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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T41277 | PACMA 31 | Others | |
PACMA 31 is an irreversible and covalent inhibitor of protein disulfide isomerase (PDI) with an IC50 of 10 μM. PACMA 31 significantly suppresses ovarian tumor growth and exhibits tumor targeting ability. | |||
T9880 | ZINC05007751 | MAPK | |
ZINC05007751 is an effective inhibitor of NIMA-related kinase NEK6 (IC50 = 3.4 μM). ZINC05007751 is very selective against NEK1 and NEK6 with no significant activity observed against NEK2, NEK7, and NEK9. | |||
T3713 | BAY-876 | transporter | |
BAY-876 is an orally active and selective inhibitor of glucose transporter 1 (GLUT1, IC50= 2 nM). BAY-876 exhibits >130-fold more selective for GLUT1 than GLUT2, GLUT3, and GLUT4. BAY-876 also inhibits glycolytic metabol... | |||
T8464 | RA-9 | Apoptosis , DUB | |
RA-9 is a potent and selective proteasome-associated inhibitor of deubiquitinating enzymes (DUBs), with favorable toxicity profile and anticancer activity. RA-9 selectively induces apoptosis in ovarian cancer cell lines. | |||
T3102 | NS-1619 | Apoptosis , Potassium Channel | |
NS1619 have cardio-protective effects after ischemia-reperfusion injury. | |||
T1841 | UNC0379 | Histone Methyltransferase | |
UNC0379 is a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8. | |||
T24557 | NSC756093 | NSC-756093,NSC 756093 | Others |
NSC756093 potentially inhibits GBP1:PIM1 interaction. NSC756093 can be used in ovarian cancer studies. | |||
T3082 | SGC0946 | Histone Methyltransferase | |
SGC0946 is a highly effective and specific DOT1L methyltransferase inhibitor (IC50: 0.3 nM); selectively kill mixed lineage leukemia cells. | |||
T9698 | UC2288 | Mdm2 , p53 | |
UC2288 is a relatively selective p21 attenuator which is synthesized based Sorafenib. UC2288 attenuates p21 protein levels with minimal effect on p21 protein stability. | |||
T6207 | SC144 | Apoptosis , Interleukin | |
SC144 is an orally active small-molecule gp130 inhibitor. | |||
T12695 | RBN-2397 | PARP | |
RBN-2397 is a potent, selective and orally active accross species NAD+ competitive PARP7 inhibitor with IC50 less than 3 nM. | |||
T9497 | Niraparib tosylate monohyrate | PARP | |
Niraparib, also know as MK-4827, is an inhibitor of poly (ADP-ribose) polymerase (PARP) with potential antineoplastic activity. MK4827 inhibits PARP activity, enhancing the accumulation of DNA strand breaks and promoting... | |||
T16522 | Phenoxodiol | Dehydroequol,Idronoxil,Haginin E | Apoptosis , IAP , Caspase , Topoisomerase , p53 |
Phenoxodiol (Idronoxil) activates the mitochondrial caspase system, inhibits X-linked inhibitor of apoptosis(XIAP), disrupts FLICE inhibitory protein(FLIP) expression, and sensitizes the cancer cells to Fas-mediated apop... | |||
T8930 | CID44216842 | KUC103479N-02 | CDK , Ras |
CID44216842 (KUC103479N-02) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT... | |||
T2463 | ML141 | CID-2950007 | Apoptosis , CDK , Ras |
ML141 (CID-2950007) is an effective, specific and reversible non-competitive inhibitor of Rho family GTPase cdc42 (IC50: 200 nM). | |||
T2679 | BMS-265246 | BMS265246 | CDK |
BMS-265246 is a potent and selective CDK1/2 inhibitor. | |||
T3231 | Niraparib | MK-4827 | Apoptosis , Others , PARP |
Niraparib (MK-4827) is a PARP inhibitor that selectively inhibits PARP1 and PARP2 (IC50=3.8/2.1 nM). Niraparib has antitumor activity, inhibits DNA damage repair, and induces apoptosis. | |||
T8806 | Fluzoparib | HS10160,SHR3162 | PARP |
Fluzoparib (SHR3162) is a novel, potent, and orally available inhibitor of PARP, potentially for the treatment of solid tumours. | |||
TP1929L1 | Saralasin acetate(34273-10-4 free base) | RAAS | |
Saralasin acetate is a Non-selective angiotensin II antagonist. | |||
T2617 | SNS-314 Mesylate | SNS-314 | Aurora Kinase |
SNS-314 Mesylate (SNS-314) is an effective and specific Aurora A/B/C inhibitor (IC50: 9/31/3 nM). It is less inhibition of Trk A/B, Fms, Flt4, c-Raf, Axl, and DDR2. | |||
T14871 | Carboxyamidotriazole Orotate | L-651582 Orotate,CAI Orotate | Calcium Channel |
Carboxyamidotriazole Orotate (L-651582 Orotate) is a cytostatic inhibitor of non-voltage-operated calcium channels and calcium channel-mediated signaling pathways. Carboxyamidotriazole Orotate (L-651582 Orotate) is the o... | |||
