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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T9582 | CLEFMA | NF-κB | |
CLEFMA has anti-proliferative activity. CLEFMA inhibits tumor growth associated with NF-κB-regulated anti-inflammatory and anti-metastatic effects. | |||
T8217 | Enzalutamide carboxylic acid | Androgen Receptor , Drug Metabolite | |
Enzalutamide carboxylic acid is an antagonist of androgen receptor (AR) . | |||
T8310 | MMP-9-IN-1 | MMP | |
MMP-9-IN-1 is an inhibitor of specific matrix metalloproteinase-9 (MMP-9). | |||
T12695 | RBN-2397 | PARP | |
RBN-2397 is a potent, selective and orally active accross species NAD+ competitive PARP7 inhibitor with IC50 less than 3 nM. | |||
T22263 | Bavdegalutamide | ARV-110 | Androgen Receptor |
Bavdegalutamide (ARV-110) is a PROTAC degrader of androgen receptor (AR). Bavdegalutamide can be used in studies about prostate cancer. Bavdegalutamide shows oral activity and selectivity and facilitates the ubiquitinati... | |||
T10297L | AMG 487 | CXCR | |
AMG 487 is a potent and selective antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively. | |||
T1855 | ZCL278 | ZCL 278 | CDK , Ras |
ZCL278 is a selective Cdc42 GTPase inhibitor. | |||
T12006 | Metarrestin | ML246 | DNA/RNA Synthesis |
Metarrestin (ML246) is a first-in-class perinucleolar compartment inhibitor with a favorable PK profile, which effectively suppresses metastasis. Metarrestin disrupts the nucleolar structure and inhibits RNA polymerase (... | |||
T27730 | KGP94 | KGP-94,KGP 94 | Cysteine Protease |
KGP94 is an inhibitor of cysteine protease Cathepsin L(CTSL). | |||
T1120 | Dacarbazine | Imidazole Carboxamide,DTIC-Dome | Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis |
Dacarbazine (DTIC-Dome) is an antineoplastic agent. It has significant activity against melanomas. | |||
T5125 | LY3200882 | TGF-beta/Smad | |
LY3200882 is a highly selective inhibitor of TGF-β receptor type 1 (TGFβRI). | |||
T8327 | ONO-7475 | Trk receptor , TAM Receptor | |
ONO-7475 is an inhibitor with high specificity for anexelekto and MER tyrosine kinase | |||
T22450 | Tyrphostin B44, (+) enantiomer | EGFR | |
Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with IC50 of 0.86 μM and has less active than the (-) enantiomer. | |||
T13687 | Eribulin mesylate | B1939 mesylate,ER-086526 mesylate,E7389 mesylate | Apoptosis , Others , Microtubule Associated |
Eribulin mesylate (E7389 mesylate) (E7389 mesylate) inhibits the proliferation of cancer cells by binding microtubule proteins and microtubules. Eribulin mesylate (E7389 mesylate) is a microtubule targeting agent that is... | |||
T35300 | Zeniplatin | Zeniplatinum | Others |
Zeniplatin (Zeniplatinum) is a new cisplatin complex with anticancer activity for the treatment of metastatic melanoma and kidney cancer. | |||
T13688 | Eribulin | B1939,ER-086526,E7389 | Others |
Eribulin inhibits the proliferation of cancer cells by binding microtubule proteins and microtubules. Eribulin is a microtubule targeting agent that is used in the treatment of metastatic breast cancer. | |||
T17255 | WJ460 | Others | |
WJ460 is an effective inhibitor of myoferlin. WJ460 exerts anti-metastatic activity in breast cancer cells. | |||
T27319 | FIIN-4 | FIIN4 | FGFR |
FIIN-4 is a covalent inhibitor of FGFR and can be used in studies about metastatic breast cancer. | |||
T9236 | WSB1 Degrader 1 | Others , E1/E2/E3 Enzyme | |
WSB1 Degrader 1 is a potent, orally active degrader of WD repeat and SOCS box-containing 1, exhibiting anti-cancer metastatic effects. | |||
T2113 | PHA-793887 | PHA 793887,PHA793887 | Apoptosis , CDK |
PHA-793887 has been used in trials studying the treatment of Advanced/Metastatic Solid Tumors. | |||
T39403 | Avotaciclib | BEY1107,Avotaciclib | CDK |
