cholesterol transport with anti-tumor activity.		P450 , PDK
T73599	TSPO ligand-1		Autophagy
	TSPO ligand-1 has affinity for peripheral and central benzodiazepine receptors.TSPO ligand-1 is an AUTAC4-binding protein in the transmembrane domain of the outer mitochondrial membrane, which induces mitochondrial autop...		Autophagy
T10222	ABMA		Parasite
	ABMA is a broad-spectrum inhibitor of intracellular toxins and pathogens. ABMA efficiently protects cells against various pathogens including viruses, intracellular bacteria, and parasite. ABMA selectively acts at host c...		Parasite
T12204	NecroX-5		Calcium Channel
	NecroX-5, a derivative of NecroX, exhibits anti-inflammatory and anti-cancer activities. NecroX-5 reduces intracellular calcium concentration.		Calcium Channel
T3543	NS-638	NS 638	Calcium Channel
	NS-638 is a Ca2+-channel blocker. It can block K+-stimulated intracellular Ca2+-elevation (IC50: 3.4 μM).		Calcium Channel
T35351L	GO-203 acetate	GO-203 acetate (1222186-26-6 Free base)	Others
	GO-203 acetate is an effective inhibitor of potent MUC1-C oncoprotein. GO-203 acetate exhibits anti-cancer activities targeting intracellular proteins.		Others
T10247	Adenosine 5'-diphosphoribose sodium	Adenosine 5'-diphosphoribose sodium,ADP ribose sodium	Endogenous Metabolite , TRP/TRPV Channel , Autophagy
			Endogenous Metabolite , TRP/TRPV Channel , Autophagy
T4278	AM966		LPA Receptor , LPL Receptor
	AM966, a excellent affinity, specific, oral LPA1(IC50=17 nM) antagonist, suppresses LPA-stimulated intracellular calcium release.		LPA Receptor , LPL Receptor
T38851	SiR-COOH
	SiR-COOH enables tracking of the model therapeutic drug's intracellular location in GFP cells, characterized by absorption (Abs) at 645 nm and emission (Em) at 676 nm.
T5426	DMNQ		Reactive Oxygen Species , ROS
	DMNQ is a 1,4-naphthoquinone that acts as a redox-cycling agent, typically increasing intracellular superoxide and hydrogen peroxide formation.DMNQ increases ROS generation		Reactive Oxygen Species , ROS
T2535	Ivabradine hydrochloride	S 16257-2,Ivabradine HCl	Adrenergic Receptor
	Ivabradine hydrochloride (S 16257-2) is a new If inhibitor (IC50: 2.9 μM). Ivabradine Hydrochloride is the hydrochloride salt form of ivabradine, an orally bioavailable, hyperpolarization-activated, cyclic nucleotide-gat...		Adrenergic Receptor
T2010	S0859		Others
	S0859 is an N-cyanosulphonamide that blocks the sodium/bicarbonate cotransporter (NBC, also known as SLC4A7), which regulates intracellular pH.		Others
T24836	ß-pBrPh-Glc	Beta-pBrPh-Glc,ßpBrPhGlc,p-Bromophenyl-beta-D-glucopyranoside,p-Bromophenyl-ß-D-glucopyranoside	Antioxidant
	ß-pBrPh-Glc (ßpBrPhGlc) is an inhibitor of ice recrystallization, controlling the growth of extracellular ice and inhibiting the recrystallization of intracellular ice. ß-pBrPh-Glc may be used as a cryopreservative , pos...		Antioxidant
T14566	BI-9627		Sodium Channel
	BI-9627 is a selective and potent sodium hydrogen exchange isomer 1 (NHE1) inhibitor.BI-9627 partially reverses the effects of DMA with IC50 values of 6 and 31 nM in the intracellular pH recovery (pHi) and human platelet...		Sodium Channel
T12470	Picloxydine		Antibacterial
	Picloxydine is a heterocyclic biguanide with antiplaque and antibacterial activity.		Antibacterial
T12201	Nebracetam hydrochloride	WEB 1881 FU hydrochloride	AChR
	Nebracetam hydrochloride (WEB 1881 FU hydrochloride) is an agonist nootropic M1-muscarinic. Nebracetam hydrochloride induces a rise of intracellular Ca2+ concentration. Nebracetam hydrochloride exhibits an EC50 of 1.59 m...		AChR
T16111	ML604086		CCR
	ML604086 suppresses CCL1 mediated chemotaxis and enhances intracellular Ca2 concentrations. ML604086 is a selective inhibitor of CCR8. It also inhibiting CCL1 binding to CCR8 on circulating T-cells.		CCR
TP2319	Thymosin β4 acetate(75591-33-4 free base)		Autophagy
	Thymosin β4 (Tβ4) is a thymic hormone with multiple and different intracellular and extracellular activities affecting wound healing, inflammation, fibrosis and tissue regeneration.		Autophagy
T1416	Zidovudine	Azidothymidine,NSC 602670,ZDV,AZT	HIV Protease , Reverse Transcriptase , Telomerase , CRISPR/Cas9
	Zidovudine (ZDV) is a synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the inhibition of DNA replication and cell death. This age...
T14057	6-CFDA	6-Carboxyfluorescein diacetate	Others
	6-CFDA (6-Carboxyfluorescein diacetate) is fluorescent polyanionic probe that used to measure changes in intracellular pH (pHi) and processes such as dendrimer aggregation and absorption.		Others
T8984	FLTX1		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
	FLTX1 is a fluorescent derivative of Tamoxifen, designed to efficiently target and label intracellular Tamoxifen-binding sites (estrogen receptors) both under permeabilized and non-permeabilized conditions. Additionally,...		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
T15458	H2DCFDA	2',7'-Dichlorodihydrofluorescein diacetate,DCFH-DA	Reactive Oxygen Species
	H2DCFDA (DCFH-DA) belongs to the class of green fluorescent dyes and is a probe for the detection of intracellular reactive oxygen species (ROS) (Ex/Em=488/525 nm) with cell membrane permeability.		Reactive Oxygen Species
T27710	K6PC-5	K6PC5,K6PC 5	S1P Receptor
	K6PC-5 is a ceramide derivative that acts as an activator of sphingosine kinase 1 (SPHK1), inducing a swift and temporary rise in intracellular calcium levels. With its potential applications in skin diseases associated ...		S1P Receptor
T21876	DC_AC50		Apoptosis , Others
	DC_AC50 is a dual inhibitor of Atox1 and CCS (copper chaperones). Inhibiting intracellular copper chaperones as a means of reducing/preventing acquired chemotherapy resistance.DC_AC50 binding to Atox1 and CCS and reducin...		Apoptosis , Others
T37428	TRPC6-PAM-C20	TRPC6-PAM-C20,3-(6,7-Dimethoxy-3,3-dimethyl-3,4-dihydro-isoquinolin-1-yl)-chromen-2-one	TRP/TRPV Channel
	TRPC6-PAM-C20 is a selective TRPC6 positive allosteric modulator. TRPC6-PAM-C20 induces transient increase in intracellular Ca2+ in HEK cells expressing TRPC6 with an EC50 of 2.37 μM. TRPC6-PAM-C20 enhances OAG-induced p...		TRP/TRPV Channel
T14569	BI8626		E1/E2/E3 Enzyme
	BI8626 is a ubiquitin ligase HUWE1 inhibitor with protective effects against spontaneous desiccation syndrome in NOD/ShiLtj mice.BI8626 inhibits intracellular cholesterol and decreases the expression of phosphorylated ZA...		E1/E2/E3 Enzyme
T8320	J14	J-14	Reactive Oxygen Species
	J-14 is an inhibitor of reversible sulfiredoxin(IC50 : 8.1 μM). J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin, leading to cytotoxicity and cancer cell death		Reactive Oxygen Species
T1713	IBMX	3-Isobutyl-1-methylxanthine,1-Methyl-3-Isobutylxanthine,Methylisobutylxanthine,Isobutylmethylxanthine	PDE
	IBMX (Methylisobutylxanthine) is a broad-spectrum phosphodiesterase (PDE) inhibitor with inhibitory activity against PDE3, PDE4, and PDE5 (IC50=6.5/26.3/31.7 μM). IBMX enhances the intracellular cAMP level.		PDE
T15049	Daltroban	BM-13505,SKF 96148	PPAR
	Daltroban (SKF 96148) is a specific thromboxane A2 (TXA2) receptor antagonist. Daltroban shows protective effect in reperfusion injury. Daltroban increase intracellular calcium in vascular smooth muscle cells.		PPAR
T27061	CP-24879 hydrochloride	CP-24879 HCl	Others
	CP-24879 hydrochloride (CP-24879 HCl), a Δ5D/Δ6D dual-inhibitor, can significantly reduce intracellular lipid accumulation and inflammatory injury in hepatocytes. CP-24879 hydrochloride exhibits superior antisteatotic an...		Others
T13320	VU591 hydrochloride		Potassium Channel
	VU591 hydrochloride is a selective renal outer medullary potassium channel (Kir1.1, ROMK) antagonist (IC50：0.24 μM). Thought to block the intracellular pore of the Kir1.1 channel. Exhibits no effect on Kir7.1 at concentr...		Potassium Channel
T13219	TTA-Q6		Calcium Channel
	TTA-Q6 is a selective T-type Ca2+ channel antagonist with potential antitumor and immunomodulatory activity for the treatment of neurological disorders by inhibiting the uptake of extracellular calcium ions by tumor cell...		Calcium Channel
T17028	Tefinostat	CHR-2845	HDAC
	Tefinostat (CHR-2845) is a potent monocyte/macrophage-targeted histone deacetylase (HDAC) inhibitor. Tefinostat is cleaved to the active acid CHR-2847 by the intracellular esterase human carboxylesterase-1 (hCE-1).Tefino...		HDAC
T64755	Ammonium Chloride		Autophagy , Antifungal
	Ammonium chloride acts as a small molecule autophagy inhibitor.Ammonium chloride is a pH-regulating, heteropolar compound that can cause intracellular alkalosis and metabolic acidosis, thereby affecting enzyme activity a...		Autophagy , Antifungal
T31931L	Gizzerosine HCl	Gizzerosine HCl(89238-78-8 Free base)	Others
	Gizzerosine 2HCl, a substance produced during the heat treatment of fishmeal, induces histopathological lesions in broiler chicks and increases intracellular cyclic adenosine-3',5'-monophosphate levels in isolated chicke...		Others
T14048	5-CFDA	5-Carboxyfluorescein diacetate	Others
	5-CFDA (5-Carboxyfluorescein diacetate)(5-Carboxyfluorescein diacetate) is membrane-permeant. It can be loaded into cells via incubation and hydrolyzed by intracellular esterases to 5-carboxyfluorescein that is used for ...		Others
T19033	Nile Red	Phenoxazone 9,Nile Blue A oxazone	Others
	Nile Red (Nile Blue A oxazone) is a strongly fluorescent stain used for the detection of intracellular lipid droplets in the presence of a hydrophobic environment.		Others
T2213	Terconazole	Gyno-Terazol,Terazol 3,Terazol 7,Triaconazole,R42470	Antifection , Antifungal
	Terconazole (Terazol 7) is a synthetic triazole derivative structurally related to fluconazole, antifungal Terconazole seems to disrupt cell wall synthesis by inhibiting biosynthesis of ergosterol or other sterols, damag...		Antifection , Antifungal
T17250	W-54011		ROS , Complement System
	W-54011 is a potent non-peptide C5a receptor antagonist. W-54011 inhibits the binding of 125I-labeled C5a to human neutrophils (Ki: 2.2 nM). W-54011 inhibits C5a-induced intracellular Ca2+ mobilization, chemotaxis, and g...		ROS , Complement System
T0289	9-Aminoacridine	Aminacrine	Others , HIV Protease , Antibacterial
	9-Aminoacridine is a highly fluorescent anti-infective dye used clinically as a topical antiseptic and experimentally as a mutagen, due to its interaction with DNA. It is also used as an intracellular pH indicator.		Others , HIV Protease , Antibacterial
T36488	LYG-202	LYG202,LYG 202	Apoptosis , ROS
	LYG-202 is a novel flavonoid with piperazine substitution and antitumor effects in vivo and in vitro.LYG-202 induced apoptosis in MCF-7, MDA-MB-231, and MDA-MB-435 cells, and increased intracellular ROS production.		Apoptosis , ROS
T77762	ROS-generating agent 1		Apoptosis , Ferroptosis , ROS Kinase
	Ros-generating agent 1 has anticancer activity and generates ROS by covalently modifying Sec-498 residues of TrxR. ROS-generating agent 1 reduces intracellular TrxR protein levels and promotes ROs-dependent apoptosis and...		Apoptosis , Ferroptosis , ROS Kinase
T41008	BODIPY-Cholesterol	BCh2
	BODIPY-Cholesterol (TF-Chol) is a cholesterol analog with a fluorescent BODIPY motif and cellular permeability, and is a novel BODIPY cholesterol probe.BODIPY-Cholesterol can be used to study intracellular sterol uptake ...
T9518	Inarigivir ammonium	ORI-9020 ammonium,SB-9200 ammonium	HBV
	Inarigivir ammonium (SB-9200 ammonium) is a dinucleotide antiviral compound that significantly reduces HBV DNA in transgenic mice expressing hepatitis B virus. Inarigivir is an agonist of retinoic acid-inducible gene-I (...		HBV
T22967	MEDICA16	MEDICA 16	GPR , Others , ATP Citrate Lyase
	Free fatty acid 1 (FFA1/GPR40) receptor agonist		GPR , Others , ATP Citrate Lyase
T20067	WST-1	WST 1
	WST-1 is a cytotoxic, water-soluble tetrazolium salt that induces intracellular mitochondrial dehydrogenases to undergo NADH-dependent enzymatic reactions, releasing water-soluble methylbenzene products.WST-1 can be used...