T3299 | Xevinapant hydrochloride | AT-406 HCl,SM-406 | Apoptosis , IAP |
Xevinapant hydrochloride (AT-406 HCl) , an orally active antagonist of multiple inhibitor of apoptosis proteins(IAP), inhibits progression of human ovarian Y binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.... | |||
T21412 | Ketorolac | Toradol,Sprix,Acuvail,Macril,Acular | COX |
Ketorolac (Acuvail) is a non-steroidal anti-inflammatory drug (NSAID) in the family of heterocyclic acetic acid derivatives. It acts by inhibiting the bodily synthesis of prostaglandins. | |||
T0334 | Rosiglitazone | BRL49653 | Ferroptosis , TRP/TRPV Channel , PPAR , Autophagy |
Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity. Rosiglitazone is also a hypoglycemic agent and a thiazolidinedione insulin sensitizer. | |||
T6763 | Xevinapant | ARRY-334543,SM-406,AT406,Debio-1143 | IAP |
Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, ... | |||
T0964 | Floxuridine | 5-Fluorouracil 2'-deoxyriboside,FUDR,Deoxyfluorouridine,NSC 27640 | Apoptosis , Nucleoside Antimetabolite/Analog , Others , DNA/RNA Synthesis , Antibacterial , HSV |
Floxuridine (FUDR) is an antimetabolite, floxuridine inhibits thymidylate synthase, resulting in disruption of DNA synthesis and cytotoxicity. | |||
T7313 | Enclomiphene citrate | Enclomifene citrate,(E)-Clomiphene citrate,trans-Clomiphene citrate | Estrogen Receptor/ERR |
Enclomiphene citrate (trans-Clomiphene citrate) is a non-steroidal estrogen receptor antagonist,with antioestrogenic property | |||
T4102 | Goserelin acetate | Fertilan,ICI-118630 acetate,Zoladex | Apoptosis , GNRH Receptor |
Goserelin acetate (Fertilan) is a synthetic long-acting agonist of gonadotropin-releasing hormone, used in treatments of cancer. | |||
T3353 | Niraparib hydrochloride | MK-4827 hydrochloride,MK-4827 (hydrochloride) | Apoptosis , Others , PARP |
Niraparib hydrochloride (MK-4827 hydrochloride) is an inhibitor of poly (ADP-ribose) polymerase (PARP) with potential antineoplastic activity. Niraparib hydrochloride inhibits PARP activity, enhancing the accumulation of... | |||
T6023 | Nutlin-3a | (-)-Nutlin-3,Nutlin-3a chiral,(−)-Nutlin-3 | Apoptosis , E1/E2/E3 Enzyme , Autophagy |
Nutlin-3a ((−)-Nutlin-3), the active enantiomer of Nutlin-3, inhibits MDM2-p53 interactions and stabilizes the p53 protein. | |||
T6646 | Rosiglitazone hydrochloride | BRL-49653 HCl,Rosiglitazone HCl | Ferroptosis , TRP/TRPV Channel , PPAR , Autophagy |
Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells. | |||
T6690 | T0901317 | Apoptosis , FXR , Liver X Receptor , ROR | |
T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively; it inhibits nuclear factor/κB (NF/κB). | |||
T1101 | Minocycline hydrochloride | Minocycline HCl | HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic |
Minocycline hydrochloride (Minocycline HCl) is a tetracycline antibiotic with excellent absorption and tissue penetration that is used for several bacterial infections as well as treatment of acne. Minocycline hydrochlor... | |||
T6892 | Niraparib tosylate | MK-4827 (tosylate),MK 4827 tosylate,Niraparib (MK-4827) tosylate | Apoptosis , PARP |
Niraparib tosylate (MK-4827 (tosylate))(with IC50 of 3.8 nM/2.1 nM) is a selective PARP1/PARP2 inhibitor. | |||
T2669 | Berzosertib | VX-970,VE-822 | ATM/ATR |
Berzosertib (VE-822) has been used in trials studying the treatment of Ovarian Neoplasms, Ovarian Serous Tumor, Adult Solid Neoplasm, Advanced Solid Tumor, and Advanced Solid Neoplasm, among others. | |||
T10395L | ATM-3507 | Myosin | |
ATM-3507 is a protomyosin inhibitor with anticancer activity that inhibits human melanoma and can be used to study ovarian cancer. | |||
T72046 | PF-17 | Others | |
PF-17 can be used as a PUF60 inhibitor for the treatment of ovarian cancer. | |||
T24997 | ABT-510 acetate | ABT 510 acetate | Apoptosis |
ABT-510 acetate is an endogenous anti-angiogenic TSP peptide inhibitor, a thrombospondin analog, with anti-inflammatory, anti-cancer and anti-angiogenic activity that induces apoptosis and inhibits ovarian tumor growth i... | |||
TP2051L | CTCE 9908 acetate | CXCR | |