Avotaciclib (BEY1107) is a potent and orally active cyclin dependent kinase 1 (CDK1) inhibitor.Avotaciclib can be used to study locally advanced or metastatic pancreatic cancer. | |||
T62536 | S100P-IN-1 | Others | |
S100P-IN-1 is a potent S100P inhibitor.S100P-IN-1 has anti-metastatic effects on pancreatic cancer (pancreatic) cells. | |||
T9075 | BDP-13176 | Others | |
BDP-13176 is a potent inhibitor of fascin 1(Kd of 90 nM and an IC50 of 240 nM). It has potential as an anti-metastatic agent | |||
T21808 | Inotilone | Others | |
Inotilone is a major component of Inonotus linteus, a traditional Chinese medical herb and can be used for research of metastatic lung cancer cells. | |||
T6215 | Abiraterone Acetate | Zytiga,CB7630 | P450 |
Abiraterone Acetate (CB7630) is an androstene derivative that inhibits STEROID 17-ALPHA-HYDROXYLASE and is used as an ANTINEOPLASTIC AGENT in the treatment of metastatic castration-resistant PROSTATE CANCER. | |||
T4022 | QS11 | QS 11 | GTPase |
QS11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. Modulates ARF-GTP levels and synergizes with the Wnt/β-catenin signaling pathway to upregulate β-catenin nuclear translocation. Also r... | |||
T12433 | PF-06952229 | PF06952229 | TGF-beta/Smad |
PF-06952229 is a selective inhibitor of TGFβRI. PF-06952229 can be used in studies about the treatment of solid tumors, specifically metastatic breast cancer. | |||
T22136 | PRL-3 Inhibitor I | PRL-3 Inhibitor,BR-1 | Phosphatase , Others |
PRL-3 Inhibitor I (BR-1) is a phosphatase of regenerating liver 3 (PRL-3) inhibitor which blocks the migration and invasion of metastatic cancer cells. | |||
T76866 | Icrucumab | LY 3012212,IMC-18F1 | VEGFR |
Icrucumab ( IMC-18F1) is a humanized IgG1 monoclonal antibody targeting vascular endothelial growth factor receptor-1.Icrucumab has antitumor activity.Icrucumab has been studied in metastatic colon cancer. | |||
T26969 | CCT365623 | CCT-365623,CCT 365623 | Monoamine Oxidase |
CCT365623 is an orally bioavailable Lysyl Oxidase inhibitor with good anti-LOX potency, selectivity, pharmacokinetic properties, as well as anti-metastatic efficacy. | |||
T24644 | Piritrexim | BW 301U | DHFR |
Piritrexim (BW 301U) is an orally available fat-soluble dihydrofolate reductase inhibitor with pulmonary toxicity used in the study of uroepithelial carcinoma and metastatic breast cancer. | |||
T2618 | LGK974 | LGK 974,LGK-974,NVP-LGK974,WNT974 | Porcupine |
LGK974 (NVP-LGK974) is an effective and selective PORCN inhibitor and inhibits Wnt signaling (IC50: 0.4 nM) in TM3 cells. It has been used in trials studying the treatment of Metastatic Colorectal Cancer and Squamous Cel... | |||
T2381 | Abemaciclib | CDK4/6 dual inhibitor,LY2835219 | CDK |
Abemaciclib (LY2835219) is a dual inhibitor of CDK4/6 (IC50=2/10 nM) with selectivity and specificity. Abemaciclib has antitumor activity and is used to treat advanced or metastatic breast cancer. | |||
T9912 | Trastuzumab | EGFR | |
Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2. Trastuzumab has been clinically used to treat HER2 Positive Metastatic Breast Cancer and HER2 Positive Gastr... | |||
T77138 | Ragifilimab | INCAGN-01876,INCAGN-1876,CM-701 | TNF |
Ragifilimab (INCAGN-1876) is an agonist monoclonal antibody targeting glucocorticoid-induced TNFR-associated protein (GITR). Ragifilimab can be used in the study of advanced or metastatic solid tumors. | |||
T0078 | Lapatinib | GSK572016,GW572016 | EGFR , Ferroptosis , Autophagy |
Lapatinib (GW572016) is an inhibitor of ErbB2 and EGFR (IC50=9.2/10.8 nM) with oral activity. Lapatinib has antitumor activity and can be used to treat advanced or metastatic breast cancer with HER2 overexpression. | |||
T3710 | XMD16-5 | Tyrosinase , PPAR | |
XMD16-5 is a TNK2 inhibitor. TNK2 genomic amplification has been associated with late-stage or metastatic lung and prostate Ys. Overexpression of TNK2 promoted metastasis in a mouse model of breast Y. TNK2 signaling is d... | |||
T77374 | Ontuxizumab | MORAb-004 | Others |
Ontuxizumab (MORAb-004) is a monoclonal antibody targeting endomelanic acid with anti-tumor effects.Ontuxizumab is a potent IgG1/κ anti-endothelin (TEM-1 or CD248) monoclonal antibody for the treatment of metastatic mela... | |||
T2357 | GSK1059615 | GSK 1059615,GSK-1059615 | Apoptosis , PI3K , mTOR |
GSK1059615 has been used in trials studying the treatment of Lymphoma, Solid Tumours, Endometrial Cancer, Solid Tumor Cancer, and Metastatic Breast Cancer. | |||
T76857 | Anetumab | Others | |
Anetumab is a novel fully human anti-mesothelin IgG1 antibody that is a naked antibody to Anetumab ravtansine.Anetumab can be used to synthesize the antibody-activated molecule coupling, Anetumab ravtansine.Anetumab can ... | |||
T76828 | Sonepcizumab | LT 1009 | LPL Receptor |
Sonepcizumab (LT 1009) is a fully humanized monoclonal antibody against S1P. Sonepcizumab has anti-cancer activity and can be used to study metastatic renal cell carcinoma (mRCC) to prevent eye scarring after glaucoma fi... | |||
T29214 | ZEN-3694 | ZEN 3694,ZEN3694 | Epigenetic Reader Domain |
ZEN-3694 (ZEN 3694) is a bromo-structural domain extra-terminal inhibitor (BETi) with activity in androgen signaling inhibitor (ASI) resistance models and can be used in combination with enzalutamide to study metastatic ... | |||
T76750 | Cemiplimab | REGN-2810,SAR-439684 | Others |
Cemiplimab (Anti-Human PD-1) is a human monoclonal antibody against programmed cell death receptor 1 (PD-1) and a checkpoint inhibitor that blocks PD-1/PD-L1 mediated T-cell inhibition and can be used in metastatic cance... | |||
T77149 | Cobolimab | TSR-022,GSK4069889 | Others |
Cobolimab (TSR-022) is a potent monoclonal antibody to TIM-3. Cobolimab induces internalization of TIM-3 with an IC50 value of 0.4464 nM. Cobolimab has antitumor activity and can be used to study advanced/metastatic mela... | |||
T76890 | Petosemtamab | MCLA 158 | EGFR |
Petosemtamab (MCLA 158) is a highly potent monoclonal antibody against EGFR (Kd: 0.22 nM) and LGR5 (Kd: 0.86 nM). Petosemtamab promotes EGFR signaling disruption and receptor breakdown in LGR5+ cancer cells. Petosemtamab... | |||
T17228 | Sabizabulin | ABI-231,VERU-111 | Microtubule Associated |
Sabizabulin (ABI-231) is an effective and orally bioavailable inhibitor of α and β tubulin against panels of melanoma and prostate cancer cell lines. Sabizabulin inhibits tumor growth and metastatic phenotypes of cervica... | |||
T2283 | PX-12 | IV-2,PX12 | Thioredoxin |
PX-12 (PX12) (1-methylpropyl 2-imidazolyl disulfide) is a small-molecule inhibitor of Trx-1 (thioredoxin-1), stimulates apoptosis, down-regulates HIF-1α and vascular endothelial growth factor (VEGF) and inhibits tumor gr... | |||
T60616 | MPT0G211 | HDAC | |
MPT0G211 is a highly selective and orally active HDAC6 inhibitor (IC50=0.291 nM) that has neuroprotective effects and has shown anti-metastatic activity in human breast cancer cells. MPT0G211 has 1,000 times more affinit... | |||
T77434 | Vopratelimab | JTX 2011 | Others |
Vopratelimab (JTX-2011) is a selective humanized immunoglobulin G1-kappa monoclonal antibody that is a potent ICOS agonist. Vopratelimab has a high affinity for inducible T cell CO stimulating factors (ICOS), with an aff... | |||
TP1565L1 | Foxy-5 Ammonium Salt | Foxy-5 Ammonium Salt(881188-51-8 Free base) | Wnt/beta-catenin |
Foxy-5 Ammonium Salt is a WNT5A agonist, a mimetic peptide of WNT5A, a non-classical member of the Wnt family.Foxy-5 Ammonium Salt triggers cytoplasmic free calcium signaling without affecting β-catenin activation and in... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T1135 | Vitamin D3 | Cholecalciferol,Colecalciferol | Endogenous Metabolite |
Vitamin D3 (Cholecalciferol) , a naturally occurring form of vitamin D, activates an H305F/H397Y mutant vitamin D receptor (VDR). | |||