Compounds

Cetyldimethylethylammonium Bromide

T9750

Synonym:

Target: Others

Methicillin sodium salt

T0234

Synonym: Methicillin sodium,Meticillin sodium

Target: Antibacterial, Antibiotic

5(6)-CFDA

T18894

Synonym: CFDA,5-(6)-Carboxyfluorescein diacetate

Target: Others

Bucladesine sodium

T1418

Synonym: dbcAMP,Dibutyryl-cAMP sodium salt,Dibutyryl-cAMP,DC2797,Sodium dibutyryl cAMP,Bucladesine,Bucladesine sodium salt

Target: PKA, PDE

Dehydroabiethylamine

T19783

Synonym: NSC-2955,NSC 2955,Dehydroabietylamine,NSC2955,Leelamine free base,Leelamine

Target: Calcium Channel

NS-638

T3543

Synonym: NS 638

Target: Calcium Channel

GO-203 acetate

T35351L

Synonym: GO-203 acetate (1222186-26-6 Free base)

Target: Others

Adenosine 5'-diphosphoribose sodium

T10247

Synonym: Adenosine 5'-diphosphoribose sodium,ADP ribose sodium

Target: Endogenous Metabolite, TRP/TRPV Channel, Autophagy

AM966

T4278

Synonym:

Target: LPA Receptor, LPL Receptor

Target: Reactive Oxygen Species, ROS

Ivabradine hydrochloride

T2535

Synonym: S 16257-2,Ivabradine HCl

Target: Adrenergic Receptor

Synonym: Beta-pBrPh-Glc,ßpBrPhGlc,p-Bromophenyl-beta-D-glucopyranoside,p-Bromophenyl-ß-D-glucopyranoside

Target: Sodium Channel

Picloxydine

T12470

Synonym:

Target: Antibacterial

Nebracetam hydrochloride

T12201

Synonym: WEB 1881 FU hydrochloride

Thymosin β4 acetate(75591-33-4 free base)