CTCE 9908 acetate is an antagonist of CXCR4 and inhibits migration in CXCR4-expressing ovarian cancer cells. | |||
T68065 | Enloplatin | ||
Enloplatin is a carboplatin analog that has a partial role in advanced ovarian cancer. | |||
T17216 | Valspodar | PSC 833 | P-gp |
Valspodar (PSC 833) is a specific P-glycoprotein inhibitor and MDR regulator often used as a chemical sensitizer to study advanced epithelial ovarian cancer. | |||
T27454 | GSK2008607 | Raf | |
GSK2008607 is a potent B-RafV600E inhibitor with anticancer activity and can be used to study breast, colorectal, melanoma, thyroid, and ovarian cancers. | |||
T13783 | MT-4 | Others | |
MT-4 inhibits the adhesion of ovarian cancer (OC) cells to the peritoneum. | |||
T34262 | RAPTA-C | Apoptosis | |
RAPTA-C induces EAC cell cycle arrest and apoptosis via the mitochondrial and p53-JNK pathways, and can be used in the study of breast and ovarian cancer. | |||
T17159 | Treosulfan | NSC 39069,Treosulphan | DNA Alkylator/Crosslinker , DNA Alkylation |
Treosulfan (Treosulphan) is a bifunctional alkylating agent. It also has activity in ovarian cancer and other solid tumor types. | |||
T12238 | NNC 55-0396 | NNC 55-0396 dihydrochloride | Calcium Channel |
NNC 55-0396 is a highly selective blocker of T-type calcium channel with IC50 of 6.8 μM. NNC 55-0396 can be used in studies about preventing human ovarian cancer cell proliferation. | |||
T38410 | Phosphoramide mustard | DNA Alkylation , Drug Metabolite | |
Phosphoramide mustard is a toxic metabolite of cyclophosphamide with anticancer activity and ovarian toxicity that induces DNA damage. | |||
T14510 | BAY-850 | Epigenetic Reader Domain | |
BAY-850 is a selective and potent inhibitor of adenosine triphosphatase family protein 2 (ATAD2) (IC50: 166 nM) that inhibits ovarian cancer growth and metastasis in in vitro and in vivo models. | |||
TP1434L | Lecirelin acetate(61012-19-9 free base) | GNRH Receptor | |
Lecirelin acetate is a synthetic GnRH (gonadotropin releasing hormone) analogue which shows a great efficacy in the treatment of bovine ovarian follicular cysts. | |||
TP1425 | Motilin (26-47), human, porcine | Motilin Receptor | |
Motilin (26-47), human and pig are endogenous Motilin receptor ligands in Chinese hamster ovarian cell lines, with Ki and EC50 at 2.3 nM and 0.3 nM, respectively. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T8206 | Cycleanine | Others | |
Cycleanine has potent antibacterial, antifungal, antiplasmodial, and cytotoxic activities. | |||
T5755 | Aloesin | Tyrosinase | |
Aloesin is a C-glycosylated chromone compound found in aloe (Liliaceae) that inhibits tyrosinase (IC50 = 0.9 mM), an enzyme responsible for catalyzing the first step of the conversion of tyrosine to melanin. | |||
TN1839 | Kumatakenin | Jaranol,Kaempferol 3,7-O-dimethyl ether | Apoptosis , Anti-infection |
Kumatakenin can suppress >80% of the SOS-inducing activity of Trp-P-1 at <0.06 micromol/mL. | |||
T5S1882 | Songorine | Napellonine,Zongorine,Bullatine G | Others , GABA Receptor |
Songorine (Napellonine) shows favorable anti-tumor activity in preliminary pharmacological verification trials including cell proliferation and molecular docking assays. | |||
T14001 | 11-Beta-hydroxyandrostenedione | NSC-17102,4-Androsten-11β-ol-3,17-dione | Endogenous Metabolite |
11-Beta-hydroxyandrostenedione (NSC-17102) is a steroid mainly found in the adrenal origin (11β-hydroxylase is present in adrenal tissue, but absent in ovarian tissue), which is a 11β-hydroxysteroid dehydrogenase isozyme... | |||
TN2064 | Physcion 8-O-β-D-glucopyranoside | Physcion 8-O-beta-D-monoglucoside | TNF |
Physcion 8-O-β-D-glucopyranoside (Physcion 8-O-beta-D-monoglucoside) has anti-inflammatory and anti-cancer activities. Physcion 8-O-β-D-glucopyranoside can be used in studies about common malignancy cancer. | |||
T34394 | Rotenolone | Rotenolone I,12alpha-HYDROXYROTENONE | Others |
Rotenolone (12alpha-HYDROXYROTENONE) is a metabolite of Rotenone which is a natural compound derived from plants of the genera Derris and Lonchocarpus. | |||
T1174 | Topotecan hydrochloride | SKF 104864A,SKFS 104864A,NSC609699,Nogitecan HCl,NSC 609669,Topotecan HCl | Apoptosis , Topoisomerase , Autophagy |
