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Search Results for " LPS "

ターゲット

Lipase

220

阻害剤

192

天然化合物

106

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T4052	KML29		Lipase
	KML29 is highly selective and effective monoacylglycerol lipase (MAGL) inhibitor. It has effective inhibition of human/mouse/rat MAGL (IC50: 5.9/15/43 nM). It has not inhibitory for FAAH (IC50 > 50 μM). It also effective...		Lipase
T13231L	Trovafloxacin mesylate		Others , DNA/RNA Synthesis , Topoisomerase , Antibacterial
	Trovafloxacin is a broad-spectrum fluoroquinolone antibiotic that inhibits the activity of DNA gyrase and topoisomerase IV, enzymes involved in DNA replication. It also acts as an effective and specific inhibitor of the ...		Others , DNA/RNA Synthesis , Topoisomerase , Antibacterial
T6610	XI-006	NSC 207895	Mdm2 , p53
	XI-006 (XI-006) suppresses MDMX with IC50 of 2.5 μM, leading to enhanced p53 stabilization/activation and DNA damage, and also regulates MDM2, an E3 ligase.		Mdm2 , p53
T7704	KY-226		Phosphatase
	KY-226 is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B)(IC50: 0.25 μM,)		Phosphatase
T14943	CGP60474		VEGFR , CDK , PKC
	CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC. CGP60474 is also a highly potent anti-endotoxemic agent and inhibits cyclin-dependent kinase (CDK) potently.		VEGFR , CDK , PKC
T21694	(R)-Lisofylline	(R)-Lisophylline	STAT
	(R)-Lisofylline ((R)-Lisophylline) is an inhibitor of lysophosphatidic acid acyltransferase (IC50 = 0.6 µM). (R)-Lisofylline interrupts IL-12 signaling-mediated STAT4 activation and can be used in studies about the treat...		STAT
T7596	Firocoxib	ML 1785713	COX
	Firocoxib (ML 1785713) is a selective non-steroidal inhibitor of cycooxygenase-2 (COX-2) (IC50 of 0.13 μM), with anti-inflammatory for use in dogs and horses.		COX
T41302	Itaconate-alkyne	ITalk	Others
	Itaconate-alkyne (ITalk) is a bioorthogonal probe for quantitative and site-specific chemoproteomic profiling of itaconate in inflammatory macrophages and enables biochemical evaluation and proteomic analysis of its dire...		Others
T13324	VUF11207 fumarate		CXCR , Arrestin
	VUF11207 fumarate is an agonist of CXCR7 and a high-potency ligand of CXCR7 (pKi: 8.1).		CXCR , Arrestin
T11139	(E/Z)-BCI	NSC 150117	Apoptosis , Phosphatase
	(E/Z)-BCI (NSC-150117), a dual-specificity phosphatase 6 (DUSP6) inhibitor with anti-inflammatory properties, reduces LPS-induced inflammatory mediators and ROS production in macrophage cells by activating the Nrf2 signa...		Apoptosis , Phosphatase
T6927	Pamapimod	R1503,Ro4402257	p38 MAPK , Autophagy
	Pamapimod (R1503) (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase. It inhibits p38α and p38β enzymatic activity with IC50 values of 0.014±0.002 and 0.48± 0.04 microM, respectiv...		p38 MAPK , Autophagy
T2923	Apremilast	CC-10004	Apoptosis , TNF , PDE
	Apremilast (CC-10004) (CC-10004) is a potent and orally active PDE4 (IC50=74 nM) with anti-inflammation activities.		Apoptosis , TNF , PDE
T0947	Dexamethasone acetate	Dexamethasone 21-acetate,Dexamethason acetate,NSC 39471	Glucocorticoid Receptor , Mitophagy , IL Receptor , Annexin A , NOS , Antibacterial , Autophagy
	Dexamethasone acetate (NSC 39471) is the acetate salt form of Dexamethasone, a synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addition to binding to specific nuclear steroid receptors, dexa...
T2131	Articaine hydrochloride	Ultracaine,Articaine HCl,Hoe-045	Sodium Channel
	Articaine hydrochloride (Hoe-045) is a thiophene-containing local anesthetic pharmacologically similar to MEPIVACAINE.		Sodium Channel
TP1938	RS 09		TLR
	TLR4 agonist. Promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. Acts as an adjuvant in vivo; enhances X-15 specific antibody serum concentrations, when adm...		TLR
T8929	BC1618	2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]-	Mitophagy , Others , E1/E2/E3 Enzyme , AMPK
	BC1618 (2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]-) is an orally active Fbxo48 inhibitor that stimulates Ampk-dependent signaling. It promotes mitochondrial fission, promotes autophagy and imp...		Mitophagy , Others , E1/E2/E3 Enzyme , AMPK
T13231	Trovafloxacin		DNA gyrase , Topoisomerase , Antibacterial , Antibiotic
	Trovafloxacin is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive.		DNA gyrase , Topoisomerase , Antibacterial , Antibiotic
T18916	ALPS	N-Ethyl-N-sulfopropylaniline sodium salt	Others
	ALPS (N-Ethyl-N-sulfopropylaniline sodium salt) (N-Ethyl-N-sulfopropylaniline sodium salt) is a bio-chemical reagents/chromogenic reagent.		Others
T19459	N1-Methylpseudouridine	1-Methylpseudouridine	Others
	N1-Methylpseudouridine (1-Methylpseudouridine) is a methylpseudouridine and enhances translation through eIF2α-dependent and independent mechanisms by increasing ribosome density in mRNA.		Others
TNU1576	2’,3’-Bis-O-(t-butyldimethylsilyl)-N1-methylpseudouridine
	2’,3’-Bis-O-(t-butyldimethylsilyl)-N1-methylpseudouridine is a useful organic compound for research related to life sciences and the catalog number is TNU1576.
T73736	N1-Methylpseudouridine-5′-triphosphate tetralithium
	N1-Methylpseudouridine-5′-triphosphate tetralithium, also known as 1-Methylpseudouridine-5′-triphosphate tetralithium, is a nucleobase-modified nucleotide. It is utilized in the synthesis of mRNA to decrease immunogenici...
T124720	O-Methylpsychotrine
	O-Methylpsychotrine is a useful organic compound for research related to life sciences. The catalog number is T124720 and the CAS number is 523-01-3.
TNU0079	N1-Propargylpseudouridine
	N1-Propargylpseudouridine is a Nucleoside Derivative - C-nucleoside; N-Alkylated nucleoside.
