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405

阻害剤

天然化合物

106

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T83892	33-BCRP Inhibitor	33-Breast Cancer Resistance Protein Inhibitor
	33-BCRP inhibitor is a compound that blocks the action of breast cancer resistance protein (BCRP), enhancing the susceptibility of mitoxantrone-resistant H460/MX20 lung cancer cells to the cytotoxic effects of mitoxantro...
TQ0186	Ko 143		BCRP , ABC
	Ko 143 is a selective inhibitor of ATP-binding cassette sub-family G member 2 (ABCG2; BCRP).		BCRP , ABC
T21876	DC_AC50		Apoptosis , Others
	DC_AC50 is a dual inhibitor of Atox1 and CCS (copper chaperones). Inhibiting intracellular copper chaperones as a means of reducing/preventing acquired chemotherapy resistance.DC_AC50 binding to Atox1 and CCS and reducin...		Apoptosis , Others
T9982	PU23		MRP
	PU 23 is an inhibitor of multidrug-resistant protein 4 (MRP4).		MRP
T3581	KS176		Potassium Channel , BCRP
	KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter, showing no inhibitory activity against P-gp or MRP1.		Potassium Channel , BCRP
T4595	YHO-13177	YHO 13177,YHO13177	BCRP
	YHO-13177 is a potent and specific inhibitor of BCRP; potentiated the cytotoxicity of SN-38 in cancer cells and no effect on P-glycoprotein–mediated paclitaxel resistance in MDR1-transduced human leukemia K562 cells.		BCRP
T13383	Zamicastat	BIA 5-1058	BCRP , Hydroxylase , P-gp
	Zamicastat (BIA 5-1058) is an inhibitor of dopamine β-hydroxylase (DBH), and is also a concentration-dependent dual inhibitor of P-gp and BCRP(IC50 values of 73.8 μM and 17.0 μM, respectively).		BCRP , Hydroxylase , P-gp
T3971	CASIN	Pirl1-related Compound 2	CDK , STAT , Ras
	CASIN (Pirl1-related Compound 2) is a specific inhibitor of GTPase Cdc42 (IC50: 2 uM).		CDK , STAT , Ras
T8157	Centhaquin	PMZ-2010,Centhaquine	Others
	Centhaquin (Centhaquine)e is an adrenergic receptor potentially for the treatment of postoperative pain and for the resuscitation of hypovolemic shock		Others
T1248	Sulfanitran		Antibacterial , Autophagy
	Sulfanitran is a sulfonamide antibiotic used in the poultry industry.		Antibacterial , Autophagy
T27617	Inz-1		P450
	Inz-1 is an effective and fungal-selective inhibitor of mitochondrial cytochrome bc1 with IC50s of 8.092 and 45.320 μM for yeast and human. Inz-1 reverses Fluconazole or other triazole antifungals’ resistance in the path...		P450
T21955	GQ-16		PPAR
	GQ-16 is a partial agonist of PPARγ with a Ki of 160 nM. GQ-16 reduces adipogenic actions and promotes insulin Sensitization without weight gain.		PPAR
T38400	Triclabendazole sulfoxide	TCBZ-SO	BCRP , Parasite
	Triclabendazole sulfoxide (TCBZ-SO) is a main plasma metabolite of Triclabendazole. Triclabendazole sulfoxide inhibits membrane transporter ABCG2/BCRP and exhibits anti-parasite effects.		BCRP , Parasite
T12832	Amcenestrant	SAR439859	Estrogen Receptor/ERR , Estrogen/progestogen Receptor
	Amcenestrant (SAR439859) is an orally active, nonsteroidal and selective degrader of estrogen receptor (SERD). SAR439859 is a potent antagonist of ER (with an EC50 of 0.2 nM for ERα degradation).		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
T4628	Seladelpar	MBX 8025	PPAR
	Seladelpar (MBX 8025) has been used in trials studying the treatment of Hyperlipidemia.		PPAR
T7656	Apelin-13
	Apelin-13 is a 13-amino acid peptide sequence found in the central and peripheral nervous system that is an endogenous ligand for the G protein-coupled receptor angiotensin II protein J (APJ), with an EC50 value of 0.37 ...
T8596	Ceefourin 1		MRP
	Ceefourin 1 is a highly selective multidrug resistance protein 4 (MRP4) inhibitor.		MRP
T2680	NVP-BVU972		c-Met/HGFR
	NVP-BVU972 is a selective and potent Met inhibitor with IC50 of 14 nM.		c-Met/HGFR
T12341	P-gp inhibitor 1		Others , P-gp
			Others , P-gp
T4337	PCI 29732	PCI29732,PCI-29732	Others , BCRP , BTK
	PCI 29732 is a selective and irreversible Btk inhibitor with IC50 of 8.2 nM in a FRET based biochemical enzymology assay.		Others , BCRP , BTK
T22459	Xanthinol Nicotinate	Angioamin,Complamin	Others
	Xanthinol Nicotinate (Complamin) is a potent vasodilator that can easily enter the cell and causes an increase in glucose metabolism resulting in an increased energy.		Others
T8426	Encequidar	HM30181,HM30181A	P-gp
	Encequidar (HM30181A) is a potent and selective P-glycoprotein inhibitor.		P-gp
T3071	Olverembatinib	GZD 824	Bcr-Abl
	Olverembatinib (GZD 824) is an orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT, IC50: 0.34 nM) and Bcr-Abl(T315I, IC50: 0.68 nM).		Bcr-Abl
T16561	Polyoxyethylene stearate	POES	Antibacterial , P-gp
	Polyoxyethylene stearate (POES) is an agent of non-ionic emulsifying.		Antibacterial , P-gp
T6287	Tariquidar	XR9576	P-gp
	Tariquidar (XR9576)(Kd=5.1 nM) is a specific and effective non-competitive inhibitor of P-glycoprotein. It can reverse drug resistance in MDR cell Lines.		P-gp
T11071	Dofequidar fumarate	MS-209	P-gp
	Dofequidar fumarate (MS-209)(MS-209 fumarate), a quinoline-based compound administered orally, is known for counteracting multidrug resistance (MDR) through the inhibition of ABCB1/P-glycoprotein (P-gp) and ABCC1/MDR-ass...		P-gp
T2620	G-749	G749	Apoptosis , FLT , c-RET , TAM Receptor , Aurora Kinase
	G-749, a new-type FLT3 inhibitor, exhibits effective and sustained inhibition of the FLT3 wild type and mutants.		Apoptosis , FLT , c-RET , TAM Receptor , Aurora Kinase
T2657	Elacridar	GW0918,GW120918,GF120918,GG918	BCRP , P-gp
	Elacridar (GG918) (GF120918) is an effective BCRP and P-gp (MDR-1) inhibitor.		BCRP , P-gp
T9179	CLP-3094	2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BE	Androgen Receptor
	CLP-3094 (2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BE) is a potent androgen receptor BF3 (binding function 3) inhibitor. BF3-IN-1 inhibits AR transcriptional activity with IC50 of 4 μM. CLP-3094 is a selective and potent GP...		Androgen Receptor
T0351	Risperidone	Risperidal,R 64 766	Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , P-gp
	Risperidone (R 64 766) is a selective blocker of dopamine D2 receptors and serotonin 5-HT2 receptors that act as an atypical antipsychotic agent.
T1275	Phentolamine mesylate	Phentolamine methanesulfonate,Phentolamine mesilate	Adrenergic Receptor
	Phentolamine mesylate (Phentolamine methanesulfonate) is a nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEAS...		Adrenergic Receptor
T7714	Temocapil		Tyrosinase
	Temocapril is an inhibitor of tyrosine kinase.		Tyrosinase
T4059	Selamectin	UK-124114	Chloride channel , P-gp , Parasite
	Selamectin (UK-124114) is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. In an H. contortus larval development assay, sel...		Chloride channel , P-gp , Parasite
T15735	Leptomycin B	CI 940,LMB	CRM1 , Antibiotic , Antifungal
	Leptomycin B (LMB) is a potent inhibitor of the nuclear export of proteins and is a potent antifungal antibiotic blocking the eukaryotic cell cycle. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a ...		CRM1 , Antibiotic , Antifungal
T13416	ZX-29		ALK
	ZX-29 is a potent and selective inhibitor of ALK(IC50 of 2.1 nM, 1.3 nM and 3.9 nM for ALK, ALK L1196M and ALK G1202R mutations, respectively), and also induces protective autophagy and has antitumor effect.		ALK
T11578L	Encequidar mesylate	HM30181 mesylate,HM30181A mesylate	P-gp
	Encequidar mesylate (HM30181A mesylate) is a competitive P-glycoprotein inhibitor.		P-gp
T2429	Olverembatinib dimesylate	GZD824 Dimesylate,HQP1351	Bcr-Abl
	Olverembatinib dimesylate (GZD824 Dimesylate) is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I).		Bcr-Abl
T8389	Trifluoperazine	trifluoroperazine	CaMK , Dopamine Receptor , Influenza Virus , Adrenergic Receptor , P-gp , Autophagy
	Trifluoperazine (trifluoroperazine) is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia.
T1967	AZD-3463	ALK/IGF1R inhibitor	Apoptosis , IGF-1R , ALK , Autophagy
	AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.		Apoptosis , IGF-1R , ALK , Autophagy
T1634	Glibenclamide	Glyburide	Potassium Channel , Mitochondrial Metabolism , CFTR , P-gp , Autophagy
	Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.
T16028	IMB-XH1	Mcl1-IN-2	BCL , Antibacterial
	IMB-XH1 (Mcl1-IN-2) is a myeloid cell factor 1 (Mcl-1) inhibitor.		BCL , Antibacterial
T0100L	Atazanavir	Zrivada,Reyataz,Latazanavir,BMS-232632	P450 , SARS-CoV , HIV Protease , P-gp
	Atazanavir (BMS-232632)(BMS-232632) is an highly effective HIV-1 protease inhibitor.		P450 , SARS-CoV , HIV Protease , P-gp
T10353	APX-115 free base	Ewha-18278 free base	NADPH-oxidase , NADPH
	APX-115 free base (Ewha-18278 free base) (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4). APX-115 effectively prevents kid...		NADPH-oxidase , NADPH
T2330	Rilpivirine	TMC278,R278474,DB08864	HIV Protease , Reverse Transcriptase
	Rilpivirine (R278474) is a diarylpyrimidine derivative and reverse transcriptase inhibitor with antiviral activity against HIV-1 that is used in the treatment of HIV infections.		HIV Protease , Reverse Transcriptase
T20656	Verapamil	NSC 135784,NSC-135784,CP-16533-1,(±)-Verapamil	P450 , Calcium Channel , P-gp
	Verapamil (CP-16533-1) is a calcium channel blocker and an orally active and effective inhibitor of P-gp. Verapamil inhibits CYP3A4 and can be used in studies about the treatment of high blood pressure, heart arrhythmias...		P450 , Calcium Channel , P-gp
T14364	AZ-Dyrk1B-33	3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine	DYRK
	AZ-Dyrk1B-33 (3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine) is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.		DYRK
T16339	Norverapamil hydrochloride	(±)-Norverapamil hydrochloride,D591 hydrochloride	Calcium Channel , P-gp , Drug Metabolite
	Norverapamil hydrochloride (D591 hydrochloride) ((±)-Norverapamil hydrochloride) is an N-demethylated metabolite of Verapamil and it is an L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor.		Calcium Channel , P-gp , Drug Metabolite
T1010	Verapamil hydrochloride	Manidon,(±)-Verapamil hydrochlorid,Verapamil HCl,Calcan hydrochloride	P450 , Calcium Channel , P-gp
	Verapamil hydrochloride (Verapamil HCl) is a calcium channel blocker that is a class IV anti-arrhythmia agent.		P450 , Calcium Channel , P-gp
T1222	Trifluoperazine dihydrochloride	Trifluoperazine 2HCl,SKF5019,Urinox	CaMK , Dopamine Receptor , Influenza Virus , Adrenergic Receptor , P-gp , Autophagy
	Trifluoperazine dihydrochloride (SKF5019) is a potent dopamine D2 receptor inhibitor used as an antipsychotic and an antiemetic.
T0100	Atazanavir sulfate	BMS-232632,BMS-232632 sulfate	P450 , SARS-CoV , HIV Protease , P-gp
	Atazanavir sulfate (BMS-232632 sulfate) is an azapeptide and HIV-PROTEASE INHIBITOR that is used in the treatment of HIV INFECTIONS and AIDS in combination with other ANTI-HIV AGENTS.		P450 , SARS-CoV , HIV Protease , P-gp

