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244

阻害剤

天然化合物

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T11831	LDN-27219		Others
	LDN-27219 is a potent hTGase inhibitor with IC50 of 0.6 uM.		Others
T6792	BQ-123	BQ123	Endothelin Receptor
	BQ-123 is a selective endothelin A receptor (ETA) antagonist with IC50 of 7.3 nM. Phase 2.		Endothelin Receptor
T5458	Darusentan	Lu-135252	Endothelin Receptor
	Darusentan (Lu-135252) is a potent inhibitor of endothelin signaling and function in both large and small arteries		Endothelin Receptor
T22459	Xanthinol Nicotinate	Angioamin,Complamin	Others
	Xanthinol Nicotinate (Complamin) is a potent vasodilator that can easily enter the cell and causes an increase in glucose metabolism resulting in an increased energy.		Others
T0145	Felodipine	CGH-869	Calcium Channel , Autophagy
	Felodipine (CGH-869) is a longlasting 1, 4-dihydropyridine calcium channel repressor.		Calcium Channel , Autophagy
T7764	CCG-222740		ROCK , Rho , Ras
	CCG-222740 is an inhibitor of Rho/MRTF pathway		ROCK , Rho , Ras
T7133	Anagliptin	SK-0403	Proteasome , DPP-4
	Anagliptin (SK-0403) is a potent Inhibitor of DPP-4(IC50 of 3.8 nM), for the treatment of type 2 diabetes mellitus.		Proteasome , DPP-4
T0096	Vardenafil	Vivanza,Levitra,Vardenafil hydrochloride	PDE
			PDE
T8405	Vardenafil hydrochloride		PDE
	Vardenafil hydrochloride is a New Phosphodiesterase Type 5(PDE5) Inhibitor, in the Treatment of Erectile Dysfunction in Men With Diabetes		PDE
T8976	PD-089828		EGFR , FGFR , PDGFR , Src
	PD 089828 is a competitive inhibitor of the receptor tyrosine kinases FGFR1, PDGFRβ, and EGFR (IC50s = 0.15, 1.76, and 5.47 µM, respectively) and a noncompetitive inhibitor of the nonreceptor tyrosine kinase c-Src (IC50 ...		EGFR , FGFR , PDGFR , Src
T3461	Losartan Carboxylic Acid	EXP-3174,E-3174	RAAS
	Losartan Carboxylic Acid (E-3174) a potent AT1 antagonist (Kis: 0.57 nM, rat; 0.67 nM, human), producing a depressor response and vasodilatation. Losartan Carboxylic Acid , a metabolite of losartan, is more potent than l...		RAAS
T1487	Fluvastatin sodium	XU 62320 sodium,XU-62-320,Fluvastatin sodium salt	Ferroptosis , HMG-CoA Reductase , Autophagy
	Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol lowering agent.		Ferroptosis , HMG-CoA Reductase , Autophagy
T4097	Vardenafil hydrochloride trihydrate	Vardenafil HCl Trihydrate,BAY38-9456	PDE
	Vardenafil hydrochloride trihydrate (BAY38-9456) is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively.		PDE
T1083L	Theophylline monohydrate	Quibron	HDAC , PDE , Adenosine Receptor
	Theophylline monohydrate (Quibron) appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calcium distribution, and antagonize adenosine. Theophylline monohydrate is a ...		HDAC , PDE , Adenosine Receptor
T4480	Vardenafil dihydrochloride	Levitra,Vardenafil Hydrochloride	PDE
	Vardenafil dihydrochloride (Levitra) is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively.		PDE
T3996	Dapiprazole Hydrochloride	Glamidolo Hydrochloride,Reversil Hydrochloride	Adrenergic Receptor
	Dapiprazole Hydrochloride (Glamidolo Hydrochloride) is an alpha-1-adrenergic antagonist that acts by blocking alpha-adrenergic receptors in the smooth muscle of blood vessels (arteries, arterioles and veins), gastrointes...		Adrenergic Receptor
T25719	Lidamidine	Lidamidina,Lidamidinum	Others
	Lidamidine (Lidamidinum) is an effective antidiarrheal agent that inhibits intestinal secretion, reduces intestinal transit, and inhibits smooth muscle contraction.		Others
T14021	20-HETE	20-hydroxy Arachidonic Acid	Others
	20-HETE (20-hydroxy Arachidonic Acid) is a CYP450 metabolite and a potent vasoconstrictor and it is an endogenous inhibitor of the large-conductance Ca2+-activated K+ channel in renal arterioles. 20-HETE increases NADPH ...		Others
T1613	Hydralazine hydrochloride	Hydralazine HCl,Apresoline	MAO , HIF/HIF Prolyl-Hydroxylase
	Hydralazine hydrochloride (Apresoline) is the hydrochloride salt of hydralazine, a phthalazine derivative with antihypertensive and potential antineoplastic activities. Hydralazine alters intracellular calcium release an...		MAO , HIF/HIF Prolyl-Hydroxylase
T0324	Isoxsuprine hydrochloride	Duvadilan,Isolait	Adrenergic Receptor , iGluR
	Isoxsuprine hydrochloride (Isolait) is a beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle.		Adrenergic Receptor , iGluR
T67911	(Iso)-Dehydroemetine	Dehydroisoemetine, (+/-)-,Dehydroisoemetine	Others
	(Iso)-Dehydroemetine (Dehydroisoemetine, (+/-)-) is a compound with antispasmolytic effect on smooth muscle.		Others
T34280	Regrelor disodium	INS-50589,INS50589,Regrelor sodium,Regrelor,INS 50589	P2Y Receptor
	Regrelor disodium (INS 50589) is a p2y12 receptor antagonist that prevents thrombosis, effectively inhibits vascular smooth muscle cell contraction, inhibits cell proliferation, and reduces inflammation.		P2Y Receptor
T7575L	[Sar1, Ile8]-Angiotensin II 3TFA	[Sar1, Ile8]-Angiotensin II 3TFA(37827-06-8(free base))	Others
	[Sar1, Ile8]-Angiotensin II 3TFA ([Sar1, Ile8]-Angiotensin II 3TFA (37827-06-8(free base))) is a peptide that has multiple effects on vascular smooth muscle.		Others
T34541	SB-209670	SB 209670	Endothelin Receptor
	SB-209670 is a selective endothelin receptor antagonist that inhibits the activity of ET(B) receptors in rat vascular endothelium and vascular smooth muscle.		Endothelin Receptor
T67951	JB061		Myosin
	JB061 is a nonmuscle myosin inhibitor, demonstrating selective inhibitory activity with IC50 values of 4.4 μM (Cardiac muscle myosin), 9.1 μM (Skeletal muscle myosin), and >100 μM (Smooth muscle myosin II). It exhibits l...		Myosin
T0504	Cyclandelate	BS 572,3,5,5-Trimethylcyclohexyl mandelate	Acyltransferase
	Cyclandelate (BS 572), a direct-acting smooth muscle relaxant, is used to dilate blood vessels.		Acyltransferase
T7575L1	[Sar1, Ile8]-Angiotensin II acetate		RAAS
	[Sar1, Ile8]-Angiotensin II acetate activates both the NADPH and NADH oxidases, and stimulates superoxide anion formation in vascular smooth muscle cells. [Sar1, Ile8]-Angiotensin II acetate has multiple effects on vascu...		RAAS
T15049	Daltroban	BM-13505,SKF 96148	PPAR
	Daltroban (SKF 96148) is a specific thromboxane A2 (TXA2) receptor antagonist. Daltroban shows protective effect in reperfusion injury. Daltroban increase intracellular calcium in vascular smooth muscle cells.		PPAR
T0343	Nimodipine	BAY-e 9736	Glucocorticoid Receptor , AhR , Calcium Channel , Autophagy
	Nimodipine (BAY-e 9736), a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells.		Glucocorticoid Receptor , AhR , Calcium Channel , Autophagy
T16564	PPADS tetrasodium		P2X Receptor , Na+/Ca2+ Exchanger
	PPADS tetrasodiuma is a potent P2X receptor antagonist and inhibitor of the inverse mode of Na/Ca²⁺ exchange in guinea pig airway smooth muscle and is neuroprotective against glutamate/NMDA toxicity.PPADS tetrasodiuma in...		P2X Receptor , Na+/Ca2+ Exchanger
T67952	JB062		Myosin
	JB062 is a chemical compound acting as a nonmuscle myosin inhibitor, exhibiting IC50 values of 1.6, 5.4, and >100 μM against skeletal muscle myosin, cardiac muscle myosin, and smooth muscle myosin II, respectively. It se...		Myosin
T21405	Fluvastatin	Canef,XU-62320,Vastin,Cranoc,Lescol	HMG-CoA Reductase
	Fluvastatin (XU-62320) is a potent and competitive HMG-CoA reductase inhibitor (IC50: 8 nM) that inhibits oxidative stress in vascular smooth muscle cells through an Nrf2-dependent pathway, and is used for the reduction ...		HMG-CoA Reductase
T21478	Cromakalim	BRL34915,(±)-Cromakalim,BRL 34915,BRL-34915	Potassium Channel
	Cromakalim (BRL 34915) is an ATP-dependent K(+) channel opener and a smooth muscle relaxant.Cromakalim has antiepileptic and anticonvulsant activity and may be useful in studies of asthma and disorders associated with va...		Potassium Channel
T13684	Equilin	7-Dehydroestrone	Calcium Channel
	Equilin (7-Dehydroestrone) is a neurotrophic estrogenic steroid with vasodilatory activity that increases monocyte-endothelial adhesion through NF-κB signalling.Equilin similarly relaxes mesenteric arterial resistance by...		Calcium Channel
T2441	TAS-301	TAS 301	PKC
	TAS-301, an inhibitor of smooth muscle cell migration and proliferation, inhibits intimal thickening after balloon injury to rat carotid arteries.		PKC
T71746	Pincainide		Others
	Pincainide is a novel beta-aminoaniline that inhibits, in a dose-dependent manner, diseases caused by abnormal norepinephrine vascular smooth muscle function.		Others
T28972	Tiaramide hydrochloride	FK-1160,NTA-194,FK 1160,FK1160,tiaramide	Others
	Tiaramide hydrochloride (FK-1160) is an anti-inflammatory drug that inhibits the action of mediators released from mast cells and has direct smooth muscle relaxant properties.		Others
T6968	Riociguat	BAY 632521	Guanylate cyclase
	Riociguat (BAY 632521) is a stimulator of guanylate cyclase which causes relaxation of vascular smooth muscle and is used to treat severe pulmonary arterial hypertension.		Guanylate cyclase
T1115	Doxylamine succinate	Decapryn	Histamine Receptor
	Doxylamine Succinate is a pyridine derivate histamine H1 antagonist with pronounced sedative properties. Doxylamine succinate (Decapryn) competitively blocks the histamine H1 receptor and limits the typical allergic and ...		Histamine Receptor
T11986L	Mebeverine acid hydrochloride
	Mebeverine acid hydrochloride is an effective, oral compound to act directly on the smooth muscle of the gastrointestinal tract to relieve spasticity symptoms.
T68002L	(R)-Naroparcil	4-[4-[(5-Thio-α-D-xylopyranosyl)thio]benzoyl]benzonitrile(Isomer-120819-70-7)	Others
	(R)-Naroparcil is an isomer of Naroparcil. Naroparcil, a 4-methylumbelliferyl beta-D-xyloside analog, is associated with vascular smooth muscle cell proliferation and inhibits thrombus formation in the Wessler slough mod...		Others
T5195	Alrestatin	AY-22284	Reductase
	Alrestatin (AY-22284) is a specific inhibitor of aldose reductase and attenuates glucose-induced angiotensin II production in rat vascular smooth muscle in vitro.		Reductase
T12255	NS19504		Potassium Channel
	NS19504 is an activator of Ca2+-activated K+ channel with EC50 of 11.0 µM. NS19504 shows relaxing effect on bladder smooth muscle spontaneous phasic contractions[1].		Potassium Channel
T2400	Candesartan Cilexetil	TCV-116	Apoptosis , RAAS
	Candesartan Cilexetil (TCV-116) is an angiotensin II receptor antagonist (IC50: 0.26 nM). After hydrolysis of candesartan cilexetil to candesartan during gastrointestinal absorption, candesartan selectively competes with...		Apoptosis , RAAS
TP2075L	Bombinakinin M acetate	Bombinakinin M acetate(509151-65-9 free base)	Bradykinin Receptor
	Bombinakinin M acetate is a potent bradykinin receptor agonist with high selectivity for mammalian arterial smooth muscle bradykinin receptors and is approximately 50 times more potent than bradykinin.		Bradykinin Receptor
T3194	Ro 46-2005		Endothelin Receptor
	Ro 46-2005 is a synthetic non-peptide endothelin receptor antagonist, inhibits the specific binding of 125I-ET-1 to human vascular smooth muscle cells (ETA receptor, IC50: 220 nM).		Endothelin Receptor
TNU0266	9-(β-D-Xylofuranosyl)adenine	Xylosyladenine,Adenine xyloside	Nucleoside Antimetabolite/Analog
	9-(β-D-Xylofuranosyl)adenine (Adenine xyloside) is an adenine nucleoside analog that is a potential smooth muscle vasodilator.9-(β-D-Xylofuranosyl)adenine has anticancer activity.		Nucleoside Antimetabolite/Analog
T1006	Propantheline bromide	Neopepulsan,Pro-Banthine,Neometantyl	AChR
	Propantheline bromide (Pro-Banthine) competitively antagonizes acetylcholine activity mediated by muscarinic receptors at neuroeffector sites on smooth muscle and exocrine gland cells. Propantheline Bromide is the bromid...		AChR
T0999	Clevidipine	Clevidipine butyrate,Cleviprex	Calcium Channel , AChR
	Clevidipine (Clevidipine butyrate) is a dihydropyridine L-type calcium channel blocker that is selective for vascular smooth muscle and is indicated for blood pressure reduction when oral therapy is not an option.		Calcium Channel , AChR
T11918L	Lysipressin acetate(50-57-7(fb_acetate))	Lysine vasopressin acetate,[Lys8]-Vasopressin acetate	Others
	Lysipressin acetate(50-57-7(fb_acetate)) ([Lys8]-Vasopressin acetate) , Induces contraction of the rabbit urinary bladder smooth muscle, activate adenylate-cyclase. Lysipressin is Antidiuretic hormone that have been foun...		Others

Compounds

Target: Endothelin Receptor

Darusentan

T5458

Synonym: Lu-135252

Target: Endothelin Receptor

Xanthinol Nicotinate

T22459

Synonym: Angioamin,Complamin

Target: Calcium Channel, Autophagy

CCG-222740

T7764

Synonym:

Target: ROCK, Rho, Ras

Anagliptin

T7133

Synonym: SK-0403

Target: Proteasome, DPP-4

Vardenafil

T0096

Synonym: Vivanza,Levitra,Vardenafil hydrochloride

Target: PDE

Vardenafil hydrochloride

Target: EGFR, FGFR, PDGFR, Src

Losartan Carboxylic Acid

T3461

Synonym: EXP-3174,E-3174

Target: RAAS

Fluvastatin sodium

T1487

Synonym: XU 62320 sodium,XU-62-320,Fluvastatin sodium salt

Target: Ferroptosis, HMG-CoA Reductase, Autophagy

Vardenafil hydrochloride trihydrate

T4097

Synonym: Vardenafil HCl Trihydrate,BAY38-9456

Target: PDE

Theophylline monohydrate

T1083L

Synonym: Quibron

Target: HDAC, PDE, Adenosine Receptor

Vardenafil dihydrochloride

T4480

Synonym: Levitra,Vardenafil Hydrochloride

Target: PDE

Dapiprazole Hydrochloride

T3996

Synonym: Glamidolo Hydrochloride,Reversil Hydrochloride

Target: Adrenergic Receptor

Lidamidine

T25719

Synonym: Lidamidina,Lidamidinum

Target: Others

20-HETE

T14021

Synonym: 20-hydroxy Arachidonic Acid

Target: Others

Hydralazine hydrochloride

T1613

Synonym: Hydralazine HCl,Apresoline

Target: MAO, HIF/HIF Prolyl-Hydroxylase

Isoxsuprine hydrochloride

T0324

Synonym: Duvadilan,Isolait

Target: Adrenergic Receptor, iGluR

(Iso)-Dehydroemetine

T67911

Synonym: Dehydroisoemetine, (+/-)-,Dehydroisoemetine

Target: Others

Regrelor disodium

T34280

Synonym: INS-50589,INS50589,Regrelor sodium,Regrelor,INS 50589

Target: P2Y Receptor

[Sar1, Ile8]-Angiotensin II 3TFA

T7575L

Synonym: [Sar1, Ile8]-Angiotensin II 3TFA(37827-06-8(free base))

Target: Endothelin Receptor

Synonym: BS 572,3,5,5-Trimethylcyclohexyl mandelate

Target: Acyltransferase

[Sar1, Ile8]-Angiotensin II acetate

Synonym: BM-13505,SKF 96148

Target: Glucocorticoid Receptor, AhR, Calcium Channel, Autophagy

PPADS tetrasodium

T16564

Synonym:

Target: P2X Receptor, Na+/Ca2+ Exchanger

Synonym: Canef,XU-62320,Vastin,Cranoc,Lescol

Target: HMG-CoA Reductase

Cromakalim

T21478

Synonym: BRL34915,(±)-Cromakalim,BRL 34915,BRL-34915

Target: Potassium Channel

Equilin

T13684

Synonym: 7-Dehydroestrone

Target: Calcium Channel

Tiaramide hydrochloride

T28972

Synonym: FK-1160,NTA-194,FK 1160,FK1160,tiaramide

Target: Guanylate cyclase

Doxylamine succinate

T1115

Synonym: Decapryn

Target: Histamine Receptor

Mebeverine acid hydrochloride

Synonym: 4-[4-[(5-Thio-α-D-xylopyranosyl)thio]benzoyl]benzonitrile(Isomer-120819-70-7)

Target: Potassium Channel

Candesartan Cilexetil

T2400

Synonym: TCV-116

Target: Apoptosis, RAAS

Bombinakinin M acetate

TP2075L

Synonym: Bombinakinin M acetate(509151-65-9 free base)

Target: Bradykinin Receptor

Ro 46-2005

T3194

Synonym:

Target: Endothelin Receptor

9-(β-D-Xylofuranosyl)adenine

TNU0266

Synonym: Xylosyladenine,Adenine xyloside

Target: Nucleoside Antimetabolite/Analog

Propantheline bromide

T1006

Synonym: Neopepulsan,Pro-Banthine,Neometantyl

Target: AChR

Clevidipine

T0999

Synonym: Clevidipine butyrate,Cleviprex

Target: Calcium Channel, AChR

Lysipressin acetate(50-57-7(fb_acetate))

T11918L

Synonym: Lysine vasopressin acetate,[Lys8]-Vasopressin acetate

Target: Others

カタログ番号	製品名	別名	ターゲット
T8198	Visnagin		Others
	Visnagin has acute hypotensive, anti-inflammatory, and neuroprotective effects, it protects against doxorubicin-induced cardiomyopathy through modulation of mitochondrial malate dehydrogenase.		Others
T1431	Khellin	Amicardine,Methafrone,Visammin	EGFR , Others
	Khellin (Methafrone) is a vasodilator that also has bronchodilatory action.		EGFR , Others
T1083	Theophylline	Theo-24,1,3-Dimethylxanthine	Endogenous Metabolite , HDAC , PDE , Adenosine Receptor , Autophagy
	Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3...
T3S0364	L-Arginine	L-Arg,(S)-(+)-Arginine	IL Receptor , Endogenous Metabolite , NO Synthase
	1. L-Arginine (L-Arg) exhibits anti-atherosclerotic effect. 2. L-Arginine and soy enriched diet are effective in prevention of osteoporosis associated with diabetes mellitus. 3. Exogenous L-Arginine could enhance neonate...		IL Receptor , Endogenous Metabolite , NO Synthase
T8288	14-Deoxyandrographolide		Apoptosis , Others
	14-Deoxyandrographolide is a bioactive compound of Andrographis paniculata with hepatoprotective efficacy. It desensitizes hepatocytes to TNF-α-mediated apoptosis through the release of TNFRSF1A release.		Apoptosis , Others
T2520	Desloratadine	Sch34117,NSC 675447	Endogenous Metabolite , Histamine Receptor
	Desloratadine (Sch34117) is a long-acting piperidine derivate with selective H1 antihistaminergic and non-sedating properties. Desloratadine diminishes the typical histaminergic effects on H1-receptors in bronchial smoot...		Endogenous Metabolite , Histamine Receptor
TN3243	7-O-Methyleriodictyol		AChR
	7-O-Methyleriodictyol is a flavanone isolated from Artemisia monosperma and shows biological effects on rat isolated smooth muscles.		AChR
T8178	Acetagastrodin	Acegastrodine	Others
	Acetagastrodin (Acegastrodine) has an antispasmodic effect on vascular smooth muscle.		Others
TN1683	Gentisin		DNA/RNA Synthesis
	Gentisin is a novel inhibitor of vascular smooth muscle cells (VSMC) proliferation with an IC50 value of 7.84 μM. Gentisin has mutagenic activity.		DNA/RNA Synthesis
T20604L	Litorin acetate(55749-97-8 Free base)		Bombesin Receptor
	Litorin acetate, an amphibian bombesin peptide derivative, is an bombesin receptor agonist. It stimulates the contraction of smooth muscle, stimulates gastrin, gastric acid, and pancreatic secretion, and suppresses the n...		Bombesin Receptor
T0892	Diphylline	Dyphylline,Diprophylline	PDE , Adenosine Receptor
	Diphylline (Diprophylline) is a xanthine derivative. Diphylline exerts bronchodilator effects and to a lesser extent vasodilator and diuretic properties. Diphylline probably acts as a competitive inhibitor of phosphodies...		PDE , Adenosine Receptor
TN1248	3-Epioleanolic acid		AChR
	3-Epioleanolic acid and oleanonic acid possess varying degrees of agonist activity on uterine smooth muscle with minor changes in the molecular structure affecting its intrinsic activity on uterine muscle.		AChR
T6S1418	Praeruptorin C		Antioxidant , Calcium Channel
	1. Praeruptorin C has been widely used as an antioxidant and a calcium antagonist to treat diseases. 2. Praeruptorin C partially protects cortical neurons by inhibiting the expression of GluN2B-containing NMDA receptors ...		Antioxidant , Calcium Channel
T3805	Prim-O-glucosylcimifugin	Cimifugin beta-D-glucopyranoside,Cimifugin 7-glucoside	TNF , COX , JAK , NO Synthase
	Prim-O-glucosylcimifugin (Cimifugin 7-glucoside) can inhibit the proliferation of SMC(smooth muscle cell) stimulated by TNF-alpha, increase the proportion of G0/G1 phase.		TNF , COX , JAK , NO Synthase
T6102	2'-acetylacteoside		Antioxidant , Reductase
	2'-Acetylacteoside has antioxidative activity. It can significantly attenuate glutamate-induced neurotoxicity at concentrations ranging from 0.1 to 10 μM. 2'-Acetylacteoside shows antiproliferative effects on aortic smoo...		Antioxidant , Reductase
T6534	Histamine dihydrochloride	peremin,Ceplene,Histamine 2HCl	Endogenous Metabolite , Histamine Receptor
	Histamine dihydrochloride (Ceplene) is dihydrochloride form of Histamine. Histamine is an organic nitrogen compound which is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodila...		Endogenous Metabolite , Histamine Receptor
T6S2025	8-O-Acetylharpagide	8-Acetylharpagide,3-Acetylharpagide,Acetylharpagide,8-O-Acetylharpagide	Antibacterial
	1. 8-O-Acetylharpagide has anti-inflammatory activity. 2. 8-O-Acetylharpagide has antibacteria and antiviral activities. 3. 8-O-Acetylharpagide has a biological activity on isolated smooth muscle preparations from guinea...		Antibacterial
T0965	Histamine	Ergamine	5-HT Receptor , Endogenous Metabolite , Histamine Receptor
	Histamine (Ergamine) is an amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting ne...		5-HT Receptor , Endogenous Metabolite , Histamine Receptor
T5014	Prostaglandin E2	PGE2,Dinoprostone,Prostaglandin E2 (PGE2)	Endogenous Metabolite , Prostaglandin Receptor
	Prostaglandin E2 (PGE2) is a naturally occurring hormone involved in a variety of physiological processes in the body, including smooth muscle contraction and relaxation, regulation of vasodilatation and constriction, re...		Endogenous Metabolite , Prostaglandin Receptor
T4S1102	Liensinine diperchlorate	Liensinine-Perchlorate	Mitophagy , Others , Autophagy
	Liensinine Diperchlorate is an isoquinoline alkaloid extracted from the embryonic seeds of the sacred lotus. It inhibits late autophagy by blocking autophagosome-lysosome fusion and exhibits biological activities such as...		Mitophagy , Others , Autophagy
T4S0998	Trifolirhizin		TNF , Tyrosinase
	Trifolirhizin exerts varying degrees of inhibition on tyrosinase-dependent melanin biosynthesis, and therefore, are candidates as skin-whitening agents.Trifolirhizin possesses potential anti-inflammatory and anti-cancer ...		TNF , Tyrosinase
T3427	Polydatin	Piceid,Polydotin Peceid	Apoptosis , Mitophagy , NF-κB , Autophagy
	Polydatin (Piceid), the glycoside of Resveratrol, is originally isolated from the Chinese herb Polygonum cuspidatum. The compound can inhibit platelet aggregation and elevate the ratios of LDL-C/HDL-C and TC/HDL-C. In th...		Apoptosis , Mitophagy , NF-κB , Autophagy
T37709	2,2,2-Trichloroethanol		Potassium Channel , Endogenous Metabolite
	2,2,2-Trichloroethanol, the active form of the sedative hypnotic drug chloral hydrate, is an agonist for the nonclassical K2P channels TREK-1 (KCNK2) and TRAAK (KCNK4)[1]. 2,2,2-trichloroethanol activates a nonclassical ...		Potassium Channel , Endogenous Metabolite
T5065	GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD	Monosodium-GMP,cGMP sodium salt,Cyclic GMP	PKA
	GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD (cGMP sodium salt) , also known as cGMP, is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, inc...		PKA
T6429	Caffeic Acid Phenethyl Ester	Phenylethyl Caffeate,CAPE	Apoptosis , NF-κB