Synonym: Azidothymidine,NSC 602670,ZDV,AZT

Target: HIV Protease, Reverse Transcriptase, Telomerase, CRISPR/Cas9

6-CFDA

T14057

Synonym: 6-Carboxyfluorescein diacetate

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

H2DCFDA

T15458

Synonym: 2',7'-Dichlorodihydrofluorescein diacetate,DCFH-DA

Target: Reactive Oxygen Species

K6PC-5

T27710

Synonym: K6PC5,K6PC 5

Target: Apoptosis, Others

TRPC6-PAM-C20

T37428

Synonym: TRPC6-PAM-C20,3-(6,7-Dimethoxy-3,3-dimethyl-3,4-dihydro-isoquinolin-1-yl)-chromen-2-one

Target: TRP/TRPV Channel

BI8626

T14569

Synonym:

Target: E1/E2/E3 Enzyme

J14

T8320

Synonym: J-14

Target: Reactive Oxygen Species

IBMX

T1713

Synonym: 3-Isobutyl-1-methylxanthine,1-Methyl-3-Isobutylxanthine,Methylisobutylxanthine,Isobutylmethylxanthine

Target: PDE

Daltroban

T15049

Synonym: BM-13505,SKF 96148

Target: PPAR

CP-24879 hydrochloride

T27061

Synonym: CP-24879 HCl

Target: Potassium Channel

TTA-Q6

T13219

Synonym:

Target: Calcium Channel

Target: Autophagy, Antifungal

Gizzerosine HCl

T31931L

Synonym: Gizzerosine HCl(89238-78-8 Free base)

Target: Others

5-CFDA

T14048

Synonym: 5-Carboxyfluorescein diacetate

Target: Others

Nile Red

T19033

Synonym: Phenoxazone 9,Nile Blue A oxazone

Target: Others

Terconazole

T2213

Synonym: Gyno-Terazol,Terazol 3,Terazol 7,Triaconazole,R42470

Target: Antifection, Antifungal

W-54011

T17250

Synonym:

Target: ROS, Complement System

9-Aminoacridine

T0289

Synonym: Aminacrine

Target: Others, HIV Protease, Antibacterial

LYG-202

T36488

Synonym: LYG202,LYG 202

Target: Apoptosis, ROS

ROS-generating agent 1

T77762

Synonym:

Target: Apoptosis, Ferroptosis, ROS Kinase

Synonym: ORI-9020 ammonium,SB-9200 ammonium

Target: GPR, Others, ATP Citrate Lyase

カタログ番号	製品名	別名	ターゲット
T31467	Dihydrocyclosporin A	Dihydrocyclosporin-A	Others
	Dihydrocyclosporin A (Dihydrocyclosporin-A) is closely related co-metabolite of cyclosporin A. Dihydrocyclosporin A significantly inhibits promastigotes and intracellular amastigotes.		Others
T19122	3-Methylvaleric Acid		Others , Endogenous Metabolite
	3-Methylvaleric Acid is an edible grade flavor present in tobacco.3-Methylvaleric Acid enhances intracellular cAMP accumulation and CRE-luciferase activity in CHO-K1 cells and HEK293 cells.		Others , Endogenous Metabolite
T0421	I-Inositol	Inositol,myo-Inositol,meso-Inositol	Endogenous Metabolite
	i-Inositol (myo-Inositol) is a intracellular phosphate compound, involved in cell signaling and may stimulate tumor cell differentiation.		Endogenous Metabolite
T7924	8-Bromoguanosine		Others
	8-Bromoguanosine is a brominated derivative of guanosine. It is activate lymphocytes through an intracellular mechanism to exert immunostimulatory effects.		Others
T3093	Spermine tetrahydrochloride	Spermine Tetrahydrochloride,Neuridine tetrahydrochloride,Musculamine tetrahydrochloride,Gerontine tetrahydrochloride	Others , Endogenous Metabolite
	Spermine tetrahydrochloride (Musculamine tetrahydrochloride) is a polyamine involved in cellular metabolism found in all eukaryotic cells. It is a major natural intracellular compound capable of protecting DNA from free ...		Others , Endogenous Metabolite
TN1425	Bacoside A3		ATPase , ROS , P-gp
	Bacoside A3 has antioxidant potential, it shows comparatively higher neuroprotective response analysed as higher cell viability and decreased intracellular ROS.		ATPase , ROS , P-gp
TN1480	Cephaeline		Virus Protease , Influenza Virus , HIF
	Cephaeline was highly active against protected primary CLL cells (relative IC50's 35nM ) and acted by repressing HIF-1α± and disturbing intracellular redox homeostasis.		Virus Protease , Influenza Virus , HIF
T0146	Tioconazole	UK-20349,Vagistat	Antibiotic , Antifection , Antifungal
	Tioconazole (Vagistat) is a synthetic imidazole derivative, inhibits cell wall synthesis by inhibiting the biosynthesis of ergosterol or other sterols, damaging the fungal cell membrane, altering its permeability, and pr...		Antibiotic , Antifection , Antifungal
T3220	Euphorbiasteroid	Euphobiasteroid,Euphorbia factor L1	Others , AMPK
	Euphorbiasteroid (Euphobiasteroid) (25-50 μM) decreased differentiation of 3T3-L1 cells via reduction of intracellular triglyceride (TG) accumulation.		Others , AMPK
T20819	Ammonium iron(III) citrate	Ferric ammonium citrate	Others , Ferroptosis
	Ammonium iron(III) citrate (Ferric ammonium citrate) is a physiological form of non-ferritin-bound iron that causes intracellular iron overload leading to cellular iron death and enhances protein production.		Others , Ferroptosis
T2812	ATP disodium salt hydrate	ATP disodium,ATP disodium salt,Adenosine disodium triphosphate	Others , Endogenous Metabolite
	ATP disodium salt hydrate (Adenosine disodium triphosphate) is a nucleoside triphosphate used in cells as a coenzyme often called the "molecular unit of currency" of intracellular energy transfer.		Others , Endogenous Metabolite
T4922	Uridine 5′-triphosphate tris salt	Uridine 5'-triphosphoric acid	Others , Endogenous Metabolite
	Uridine 5′-triphosphate tris salt (Uridine 5'-triphosphoric acid) is an agonist to the P2Y receptor and has been used to study concentrations of intracellular Ca2+, as well as a phosphate donor for in vitro kinase assays...		Others , Endogenous Metabolite
TQ0298	Fagomine	D-Fagomine	ROS , glycosidase
			ROS , glycosidase
T3S2296	Gardenoside		Others
	Gardenoside has hepatoprotective, pain‑relieving, and anti-mastitis effects. it may be a potential therapeutic herb against NASH by suppressed supernatant inflammatory cytokine production and intracellular NFkB act...		Others
T19676	Tributyrin	NSC661583,NSC 661583,NSC-661583	Apoptosis
	Tributyrin (Glyceryl tributyrate), a neutral short-chain fatty acid triglyceride, is a stable and rapidly absorbed prodrug of Butyric Acid. Tributyrin diffuses through biological membranes and is metabolized by intracell...		Apoptosis
T40179	Sodium Camptothecin		DNA/RNA Synthesis
	Sodium Camptothecin is a plant alkaloid with antitumor activity. Sodium Camptothecin is a reversible RNA synthesis inhibitor. Sodium Camptothecin is an effective adenovirus replication inhibitor. Sodium Camptothecin i...		DNA/RNA Synthesis
T75636	(E/Z)-Squalene	(E/Z)-Super Squalene,(E/Z)-AddaVax
	(E/Z)-Squalene ((E/Z)-AddaVax) regulates intracellular reactive oxidant species (ROS) production and induces apoptosis and necrosis in a concentration and time-dependent manner. (E/Z)-Squalene accumulates in the liver an...
T4A2462	Telocinobufagin	Telobufotoxin,Telocinobufogenin	Others
	1. Telocinobufagin (Telobufotoxin) is the major endogenous digitalis-like factor. 2. Telocinobufagin significantly decreases the bacterial burdens in the spleen and prolongs the survival time of FIST-immunized mice chall...		Others
T5120	Rhamnose	6-Deoxyhexopyranose,6-Deoxy-L-mannose,alpha-L-Rhamnose	Calcium Channel , Endogenous Metabolite
	Addition of the Rhamnose (6-Deoxy-L-mannose)-rich polysaccharide, RROP-1, to normal human dermal fibroblasts (NHDFs) and human endothelial cells produced a dose-dependent stimulation of the calcium-signaling pathway, ind...		Calcium Channel , Endogenous Metabolite
TN1065	Hirsutine		Apoptosis
	Hirsutine induces apoptosis and is a potent Dengue virus inhibitor exhibiting low cytotoxicity.Hirsutine has anticancer, cardioprotective, anti-hypertensive and anti-arrhythmic activities, it also has vasodilatation acti...		Apoptosis
T20089	ATP	Atipi,ATP disodium salt hydrate,Triphosphoric acid adenosine ester,Ara-ATP,Triphosphaden,Adenosine triphosphate;Ara-ATP,Adenosine triphosphate	Endogenous Metabolite
	ATP (Adenosine triphosphate) provides cellular energy, participates in overall energy balance, and maintains intracellular homeostasis. ATP can act as an extracellular signaling molecule through interactions with specifi...		Endogenous Metabolite
T70955	Vinaxanthone	SM-345431	Phospholipase , Antibacterial
	Vinaxanthone (SM-345431) is a small molecule compound derived from Penicillium chrysogenum that is a selective and potent semaphorin3A, phospholipase C (PLC), and FabI inhibitor, inhibiting semaphorin3A and FabI.Vinaxant...		Phospholipase , Antibacterial
T8183	Deslanoside	Desacetyllanatoside C,Deacetyllanatoside C	ATPase , Drug Metabolite
	Deslanoside (Desacetyllanatoside C) is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms. Deslanoside inhibits the Na-K-ATPase membrane p...		ATPase , Drug Metabolite
TN7225	2'-Hydroxy-3,4-dimethoxychalcone		Antioxidant , Parasite
	2'-Hydroxy-3,4-dimethoxychalcone, a chalcone compound isolated from the roots of Sophora japonica, has antioxidant activity and inhibited the intracellular survival of Lactobacillus donovani Parasite EC.50 Values ranged ...		Antioxidant , Parasite
T4973	Paraxanthine	1,7-DIMETHYLXANTHINE	Endogenous Metabolite
	Paraxanthine (1,7-dimethylxanthine) is a metabolite of caffeine (sc-202514) which functions as an adenosine receptor ligand and a PARP-1 inhibitor in pulmonary epithelial cells. Studies suggest that Paraxanthine is struc...		Endogenous Metabolite
T3S1701	Dihydrocurcumin		PPAR , Fatty Acid Synthase
	Dihydrocurcumin is the main metabolite of curcumin, which can reduce fat accumulation and oxidative stress response. Dihydrocurcumin can regulate the mRNA and protein expression levels of SREBP-1C, PNPLA3 and PPARα, incr...		PPAR , Fatty Acid Synthase
T21500	Sphingosine-1-phosphate	S1P	Endogenous Metabolite , S1P Receptor , LPL Receptor
	Sphingosine-1-phosphate (S1P) is an agonist for S1P1-5 receptors and a ligand for GPR3, GPR6, GPR12.Sphingosine-1-phosphate is an intracellular second messenger that mobilises Ca2+ as an extracellular ligand for G-protei...		Endogenous Metabolite , S1P Receptor , LPL Receptor
T7285	Ionomycin		Calcium Channel
	Ionomycin is an calcium ionophore and an antibiotic that binds calcium ions (Ca2+). It is produced by the bacterium Streptomyces conglobatus.It is used in research to raise the intracellular calcium level (Ca2+) and as ...		Calcium Channel
T0892	Diphylline	Dyphylline,Diprophylline	PDE , Adenosine Receptor
	Diphylline (Diprophylline) is a xanthine derivative. Diphylline exerts bronchodilator effects and to a lesser extent vasodilator and diuretic properties. Diphylline probably acts as a competitive inhibitor of phosphodies...		PDE , Adenosine Receptor
TJS0387	Desoxyrhaponticin	Deoxyrhapontin,Deoxyrhaponticin	Apoptosis , Fatty Acid Synthase
	1. Desoxyrhaponticin (Deoxyrhaponticin) is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes, the in vivo antidiabetic action of this compound can be explained, in part at least...		Apoptosis , Fatty Acid Synthase
T5S1097	Neferine	(R)-1,2-Dimethoxyaporphine,(-)-Neferine	Apoptosis , NF-κB , Autophagy
	1. Neferine ((-)-Neferine) has anti-tumor activities , Metabolic activation mediated by CYP3A4 and GSH depletion enhanced Neferine-induced cytotoxicity. 2. Neferine can be helpful to increase the efficacy of DOX and to a...		Apoptosis , NF-κB , Autophagy
T4969	Guanosine 5'-triphosphate trisodium salt	GTP Trisodium salt,5'-GTP trisodium salt	Endogenous Metabolite
	Guanosine 5'-triphosphate trisodium salt (5'-GTP trisodium salt) activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of se...		Endogenous Metabolite
T2836	Isorhamnetin	3-methylquercetin,3'-Methylquercetin,Isorhamnetol,3'-Methoxyquercetin	MEK , PI3K , Endogenous Metabolite
	Isorhamnetin (3-methylquercetin) is the methylated metabolite of quercetin. Quercetin is an important dietary flavonoid with in vitro antioxidant activity. Isorhamnetin prevents endothelial cell injuries from oxidized LD...		MEK , PI3K , Endogenous Metabolite
T4518	Licochalcone D		ERK , NF-κB
	Licochalcone D may be a potential drug for human melanoma treatment by inhibiting proliferation, inducing apoptosis via the mitochondrial pathway and blocking cell migration and invasion. Licochalcone D has cardioprotect...		ERK , NF-κB
T6S0721	Orientin	Lutexin,Luteolin-8-glucoside	Others
	1. Orientin (Luteolin-8-glucoside) may be regarded as a candidate therapeutic agent for treatment of vascular inflammatory diseases via inhibition of the HMGB1 signaling pathway. 2. Orientin protects vascular barrier int...		Others
T3229	Cytochalasin D		ATPase , p38 MAPK , Calcium Channel , Akt , PI3K
	Cytochalasin D is an actin inhibitor, the removal of actin stress fibers is crucial for the chondrogenic differentiation. It may be an inhibitor of some fertilization processes such as sperm penetration or sperm head dec...		ATPase , p38 MAPK , Calcium Channel , Akt , PI3K
T4918	DL-Glyceraldehyde	Glyceric aldehyde	Reductase
	DL-Glyceraldehyde (Glyceric aldehyde) is produced from the action of the enzyme glyceraldehyde dehydrogenase, which converts glycerol to glyceraldehyde using NADP as a cofactor. When present at sufficiently high levels, ...		Reductase
T6S0525	Farrerol		ERK , p38 MAPK , Akt
	1. Farrerol has antioxidative activity.2. Farrerol modulates TAP and BNBD5 gene expression in mammary gland, enhances bMEC defense against S. aureus infection and could be useful in protection against bovine mastitis. 3....		ERK , p38 MAPK , Akt
T5S1632	Barlerin	8-O-Acetylshanzhiside methyl ester,ND01	VEGFR , TNF , NF-κB , Akt , Caspase
	Barlerin (8-O-Acetylshanzhiside methyl ester) has potential against cerebral ischemic injury, and its protective effect on oxygen-glucose deprivation-induced injury might be due to the suppression of intracellular Ca2+ e...		VEGFR , TNF , NF-κB , Akt , Caspase
T4S2326	Cornuside	7-Galloylsecologanol,7-O-Galloylsecologanol,Comuside	ERK , p38 MAPK , NF-κB , JNK
	1. Cornuside (Comuside) has immunomodulatory activity . 2. Cornuside suppresses expression levels of cytokine-induced proinflammatory and adhesion molecules in the human endothelial cells. 3. Cornuside can treat myocardi...		ERK , p38 MAPK , NF-κB , JNK
T37974	(S)-Coriolic acid	13(S)-HODE	Lipoxygenase , Mitochondrial Metabolism , PPAR
	(S)-Coriolic acid (13(S)-HODE) is an important intracellular signaling agent, generated by the reaction of linoleic acid with plant and mammalian lipoxygenases, and is involved in cell proliferation and differentiation i...		Lipoxygenase , Mitochondrial Metabolism , PPAR
T37280	PE(18:1(9Z)/0:0)		Endogenous Metabolite
	PE(18:1(9Z)/0:0) is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine. PE(18:1(9Z)/0:0) induces transient increases in intracellular calcium in PC12 rat neuronal cells in a ...		Endogenous Metabolite
TN1241	3,8''-Biapigenin	3,8'-Biapigenin	ROS
	3, 8''-Biapigenin can modulate intracellular ROS production.		ROS
TN4073	Forskolin G		Others
	Forskolin is known to elevate intracellular cAMP levels.		Others
TN2543	1β-Hydroxyeuscaphic acid	1beta-Hydroxyeuscaphic acid	Others
	1beta-Hydroxyeuscaphic acid demonstrates notable hepatoprotective activity, effectively minimizing the leakage of intracellular enzymes, attenuating protein oxidation, and reducing apoptosis rates.		Others
T10662	Calcimycin hemicalcium salt	Antibiotic A-23187 hemicalcium salt,A-23187 hemicalcium salt	Others
	Calcimycin (A-23187) hemicalcium salt is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). It induces Ca2+-dependent cell death by increasing intracellular calcium concentration.		Others
T37977	Succinyladenosine
	Succinyladenosine is a biochemical marker of adenylosuccinase (ASL) deficiency. It is formed through the dephosphorylation of intracellular adenylosuccinic acid (S-AMP) by cytosolic 5-nucleotidase [1].
TN4085	Fupenzic acid		Others
	Fupenzic acid shows a significant decrease in intracellular melanin content in B16-F10 cells, and in culture media melanin.		Others
TMA1944	Protopine hydrochloride		EGFR , cAMP
	Protopine has antiplatelet effects,which is due to inhibition on thromboxane formation and phosphoinositides breakdown and then lead to the decrease of intracellular calcium concentration.Protopine seems to inhibit the h...		EGFR , cAMP
T75682	Cortisol sulfate
	Cortisol sulfate (Cortisol 21-sulfate) is a metabolite of Cortisol . Cortisol sulfate is a specific ligand for intracellular transcortin [1] [2] [3] .
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天然物製品