TNU0062	N1-Ethylpseudouridine
	N1-Ethylpseudouridine is a Nucleoside Derivative - C-nucleoside; N-Methylated nucleoside.
TNU0078	N1-Methyl-N3-[(2S)-2-(t-butoxycarbonyl)amino-3-(t-butoxycarbonyl)] propylpseudouridine
	N1-Methyl-N3-[(2S)-2-(t-butoxycarbonyl)amino-3-(t-butoxycarbonyl)] propylpseudouridine is a Nucleoside Derivative - C-nucleoside; N-Alkylated nucleoside.
T40452	N-Acetylpsychosine	N-Acetylpsychosine,C2 Galactosylceramide (d18:1/2:0)
	N-Acetylpsychosine, also known as α-galactosylated C2-ceramide (d18:1/2:0), exhibits immunostimulatory properties. This compound, N-Acetylpsychosine, holds potential as a valuable tool for studying the mechanisms of apop...
T73735	N1-Methylpseudouridine-5′-triphosphate
	N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) is a modified nucleotide that enhances mRNA synthesis by minimizing immunogenicity and enhancing stability.
TNU0077	N1-Cyclopropylmethylpseudouridine
	N1-Cyclopropylmethylpseudouridine is a Nucleoside Derivative - C-nucleoside; N-Alkylated nucleoside.
TNU0076	6-Methylpseudouridine
	6-Methylpseudouridine is a Nucleoside Derivative - C-nucleoside.
TNU0038	3-Methylpsedouridine
	Nucleoside Derivatives - C-nucleosides, N-Methyl nucleosides; Naturally modified Ribo-nucleosides
T66958	DLPS
	DLPS is a useful organic compound for research related to life sciences and the catalog number is T66958.
T73737	N1-Methylpseudouridine-5′-triphosphate trisodium
	N1-Methylpseudouridine-5′-triphosphate trisodium (1-Methylpseudouridine-5′-triphosphate), a modified nucleotide, is utilized in the synthesis of mRNA to lower immunogenicity and enhance stability [1].
T22469	1-Methylpsilocin		Others
	5-HT2C agonist, potent and selective		Others
T125894	Didemethylpseudoaspidin AA
	Didemethylpseudoaspidin AA is a useful organic compound for research related to life sciences and the catalog number is T125894.
TNU0749	N1-Allylpseudouridine
	N1-Allylpseudouridine is a Nucleoside Derivative - C-nucleoside; N-Alkylated nucleoside.
T37292	M62812		TLR
	TLR4 inhibitor. Inhibits LPS-induced NF-κB activation in HEK293 cells (IC50 = 2.4 μg/mL). Also inhibits LPS-induced cytokine production and procoagulant effects in PBMCs and HUVECs. Prolongs survival in a mouse septic sh...		TLR
T14939L	CGP-42112 acetate	CGP-42112 acetate(127060-75-7 Free base）	RAAS
	CGP-42112 acetate is a potent angiotensin receptor AT2 agonist that inhibits the increase in protein kinase A activity produced by LPS.		RAAS
T21853	(E)-AG 556		EGFR
	AG 556 is a selective inhibitor of EGFR and blocks LPS-induced TNF-α production.		EGFR
T9581	ARRY-797	ARRY-371797	IL Receptor , p38 MAPK
	ARRY-797 (ARRY-371797) is a potent and selective p38α inhibitor and inhibits LPS-Induced IL-6.		IL Receptor , p38 MAPK
T75174	Anti-inflammatory agent 42		IL Receptor , TNF
	Anti-inflammatory agent 42 has anti-inflammatory activity and inhibits the expression of TNF-α and IL-6 in LPS-stimulated macrophages.		IL Receptor , TNF
T77484	Atibuclimab		TNF
	Atibuclimab is a chimeric monoclonal antibody targeting CD14, consisting of a mouse variable region and a human IgG4 Fc region. Atibuclimab can be used to treat amyotrophic lateral sclerosis. Atibuclimab reduces LPS-indu...		TNF
T27841	Lobeglitazone Sulfate	CKD501 Sulfate,CKD501,CKD-501 Sulfate,CKD 501 Sulfate,CKD 501,CKD-501,Lobeglitazone Sulfate. trade name Duvie, Chong Kun Dang	NOD
	Lobeglitazone Sulfate（CKD-501 Sulfate） is a novel thiazolidinedione with anti-inflammatory activity that inhibits LPS-induced NLRP3 inflammasome activation and hepatic inflammation, and can be used in the study of type 2...		NOD
T36524	IKK2-IN-4	5-Phenyl-2-ureidothiophene-3-carboxylic Acid Amide,IKK2 Inhibitor IV	IκB/IKK , TNF
	IKK2-IN-4(IKK2 Inhibitor VI) is a highly potent IKK-2 inhibitor with an IC50 value of 25 nM. IKK2-IN-4 inhibited the production of TNF-α in PBMC induced by LPS.		IκB/IKK , TNF
T1076	Dexamethasone	MK 125,Prednisolone F,NSC 34521,Hexadecadrol	Glucocorticoid Receptor , Mitophagy , IL Receptor , SARS-CoV , Antibacterial , Antibiotic , Autophagy , Complement System
	Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist and an IL receptor modulator. Dexamethasone has anti-inflammatory and immunosuppressive activity and induces autophagy. Dexamethasone inhibits LPS-induced...
T64359	Anti-inflammatory agent 36		Immunology/Inflammation related
	Anti-inflammatory agent 36 is an anti-inflammatory agent. It exhibited dose-dependent inhibition of LPS-induced release of TNF-a and IL-6 in active RAW 264.7 mouse macrophages, IC50=3.69uM and 3.68uM, respectively.		Immunology/Inflammation related
T10866	Cot inhibitor-2		TNF , MAPK
			TNF , MAPK
T5101	BW-A 78U	BW-A78U	PDE
	BW-A 78U is a PDE4 inhibitor (IC50: 3 μM). It is not inhibition on the lipopolysaccharide (LPS)-induced TNF-α release.		PDE
T9543	Syk Inhibitor II hydrochloride		Others
	The impact of spleen tyrosine kinase (Syk) signaling might be prominent in lupus because (i) Syk is a shared downstream signaling molecule among circulating immune complex, LPS, and (1→3)-β-D-glucan (BG), and (ii) all of...		Others
T23636	Adenosine N1-oxide	ANO,1-Oxoadenosine,Adenosine N1 oxide,Adenosine, 1-oxide	Immunology/Inflammation related
	Adenosine N1-oxide (1-Oxoadenosine), which is found in royal jelly, inhibited the secretion of inflammatory mediators by activated macrophages and reduced lethality in lipopolysaccharide (LPS)-induced endotoxin shock.		Immunology/Inflammation related
T3680	ISO-1	MIF Antagonist,ISO 1	Others
	ISO-1 (MIF Antagonist) is an inhibitor of the dopachrome tautomerase activity, blocks the activation of NF-κB and TNF-α secretion from LPS-treated macrophages.		Others