	Caffeic Acid Phenethyl Ester (Phenylethyl Caffeate) (CAPE) inhibits the activation of nuclear transcription factor NF-kappa B and may suppress p70S6K and Akt-driven signaling pathways, with antineoplastic, cytoprotective...		Apoptosis , NF-κB
T1626	Prostaglandin E1	PGE1,Alprostadil	Endogenous Metabolite , Prostaglandin Receptor
	Prostaglandin E1 (Alprostadil) is the naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Prostaglandin E1 is a potent vasodilator agent that increases peripheral blood flow, in...		Endogenous Metabolite , Prostaglandin Receptor
T4S1619	L-Hyoscyamine sulfate	Hyoscyamine sulfate hydrate,Levsin Sulfate,Hyoscyamine Sulphate	AChR
	L-Hyoscyamine sulfate (Levsin Sulfate) is the sulfate salt of a belladonna alkaloid derivative and the levorotatory form of racemic atropine isolated from the plants Hyoscyamus niger or Atropa belladonna, which exhibits ...		AChR
T0962	L-Hyoscyamine	Daturine,Hyoscyamine	AChR
	L-Hyoscyamine (Daturine) functions as a non-selective, competitive antagonist of muscarinic receptors, thereby inhibiting the parasympathetic activities of acetylcholine on the salivary, bronchial, and sweat glands, as w...		AChR
T3229	Cytochalasin D		ATPase , p38 MAPK , Calcium Channel , Akt , PI3K
	Cytochalasin D is an actin inhibitor, the removal of actin stress fibers is crucial for the chondrogenic differentiation. It may be an inhibitor of some fertilization processes such as sperm penetration or sperm head dec...		ATPase , p38 MAPK , Calcium Channel , Akt , PI3K
T3123	Allicin		ERK , IL Receptor , Others , IκB/IKK , p38 MAPK , TNF , ROS , Caspase , Antifection
	Allicin exerts antioxidant, bactericidal, anti-cancer, anti-inflammatory activities, it exerts an inhibitory immunomodulatory effect on intestinal epithelial cells. Allicin could significantly inhibit vascular smooth mus...
T5S0106	Peimisine	Ebeiensine	RAAS , AChR
	1. Peimisine (Ebeiensine) can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax tracheal smooth muscle and relieve asthma. 2. Pe...		RAAS , AChR
T3794	Pentagalloylglucose	Penta-O-galloyl-β-D-glucose,1,2,3,4,6-O-Pentagalloylglucose,1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose	Influenza Virus
	1, 2, 3, 4, 6-Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) and gallic acid from Pistacia lentiscus have antimutagenic and antioxidant activities. 2. 1, 2, 3, 4, 6-Penta-O-galloyl-beta-D-glucose (PGG) possesses poten...		Influenza Virus
T20604	Litorin
	Litorin, an amphibian bombesin peptide derivative, is found to suppress the nutriment, to stimulate the contraction of smooth muscle, to stimulate gastrin, gastric acid, and pancreatic secretion.
TN1338	7Beta-Hydroxycholesterol		LDL , Calcium Channel , MAPK
	7beta-Hydroxycholesterol, a major cytotoxin in oxidized LDL, induces Ca(2+) oscillations, MAP kinase activation and apoptosis in human aortic smooth muscle cells.		LDL , Calcium Channel , MAPK
TN5341	Pterosin Z
	Pterosin Z has smooth muscle relaxant activity, is approximately equipotent with that of the related fungal pterosin (EC50 of 2.9 +/- 1.6 x 10(-6) M).
TN4051	Fargesone B		cAMP , Calcium Channel
	Fargesone B inhibits the vascular smooth muscle contraction by suppressing the voltage- and receptor-activated calcium influxes in a nonselective manner.		cAMP , Calcium Channel
TN5234	Vindorosine		Calcium Channel , Sodium Channel
	Vindorosine has blood vessel relaxation effect, possible underlying mechanisms involving the inhibition of Ca(2+) entry via L-type Ca(2+) channels in vascular smooth muscles.		Calcium Channel , Sodium Channel
TN1875	Liriodenine		BCL , Caspase , p53
	Liriodenine is a potent inhibitor of topoisomerase II (EC 5.99.1.3) both in vivo and in vitro, it has antitumor, antibacterial and antifungal activities, it can suppress ventricular arrhythmias induced by myocardial isch...		BCL , Caspase , p53
TN5608	Paspalinine
	Paspalinine can inhibit binding of [125I]charybdotoxin (ChTX) to maxi-K channels in bovine aortic smooth muscle sarcolemmal membranes. Paspalinine shows tremorgenic action, which may be due in part to their inhibition of...
TN2075	Pimaric acid		MMP , p38 MAPK , NF-κB
	Pimaric acid has potent anti-atherosclerotic activity with inhibitory action on matrix metalloproteinase-9 production and cell migration in TNF-α±-induced human aortic smooth muscle cells.		MMP , p38 MAPK , NF-κB
TN3319	9-Hydroxycanthin-6-one		Potassium Channel , GSK-3 , Calcium Channel , Wnt/beta-catenin
	9-Hydroxycanthin-6-one might be the active component that contributed to the aphrodisiac effect of E. longifolia by antagonizing the smooth muscle tone of CC as well as SV probably through interfering with Ca2+ mobilizat...
TN1985	Neoprzewaquinone A		ROCK , Pim , STAT
	Neoprzewaquinone A (NEO), an active ingredient of S. miltiorrhiza, inhibits breast cancer cell migration and promotes smooth muscle relaxation by targeting PIM1 and blocking the ROCK2/STAT3 pathway.		ROCK , Pim , STAT
T83454	13-Hydroxylupanine hydrochloride	Hydroxylupanine hydrochloride
	13-Hydroxylupanine, a characteristic alkaloid of sweet lupins, inhibits ganglionic transmission, reduces cardiac contractility, and induces contraction of uterine smooth muscle [1].
T74193	(R)-IDHP
	(R)-IDHP, an isomer of IDHP and a metabolite of salvia, exhibits vasorelaxant properties by inhibiting calcium (Ca 2+) release and inward flow through both voltage-dependent and receptor-operated calcium channels in vasc...
T25687	Leukotriene C4	LTC4,Leukotriene C
	Leukotriene C4 is the conjugation product of Leukotriene A4 and glutathione. It is the major arachidonic acid metabolite in human mast cells, macrophages, and antigen-sensitized lung tissue. It stimulates mucus secretion...
TN5330	Lacinilene C	3,10-Dihydroxy-1,3,5,7-cadinatetraen-9-one
	Lacinilene C, lacinilene C 7-methyl ether, scopoletin, 2-hydroxy-7-methoxycadalene and 2,7-dihydroxycadalene are 5 induced phytoalexins in cotton leaves. Lacinilene C methyl ether elicits contraction of TSM by enhancing ...
TN5186	Triptoquinone A		IL Receptor , NOS
	Triptoquinone A may be a useful candidate for the development of a drug as a potent inhibitor of iNOS gene over-expression. Triptoquinone A has anti-inflammatory activity, it prevents ndotoxin-or interleukin-1 beta-promo...		IL Receptor , NOS
TN1690	Glabrene		Others , Estrogen/progestogen Receptor , Tyrosinase
	Glabrene, Liquiritin apioside, neolicuroside, and 18α²-glycyrrhetic acid are the predominant phenolic derivatives partitioning at the interface and most likely the major contributors to the notable synergistic antioxidan...		Others , Estrogen/progestogen Receptor , Tyrosinase
T72152	Eicosapentaenoic Acid sodium	Timnodonic acid sodium,EPA sodium
	Eicosapentaenoic Acid (EPA) sodium, an orally active omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA), demonstrates a unique ability to demethylate DNA, thereby facilitating the re-expression of the tumor supp...