Dihydrocyclosporin A

T31467

Synonym: Dihydrocyclosporin-A

Target: Others, Endogenous Metabolite

i-Inositol

T0421

Synonym: Inositol,myo-Inositol,meso-Inositol

Target: Endogenous Metabolite

Spermine tetrahydrochloride

T3093

Synonym: Spermine Tetrahydrochloride,Neuridine tetrahydrochloride,Musculamine tetrahydrochloride,Gerontine tetrahydrochloride

Target: Others, Endogenous Metabolite

Bacoside A3

TN1425

Synonym:

Target: ATPase, ROS, P-gp

Cephaeline

TN1480

Synonym:

Target: Virus Protease, Influenza Virus, HIF

Tioconazole

T0146

Synonym: UK-20349,Vagistat

Target: Antibiotic, Antifection, Antifungal

Euphorbiasteroid

T3220

Synonym: Euphobiasteroid,Euphorbia factor L1

Target: Others, AMPK

Ammonium iron(III) citrate

T20819

Synonym: Ferric ammonium citrate

Target: Others, Ferroptosis

ATP disodium salt hydrate

T2812

Synonym: ATP disodium,ATP disodium salt,Adenosine disodium triphosphate

Target: Others, Endogenous Metabolite

Uridine 5′-triphosphate tris salt

T4922

Synonym: Uridine 5'-triphosphoric acid

Target: Others, Endogenous Metabolite

Fagomine

TQ0298

Synonym: D-Fagomine

Target: ROS, glycosidase

Synonym: NSC661583,NSC 661583,NSC-661583

Target: DNA/RNA Synthesis

(E/Z)-Squalene

T75636

Synonym: (E/Z)-Super Squalene,(E/Z)-AddaVax

Target:

Telocinobufagin

T4A2462

Synonym: Telobufotoxin,Telocinobufogenin

Target: Others

Rhamnose

T5120

Synonym: 6-Deoxyhexopyranose,6-Deoxy-L-mannose,alpha-L-Rhamnose

Target: Calcium Channel, Endogenous Metabolite

Synonym: Atipi,ATP disodium salt hydrate,Triphosphoric acid adenosine ester,Ara-ATP,Triphosphaden,Adenosine triphosphate;Ara-ATP,Adenosine triphosphate

Target: Endogenous Metabolite

Vinaxanthone

T70955

Synonym: SM-345431

Target: Phospholipase, Antibacterial

Deslanoside

T8183

Synonym: Desacetyllanatoside C,Deacetyllanatoside C

Target: ATPase, Drug Metabolite

2'-Hydroxy-3,4-dimethoxychalcone

TN7225

Synonym:

Target: Antioxidant, Parasite

Paraxanthine

T4973

Synonym: 1,7-DIMETHYLXANTHINE

Target: Endogenous Metabolite

Dihydrocurcumin

T3S1701

Synonym:

Target: PPAR, Fatty Acid Synthase

Sphingosine-1-phosphate

T21500

Synonym: S1P

Target: Endogenous Metabolite, S1P Receptor, LPL Receptor

Ionomycin

T7285

Synonym:

Target: Calcium Channel

Diphylline

T0892

Synonym: Dyphylline,Diprophylline

Target: PDE, Adenosine Receptor

Desoxyrhaponticin

TJS0387

Synonym: Deoxyrhapontin,Deoxyrhaponticin

Target: Apoptosis, Fatty Acid Synthase

Neferine

T5S1097

Synonym: (R)-1,2-Dimethoxyaporphine,(-)-Neferine

Target: Apoptosis, NF-κB, Autophagy

Guanosine 5'-triphosphate trisodium salt

T4969

Synonym: GTP Trisodium salt,5'-GTP trisodium salt

Target: Endogenous Metabolite

Isorhamnetin

T2836

Synonym: 3-methylquercetin,3'-Methylquercetin,Isorhamnetol,3'-Methoxyquercetin

Target: MEK, PI3K, Endogenous Metabolite

Synonym: Lutexin,Luteolin-8-glucoside

Target: ATPase, p38 MAPK, Calcium Channel, Akt, PI3K

DL-Glyceraldehyde

T4918

Synonym: Glyceric aldehyde

Target: ERK, p38 MAPK, Akt

Barlerin

T5S1632

Synonym: 8-O-Acetylshanzhiside methyl ester,ND01

Target: VEGFR, TNF, NF-κB, Akt, Caspase

Cornuside

T4S2326

Synonym: 7-Galloylsecologanol,7-O-Galloylsecologanol,Comuside

Target: ERK, p38 MAPK, NF-κB, JNK

(S)-Coriolic acid

T37974

Synonym: 13(S)-HODE

Target: Lipoxygenase, Mitochondrial Metabolism, PPAR

PE(18:1(9Z)/0:0)

T37280

Synonym:

Target: Endogenous Metabolite

3,8''-Biapigenin

TN1241

Synonym: 3,8'-Biapigenin

1β-Hydroxyeuscaphic acid

TN2543

Synonym: 1beta-Hydroxyeuscaphic acid

Target: Others

Calcimycin hemicalcium salt

T10662

Synonym: Antibiotic A-23187 hemicalcium salt,A-23187 hemicalcium salt

Protopine hydrochloride

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-00650	FIBP Protein, Human, Recombinant	Human	E. coli
	Acidic Fibroblast Growth Factor Intracellular-Binding Protein (FIBP) is highly expressed in the heart, skeletal muscle, and pancreas. Acidic Fibroblast Growth Factor is a member of the fibroblast growth factor (FGF) fam...
TMPJ-01363	CLIC5 Protein, Human, Recombinant (His)	Human	E. coli
	Chloride Intracellular Channel Protein 5 (CLIC5) is a single-pass membrane protein which belongs to the chloride channel CLIC family. It contains one GST C-terminal domain. Chloride intracellular channels are involved in...
TMPJ-00719	CLIC3 Protein, Human, Recombinant (His)	Human	E. coli
	Chloride intracellular channel protein 3 (CLIC3) is encoded by the CLIC3 gene. CLIC3 is a single-pass membrane protein which belongs to the chloride channel CLIC family. It contains one GST C-terminal domain and one GST ...
TMPY-04075	CLIC1 Protein, Human, Recombinant (His)	Human	E. coli
	Members of the CLIC family are largely soluble proteins that possess the intriguing property of spontaneous insertion into phospholipid bilayers to form integral membrane ion channels. Chloride intracellular channel 1 (C...
TMPJ-00666	CLIC2 Protein, Human, Recombinant (His)	Human	E. coli
	Chloride Intracellular Channel Protein 2 (CLIC2) is a critical component of all living cells; it regulatescellular traffic of Chloride ion and it can be inserted into membranes anf form chloride ion channels. Membrane in...
TMPY-01890	CLIC4 Protein, Human, Recombinant (His)	Human	E. coli
	Chloride intracellular channel protein 4, also known as Intracellular chloride ion channel protein p64H1 and CLIC4, is a member of the chloride channel CLIC family. It contains oneGST C-terminal domain. CLIC4 is a mem...
TMPY-02028	RON/CD136 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	The tyrosine kinase receptor, macrophage-stimulating 1 receptor (MST1R), a c-met-related tyrosine kinase, also known as the Ron receptor or CD136, controls cell survival and motility programs related to invasive growth. ...
TMPY-02575	PPAR gamma/PPARG Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Peroxisome proliferator-activated receptor gamma (PPARG), a nuclear hormone receptor, plays a critical role in the lipid and glucose homeostasis, adipocyte differentiation, as well as intracellular insulin-signaling even...
TMPY-02929	ENTPD2 Protein, Human, Recombinant (aa 29-460, His)	Human	Baculovirus Insect Cells
	NTPDase 2, also known as ENTPD2, belongs to the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). Members of E-NTPDase family are nucleotidases able to hydrolyze 5′-nucleoside tri- and/or diphosphates; ...
TMPY-01355	Transglutaminase 2/TGM2 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Protein-glutamine gamma-glutamyltransferase 2, also known as Tissue transglutaminase, Transglutaminase C, Transglutaminase-2, and TGM2, is a member of the transglutaminase superfamily. TGM2 plays a role in cell growth an...
TMPY-01964	CD16a Protein, Human, Recombinant (F176V, His)	Human	HEK293 Cells
	The Fc receptor with low affinity for IgG (FCGR3, or CD16) is encoded by 2 nearly identical genes, FCGR3A and FCGR3B, resulting in tissue-specific expression of alternative membrane-anchored isoforms. FCGR3A, it is also ...
TMPY-06983	IFN gamma Protein, Human, Recombinant (E. coli)	Human	E. coli
	IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ...
TMPY-02700	BCL2 Protein, Human, Recombinant (His)	Human	E. coli
	BCL2 (B-cell leukemia/lymphoma 2, N-Histidine-tagged), also known as Bcl-2, belongs to the Bcl-2 family. Bcl-2 family proteins regulate and contribute to programmed cell death or apoptosis. It is a large protein family a...
TMPY-04483	IRAK4 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Interleukin-1 receptor-associated kinase 4, also known as Renal carcinoma antigen NY-REN-64, IRAK-4, and IRAK4, is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, and Pelle subfamily. IRAK4...
TMPK-01369	S100B Protein, Canine, Recombinant (hFc)	Canine	HEK293 Cells
	S100B, a calcium-binding protein of the EF-hand type exerts both intracellular and extracellular functions.The intracellular, and extracellular, roles of S100B are attractive therapeutic targets for the treatment of both...
TMPH-00660	NikR Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Transcriptional repressor of the nikABCDE operon. Is active in the presence of excessive concentrations of intracellular nickel.
TMPH-02127	SNX16 Protein, Human, Recombinant (His)	Human	E. coli
	May be involved in several stages of intracellular trafficking. Plays a role in protein transport from early to late endosomes. Plays a role in protein transport to the lysosome. Promotes degradation of EGFR after EGF si...
TMPH-03667	Vaccinia virus (strain Copenhagen) OPG190 Protein (His)	VACV	P. pastoris (Yeast)
	Plays a role in the dissolution of the outermost membrane of extracellular enveloped virions (EEV) to allow virion entry into host cells. Participates also in wrapping intracellular mature virions (IMV) to form intracell...
TMPH-00630	Heat-labile enterotoxin A chain Protein, E. coli, Recombinant (His & Myc)	E. coli	E. coli
	The biological activity of the toxin is produced by the A chain, which activates intracellular adenyl cyclase.
TMPH-00631	Heat-labile enterotoxin B chain Protein, E. coli, Recombinant (His)	E. coli	E. coli
	The biological activity of the toxin is produced by the A chain, which activates intracellular adenyl cyclase.
TMPY-05055	GGH/Glutamyl hydrolase gamma Protein, Human, Recombinant (His)	Human	HEK293 Cells
	gamma-Glutamyl hydrolase (GGH) regulates intracellular folates and antifolates such as methotrexate (MTX) for proper nucleotide biosynthesis and antifolate-induced cytotoxicity, respectively. GGH is a ubiquitously-expres...
TMPH-00627	GAD-alpha Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Converts glutamate to gamma-aminobutyrate (GABA), consuming one intracellular proton in the reaction. The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acidic conditions...
TMPH-03666	Vaccinia virus (strain Copenhagen) OPG190 Protein (His & Myc)	VACV	E. coli
	Plays a role in the dissolution of the outermost membrane of extracellular enveloped virions (EEV) to allow virion entry into host cells. Participates also in wrapping intracellular mature virions (IMV) to form intracell...
TMPH-03291	FABP3 Protein, Rat, Recombinant (His & Myc)	Rat	HEK293 Cells
	FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.
TMPH-02913	Stefin-2 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	This is an intracellular thiol proteinase inhibitor. Stefin-2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 17.1 kDa and the accession num...
TMPH-02912	Stefin-1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	This is an intracellular thiol proteinase inhibitor. Stefin-1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16.3 kDa and the accession num...
TMPH-02851	PDIA2 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded protei...
TMPJ-00528	PPP1R1A Protein, Human, Recombinant (His)	Human	E. coli
	Protein Phosphatase 1 Regulatory Subunit 1A (PPP1R1A) is an inhibitor of protein-phosphatase 1. PPP1R1A is a cellular regulator of eIF2 alpha phosphorylation. In hormonal control of glycogen metabolism, IPP-1 protein pla...
TMPJ-00968	NAMPT Protein, Human, Recombinant (His)	Human	E. coli
	Pre-B cell colony enhancing factor (PBEF) was originally identified as a cytokine that potentiated the clonal expansion and differentiation of pre-B cells, but it is also acknowledged to be the ubiquitous intracellular e...
TMPH-03275	Cytoglobin Protein, Rat, Recombinant (His & Myc)	Rat	E. coli
	May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer. Plays a role in the development of liver fibrosis. Has a peroxidase activity.
TMPH-00844	HSD11B2 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids. HS...
TMPY-03266	COL4A3BP Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	COL4A3BP is a member of the StarD2 subfamily. It contains a pleckstrin homology domain at its amino terminus and a START domain towards the end of the molecule. COL4A3BP has a lipid-binding domain that mediates intrac...
TMPK-01251	L1R Protein, Monkeypox virus, Recombinant (His)	Monkeypox virus	E. coli
	L1R, a myristylated late gene product of vaccinia virus, is essential for formation of infectious intracellular mature virions (IMV). In its absence, only viral particles arrested at an immature stage are detected and no...
TMPJ-01142	CDO1 Protein, Human, Recombinant (His)	Human	E. coli
	Cysteine Dioxygenase Type 1 (CDO1) is a mammalian non-heme iron enzyme that belongs to the cysteine dioxygenase family. CDO1 is highly expressed in the liver and placenta, and has a low expression in heart, brain and pan...
TMPH-03433	ACB1 Protein, S. cerevisiae, Recombinant (His)	Saccharomyces cerevisiae	P. pastoris (Yeast)
	Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. ACB1 Protein, S. cerevisiae, Recombinant (His) is expressed in yeast with N-6xHis tag....
TMPH-01355	FXR1 Protein, Human, Recombinant (His)	Human	E. coli
	RNA-binding protein required for embryonic and postnatal development of muscle tissue. May regulate intracellular transport and local translation of certain mRNAs. FXR1 Protein, Human, Recombinant (His) is expressed in E...
TMPK-00774	TrkA Protein, Human, Recombinant (aa 33-417, His)	Human	HEK293 Cells
	TrkA, a tyrosine kinase receptor, is an essential component of the nerve growth factor (NGF) response pathway. The binding of NGF to the receptor induces receptor autophosphorylation and activation of intracellular signa...
TMPH-01060	Cathepsin F Protein, Human, Recombinant (His)	Human	E. coli
	Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis. Cathepsin F Protein, Human, Recombinant (His) is expressed...
TMPH-03032	Leucyl aminopeptidase Protein, Mycoplasma pneumoniae, Recombinant (His & SUMO)	Mycoplasma pneumoniae	E. coli
	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. Leucyl aminopeptidase Protein, Mycoplasma pneumon...
TMPH-00632	Heat-labile enterotoxin B chain Protein, E. coli, Recombinant (His & Myc)	E. coli	E. coli
	The biological activity of the toxin is produced by the A chain, which activates intracellular adenyl cyclase. Heat-labile enterotoxin B chain Protein, E. coli, Recombinant (His & Myc) is expressed in E. coli expression ...
TMPH-03011	EsxH Protein, Mycobacterium tuberculosis, Recombinant (His & SUMO)	Mycobacterium tuberculosis	E. coli
	EsxH, in complex with EsxG, disrupts ESCRT function and impairs host phagosome maturation, thereby promoting intracellular bacterial growth. The complex acts by interacting, via EsxH, with the host hepatocyte growth fact...
TMPJ-00089	CD3 epsilon/CD3e Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293 Cells
	T-Cell Surface Glycoprotein CD3 ε Chain (CD3ε) is a single-pass type I membrane protein. CD3ε contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3ε is a polypeptide encoded by the CD3E gene on chromosom...
TMPH-03261	Cathepsin D Protein, Rat, Recombinant (His & Myc)	Rat	E. coli
	Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation. Cathepsin D Protein, Rat, Recombinant (His & Myc) is exp...
TMPH-03329	Mcpt2 Protein, Rat, Recombinant (His & Myc)	Rat	E. coli
	This enzyme, isolated from small intestine, specifically inactivates the apo forms of a certain group of intracellular pyridoxal phosphate-requiring enzymes. It has chymotrypsin-like specificity towards small substrates....
TMPH-00268	GLTP Protein, Bovine, Recombinant (His)	Bovine	P. pastoris (Yeast)
	Accelerates the intermembrane transfer of various glycolipids. Catalyzes the transfer of various glycosphingolipids between membranes but does not catalyze the transfer of phospholipids. May be involved in the intracellu...
TMPY-00517	LSP1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	LSP1 (Lymphocyte Specific Protein 1) is a Protein Coding gene. This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regula...
TMPJ-01248	Cytoglobin/CYGB Protein, Human, Recombinant (His)	Human	E. coli
	Cytoglobin is a ubiquitously globin protein that belongs to the globin family. The highest expressed in heart, stomach, bladder and small intestine. CYGB acts a protector under conditions of oxidative stress. CYGB may be...
TMPH-03662	Vaccinia virus (strain Copenhagen) OPG161 Protein (A33R, E. coli, His)	VACV	E. coli
	Coordinates the incorporation of A36 into intracellular enveloped virion (IEV) membranes and, subsequently, the production of actin tails. Therefore plays an essential role in efficient cell-to-cell spread of viral parti...
TMPY-03308	ADAM17 Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	ADAM17 is a member of the ADAM protein family of disintegrins and metalloproteases. ADAM17 is ubiquitously expressed in the human colon, with increased activity in the colonic mucosa of patients with ulcerative coliti...
TMPH-03450	Nicotinamidase/PNC1 Protein, S. cerevisiae, Recombinant	Saccharomyces cerevisiae	E. coli
	Catalyzes the deamidation of nicotinamide, an early step in the NAD(+) salvage pathway. Positively regulates SIR2-mediated silencing and longevity by preventing the accumulation of intracellular nicotinamide, an inhibito...
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FIBP Protein, Human, Recombinant