Topotecan hydrochloride (NSC609699) is an antineoplastic agent used to treat ovarian cancer. | |||
T3S1265 | Liriopesides B | Nolinospiroside F | Others |
Liriopesides B (Nolinospiroside F) exhibited potential anticancer activity against human ovarian cancer A2780 cells. | |||
T5784 | Topotecan | NSC 609669,SKF 104864A | Topoisomerase , Autophagy |
Topotecan (NSC-609669) is a Topoisomerase I inhibitor,and is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases. | |||
T21883 | Gedunin | HSP | |
Gedunin is an important limonoid present in several genera of the Meliaceae family, mainly in seeds. Gedunin is an Hsp90 inhibitor, and inhibits ovarian cancer cell proliferation. | |||
T5780 | HYPOCRELLIN B | Apoptosis , Parasite , Antifungal | |
HYPOCRELLIN B are photosensitive pigments isolated from Hypocrella bambusae Sacc. Hypocrellin B causes DNA strand breakage, induces apoptosis in ovarian cancer cells, and inhibits proliferation of Staphylococcus by incre... | |||
T35749 | Thymohydroquinone | Thymoquinol | Antioxidant , Reactive Oxygen Species |
Thymohydroquinone (Thymoquinol) is a monoterpenoid phenolic compound found in thyme, oregano, and other plants in the labiaceae family. Thymohydroquinone inhibits cancer cell growth, reduces oxidative stress and modulate... | |||
T4S0998 | Trifolirhizin | TNF , Tyrosinase | |
Trifolirhizin exerts varying degrees of inhibition on tyrosinase-dependent melanin biosynthesis, and therefore, are candidates as skin-whitening agents.Trifolirhizin possesses potential anti-inflammatory and anti-cancer ... | |||
T17155 | Trabectedin | Ecteinascidin 743,ET-743 | Apoptosis , Reactive Oxygen Species |
Trabectedin (Ecteinascidin 743) has potent antitumor activity and the potential for soft tissue sarcoma and ovarian cancer research. Trabectedin inhibits cell growth of MX-1, MCF7 and MCF7/DXR cells with IC50 values of 0... | |||
T3923 | Calycosin | Cyclosin,3'-Hydroxyformononetin | Apoptosis , Tyrosinase |
Calycosin (Cyclosin) acts as a selective estrogen receptor modulator. Calycosin induces apoptosis in human ovarian cancer SKOV3 cells by activating caspases and Bcl-2 family proteins. Calycosin suppresses breast cancer c... | |||
T3673 | Mollugin | Rubimaillin | HER , JAK |
Mollugin (Rubimaillin) may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upr... | |||
TN4341 | IVHD-valtrate | Mdm2 , BCL , PARP , Caspase , p53 | |
VHD-valtrate has anticancer effects against human ovarian cancer cells in vitro and in vivo, it is a potential therapeutic agent for ovarian cancer, providing a basis for development of the compound as a novel chemothera... | |||
T38698 | Cathayanon H | ||
Cathayanon H, a compound derived from the paper mulberry tree, exhibits cytotoxicity against human ovarian carcinoma cells. | |||
TN4154 | Gomisin L1 | Others | |
(-)-Gomisin L1 induces G2/M arrest and apoptosis in human ovarian cancer cells. | |||
TN5156 | Totaradiol | NADPH-oxidase | |
Totaradiol shows antioxidant activity, it can inhibit linoleic acid autoxidation but not generation of superoxide anion. Totaradiol exhibits cytotoxic activity against the A2780 ovarian cancer cell line. | |||
TN2229 | Soyasaponin Ac | Others | |
Soyasaponin Ac can decrease the drug resistance via EMT pathway and weaken the migration ability of ovarian cancer cells. | |||
TN3383 | α-Amyrin palmitate | alpha-Amyrin palmitate | PKA |
alpha-Amyrin palmitate is antiarthritic in the adjuvant model of arthritis in rats. alpha-Amyrin palmitate is a potent non-competitive inhibitor of chymotrypsin (Ki=6 microM), it also shows weak cytotoxicity against the ... | |||
T36893 | 4-oxo Withaferin A | ||
4-oxo Withaferin A is a derivative of the steroidal lactone withaferin A that has anticancer activity.1 It is cytotoxic to A2780 ovarian cancer cells and carboplatin-resistant A2780 (A2780/CP70) cells (IC50s = 7.3 and <1... | |||
TN2913 | 3-Acetoxy-11-ursen-28,13-olide | Phosphatase | |
3β-Acetoxy-urs-11-en-28,13-olide exhibits significant protein tyrosine phosphatase 1B (PTP1B) inhibitory activity, it is a mixed-type PTP1B inhibitor. It exhibits weak-moderate antiproliferative activity against the A278... | |||
TN3447 | Arjunglucoside I | ||