T5S0803 | Columbamine | Columbamin,Dehydroisocorypalmine | Others |
Columbamine (Columbamin) shows strong activity with IC5 48.1 μM.Columbamine exerts anti-proliferative and anti-vasculogenic effects on metastatic human osteosarcoma U2OS cells with low toxicity. | |||
T2543 | Cabazitaxel | XRP6258,RPR-116258A,TXD 258,taxoid XRP6258 | Microtubule Associated , Autophagy |
Cabazitaxel (taxoid XRP6258) is a taxane and antineoplastic agent which is currently used in the therapy of castration-resistant metastatic prostate cancer after failure of docetaxel. | |||
T7927 | β-Ionone | β-lonone | Apoptosis , Others |
β-Ionone (β-lonone) is an end-ring analog of β-carotenoids which widely distributed in fruit and vegetables,with anti-proliferative, anti-metastatic | |||
T20578 | Maclurin | Fustic extract,Morintannic acid,NSC 83240 | Free radical scavengers , Reactive Oxygen Species |
Maclurin (NSC-83240) is a phenolic component of mulberry twigs, exerts anti-metastatic effects. Maclurin effectively protects against OH-induced damages to DNA and MSCs and can be used in studies about the prevention of ... | |||
T1082 | Benzyl isothiocyanate | Benzoylthiocarbimide,Isothiocyanic Acid Benzoyl Ester | Apoptosis , Antibacterial , Antibiotic |
Benzyl isothiocyanate (Benzoylthiocarbimide) (BITC) is an isothiocyanate originally found in cruciferous vegetables. It shows immunomodulatory, anti-parasitic, antibiotic, antioxidative, anti-atherosclerotic, anti-angiog... | |||
T13741 | Isoviolanthin | Others | |
Isoviolanthin reduces the migratory and invasive capacities of TGF-β1-treated HCC cells without cytotoxic effects on normal live cells and has potential as a therapeutic agent for the treatment of advanced-stage metastat... | |||
T2P2923 | Stearic acid | Isostearic acid,Octadecanoic acid,Cetylacetic acid | Phosphatase , Endogenous Metabolite |
1. Stearic acid (Cetylacetic acid) can reduce metastatic tumor burden. 2. Stearic acid leads to dramatically reduced visceral fat likely by causing the apoptosis of preadipocytes. 3. Stearic acid and its derivatives have... | |||
T5S2358 | Dehydrocorydaline | Dehydrocorydalin,13-Methylpalmatine | BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy |
1. Dehydrocorydaline (13-Methylpalmatine) exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSC-LC cells. 2. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimeriz... | |||
T6S1369 | Vitexin | Apigenin-8-C-glucoside | Antioxidant |
1. Vitexin has antinociceptive and antispasmodic activities. 2. Vitexin exhibits a prominent first-pass effect. 3. Vitexin has antioxidant, antimyeloperoxidase, and α-glucosidase inhibitory activities. 4. Vitexin can eit... | |||
T5S0053 | Coptisine | Coptisin | Indoleamine 2,3-Dioxygenase (IDO) |
1. Coptisine (Coptisin) treatment increases cell viability based on its reversal effect on the enhanced activity of Indoleamine 2, 3-dioxygenase . 2. Coptisine treats myocardial I/R likely through suppressing myocardial ... | |||
TN1013 | Cucurbitacin D | Apoptosis | |
Cucurbitacin D, a triterpenoid isolated from Ecballium elaterium (L.), exhibits anticancer and antitumor activity, inhibits glucose uptake and lactate production in metastatic PrC, and induces inflammasome activation ind... | |||
TN1867 | Licoricidin | MMP , VEGFR , ROS | |
Licoricidin, is a potent anti-metastatic agent, which can markedly inhibit the metastatic and invasive capacity of malignant prostate cancer cells. | |||
T13472 | α-Carotene | Others | |
α-Carotene is isolated from yellow-orange and dark-green vegetables. α-Carotene is used as an anti-metastatic agent or as an adjuvant for anti-cancer drugs. | |||
TN3517 | Bisacurone | IL Receptor , IκB/IKK , TNF , NF-κB , ROS , Akt , PKC | |
Bisacurone has anti-oxidant, anti-inflammatory, and anti-metastatic activities, it may have a protective effect against ethanol-induced liver injury by suppressing hepatic oxidation and inflammation. | |||