TMPJ-00650

Species: Human

Expression System: E. coli

CLIC5 Protein, Human, Recombinant (His)

TMPJ-01363

Species: Human

Expression System: E. coli

CLIC3 Protein, Human, Recombinant (His)

TMPJ-00719

Species: Human

Expression System: E. coli

CLIC1 Protein, Human, Recombinant (His)

TMPY-04075

Species: Human

Expression System: E. coli

CLIC2 Protein, Human, Recombinant (His)

TMPJ-00666

Species: Human

Expression System: E. coli

CLIC4 Protein, Human, Recombinant (His)

TMPY-01890

Species: Human

Expression System: E. coli

RON/CD136 Protein, Human, Recombinant (His)

TMPY-02028

Species: Human

Expression System: HEK293 Cells

PPAR gamma/PPARG Protein, Human, Recombinant (His & GST)

TMPY-02575

Species: Human

Expression System: Baculovirus Insect Cells

ENTPD2 Protein, Human, Recombinant (aa 29-460, His)

TMPY-02929

Species: Human

Expression System: Baculovirus Insect Cells

Transglutaminase 2/TGM2 Protein, Human, Recombinant (His)

TMPY-01355

Species: Human

Expression System: Baculovirus Insect Cells

CD16a Protein, Human, Recombinant (F176V, His)

TMPY-01964

Species: Human

Expression System: HEK293 Cells

IFN gamma Protein, Human, Recombinant (E. coli)

TMPY-06983

Species: Human

Expression System: E. coli

BCL2 Protein, Human, Recombinant (His)

TMPY-02700

Species: Human

Expression System: E. coli

IRAK4 Protein, Human, Recombinant (His)

TMPY-04483

Species: Human

Expression System: Baculovirus Insect Cells

S100B Protein, Canine, Recombinant (hFc)

TMPK-01369

Species: Canine

Expression System: HEK293 Cells

NikR Protein, E. coli, Recombinant (His)

TMPH-00660

Species: E. coli

Expression System: E. coli

SNX16 Protein, Human, Recombinant (His)

TMPH-02127

Species: Human

Expression System: E. coli

Vaccinia virus (strain Copenhagen) OPG190 Protein (His)

TMPH-03667

Species: VACV

Expression System: P. pastoris (Yeast)

Heat-labile enterotoxin A chain Protein, E. coli, Recombinant (His & Myc)