Compounds

33-BCRP Inhibitor

T83892

Synonym: 33-Breast Cancer Resistance Protein Inhibitor

Target: Apoptosis, Others

Target: Potassium Channel, BCRP

YHO-13177

T4595

Synonym: YHO 13177,YHO13177

Target: BCRP, Hydroxylase, P-gp

CASIN

T3971

Synonym: Pirl1-related Compound 2

Target: CDK, STAT, Ras

Centhaquin

T8157

Synonym: PMZ-2010,Centhaquine

Target: Antibacterial, Autophagy

Triclabendazole sulfoxide

T38400

Synonym: TCBZ-SO

Target: BCRP, Parasite

Amcenestrant

T12832

Synonym: SAR439859

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

Synonym: PCI29732,PCI-29732

Target: Others, BCRP, BTK

Xanthinol Nicotinate

T22459

Synonym: Angioamin,Complamin

Target: Others

Encequidar

T8426

Synonym: HM30181,HM30181A

Polyoxyethylene stearate

T16561

Synonym: POES

Target: Antibacterial, P-gp

Target: Apoptosis, FLT, c-RET, TAM Receptor, Aurora Kinase

Elacridar

T2657

Synonym: GW0918,GW120918,GF120918,GG918

Target: BCRP, P-gp

CLP-3094

T9179

Synonym: 2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BE

Target: Androgen Receptor

Risperidone

T0351

Synonym: Risperidal,R 64 766

Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, P-gp

Phentolamine mesylate

T1275

Synonym: Phentolamine methanesulfonate,Phentolamine mesilate

Target: Adrenergic Receptor

Target: Chloride channel, P-gp, Parasite

Leptomycin B

T15735

Synonym: CI 940,LMB

Target: CRM1, Antibiotic, Antifungal

Synonym: HM30181 mesylate,HM30181A mesylate

Target: P-gp

Olverembatinib dimesylate

T2429

Synonym: GZD824 Dimesylate,HQP1351

Target: Bcr-Abl

Trifluoperazine

T8389

Synonym: trifluoroperazine

Target: CaMK, Dopamine Receptor, Influenza Virus, Adrenergic Receptor, P-gp, Autophagy

AZD-3463

T1967

Synonym: ALK/IGF1R inhibitor

Target: Apoptosis, IGF-1R, ALK, Autophagy

Glibenclamide

T1634

Synonym: Glyburide

Target: Potassium Channel, Mitochondrial Metabolism, CFTR, P-gp, Autophagy

IMB-XH1

T16028

Synonym: Mcl1-IN-2

Target: BCL, Antibacterial

Atazanavir

T0100L

Synonym: Zrivada,Reyataz,Latazanavir,BMS-232632

Target: P450, SARS-CoV, HIV Protease, P-gp

APX-115 free base

T10353

Synonym: Ewha-18278 free base

Target: NADPH-oxidase, NADPH

Rilpivirine

T2330

Synonym: TMC278,R278474,DB08864

Target: HIV Protease, Reverse Transcriptase

Verapamil

T20656

Synonym: NSC 135784,NSC-135784,CP-16533-1,(±)-Verapamil

Target: P450, Calcium Channel, P-gp

AZ-Dyrk1B-33

T14364

Synonym: 3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine

Target: DYRK

Norverapamil hydrochloride

T16339

Synonym: (±)-Norverapamil hydrochloride,D591 hydrochloride

Target: Calcium Channel, P-gp, Drug Metabolite

Verapamil hydrochloride

T1010

Synonym: Manidon,(±)-Verapamil hydrochlorid,Verapamil HCl,Calcan hydrochloride

Target: P450, Calcium Channel, P-gp

Trifluoperazine dihydrochloride

T1222

Synonym: Trifluoperazine 2HCl,SKF5019,Urinox

Target: CaMK, Dopamine Receptor, Influenza Virus, Adrenergic Receptor, P-gp, Autophagy

