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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T16834 | S26131 | N-[2-[7-[3-[8-(2-acetamidoethyl)naphthalen-2-yl]oxypropoxy]naphthalen-1-yl]ethyl]acetamide | MT Receptor |
S26131 (N-[2-[7-[3-[8-(2-acetamidoethyl)naphthalen-2-yl]oxypropoxy]naphthalen-1-yl]ethyl]acetamide) behaves as an antagonist on MT1 and MT2 receptors with Ki of 0.5 and 112 nM respectively. | |||
T32108 | HXJ42 | HXJ-42,HXJ 42 | Others |
HXJ42 is a PP1 analog that selectively and effectively acts on wild-type ZAP-70 (AS). | |||
T17266 | Xipamide | Diurexan,Aquaphor | Others |
Xipamide (Diurexan) is a sulfonamide-based diuretic with antihypertensive properties. Xipamide selectively inhibits anion exchanger. | |||
T8361 | Tetraethylammonium bromide | TEAB,TEA bromide | Potassium Channel |
Tetraethylammonium bromide (TEA bromide) can selectively block potassium channels. | |||
T77628 | Bisindolylmaleimide III | PKC | |
Bisindolylmaleimide III is a potent and selective inhibitor of protein kinase C (PKC).Bisindolylmaleimide III selectively interacts with PKCα or ribosomal S6 protein kinase 1 upon activation of these kinases. | |||
T8819 | SU-9516 | CDK | |
SU9516 is a selectively potent ATP-competitive inhibitor of CDKs. | |||
T9604 | Beta-Estradiol 17-hemisuccinate | Estrogen Receptor/ERR | |
beta-Estradiol 17-hemisuccinate selectively stains estrogen receptor (ER)-rich cells. | |||
T7830 | Windorphen | Wnt/beta-catenin | |
Windorphen is a Wnt inhibitor that selectively abrogates the Wnt signaling. | |||
T5536 | SJA710-6 | Others | |
SJA710-6 is able to selectively differentiate MSCs toward hepatocyte-like cells. | |||
T11533 | Z-HA155 | CS-963 | PDE |
Z-HA155 (CS-963) selectively and potently inhibits autotaxin with an IC50 of 5.7 nM. | |||
T19319 | Ethyl docosa-4,7,10,13,16,19-hexaenoate | Others | |
Ethyl cis-4,7,10,13,16,19-Docosahexaenoate, the ethyl ester of Docosahexaenoate (DHA), is selectively enriched in the ethyl ester fraction through the alcoholysis process involving fatty acid ethyl esters from tuna oil a... | |||
T6418 | BMS-378806 | BMS378806,BMS-806 | gp120/CD4 , HIV Protease |
BMS-378806 (BMS-806) selectively inhibits the binding of HIV-1 gp120 to the CD4 receptor with EC50 of 0.85-26.5 nM in virus. | |||
T7008 | Vacquinol-1 | Vacquinol 1 | JNK |
Vacquinol-1 is an MKK4 activator, which rapidly and selectively induces glioma cell death. | |||
T37562 | C16 Ceramide | N-acylsphingosine,C16 Ceramide (d18:1/16:0),Palmitoyl Ceramide,N-Palmitoylsphingosine | p53 |
C16 Ceramide (Palmitoyl Ceramide) is a naturally occurring small molecule that activates p53 by directly and selectively binding to it. | |||
T15769 | LMT-28 | IL Receptor | |
LMT-28 is an inhibitor of IL-6 and selectively inhibits IL-6-induced phosphorylation of gp130, STAT3, and JAK2. | |||
T24542 | NP-313 | NP 313,NSC 4264,NSC-4264,NSC4264 | |
NP-313 (NSC-4264) is a potent antithrombotic agent that inhibits platelet aggregation and activation by inhibiting thromboxane A 2 synthesis and selectively inhibiting SOCC-mediated Ca2+ efflux. | |||
T6801 | CeMMEC13 | Carboxypeptidase , DNA/RNA Synthesis | |
CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF1 (IC50 = 2.1 μM). | |||
T8745 | PROTAC BRAF-V600E degrader-1 | Compound 23 | Raf |
PROTAC BRAF-V600E degrader-1 (Compound 23) selectively induces degradation of BRAF-V600E but not wildtype BRAF. | |||
T28895 | T-0509 | T 0509,T0509 | Adrenergic Receptor |
T-0509 is a selective beta 1 receptor agonist that increases inotropy in canine ventricular muscle and selectively down-regulates rat cardiac beta 1-adrenoceptors. | |||
TP1015 | NFAT Inhibitor | VIVIT peptide | Others |
NFAT Inhibitor (VIVIT peptide) is a cell-permeable compound that selectively inhibits calcineurin-mediated dephosphorylation of NFAT. | |||
T11153 | EG00229 | Others | |
EG00229 is a neuropilin 1 (NRP1) receptor antagonist that selectively inhibits the binding of VEGF-A to the NRP1 b1 domain, achieving this inhibition with an IC50 value of 3 μM. It does not affect the binding of VEGF-A t... | |||
T37596 | Terevalefim | c-Met/HGFR | |
Terevalefim (ANG-3777) is an hepatocyte growth factor (HGF) mimetic. Terevalefim selectively activates the c-Met receptor. | |||
T5170 | KHS101 hydrochloride | FGFR , Microtubule Associated | |
KHS101 is a TACC3 inhibitor and can selectively induce a neuronal differentiation phenotype. | |||
T7175 | Alflutinib mesylate | AST2818 mesylate | EGFR |
Alflutinib mesylate (AST2818 mesylate) ,is an irreversible tyrosine kinase inhibitor that selectively inhibits EGFR mutations, especially T790M. | |||
T11234 | ESI-08 | cAMP | |
ESI-08 is an effective antagonist of EPAC2 with an IC50 of 8.4 μM. ESI-08 selectively blocks cAMP-induced EPAC activation but not cAMP-mediated PKA activation. | |||
T6388 | Amprenavir | 141W94,Prozei,KVX-478,VX-478 | SARS-CoV , HIV Protease |
Amprenavir (KVX-478) is a synthetic derivative of hydroxyethylamine sulfonamide that selectively binds to and inhibits human immunodeficiency virus (HIV) protease. | |||
T0333 | Aniracetam | Ro 13-5057 | Dopamine Receptor , 5-HT Receptor , GluR , AChR , iGluR |
Aniracetam (Ro 13-5057)(Ro 13-5057), a nootropic and neuroprotective drug, selectively modulates the AMPA receptor and nAChR. | |||
T9587 | CCTA-1523 | Others , ABC | |
CCTA-1523 is an efflux function of ABCG2 inhibitor. CCTA-1523 selectively reverses ABCG2-mediated MDR in cancer cells. | |||
T1801 | SR9243 | Liver X Receptor | |
SR9243, an LXR inverse agonist, can induce LXR-corepressor interaction; shows anticancer activity and selectively targets the lipogenesis and Warburg effect. | |||
T6180 | INH6 | Apoptosis , Microtubule Associated | |
INH6, an effective Hec1 inhibitor, selectively disrupts the Hec1/Nek2 interaction and induces chromosome mis-alignment. | |||
T8234 | ML401 | EBI2/GPR183 | |
ML401 is a selectively EBI2(GPR183) receptor antagonist(IC50 of 1.03 nM) . | |||
T28773 | SI-2 | SI2,EPH 116,EPH116,EPH-116 | Others |
SI-2 is an inhibitor (SMI) of steroid receptor coactivator-3 (SRC-3 or AIB1). SI-2 can selectively reduce the transcriptional activities and the protein concentrations of SRC-3 in cells, and selectively induce breast can... | |||
T11142 | EACC | Autophagy | |
EACC, a reversible autophagy inhibitor, selectively impedes Stx17, an autophagosome-specific SNARE, from translocating, hence obstructing the fusion between autophagosomes and lysosomes. This compound effectively halts a... | |||
T5097 | Ezatiostat | TER199(free base),TLK199 | Apoptosis , Glutathione Peroxidase , GST |
Ezatiostat (TER199(free base)) is a tripeptide analog of glutathione that can selectively inhibit GSTP1-1 catalytic activity. | |||
T5345 | V-9302 | Others | |
V-9302 (V9302) is a competitive antagonist of transmembrane glutamine flux that selectively and potently targets the amino acid transporter ASCT2 (IC50: 9.6 uM). | |||
T10459 | Banoxantrone dihydrochloride | AQ4N dihydrochloride,AZD1689 2HCl | NOS |
T19518L | Physalaemin acetate | Neurokinin receptor | |
Physalaemin acetate is a non-mammalian tachykinin with high affinity when binding selectively to neurokinin-1 (NK1) receptor. | |||
T2037 | TH588 | DNA/RNA Synthesis , MTH1 | |
TH588 is nudix hydrolase family inhibitor that effectively and selectively engages and inhibits the MTH1(IC50: 5 nM) in cells. | |||
T9575 | MRTX9768 | Histone Methyltransferase | |
MRTX-9768 is a synthetic lethal-based inhibitor designed to bind the PRMT5-MTA complex and selectively target MTAP/CDKN2A-deleted tumors. | |||
T24159 | IHR-1 | IHR 1 | Smo |
IHR-1 is a Potent Smo antagonist (IC50 = 7.6 nM). Selectively inhibits Hedgehog signaling over Wnt and Notch signaling pathways. Blocks Smo accumulation in primary cilium in vitro. | |||
T15019 | CUR61414 | Hedgehog/Smoothened | |
CUR61414 is a cell-permeable inhibitor of Hedgehog signaling pathway (IC50 =100-200 nM) and selectively binds to smoothened (Ki = 44 nM). | |||
T0101 | Doxazosin mesylate | UK 33274 mesylate | Mitophagy , Adrenergic Receptor , Autophagy |
Doxazosin mesylate (UK 33274 mesylate)(UK 33274) is a quinazoline-derivative. It is a selectively antagonizes postsynaptic α1-adrenergic receptors. | |||
T10276 | AKT Kinase Inhibitor | Akt | |
T4348 | Syk Inhibitor II | 5-HT Receptor , Syk | |
Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM). | |||
T2298 | ML204 | TRP/TRPV Channel | |
ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels. | |||
T21674L | PKA inhibitor fragment (6-22) amide Acetate | PKA inhibitor fragment (6-22) amide Acetate(121932-06-7 Free base) | PKA |
PKA inhibitor fragment (6-22) amide Acetate is a synthetic peptide which selectively inhibits PKA activity by binding to its substrate site (IC50 < 2 nM). | |||
T5313 | Sobetirome | IACS-010759,QRX-431 | Thyroid hormone receptor(THR) |
Sobetirome (IACS-010759) is a selective agonist of thyroid hormone receptor β (TRβ) and binds selectively to TRβ-1 (EC50: 0.16 μM). | |||
T1519 | Rimonabant hydrochloride | SR 151716A,SR 141716A | Cannabinoid Receptor , Antibacterial |
Rimonabant hydrochloride (SR 141716A) is a cannabinoid receptor antagonist, binding selectively to central cannabinoid receptors (CB1) with high affinity. | |||
T3082 | SGC0946 | Histone Methyltransferase | |
SGC0946 is a highly effective and specific DOT1L methyltransferase inhibitor (IC50: 0.3 nM); selectively kill mixed lineage leukemia cells. | |||
T8874 | FB23 | Others | |
FB23 directly binds to FTO and selectively inhibits FTO's m6A demethylase activity. (FTO, an mRNA N6-methyladenosine (m6A) demethylase, was reported to promote leukemogenesis.) |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T0344L | Miconazole nitrate | NSC 169434 Nitrate,R18134 nitrate | Antibacterial , Antibiotic , Antifungal |
Miconazole nitrate (R18134 nitrate), an imidazole antifungal agent, selectively affects the integrity of fungal cell membranes, high in ergosterol content and different in composition from mammalian cells membranes. | |||
T8165 | Erythrodiol | Endogenous Metabolite , ABC | |
Erythrodiol, an olive oil component, promotes Cholesterol efflux (ChE) by selectively inhibiting the degradation of ABCA1 protein. | |||
T3719 | Daminozide | Succinic Acid,DMASA,Aminozide | Histone Demethylase |
Daminozide (Succinic Acid) is a plant growth regulator, selectively inhibits the KDM2/7 JmjC subfamily. | |||
TN3575 | (±)-Cannabichromene | Cannabichromene,Cannabichrome | Cannabinoid Receptor |
(±)-Cannabichromene is a major non-psychotropic phytocannabinoid that inhibits endocannabinoid inactivation and activates the transient receptor potential ankyrin-1 (TRPA1), it selectively reduces inflammation-induced hy... | |||
T1879 | 3-Methyladenine | 3-MA,NSC 66389 | Mitophagy , PI3K , Endogenous Metabolite , Autophagy |
3-Methyladenine (3-MA) is a PI3K inhibitor that selectively inhibits class IB PI3Kγ (IC50=60 μM) and class III VPS34 (IC50=25 μM). 3-Methyladenine inhibits autophagy. | |||
T6290 | Tanespimycin | 17-AAG,CP 127374,NSC 330507,KOS 953 | Apoptosis , Mitophagy , HSP , Antibacterial , Antibiotic , Autophagy |
Tanespimycin (KOS 953) (17-AAG) is an inhibitor of Hsp90 that selectively inhibits BT474 tumor cell Hsp90 (IC50: 5 nM). | |||
TJS1183 | Cyclen | 1,4,7,10-tetraazacyclododecane | Others |
Cyclen (1,4,7,10-tetraazacyclododecane) is a macrocycle capable of selectively binding cations that used as a ligand in chemistry for instance with chemicals used in MRI contrast agents. | |||
T1521 | (±)-10-Hydroxycamptothecin | Hydroxy Camptothecine,10-Hydroxycamptothecin | Topoisomerase |
(±)-10-Hydroxycamptothecin (Hydroxy Camptothecine) is an alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA topoisomerase, type I. S... | |||
TN1560 | Dehydroeffusol | 5-Ethenyl-1-Methylphenanthrene-2,7-Diol,Dehydro Effusol | MMP , ERK , GPR , Others |
Dehydroeffusol (Dehydro Effusol) possesses anti-cancer, anxiolytic and sedative properties. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reti... | |||
TN6848 | Piperonylic acid | 2H-1,3-benzodioxole-5-carboxylic acid | P450 |
Piperonylic acid (2H-1,3-benzodioxole-5-carboxylic acid) is a natural molecule bearing a methylenedioxy function that closely mimics the structure of trans-cinnamic acid. Piperonylic acid selectively inactivate the CYP73... | |||
T2996 | Tetrandrine | NSC-77037,d-Tetrandrine,Hanfangchin A,Fanchinine,Sinomenine A | Potassium Channel , Calcium Channel |
Tetrandrine (Sinomenine A) is a natural, bis-benzylisoquinoline alkaloid isolated from the root of the plant. Tetrandrine non-selectively inhibits calcium channel activity and induces G1 blockade of the G1 phase of the c... | |||
T8641 | Vancomycin | Antibacterial , Antibiotic , Autophagy | |
Vancomycin is a glycopeptide antibiotic that exerts its antimicrobial activity by altering the permeability of cell membranes and selectively inhibiting ribonucleic acid synthesis. Vancomycin can be used for the treatmen... | |||
T6947 | Piperlongumine | PPLGM,Piplartine | Apoptosis , ERK , Ferroptosis , Reactive Oxygen Species , ROS , Antibacterial , Autophagy |
Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L. It selectively kills cancer cells and strengthens the level of reactive oxygen species (ROS). | |||
T3030 | L-Sophoridine | Sophoridine,Matridin-15-one | Others |
L-Sophoridine (Matridin-15-one) , a natural product obtained from medicinal plants, which has a variety of pharmacological effects, including anti-Y effects, and selectively induces apoptotic cell death in a variety of h... | |||
T3862 | Irigenin | NF-κB , Integrin | |
Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra Domain A domain. It can sensitize TRAIL-induced apoptosis by enha... | |||
TN1037 | Groenlandicine | Topoisomerase | |
Groenlandicine is a protoberberine alkaloid from Coptidis Rhizoma. Groenlandicine exhibits moderate inhibitory effect with IC50 value of 154.2 μM for human recombinant aldose reductase (HRAR). Groenlandicine selectively ... | |||
T4900 | (±)-Methyl Jasmonate | (±)-Jasmonic Acid methyl ester,Methyl 2-(3-oxo-2-(pent-2-en-1-yl)cyclopentyl)acetate | Others , Endogenous Metabolite |
Methyl 2-(3-oxo-2-(pent-2-en-1-yl)cyclopentyl)acetate ((±)-Jasmonic Acid methyl ester)induces the synthesis of proteinase inhibitors in plant leaves. In cancer cells, it suppresses proliferation and induces apoptosis. Mo... | |||
T13752 | L-(+)-Arabinose | Endogenous Metabolite | |
L-(+)-Arabinose selectively inhibits intestinal sucrase activity in a non-competitive manner, inhibiting glucose elevation caused by sucrose intake. | |||
TQ0163 | Sagittatoside A | Icariin-A | Estrogen/progestogen Receptor |
Sagittatoside A selectively activates estrogen response element (ERE)-luciferase activity via ERα. | |||
T11274 | Ferulenol | Others | |
T35605 | Apoptolidin | ||
Apoptolidin is an apoptosis inducer originally isolated from Nocardiopsis bacteria. It inhibits the mitochondrial F1FO ATPase (Ki = 4-5 μM). Apoptolidin selectively kills transformed glial cells without significantly aff... | |||
T78477 | Drupanin | ||
Drupanin, isolated from green propolis, selectively inhibits the AKR1C3 enzyme and shows promise for breast cancer research [1]. | |||
T62625 | 11-O-Methylpseurotin A | ||
11-O-Methylpseurotin A, a mixed polyketide synthase-non-ribosomal peptide synthase (PKS/NRPS) compound, selectively inhibited Hof1-deficient strains. | |||
T78491 | Phytohemagglutinin P | PHA-P | |
Phytohemagglutinin P (PHA-P) is a mitogen that selectively stimulates hematogenous or lymphoid monocytic cells [1]. | |||
TN2681 | Elasticamide | 2-(2'-Hydroxytetracosanoylamino)-octadecane-1,3,4-triol | Others |
(2S,3S,4R,2'R)-2-(2'-hydroxytetracosanoylamino)octadecane-1,3,4-triol shows selectively inhibitory activity against phospholipase A 2 (PLA 2) secreted from Crotalus adamenteus venom at concentration of 100 ug/mL. | |||
T27564 | Hymenidin | 5-HT Receptor | |
Hymenidin, an alkaloid isolated from the Okinawan sponge Hymeniacidon sp. is a 5-hydroxytryptaminergic receptor antagonist and voltage-gated potassium channel inhibitor with potential antiprotozoal effects.It selectively... | |||
TN2682 | 2-2'-(Hydroxytetracosanoylamino)-octadecane-1,3,4-triol tetraacetate | Others | |
(2S,3S,4R,2'R )-2-(2'-Hydroxytetracosanoylamino) octadecane-1,3,4-triol at concentration of 100 ug/mL shows selectively inhibitory activity against phospholipase A 2 (PLA 2) secreted from Crotalus adamenteus venom, but i... | |||
TN2147 | Retrorsine | P450 , OCT | |
Retrorsine selectively inhibits hepatocyte proliferation and following liver injury evokes small hepatocyte-like progenitor cells. Retrorsine can be used for the research of hepatocellular injury. | |||
T19886 | Cirsilineol | Fastigenin,SPM 927,Eupatrin | Apoptosis , COX , STAT |
Cirsilineol (Eupatrin) is isolated from the herb of Artemisia vestita Wall and shows immunosuppressive, anti-proliferative, and anti-tumor properties. Cirsilineol selectively induces apoptosis via the mitochondrial pathw... | |||
TN3655 | Cimiside E | ERK , TNF , ROS , Akt , PI3K , PKC , PPAR | |
Cimiside E has anti-inflammatory activity, it selectively inhibits TNF-α-induced expression of VCAM-1 at least by upregulation of PPAR-γ, and signals for ERK1/2, PI3K, and PKC are involved in this effect.Cimiside E may b... | |||
T37055 | Cytostatin | ||
Cytostatin is a natural antitumor inhibitor of cell adhesion to extracellular matrix, blocking adhesion of B16 melanoma cells to laminin and collagen type IV in vitro (IC50s = 1.3 and 1.4 μg/ml, respectively) and B16 cel... | |||
T75630 | Ganoderic acid Mf | ||
Ganoderic acid Mf, an antitumor triterpenoid, selectively induces apoptosis in cancer cells through a mitochondria-mediated pathway while demonstrating high selectivity between normal and cancer cells. It also arrests th... | |||
T75686 | Enfumafungin | ||
Enfumafungin, a triterpene glycoside extracted from Hormonema carpetanum fungus, acts as an antifungal by inhibiting (1,3)-beta-D-glucan synthase, crucial for fungal cell wall synthesis. It selectively targets yeasts and... | |||
T69254 | Ajmalicine hydrochloride | Raubasine hydrochloride | |
Ajmalicine (Raubasine) hydrochloride, a potent adrenolytic compound, selectively inhibits α1-adrenoceptors and acts as a reversible, non-competitive full inhibitor of nicotine receptors with an IC50 of 72.3 μM. This chem... | |||
TN5033 | Skullcapflavone I | IL Receptor , Caspase , Prostaglandin Receptor | |
Skullcapflavone I has anti-inflammatory and anti-allergic potential, it can significantly inhibit LPS stimulated NO and PGE(2) release in J774A.1 macrophages and inhibit LPS induced IL-6 production in a concentration dep... | |||
T36417 | Nargenicin | Antibiotic 47444 | |
Nargenicin is a macrolide antibiotic that selectively inhibits the growth of S. aureus, methicilin resistant S. aureus (MRSA), and M. luteus (MICs = 0.6, 0.3, and 2.5 μg/ml, respectively) over a panel of 11 Gram-positive... | |||
T37609 | (rel)-Asperparaline A | ||
Aspergillimide is a fungal metabolite originally isolated from A. japonicus.1 It reduces nicotinic acetylcholine receptor (nAChR) peak and slowly-desensitizing amplitudes induced by acetylcholine in silkworm (B. mori) la... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-00570 | Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyro... | |||
TMPY-04552 | AKT1 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
v-akt murine thymoma viral oncogene homolog 1 (AKT1), or protein kinase B-alpha (PKB-ALPHA) is a serine-threonine protein kinase, belonging to the Protein Kinase Superfamily. AKT1 is a major mediator of the responses to ... | |||
TMPY-01460 | ABHD4 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Abhydrolase domain containing 4 (ABHD4), also known as alpha/beta-hydrolase 4 (ABH4) , or lyso-N-acylphosphatidylethanolamine lipase, which belongs to the ABHD4/ABHD5 subfamily of peptidase S33 family. Abhydrolase domain... | |||