Compounds

Trovafloxacin mesylate

T13231L

Synonym:

Target: Others, DNA/RNA Synthesis, Topoisomerase, Antibacterial

Target: VEGFR, CDK, PKC

(R)-Lisofylline

T21694

Synonym: (R)-Lisophylline

Target: CXCR, Arrestin

(E/Z)-BCI

T11139

Synonym: NSC 150117

Target: Apoptosis, Phosphatase

Pamapimod

T6927

Synonym: R1503,Ro4402257

Target: p38 MAPK, Autophagy

Apremilast

T2923

Synonym: CC-10004

Target: Apoptosis, TNF, PDE

Dexamethasone acetate

T0947

Synonym: Dexamethasone 21-acetate,Dexamethason acetate,NSC 39471

Target: Glucocorticoid Receptor, Mitophagy, IL Receptor, Annexin A, NOS, Antibacterial, Autophagy

Articaine hydrochloride

T2131

Synonym: Ultracaine,Articaine HCl,Hoe-045

Target: Sodium Channel

Synonym: 2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]-

Target: Mitophagy, Others, E1/E2/E3 Enzyme, AMPK

Trovafloxacin

T13231

Synonym:

Target: DNA gyrase, Topoisomerase, Antibacterial, Antibiotic

ALPS

T18916

Synonym: N-Ethyl-N-sulfopropylaniline sodium salt

Target: Others

N1-Methylpseudouridine

T19459

Synonym: 1-Methylpseudouridine

Target: Others

2’,3’-Bis-O-(t-butyldimethylsilyl)-N1-methylpseudouridine

TNU1576

Synonym:

Target:

N1-Methylpseudouridine-5′-triphosphate tetralithium

N1-Propargylpseudouridine

TNU0079

Synonym:

Target:

N1-Ethylpseudouridine

TNU0062

Synonym:

Target:

N1-Methyl-N3-[(2S)-2-(t-butoxycarbonyl)amino-3-(t-butoxycarbonyl)] propylpseudouridine

Synonym: N-Acetylpsychosine,C2 Galactosylceramide (d18:1/2:0)

Target:

N1-Methylpseudouridine-5′-triphosphate

T73735

Synonym:

Target:

N1-Cyclopropylmethylpseudouridine

TNU0077

Synonym:

Target:

6-Methylpseudouridine

N1-Methylpseudouridine-5′-triphosphate trisodium

Didemethylpseudoaspidin AA

T125894

Synonym:

Target:

N1-Allylpseudouridine

Synonym: CGP-42112 acetate(127060-75-7 Free base）

Target: IL Receptor, p38 MAPK

Anti-inflammatory agent 42

T75174

Synonym:

Target: IL Receptor, TNF

Lobeglitazone Sulfate

T27841

Synonym: CKD501 Sulfate,CKD501,CKD-501 Sulfate,CKD 501 Sulfate,CKD 501,CKD-501,Lobeglitazone Sulfate. trade name Duvie, Chong Kun Dang

Target: NOD

IKK2-IN-4

T36524

Synonym: 5-Phenyl-2-ureidothiophene-3-carboxylic Acid Amide,IKK2 Inhibitor IV

Target: IκB/IKK, TNF

Dexamethasone

T1076

Synonym: MK 125,Prednisolone F,NSC 34521,Hexadecadrol

Target: Glucocorticoid Receptor, Mitophagy, IL Receptor, SARS-CoV, Antibacterial, Antibiotic, Autophagy, Complement System

Anti-inflammatory agent 36

T64359

Synonym:

Target: Immunology/Inflammation related

Syk Inhibitor II hydrochloride

Synonym: ANO,1-Oxoadenosine,Adenosine N1 oxide,Adenosine, 1-oxide

Target: Immunology/Inflammation related

ISO-1

T3680

Synonym: MIF Antagonist,ISO 1

Target: Others

カタログ番号	製品名	別名	ターゲット
T11855	Lipopolysaccharides	LPS	Others
	Lipopolysaccharides (LPS) is a natural product, an endotoxin derived from the outer leaflet of the outer membrane of Gram-negative bacteria. Lipopolysaccharides are highly immunogenic antigens that enhance the immune res...		Others
T41078	Lipopolysaccharides, Escherichiacoli (11C)	LPS E. coli O55:B5,Lipopolysaccharide, E. coli O111:B4	Others
	Lipopolysaccharides, Escherichiacoli (11C) (LPS E. coli O55:B5), a macromolecular component of the outer membrane of Gram-negative bacteria, is composed of three regions: a lipid A, an oligosaccharide core, and an O-spec...		Others
T6S1572	Sauchinone		ERK , p38 MAPK , NF-κB
	1. Sauchinone is a useful adjunctive treatment for bacterial infection. 2. Sauchinone, an active lignan found in Saururus chinensis, to regulate the activation of HSCs, to prevent liver fibrosis, and to inhibit oxidative...		ERK , p38 MAPK , NF-κB
TQ0218	Deoxyandrographolide	14-deoxyandrographolide	IL Receptor , TNF
			IL Receptor , TNF
T4592	TOMATIDINE HYDROCHLORIDE	Tomatidine,Tomatidine HCl	Others , NF-κB , JNK , Autophagy
	Tomatidine hydrochloride (Tomatidine HCl) is a steriodal alkaloid structurally similar to Cyclopamine but does not inhibit hedgehog pathway. May be used as a negative control for Cyclopamine and KAAD-Cyclopamine. Tomatid...		Others , NF-κB , JNK , Autophagy
T2988	(-)-Epigallocatechin Gallate	Epigallocatechol Gallate,EGCG	Ferroptosis , Reactive Oxygen Species , HIV Protease , Mitochondrial Metabolism , Endogenous Metabolite , Autophagy
	(-)-Epigallocatechin Gallate (EGCG) is an antioxidant polyphenol flavonoid that inhibits telomerase and DNA methyltransferase. (-)-Epigallocatechin Gallate (EGCG) blocks the activation of EGF receptors and HER-2 receptor...
TN6796	2'-FUCOSYLLACTOSE	2'-Fucosyl-D-lactose	Others
	2'-FUCOSYLLACTOSE (2'-Fucosyl-D-lactose) is a fucose-containing oligosaccharide.		Others
T6S0117	Avicularin	Fenicularin	ERK
	Avicularin (Fenicularin) has anti-allergic, anti-inflammatory, hepatoprotective, antioxidant, anti-tumor and other activities. It ameliorates human hepatocellular carcinoma by modulating the activities of NF-κB(p65), COX...		ERK
TN6714	Geranylgeraniol	FT-0626663,Tetraprenol,CJ24095,CJ 24095,FT0626663,CJ-24095	Apoptosis
	Geranylgeraniol (FT0626663) is an isoprenoid found in fruits, vegetables, and grains, including rice. Geranylgeraniol (FT0626663) inhibits growth and induces apoptosis of various tumor cells. Geranylgeraniol (FT0626663) ...		Apoptosis
TCS2170	2,5-Dihydroxyacetophenone	Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP	ERK , NF-κB , Tyrosinase
	1. 2,5-Dihydroxyacetophenone (Quinacetophenone) possess anti-anxiety, and neuroprotective qualities. 2. 2,5-Dihydroxyacetophenone (Quinacetophenone) reatment can induce a sustained activation of JNK, ERK1/2, and p38 MAPK...		ERK , NF-κB , Tyrosinase
TN1102	Physalin L		Others , NO Synthase
	Physalin L is a natural product,it shows a distinct fluorescence spot under UV 365 nm with good separation.		Others , NO Synthase
TN1818	Kaempferol 3-O-β-D-glucuronide	Kaempferol-3-O-glucuronide,Kaempferol-3-beta-O-glucuronide,Kaempferol-3-glucuronide	IL Receptor
	Kaempferol 3-O-β-D-glucuronide (Kaempferol-3-beta-O-glucuronide)e has antioxidant activity. Flavonoid glucuronides can be deconjugated by microsomal α²-glucuronidase from various human cells.		IL Receptor
TN1554	Deacetylpseudolaric acid A		Others
	Deacetylpseudolaric acid A is a natural product from Pseudolarix amabilis.		Others
TN5170	Triacetylpseurotin A		Others
	Triacetylpseurotin A is a natural product for research related to life sciences. The catalog number is TN5170 and the CAS number is 77353-57-2.		Others
TN3281	8-Hydroxy-5-O-beta-D-glucopyranosylpsoralen		Others
	8-Hydroxy-5-O-beta-D-glucopyranosylpsoralen is a natural product of Psoralea, Fabaceae. The catalog number is TN3281 and the CAS number is 425680-98-4. 8-Hydroxy-5-O-beta-D-glucopyranosylpsoralen can be used as a referen...		Others
T83239	7-O-Primverosylpseudobaptigenin
	7-O-Primverosylpseudobaptigenin, a natural product, can be isolated from the alcoholic extract of Amur maackia roots [1].
T62625	11-O-Methylpseurotin A
	11-O-Methylpseurotin A, a mixed polyketide synthase-non-ribosomal peptide synthase (PKS/NRPS) compound, selectively inhibited Hof1-deficient strains.
TN1219	20-Hydroxyganoderic acid G
	20-Hydroxyganoderic acid G is a lanosterane triterpenoid obtained from the ethanolic extract of Ganoderma curtisii (Ganoderma curtisii) cotyledons. 20-Hydroxyganoderic Acid G inhibited LPS-activated BV-2 microglia, with ...
T6S1543	Dehydrodiisoeugenol		Others , NF-κB , COX , Antibacterial
	1. Dehydrodiisoeugenol has anti-inflammatory activity. (1). Dehydrodiisoeugenol inhibited the expression of the COX-2 in RAW264.7 murine macrophages stimulated with LPS. (2). Dehydrodiisoeugenol inhibited LPS-stimulated ...		Others , NF-κB , COX , Antibacterial
T5S0734	Desmethoxyyangonin	Desmethoxy yangonin,Demethoxyyangonin,5,6-Dehydrokavain	Others , Monoamine Oxidase
	1. Desmethoxyyangonin (5,6-Dehydrokavain) protects LPS or LPS/D-GalN-induced damages in cell or liver tissues mainly through de-regulating IKK/NFκB and Jak2/STAT3 signaling pathways. 2. The induction of CYP3A23 by dihydr...		Others , Monoamine Oxidase
TN1553	Deacetyl ganoderic acid F		Others
	Deacetyl ganoderic acid F (DeGA F), a triterpenoid extracted from Ganoderma lucidum, inhibits lipopolysaccharide (LPS)-induced inflammation in vitro and in vivo.		Others
T3039	Hederagenin	Hederagenic acid,Astrantiagenin E,Caulosapogenin,Hederagenol	Others
	Hederagenin (Hederagenol) is a triterpenoid saponin inhibiting LPS-stimulated expression of iNOS, COX-2, and NF-κB.		Others
TN2091	Polygalacin D		Apoptosis , IAP
	Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-induced iNOS and COX-2 protein and mRNA without an appreciable cytotoxi...		Apoptosis , IAP
T4951	Kauran-16,17-diol		Apoptosis , Others
	Kauran-16,17-diol, a natural diterpenoid product, exhibits anti-tumoral and apoptosis-inducing activities by inhibiting NO production in LPS-induced RAW 264.7 cells with an IC50 value of 17 μM.		Apoptosis , Others
T5764	Alliin	(S)-3-(Allylsulphinyl)-L-alanine	NF-κB , PPAR
	Alliin ((S)-3-(Allylsulphinyl)-L-alanine) is a garlic organosulfur compound that possesses various pharmacological properties.alliin protected against LPS-induced ALI by activating PPARγ, which subsequently inhibited LPS...		NF-κB , PPAR
T5S1989	Apiin	Apioside	Others
	1. Apiin (Apioside) is the reducing and stabilizing agent. 2. Apiin has inhibitory activity in-vitro on iNOS expression and nitrite production when added before LPS stimulation in the medium of J774.A1 cells.		Others
T3826	Polygalasaponin F		NF-κB , TLR , Akt , PI3K