TMPH-00630

Species: E. coli

Expression System: E. coli

Heat-labile enterotoxin B chain Protein, E. coli, Recombinant (His)

TMPH-00631

Species: E. coli

Expression System: E. coli

GGH/Glutamyl hydrolase gamma Protein, Human, Recombinant (His)

TMPY-05055

Species: Human

Expression System: HEK293 Cells

GAD-alpha Protein, E. coli, Recombinant (His)

TMPH-00627

Species: E. coli

Expression System: E. coli

Vaccinia virus (strain Copenhagen) OPG190 Protein (His & Myc)

TMPH-03666

Species: VACV

Expression System: E. coli

FABP3 Protein, Rat, Recombinant (His & Myc)

TMPH-03291

Species: Rat

Expression System: HEK293 Cells

Stefin-2 Protein, Mouse, Recombinant (His)

TMPH-02913

Species: Mouse

Expression System: E. coli

Stefin-1 Protein, Mouse, Recombinant (His)

TMPH-02912

Species: Mouse

Expression System: E. coli

PDIA2 Protein, Mouse, Recombinant (His & SUMO)

TMPH-02851

Species: Mouse

Expression System: E. coli

PPP1R1A Protein, Human, Recombinant (His)

TMPJ-00528

Species: Human

Expression System: E. coli

NAMPT Protein, Human, Recombinant (His)

TMPJ-00968

Species: Human

Expression System: E. coli

Cytoglobin Protein, Rat, Recombinant (His & Myc)

TMPH-03275

Species: Rat

Expression System: E. coli

HSD11B2 Protein, Human, Recombinant (His)

TMPH-00844

Species: Human

Expression System: P. pastoris (Yeast)

COL4A3BP Protein, Human, Recombinant (His & GST)

TMPY-03266

Species: Human

Expression System: Baculovirus Insect Cells

L1R Protein, Monkeypox virus, Recombinant (His)

TMPK-01251

Species: Monkeypox virus

Expression System: E. coli

CDO1 Protein, Human, Recombinant (His)

TMPJ-01142

Species: Human

Expression System: E. coli

ACB1 Protein, S. cerevisiae, Recombinant (His)

TMPH-03433

Species: Saccharomyces cerevisiae

Expression System: P. pastoris (Yeast)

FXR1 Protein, Human, Recombinant (His)

TMPH-01355

Species: Human

Expression System: E. coli

TrkA Protein, Human, Recombinant (aa 33-417, His)

TMPK-00774

Species: Human

Expression System: HEK293 Cells

Cathepsin F Protein, Human, Recombinant (His)

TMPH-01060

Species: Human

Expression System: E. coli

Leucyl aminopeptidase Protein, Mycoplasma pneumoniae, Recombinant (His & SUMO)

TMPH-03032

Species: Mycoplasma pneumoniae

Expression System: E. coli

Heat-labile enterotoxin B chain Protein, E. coli, Recombinant (His & Myc)

TMPH-00632

Species: E. coli

Expression System: E. coli

EsxH Protein, Mycobacterium tuberculosis, Recombinant (His & SUMO)

TMPH-03011

Species: Mycobacterium tuberculosis

Expression System: E. coli

CD3 epsilon/CD3e Protein, Human, Recombinant (hFc & Avi), Biotinylated

TMPJ-00089

Species: Human

Expression System: HEK293 Cells

Cathepsin D Protein, Rat, Recombinant (His & Myc)

TMPH-03261

Species: Rat

Expression System: E. coli

Mcpt2 Protein, Rat, Recombinant (His & Myc)

TMPH-03329

Species: Rat

Expression System: E. coli

GLTP Protein, Bovine, Recombinant (His)

TMPH-00268

Species: Bovine

Expression System: P. pastoris (Yeast)

LSP1 Protein, Human, Recombinant (His)

TMPY-00517

Species: Human

Expression System: HEK293 Cells

Cytoglobin/CYGB Protein, Human, Recombinant (His)

TMPJ-01248

Species: Human

Expression System: E. coli

Vaccinia virus (strain Copenhagen) OPG161 Protein (A33R, E. coli, His)

TMPH-03662

Species: VACV

Expression System: E. coli

ADAM17 Protein, Rat, Recombinant (His)

TMPY-03308

Species: Rat

Expression System: HEK293 Cells

Nicotinamidase/PNC1 Protein, S. cerevisiae, Recombinant

TMPH-03450

Species: Saccharomyces cerevisiae

Expression System: E. coli

--------- More ---------

カタログ番号	製品名
L2170	Immuno-Oncology Compound Library	449 compounds
	A unique collection of 449 compounds acting on immune-oncology therapeutic targets can be used for high throughput and high content screening；
L1310	Cytoskeletal Signaling Pathway Compound Library	759 compounds
	A unique collection of 759 cytoskeleton-related compounds, can be used for HTS and HCS；
L2800	Serotonin Receptor-Targeted Compound Library	268 compounds
	A unique collection of 268 compounds targeting serotonin receptors for high throughput screening and high content screening;
L1300	PI3K-AKT-mTOR Compound Library	420 compounds
	A unique collection of 420 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with PI3K/Akt/mTOR signaling;
L3300	Histamine & Melatonin Receptor-Targeted Compound Library	153 compounds
	A unique collection of 153 compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS) for new drugs;
L7200	Calcium Channel Compound Library	140 compounds
	A unique collection of 140 calcium channel blockers and agonists for high throughput and high content screening;
L2550	Glutamine Metabolism Compound Library	565 compounds
	A unique collection of 565 glutamine metabolism related compounds can be used for high throughput screening (HTS) and high content screening (HCS), and also is an effective tool for research in glutamine metabolism and ...
L4700	Immunology/Inflammation Compound Library	4720 compounds
	A unique collection of 4720 anti-inflammation compounds effective for high throughput screening and high content screening.
L7110	Anti-Hypertension Compound Library	678 compounds
	678 hypertension-related small molecules for high-throughput and high-content screening.
L9840	Anti-Alzheimer's Disease Compound Library	986 compounds
	A unique collection of 986 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS.

ライブラリー

Immuno-Oncology Compound Library

L2170

Compounds: 449

Cytoskeletal Signaling Pathway Compound Library

L1310

Compounds: 759

Serotonin Receptor-Targeted Compound Library

L2800

Compounds: 268

PI3K-AKT-mTOR Compound Library

L1300

Compounds: 420

Histamine & Melatonin Receptor-Targeted Compound Library

L3300

Compounds: 153

Calcium Channel Compound Library

L7200

Compounds: 140

Glutamine Metabolism Compound Library

L2550

Compounds: 565

Immunology/Inflammation Compound Library

L4700

Compounds: 4720

Anti-Hypertension Compound Library

L7110

Compounds: 678

Anti-Alzheimer's Disease Compound Library

L9840

Compounds: 986

Isotope Products

カタログ番号	製品名	別名
T36895	5-Fluorouracil-13C,15N2	5-Fluorouracil-13C,15N2
	5-Fluorouracil-13C,15N2 is intended for use as an internal standard for the quantification of 5-flurouracil by GC- or LC-MS. 5-Fluorouracil is a pyrimidine analog that irreversibly inhibits thymidylate synthase, blocking...
T35695	Oleic Acid-13C
	Oleic acid-13C is intended for use as an internal standard for the quantification of oleic acid by GC- or LC-MS. Oleic acid is a monounsaturated fatty acid and a major component of membrane phospholipids that has been fo...
T35790	Palmitic acid-1,2,3,4-13C4	Palmitic Acid-13C (C1, C2, C3, and C4 labeled)
	Palmitic acid-13C (C1, C2, C3, and C4 labeled) is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a common 16-carbon saturated fat that represents 10-20%...

Isotope Products

5-Fluorouracil-13C,15N2

T36895

Synonym: 5-Fluorouracil-13C,15N2

Palmitic acid-1,2,3,4-13C4

T35790

Synonym: Palmitic Acid-13C (C1, C2, C3, and C4 labeled)

Target: