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カタログ番号 | 製品名 | 別名 | ターゲット |
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T15485 | HJC0197 | cAMP , Ras | |
HJC0197 selectively blocks cAMP-induced Epac activation. HJC0197 is an effective exchange protein. Which straightly activated by cAMP (Epac) antagonist (IC50=5.9 μM for Epac2). | |||
T16263 | N6-Cyclopentyladenosine | UK-80882,CPA | Adenosine Receptor |
N6-Cyclopentyladenosine (CPA) is a selective agonist of the adenosine A1 receptor and can be used to mimic the action of the adenosine A1 receptor, with Ki's of 2.3 nM, 790 nM, and 43 nM for human A1, A2A, and A3 recepto... | |||
T21715 | BRD6688 | HDAC | |
BRD6688 is a selective HDAC2 inhibitor that acts by enhancing the learning and memory processes | |||
T11511 | Guanosine-5'-triphosphate disodium salt | 5'-GTP disodium salt | Others , Endogenous Metabolite |
Guanosine-5'-triphosphate disodium salt (5'-GTP disodium salt) is an enhancer of myogenic cell differentiation and an energy source for translation and other important cellular processes. | |||
T28506 | Rbin-2 | Phosphatase | |
Rbin-2 is a cell-permeable, potent, selective and reversible inhibitor of Midasin (Mdn1).Rbin-2 directly targets the AAA+ ATPase Midasin and inhibits eukaryotic ribosome production, making it a potent probe for the study... | |||
T21463 | Temozolomide Acid | TMZA | Others |
Temozolomide Acid (TMZA) is a metabolite of temozolomide (TMZ). Temozolomide processes anticancer activity in vitro. Temozolomide (TMZ) is an oral alkylating agent used to treat glioblastoma multiforme (GBM) and astrocyt... | |||
T19261 | D-Glucose-13C6 | D-(+)-Glucose-13C6,Glucose-13C6,Dextrose-13C6 | Endogenous Metabolite |
D-Glucose-13C6 (Dextrose-13C6) is an isotopic marker of D-Glucose, which can be used as a metabolic tracer for the study of metabolism-related diseases and metabolic processes of some substances in the body. | |||
T67579 | H-Glu(OMe)-OH | L-Glutamic acid 5-methyl ester | Amino Acids and Derivatives |
H-Glu(OMe)-OH is a glutamate derivative that is utilized in synthesizing various compounds and is related to immune and metabolic processes in the body. | |||
T64755 | Ammonium Chloride | Autophagy , Antifungal | |
Ammonium chloride acts as a small molecule autophagy inhibitor.Ammonium chloride is a pH-regulating, heteropolar compound that can cause intracellular alkalosis and metabolic acidosis, thereby affecting enzyme activity a... | |||
T14057 | 6-CFDA | 6-Carboxyfluorescein diacetate | Others |
6-CFDA (6-Carboxyfluorescein diacetate) is fluorescent polyanionic probe that used to measure changes in intracellular pH (pHi) and processes such as dendrimer aggregation and absorption. | |||
T15782 | Lp-PLA2-IN-1 | Lp-PLA2 inhibitor 1,Lp-PLA2 -IN-1 | Phospholipase |
Lp-PLA2-IN-1 (Lp-PLA2 inhibitor 1) suppresses Lp-PLA2 activity processes for their preparation. Lp-PLA2-IN-1 (Lp-PLA2 inhibitor 1) also inhibits to compositions containing them and to their use in the treatment of diseas... | |||
T78745 | Mtb-IN-2 | Antibiotic | |
Mtb-IN-2 is a small molecule compound of Mycobacterium tuberculosis (Mtb) with antimicrobial activity and low toxicity that interferes with methionine metabolism processes and can be used to study tuberculosis. | |||
T11267 | FASN-IN-1 | TVB-2460 | Fatty Acid Synthase |
FASN-in-1 is an effective, specific inhibitor of fatty acid synthase (FASN), a compound specifically designed to target and inhibit the activity of the enzyme involved in fatty acid synthesis, potentially disrupting fatt... | |||
T23371 | SMER3 | SMER 3 | Others , Ligand for E3 Ligase |
SMER3 is an inhibitor of the Skp1-Cullin-F-box (SCF)(Met30) ubiquitin ligase, a member of the SCF E3-ligase family, which regulates diverse cellular processes including transcription, cell-cycle control and immune respon... | |||
T6515 | Go6976 | Gö 6976 | PKC |
Go6976 is a small molecule inhibitor of protein kinase C (PKC). Go6976 has been widely used in biomedical research as a tool to study the role of PKC in various physiological and pathophysiological processes. | |||
T68455 | AP23846 | AP-23846 | Src |
AP23846 is a novel and potent Src family kinase inhibitor that reduces vascular endothelial growth factor and interleukin-8 expression and abrogates downstream angiogenic processes in human solid tumor cell lines. | |||
T4512 | Magnesium glycinate | magnesium 2-aminoacetate,Magnesium diglycinate | Others |
Magnesium glycinate (magnesium 2-aminoacetate) is a supplement that boost magnesium levels in people with a deficiency of the mineral. Magnesium is a vital nutrient for regulating many body processes, including muscle an... | |||