Atazanavir sulfate

T0100

Synonym: BMS-232632,BMS-232632 sulfate

Target: P450, SARS-CoV, HIV Protease, P-gp

カタログ番号	製品名	別名	ターゲット
T10815	Cinnamoylglycine		Endogenous Metabolite
	Cinnamoylglycine is a glycine conjugate of cinnamic acid and a urinary metabolite in humans. It is used as a potential urinary biomarker.		Endogenous Metabolite
T3881	Vaccarin		Integrin , Akt , PERK , AMPK
	Vaccarin is a major flavonoid glycoside in Vaccariae semen, its biotransformation pathways involves methylation, hydroxylation, glycosylation and deglycosylation.		Integrin , Akt , PERK , AMPK
TN1651	Furanodiene		Apoptosis , PARP , Reactive Oxygen Species , Caspase , CDK , P-gp
	Furanodiene has anti-inflammatory and antioxidant activities, it is active against gram-positive bacteria and Candida albicans.
T3S0012	Coniferyl ferulate		P-gp , GST
	Coniferyl ferulate is a strong inhibitor of glutathione S-transferase (GST) isolated from Radix Angelicae sinensis. It shows strong inhibition of human placental GST (IC50: 0.3 μM). It also reverses multidrug resistance ...		P-gp , GST
T6670	Silymarin	Silybin B	SARS-CoV
	Silymarin (Silybin B) (Silybin B) is a polyphenolic flavonoid that extracts from the milk thistle or seeds of Silybum marianum. It is used in the prevention and treatment of liver diseases.		SARS-CoV
T2S0223	Isosinensetin	6-Demethoxynobiletin	Antioxidant , HIV Protease , Antibacterial , P-gp
	1. Isosinensetin (6-Demethoxynobiletin) shows antioxidant and HIV-1 protease inhibiting activities.		Antioxidant , HIV Protease , Antibacterial , P-gp
TN4761	Phellamurin		P-gp
	Phellamurin inhibits intestinal P-glycoprotein in a dose-dependent manner, there is a serious interaction occurred between Phellamurin with cyclosporin, to ensure the efficacy of cyclosporin, we suggest that the coadmini...		P-gp
T2869	Emodin	Frangula emodin	SARS-CoV , Casein Kinase , Autophagy
	Emodin (Frangula emodin) is a naturally occurring anthraquinone present in the roots and barks of numerous plants; exerts antiproliferative effects in Y cells that are regulated by different signaling pathways.		SARS-CoV , Casein Kinase , Autophagy
TJS1159	Chrysosplenetin	Chrysosptertin B	P450 , Ferroptosis , P-gp
	Chrysosplenetin is a metabolic inhibitor of artemisinin.		P450 , Ferroptosis , P-gp
T3002	Piperine	1-Piperoylpiperidine,Bioperine	P450 , Endogenous Metabolite , P-gp , Autophagy
	Piperine (Bioperine) , a alkaloid, has been used in trials studying the treatment of multiple myeloma and deglutition disorders.		P450 , Endogenous Metabolite , P-gp , Autophagy
T2S0271	Voacamine	Voacanginine	Cannabinoid Receptor , P-gp
	Voacamine (Voacanginine) is an indole alkaloid. Voacamine exhibits potent cannabinoid CB1 receptor antagonistic activity. Voacamine also inhibits P-glycoprotein (P-gp) action in multidrug-resistant tumor cells.Voacangini...		Cannabinoid Receptor , P-gp
TL0006	Cichoric Acid	Dicaffeoyltartaric acid,Chicoric Acid	Reactive Oxygen Species , HIV Protease
	Cichoric Acid (Dicaffeoyltartaric acid) is a potent inhibitor of human immunodeficiency virus type-1 (HIV-1) integrase and the replication in tissues. It also a class of cannabinomimetics with CB2 receptor-dependent and ...		Reactive Oxygen Species , HIV Protease
T19458	N-Hydroxypipecolic acid	1-Hydroxy-2-piperidinecarboxylic acid,NHP	Others
	N-Hydroxypipecolic acid (NHP) is a plant metabolite and a systemic acquired resistance (SAR) regulator.		Others
T2S1200	Sinapine		Antioxidant , P-gp , AChE
	1. Sinapine, an alkaloid from seeds of the cruciferous species, can be used as an effective natural compound for chemo-resistance. 2. Sinapine has antioxidant and radio-protective activities.		Antioxidant , P-gp , AChE
T4034	Solamargine	Solamargin,δ-Solanigrine	Apoptosis , p38 MAPK , P-gp , STAT
	Solamargine (δ-Solanigrine) is a major steroidal alkaloid glycoside extracted from a traditional Chinese medicine herb, Solanum nigrum L. (SNL); has been shown to inhibit growth and induce apoptosis of various cancer cel...		Apoptosis , p38 MAPK , P-gp , STAT
TN6339	(R)-5-Hydroxy-1,7-diphenylheptan-3-one	(5R)-Dihydroyashabushiketol	Others
	(R)-5-Hydroxy-1,7-diphenylheptan-3-one ((5R)-Dihydroyashabushiketol) is extracted from the rhizomes of Alpinia officinarum, a Chinese medicinal herb. (R)-5-Hydroxy-1,7-diphenylheptan-3-one inhibits melanogenesis in theop...		Others
T3392	Sinapine thiocyanate		P-gp , AChE
	Sinapine Thiocyanate, is a derivative of Sinapine (S486605), an alkaloidal amine found in black mustard seeds. It is the choline ester of Sinapic Acid (S486800). It is also a phenolic-chloine conjugates, acting as anti-o...		P-gp , AChE
T2799	(20S)-Protopanaxadiol	20-Epiprotopanaxadiol,20(S)-APPD	Apoptosis , Reactive Oxygen Species , P-gp
	(20S)-Protopanaxadiol (20-Epiprotopanaxadiol) (20-Epiprotopanaxadiol), an apoptosis inducer, is an aglycon metabolic derivative of the protopanaxadiol-type ginseng saponin.		Apoptosis , Reactive Oxygen Species , P-gp
TN1525	Convallatoxin		NF-κB , P-gp , PPAR
	Convallatoxin is a natural product		NF-κB , P-gp , PPAR
TN1757	Hypophyllanthin		Potassium Channel , Calcium Channel , P-gp
	Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice.		Potassium Channel , Calcium Channel , P-gp
TCS2336	Evodine		P-gp
	1. Evodine has antinociceptive activity.		P-gp
T19768	γ-Tocotrienol	gamma Tocotrienol,gammaTocotrienol,gamma-Tocotrienol,D-gamma-Tocotrienol,Plastochromanol	Others
	γ-Tocotrienol (Plastochromanol) is one of the four types of tocotrienol, a type of vitamin E. Itl is also a radioprotector, antioxidant. It shows antitumor and antihypertensive effects in vivo.		Others
T4085	Paris saponin VII	Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII	Apoptosis , BCL , Others , PARP , p38 MAPK , Akt , Caspase , P-gp , Autophagy
	Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.
T15355	Fumitremorgin C	12α-Fumitremorgin C	BCRP , Antibacterial , Antibiotic , ABC
			BCRP , Antibacterial , Antibiotic , ABC
TN3150	6,8-Diprenylnaringenin	Senegalensin,Lonchocarpol A	BCRP , ABC
			BCRP , ABC
T2831	Glycocholic acid	Glycocholate,cholylglycine	Others , Endogenous Metabolite
	Glycocholic acid (Glycocholate) is a bile acid with anticancer activity. Glycocholic acid targets against pump resistance-related and non-pump resistance-related pathways.		Others , Endogenous Metabolite
T3S2019	Lathyrol		Others
	1.Lathyrol diterpenes is a modulator of P-glycoprotein dependent multidrug resistance.		Others
T4461	3,5-Diiodo-L-thyronine	Diiodothyronine	Thyroid hormone receptor(THR) , Endogenous Metabolite
	3,5-Diiodo-L-thyronine (Diiodothyronine) is an iodinated thyronine hormone that regulates gene activity affecting processes such as homeostasis, lipid metabolism and insulin resistance.		Thyroid hormone receptor(THR) , Endogenous Metabolite
T3S2381	Perillene	3-Isohexenylfuran,Perillen	Others , Antibacterial
	Perillene (3-Isohexenylfuran) is an actiive constituent in the drug which promotes enterocinesia. Perillen demonstrates strong resistance activity against staphylococcus aureus and E.coli.		Others , Antibacterial
T4797	DEHP	Bis(2-ethylhexyl) phthalate	Others , Endogenous Metabolite
	DEHP (Bis(2-ethylhexyl) phthalate) is used to impart softness and flexibility to PVC products. DEHP has been implicated in obesity and insulin resistance. DEHP inhibits prostaglandin synthesis and adversely affects the e...		Others , Endogenous Metabolite
T6S1842	Tenacissoside G	Tenacissimoside A	Others
	Tenacissoside G, a C21 steroid derived from the stems of Marsdenia tenacissima, can reverse multidrug resistance in cancer cells exhibiting overexpression of P-glycoprotein.		Others
T5777	Phaseoloidin		Others
	Phaseoloidin, a homogentisic acid glucoside from Nicotiana attenuata trichomes, contributes to the plant's resistance against lepidopteran herbivores.		Others
T2A2486	3',4',5',5,7-Pentamethoxyflavone	5,7,3',4',5'-Pentamethoxyflavone	Nrf2
	3',4',5',5,7-Pentamethoxyflavone is a naturally occurring brassinosteroid compound from the Rutaceae family that exhibits resistance to cancer cells by inhibiting the Nrf2 pathway to overcome chemotherapeutically active ...		Nrf2
T4A2399	Cinobufotalin		IL Receptor , Akt , MRP , P-gp
	Cinobufotalin is a main cardiac toxin in toad, it is a novel anti-HCC agent, it induces growth inhibition and apoptosis in cultured HCC cells through ceramide production. Cinobufotalin is also an effective reversal agent...		IL Receptor , Akt , MRP , P-gp
T15091	Decoyinine	Decynylene,Angustmycin A
	Decoyinine (Decynylene), a selective inhibitor of GMP synthase, is a novel potential microbial insecticide, a secondary metabolite produced by Streptomyces hygroscopicus.Decoyinine induces resistance in rice to the small...
T0950	Neomycin sulfate	Framycin sulfate	Phospholipase , ribosome , Antibacterial , Antibiotic
	Neomycin sulfate (Framycin sulfate) is a broad-spectrum aminoglycoside antibiotic that blocks the synthesis of bacterial proteins in order to exert antimicrobial activity. Neomycin sulfate is commonly used to screen prok...		Phospholipase , ribosome , Antibacterial , Antibiotic
T4785	Oxfenicine	4-Hydroxy-L-phenylglycine	Others
	Oxfenicine (4-Hydroxy-L-phenylglycine) is a carnitine palmitoyltransferase-1 inhibitor. Oxfenicine improves whole-body glucose tolerance and insulin sensitivity in high-fat diet-induced obese mouse with insulin resistanc...		Others
T3208	Brevianamide F	Cyclo-L-tryptophyl-L-proline,cyclo-(L-Trp-L-Pro),Cyclo(L-Pro-L-Trp)	BCRP , PI3K , Antibacterial
	Brevianamide F (Cyclo(L-Pro-L-Trp)), also known as cyclo-(L-Trp-L-Pro), belongs to a class of naturally occurring 2,5-diketopiperazines. Brevianamide F possess interesting breast cancer resistance protein inhibitory acti...		BCRP , PI3K , Antibacterial
T6S0095	Genkwanin	7-O-Methylapigenin,Puddumetin,Apigenin 7-methyl ether	Virus Protease
	1. Genkwanin (Apigenin 7-methyl ether) exerts its anti-inflammatory effect mainly through the regulation of the miR-11/MKP-1/MAPK pathway. 2. Genkwanin is transported by both passive diffusion and multidrug resistance pr...		Virus Protease
TN1921	Meloside A	Isovitexin 2''-O-glucoside,Isovitexin 2''-O-β-D-glucoside	Others
	Meloside A (Isovitexin 2''-O-β-D-glucoside) is a phenylpropanoid extracted from barley. Meloside A exhibits antioxidant and protective properties against excess UV-B radiation and has been linked to resistance to pathoge...		Others
T2S0265	Robinin	NSC 9222	TLR
	Flavone glycoside from Robinia with antibacterial and diuretic properties; derived from kaempferol.The ability of robinin to reverse the multidrug resistance of the human colon cancer cell line Colo 320 expreβing MDR1/LR...		TLR
TN2256	Taccalonolide B		Microtubule Associated
	Taccalonolide B is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug-resistance protein (MRP7). Taccalonolide B inhibits growth of SK-OV-3 cells with an IC50 of 208 nM.		Microtubule Associated
T1273	Diacerein	Diacerhein,Fisiodar,Diacetylrhein	IL Receptor , Interleukin
	Diacerein (Fisiodar) is a prodrug which is metabolized to rhein. It is currently approved in France for the treatment of osteoarthritis although the use of diacerein is restricted due to the side effects including sevre ...		IL Receptor , Interleukin
T1181	Gefitinib	ZD1839	EGFR , Tyrosine Kinases , Autophagy
	Gefitinib (ZD1839) is an EGFR first-generation inhibitor with oral activity that inhibits the EGFR 19 Del and L858R mutations. Gefitinib has antitumor activity and is used for the treatment of EGFR-mutated non-small-cell...		EGFR , Tyrosine Kinases , Autophagy
T6S1885	Benzoylmesaconine	Mesaconine 14-benzoate	Others
	Benzoylmesaconine (Mesaconine 14-benzoate) is the most abundant component of Wutou decoction, which is widely used in China because of its therapeutic effect on rheumatoid arthritis. Benzoylmesconine has analgesic activi...		Others
T1022	Hygromycin B	Hygrovetine	ribosome , Antibacterial , Antibiotic , Antifungal
	Hygromycin B (Hygrovetine) is an aminoglycoside antibiotic that inhibits protein synthesis by interfering with translocation and causing mistranslation of the 70S ribosome. Hygromycin B can be used to screen prokaryotic ...		ribosome , Antibacterial , Antibiotic , Antifungal
T4S2128	Bilobetin		PKA , PPAR
	Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet.		PKA , PPAR
T5S1286	(+)-Columbianetin	(S)-Columbianetin,Columbianetin	Antifungal
	(+)-Columbianetin ((S)-Columbianetin) is a new phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage, it also has antifungal activity. (+)-Columbianetin has anti-inflammatory effect...		Antifungal
Fr13883	3-Methoxyphenylacetic acid		Others
	3-Methoxyphenylacetic acid belongs to the class of organic compounds known as anisoles. 3-Methoxyphenylacetic acid is slightly soluble (in water) and a weakly acidic compound (based on its pKa).3-Methoxyphenylacetic acid...		Others
T6S0232	Eriodictyol	Huazhongilexone	Influenza Virus , DNA/RNA Synthesis , Nrf2 , Endogenous Metabolite
	1. Eriodictyol (Huazhongilexone) is a flavonoid with anti-inflammatory and antioxidant activities. 2. Eriodictyol may possess antidiabetic properties through increasing glucose uptake and improving insulin resistance. 3....
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天然物製品

Cinnamoylglycine

T10815

Synonym:

Target: Endogenous Metabolite

Vaccarin

T3881

Synonym:

Target: Integrin, Akt, PERK, AMPK

Furanodiene

TN1651

Synonym:

Target: Apoptosis, PARP, Reactive Oxygen Species, Caspase, CDK, P-gp

Synonym: 6-Demethoxynobiletin

Target: Antioxidant, HIV Protease, Antibacterial, P-gp

Synonym: Frangula emodin

Target: SARS-CoV, Casein Kinase, Autophagy

Chrysosplenetin

TJS1159

Synonym: Chrysosptertin B

Target: P450, Ferroptosis, P-gp

Piperine

T3002

Synonym: 1-Piperoylpiperidine,Bioperine

Target: P450, Endogenous Metabolite, P-gp, Autophagy

Voacamine

T2S0271

Synonym: Voacanginine

Target: Cannabinoid Receptor, P-gp

Cichoric Acid

TL0006

Synonym: Dicaffeoyltartaric acid,Chicoric Acid

Target: Reactive Oxygen Species, HIV Protease

N-Hydroxypipecolic acid

T19458

Synonym: 1-Hydroxy-2-piperidinecarboxylic acid,NHP

Target: Antioxidant, P-gp, AChE

Solamargine

T4034

Synonym: Solamargin,δ-Solanigrine

Target: Apoptosis, p38 MAPK, P-gp, STAT

(R)-5-Hydroxy-1,7-diphenylheptan-3-one

TN6339

Synonym: (5R)-Dihydroyashabushiketol

(20S)-Protopanaxadiol

T2799

Synonym: 20-Epiprotopanaxadiol,20(S)-APPD

Target: Apoptosis, Reactive Oxygen Species, P-gp

Convallatoxin

TN1525

Synonym:

Target: NF-κB, P-gp, PPAR

Hypophyllanthin

TN1757

Synonym:

Target: Potassium Channel, Calcium Channel, P-gp

Synonym: gamma Tocotrienol,gammaTocotrienol,gamma-Tocotrienol,D-gamma-Tocotrienol,Plastochromanol

Target: Others

Paris saponin VII

T4085

Synonym: Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII

Target: Apoptosis, BCL, Others, PARP, p38 MAPK, Akt, Caspase, P-gp, Autophagy

Fumitremorgin C

T15355

Synonym: 12α-Fumitremorgin C

Target: BCRP, Antibacterial, Antibiotic, ABC

6,8-Diprenylnaringenin

TN3150

Synonym: Senegalensin,Lonchocarpol A

Target: BCRP, ABC

Glycocholic acid

T2831

Synonym: Glycocholate,cholylglycine

Target: Others, Endogenous Metabolite

3,5-Diiodo-L-thyronine

T4461

Synonym: Diiodothyronine

Target: Thyroid hormone receptor(THR), Endogenous Metabolite

Perillene

T3S2381

Synonym: 3-Isohexenylfuran,Perillen

Target: Others, Antibacterial

DEHP

T4797

Synonym: Bis(2-ethylhexyl) phthalate

Target: Others, Endogenous Metabolite

Tenacissoside G

T6S1842

Synonym: Tenacissimoside A

3',4',5',5,7-Pentamethoxyflavone

T2A2486

Synonym: 5,7,3',4',5'-Pentamethoxyflavone

Target: IL Receptor, Akt, MRP, P-gp

Decoyinine

T15091

Synonym: Decynylene,Angustmycin A

Target:

Neomycin sulfate

T0950

Synonym: Framycin sulfate

Target: Phospholipase, ribosome, Antibacterial, Antibiotic

Oxfenicine

T4785

Synonym: 4-Hydroxy-L-phenylglycine

Target: Others

Brevianamide F

T3208

Synonym: Cyclo-L-tryptophyl-L-proline,cyclo-(L-Trp-L-Pro),Cyclo(L-Pro-L-Trp)

Target: BCRP, PI3K, Antibacterial

Genkwanin

T6S0095

Synonym: 7-O-Methylapigenin,Puddumetin,Apigenin 7-methyl ether

Target: Virus Protease

Meloside A

TN1921

Synonym: Isovitexin 2''-O-glucoside,Isovitexin 2''-O-β-D-glucoside

Target: Microtubule Associated

Diacerein

T1273

Synonym: Diacerhein,Fisiodar,Diacetylrhein

Target: IL Receptor, Interleukin

Gefitinib

T1181

Synonym: ZD1839

Target: EGFR, Tyrosine Kinases, Autophagy

Benzoylmesaconine

T6S1885

Synonym: Mesaconine 14-benzoate

Target: ribosome, Antibacterial, Antibiotic, Antifungal

Synonym: (S)-Columbianetin,Columbianetin

Target: Antifungal

3-Methoxyphenylacetic acid

Synonym: Huazhongilexone

Target: Influenza Virus, DNA/RNA Synthesis, Nrf2, Endogenous Metabolite

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-00871	BAR Protein, S. hygroscopicus, Recombinant	Streptomyces hygroscopicus	E. coli
	Phosphinothricin N-acetyltransferase (PAT) is an enzyme that acetylates the free NH2 group of L-phosphinothricin (L-PPT) in the presence of acetyl-CoA as a co-substrate. It is highly specific for L-PPT and does not acety...
TMPH-00981	ABCB1 Protein, Human, Recombinant (His)	Human	E. coli
	ABCB1 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-01711	ABCC1 Protein, Human, Recombinant (His)	Human	E. coli
	ABCC1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 35.9 kDa and the accession number is P33527.
TMPY-04069	Neurotrophin 3 Protein, Human, Recombinant	Human	E. coli
	NTF3 (Neurotrophin 3) is a Protein Coding gene. The protein encoded by this gene is a member of the neurotrophin family, that controls the survival and differentiation of mammalian neurons. This protein is closely relate...
TMPY-01009	TGFBI Protein, Human, Recombinant (His)	Human	HEK293 Cells
	TGFBI is an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several ...
TMPY-00566	CCL18 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	CCL18 is a chemotactic cytokine involved in the pathogenesis and progression of various disorders, including cancer. Proof showed high levels of CCL18 in the serum of epithelial ovarian carcinoma patients suggesting its...
TMPH-02373	Metallo-beta-lactamase type 2 Protein, Klebsiella pneumoniae, Recombinant (His)	Klebsiella pneumoniae	E. coli
	Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring. Does not confer resistance to the polymixin colistin or the fluoroquinol...
TMPH-00753	UspD Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Required for resistance to DNA-damaging agents.
TMPH-00585	Beta-lactamase CTX-M-1 Protein, E. coli, Recombinant (Yeast, His)	E. coli	P. pastoris (Yeast)
	Broad spectrum beta-lactamase which confers resistance to penicillins, as well as first, second and third-generation cephalosporins.
TMPH-03717	YopE Protein, Yersinia enterocolitica, Recombinant (His)	Yersinia enterocolitica	E. coli
	Essential virulence determinant; cytotoxic effector, involved in resistance to phagocytosis.
TMPH-00738	TetR5 Protein, E. coli, Recombinant (His)	E. coli	E. coli
	TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline re...
TMPH-00584	Beta-lactamase CTX-M-1 Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Broad spectrum beta-lactamase which confers resistance to penicillins, as well as first, second and third-generation cephalosporins.
TMPH-00774	SAM22 Protein, Glycine max, Recombinant (His)	Glycine max	P. pastoris (Yeast)
	Involved in disease resistance. SAM22 Protein, Glycine max, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 18.8 kDa and the accession number is P26987.
TMPH-03473	UspA Protein, Salmonella typhi, Recombinant (His)	Salmonella typhi	E. coli
	Required for resistance to DNA-damaging agents. UspA Protein, Salmonella typhi, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 19.9 kDa and the accession n...
TMPH-00737	TetR2 Protein, E. coli, Recombinant (His & SUMO)	E. coli	E. coli
	TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline re...
TMPH-03360	PTMA Protein, Rat, Recombinant (His)	Rat	P. pastoris (Yeast)
	Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections. PTMA Protein, Rat, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 1...
TMPH-00587	Beta-lactamase TEM Protein, E. coli, Recombinant (His & SUMO)	E. coli	E. coli
	TEM-type are the most prevalent beta-lactamases in enterobacteria; they hydrolyze the beta-lactam bond in susceptible beta-lactam antibiotics, thus conferring resistance to penicillins and cephalosporins. TEM-3 and TEM-4...
TMPH-02371	SHV-5 Protein, Klebsiella pneumoniae, Recombinant (His & Myc)	Klebsiella pneumoniae	E. coli
	SHV enzymes hydrolyze broad spectrum cephalosporins notably cefotaxime and ceftazidime. SHV-5 causes particularly high levels of resistance to aztreonam and ceftazidime.
TMPH-03519	ACP Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	P. pastoris (Yeast)
	Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. ACP Protein, S. aureus, Recombinant (His) is expressed in yeast with N-6xHi...
TMPH-00586	Beta-lactamase TEM Protein, E. coli, Recombinant (His)	E. coli	P. pastoris (Yeast)
	TEM-type are the most prevalent beta-lactamases in enterobacteria; they hydrolyze the beta-lactam bond in susceptible beta-lactam antibiotics, thus conferring resistance to penicillins and cephalosporins. TEM-3 and TEM-4...
TMPY-03049	GALNT10 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Ectopic expression and knockdown studies showed that GALNT10 indeed promotes proliferation and apoptosis resistance of hepatoma cells in a glycosyltransferase-dependent manner. The genetic variants on LEKR1 and GALNT10 g...
TMPH-02379	ArnT Protein, Klebsiella pneumoniae, Recombinant (His)	Klebsiella pneumoniae	E. coli
	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antim...
TMPH-00035	Polyphenol oxidase 2 Protein, Agaricus bisporus, Recombinant (His)	Agaricus bisporus	Baculovirus Insect Cells
	Copper-containing oxidase that catalyzes both the o-hydroxylation of monophenols and the subsequent oxidation of the resulting o-diphenols into reactive o-quinones, which evolve spontaneously to produce intermediates, wh...
TMPH-01847	Parathymosin Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Parathymosin may mediate immune function by blocking the effect of prothymosin alpha which confers resistance to certain opportunistic infections. Parathymosin Protein, Human, Recombinant (His & Myc) is expressed in E. c...
TMPJ-00710	ALDH1A2 Protein, Human, Recombinant (His)	Human	E. coli
	Aldehyde dehydrogenase 1 family member A2 (ALDH1A2), also known as retinaldehyde dehydrogenase 2 (RALDH2), belongs to the aldehyde dehydrogenase family which contains two members, the ALDH1 s (ALDH1A1, ALDH1A2 and ALDH1A...
TMPH-03608	Phosphinothricin N-acetyltransferase Protein, S. viridochromogenes, Recombinant (His)	Streptomyces viridochromogenes	P. pastoris (Yeast)
	Inactivates phosphinothricin (PPT) by transfer of an acetyl group from acetyl CoA. This enzyme is an effector of phosphinothricin tripeptide (PTT or bialaphos) resistance. Phosphinothricin N-acetyltransferase Protein, S....
TMPH-03518	ACP Protein, S. aureus, Recombinant (GST)	Staphylococcus aureus	E. coli
	Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. ACP Protein, S. aureus, Recombinant (GST) is expressed in E. coli expressio...
TMPH-03053	Hydrophobin Protein, Neosartorya fumigata, Recombinant (B2M & His)	Neosartorya fumigata	E. coli
	Cell wall protein regularly arranged in interwoven fascicules of clustered proteinaceous microfibrils, or rodlets, to form the outer spore coat protein. It is involved in resistance to environmental stress and may well b...
TMPH-03609	Phosphinothricin N-acetyltransferase Protein, S. viridochromogenes, Recombinant (His & SUMO)	Streptomyces viridochromogenes	E. coli
	Inactivates phosphinothricin (PPT) by transfer of an acetyl group from acetyl CoA. This enzyme is an effector of phosphinothricin tripeptide (PTT or bialaphos) resistance. Phosphinothricin N-acetyltransferase Protein, S....
TMPH-02153	Sulfiredoxin-1 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduct...
TMPH-03520	ACP Protein, S. aureus, Recombinant (His & SUMO)	Staphylococcus aureus	E. coli
	Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. ACP Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli ex...
TMPH-00714	SapA Protein, E. coli, Recombinant (His & Myc)	E. coli	E. coli
	Not part of a putrescine export system. Very similar to a S.typhimurium protein implicated in antimicrobial peptide resistance, but the SapBCDF operon in E.coli is implicated in putrescine export. SapA Protein, E. coli, ...
TMPH-03604	Phosphinothricin N-acetyltransferase Protein, Streptomyces hygroscopicus, Recombinant (His)	Streptomyces hygroscopicus	E. coli
	Inactivates phosphinothricin (PPT) by transfer of an acetyl group from acetyl CoA. Can also acetylate demethylphosphinothricin but not PTT or glutamate. This enzyme is an effector of phosphinothricin tripeptide (PTT or b...
TMPY-02660	Resistin Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Resistin is an adipocytokine, which has been studied for its role in insulin resistance and recently in inflammation. The RETN and CAP1 polymorphisms and gene expression may be potential biomarkers for breast cancer risk...
TMPH-02463	HMf-2 Protein, Methanothermus fervidus, Recombinant (His)	Methanothermus fervidus	E. coli
	Binds and compacts DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils. Increases the resistance of DNA to thermal denaturation in vitro. HMf-2 Protein, Methanothermus fervi...
TMPH-02462	HMf-1 Protein, Methanothermus fervidus, Recombinant (His & Myc)	Methanothermus fervidus	E. coli
	Binds and compacts DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils. Increases the resistance of DNA to thermal denaturation. HMf-1 Protein, Methanothermus fervidus, Reco...
TMPH-03488	Metallo-beta-lactamase type 2 Protein, Serratia marcescens, Recombinant (His & Myc)	Serratia marcescens	E. coli
	Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring. Metallo-beta-lactamase type 2 Protein, Serratia marcescens, Recombinant ...
TMPH-00079	Beta-amylase 3, chloroplastic Protein, Arabidopsis thaliana, Recombinant (His)	Arabidopsis thaliana	E. coli
	Beta-amylase activity. No alpha-amylase activity. Involved in cold resistance. Mediates the accumulation of maltose upon freezing stress, thus contributing to the protection of the photosynthetic electron transport chain...
TMPH-00169	PBP 3 Protein, Bacillus subtilis, Recombinant (His)	Bacillus subtilis	E. coli
	Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis. Probably required for both cortical and vegetative peptidoglycan synthesis. Although not usually required for cell division, in the ab...
TMPK-00516	BST1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	BST1 overexpression conferred resistance to sphingosine in yeast. BST1 deletion produced sensitivity to exogenous D-erythro-sphingosine and phytosphingosine and intracellular accumulation of sphingosine 1-phosphate upon ...
TMPJ-00932	PBLD Protein, Human, Recombinant (His)	Human	E. coli
	Phenazine Biosynthesis-Like Domain-Containing protein (PBLD) belongs to the phenazine biosynthesis-like protein (PhzF) family, which is expressed in most tissues. PBLD takes part in the MAPK signaling pathway, and is inv...
TMPY-00481	AKR1C4 Protein, Human, Recombinant (His)	Human	E. coli
	Aldo-keto reductases comprise of AKR1C1-AKR1C4, four enzymes that catalyze NADPH dependent reductions and have been implicated in biosynthesis, intermediary metabolism, and detoxification. there is a strong correlation ...
TMPK-00060	IL-17B Protein, Mouse, Recombinant (His)	Mouse	E. coli
	IL-17A, the prototypic member of the IL-17 family, several experimental findings strongly support the role of the IL-17B/IL-17 receptor B (IL-17RB) pathway in tumorigenesis and resistance to anticancer therapies. IL-17B/...
TMPH-01431	HELQ Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Single-stranded DNA-dependent ATPase and 5' to 3' DNA helicase. Involved in the repair of DNA cross-links and double-strand break (DSB) resistance. Participates in FANCD2-mediated repair. Forms a complex with POLN polyme...
TMPH-03561	LsdB Protein, S. aureus, Recombinant (His & SUMO)	Staphylococcus aureus	E. coli
	Cell wall-anchored surface receptor that extracts heme from oxidized metHb to enable growth on hemoglobin as a sole iron source. Rapidly extracts heme from hemoglobin and transfers it to IsdA or IsdC, which then relays i...
TMPH-02866	RBBP9 Protein, Mouse, Recombinant (His)	Mouse	P. pastoris (Yeast)
	Serine hydrolase whose substrates have not been identified yet. May negatively regulate basal or autocrine TGF-beta signaling by suppressing SMAD2-SMAD3 phosphorylation. May play a role in the transformation process due ...
TMPJ-00726	NEO Protein, K. pneumoniae, Recombinant	Klebsiella pneumoniae	E. coli
	Aminoglycoside 3'-phosphotransferase (APH(3')), also known as aminoglycoside kinase, is an aminoglycoside-modifying enzyme and widely presented in resistant bacteria. These ATP-dependent enzymes phosphorylate the 3'-hydr...
TMPK-00875	CD96 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	The receptors CD96 and TIGIT are expressed on the surface of T and natural killer (NK) cells, and recent studies suggest both play important inhibitory roles in immune function. CD96 has been shown to modulate immune cel...
TMPY-00607	PSMB6 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	PSMB6 subunit belongs to the 20S proteasomal subunit family, which plays an importance role in the antigen presentation by MHC class I molecular. Proteasome subunit beta type 6 (PSMB6) is a member of 20S proteasomal subu...
TMPK-00408	AXL Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpre...
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BAR Protein, S. hygroscopicus, Recombinant

TMPJ-00871

Species: Streptomyces hygroscopicus

Expression System: E. coli

ABCB1 Protein, Human, Recombinant (His)

TMPH-00981

Species: Human

Expression System: E. coli

ABCC1 Protein, Human, Recombinant (His)

TMPH-01711

Species: Human

Expression System: E. coli

Neurotrophin 3 Protein, Human, Recombinant

TMPY-04069

Species: Human

Expression System: E. coli

TGFBI Protein, Human, Recombinant (His)

TMPY-01009

Species: Human

Expression System: HEK293 Cells

CCL18 Protein, Human, Recombinant (His)

TMPY-00566

Species: Human

Expression System: P. pastoris (Yeast)

Metallo-beta-lactamase type 2 Protein, Klebsiella pneumoniae, Recombinant (His)

TMPH-02373

Species: Klebsiella pneumoniae

Expression System: E. coli

UspD Protein, E. coli, Recombinant (His)

TMPH-00753

Species: E. coli

Expression System: E. coli

Beta-lactamase CTX-M-1 Protein, E. coli, Recombinant (Yeast, His)

TMPH-00585

Species: E. coli

Expression System: P. pastoris (Yeast)

YopE Protein, Yersinia enterocolitica, Recombinant (His)

TMPH-03717

Species: Yersinia enterocolitica

Expression System: E. coli

TetR5 Protein, E. coli, Recombinant (His)

TMPH-00738

Species: E. coli

Expression System: E. coli

Beta-lactamase CTX-M-1 Protein, E. coli, Recombinant (His)

TMPH-00584

Species: E. coli

Expression System: E. coli

SAM22 Protein, Glycine max, Recombinant (His)

TMPH-00774

Species: Glycine max

Expression System: P. pastoris (Yeast)

UspA Protein, Salmonella typhi, Recombinant (His)

TMPH-03473

Species: Salmonella typhi

Expression System: E. coli

TetR2 Protein, E. coli, Recombinant (His & SUMO)

TMPH-00737

Species: E. coli

Expression System: E. coli

PTMA Protein, Rat, Recombinant (His)

TMPH-03360

Species: Rat

Expression System: P. pastoris (Yeast)

Beta-lactamase TEM Protein, E. coli, Recombinant (His & SUMO)

TMPH-00587

Species: E. coli

Expression System: E. coli

SHV-5 Protein, Klebsiella pneumoniae, Recombinant (His & Myc)

TMPH-02371

Species: Klebsiella pneumoniae

Expression System: E. coli

ACP Protein, S. aureus, Recombinant (His)

TMPH-03519

Species: Staphylococcus aureus

Expression System: P. pastoris (Yeast)

Beta-lactamase TEM Protein, E. coli, Recombinant (His)

TMPH-00586

Species: E. coli

Expression System: P. pastoris (Yeast)

GALNT10 Protein, Human, Recombinant (His)

TMPY-03049

Species: Human

Expression System: HEK293 Cells

arnT Protein, Klebsiella pneumoniae, Recombinant (His)

TMPH-02379

Species: Klebsiella pneumoniae

Expression System: E. coli

Polyphenol oxidase 2 Protein, Agaricus bisporus, Recombinant (His)

TMPH-00035

Species: Agaricus bisporus

Expression System: Baculovirus Insect Cells

Parathymosin Protein, Human, Recombinant (His & Myc)

TMPH-01847

Species: Human

Expression System: E. coli

ALDH1A2 Protein, Human, Recombinant (His)

TMPJ-00710

Species: Human

Expression System: E. coli

Phosphinothricin N-acetyltransferase Protein, S. viridochromogenes, Recombinant (His)

TMPH-03608

Species: Streptomyces viridochromogenes

Expression System: P. pastoris (Yeast)

ACP Protein, S. aureus, Recombinant (GST)

TMPH-03518

Species: Staphylococcus aureus

Expression System: E. coli

Hydrophobin Protein, Neosartorya fumigata, Recombinant (B2M & His)

TMPH-03053

Species: Neosartorya fumigata

Expression System: E. coli

Phosphinothricin N-acetyltransferase Protein, S. viridochromogenes, Recombinant (His & SUMO)

TMPH-03609

Species: Streptomyces viridochromogenes

Expression System: E. coli

Sulfiredoxin-1 Protein, Human, Recombinant (His & Myc)

TMPH-02153

Species: Human

Expression System: E. coli

ACP Protein, S. aureus, Recombinant (His & SUMO)

TMPH-03520

Species: Staphylococcus aureus

Expression System: E. coli

SapA Protein, E. coli, Recombinant (His & Myc)

TMPH-00714

Species: E. coli

Expression System: E. coli

Phosphinothricin N-acetyltransferase Protein, Streptomyces hygroscopicus, Recombinant (His)

TMPH-03604

Species: Streptomyces hygroscopicus

Expression System: E. coli

Resistin Protein, Mouse, Recombinant (hFc)

TMPY-02660

Species: Mouse

Expression System: HEK293 Cells

HMf-2 Protein, Methanothermus fervidus, Recombinant (His)

TMPH-02463

Species: Methanothermus fervidus

Expression System: E. coli

HMf-1 Protein, Methanothermus fervidus, Recombinant (His & Myc)

TMPH-02462

Species: Methanothermus fervidus

Expression System: E. coli

Metallo-beta-lactamase type 2 Protein, Serratia marcescens, Recombinant (His & Myc)

TMPH-03488

Species: Serratia marcescens

Expression System: E. coli

Beta-amylase 3, chloroplastic Protein, Arabidopsis thaliana, Recombinant (His)

TMPH-00079

Species: Arabidopsis thaliana

Expression System: E. coli

PBP 3 Protein, Bacillus subtilis, Recombinant (His)

TMPH-00169

Species: Bacillus subtilis

Expression System: E. coli

BST1 Protein, Cynomolgus, Recombinant (His)

TMPK-00516

Species: Cynomolgus

Expression System: HEK293 Cells

PBLD Protein, Human, Recombinant (His)

TMPJ-00932

Species: Human

Expression System: E. coli

AKR1C4 Protein, Human, Recombinant (His)

TMPY-00481

Species: Human

Expression System: E. coli

IL-17B Protein, Mouse, Recombinant (His)

TMPK-00060

Species: Mouse

Expression System: E. coli

HELQ Protein, Human, Recombinant (His & Myc)

TMPH-01431

Species: Human

Expression System: E. coli

lsdB Protein, S. aureus, Recombinant (His & SUMO)

TMPH-03561

Species: Staphylococcus aureus

Expression System: E. coli

RBBP9 Protein, Mouse, Recombinant (His)

TMPH-02866

Species: Mouse

Expression System: P. pastoris (Yeast)

NEO Protein, K. pneumoniae, Recombinant

TMPJ-00726

Species: Klebsiella pneumoniae

Expression System: E. coli

CD96 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00875

Species: Human

Expression System: HEK293 Cells

PSMB6 Protein, Mouse, Recombinant (His)

TMPY-00607

Species: Mouse

Expression System: E. coli

AXL Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00408

Species: Human

Expression System: HEK293 Cells

--------- More ---------

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