天然物製品

Synonym: Amicardine,Methafrone,Visammin

Target: EGFR, Others

Theophylline

T1083

Synonym: Theo-24,1,3-Dimethylxanthine

Target: Endogenous Metabolite, HDAC, PDE, Adenosine Receptor, Autophagy

L-Arginine

T3S0364

Synonym: L-Arg,(S)-(+)-Arginine

Target: IL Receptor, Endogenous Metabolite, NO Synthase

14-Deoxyandrographolide

T8288

Synonym:

Target: Apoptosis, Others

Desloratadine

T2520

Synonym: Sch34117,NSC 675447

Target: Endogenous Metabolite, Histamine Receptor

7-O-Methyleriodictyol

Synonym: Acegastrodine

Target: DNA/RNA Synthesis

Litorin acetate(55749-97-8 Free base)

T20604L

Synonym:

Target: Bombesin Receptor

Diphylline

T0892

Synonym: Dyphylline,Diprophylline

Target: PDE, Adenosine Receptor

Target: Antioxidant, Calcium Channel

Prim-O-glucosylcimifugin

T3805

Synonym: Cimifugin beta-D-glucopyranoside,Cimifugin 7-glucoside

Target: TNF, COX, JAK, NO Synthase

2'-acetylacteoside

T6102

Synonym:

Target: Antioxidant, Reductase

Histamine dihydrochloride

T6534

Synonym: peremin,Ceplene,Histamine 2HCl

Target: Endogenous Metabolite, Histamine Receptor

8-O-Acetylharpagide

T6S2025

Synonym: 8-Acetylharpagide,3-Acetylharpagide,Acetylharpagide,8-O-Acetylharpagide

Target: Antibacterial

Histamine

T0965

Synonym: Ergamine

Target: 5-HT Receptor, Endogenous Metabolite, Histamine Receptor

Prostaglandin E2

T5014

Synonym: PGE2,Dinoprostone,Prostaglandin E2 (PGE2)

Target: Endogenous Metabolite, Prostaglandin Receptor

Liensinine diperchlorate

T4S1102

Synonym: Liensinine-Perchlorate

Target: Mitophagy, Others, Autophagy

Trifolirhizin

T4S0998

Synonym:

Target: TNF, Tyrosinase

Polydatin

T3427

Synonym: Piceid,Polydotin Peceid

Target: Apoptosis, Mitophagy, NF-κB, Autophagy

2,2,2-Trichloroethanol

T37709

Synonym:

Target: Potassium Channel, Endogenous Metabolite

GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD

T5065

Synonym: Monosodium-GMP,cGMP sodium salt,Cyclic GMP

Target: PKA

Caffeic Acid Phenethyl Ester

T6429

Synonym: Phenylethyl Caffeate,CAPE

Target: Apoptosis, NF-κB

Prostaglandin E1

T1626

Synonym: PGE1,Alprostadil

Target: Endogenous Metabolite, Prostaglandin Receptor

L-Hyoscyamine sulfate

T4S1619

Synonym: Hyoscyamine sulfate hydrate,Levsin Sulfate,Hyoscyamine Sulphate

Target: AChR

L-Hyoscyamine

T0962

Synonym: Daturine,Hyoscyamine

Target: ATPase, p38 MAPK, Calcium Channel, Akt, PI3K

Allicin

T3123

Synonym:

Target: ERK, IL Receptor, Others, IκB/IKK, p38 MAPK, TNF, ROS, Caspase, Antifection

Synonym: Penta-O-galloyl-β-D-glucose,1,2,3,4,6-O-Pentagalloylglucose,1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose

Target: Influenza Virus

7Beta-Hydroxycholesterol

TN1338

Synonym:

Target: LDL, Calcium Channel, MAPK

Target: cAMP, Calcium Channel

Vindorosine

TN5234

Synonym:

Target: Calcium Channel, Sodium Channel

Liriodenine

TN1875

Synonym:

Target: BCL, Caspase, p53

Target: MMP, p38 MAPK, NF-κB

9-Hydroxycanthin-6-one

TN3319

Synonym:

Target: Potassium Channel, GSK-3, Calcium Channel, Wnt/beta-catenin

Neoprzewaquinone A

TN1985

Synonym:

Target: ROCK, Pim, STAT

13-Hydroxylupanine hydrochloride

T83454

Synonym: Hydroxylupanine hydrochloride

Synonym: LTC4,Leukotriene C

Target:

Lacinilene C

TN5330

Synonym: 3,10-Dihydroxy-1,3,5,7-cadinatetraen-9-one

Target: IL Receptor, NOS

Glabrene

TN1690

Synonym:

Target: Others, Estrogen/progestogen Receptor, Tyrosinase

Eicosapentaenoic Acid sodium

T72152

Synonym: Timnodonic acid sodium,EPA sodium

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-01032	Calponin-2/CNN2 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inh...
TMPH-00882	ACTA2 Protein, Human, Recombinant (His)	Human	E. coli
	Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. ACTA2 Protein, Human, Recombinant (His) is expressed in E. coli expression ...
TMPH-01210	DENR Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	DENR Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 38.0 kDa and the accession number is O43583.
TMPJ-01210	IL-33 Protein, Mouse, Recombinant	Mouse	E. coli
	Mouse Interleukin 33 (IL-33) is a 30 kDa proinflammatory cytokine which may also regulates gene transcription in producer cells. IL-33 is constitutively expressed in smooth muscle and airway epithelia. IL-33 was identifi...
TMPJ-00562	PDGF-BB Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (P...
TMPJ-00071	EPO/Erythropoietin Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Erythropoietin (EPO) is a glycoprotein hormone that is principally known for its role in erythropoiesis, where it is responsible for stimulating proliferation and differentiation of erythroid progenitor cells. Erythropoi...
TMPJ-01261	PPP1R14A Protein, Human, Recombinant (His)	Human	E. coli
	Protein Phosphatase 1 Regulatory Subunit 14A (PPP1R14A) belongs to the PP1 inhibitor family. PPP1R14A is mapped to chromosome 19q13.13-q13.2. PPP1R14A binds directly to protein kinase C and casein kinase I. Meantime, PPP...
TMPY-03984	TPM1 Protein, Human, Recombinant (His)	Human	E. coli
	TPM1, also known as tropomyosin-1, is a member of the tropomyosin family. Members of this family are highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth m...
TMPH-01820	OXT Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Neurophysin 1 specifically binds oxytocin.; Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland. Acts by binding to oxytocin receptor (OXTR). OXT Protein, Human, Recombinant (His) is e...
TMPY-03600	TPM4 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	TPM4, also known as tropomyosin 4, is a member of the tropomyosin family. Members of this family are actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-mu...
TMPH-00780	CACNA1C Protein, Guinea Pig, Recombinant (His)	Guinea pig	E. coli
	Pore-forming, alpha-1C subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Mediates influx of calcium ions into the cytoplasm, and thereby triggers calcium release from the sarcoplasm...
TMPJ-01146	LGALSL Protein, Human, Recombinant (His)	Human	E. coli
	Galectin-Related Protein (LGALSL) is a 172 amino acid protein that contains one Galectin domain. LGALSL does not appear to bind carbohydrates or lactose as the critical residues required for binding are not conserved. LG...
TMPH-01821	OXT Protein, Human, Recombinant (His & Myc & SUMO)	Human	E. coli
	Neurophysin 1 specifically binds oxytocin.; Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland. Acts by binding to oxytocin receptor (OXTR). OXT Protein, Human, Recombinant (His & Myc...
TMPH-02253	TPM2 Protein, Human, Recombinant (His)	Human	E. coli
	Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contra...
TMPJ-00572	Vasorin Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Vasorin is a Type I membrane protein, which is predominantly expressed in vascular smooth muscle cells in a developmentally regulated pattern. The expression level of Vasorin can be down regulated during vessel repair af...
TMPH-03212	TPM1 Protein, Rabbit, Recombinant (His & Myc)	Rabbit	Baculovirus Insect Cells
	Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contra...
TMPH-02252	TPM3 Protein, Human, Recombinant (GST)	Human	E. coli
	Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contra...
TMPH-02636	Elastin Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulat...
TMPJ-00892	TAC1 Protein, Human, Recombinant (His)	Human	E. coli
	Protachykinin-1(TAC1) is a secreted protein and belongs to the tachykinin family. TAC1 is encoded by the TAC1 gene. This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, ...
TMPK-01269	CXCL10 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	E. coli
	C-X-C motif ligand 10 (CXCL10), or interferon-inducible protein-10, is a small chemokine belonging to the CXC chemokine family. Its members are responsible for leukocyte trafficking and act on tissue cells, like endothel...
TMPH-03069	CSL3 Protein, Oncorhynchus keta, Recombinant (His)	Oncorhynchus keta	E. coli
	L-rhamnose binding lectin. Has hemagglutinating activity towards rabbit erythrocytes, human type A erythrocytes, human type B erythrocytes, human type O erythrocytes and sheep erythrocytes. Hemagglutinating activity is i...
TMPH-03749	CYSLTR1 Protein, Human, Recombinant (His)	Human	E. coli
	Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and...
TMPH-03600	Glucosyltransferase-SI Protein, S. mutans serotype c, Recombinant (His & Myc)	Streptococcus mutans	E. coli
	Production of extracellular glucans, that are thought to play a key role in the development of the dental plaque because of their ability to adhere to smooth surfaces and mediate the aggregation of bacterial cells and fo...
TMPH-02500	AIF-1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage acti...
TMPH-03213	TPM1 Protein, Rabbit, Recombinant (E. coli, His & Myc)	Rabbit	E. coli
	Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contra...
TMPK-00617	IL-13 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Interleukin-13 (IL-13) is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast ce...
TMPH-03107	Complement C5a Protein, Pig, Recombinant (His)	Sus scrofa (Pig)	P. pastoris (Yeast)
	Derived from proteolytic degradation of complement C5, C5a anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, ...
TMPJ-00475	Kallikrein 1/KLK1 Protein, Human, Recombinant (aa 19-262, His)	Human	HEK293 Cells
	Kallikrein-1 (KLK1) is a member of human tissue Kallikrein family. Human KLK1 precursor contains a singal peptide (residues 1 to 18), a short pro peptide (residues 19 to 24) and a mature chain (residues 25 to 262). The f...
TMPH-02540	GRK2 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to...
TMPJ-01004	HDGF Protein, Human, Recombinant (His)	Human	E. coli
	Hepatoma-Derived Growth Factor is a original member of the HDGF family. HDGF is a cytoplasmic protein and contains one PWWP domain. HDGF expression levels are high in the nucleus and cytoplasm of smooth muscle and endoth...
TMPJ-01112	PRKG1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	cGMP-Dependent Protein Kinase 1 (PRKG1) belongs to the protein kinase superfamily and AGC Ser/Thr protein kinase family. PRKG1 contains one AGC-kinase C-terminal domain, two cyclic nucleotide-binding domains, and one pro...
TMPJ-00882	Desmin Protein, Human, Recombinant (His)	Human	E. coli
	Desmin is a cytoplasmic protein and belongs to the intermediate filament family. interacts with DST and MTM1. Desmin is only expressed in vertebrates, however homologous proteins are found in many organisms. Desmin is th...
TMPY-03058	SLITL2/VASN Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Vasorin is a typical type I membrane protein. It contains 1 EGF-like domain, 1 fibronectin type-III domain, 10 LRR (leucine-rich) repeats, 1 LRRCT domain and 1 LRRNT domain. Vasorin is predominantly expressed in vascular...
TMPJ-01379	TAC3 Protein, Human, Recombinant (His)	Human	E. coli
	Tachykinin 3 (TAC3) is a secreted protein that belongs to the Tachykinin family. Tachykinins are active peptides that excite neurons and evoke behavioral responses; they are potent vasodilators and secretagogues, and con...
TMPY-03337	Iba1 Protein, Human, Recombinant (His)	Human	E. coli
	AIF1, also known as IBA1, is an actin-binding protein. AIF1 is expressed selectively in human macrophage-like cell lines, and in a subset of CD68(+) macrophages in the interstitial and perivascular spaces of human hear...
TMPJ-00319	PFKFB3 Protein, Human, Recombinant (His)	Human	E. coli
	Fructose-2,6-biphosphatase 3, also known as 6-phosphofructo-2-kinase or PFK2 or PFKFB3, involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls the activity of the...
TMPJ-00402	CD117 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	C-Kit/SCF R is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to ...
TMPY-04207	Motilin Protein, Human, Recombinant (His)	Human	HEK293 Cells
	MLN (Motilin) is a Protein Coding gene. 3 alternatively spliced human isoforms have been reported. This gene encodes a small peptide hormone that is secreted by cells of the small intestine to regulate gastrointestinal c...
TMPJ-00361	Endoglin Protein, Human, Recombinant (Trx & His)	Human	E. coli
	Endoglin is a single-pass type I membrane protein which restricted to endothelial cells in all tissues except bone marrow. Endoglin as major glycoprotein of vascular endothelium, it has been found on endothelial cells, a...
TMPY-04471	APEG1 Protein, Human, Recombinant (His)	Human	E. coli
	Striated muscle preferentially expressed protein kinase, also known as aortic preferentially expressed protein 1, APEG-1, SPEG and KIAA1297, is a protein that belongs to the protein kinase superfamily and CAMK Ser/Thr pr...
TMPH-01297	DDR1 Protein, Human, Recombinant (aa 21-417, His)	Human	HEK293 Cells
	Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival ...
TMPY-02945	Prokineticin 1/EG-VEGF Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	EG-VEGF, also known as prokineticin-1, is a member of the AVIT (prokineticin) family. Prokineticins are secreted proteins that can promote angiogenesis and induce strong gastrointestinal smooth muscle contraction. EG-VEG...
TMPJ-00305	SIRP alpha Protein, Cynomolgus, Recombinant (aa 31-369, His)	Cynomolgus	HEK293 Cells
	Signal Regulatory Protein α (SIRPα) is a monomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRPα contains two Ig-like C1-type domains and one Ig-like V-type domain. SIRPα can expre...
TMPY-01484	THSD1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Thrombospondin type-1 domain-containing protein 1, also known as transmembrane molecule with thrombospondin module, THSD1 and TMTSP, is a single-pass type I membrane protein that contains one TSP type-1 domain. THSD1 is ...
TMPJ-00306	SIRP alpha Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Signal Regulatory Protein α (SIRPα) is a monomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRPα contains two Ig-like C1-type domains and one Ig-like V-type domain. SIRPα can expre...
TMPY-04761	Creatine kinase B Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	CKB(Creatine kinase B type) contains 1 phosphagen kinase C-terminal domain and 1 phosphagen kinase N-terminal domain. It belongs to the ATP:guanido phosphotransferase family. CKB consists of a homodimer of two identical...
TMPJ-00330	GPC1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	The Glypicans are a small multigene family of GPI-linked proteoglycans that play a key role in growth factor signaling. Human Glypican 1 (GPC1) is synthesized as a 558 amino acid (aa) preproprecursor that contains a 23 a...
TMPJ-00028	CCL2 Protein, Mouse, Recombinant	Mouse	E. coli
	C-C motif chemokine 2 (CCL2) is a member of the C-C or β chemokine family. Mouse CCL2 shares 82% amino acid (aa) identity with rat CCL2 over the entire sequence, and 58%, 56%, 55%, 53% and 53% aa identity with human, equ...
TMPJ-00741	PTH Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Parathyroid hormone (PTH) is a critical hormone in the regulation of Ca++ homeostasis. Parathyroid hormone is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid. This ho...
TMPH-02526	Arginase-2/ARG2 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synth...
------------------------ More ------------------------

Calponin-2/CNN2 Protein, Human, Recombinant (His & SUMO)

TMPH-01032

Species: Human

Expression System: E. coli

ACTA2 Protein, Human, Recombinant (His)

TMPH-00882

Species: Human

Expression System: E. coli

DENR Protein, Human, Recombinant (His & SUMO)

TMPH-01210

Species: Human

Expression System: E. coli

IL-33 Protein, Mouse, Recombinant

TMPJ-01210

Species: Mouse

Expression System: E. coli

PDGF-BB Protein, Mouse, Recombinant (His)

TMPJ-00562

Species: Mouse

Expression System: E. coli

EPO/Erythropoietin Protein, Human, Recombinant (His)

TMPJ-00071

Species: Human

Expression System: HEK293 Cells

PPP1R14A Protein, Human, Recombinant (His)

TMPJ-01261

Species: Human

Expression System: E. coli

TPM1 Protein, Human, Recombinant (His)

TMPY-03984

Species: Human

Expression System: E. coli

OXT Protein, Human, Recombinant (His)

TMPH-01820

Species: Human

Expression System: P. pastoris (Yeast)

TPM4 Protein, Human, Recombinant (His)

TMPY-03600

Species: Human

Expression System: HEK293 Cells

CACNA1C Protein, Guinea Pig, Recombinant (His)

TMPH-00780

Species: Guinea pig

Expression System: E. coli

LGALSL Protein, Human, Recombinant (His)

TMPJ-01146

Species: Human

Expression System: E. coli

OXT Protein, Human, Recombinant (His & Myc & SUMO)

TMPH-01821

Species: Human

Expression System: E. coli

TPM2 Protein, Human, Recombinant (His)

TMPH-02253

Species: Human

Expression System: E. coli

Vasorin Protein, Human, Recombinant (His)

TMPJ-00572

Species: Human

Expression System: HEK293 Cells

TPM1 Protein, Rabbit, Recombinant (His & Myc)

TMPH-03212

Species: Rabbit

Expression System: Baculovirus Insect Cells

TPM3 Protein, Human, Recombinant (GST)

TMPH-02252

Species: Human

Expression System: E. coli

Elastin Protein, Mouse, Recombinant (His)

TMPH-02636

Species: Mouse

Expression System: E. coli

TAC1 Protein, Human, Recombinant (His)

TMPJ-00892

Species: Human

Expression System: E. coli

CXCL10 Protein, Cynomolgus, Recombinant (His)

TMPK-01269

Species: Cynomolgus

Expression System: E. coli

CSL3 Protein, Oncorhynchus keta, Recombinant (His)

TMPH-03069

Species: Oncorhynchus keta

Expression System: E. coli

CYSLTR1 Protein, Human, Recombinant (His)

TMPH-03749

Species: Human

Expression System: E. coli

Glucosyltransferase-SI Protein, S. mutans serotype c, Recombinant (His & Myc)

TMPH-03600

Species: Streptococcus mutans

Expression System: E. coli

AIF-1 Protein, Mouse, Recombinant (His)

TMPH-02500

Species: Mouse

Expression System: E. coli

TPM1 Protein, Rabbit, Recombinant (E. coli, His & Myc)

TMPH-03213

Species: Rabbit

Expression System: E. coli

IL-13 Protein, Human, Recombinant (His & Avi)

TMPK-00617

Species: Human

Expression System: HEK293 Cells

Complement C5a Protein, Pig, Recombinant (His)

TMPH-03107

Species: Sus scrofa (Pig)

Expression System: P. pastoris (Yeast)

Kallikrein 1/KLK1 Protein, Human, Recombinant (aa 19-262, His)

TMPJ-00475

Species: Human

Expression System: HEK293 Cells

GRK2 Protein, Mouse, Recombinant (His & SUMO)

TMPH-02540

Species: Mouse

Expression System: E. coli

HDGF Protein, Human, Recombinant (His)

TMPJ-01004

Species: Human

Expression System: E. coli

PRKG1 Protein, Human, Recombinant (His)

TMPJ-01112

Species: Human

Expression System: HEK293 Cells

Desmin Protein, Human, Recombinant (His)

TMPJ-00882

Species: Human

Expression System: E. coli

SLITL2/VASN Protein, Human, Recombinant (His)

TMPY-03058

Species: Human

Expression System: HEK293 Cells

TAC3 Protein, Human, Recombinant (His)

TMPJ-01379

Species: Human

Expression System: E. coli

Iba1 Protein, Human, Recombinant (His)

TMPY-03337

Species: Human

Expression System: E. coli

PFKFB3 Protein, Human, Recombinant (His)

TMPJ-00319

Species: Human

Expression System: E. coli

CD117 Protein, Human, Recombinant (hFc)

TMPJ-00402

Species: Human

Expression System: HEK293 Cells

Motilin Protein, Human, Recombinant (His)

TMPY-04207

Species: Human

Expression System: HEK293 Cells

Endoglin Protein, Human, Recombinant (Trx & His)

TMPJ-00361

Species: Human

Expression System: E. coli

APEG1 Protein, Human, Recombinant (His)

TMPY-04471

Species: Human

Expression System: E. coli

DDR1 Protein, Human, Recombinant (aa 21-417, His)

TMPH-01297

Species: Human

Expression System: HEK293 Cells

Prokineticin 1/EG-VEGF Protein, Human, Recombinant (His)

TMPY-02945

Species: Human

Expression System: Baculovirus Insect Cells

SIRP alpha Protein, Cynomolgus, Recombinant (aa 31-369, His)

TMPJ-00305

Species: Cynomolgus

Expression System: HEK293 Cells

THSD1 Protein, Mouse, Recombinant (His)

TMPY-01484

Species: Mouse

Expression System: HEK293 Cells

SIRP alpha Protein, Human, Recombinant (His & Avi), Biotinylated

TMPJ-00306

Species: Human

Expression System: HEK293 Cells

Creatine kinase B Protein, Human, Recombinant (His)

TMPY-04761

Species: Human

Expression System: Baculovirus Insect Cells

GPC1 Protein, Human, Recombinant (His)

TMPJ-00330

Species: Human

Expression System: HEK293 Cells

CCL2 Protein, Mouse, Recombinant

TMPJ-00028

Species: Mouse

Expression System: E. coli

PTH Protein, Human, Recombinant (His)

TMPJ-00741

Species: Human

Expression System: HEK293 Cells

Arginase-2/ARG2 Protein, Mouse, Recombinant (His & SUMO)

TMPH-02526

Species: Mouse

Expression System: E. coli

--------- More ---------

カタログ番号	製品名
L5400	Anti-Cardiovascular Disease Compound Library	1408 compounds
	A unique collection of 1408 cardiovascular diseases related compounds for high throughput screening (HTS) and high content screening (HCS);
L7110	Anti-Hypertension Compound Library	678 compounds
	678 hypertension-related small molecules for high-throughput and high-content screening.

ライブラリー

Anti-Cardiovascular Disease Compound Library

L5400

Compounds: 1408

Anti-Hypertension Compound Library

L7110

Compounds: 678