T60707 | Quinupramine | ||
Quinupramine is an orally active antidepressant that shows antidepressant activity associated with the central serotonin system, but not with the β-adrenergic system. Quinupramine is able to penetrate into the CNS and af... | |||
T3980 | Su1498 | Tyrphostin SU 1498,AG 1498 | VEGFR |
Su1498 (Tyrphostin SU 1498) is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEGFR2, aka FLK1; IC50 = 700 nM), having negligible activity at several other serine/threonine and tyrosine kinases.1,... | |||
T60278 | Tyrosinase-IN-2 | Tyrosinase | |
Tyrosinase-IN-2 (compound 67) is a potent inhibitor of tyrosinase, a copper-containing metalloenzyme pivotal for the catalytic step that limits the rate in melanin biosynthesis and enzymatic browning processes. This comp... | |||
T36983 | Cyclic-di-GMP disodium | Cyclic diguanylate,5GP-5GP disodium,3',5'-Cyclic diguanylic acid,Cyclic di-GMP (sodium salt),cyclic diguanylate disodium,c-di-GMP,c-di-GMP disodium | STING , Endogenous Metabolite |
Cyclic-di-GMP disodium (5GP-5GP disodium) is a bacterial second messenger and a STING agonist involved in a variety of prokaryotic processes including biofilm formation, motility, and cell cycle progression.Cyclic-di-GMP... | |||
T25360 | Eclazolast | RHC2871,RHC-2871,REV2871,REV 2871,RHC 2871 | Others |
Eclazolast (RHC 2871) is a lipophilic anti-allergic compound that inhibits mediator release in a mast cell model.Eclazolast inhibits extracellular secretion by affecting only the direct processes associated with Fc(epsil... | |||
T50115 | 3-phenoxy-8-azabicyclo[3.2.1]octane hydrochloride | Others | |
3-phenoxy-8-azabicyclo[3.2.1]octane hydrochloride is a synthetic compound belonging to the class of azabicyclooctanes. It is a potent and selective agonist of the dopamine D2 receptor and is widely used to study the mech... | |||
TP1168 | N-Formyl-Met-Leu-Phe-Lys | fMLFK | Others |
N-Formyl-Met-Leu-Phe-Lys (fMLFK) (fMLFK) is a peptide, acts as a potent and selective agonist of FPR1, with EC50s of 3.5 nM, 6.7 μM and 0.88 μM for FPR1, FPR2 and FPR2-D2817.32G, respectively.Chemotactic peptide (fMLFK) ... | |||
T78362 | Transglutaminase | TG | |
Transglutaminase (TG) is a thiolase that induces intermolecular cross-linking of proteins, by catalysing the formation of isopeptide bonds between the γ-carboxamide group of glutamine residues and the primary ε-amine gro... | |||
T15183 | Dynarrestin | Hedgehog/Smoothened | |
Dynarrestin is an inhibitor of cytoplasmic dyneins 1 and 2. Dynarrestin suppresses hedgehog (Hh)-dependent proliferation of neuronal precursors and tumor cells. It inhibits dynein 1-driven microtubule gliding in vitro pl... | |||
T60149 | 11β-HSD1-IN-11 | Dehydrogenase | |
11β-HSd1-in-11 is a potent and competitive inhibitor of 11-β-hydroxysteroid dehydrogenase 1 (11β-HSD1) IN rats and humans with IC50 values of 0.34 μM and 0.13 μM, respectively. 11β-Hsvd1-in-11 is a compound used as a che... | |||
T4251 | GJ103 sodium salt | ATM/ATR | |
GJ103 sodium salt is an active analog of GJ072, a read-through compound. It has been shown to reduce the surface tension of aqueous solutions, which makes it easier for molecules to move through the solution. It has also... | |||
T23709 | AlphaSYN-IN-NAB2 | alphaSYN inhibitor NAB2,alphaSYNINNAB2,alphaSYN-IN-NAB2,NAB2,alphaSYN inhibitor-NAB2 | |
alphaSYN-IN-NAB2, a neuron-protective agent, is a protein encoded by the NAB2 gene. NAB2 effectively and selectively protects a variety of cells from alpha-SYN toxicity. NAB2 promotes endosomal transport dependent on E3 ... | |||
T26616 | Ametryn | Cemerin,Doruplant,Topazol,Crisatrine,Gardopax,Gesapax | |
Ametryn is a methylthiotriazine based herbicide. Ametryn inhibits photosynthesis and other enzymatic processes. | |||
T23766 | AZD2836 | AZD 2836,A 831,A-831,A831,AZD-2836 | |
AZD2836 is an inhibitor of GT-1a and GT-1b that acts by interfering with host-mediated processes essential to viral replication. | |||
T13912 | Tacalcitol | 1,24(R)-Dihydroxyvitamin D3,1.alpha.,24R-Dihydroxyvitamin D3 | Others |
Tacalcitol (1,24(R)-Dihydroxyvitamin D3; 1.alpha.,24R-Dihydroxyvitamin D3) promotes normal bone development by regulating calcium. Tacalcitol modulates immunological and inflammatory processes. | |||
T19396 | L,L-Dityrosine | o,o'-Dityrosine | Others |
L,L-Dityrosine, a component found in the acid hydrolysates of various biological materials, such as insect cuticular resilin, plays a significant role in biochemical processes. | |||
T40507 | BTO-1 | ||
BTO-1 is a compound known as a Polo-like kinase (Plk) inhibitor, commonly employed for its effectiveness in regulating processes involving phosphorylation and dephosphorylation. | |||
T32537 | LAI-1 | LAI 1,Legionella autoinducer-1,Legionella autoinducer 1 | |
LAI-1 is a regulator of bacterial signaling, modulating gene regulation and cellular responses of eukaryotic cells (amoebae or macrophages) and a variety of processes including pathogen-host cell interactions. | |||
T39401 | Sphinganine 1-phosphate | D-erythro-Dihydrosphingosine 1-phosphate,Sphinganine 1-phosphate | |
Sphinganine 1-phosphate, also known as D-erythro-Dihydrosphingosine 1-phosphate, is a polar sphingolipid metabolite. It plays a crucial role in regulating various cellular processes including cell migration, differentiat... | |||
T23821 | BRD4884 | BRD-4884,BRD 4884 | |
BRD4884 is a selective inhibitor of HDAC2 that acts by enhancing the learning and memory processes. | |||
T80232 | Hrk BH3 | ||
Hrk BH3, a biologically active peptide comprising the BH3 domain of Hrk, exhibits functionality within cellular processes. | |||
T40491 | Luteinizing hormone (human) | ||
Luteinizing hormone (LH), a heterodimeric glycoprotein hormone synthesized by the pituitary gland, serves vital functions in human reproductive processes. | |||
T40714 | Xanthosine-5'-Triphosphate | 5'-XTP,Xanthosine-5'-Triphosphate | |
Xanthosine-5'-Triphosphate (5'-XTP), a nucleotide derived from the deamination of purine bases, plays a crucial role in various biological processes. | |||
T68720 | Plomestane | ||
Plomestane is a selective inhibitor of aromatization in human breast tissue and may provide a mechanism for controlling estrogen responsive processes. | |||
T40456 | 8-Bromoadenosine 5'-triphosphate tetrasodium | 8-Br-ATP tetrasodium,8-Bromoadenosine 5'-triphosphate tetrasodium | |
8-Bromoadenosine 5'-triphosphate tetrasodium (8-Br-ATP tetrasodium) is a tetrasodium ATP analogue, serving as a vital element for energy storage and metabolic processes in living organisms. ATP, a central component in vi... | |||
T72969 | Actinoquinol | ||
Actinoquinol, a compound effective in absorbing UVB radiation, plays a crucial role in protecting the human eye from photooxidative and other oxidative processes. | |||
T31940 | Glucosylgalactosylhydroxylysine | Hydroxylysine-glucose-galactose | |
Glucosylgalactosylhydroxylysine is a bone formation and bone resorption marker that is related to bone turnover processes during growth and development as well as metabolic bone diseases. | |||
T61247 | TRK-IN-16 | ||
TRK-IN-16 (WO2012034091A1, compound X-21) is a highly effective TRK inhibitor, targeting protein kinases that are integral to regulating cell growth, differentiation, and various cellular signal transduction processes. ... | |||
T34750 | Sut 8701 | Sut8701,Sut-8701 | |
Sut 8701 is a cholecystokinin analog that prevents cholinergic degeneration in the rat cerebral cortex following basal forebrain lesioning and can slow down the degenerative processes in Alzheimer's disease. | |||
T41036 | Sephadex LH 20 | ||
Sephadex LH 20 is a suitable medium for the isolation of natural compounds found in various sources, including red wine and pigments, aiding in their purification and extraction processes. | |||
T68557 | PF-376304 | ||
PF-376304 is a nonspecific PI3K inhibitor under development for anti-inflammatory indications. Phosphoinositide 3-kinase (PI3K) is an enzyme fundamental to the regulation of various metabolic processes. | |||
T38793 | THI0019 | THI0019 | |
THI0019 is a highly potent agonist of the integrin α4β1 (VLA-4) receptor, with an EC 50 range of 1-2 μM. It effectively promotes the adhesion of stem/progenitor cells. Furthermore, THI0019 successfully modulates adhesion... | |||
T38831 | Endoplasmic reticulum dye 1 | ||
Endoplasmic reticulum dye 1 is a highly effective live cell imaging agent used for detecting exocytotic events occurring at the plasma membrane. This compound exhibits minimal cytotoxicity and is resistant to photobleach... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T19125 | 3-Phenylbutyric acid | Others , Endogenous Metabolite | |
3-Phenylbutyric acid undergoes metabolism through initial oxidation processes involving both its benzene ring and side chain. It serves as an effective agent for the isolation of Rhodococcus rhodochrous PB1 from compost ... | |||
T4461 | 3,5-Diiodo-L-thyronine | Diiodothyronine | Thyroid hormone receptor(THR) , Endogenous Metabolite |
3,5-Diiodo-L-thyronine (Diiodothyronine) is an iodinated thyronine hormone that regulates gene activity affecting processes such as homeostasis, lipid metabolism and insulin resistance. | |||
T6323 | Oligomycin A | MCH 32 | ATPase , Antibiotic , Antifungal |