	Polygalasaponin F has anti-neuroinflammatory activity, can inhibit the release of inflammatory cytokines TNF-α and NO induced by lipopolysaccharides (LPS) and reduce the expression of inducible nitric oxide synthases. Po...		NF-κB , TLR , Akt , PI3K
T3893	Forsythoside B		TNF , NF-κB
	Forsythoside B binds to LPS and reduces the biological activity of serum LPS, and inhibits NF-κB activation. Forsythoside B inhibits the inflammatory response and has antioxidant properties. Potent neuroprotective effect...		TNF , NF-κB
TN1949	Moracin C		ROS , NO Synthase
	Moracin C, a natural compound found in Morus mesozygia, Morus alba var. multicaulis, is an anti-inflammatory agent. moracin C inhibits nitric oxide (NO) release and LPS-activated reactive oxygen species (ROS) in cells.		ROS , NO Synthase
T6S0107	Peimine	Wanpeinine A,Dihydroisoimperialine,Verticine	Others
	1. Peimine (Wanpeinine A) has good anti-inflammatory effects in vivo. 2. Peimine is an inhibitor to inhibit LPS-induced production of inflammatory cytokines by blocking the MAPKs and NF-κB signaling pathway.		Others
T4S1616	Sanggenon D	Sanggenone D	NOS , COX , GABA Receptor
	Sanggenone D represents a new scaffold of positive GABAA receptor modulators, it also inhibits COX-2 activity (IC 50 = 73-100 μM). Sanggenone D has anti-inflammatory activity, it can inhibit NO production from lipopolysa...		NOS , COX , GABA Receptor
T3926	Echinatin	Retrochalcone	Free radical scavengers
	Echinatin (Retrochalcone) disturb the mitochondrial energy transfer reactions and membrane permeability, at a low concentration cause deterioration of respiratory control and oxidative phosphorylation of isolated rat liv...		Free radical scavengers
TN7235	4-methoxylonchocarpin		TNF , NF-κB
	4-methoxylonchocarpin was isolated from the roots of Abrus precatorius as a potent anti-inflammatory compound. 4-methoxylonchocarpin inhibited NF-κB-activated TNF expression by inhibiting the binding of LPS to TLR4 in ma...		TNF , NF-κB
T3S1692	Octahydrocurcumin		Anti-infection , NF-κB , Reactive Oxygen Species , ROS
	Octahydrocurcumin has antioxidant and and anti-inflammatory activities, it can inhibit the lipopolysaccharide (LPS)-induced inflammatory response via the mechanism of inhibiting NF-kB translocation to the nucleus. Octahy...		Anti-infection , NF-κB , Reactive Oxygen Species , ROS
T5660	Menthone		IL Receptor , TNF , NF-κB , Parasite
	Menthone has anti-inflammary activity,, it can suppress the lipopolysaccharide (LPS)-induced proinflammatory cytokines, interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha (TNF-alpha),as well as nuclear factor k...		IL Receptor , TNF , NF-κB , Parasite
TN1828	Kahweol		Apoptosis , NF-κB , AMPK
	Kahweol has anticarcinogenic, anti-angiogenic,and anti-inflammatory activities, it can block the LPS-induced activation of NF-kappaB by preventing IkappaB degradation and inhibiting IkappaB kinase activity.		Apoptosis , NF-κB , AMPK
T5773	Moslosooflavone	5-hydroxy-7,8-dimethoxyflavone	NF-κB , Reactive Oxygen Species
	Moslosooflavone (5-hydroxy-7,8-dimethoxyflavone) has anti-hypoxia activity, it can significantly prolong the survival time of hypoxic mice. 5-hydroxy-7,8-dimethoxyflavone significantly inhibits the transcriptional activi...		NF-κB , Reactive Oxygen Species
T3877	Esculentoside A		NF-κB , COX
	Esculentoside A can suppress inflammatory responses in LPS-induced ALI through inhibition of the NF-κB and mitogen-activated protein kinase signaling pathways. Esculentoside A may be useful for the treatment of autoimmun...		NF-κB , COX
T5814	Aurantiamide	TMC-58B	p38 MAPK , NF-κB
	Aurantiamide has anti-cancer, anti-inflammatory and antinociceptive activities, it may suppress the growth of malignant gliomas by blocking autophagic flux.Aurantiamide has an anti-neuroinflammatory effect on LPS stimula...		p38 MAPK , NF-κB
TN6985	Anhydronotoptol	4-{[(2E,5E)-3,7-dimethylocta-2,5,7-trien-1-yl]oxy}-7H-furo[3,2-g]chromen-7-one	NO Synthase
	Anhydronotoptol (4-{[(2E,5E)-3,7-dimethylocta-2,5,7-trien-1-yl]oxy}-7H-furo[3,2-g]chromen-7-one), a natural compound extracted from the umbelliferae plant Qiangwu, is a potent inhibitor of nitric oxide production, inhibi...		NO Synthase
TN1879	Lucideric acid A	Lucidenic acid A	MMP , p38 MAPK , JNK
	Lucideric acid A (Lucidenic acid A) is a modulator of JNK and p38 and enhances LPS-induced immune responses in monocytic THP-1 cells possibly via the modulation of p38 and JNK/MAPKs activation.		MMP , p38 MAPK , JNK
T3914	Saikosaponin C		Beta Amyloid , Caspase
	Saikosaponin C efficiently inhibited LPS-induced apoptotic cell death via inhibition of caspase-3 activation and caspase-3-mediated-FAK degradation.		Beta Amyloid , Caspase
TN1134	Euscaphic acid		Apoptosis , LDL , PI3K , DNA/RNA Synthesis , NO Synthase , Prostaglandin Receptor
	Euscaphic acid has anti-diabetic, and anti-inflammatory activities, it inhibits LPS-induced inflammatory responses by interference with the clustering of TRAF6 with IRAK1 and TAK1, resulting in blocking the activation of...
TN6694	5,6-Benzoflavone	β-Naphthoflavone,beta-NF	Antioxidant
	5,6-Benzoflavone (β-Naphthoflavone) is an exogenous ligand for the aryl hydrocarbon receptor, which disrupts zinc homeostasis in human hepatocellular carcinoma HepG2 cells. 5,6-Benzoflavone (β-Naphthoflavone) possesses a...		Antioxidant
TN1787	Isomucronulatol 7-O-glucoside	Isomucronulatol 7-O-beta-glucoside	Others
	Isomucronulatol 7-O-glucoside is a natural product		Others
T5S0167	Atractylenolide I		IL Receptor , TNF , TLR , JAK , STAT
	1. Atractylenolide-I has an anti-inflammatory effect by inhibiting TNF-α and IL-6 production; ameliorates sepsis syndrome, liver and kidney functions by reduction of pro-inflammatory cytokines and LPS. 2. Atractylenolide...		IL Receptor , TNF , TLR , JAK , STAT
T5S2059	Glaucine		Calcium Channel , Dopamine Receptor , Influenza Virus , Adrenergic Receptor , PDE
	Glaucine has antitussive, antioxidative potential and antiviral activities, it may be an anti-arthritic agent, it can enhance LPS and zymosan-induced IL-10 production. Glaucine can inhibit the migration and invasion of h...
T5727	CAFESTOL		ERK , NF-κB , COX , PGE Synthase
	CAFESTOL is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells. Cafestol has strong inhibitory activity on PGE2 production...		ERK , NF-κB , COX , PGE Synthase
T6S1665	Irisflorentin		Others , NO Synthase
	1. Irisflorentin blocks apoptosis pathways, by exerting its effects by promoting rpn-3 expression to enhance the activity of proteasomes and down-regulating egl-1 expression. 2. Irisflorentin has anti-inflammatory mechan...		Others , NO Synthase
TL0007	Bisdemethoxycurcumin	Curcumin III,Didemethoxycurcumin	Epigenetic Reader Domain , Wnt/beta-catenin
	Bisdemethoxycurcumin (Curcumin III) is a natural demethoxy derivative of curcumin. It is a potent activator of macrophage phagocytosis, interacting with 1α, 25-dihydroxy vitamin D3 to stimulate amyloid-β clearance by mac...		Epigenetic Reader Domain , Wnt/beta-catenin
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天然物製品

