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Search Results for " Cytotoxicity "

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255

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64

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TargetMolキット

カタログ番号 製品名 別名 ターゲット
T9925 Ofatumumab Others
Ofatumumab is a fully human monoclonal antibody to CD20 which appears to inhibit early-stage B lymphocyte activation
T9918 Daratumumab Others
Daratumumab is a human monoclonal antibody that targets CD38 a cell surface protein that is overexpressed on multiple myeloma MM) cells.
T0840 Methimazole Tapazole,Thiamazole Thyroid hormone receptor(THR)
Methimazole (Thiamazole) is an antithyroid compound with significant hepatotoxicity and is often used in the study of hyperthyroidism.
T3594 ML346 HSP
ML346 is a novel activator of Hsp70.
T7057 Methylstat Histone Demethylase , Others
Methylstat is a methyl ester prodrug of a Jumonji C domain-containing histone demethylase (JMJD) inhibitor that has favorable cell permeability. The free acid of methylstat inhibits JMJD2A, JMJD2C, JMJD2E, PHF8, and JMJD...
T2496 (Z)-Semaxinib SU5416 VEGFR
(Z)-Semaxinib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor (IC50: 1.23 μM), 20-fold more selective for VEGFR over PDGFRβ, no inhibition for FGFR, InsR, and EGFR. (Z)-Semaxinib is a quinolone derivative w...
T5399 GeA-69 PARP
GeA-69 (GeA69) is a selective and allosteric PARP14 macrodomain 2 (MD2) inhibitor (Kd: 0.86 μM in ITC assays).
T1753 D-64131 Microtubule Associated
D-64131 is a tubulin polymerization inhibitor with an IC50 value of 0.53 μM.
T8320 J14 J-14 Reactive Oxygen Species
J-14 is an inhibitor of reversible sulfiredoxin(IC50 : 8.1 μM). J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin, leading to cytotoxicity and cancer cell death
T4337 PCI 29732 PCI29732,PCI-29732 Others , BCRP , BTK
PCI 29732 is a selective and irreversible Btk inhibitor with IC50 of 8.2 nM in a FRET based biochemical enzymology assay.
T13951 UCB-9260 TNF
UCB-9260 inhibits TNF signaling by stabilizing an asymmetric form of the trimer.
T8235 L-732138 Neurokinin receptor
L-732138 is a potent and competitive antagonist of neurokinin-1 (NK-1) receptor(IC50 : 2.3 nM)
T12871 Talmapimod SCIO-469 p38 MAPK
Talmapimod (SCIO-469) is an selective, orally active, and ATP-competitive p38α inhibitor with IC50 of 9 nM and 90 nM for p38α and p38β, respectively. Talmapimod exhibits at least 2000-fold selectivity over a panel of 20 ...
T6912 NU1025 NSC 696807 PARP
NU1025 (NSC-696807) is a potent PARP inhibitor with IC50 of 400 nM.
TP1444 Magainin 2 Antibacterial , Antibiotic , Antifungal
Magainin II is a member of the antimicrobial peptides family
T4517 L189 DNA , DNA/RNA Synthesis
L189 is a human DNA ligase inhibitor, inhibits hLigI/III/IV (IC50: 5/9/5 μM).
T6612 NU6027 ATM/ATR , DNA-PK , CDK
NU6027 is a potent ATR/CDK inhibitor, inhibits CDK1/2, ATR and DNA-PK with Ki of 2.5 μM/1.3 μM, 0.4 μM and 2.2 μM, enter cells more readily than the 6-aminopurine-based inhibitors.
T20038 2-Fluoroadenine NSC-27364,NSC 27364,NSC27364 DNA/RNA Synthesis
2-Fluoroadenine (NSC-27364) has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.
T2324 Darunavir TMC114 HIV Protease
Darunavir (TMC114) is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS. Due to the emergence of ANTIVIRAL DRUG RESISTANCE when used alone, it is administered in combination with other AN...
T8492 BO-264 Apoptosis , FGFR
BO-264 is a highly potent and orally active inhibitor of transforming acidic coiled-coil 3 (TACC3, IC50 of 188 nM and a Kd of 1.5 nM).
T8756 KRAS inhibitor-9 DUN09716 Apoptosis , Ras
KRAS inhibitor-9 (DUN09716) is a potent KRAS inhibitor with Kd of 92 μM that blocks the formation of GTP-KRAS and downstream activation of KRAS. KRAS inhibitor-9 causes G2/M cell cycle arrest and induces apoptosis. KRAS ...
T5363 Tempo 2,2,6,6-Tetramethylpiperidinooxy Free radical scavengers , Reactive Oxygen Species , DNA/RNA Synthesis , Mitochondrial Metabolism
Tempo (2,2,6,6-Tetramethylpiperidinooxy) has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as a structural probe in electron spin resonance spectroscopy.
T6120 Pralatrexate Folotyn,10-Propargyl-10-deazaaminopterin Apoptosis , DHFR , Antifolate , TAM Receptor
Pralatrexate (10-Propargyl-10-deazaaminopterin) is a folate analogue inhibitor of dihydrofolate reductase (DHFR) exhibiting high affinity for reduced folate carrier-1 (RFC-1) with antineoplastic and immunosuppressive act...
T7055 Bz-RS-ISer(3-Ph)-Ome Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate Others , HIV Protease
Bz-RS-ISer(3-Ph)-Ome (Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate) is a paclitaxel derivative that inhibits the HSV replication cycle at low cytotoxicity, blocks mitosis in Vero cells, affects the size o...
T9150 SCR130 1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo- Apoptosis , Others , DNA/RNA Synthesis
SCR130 (1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-) is enzyme inhibition, antiproliferative effects and antifungal activity.
T13238 Tyrphostin AG1433 SU1433,AG1433 VEGFR , PDGFR
T22381 Antimalarial agent 14 4-hydroxy-3-phenyl-naphthalene-1,2-dione,2-Hydroxy-3-phenyl-1,4-naphthoquinone Others
Antimalarial agent 14 (NSC-102533) is a bioactive chemical.
T2241 Alisertib MLN 8237 Apoptosis , Aurora Kinase , Autophagy
Alisertib (MLN 8237) is a specific Aurora A inhibitor (IC50: 1.2 nM). The selectivity of Alisertib(MLN 8237) is >200-fold higher for Aurora A than Aurora B.
T4297 Flibanserin BIMT-17BS,Girosa,BIMT-17 Dopamine Receptor , 5-HT Receptor
Flibanserin (Girosa) is a serotonergic antidepressant used to treat hypoactive sexual desire disorder. Flibanserin has been associated with a low rate of minor serum aminotransferase elevations during treatment but has n...
T2514 Linifanib ABT-869,RG3635,AL-39324 Apoptosis , c-Fms , VEGFR , FLT , CSF-1R , PDGFR , c-Kit , Autophagy
Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and PDGFRβ (IC50: 66 nM). Linifanib may exhibit potent antiprolife...
T14848 C 87 Others , TNF
C 87 is a small-molecule TNF-α inhibitor. C 87 directly binds to TNFα, potently inhibits TNF-α-induced cytotoxicity (IC50 = 8.73 μM), and effectively blocks TNF-α-triggered signaling activities.
T7082 HDAC8-IN-1 HDAC
MDK-7933 (HDAC8-IN-1) is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines. MDK-7933 shows antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5). HDAC8-IN-1 exhibits ...
T7969 Dipyrithione Others
Dipyrithione appears to have novel cytotoxicity and potent broad-spectrum antitumor activity
T73588 8-(4-iodophenyl)-1,3,5,7-tetramethyl BODIPY
8-(4-iodophenyl)-1,3,5,7-tetramethyl BODIPY is a novel BODIPY fluorescent dye for the treatment of cytotoxicity.
T16557 PNU-159682 Topoisomerase
PNU-159682 is a highly effective metabolite of the anthracycline nemorubicin. PNU-159682 has outstanding cytotoxicity. PNU-159682 is an effective ADCs cytotoxin.
T9903 Avelumab PD-1/PD-L1
Avelumab is a fully human IgG1 anti-PD-L1 monoclonal antibody. Avelumab shows potential antibody-dependent cell-mediated cytotoxicity.
T6256 YYA-021 YYA 021 gp120/CD4 , HIV Protease
YYA-021 inhibits HIV entry, with high anti-HIV activity and low cytotoxicity.
T28607 Rocepafant LAU 8080,LAU8080,BN 50730,LAU-8080,BN50730,BN-50730 Platelet aggregation
Rocepafant (LAU8080) is a platelet-activating factor (PAF) antagonist that attenuates hypoxic-ischemic brain damage in neonatal rats.Rocepafant inhibits tumor necrosis factor-Afa-mediated cytotoxicity in mouse L929 tumor...
T7293 EC330 Others
EC330, a novel steroidal LIF inhibitor showed cytotoxicity in various cancer cell lines and NCI-60 cell line panel at low nano-molar range.
T7323 BCI-215 Phosphatase
BCI-215 causes selective cancer cell cytotoxicity in part through non-redox-mediated activation of MAPK signaling
T40063 CBR-470-1 Nrf2
CBR-470-1 is a potent inhibitor of glycolytic phosphoglycerate kinase 1 (PGK1) that activates NRF2 by increasing methylglyoxal levels. CBR-470-1 is a non-covalent Nrf2 activator with neuroprotective activity that protect...
T83643 4-Methylumbelliferyl heptanoate 4-Methylumbelliferyl enanthate
4-Methylumbelliferyl heptanoate (4-Methylumbelliferyl enanthate) is a lipase fluorescent substrate that detects cell-mediated cytotoxicity and cell proliferation.
T2069L TH287 hydrochloride DNA/RNA Synthesis , MTH1
TH287 is a selective MTH1 inhibitor(IC50 : 0.8 nM). It causees incorporation of oxidized dNTPs in cancer cells, leading to DNA damage, cytotoxicity and therapeutic responses in patient-derived mouse xenografts.
T15009 Elacytarabine 5'-Oleoyl cytosine arabinoside,5'-O-(Elaidoyl) 1-beta-D-arabinofuranosylcytosine,5'-Oleoyl cytarabine,CP 4055 Others
Elacytarabine (M7594 0037), a lipid-conjugated derivative of the nucleoside analog cytarabine, is an antineoplastic drug. It has cytotoxicity in solid tumors.
TNU0031 5-Hydroxyuridine OHUrd Nucleoside Antimetabolite/Analog
5-Hydroxyuridine (OHUrd) is a purine nucleoside analogue with potential antitumour activity, showing cytotoxicity against human colon adenocarcinoma cell lines.
T65309 S-Methyl methanesulfonothioate Antibacterial
S-Methyl methanesulfonothioate is a biological raw material with cytotoxicity and potential antimicrobial activity for the study of Pseudomonas aeruginosa infections.
T8622 ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE Others
ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE is useful for preparation and study of hypoxia-selective cytotoxicity of indolequinone antitumor agents.
T29857 Alethine β-Alethine TNF
Alethine (β-Alethine) is a small molecule compound with antitumour activity and is used to treat tumours and infections. The alethine-induced up-regulation of TNFα increases the cytotoxicity of T cells.
T4412 Roquinimex Linomide,LS2616,FCF89,ABR212616 TNF
Roquinimex (FCF89) (Linomide) is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity; inhibits angiogenesis and reduces the secretion of TNF alpha.
T60041 N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide Microtubule Associated
N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide, a TAU cytotoxicity inhibitor, inhibits LDH leakage of M17-TAU P301L cells with EC50 of 325nM.

Compounds

Ofatumumab
T9925
Synonym:
Target: Others
Daratumumab
T9918
Synonym:
Target: Others
Methimazole
T0840
Synonym: Tapazole,Thiamazole
Target: Thyroid hormone receptor(THR)
ML346
T3594
Synonym:
Target: HSP
Methylstat
T7057
Synonym:
Target: Histone Demethylase, Others
(Z)-Semaxinib
T2496
Synonym: SU5416
Target: VEGFR
GeA-69
T5399
Synonym:
Target: PARP
D-64131
T1753
Synonym:
Target: Microtubule Associated
J14
T8320
Synonym: J-14
Target: Reactive Oxygen Species
PCI 29732
T4337
Synonym: PCI29732,PCI-29732
Target: Others, BCRP, BTK
UCB-9260
T13951
Synonym:
Target: TNF
L-732138
T8235
Synonym:
Target: Neurokinin receptor
Talmapimod
T12871
Synonym: SCIO-469
Target: p38 MAPK
NU1025
T6912
Synonym: NSC 696807
Target: PARP
Magainin 2
TP1444
Synonym:
Target: Antibacterial, Antibiotic, Antifungal
L189
T4517
Synonym:
Target: DNA, DNA/RNA Synthesis
NU6027
T6612
Synonym:
Target: ATM/ATR, DNA-PK, CDK
2-Fluoroadenine
T20038
Synonym: NSC-27364,NSC 27364,NSC27364
Target: DNA/RNA Synthesis
Darunavir
T2324
Synonym: TMC114
Target: HIV Protease
BO-264
T8492
Synonym:
Target: Apoptosis, FGFR
KRAS inhibitor-9
T8756
Synonym: DUN09716
Target: Apoptosis, Ras
Tempo
T5363
Synonym: 2,2,6,6-Tetramethylpiperidinooxy
Target: Free radical scavengers, Reactive Oxygen Species, DNA/RNA Synthesis, Mitochondrial Metabolism
Pralatrexate
T6120
Synonym: Folotyn,10-Propargyl-10-deazaaminopterin
Target: Apoptosis, DHFR, Antifolate, TAM Receptor
Bz-RS-ISer(3-Ph)-Ome
T7055
Synonym: Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate
Target: Others, HIV Protease
SCR130
T9150
Synonym: 1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-
Target: Apoptosis, Others, DNA/RNA Synthesis
Tyrphostin AG1433
T13238
Synonym: SU1433,AG1433
Target: VEGFR, PDGFR
Antimalarial agent 14
T22381
Synonym: 4-hydroxy-3-phenyl-naphthalene-1,2-dione,2-Hydroxy-3-phenyl-1,4-naphthoquinone
Target: Others
Alisertib
T2241
Synonym: MLN 8237
Target: Apoptosis, Aurora Kinase, Autophagy
Flibanserin
T4297
Synonym: BIMT-17BS,Girosa,BIMT-17
Target: Dopamine Receptor, 5-HT Receptor
Linifanib
T2514
Synonym: ABT-869,RG3635,AL-39324
Target: Apoptosis, c-Fms, VEGFR, FLT, CSF-1R, PDGFR, c-Kit, Autophagy
C 87
T14848
Synonym:
Target: Others, TNF
HDAC8-IN-1
T7082
Synonym:
Target: HDAC
Dipyrithione
T7969
Synonym:
Target: Others
8-(4-iodophenyl)-1,3,5,7-tetramethyl BODIPY
T73588
Synonym:
Target:
PNU-159682
T16557
Synonym:
Target: Topoisomerase
Avelumab
T9903
Synonym:
Target: PD-1/PD-L1
YYA-021
T6256
Synonym: YYA 021
Target: gp120/CD4, HIV Protease
Rocepafant
T28607
Synonym: LAU 8080,LAU8080,BN 50730,LAU-8080,BN50730,BN-50730
Target: Platelet aggregation
EC330
T7293
Synonym:
Target: Others
BCI-215
T7323
Synonym:
Target: Phosphatase
CBR-470-1
T40063
Synonym:
Target: Nrf2
4-Methylumbelliferyl heptanoate
T83643
Synonym: 4-Methylumbelliferyl enanthate
Target:
TH287 hydrochloride
T2069L
Synonym:
Target: DNA/RNA Synthesis, MTH1
Elacytarabine
T15009
Synonym: 5'-Oleoyl cytosine arabinoside,5'-O-(Elaidoyl) 1-beta-D-arabinofuranosylcytosine,5'-Oleoyl cytarabine,CP 4055
Target: Others
5-Hydroxyuridine
TNU0031
Synonym: OHUrd
Target: Nucleoside Antimetabolite/Analog
S-Methyl methanesulfonothioate
T65309
Synonym:
Target: Antibacterial
ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE
T8622
Synonym:
Target: Others
Alethine
T29857
Synonym: β-Alethine
Target: TNF
Roquinimex
T4412
Synonym: Linomide,LS2616,FCF89,ABR212616
Target: TNF
N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide
T60041
Synonym:
Target: Microtubule Associated
1 2 3 4 5 6 7 8 9 10
カタログ番号 製品名 別名 ターゲット
T37341 N-Acetyltyramine Antibacterial
N-acetyltyramine is a metabolite of the biogenic amine tyramine . It enhances cytotoxicity of doxorubicin in resistant P388 murine leukemia cells with an IC50 value of 0.13 μg/ml compared with an IC50 value of 0.48 μg/ml...
TN1807 Isoverticine BCL , Caspase
Isoverticine exhibits significant antitussive, expectorant and anti-inflammatory activities, it also displays significant cytotoxicity.
T11685 Isolongifolene (-)-Isolongifolene Apoptosis , Others
Isolongifolene ((-)-Isolongifolene), a tricyclic sesquiterpene isolated from Murraya koenigii, exhibits antioxidant, anti-inflammatory, anticancer, and neuroprotective properties. It mitigates Rotenone-induced oxidative ...
T8205 Norwogonin 5,7,8-Trihydroxyflavone Virus Protease
Norwogonin (5,7,8-Trihydroxyflavone), isolated from Scutellaria baicalensis Georgi, possesses antiviral activity against Enterovirus 71 (IC50: 31.83 μg/ml).
TN1103 Diphyllin ATPase , Proton pump , Influenza Virus , HIV Protease
Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling.
T4034 Solamargine Solamargin,δ-Solanigrine Apoptosis , p38 MAPK , P-gp , STAT
Solamargine (δ-Solanigrine) is a major steroidal alkaloid glycoside extracted from a traditional Chinese medicine herb, Solanum nigrum L. (SNL); has been shown to inhibit growth and induce apoptosis of various cancer cel...
T0626 Uric Acid 2,6,8-Trioxopurine,2,6,8-Trioxypurine,2,6,8-Trihydroxypurine,Lithic acid,Urate Reactive Oxygen Species , Endogenous Metabolite , Phosphorylase
Uric Acid (Lithic acid) is an oxidation product of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE ...
T17155 Trabectedin Ecteinascidin 743,ET-743 Apoptosis , Reactive Oxygen Species
Trabectedin (Ecteinascidin 743) has potent antitumor activity and the potential for soft tissue sarcoma and ovarian cancer research. Trabectedin inhibits cell growth of MX-1, MCF7 and MCF7/DXR cells with IC50 values of 0...
T4970 LANOSTEROL 3β-Hydroxy-8,24-lanostadiene,8,24-Lanostadien-3β-ol Endogenous Metabolite
Lanosterol (3β-Hydroxy-8,24-lanostadiene) is a tetracyclic triterpenoid which is the compound from which all steroids are derived.
TN6924 Anhydrosafflor yellow B (2S,3S)-6,7-dihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-2-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-3-{2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-oxo-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]cyclohexa-1,4-dien-1,AHSYB Others
Anhydrosafflor yellow B ((2S,3S)-6,7-dihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-2-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-3-{2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-oxo-3-[(2R,3R,4S,5S,6R)-3,4,...
T11354 Gambogellic acid
Gambogellic acid is an xanthone compound obtained from Garcinia cambogia and processed Gambog, is antitumor activity and cytotoxicity.
T2907 Tanshinone I Tanshinone A Phospholipase
Tanshinone I (Tanshinone A), an active principle isolated from the herbal medicine Salvia miltiorrhiza, displays cytotoxicity against tumor cells.
T5S0246 Pseudoprotodioscin Others , Fatty Acid Synthase
1. Pseudoprotodioscin has moderate cytotoxicity.
TN7032 4'-O-Methylpyridoxine 4-methoxymethylpyridoxine,Ginkgotoxin Antioxidant
4'-O-Methylpyridoxine (MPN) is a vitamin-like compound discovered from Ginkgo biloba with antioxidant activity and cytotoxicity.
TN6444 Cyclo(Tyr-Leu) Antifungal
T3S1628 Vitexin-4''-O-glucoside Vitexin -4''-O-glucoside Others
Vitexin-4''-O-glucoside (Vitexin -4''-O-glucoside) could effectively protect ECV-304 cells against cytotoxicity induced by TBHP through resuming mitochondrial function.
TN1856 Leachianone A Isokurarinone SGLT
Leachianone A (Isokurarinone) is a potential antitoxic agent, it shows inhibitory effects on cadmium- Induced cytotoxicity.
TN4618 N-trans-Sinapoyltyramine Others
N-trans-Sinapoyltyramine exhibited strong and selective cytotoxicity on the HeLa human cancer cell line with IC50 values of 9.77 ± 1.25 Μm.
T30086 Anthragallol Anthragallic acid,1,2,3-Trihydroxyanthraquinone Others
Anthragallol(1,2,3-Trihydroxyanthraquinone) displays cytotoxicity by binding to DNA.Anthragallol can be used as an analytical reagent in the production of brown pickling colors.
T5132 9-dihydro-13-acetylbaccatin III 13-Acetyl-9-dihydrobaccatin III,9-DHAB III Apoptosis
9-dihydro-13-acetylbaccatin III (9-DHAB III)is an apoptosis inducer. It shows cytotoxicity against the MCF7 cell line and drug-resistant cell line MCF7-ADR.
TMS0879 Asiaticoside B Others
Asiaticoside B is a triterpene glycoside isolated from Actaea asiatica. It has notable cytotoxicity against HepG2 and MCF-7 cancer cell lines.
T7441 Cuminaldehyde Cuminic aldehyde,Cuminal Endogenous Metabolite
Cuminaldehyde (Cuminal) is a natural aldehyde with inhibitory effect on alpha-synuclein fibrillation and cytotoxicity. Cuminaldehyde shows anticancer activity,with a pleasant smell and contributes to the aroma of essenti...
T5826 Eupalinolide A HSP
Eupalinolide B is a natural product ,and demonstrates potent cytotoxicity against A-549, BGC-823, SMMC-7721, and HL-60 tumour cell lines.
T0194 Chloroquine phosphate Chloroquine diphosphate,Aralen phosphate,Chingamin phosphate SARS-CoV , TLR , HIV Protease , Antibiotic , Parasite , Autophagy
Chloroquine phosphate (Aralen phosphate) is an aminoquinoline antimalarial and also is widely used as an autophagy inhibitor. Chloroquine also is an inhibitor of toll-like receptors (TLRs).
T3844 Deltonin ERK , Others , Akt , Endogenous Metabolite
Deltonin has an inhibition of ERK1/2 and AKT activation. Deltonin shows cytotoxicity against human HepG2 cells (IC50: 7.66 μM), mouse C26 cells (IC50: 1.22 μM), and human MDA-MB-231 cells (IC50: 1.58 μM).
T4036 Solasodine Solancarpidine,Purapuridine,Solasodin Apoptosis , Others , E1/E2/E3 Enzyme , Antifungal
Solasodine (Purapuridine)(Purapuridine) is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family. Solasodine showed selective cytotoxicity against cervical cancer cell line (HeLa) and huma...
T4S0094 Hydroxygenkwanin Luteolin 7-methylether,7-O-Methylluteolin Antioxidant
1. Hydroxygenkwanin (Luteolin 7-methylether) possesses significant the antioxidative activity . 2. Hydroxygenkwanin has cytotoxicity, may be an effective natural product to treat glioma, and the combination of Apigenin a...
T2S0357 6-Hydroxycoumarin 6-hydroxychromen-2-one Others , Carbonic Anhydrase
6-Hydroxycoumarin (6-hydroxychromen-2-one) exhibits cytotoxicity against human HL60, HCT116, COLO205 cells with activity value of 35 uM, 42 uM, 37 respectively. 6-Hydroxycoumarin is a human CA9, CA12 inhibitor.
T5746 Dictamine Dictamnine,Dectamine Apoptosis , Anti-infection , Antibacterial , Antifungal
Dictamine (Dectamine) shows anticholinesterase, anti-inflammatory, mutagenic, and has antimicrobial activity against bacteria and fungi. It has the ability to exert cytotoxicity in human cervix, colon, and oral carcinoma...
T3S0381 Chrysophanol 8-O-glucoside Serine Protease
Chrysophanol 8-O-glucoside and chrysophanol have mild cytotoxicity and anti-diabetic properties and can play metabolic roles in the insulin-stimulated glucose transport pathway
T2S1120 Ganoderenic acid B P-gp
Ganoderenic acid B, a natural product derived from Ganoderma lucidum, can work by inhibiting the transport function of ABCB1 and enhancing the cytotoxicity of chemotherapy drugs against AbCB1-mediated multidrug resistant...
TN3669 Cis-N-Feruloyltyramine Prostaglandin Receptor
Cis-N-Feruloyltyramine is a naturally occurring compound found in various plants that shows cytotoxicity against the P-388 cancer cell line. Cis-N-Feruloyltyramine is an inhibitor of in vitro prostaglandin (PG) synthesi...
TN1038 Galgravin Apoptosis
Galgravin has anti-inflammatory, and neuroprotective effects, it can promote neuronal survival and neurite outgrowth, protect hippocampal neurons against amyloid beta peptide (Abeta25-35)-induced cytotoxicity, and protec...
T3795 Corilagin Apoptosis , TLR , Reverse Transcriptase , Antibacterial , Autophagy
Corilagin has anti-inflammatory activity. Corilagin has a significant antitumour potential and lower toxicity in normal cells in vitro.Corilagin can enhance the cytotoxicity of both cisplatin and doxorubicin on the Hep3B...
TJP2872 Acevaltrate Acevaltratum,Acetoxyvaltrate ATPase , Others
1. Acevaltrate (Acevaltratum) displays high cytotoxicity against GLC(4), a human small-cell lung cancer cell line, and against COLO 320, a human colorectal cancer cell line, with IC50 values of 1-6 uM.
T3S1873 Talatisamine Potassium Channel
1. Talatisamine (12 μM) and TEA (5mM) inhibits the enhanced I(K) caused by Aβ4 oligomers, attenuates cytotoxicity of Aβ oligomers by restoring cell viability and suppressing K(+) loss related apoptotic response. 2. Talat...
TN2331 Eleutheroside B1 Influenza Virus
Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits l...
T8724 6-Methoxydihydrosanguinarine Others
6-Methoxydihydrosanguinarine is a natural product. 6-Methoxydihydrosanguinarine shows strong cytotoxicity against MCF-7 and SF-268 cell lines with IC50 values of 0.61 μM and 0.54 μM, respectively.It has antibacterial act...
TN6714 Geranylgeraniol FT-0626663,Tetraprenol,CJ24095,CJ 24095,FT0626663,CJ-24095 Apoptosis
Geranylgeraniol (FT0626663) is an isoprenoid found in fruits, vegetables, and grains, including rice. Geranylgeraniol (FT0626663) inhibits growth and induces apoptosis of various tumor cells. Geranylgeraniol (FT0626663) ...
T33492 Methyl pyropheophorbide-a MPPa (Methyl pyropheophorbide-a),NSC267052,Pyropheophorbidea,MPPa,NSC-267052,NSC 267052
Pyropheophorbide-a methyl ester (MPPa) is a PDT photosensitizer, and is also a semisynthetic natural product derived from chlorophyll a. The absorption peak of MPPa in organic solvent and in cells was at 667 and 674 nm, ...
TN1674 Garcinone D Reactive Oxygen Species , Nrf2 , STAT
Garcinone D shows significant cytotoxicity against the CEM-SS cell line, with IC(50) value of 3.2 microg/ml; it exhibits dose-dependent enzyme-based microsomal aromatase inhibitory activity. Garcinone D inhibits p65 acti...
TN1601 Effusol Caspase
Effusol is a natural product, exhibits potent scavenging activity for DPPH and ABTS radicals(IC50 values of 79 μM and 2.73 μM, respectively). Effusol rescues CA1 LTP attenuated by corticosterone, defending the hippocampa...
TN1216 2-O-Acetyl-20-hydroxyecdysone 20-Hydroxyeedysone 2-acetate Beta Amyloid , Others
2-O-Acetyl-20-hydroxyecdysone is an ecdysone present in insects and terrestrial plants. 2-O-Acetyl-20-hydroxyecdysone inhibits amyloid-β42-induced cytotoxicity and is able to reduce the formation of Aβ oligomers by promo...
T36528 Illudin M Apoptosis , DNA Alkylator/Crosslinker
Illudin M is a cytotoxic sesquiterpene from the fungus O. illudens that alkylates DNA. It has a cytotoxicity of 6-100 nM against HL-60 human leukemia cells.Illudin M has anticancer activity and is a pre-drug for the synt...
T4S0181 Hinokiflavone MMP , BCL , E1/E2/E3 Enzyme
Hinokiflavone, a novel modulator of pre-mRNA splicing activity both in vitro and in cellulo, inhibits the assembly of the spliceosome, particularly blocking the formation of the B complex. Additionally, it acts as a SUMO...
T2860 Vanillyl Alcohol 4-Hydroxy-3-methoxybenzenemethanol,3-Methoxy-4-hydroxybenzyl alcohol,4-Hydroxy-3-methoxybenzyl alcohol,Vanillin alcohol,Vanillic alcohol Apoptosis , Others
Vanillyl Alcohol (3-Methoxy-4-hydroxybenzyl alcohol) possesses anti-angiogenic, anticonvulsive, anti-inflammatory, anti-oxidant, neuroprotective, and anti-nociceptive activities. Vanillyl alcohol can effectively inhibit ...
T7028 Licochalcone C LICOCHALCONEC Phosphatase , Antioxidant , Glucosidase
Licochalcone C (LICOCHALCONEC) has potent antioxidant properties and inhibition of bacterial growth and cellular respiration. It has cardioprotection effect, via antioxidant, anti-inflammatory, and anti-apoptotic activit...
T2P2806 Hederacolchiside A1 Raddeanoside R13 Apoptosis , ERK , MEK , Akt , PI3K , Parasite , mTOR
Hederacolchiside A1 (Raddeanoside R13) shows anti-leishmanial activity, it exhibits a strong antiproliferative activity on all stages of development of the parasite by altering membrane integrity and potential. Hederacol...
T1020 Doxorubicin hydrochloride Adriamycin,Doxorubicin (Adriamycin) HCl,Hydroxydaunorubicin hydrochloride,DOX hydrochloride,NSC 123127 Apoptosis , Mitophagy , HBV , HIV Protease , Topoisomerase , Antibacterial , Antibiotic , AMPK , Autophagy
Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM). Doxorubicin hydrochloride exhibits cytotoxicity and antitum...
TWS2045 Bruceine D Apoptosis , Antiviral , Gamma-secretase , Parasite
1. Bruceine D from Brucea javanica, may have the potential to be used as a natural viricide, or a lead compound for new viricides. 2. Bruceine D inhibits the growth of three pancreatic cancer cell lines, i.e., PANC-1, SW...
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天然物製品

N-Acetyltyramine
T37341
Synonym:
Target: Antibacterial
Isoverticine
TN1807
Synonym:
Target: BCL, Caspase
Isolongifolene
T11685
Synonym: (-)-Isolongifolene
Target: Apoptosis, Others
Norwogonin
T8205
Synonym: 5,7,8-Trihydroxyflavone
Target: Virus Protease
Diphyllin
TN1103
Synonym:
Target: ATPase, Proton pump, Influenza Virus, HIV Protease
Solamargine
T4034
Synonym: Solamargin,δ-Solanigrine
Target: Apoptosis, p38 MAPK, P-gp, STAT
Uric Acid
T0626
Synonym: 2,6,8-Trioxopurine,2,6,8-Trioxypurine,2,6,8-Trihydroxypurine,Lithic acid,Urate
Target: Reactive Oxygen Species, Endogenous Metabolite, Phosphorylase
Trabectedin
T17155
Synonym: Ecteinascidin 743,ET-743
Target: Apoptosis, Reactive Oxygen Species
LANOSTEROL
T4970
Synonym: 3β-Hydroxy-8,24-lanostadiene,8,24-Lanostadien-3β-ol
Target: Endogenous Metabolite
Anhydrosafflor yellow B
TN6924
Synonym: (2S,3S)-6,7-dihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-2-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-3-{2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-oxo-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]cyclohexa-1,4-dien-1,AHSYB
Target: Others
Gambogellic acid
T11354
Synonym:
Target:
Tanshinone I
T2907
Synonym: Tanshinone A
Target: Phospholipase
Pseudoprotodioscin
T5S0246
Synonym:
Target: Others, Fatty Acid Synthase
4'-O-Methylpyridoxine
TN7032
Synonym: 4-methoxymethylpyridoxine,Ginkgotoxin
Target: Antioxidant
Cyclo(Tyr-Leu)
TN6444
Synonym:
Target: Antifungal
Vitexin-4''-O-glucoside
T3S1628
Synonym: Vitexin -4''-O-glucoside
Target: Others
Leachianone A
TN1856
Synonym: Isokurarinone
Target: SGLT
N-trans-Sinapoyltyramine
TN4618
Synonym:
Target: Others
Anthragallol
T30086
Synonym: Anthragallic acid,1,2,3-Trihydroxyanthraquinone
Target: Others
9-dihydro-13-acetylbaccatin III
T5132
Synonym: 13-Acetyl-9-dihydrobaccatin III,9-DHAB III
Target: Apoptosis
Asiaticoside B
TMS0879
Synonym:
Target: Others
Cuminaldehyde
T7441
Synonym: Cuminic aldehyde,Cuminal
Target: Endogenous Metabolite
Eupalinolide A
T5826
Synonym:
Target: HSP
Chloroquine phosphate
T0194
Synonym: Chloroquine diphosphate,Aralen phosphate,Chingamin phosphate
Target: SARS-CoV, TLR, HIV Protease, Antibiotic, Parasite, Autophagy
Deltonin
T3844
Synonym:
Target: ERK, Others, Akt, Endogenous Metabolite
Solasodine
T4036
Synonym: Solancarpidine,Purapuridine,Solasodin
Target: Apoptosis, Others, E1/E2/E3 Enzyme, Antifungal
Hydroxygenkwanin
T4S0094
Synonym: Luteolin 7-methylether,7-O-Methylluteolin
Target: Antioxidant
6-Hydroxycoumarin
T2S0357
Synonym: 6-hydroxychromen-2-one
Target: Others, Carbonic Anhydrase
Dictamine
T5746
Synonym: Dictamnine,Dectamine
Target: Apoptosis, Anti-infection, Antibacterial, Antifungal
Chrysophanol 8-O-glucoside
T3S0381
Synonym:
Target: Serine Protease
Ganoderenic acid B
T2S1120
Synonym:
Target: P-gp
Cis-N-Feruloyltyramine
TN3669
Synonym:
Target: Prostaglandin Receptor
Galgravin
TN1038
Synonym:
Target: Apoptosis
Corilagin
T3795
Synonym:
Target: Apoptosis, TLR, Reverse Transcriptase, Antibacterial, Autophagy
Acevaltrate
TJP2872
Synonym: Acevaltratum,Acetoxyvaltrate
Target: ATPase, Others
Talatisamine
T3S1873
Synonym:
Target: Potassium Channel
Eleutheroside B1
TN2331
Synonym:
Target: Influenza Virus
6-Methoxydihydrosanguinarine
T8724
Synonym:
Target: Others
Geranylgeraniol
TN6714
Synonym: FT-0626663,Tetraprenol,CJ24095,CJ 24095,FT0626663,CJ-24095
Target: Apoptosis
Methyl pyropheophorbide-a
T33492
Synonym: MPPa (Methyl pyropheophorbide-a),NSC267052,Pyropheophorbidea,MPPa,NSC-267052,NSC 267052
Target:
Garcinone D
TN1674
Synonym:
Target: Reactive Oxygen Species, Nrf2, STAT
Effusol
TN1601
Synonym:
Target: Caspase
2-O-Acetyl-20-hydroxyecdysone
TN1216
Synonym: 20-Hydroxyeedysone 2-acetate
Target: Beta Amyloid, Others
Illudin M
T36528
Synonym:
Target: Apoptosis, DNA Alkylator/Crosslinker
Hinokiflavone
T4S0181
Synonym:
Target: MMP, BCL, E1/E2/E3 Enzyme
Vanillyl Alcohol
T2860
Synonym: 4-Hydroxy-3-methoxybenzenemethanol,3-Methoxy-4-hydroxybenzyl alcohol,4-Hydroxy-3-methoxybenzyl alcohol,Vanillin alcohol,Vanillic alcohol
Target: Apoptosis, Others
Licochalcone C
T7028
Synonym: LICOCHALCONEC
Target: Phosphatase, Antioxidant, Glucosidase
Hederacolchiside A1
T2P2806
Synonym: Raddeanoside R13
Target: Apoptosis, ERK, MEK, Akt, PI3K, Parasite, mTOR
Doxorubicin hydrochloride
T1020
Synonym: Adriamycin,Doxorubicin (Adriamycin) HCl,Hydroxydaunorubicin hydrochloride,DOX hydrochloride,NSC 123127
Target: Apoptosis, Mitophagy, HBV, HIV Protease, Topoisomerase, Antibacterial, Antibiotic, AMPK, Autophagy
Bruceine D
TWS2045
Synonym:
Target: Apoptosis, Antiviral, Gamma-secretase, Parasite

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-04616 NKp30/NCR3 Protein, Cynomolgus, Rhesus, Recombinant (His) Cynomolgus,Rhesus HEK293 Cells
NKp30/NCR3 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.3 kDa and the accession number is XP_005553604.1.
TMPY-05511 NKp46/NCR1 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
NKp46/NCR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.6 kDa and the accession number is A0A0R4IZY7.
TMPY-01145 NKp30/NCR3 Protein, Human, Recombinant (His) Human HEK293 Cells
NKp30/NCR3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.4 kDa and the accession number is O14931-1.
TMPY-01807 NKp44/NCR2 Protein, Human, Recombinant (His) Human HEK293 Cells
NKp44/NCR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20 kDa and the accession number is O95944-1.
TMPY-00334 NKp30/NCR3 Protein, Rat, Recombinant (His) Rat HEK293 Cells
NKp30/NCR3 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is CAD23066.1.
TMPY-06363 B7-H6 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated Cynomolgus HEK293 Cells
B7-H6 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 29.76 kDa and the accession number is XP_005578557.1.
TMPY-04617 B7-H6 Protein, Cynomolgus, Recombinant (hFc) Cynomolgus HEK293 Cells
B7-H6 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.2 kDa and the accession number is XP_005578557.1.
TMPY-03233 NKp46/NCR1 Protein, Rat, Recombinant (hFc) Rat HEK293 Cells
NKp46/NCR1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.1 kDa and the accession number is Q9Z0H5.
TMPY-04618 B7-H6 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
B7-H6 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.9 kDa and the accession number is XP_005578557.1.
TMPY-00327 B7-H6 Protein, Rat, Recombinant (hFc) Rat HEK293 Cells
B7-H6 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 60.4 kDa and the accession number is XP_006223356.1.
TMPY-04495 B7-H6 Protein, Rat, Recombinant (His) Rat HEK293 Cells
B7-H6 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.1 kDa and the accession number is XP_006223356.1.
TMPY-00377 B7-H6 Protein, Human, Recombinant (hFc) Human HEK293 Cells
B7-H6 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.4 kDa and the accession number is Q68D85.
TMPY-04619 B7-H6 Protein, Human, Recombinant (His) Human HEK293 Cells
B7-H6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.1 kDa and the accession number is Q68D85.
TMPY-05383 NKp30/NCR3 Protein, Human, Recombinant (hFc) Human HEK293 Cells
NKp30/NCR3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.6 kDa and the accession number is O14931-3.
TMPY-06178 B7-H6 Protein, Human, Recombinant (His), Biotinylated Human HEK293 Cells
B7-H6 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.1 kDa and the accession number is Q68D85.
TMPY-05367 NKp44/NCR2 Protein, Human, Recombinant (His), Biotinylated Human HEK293 Cells
NKp44/NCR2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20 kDa and the accession number is O95944-1.
TMPJ-00083 NCR3 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Natural Cytotoxicity Triggering Receptor 3 (NCR3) along with NKp44 and NKp46 constitute a group of receptors termed “Natural Cytotoxicity Receptors”. They play a major role in triggering NK-mediated killing of most tumor...
TMPJ-00567 NCR1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Natural cytotoxicity triggering receptor 1(NCR1) is a single-pass type I membrane protein .It contains 2 Ig-like (immunoglobulin-like) domains and belongs to the natural cytotoxicity receptor (NCR) family. The protein is...
TMPY-01964 CD16a Protein, Human, Recombinant (F176V, His) Human HEK293 Cells
The Fc receptor with low affinity for IgG (FCGR3, or CD16) is encoded by 2 nearly identical genes, FCGR3A and FCGR3B, resulting in tissue-specific expression of alternative membrane-anchored isoforms. FCGR3A, it is also ...
TMPK-00091 NKp30/NCR3 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
NKp30, along with NKp44 and NKp46, constitute a group of receptors termed "Natural Cytotoxicity Receptors". These receptors play a major role in triggering NK-mediated killing of most tumor cells lines.NKp30 stimulates N...
TMPK-00090 NKp30/NCR3 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
NKp30, along with NKp44 and NKp46, constitute a group of receptors termed "Natural Cytotoxicity Receptors". These receptors play a major role in triggering NK-mediated killing of most tumor cells lines.NKp30 stimulates N...
TMPY-03623 NKp80/KLRF1 Protein, Cynomolgus, Recombinant (hFc) Cynomolgus HEK293 Cells
NKp80, also known as KLRF1, is an activating homodimeric C-type lectin-like receptor that is expressed on nearly all-natural killer cells and stimulates their cytotoxicity and cytokine release. NKp80 stimulates cytotoxic...
TMPK-00116 NKp80/KLRF1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
NKp80, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on essentially all human natural killer (NK) cells and stimulates their cytotoxicity and cytokine release.
TMPK-01468 HLA-A*02:01&B2M&MART-1 (ELAGIGILTV) Tetramer Protein, Human, MHC (His & Avi) Human HEK293 Cells
Melanoma antigen recognized by T cell-1 (Mart-1), one of the melanosome-specific proteins, also recognized by cytotoxicity T lymphocytes as a marker. Mart-1 is considered to play a critical role in the immunotherapy for ...
TMPK-00598 Fc gamma RIIIA/CD16a (V176) Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
The Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-depende...
TMPK-01469 HLA-A*02:01&B2M&MART-1 (ELAGIGILTV) Monomer Protein, Human, MHC (His & Avi) Human HEK293 Cells
Melanoma antigen recognized by T cell-1 (Mart-1), one of the melanosome-specific proteins, also recognized by cytotoxicity T lymphocytes as a marker. Mart-1 is considered to play a critical role in the immunotherapy for ...
TMPK-00136 ULBP-2 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, E...
TMPK-00260 CD155/PVR Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
CD155 is a cell surface adhesion molecule functioning in tumor cell migration, invasion, and metastasis, and not surprisingly, is also designated as a common tumor-associated antigen. CD155 is also recognized by NK cells...
TMPK-00791 Fc gamma RIIIA/CD16a (F176) Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent r...
TMPY-05055 GGH/Glutamyl hydrolase gamma Protein, Human, Recombinant (His) Human HEK293 Cells
gamma-Glutamyl hydrolase (GGH) regulates intracellular folates and antifolates such as methotrexate (MTX) for proper nucleotide biosynthesis and antifolate-induced cytotoxicity, respectively. GGH is a ubiquitously-expres...
TMPK-00599 Fc gamma RIIIA/CD16a (V176) Domain 2 Protein, Human, Recombinant (mFc) Human HEK293 Cells
Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent r...
TMPK-00597 Fc gamma RIIIA/CD16a (V176) Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent r...
TMPK-00237 2B4/CD244 Protein, Human, Recombinant (aa 22-221, His & Avi), Biotinylated Human HEK293 Cells
2B4 (CD244) is expressed by memory-phenotype CD8() T cells and all natural killer (NK) cells. The ligand for 2B4, CD48, is expressed on hematopoietic cells. 2B4 is conserved in humans and mice, and a number of reports ha...
TMPK-00747 NKp46/NCR1 Protein, Human, Recombinant (mFc) Human HEK293 Cells
NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expresse...
TMPK-00792 Fc gamma RIIIA/CD16a (F176) Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent r...
TMPK-01134 NKp46/NCR1 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expresse...
TMPY-01561 PIG3 Protein, Human, Recombinant (His) Human E. coli
Nutlin-3 variably induces apoptosis and cell cycle arrest in cancer cells while it shows low/absent cytotoxicity in normal cells, Nutlin-3 is a promising anti-cancer agent, which exhibits activity against a variety of ca...
TMPK-00746 NKp46/NCR1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expresse...
TMPK-01133 NKp46/NCR1 Protein, Cynomolgus, Recombinant (hFc) Cynomolgus HEK293 Cells
NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expresse...
TMPK-00614 NKp46/NCR1 Protein, Human, Recombinant (His) Human HEK293 Cells
NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expresse...
TMPH-03036 Cytotoxin 2 Protein, Naja atra, Recombinant (His & Myc) Naja atra E. coli
Basic protein that binds to cell membrane and depolarizes cardiomyocytes. It also shows lytic activities, but 2-fold less important than that of CTX-A4. It binds to the integrin alpha-V/beta-3 (ITGAV/ITGB3) with a modera...
TMPK-00615 NKp46/NCR1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated Human HEK293 Cells
NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expresse...
TMPH-02622 DOCK8 Protein, Mouse, Recombinant (E. coli, His) Mouse E. coli
Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP. During immune responses, required for interstitial dendritic cell (DC) migration by locally a...
TMPK-00459 Fc gamma RIIIB/CD16b (NA2) Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
Human Fc gamma RIIIB/CD16b Protein is a receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate a...
TMPK-00460 Fc gamma RIIIB/CD16b (NA2) Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
Human Fc gamma RIIIB/CD16b Protein is a receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate a...
TMPH-01207 DOCK8 Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP. During immune responses, required for interstitial dendritic cell (DC) migration by locally a...
TMPH-02623 DOCK8 Protein, Mouse, Recombinant (His) Mouse P. pastoris (Yeast)
Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP. During immune responses, required for interstitial dendritic cell (DC) migration by locally a...
TMPJ-00175 B7-H4 Protein, Rhesus macaque, Recombinant (hFc) Rhesus HEK293 Cells
B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins.It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negat...
TMPK-00971 CRTAM Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of I...
TMPK-01385 CRTAM Protein, Canine, Recombinant (His) Canine HEK293 Cells
Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of I...
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NKp30/NCR3 Protein, Cynomolgus, Rhesus, Recombinant (His)
TMPY-04616
Species: Cynomolgus,Rhesus
Expression System: HEK293 Cells
NKp46/NCR1 Protein, Mouse, Recombinant (His)
TMPY-05511
Species: Mouse
Expression System: HEK293 Cells
NKp30/NCR3 Protein, Human, Recombinant (His)
TMPY-01145
Species: Human
Expression System: HEK293 Cells
NKp44/NCR2 Protein, Human, Recombinant (His)
TMPY-01807
Species: Human
Expression System: HEK293 Cells
NKp30/NCR3 Protein, Rat, Recombinant (His)
TMPY-00334
Species: Rat
Expression System: HEK293 Cells
B7-H6 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated
TMPY-06363
Species: Cynomolgus
Expression System: HEK293 Cells
B7-H6 Protein, Cynomolgus, Recombinant (hFc)
TMPY-04617
Species: Cynomolgus
Expression System: HEK293 Cells
NKp46/NCR1 Protein, Rat, Recombinant (hFc)
TMPY-03233
Species: Rat
Expression System: HEK293 Cells
B7-H6 Protein, Cynomolgus, Recombinant (His)
TMPY-04618
Species: Cynomolgus
Expression System: HEK293 Cells
B7-H6 Protein, Rat, Recombinant (hFc)
TMPY-00327
Species: Rat
Expression System: HEK293 Cells
B7-H6 Protein, Rat, Recombinant (His)
TMPY-04495
Species: Rat
Expression System: HEK293 Cells
B7-H6 Protein, Human, Recombinant (hFc)
TMPY-00377
Species: Human
Expression System: HEK293 Cells
B7-H6 Protein, Human, Recombinant (His)
TMPY-04619
Species: Human
Expression System: HEK293 Cells
NKp30/NCR3 Protein, Human, Recombinant (hFc)
TMPY-05383
Species: Human
Expression System: HEK293 Cells
B7-H6 Protein, Human, Recombinant (His), Biotinylated
TMPY-06178
Species: Human
Expression System: HEK293 Cells
NKp44/NCR2 Protein, Human, Recombinant (His), Biotinylated
TMPY-05367
Species: Human
Expression System: HEK293 Cells
NCR3 Protein, Human, Recombinant (hFc)
TMPJ-00083
Species: Human
Expression System: HEK293 Cells
NCR1 Protein, Human, Recombinant (hFc)
TMPJ-00567
Species: Human
Expression System: HEK293 Cells
CD16a Protein, Human, Recombinant (F176V, His)
TMPY-01964
Species: Human
Expression System: HEK293 Cells
NKp30/NCR3 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00091
Species: Human
Expression System: HEK293 Cells
NKp30/NCR3 Protein, Human, Recombinant (His & Avi)
TMPK-00090
Species: Human
Expression System: HEK293 Cells
NKp80/KLRF1 Protein, Cynomolgus, Recombinant (hFc)
TMPY-03623
Species: Cynomolgus
Expression System: HEK293 Cells
NKp80/KLRF1 Protein, Human, Recombinant (hFc)
TMPK-00116
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&MART-1 (ELAGIGILTV) Tetramer Protein, Human, MHC (His & Avi)
TMPK-01468
Species: Human
Expression System: HEK293 Cells
Fc gamma RIIIA/CD16a (V176) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00598
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&MART-1 (ELAGIGILTV) Monomer Protein, Human, MHC (His & Avi)
TMPK-01469
Species: Human
Expression System: HEK293 Cells
ULBP-2 Protein, Human, Recombinant (His & Avi)
TMPK-00136
Species: Human
Expression System: HEK293 Cells
CD155/PVR Protein, Human, Recombinant (His & Avi)
TMPK-00260
Species: Human
Expression System: HEK293 Cells
Fc gamma RIIIA/CD16a (F176) Protein, Human, Recombinant (His & Avi)
TMPK-00791
Species: Human
Expression System: HEK293 Cells
GGH/Glutamyl hydrolase gamma Protein, Human, Recombinant (His)
TMPY-05055
Species: Human
Expression System: HEK293 Cells
Fc gamma RIIIA/CD16a (V176) Domain 2 Protein, Human, Recombinant (mFc)
TMPK-00599
Species: Human
Expression System: HEK293 Cells
Fc gamma RIIIA/CD16a (V176) Protein, Human, Recombinant (His & Avi)
TMPK-00597
Species: Human
Expression System: HEK293 Cells
2B4/CD244 Protein, Human, Recombinant (aa 22-221, His & Avi), Biotinylated
TMPK-00237
Species: Human
Expression System: HEK293 Cells
NKp46/NCR1 Protein, Human, Recombinant (mFc)
TMPK-00747
Species: Human
Expression System: HEK293 Cells
Fc gamma RIIIA/CD16a (F176) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00792
Species: Human
Expression System: HEK293 Cells
NKp46/NCR1 Protein, Cynomolgus, Recombinant (His)
TMPK-01134
Species: Cynomolgus
Expression System: HEK293 Cells
PIG3 Protein, Human, Recombinant (His)
TMPY-01561
Species: Human
Expression System: E. coli
NKp46/NCR1 Protein, Human, Recombinant (hFc)
TMPK-00746
Species: Human
Expression System: HEK293 Cells
NKp46/NCR1 Protein, Cynomolgus, Recombinant (hFc)
TMPK-01133
Species: Cynomolgus
Expression System: HEK293 Cells
NKp46/NCR1 Protein, Human, Recombinant (His)
TMPK-00614
Species: Human
Expression System: HEK293 Cells
Cytotoxin 2 Protein, Naja atra, Recombinant (His & Myc)
TMPH-03036
Species: Naja atra
Expression System: E. coli
NKp46/NCR1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
TMPK-00615
Species: Human
Expression System: HEK293 Cells
DOCK8 Protein, Mouse, Recombinant (E. coli, His)
TMPH-02622
Species: Mouse
Expression System: E. coli
Fc gamma RIIIB/CD16b (NA2) Protein, Human, Recombinant (His & Avi)
TMPK-00459
Species: Human
Expression System: HEK293 Cells
Fc gamma RIIIB/CD16b (NA2) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00460
Species: Human
Expression System: HEK293 Cells
DOCK8 Protein, Human, Recombinant (His)
TMPH-01207
Species: Human
Expression System: P. pastoris (Yeast)
DOCK8 Protein, Mouse, Recombinant (His)
TMPH-02623
Species: Mouse
Expression System: P. pastoris (Yeast)
B7-H4 Protein, Rhesus macaque, Recombinant (hFc)
TMPJ-00175
Species: Rhesus
Expression System: HEK293 Cells
CRTAM Protein, Mouse, Recombinant (His)
TMPK-00971
Species: Mouse
Expression System: HEK293 Cells
CRTAM Protein, Canine, Recombinant (His)
TMPK-01385
Species: Canine
Expression System: HEK293 Cells
カタログ番号 製品名
L6720 Anti-COVID-19 Traditional Chinese Medicine Compound Library

1147 compounds
A unique collection of 1147 monomers from 60 TCM plants, a powerful tool for anti-COVID-19 drug discovery, can be used for HTS and HCS screening;
L6200 The Yao nationality medicine Library

221 compounds
A collection of 221 natural product molecules originated from Yao medicine, which can be used for high-throughput and high-content screening.