Oligomycin A (MCH 32) is an inhibitor of ATP synthase, inhibits oxidative phosphorylation and all the ATP-dependent processes occurring on the coupling membrane of mitochondria. | |||
T4897 | Inosine-5'-triphosphate trisodium salt | ITP,Inosine 5'-triphosphate trisodium salt | Others , Endogenous Metabolite |
Inosine-5'-triphosphate trisodium salt (ITP) is used in studies on the impact of deamination of ATP and GTP by various enzymes and chemical processes. Inosine-5'-triphosphate trisodium salt (ITP) may be used as a substra... | |||
T2881 | Crustecdysone | Commisterone,B-ecdysone,Commisterone,20-Hydroxyecdysone,Ecdysterone,B-ecdysone,Hydroxyecdysone | Others , Caspase , Endogenous Metabolite , Autophagy |
Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects. | |||
T5014 | Prostaglandin E2 | PGE2,Dinoprostone,Prostaglandin E2 (PGE2) | Endogenous Metabolite , Prostaglandin Receptor |
Prostaglandin E2 (PGE2) is a naturally occurring hormone involved in a variety of physiological processes in the body, including smooth muscle contraction and relaxation, regulation of vasodilatation and constriction, re... | |||
T1039 | Choline chloride | Biocolina,Biocoline,Hepacholine | AChR |
Choline chloride (Biocoline) is a basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in li... | |||
TN6891 | 1-Hexanol | hexan-1-ol | Others |
1-Hexanol (hexan-1-ol) is a natural product.1-Hexanol, a primary alcohol, is a surfactant that can be employed in industrial processes to enhance interfacial properties[1]. 1-Hexanol uncouples mitochondrial respiration b... | |||
T0332 | D-Sorbitol | Glucitol,Sorbitol,D-Glucitol | Others , Endogenous Metabolite |
D-Sorbitol (Sorbitol) is a polyhydric alcohol with about half the sweetness of sucrose. D-Sorbitol occurs naturally and is also produced synthetically from glucose. It was formerly used as a diuretic and may still be use... | |||
T6368 | Abscisic Acid | Abscisin II,Dormin,(+)-ABA,Abscisic Acid (Dormin) | Others , Proton pump , Endogenous Metabolite |
Abscisic Acid (Dormin) is a plant hormone, which is involved in many plant developmental processes, modulates ion homeostasis and metabolism, and inhibits germination and seedling growth. | |||
T20089 | ATP | Atipi,ATP disodium salt hydrate,Triphosphoric acid adenosine ester,Ara-ATP,Triphosphaden,Adenosine triphosphate;Ara-ATP,Adenosine triphosphate | Endogenous Metabolite |
ATP (Adenosine triphosphate) provides cellular energy, participates in overall energy balance, and maintains intracellular homeostasis. ATP can act as an extracellular signaling molecule through interactions with specifi... | |||
T3229 | Cytochalasin D | ATPase , p38 MAPK , Calcium Channel , Akt , PI3K | |
Cytochalasin D is an actin inhibitor, the removal of actin stress fibers is crucial for the chondrogenic differentiation. It may be an inhibitor of some fertilization processes such as sperm penetration or sperm head dec... | |||
T0326 | DL-Glutamine | Glutamin,DL-Gl,(±)-Glutamine,2-amino-4-carbamoylbutanoic acid | Ferroptosis , Amino Acids and Derivatives , Endogenous Metabolite |
DL-Glutamine (2-amino-4-carbamoylbutanoic acid), a non-essential amino acid, exists abundantly throughout the body and is participated in many metabolic processes. It is synthesized from glutamic acid and ammonia, and is... | |||
T4752 | 1-Aminocyclopropane-1-carboxylic acid | 1-Aminocyclopropanecarboxylic acid,1-Amino-1-carboxycyclopropane,ACC | Endogenous Metabolite , NMDAR |
1-Aminocyclopropane-1-carboxylic acid (ACC) is an intermediate in the synthesis of ethylene, the plant hormone responsible for biological processes ranging from seed germination to organ senescence. It is a small molecul... | |||
T4969 | Guanosine 5'-triphosphate trisodium salt | GTP Trisodium salt,5'-GTP trisodium salt | Endogenous Metabolite |
Guanosine 5'-triphosphate trisodium salt (5'-GTP trisodium salt) activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of se... | |||
T5065 | GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD | Monosodium-GMP,cGMP sodium salt,Cyclic GMP | PKA |
GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD (cGMP sodium salt) , also known as cGMP, is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, inc... | |||
T4809 | Pyrimidine | Metadiazine | Others , Endogenous Metabolite |
Pyrimidine (Metadiazine)s are heterocyclic, six-membered, nitrogen-containing carbon ring structures, with uracil, cytosine and thymine being the basal structures of ribose-containing nucleosides (uridine, cytidine, and ... | |||
TMM2618 | Gibberllin A7 | Gibberellin A7,Gibberllin 7 | Others |
Gibberllin A7 (Gibberllin 7) is important plant growth hormones that promote plant cell growth and elongation. Gebberillins promote rapid stem and root growth, induce mitotic division and initiate (break dormancy) and in... | |||
T13531 | Aflatoxicol | Aflatoxin R0 | Others |
Aflatoxin (Aflatoxin R0) is a mutagenic and carcinogenic mycotoxin derived from aflatoxin B1 through metabolic processes facilitated by Rhizopus spp. | |||
T19334 | Galactose 1-phosphate | Others | |
Galactose 1-phosphate, an intermediate substance in both galactose metabolism and nucleotide sugar processes, plays a crucial role in the biochemical pathways involved. | |||
TN6667 | Spinacetin | ||
Spinacetin has anti-inflammatory effects, it weakly inhibited nitric oxide production and reduced prostaglandin E2 levels to different extents. It shows the activities in preventing inflammatory processes, which might be... | |||
T83804 | 5-(3'-Hydroxyphenyl)-γ-Valerolactone | (3’-hydroxy)-PVL,δ-(3’-Hydroxyphenyl)-γ-VL,5-(3’-Hydroxyphenyl)-γ-VL,δ-(3’-Hydroxyphenyl)-γ-Valerolactone | |
5-(3'-Hydroxyphenyl)-γ-valerolactone, a metabolite resulting from the transformation of polyphenols such as (+)-catechin and (−)-epicatechin by gut microbiota, plays a significant role in biological processes. | |||
T40526 | ATP dipotassium | Adenosine5'-triphosphatedipotassium | |
ATP dipotassium (Adenosine 5'-triphosphate dipotassium) is a vital compound involved in energy storage and metabolism within living organisms. It plays a crucial role in supplying metabolic energy for driving pumps and a... | |||
T78501 | Glucoamylase | ||
Glucoamylase, an enzyme obtained from various sources such as plants, animals, and microorganisms, is utilized in industrial applications. It is extensively employed in starch saccharification processes and the brewing a... | |||
TN3351 | Aflatrem | GABA Receptor | |
Aflatrem is a tremorgenic mycotoxin with acute neurotoxic effects, a single low dose of aflatrem is able to induce degeneration of neuronal processes in hippocampal neurotransmitter systems. Aflatrem potentiates the gamm... | |||
T82750 | Cellooctaose | ||
Cellooctaose, an oligosaccharide comprising eight glucose units, serves as an economical polysaccharide substrate in fermentation processes to support the growth of Lactococcus lactis recombinant strains. Additionally, c... | |||
T81333 | Qianhucoumarin C | ||
Qianhucoumarin C, a coumarin derivative isolated from the roots of Peucedanum praeruptorum, exhibits potential medicinal properties such as anti-inflammatory, antioxidant, and anticancer effects. This compound plays a si... | |||
T39626 | Orotidine 5′-monophosphate | Orotidine monophosphate,Orotidylicacid,Orotidine 5′-monophosphate | |
Orotidine 5′-monophosphate, a pyrimidine ribonucleoside, functions as an endogenous metabolite in human, E. coli, and mouse processes. It serves as an intermediate in uridine monophosphate (UMP) biosynthesis and is utili... | |||
TN4490 | Manassantin B | ERK , BCL , p38 MAPK , TNF , NF-κB , JNK , STAT , Antifection | |
Manassantin B is a potent inhibitor of NF-κB activation by the suppression of transciptional activity of RelA/p65 subunit of NF-κB. It also possesses anti-EBV lytic replication activity. Manassantin B inhibits interleu... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPK-01243 | GDF-15 Protein, Rat, Recombinant (His) | Rat | E. coli |
Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GD... | |||
TMPJ-00090 | FGF-9 Protein, Human, Recombinant | Human | E. coli |
Fibroblast Growth Factor 9 (FGF-9) belongs to the Fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, inc... | |||
TMPY-06981 | IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli) | Human | E. coli |
IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli... | |||
TMPY-03382 | FGF-6 Protein, Human, Recombinant | Human | E. coli |
FGF6, also known as FGF-6, belongs to the fibroblast growth factor (FGF) family. Members of this family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, includi... | |||
TMPY-02869 | MMP-12 Protein, Human, Recombinant (catalytic domain) | Human | E. coli |
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, ... | |||
TMPY-03104 | FGF-17 Protein, Human, Recombinant | Human | E. coli |
FGF-13, also known as FGF17, belongs to the fibroblast growth factor (FGF) family. Members of this family show broad mitogenic and cell survival activities, and play a role in a variety of biological processes including ... | |||
TMPY-02907 | FGF-19 Protein, Human, Recombinant | Human | E. coli |
FGF19, also known as FGF-19, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, inclu... | |||
TMPY-01460 | ABHD4 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Abhydrolase domain containing 4 (ABHD4), also known as alpha/beta-hydrolase 4 (ABH4) , or lyso-N-acylphosphatidylethanolamine lipase, which belongs to the ABHD4/ABHD5 subfamily of peptidase S33 family. Abhydrolase domain... | |||
TMPJ-00327 | M-CSF/CSF1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Macrophage Colony-Stimulating Factors (m-csf) are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and th... | |||
TMPY-00541 | LON PROTEASE Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Lon protease, an ATP-dependent mitochondrial protease, is important in mitochondrial protein maintenance. Lon protease is a multifunctional enzyme, and its functions include the degradation of damaged proteins and natura... | |||
TMPY-04125 | PTP1B Protein, Human, Recombinant (His) | Human | E. coli |
PTP1B, also known as PTPN1, belongs to the protein-tyrosine phosphatase (PTP) family. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly c... | |||
TMPJ-00037 | FGF-2 Protein, Mouse, Recombinant | Mouse | E. coli |
FGF basic is one of 22 mitogenic proteins of the FGF family, which show 35-60% amino acid conservation. Unlike other FGFs, FGF acidic and basic lack signal peptides and are secreted by an alternate pathway. The 17 kDa mo... | |||
TMPJ-01467 | Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. OSM encodes a growth regulator, ... | |||
TMPY-02115 | R-Spondin 3/RSPO3 Protein, Human, Recombinant (aa 1-146, His) | Human | HEK293 Cells |
R-spondin 3 (RSPO3) is a member of the R-Spondin (RSPO) family in vertebrates that activate Wnt/beta-catenin signaling, plays a key role in these processes. The RSPO family of secreted Wnt modulators is involved in devel... | |||
TMPY-01061 | FGF-10 Protein, Human, Recombinant | Human | E. coli |
Fibroblast growth factor 10 (FGF10) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes... | |||
TMPY-01806 | CD9 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-02521 | HIST3H2A Protein, Human, Recombinant | Human | E. coli |
Histones are a complex family of highly conserved basic proteins responsible for packaging chromosomal DNA into nucleosomes. There are subtype diversities: H1, H2A, H2B, and H3 or H4. It has become more and more evident ... | |||
TMPY-04396 | C-ABL/ABL1 Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cy... | |||
TMPK-00677 | PKA/PRKACA Protein, Canine, Recombinant (His) | Canine | E. coli |
The cAMP-dependent protein kinase PKA is a well-characterized member of the serine-threonine protein AGC kinase family and is the effector kinase of cAMP signaling. As such, PKA is involved in the control of a wide varie... | |||
TMPJ-00587 | NRCAM Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Neuronal cell adhesion molecule(NRCAM) is a single-pass type I membrane protein ,containing 5 fibronectin type-III domains and 6 Ig-like C2-type (immunoglobulin-like) domains.It belongs to the immunoglobulin superfamily.... | |||
TMPH-00502 | TFF3 Protein, Canine, Recombinant (His & Myc) | Canine | E. coli |
Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen). | |||
TMPH-02243 | TFF3 Protein, Human, Recombinant (GST) | Human | E. coli |
Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen). | |||
TMPY-02965 | MMP-19 Protein, Human, Recombinant | Human | E. coli |
MMP19, also known as RASI-1, is a member of the peptidase M1A family. It contains 4 hemopexin-like domains and is expressed in the mammary gland, placenta, lung, pancreas, ovary, small intestine, spleen, thymus, prostate... | |||
TMPK-00776 | Complement factor I Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for controlling the complement-mediated processes. Complement factor I P... | |||
TMPH-02337 | Hydrophobin-1 Protein, Hypocrea jecorina, Recombinant (His & SUMO) | Hypocrea jecorina | E. coli |
Contributes to surface hydrophobicity, which is important for processes such as association of hyphae in reproductive structures, dispersal of aerial spores and adhesion of pathogens to host structures. Hydrophobin-1 Pro... | |||
TMPK-01379 | SEMA4D Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Semaphorin 4D (Sema4D) is a multifunctional protein widely expressed in an organism that plays an important role in the control of many physiological and pathological processes, including immunoregulation, neurogenesis, ... | |||
TMPH-02087 | STK38L Protein, Human, Recombinant (His) | Human | E. coli |
Involved in the regulation of structural processes in differentiating and mature neuronal cells. STK38L Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecula... | |||
TMPK-00727 | TNFSF12/TWEAK Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) is a well known multifunctional cytokine extensively distributed in cell types and tissues. Accumulating evidence has shown that TWEAK binding to the receptor ... | |||
TMPK-00404 | SEMA4D Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Semaphorin 4D (Sema4D) is a multifunctional protein widely expressed in an organism that plays an important role in the control of many physiological and pathological processes, including immunoregulation, neurogenesis, ... | |||
TMPH-02797 | NQO1 Protein, Mouse, Recombinant (His) | Mouse | P. pastoris (Yeast) |
The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-... | |||
TMPK-01361 | IGF2R Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. IGF2R Pro... | |||
TMPJ-00447 | MMP-3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue rem... | |||
TMPK-00093 | TIMP-1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Tissue inhibitor of metalloprotease-1 (TIMP-1) is a tissue inhibitor of matrix metalloproteinases (MMPs). It however exerts multiple effects on biological processes, such as cell growth, proliferation, differentiation an... | |||
TMPY-04623 | PRRG2 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
The genes encoding a family of proteins termed proline-rich gamma-carboxyglutamic acid (PRRG) proteins were identified and characterized more than a decade ago. These novel membrane proteins have an extracellular gamma-c... | |||
TMPH-02313 | RPGR Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Could be a guanine-nucleotide releasing factor. Plays a role in ciliogenesis. Probably regulates cilia formation by regulating actin stress filaments and cell contractility. Plays an important role in photoreceptor integ... | |||
TMPK-00156 | DKK1 N terminal Domain Protein, Human, Recombinant (hFc & Avi) | Human | HEK293 Cells |
Dickkopf-1 (Dkk1), the founding and best-studied member of the Dkk family, functions as an antagonist of canonical Wnt/β-catenin. Dkk1 is considered to play a broad role in a variety of biological processes. DKK1 N termi... | |||
TMPH-03166 | Elastase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) | Pseudomonas aeruginosa | E. coli |
Cleaves host elastin, collagen, IgG, and several complement components as well as endogenous pro-aminopeptidase. Autocatalyses processing of its pro-peptide. Processes the pro-peptide of pro-chitin-binding protein (cbpD)... | |||
TMPK-00158 | DKK1 N terminal Domain Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 Cells |
Dickkopf-1 (Dkk1), the founding and best-studied member of the Dkk family, functions as an antagonist of canonical Wnt/β-catenin. Dkk1 is considered to play a broad role in a variety of biological processes. DKK1 N termi... | |||
TMPH-02882 | NQO2 Protein, Mouse, Recombinant (His) | Mouse | P. pastoris (Yeast) |
The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma... | |||
TMPH-02650 | FCMR/FAIM3 Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory... | |||
TMPJ-01393 | PGCP Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Carboxypeptidase Q (Cpq) is a member of the peptidase M28 family. PGCP is involved in a number of fundamental biological processes such as the hydrolysis of circulating peptides, catalyzing the hydrolysis of dipeptides w... | |||
TMPJ-00784 | Alkaline Phosphatase Protein, Human, Recombinant (aa 23-506, His) | Human | HEK293 Cells |
ALPP is a membrane protein and exits as a homodimer. ALPP is expressed only in normal term placenta, endocervix and fallopian tube and also in ovarian and proximal gastrointestinal tumors. It has been shown to play a rol... | |||
TMPK-00517 | GAS6 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Growth arrest-specific 6, also known as Gas6, is a human gene encoding the Gas6 protein, which was originally found to be upregulated in growth-arrested fibroblasts. Gas6 is a member of the vitamin K-dependent family of ... | |||
TMPJ-00362 | MMP-2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
72 kDa type IV collagenase also known as matrix metalloproteinase-2 (MMP-2) and gelatinase A is an enzyme that in humans is encoded by the MMP2 gene.It belongs to the matrix metalloproteinase (MMP) family. Matrix metallo... | |||
TMPH-02730 | ITIH2 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyal... | |||
TMPY-02246 | HB-EGF Protein, Human, Recombinant | Human | Baculovirus Insect Cells |
Heparin-binding EGF-like growth factor (HBEGF), a member of the EGF family of growth factors, exerts its biological activity through activation of the EGFR and other ErbB receptors. Soluble mature HBEGF is proteolyticall... | |||