Lipopolysaccharides, Escherichiacoli (11C)

T41078

Synonym: LPS E. coli O55:B5,Lipopolysaccharide, E. coli O111:B4

Target: ERK, p38 MAPK, NF-κB

Deoxyandrographolide

TQ0218

Synonym: 14-deoxyandrographolide

Target: IL Receptor, TNF

TOMATIDINE HYDROCHLORIDE

T4592

Synonym: Tomatidine,Tomatidine HCl

Target: Others, NF-κB, JNK, Autophagy

(-)-Epigallocatechin Gallate

T2988

Synonym: Epigallocatechol Gallate,EGCG

Target: Ferroptosis, Reactive Oxygen Species, HIV Protease, Mitochondrial Metabolism, Endogenous Metabolite, Autophagy

2'-FUCOSYLLACTOSE

TN6796

Synonym: 2'-Fucosyl-D-lactose

Synonym: FT-0626663,Tetraprenol,CJ24095,CJ 24095,FT0626663,CJ-24095

Target: Apoptosis

2,5-Dihydroxyacetophenone

TCS2170

Synonym: Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP

Target: ERK, NF-κB, Tyrosinase

Physalin L

TN1102

Synonym:

Target: Others, NO Synthase

Kaempferol 3-O-β-D-glucuronide

TN1818

Synonym: Kaempferol-3-O-glucuronide,Kaempferol-3-beta-O-glucuronide,Kaempferol-3-glucuronide

Target: IL Receptor

Deacetylpseudolaric acid A

8-Hydroxy-5-O-beta-D-glucopyranosylpsoralen

TN3281

Synonym:

Target: Others

7-O-Primverosylpseudobaptigenin

T83239

Synonym:

Target:

11-O-Methylpseurotin A

T62625

Synonym:

Target:

20-Hydroxyganoderic acid G

Target: Others, NF-κB, COX, Antibacterial

Desmethoxyyangonin

T5S0734

Synonym: Desmethoxy yangonin,Demethoxyyangonin,5,6-Dehydrokavain

Target: Others, Monoamine Oxidase

Deacetyl ganoderic acid F

Synonym: Hederagenic acid,Astrantiagenin E,Caulosapogenin,Hederagenol

Target: Apoptosis, IAP

kauran-16,17-diol

T4951

Synonym:

Target: Apoptosis, Others

Alliin

T5764

Synonym: (S)-3-(Allylsulphinyl)-L-alanine

Target: NF-κB, TLR, Akt, PI3K

Target: ROS, NO Synthase

Peimine

T6S0107

Synonym: Wanpeinine A,Dihydroisoimperialine,Verticine

Target: Others

Sanggenon D

T4S1616

Synonym: Sanggenone D

Target: NOS, COX, GABA Receptor

Echinatin

T3926

Synonym: Retrochalcone

Target: Free radical scavengers

4-methoxylonchocarpin

Target: Anti-infection, NF-κB, Reactive Oxygen Species, ROS

Menthone

T5660

Synonym:

Target: IL Receptor, TNF, NF-κB, Parasite

Kahweol

TN1828

Synonym:

Target: Apoptosis, NF-κB, AMPK

Moslosooflavone

T5773

Synonym: 5-hydroxy-7,8-dimethoxyflavone

Target: NF-κB, Reactive Oxygen Species

Target: p38 MAPK, NF-κB

Anhydronotoptol

TN6985

Synonym: 4-{[(2E,5E)-3,7-dimethylocta-2,5,7-trien-1-yl]oxy}-7H-furo[3,2-g]chromen-7-one

Target: NO Synthase

Lucideric acid A

TN1879

Synonym: Lucidenic acid A

Target: MMP, p38 MAPK, JNK

Saikosaponin C

T3914

Synonym:

Target: Beta Amyloid, Caspase

Euscaphic acid

TN1134

Synonym:

Target: Apoptosis, LDL, PI3K, DNA/RNA Synthesis, NO Synthase, Prostaglandin Receptor

5,6-Benzoflavone

TN6694

Synonym: β-Naphthoflavone,beta-NF

Target: Antioxidant

Isomucronulatol 7-O-glucoside

TN1787

Synonym: Isomucronulatol 7-O-beta-glucoside

Target: IL Receptor, TNF, TLR, JAK, STAT

Glaucine

T5S2059

Synonym:

Target: Calcium Channel, Dopamine Receptor, Influenza Virus, Adrenergic Receptor, PDE

CAFESTOL

T5727

Synonym:

Target: ERK, NF-κB, COX, PGE Synthase

Irisflorentin

T6S1665

Synonym:

Target: Others, NO Synthase

Bisdemethoxycurcumin

TL0007

Synonym: Curcumin III,Didemethoxycurcumin

Target: Epigenetic Reader Domain, Wnt/beta-catenin

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-00966	GDF-5 Protein, Human, Recombinant	Human	E. coli
	Growth Differentiation Factor 5(GDF-5, BMP-14) is a member of the BMP family of TGFβ superfamily proteins. Human GDF-5, -6, and -7 are a defined subgroup of the BMP family. GDF-5 is synthesized as a homodimeric precursor...
TMPH-03765	Virus-Like Particles (VLPs) isotype control