Arjunglucoside I has anti-inflammatory activity, it exhibits significant activity against carrageenan-induced paw edema in rat. It also shows antiproliferative activity against the A2780 human ovarian cancer cell line wi... | |||
T35647 | 4-oxo-27-TBDMS Withaferin A | ||
4-oxo-27-TBDMS Withaferin A is a derivative of the steroidal lactone withaferin A that has anticancer activity.1 It is cytotoxic to A2780 ovarian cancer cells (IC50 = 17 μM) but not to carboplatin-resistant A2780 (A2780/... | |||
T82273 | Gochnatiolide A | ||
Gochnatiolide A, a dimeric sesquiterpene isolated from Ainsliaea henryi, demonstrates antiproliferative properties against various cell lines, including kidney, melanoma, ovarian-resistant, and glioma [1] [2]. | |||
T83762 | Lentztrehalose C | ||
Lentztrehalose C, a disaccharide identified in Lentzea, exhibits autophagy-inducing activity. It effectively induces autophagy in MeWo melanoma and OVK18 ovarian cancer cells at a concentration of 100 mM. | |||
TN2529 | 1-Decarboxy-3-oxo-ceanothic acid | DNA/RNA Synthesis | |
1-Decarboxy-3-oxo-ceanothic acid shows in vitro cytotoxic activity in a human ovarian adenocarcinoma cell line, the cytotoxic effect is mediated, at least in part, by the induction of apoptosis. It shows cytotoxic agains... | |||
T73681 | Aspidin BB | ||
Aspidin BB, a phloroglucinol derivative isolated from the aerial part of Dryopteris championii, exhibits anticancer activity. It induces cell cycle arrest and apoptosis in human ovarian HO-8910 cells [1] [2]. | |||
T37552 | (+)-Macrosphelide A | ||
(+)-Macrosphelide A is a fungal metabolite originally isolated from Microsphaeropsis. It inhibits adhesion of HL-60 human leukemia cells to human umbilical vein endothelial cells (HUVECs) in a concentration-dependent man... | |||
TN2936 | 3-Hydroxy-11-ursen-28,13-olide | Others | |
3β-Hydroxy-urs-11-en-28,13β-olide shows a potent concentration-independent cytoprotective effect against CCl4-induced injury on human hepatoma cell line relative to silymarin as a reference standard. It exhibits weak-mod... | |||
TN4168 | Grifolin | Others | |
Grifolin has anti-cancer effects, it induces apoptosis and promotes cell cycle arrest in the A2780 human ovarian cancer cell line via inactivation of the ERK1/2 and Akt pathways; it enhances the differentiation and proli... | |||
T38250 | L-Sepiapterin | ||
L-Sepiapterin, also known as Sepiapterin, is a precursor compound crucial for the production of tetrahydrobiopterin (BH4), which serves as a coenzyme for endothelial nitric oxide synthase (eNOS). This compound demonstrat... | |||
TN6524 | Irilone | ||
Irilone has immunomodulatory, and α-amylase inhibitory activities, it exhibits the selective inhibition toward CYP3 A4 rather than other major human CYPs. Irilone exhibited prominent antioxidant activities with the IC50 ... | |||
TN5474 | Bonducellin | ||
Bonducellin has anti-inflammatory activities, it can significantly and dose-dependently inhibit the inflammatory mediators; nitric oxide (NO), and cytokines [tumor necrosis factor (TNF)-alpha and interleukin (IL)-12. Bon... | |||
T35409 | (+)-δ-Cadinene | Apoptosis , Antibacterial | |
(+)-δ-Cadinene is a sesquiterpene from G. hirsutum with antibacterial, insecticidal, anticancer and antiproliferative activities. It showed a MIC value of 31.25 μg/ml against S. pneumoniae and LC50s values of 8.23, 9. 2 ... | |||
TN3364 | Agrimonolide | Apoptosis , Dehydrogenase , p38 MAPK , ROS , JAK | |
Agrimonolide, a compound derived from isocoumarins and found mainly in the herb Agrimonia pilosa Ledeb, has significant biological activity. agrimonolide exerts anti-inflammatory effects by inhibiting lipopolysaccharide ... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPJ-00147 | FOLR1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
FOLR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-75 kDa and the accession number is P15328. | |||
TMPJ-01432 | CA125/MUC16 Protein, Human, Recombinant (hFc & AVI), Biotinylated | Human | HEK293 Cells |
MUC16, also known as the CA125 antigen, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. MUC16 is over-expressed by t... | |||
TMPH-01278 | ENOX2 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
May be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a ... | |||
TMPH-01277 | ENOX2 Protein, Human, Recombinant | Human | E. coli |
May be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a ... | |||
TMPJ-00148 | FOLR1 Protein, Rhesus macaque, Recombinant (His) | Rhesus | HEK293 Cells |
FOLR1 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 28-38 kDa and the accession number is F7BP60. | |||
TMPY-00117 | FGF-16 Protein, Human, Cynomolgus, Recombinant | Human,Cynomolgus | Baculovirus Insect Cells |
Fibroblast growth factor 16 (FGF16) is preferentially expressed in the heart after birth, suggesting its regulation is associated with tissue-specific chromatin remodeling and DNA-protein interactions. Mutation of the ME... | |||
TMPY-00566 | CCL18 Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
CCL18 is a chemotactic cytokine involved in the pathogenesis and progression of various disorders, including cancer. Proof showed high levels of CCL18 in the serum of epithelial ovarian carcinoma patients suggesting its... | |||
TMPY-05176 | AMH Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Anti-Mullerian hormone (AMH), a member of the TGF-beta superfamily, is produced by granulosa cells (GCs) of preantral and small antral follicles and plays a role in regulating the recruitment of primordial follicles and ... | |||
TMPH-00498 | Prorelaxin Protein, Canine, Recombinant (His) | Canine | E. coli |
Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. Prorelaxin Protein, Canine, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. Th... | |||
TMPY-03979 | ARHI Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
ARHI, also known as DIRAS3, belongs to the small GTPase superfamily, Di-Ras family. ARHI gene is a novel tumor suppressor gene located on chromosome 1p31. Downregulation of ARHI expression has been detected in many types... | |||
TMPY-00025 | Mammaglobin B/SCGB2A1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
SCGB2A1 represented a novel, prognostic factor for CRC, and that expression of SCGB2A1 correlated with chemoresistance, radioresistance and cancer cell stemness. SCGB2A1 is a top differentially expressed gene in all majo... | |||
TMPK-00293 | Nectin-2 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Nectin-2 is an adhesion molecule that has been reported to play a role in tumor growth, metastasis and tumor angiogenesis. Nectin-2 expression in ovarian cancer may support tumor cell adhesion, leading to growth and lymp... | |||
TMPY-01299 | GMF gamma/GMFG Protein, Human, Recombinant (His) | Human | E. coli |
The glia maturation factor gamma (GMFG) is a cytokine-responsive protein in erythropoietin-induced and granulocyte-colony stimulating factor-induced hematopoietic lineage development. It may mediate the pluripotentiality... | |||
TMPK-00172 | B7-H4 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
B7-H4, also known as B7x and B7S1, is a 50-80 kDa glycosylated member of the B7 family of immunomodulatory proteins.B7-H4 is up-regulated in several carcinomas in correlation with tumor progression and metastasis. A solu... | |||
TMPJ-00050 | AG-3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Anterior Gradient Protein 2(AG-2) and Anterior Gradient Protein 3 (AG-3) are human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metasta... | |||
TMPK-00224 | BTN3A2 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
BTN3A2/BT3.2 butyrophilin mRNA expression by tumoral cells was previously identified as a prognostic factor in a small cohort of high grade serous epithelial ovarian cancer (HG-EOC).In conclusion, BT3.2 protein is a pote... | |||
TMPJ-00784 | Alkaline Phosphatase Protein, Human, Recombinant (aa 23-506, His) | Human | HEK293 Cells |
ALPP is a membrane protein and exits as a homodimer. ALPP is expressed only in normal term placenta, endocervix and fallopian tube and also in ovarian and proximal gastrointestinal tumors. It has been shown to play a rol... | |||
TMPK-01035 | SP17 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Sperm protein 17 (Sp17) is a highly conserved mammalian protein characterized in rabbit, mouse, monkey, baboon, macaque, human testis and spermatozoa. mRNA encoding Sp17 has been detected in a range of murine and human s... | |||
TMPK-00974 | SP17 Protein, Human, Recombinant (His) | Human | E. coli |
Sperm protein 17 (Sp17) is a highly conserved mammalian protein characterized in rabbit, mouse, monkey, baboon, macaque, human testis and spermatozoa. mRNA encoding Sp17 has been detected in a range of murine and human s... | |||
TMPK-01076 | GPA34/VSIG1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
VSIG1, a cell adhesion protein of the immunoglobulin superfamily, is preferentially expressed in stomach, testis, and certain gastric, esophageal and ovarian cancers. Here, we describe the expression patterns of three al... | |||
TMPK-01160 | GPA34/VSIG1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
VSIG1, a cell adhesion protein of the immunoglobulin superfamily, is preferentially expressed in stomach, testis, and certain gastric, esophageal and ovarian cancers. Here, we describe the expression patterns of three al... | |||
TMPJ-01010 | PLA2G16 Protein, Human, Recombinant (His) | Human | E. coli |
Group XVI Phospholipase A1/A2 (PLA2G16) belongs to the H-rev 107 family. PLA2G16 is expressed in a number of human tumors including ovarian carcinomas, lung carcinomas. PLA2G16 is involved in the regulation of differenti... | |||
TMPJ-00483 | DFF45 Protein, Human, Recombinant (His) | Human | E. coli |
DNA Fragmentation Factor Subunit Alpha (DFFA). DFFA exists as a heterodimer (DFF) with DFFB. DFF is activated once DFFA is cleaved by Caspase-3. The cleaved fragments of DFFA detach from DFFB (the active component of DFF... | |||
TMPK-00976 | AMHRII Protein, Human, Recombinant | Human | HEK293 Cells |
The aim of the current study was to explore whether anti-Müllerian hormone receptor II (AMHRII) genetic variants influence the hormonal profile and the ovarian response to standard gonadotropin stimulation of women under... | |||
TMPY-01992 | Kallikrein 8/KLK8 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Kallikrein-8, also known as Neuropsin, Serine protease 19, Serine protease TADG-14, Tumor-associated differentially expressed gene 14 protein, and KLK8 is a secreted protein that belongs to the peptidase S1 family and Ka... | |||
TMPY-00375 | VMO1 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
Vitelline membrane outer layer protein 1 (VMO1), a basic protein present in the outer layer of the vitelline membrane of eggs, plays essential roles in separating the yolk from the egg white and preventing infection from... | |||
TMPK-00977 | AMHRII Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
The aim of the current study was to explore whether anti-Müllerian hormone receptor II (AMHRII) genetic variants influence the hormonal profile and the ovarian response to standard gonadotropin stimulation of women under... | |||
TMPJ-01358 | DPP3 Protein, Human, Recombinant (His) | Human | E. coli |
Dipeptidyl peptidase 3(DPP3), is a member of the S9B family in clan SC of the serine proteases. DPP3 has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. This c... | |||
TMPY-04780 | VMO1 Protein, Human, Recombinant | Human | HEK293 Cells |
Vitelline membrane outer layer protein 1 (VMO1), a basic protein present in the outer layer of the vitelline membrane of eggs, plays essential roles in separating the yolk from the egg white and preventing infection from... | |||
TMPJ-00501 | CLEC3B Protein, Human, Recombinant (His) | Human | HEK293 Cells |
C-Type Lectin Domain Family 3 Member B (CLEC3B) is a serum and tissue protein and it contais a C-type lectin which binds to Ca++. CLEC3B is originally found in plasma, the concentrations approximately 10mg/l. It can bind... | |||
TMPJ-01125 | PEA15 Protein, Human, Recombinant | Human | E. coli |
Astrocyticphosphoprotein PEA-15 (PEA15) is a death effector domain (DED)-containing protein. PEA15 is mainly expressed in the central nervous system, principally in astrocytes. Increased PEA15 levels affect tumorigenesis... | |||
TMPY-04387 | AKT2 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
AKT (AK mouse plus Transforming or Thymoma) is a frequent oncogene expressed in most tissues which includes three isoforms AKT1, AKT2, and AKT3. Hyperactivation of AKT signaling is a central key in many human cancer prog... | |||
TMPY-03287 | RRM1 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
RRM1 is a subunit of ribonucleoside-diphosphate reductase which is constituted by two subunits. Ribonucleoside-diphosphate reductase is an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesi... | |||
TMPY-02398 | TLE3 Protein, Human, Recombinant (aa 484-772, GST) | Human | E. coli |
The association between high TLE3 expression and a favorable response to taxane-containing chemotherapy regimens was validated in patients with non-serous ovarian cancer. That TLE3 expression may serve as a marker of che... | |||
TMPJ-00227 | Follistatin 288 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Follistatin 288 is a secreted glycoprotein that was first identified as a follicle-stimulating hormone inhibiting substance in ovarian follicular fluid . Human follistatin 288 cDNA encodes a 317 amino acid (aa) protein w... | |||
TMPJ-00791 | HER2/ERBB2 Protein, Rat, Recombinant (E. coli, His) | Rat | E. coli |
ERBB2 belongs to the protein kinase superfamily, Tyr protein kinase family and EGF receptor subfamily. It contains a protein kinase domain. ERBB2 is widely expressed in epithelial cells, and amplification and/or overexpr... | |||
TMPY-04478 | IP6K1/IHPK1 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
IP6K1 (Inositol Hexakisphosphate Kinase 1) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. IHPK1 is an inositol hexaphosphate kinase (IHPK) protein that belongs to the inositol phosph... | |||
TMPY-04307 | GNRH2 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
GNRH2 (Gonadotropin-Releasing Hormone 2) is a Protein Coding gene. This gene is a member of the gonadotropin-releasing hormone (GnRH) gene family. Proteins encoded by members of this gene family are proteolytically cleav... | |||
TMPY-02522 | OTUB2 Protein, Human, Recombinant (His) | Human | E. coli |
Otubain 2 (OTUB2) is a member of DUBs that belong to the ovarian tumour (OTU) superfamily of proteins which consists of a five-stranded β-sheet sandwiched in between a small helical amino-terminal region consisting of α1... | |||
TMPY-01775 | AIM2 Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
AIM2, Absent In Melanoma 2 is a member of the interferon-inducible HIN-200 protein family that contains an amino-terminal pyrin domain and a carboxy-terminal oligonucleotide/oligosaccharide-binding domain, senses cytopla... | |||
TMPY-02120 | XPNPEP2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Aminopeptidase P (APP) is a hydrolase specific for N-terminal imido bonds, which are common to several collagen degradation products, neuropeptides, vasoactive peptides, and cytokines. A membrane-bound and soluble form o... | |||
TMPY-02651 | P63 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
Tumor protein p63 is a protein also known as transformation-related protein 63, TP63, and p63. Tumor protein p63 / p63 is a member of the p53 family of transcription factors whose members P53, p63, and p73 have similar f... | |||
TMPY-01190 | INHBB Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. The activin and inhibin protein complexes are both dimeric in structure, and, in each complex, the two ... | |||
TMPY-01846 | Activin A Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. The activin and inhibin protein complexes are both dimeric in structure, and, in each complex, the two ... | |||
TMPY-01826 | Relaxin 1/RLN1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Relaxin-1, also known as Prorelaxin H1 and RLN1, is a secreted protein that belongs to the insulin family. It is a peptide hormone that was first described in 1926 by Frederick Hisaw. Since its discovery as a reproductiv... | |||
TMPY-01249 | Cathepsin V Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Cathepsin V (CTSV), also known as Cathepsin L2, CTSL2, and CATL2, is a member of the peptidase C1 family. It is predominantly expressed in the thymus and testis. Cathepsin V is also expressed in corneal epithelium, and t... |
カタログ番号 | 製品名 | ||
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L2196 | Anti-Ovarian Cancer Compound Library | 1867 compounds | |
L4600 | Selected Plant-Sourced Compound Library | 3048 compounds | |
A unique collection of 3048 plant-sourced compounds that derived from 277 plant species for high throughput screening (HTS) and high content screening (HCS); |