TMPK-00868 | Notch 4 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
The Notch signaling pathway is important for cell-cell communication; it is involved in gene regulation mechanisms that control multiple cell differentiation processes during embryonic and adult life. Notch-4 expression ... | |||
TMPK-01023 | Complement factor I Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for controlling the complement-mediated processes. Complement factor I P... | |||
TMPK-01354 | IGF2R Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. IGF2R Pro... | |||
TMPH-01254 | DNM1 Protein, Human, Recombinant (His) | Human | E. coli |
Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocy... | |||
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カタログ番号 | 製品名 | ||
---|---|---|---|
L9400 | PPI Inhibitor Library | 485 compounds | |
A unique collection of 485 PPI-related compounds for drug screening; | |||
L3500 | Histone Modification Compound Library | 469 compounds | |
A unique collection of 469 histone modification related compounds for high throughput screening (HTS) and high content screening (HCS); | |||
L1200 | Epigenetics Compound Library | 953 compounds | |
Well-chosen 953 compounds related to epigenetic regulation for research in epigenetics, high throughput screening (HTS) and high content screening (HCS) for new drugs; | |||
L2800 | Serotonin Receptor-Targeted Compound Library | 268 compounds | |
A unique collection of 268 compounds targeting serotonin receptors for high throughput screening and high content screening; | |||
L4660 | Anti-Nervous System Disease Library | 1246 compounds | |
Well-chosen 1246 compounds with unique structures targeting nervous system; | |||
L1400 | MAPK Inhibitor Library | 365 compounds | |
A unique collection of 365 compounds targeting MAPK signaling for drug discovery in MAPK related diseases; | |||
L1610 | FDA-Approved Kinase Inhibitor Library | 263 compounds | |
A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening. | |||
L8700 | Ferroptosis Compound Library | 779 compounds | |
A unique collection of 779 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study; | |||
L3700 | JAK-STAT Compound Library | 252 compounds | |
A unique collection of 252 JAK/STAT signaling targeted compounds for high throughput and high content screening; | |||
L2500 | Human Endogenous Metabolite Library | 499 compounds | |
A collection of 499 selected human endogenous metabolites for high throughput and high content screening. | |||
L1110 | Microtubule-Targeted Compound Library | 142 compounds | |
A unique collection of 142 microtubule-targeted compounds can be used in HTS and HCS; | |||
L3300 | Histamine & Melatonin Receptor-Targeted Compound Library | 153 compounds | |
A unique collection of 153 compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS) for new drugs; | |||
L4300 | Wnt/Hedgehog/Notch Compound Library | 237 compounds | |
A unique collection of 237 Wnt/Hedgehog/Notch signaling targeted compounds for high throughput and high content screening; | |||
L2550 | Glutamine Metabolism Compound Library | 565 compounds | |
A unique collection of 565 glutamine metabolism related compounds can be used for high throughput screening (HTS) and high content screening (HCS), and also is an effective tool for research in glutamine metabolism and ... | |||
L5300 | Mitochondria-Targeted Compound Library | 812 compounds | |
A unique collection of 812 promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine; | |||
L3800 | NF-κB Signaling Compound Library | 729 compounds | |
A unique collection of 729 compounds targeting NF-κB signaling for high throughput screening and high content screening; | |||
L6000 | Natural Product Library for HTS | 4533 compounds | |
A unique collection of 4533 pure natural products and their derivatives with known biological activity for drug discovery, pharmacological study, stem cell differentiation, fingerprint study and quality research, and can... | |||
L2570 | Human Metabolite Library | 4454 compounds | |
A unique collection of 4454 human metabolites for high-throughput, high-content screening. | |||
L2010 | Highly Selective Inhibitor Library | 575 compounds | |
L7600 | Chemokine Inhibitor Library | 59 compounds | |
A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening; | |||
L9840 | Anti-Alzheimer's Disease Compound Library | 986 compounds | |
A unique collection of 986 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS. | |||
L6400 | Marine Natural Product Library | 144 compounds | |
A unique collection of 144 marine natural products for high throughput screening (HTS) and high content screening (HCS); |