TN1062 | Peonidin chloride | ERK , COX | |
Peonidin chloride has antioxidant activity. Peonidin has show potent inhibitory and apoptotic effects on cancer cells in vitro, notably metastatic human breast cancer cells. | |||
TN2813 | 23-deoxojessic acid | Others | |
23-Deoxojessic acid possesses strong cytotoxicity towards highly liver metastatic murine colon 26-L5 carcinoma cells, with ED50 values equal to or less than 6 microM. | |||
T16035 | Meleagrin | Others | |
Meleagrin, a roquefortine C-derived alkaloid produced by Penicillium fungi, serves as both a class of FabI inhibitors and a lead c-Met inhibitory entity for controlling c-Met-dependent metastatic and invasive breast mali... | |||
TN4352 | Jatamanvaltrate B | Others | |
Jatamanvaltrate B shows cytotoxicity against lung adenocarcinoma (A549), metastatic prostate cancer (PC-3M), colon cancer (HCT-8),and hepatoma (Bel7402) cell lines. | |||
TN4101 | Ganoderenic acid H | Others | |
Ganoderenic acid H is one compound of triterpenoids isolated from Ganoderma lucidum, triterpenoids exhibit a broad spectrum of anti-cancer properties, including anti-proliferative, anti-metastatic and anti-angiogenic act... | |||
TN5249 | Volvaltrate B | Others | |
Volvaltrate B shows cytotoxic activity against the lung adenocarcinoma (A549), metastatic prostate cancer (PC-3M), colon cancer (HCT-8), and hepatoma (Bel7402) cell lines, with IC50 values of 8.5, 2.0, 3.2, and 6.1 uM, r... | |||
TN3646 | Chlorovaltrate K | Others | |
Chlorovaltrate K shows moderate cytotoxicity against lung adenocarcinoma (A 549), metastatic prostate cancer (PC-3M), colon cancer (HCT-8) and hepatoma (Bel 7402) cell lines with IC50 values of 0.89-9.76 uM. | |||
T37055 | Cytostatin | ||
Cytostatin is a natural antitumor inhibitor of cell adhesion to extracellular matrix, blocking adhesion of B16 melanoma cells to laminin and collagen type IV in vitro (IC50s = 1.3 and 1.4 μg/ml, respectively) and B16 cel... | |||
TN4046 | Excisanin A | MMP , FAK , PARP , GSK-3 , NF-κB , Wnt/beta-catenin , Akt , Caspase , PI3K , Prostaglandin Receptor , JNK | |
ExcisaninA may be a potent inhibitor of AKT signaling pathway in tumor cells, it can inhibit invasion by suppressing MMP-2 and MMP-9 expression, it may be a potential anti-metastatic chemotherapeutic agent for the treatm... | |||
T40960 | Fibronectin | Integrin | |
Fibronectin is a macromolecular glycoprotein found in blood, connective tissue, and cell surfaces that serves as a biomarker for tissue damage.Fibronectin is recognized by the integrin family of surface receptors.Fibrone... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPJ-00778 | HER2/ERBB2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
HER2/ERBB2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 90-120 KDa and the accession number is P04626. | |||
TMPJ-00776 | HER2/ERBB2 Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 Cells |
HER2/ERBB2 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag. The predicted molecular weight is 120-140 KDa and the accession number is P04626. | |||
TMPJ-00777 | HER2/ERBB2 Protein, Human, Recombinant (aa 23-652, hFc) | Human | HEK293 Cells |
HER2/ERBB2 Protein, Human, Recombinant (aa 23-652, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 120-145 KDa and the accession number is P04626. | |||
TMPY-02030 | CD82 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetras... | |||
TMPY-04722 | DcR1/TRAILR3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
TNFRSF10C CNV in patients with CRC is associated with distant metastatic disease. A high frequency of CGI methylation in the TNFRSF10C promoter results in inactivation of the gene and enhancement of tumor growth in most ... | |||
TMPY-04830 | GAS6 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
The growth arrest-specific 6 gene (GAS6) is a member of the family of plasma vitamin K-dependent proteins, which are able to bind to phospholipids using an N-terminal gamma-carboxyglutamic acid domain. GAS6 is a vitamin ... | |||
TMPK-01299 | CEACAM5 Protein, Cynomolgus, Recombinant (aa 35-685, His) | Cynomolgus | HEK293 Cells |
Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) was identified as a metastatic driver. CEACAM5 overproduction enriched for an epithelial gene expression pattern and facilitated tumor outgrowth at meta... | |||
TMPY-03876 | PTGFRN Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
EWI-F, also known as PTGFRN, is inversely related to the loss of CD9. Its expression correlates with the metastatic status of hLT. EWI-F inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP rece... | |||
TMPK-00635 | CDCP1 Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss ... | |||
TMPY-02622 | Aldolase B Protein, Human, Recombinant (GST) | Human | E. coli |
The aldolase family members involved in metabolism and glycolysis are present in three isoforms: ALDOA, ALDOB, and ALDOC. Aldolases are differentially expressed in human tissues, and aberrant expression has been observed... | |||
TMPK-01010 | CDCP1 Protein, Mouse, Recombinant (His & Avi), Biotinylated | Mouse | HEK293 Cells |
Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss ... | |||
TMPK-01183 | CDCP1 Protein, Human, Recombinant (aa 30-368, His) | Human | HEK293 Cells |
Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss ... | |||
TMPK-01256 | CDCP1 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss ... | |||
TMPK-01182 | CDCP1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss ... | |||
TMPK-01255 | CDCP1 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated | Cynomolgus | HEK293 Cells |
Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss ... | |||
TMPK-01181 | CDCP1 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss ... | |||
TMPY-01122 | CGB5 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
The human CGB5 gene encodes chorionic gonadotropin (hCG)beta 5, which is aberrantly expressed in trophoblastic neoplasm and in some non-trophoblastic neoplasms. Fucntional studies observed that it involved tumor initiati... | |||
TMPK-00595 | Syndecan-1 Protein, Human, Recombinant (aa 23-254, His) | Human | HEK293 Cells |
Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still a major medical challenge. Syndecan-1 is one of the most important proteoglycans in the liver. Syndecan-1 is normally expressed on th... | |||
TMPK-01284 | Syndecan-1 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still a major medical challenge. Syndecan-1 is one of the most important proteoglycans in the liver. Syndecan-1 is normally expressed on th... | |||
TMPY-05250 | CLEC3A Protein, Mouse, Recombinant (His) | Mouse | Baculovirus Insect Cells |
C-type lectin domain family 3 member A (CLEC3A) is a poorly characterized protein belonging to the superfamily of C-type lectins. Elevated CLEC3A expression may correlate with breast IDC metastatic potential and indicate... | |||
TMPY-03982 | CGB5 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
The human CGB5 gene encodes chorionic gonadotropin (hCG)beta 5, which is aberrantly expressed in trophoblastic neoplasm and in some non-trophoblastic neoplasms. Fucntional studies observed that it involved tumor initiati... | |||
TMPK-00593 | Syndecan-1 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still a major medical challenge. Syndecan-1 is one of the most important proteoglycans in the liver. Syndecan-1 is normally expressed on th... | |||
TMPK-00594 | Syndecan-1 Protein, Human, Recombinant (aa 23-254, hFc) | Human | HEK293 Cells |
Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still a major medical challenge. Syndecan-1 is one of the most important proteoglycans in the liver. Syndecan-1 is normally expressed on th... | |||