TMPY-02846	CLPS Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Colipase belongs to the colipase family. Structural studies of the complex and of colipase alone have revealed the functionality of its architecture. It is a small protein with five conserved disulphide bonds. Structural...
TMPH-00581	ATP-dependent Clp protease adapter protein ClpS Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
TMPY-00084	CLPS Protein, Rat, Recombinant (His)	Rat	HEK293
	Colipase belongs to the colipase family. Structural studies of the complex and of colipase alone have revealed the functionality of its architecture. It is a small protein with five conserved disulphide bonds. Structural...
TMPY-02904	TLR4 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	TLR4, also known as TLR-4, is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans...
TMPY-01825	RP105/CD180 Protein, Human, Recombinant (His)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-01774	TREM-1 Protein, Human, Recombinant (His)	Human	HEK293
	TREM1 (triggering receptor expressed on myeloid cells) is a type I transmembrane protein with a single Ig-like domain, and is selectively expressed on blood neutrophils and a subset of monocytes. As a member of the growi...
TMPY-04957	PD-L2 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ...
TMPY-04346	PD-L2 Protein, Human, Recombinant (His)	Human	HEK293
	Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ...
TMPY-05827	PD-L2 Protein, Human, Recombinant (mFc)	Human	HEK293
	Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ...
TMPY-05053	ANGPTL2 Protein, Human, Recombinant (His)	Human	HEK293
	The angiopoietin-like protein (ANGPTL) family is homologous to angiopoietins but does not bind to the Tie2 receptor. The function of ANGPTLs has been elucidated largely in the context of angiogenesis and lipid metabolism...
TMPY-02698	CD14 Protein, Human, Recombinant (His)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-01047	IL-1R1 Protein, Human, Recombinant (hFc)	Human	HEK293
	Interleukin 1 receptor, type I (IL-1R1) also known as CD121a (Cluster of Differentiation 121a), is an interleukin receptor. IL-1R1/CD121a is a cytokine receptor that belongs to the interleukin 1 receptor family. This pro...
TMPY-01357	S100A9 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that...
TMPY-00754	IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99)	Human	HEK293
	Interleukin 8 (IL-8), also known as CXCL8, which is a chemokine with a defining CXC amino acid motif that was initially characterized for its leukocyte chemotactic activity, is now known to possess tumorigenic and proang...
TMPY-04726	IL-8/CXCL8 Protein, Human, Recombinant (His)	Human	Yeast
	Interleukin 8 (IL-8), also known as CXCL8, which is a chemokine with a defining CXC amino acid motif that was initially characterized for its leukocyte chemotactic activity, is now known to possess tumorigenic and proang...
TMPY-00472	IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99)	Human	E. coli
	Interleukin 8 (IL-8), also known as CXCL8, which is a chemokine with a defining CXC amino acid motif that was initially characterized for its leukocyte chemotactic activity, is now known to possess tumorigenic and proang...
TMPH-00650	LptE Protein, E. coli, Recombinant (His & Myc)	E. coli	E. coli
	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer...
TMPH-00649	LptA Protein, E. coli, Recombinant (His & SUMO)	E. coli	E. coli
	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interact...
TMPH-00648	LapB Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of prote...
TMPH-01058	Cathelicidin antimicrobial peptide Protein, Human, Recombinant (His & Myc & SUMO)	Human	E. coli
	Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity.
TMPH-03069	CSL3 Protein, Oncorhynchus keta, Recombinant (His)	Oncorhynchus keta	E. coli
	L-rhamnose binding lectin. Has hemagglutinating activity towards rabbit erythrocytes, human type A erythrocytes, human type B erythrocytes, human type O erythrocytes and sheep erythrocytes. Hemagglutinating activity is i...
TMPK-00596	SECTM1 Protein, Human, Recombinant (hFc)	Human	HEK293
	SECTM1 is a T/NK cell "co-stimulatory" molecule that is expressed in the peripheral blood by neutrophils and monocytes.Human monocytic cells also displayed a pronounced negative regulation of SECTM1 mRNA expression by LP...
TMPH-01083	CHID1 Protein, Human, Recombinant (His)	Human	E. coli
	Saccharide- and LPS-binding protein with possible roles in pathogen sensing and endotoxin neutralization. Ligand-binding specificity relates to the length of the oligosaccharides, with preference for chitotetraose (in vi...
TMPH-02577	CHID1 Protein, Mouse, Recombinant (His & Myc)	Mouse	HEK293
	Saccharide- and LPS-binding protein with possible roles in pathogen sensing and endotoxin neutralization. Ligand-binding specificity relates to the length of the oligosaccharides, with preference for chitotetraose (in vi...
TMPK-01242	MD2/LY96 Protein, Human, Recombinant (His)	Human	E. coli
	MD2, a 160-residue accessory glycoprotein, is responsible for the recognition and binding of Gram-negative bacterial membrane component, lipopolysaccharide (LPS).Internalization of pathogen inside the mononuclear phagocy...
TMPY-01569	CD5L Protein, Human, Recombinant (His)	Human	HEK293
	CD5L, also known as CD5 antigen-like, is a soluble protein belonging to group B of the scavenger receptor cysteine-rich (SRCR) superfamily and contains three SRCR domains. It is a secreted glycoprotein and expressed by m...
TMPY-00714	CD5L Protein, Mouse, Recombinant (His)	Mouse	HEK293
	CD5L, also known as CD5 antigen-like, is a soluble protein belonging to group B of the scavenger receptor cysteine-rich (SRCR) superfamily and contains three SRCR domains. It is a secreted glycoprotein and expressed by m...
TMPY-03999	MD2/LY96 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	LY96 (Lymphocyte Antigen 96, also known as ESOP-1) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes a protein that associates with toll-like receptor 4 on the cell su...
TMPK-00632	MD2/LY96 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	E. coli
	MD2, a 160-residue accessory glycoprotein, is responsible for the recognition and binding of Gram-negative bacterial membrane component, lipopolysaccharide (LPS).Internalization of pathogen inside the mononuclear phagocy...
TMPY-05528	Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx), Biotinylated	Human	E. coli
	Apolipoprotein E (ApoE) is a 34.2 kDa glycosylated protein with 299 amino acid residues. There are three isoforms in human (apoE2, apoE3, and apoE4) due to different amino acid residues at positions 112 and 158. ApoE is ...
TMPK-00767	SLPI Protein, Human, Recombinant (hFc)	Human	HEK293
	Elafin and SLPI (secretory leucocyte protease inhibitor) have multiple important roles both in normal homoeostasis and at sites of inflammation. These include antiprotease and antimicrobial activity as well as modulation...
TMPY-05297	Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx)	Human	E. coli
	Apolipoprotein E (ApoE) is a 34.2 kDa glycosylated protein with 299 amino acid residues. There are three isoforms in human (apoE2, apoE3, and apoE4) due to different amino acid residues at positions 112 and 158. ApoE is ...
TMPJ-00527	SP-D Protein, Human, Recombinant (His)	Human	Human Cells
	Surfactant Pulmonary-Associated Protein D (SP-D) is a 43 kDa member of the collectin family of innate immune modulators. Its principal components consist of a collagen-like region and a C-terminal carbohydrate recognitio...
TMPK-00924	SLPI Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Elafin and SLPI (secretory leucocyte protease inhibitor) have multiple important roles both in normal homoeostasis and at sites of inflammation. These include antiprotease and antimicrobial activity as well as modulation...
TMPY-01667	RP105/CD180 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-06527	TREM-1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	TREM1 (triggering receptor expressed on myeloid cells) is a type I transmembrane protein with a single Ig-like domain, and is selectively expressed on blood neutrophils and a subset of monocytes. As a member of the growi...
TMPH-02828	PLAA Protein, Mouse, Recombinant (His & Myc)	Mouse	Baculovirus
	Plays a role in protein ubiquitination, sorting and degradation through its association with VCP. Involved in ubiquitin-mediated membrane proteins trafficking to late endosomes in an ESCRT-dependent manner, and hence pla...
TMPK-00567	VSIG4 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	VSIG4, a B7 family-related protein, is a negative regulator of T cell activation.T cell activation by APCs is positively and negatively regulated by members of the B7 family. Unlike that of B7 family members, surface exp...
TMPY-01666	RP105/CD180 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-00943	TREM-1 Protein, Human, Recombinant (His & hFc)	Human	HEK293
	TREM1 (triggering receptor expressed on myeloid cells) is a type I transmembrane protein with a single Ig-like domain, and is selectively expressed on blood neutrophils and a subset of monocytes. As a member of the growi...
TMPY-02436	PD-L2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ...
TMPY-02352	PD-L2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ...
TMPY-00120	PD-L2 Protein, Human, Recombinant (hFc)	Human	HEK293
	Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ...
TMPY-05613	PD-L2 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ...
TMPY-03738	PD-L2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ...
TMPY-04223	PD-L2 Protein, Rat, Recombinant (hFc)	Rat	HEK293
	Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ...
TMPY-04225	PD-L2 Protein, Rat, Recombinant (His)	Rat	HEK293
	Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ...
TMPY-06819	PD-L2 Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293
	Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ...
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