TMPK-00201 | Syndecan-1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still a major medical challenge. Syndecan-1 is one of the most important proteoglycans in the liver. Syndecan-1 is normally expressed on th... | |||
TMPJ-00786 | ITGB1 Protein, Human, Recombinant (aa 21-728, His) | Human | HEK293 Cells |
Integrin β-1 (ITGB1) belongs to the integrin β chain family. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue ... | |||
TMPK-00728 | PSCA Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Gastric cancer is a deadly malignancy and is a prognostically unfavorable entity with restricted therapeutic strategies available. Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored cell s... | |||
TMPY-02384 | MTSS1 Protein, Human, Recombinant (aa1-250, His & MBP) | Human | E. coli |
MTSS1 (Metastasis suppressor 1), also known as Missing in metastasis (MIM), is a tissue-specific regulator of plasma membrane dynamics. MTSS1 is well described for its function as a metastasis suppressor gene and is expr... | |||
TMPK-00906 | PSCA Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Gastric cancer is a deadly malignancy and is a prognostically unfavorable entity with restricted therapeutic strategies available. Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored cell s... | |||
TMPY-03047 | Stathmin 1 Protein, Human, Recombinant (His) | Human | E. coli |
Stathmin1 (STMN1) is a cytosolic phosphoprotein that regulates cellular microtubule dynamics and is known to have oncogenic activity. STMN1 is a possible biomarker for paclitaxel sensitivity and poor prognosis in GC and ... | |||
TMPY-04765 | PKLR Protein, Human, Recombinant (His) | Human | E. coli |
Pyruvate kinase (PKLR) is a critical erythrocyte enzyme that is required for glycolysis and production of ATP. Pyruvate kinase deficiency (PKD) is the most frequent red blood cell enzyme abnormality of the glycolytic pat... | |||
TMPY-02276 | GPR56 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
ADGRG1 (Adhesion G Protein-Coupled Receptor G1, also known as GPR56) is a Protein Coding gene. GPR56 is a member of an adhesion G protein-coupled receptor family with a very long N-terminal stalk and seven transmembrane ... | |||
TMPY-04203 | RAB1B Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
RAB1B, a member of the RAS oncogene family, was significantly down-regulated in highly metastatic breast cancer cells. Moreover, down-regulation of RAB1B was also found to promote the proliferation and migration of TNBC ... | |||
TMPJ-00157 | CD82 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemoki... | |||
TMPY-01595 | PCBP1 Protein, Human, Recombinant (His) | Human | E. coli |
Poly(rC)-binding protein 1, also known as Heterogeneous nuclear ribonucleoprotein E1, Alpha-CP1, Nucleic acid-binding protein SUB2.3 and PCBP1, is a family member of heterogeneous nuclear ribonucleoproteins (hnRNPs) that... | |||
TMPJ-01137 | MIA Protein, Human, Recombinant (His) | Human | E. coli |
Melanoma Inhibitory Activity Protein (MIA) is an autocrine growth regulatory protein secreted from chondrocytes and malignant melanoma cells, which was the first discovered member of a family of secreted cytokines termed... | |||
TMPY-02386 | PTP4A2 Protein, Human, Recombinant (GST) | Human | E. coli |
PRL-2 (Protein-tyrosine phosphatase of regenerating liver 2), also known as PTP4A2 (Protein tyrosine phosphatase type IVA, member 2), is a member of PTP family and has an important function in controlling cell growth. PR... |
カタログ番号 | 製品名 | ||
---|---|---|---|
L2194 | Anti-Colorectal Cancer Compound Library | 1545 compounds | |
1545 compounds associated with colorectal cancer that can be used for high-throughput and high-content screening. | |||
L2196 | Anti-Ovarian Cancer Compound Library | 1867 compounds | |