TMPH-01563 | IAPP Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. | |||
TMPK-01332 | LY6G6D Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
LY6G6D is a selectively expressed colorectal cancer antigen that can be used for targeting a therapeutic T-cell response by a T-cell engager.LY6G6D was identified as a selectively expressed CRC antigen that can be utiliz... | |||
TMPK-00753 | LY6G6D Protein, Human, Recombinant (His) | Human | HEK293 Cells |
LY6G6D is a selectively expressed colorectal cancer antigen that can be used for targeting a therapeutic T-cell response by a T-cell engager.LY6G6D was identified as a selectively expressed CRC antigen that can be utiliz... | |||
TMPH-02635 | EEF1AKMT2 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'. EEF1AKMT2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted... | |||
TMPK-00754 | LY6G6D Protein, Human, Recombinant (His & Strep-II) | Human | HEK293 Cells |
LY6G6D is a selectively expressed colorectal cancer antigen that can be used for targeting a therapeutic T-cell response by a T-cell engager.LY6G6D was identified as a selectively expressed CRC antigen that can be utiliz... | |||
TMPK-00752 | LY6G6D Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
LY6G6D is a selectively expressed colorectal cancer antigen that can be used for targeting a therapeutic T-cell response by a T-cell engager.LY6G6D was identified as a selectively expressed CRC antigen that can be utiliz... | |||
TMPH-01811 | OR7D4 Protein, Human, Recombinant (His & KSI) | Human | E. coli |
Odorant receptor. Selectively activated by androstenone and the related odorous steroid androstadienone. OR7D4 Protein, Human, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The p... | |||
TMPH-01562 | IAPP Protein, Human, Recombinant (GST) | Human | E. coli |
Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. IAPP Protein, Human, Recombinant (GST) is expressed in E. coli expression s... | |||
TMPH-01779 | RNASE2 Protein, Human, Recombinant (His) | Human | E. coli |
This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological... | |||
TMPH-00304 | SV2A Protein, Bovine, Recombinant (His & Myc) | Bovine | HEK293 Cells |
Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of s... | |||
TMPK-01482 | HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ... | |||
TMPK-01519 | HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ... | |||
TMPK-01515 | HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ... | |||
TMPK-01483 | HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated | Human | HEK293 Cells |
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ... | |||
TMPK-00708 | TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induces apoptosis selectively via its interaction with the death receptors TRAILR1/DR4 and TRAILR2/DR5 in a wide range of cancers, while sparing norma... | |||
TMPK-01478 | HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein, Human, MHC (His & Avi), Biotinylated | Human | HEK293 Cells |
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ... | |||
TMPK-01477 | HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated | Human | HEK293 Cells |
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ... | |||
TMPK-01417 | HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled | Human | HEK293 Cells |
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ... | |||
TMPK-01436 | HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled | Human | HEK293 Cells |
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ... | |||
TMPK-01520 | HLA-A*02:01&B2M&AFP (PLFQVPEPV) Tetramer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ... | |||
TMPK-01521 | HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ... | |||
TMPK-01484 | HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ... | |||
TMPK-00070 | BAFFR/TNFRSF13C Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
BAFF binds to three TNF receptor superfamily members: B-cell maturation antigen (BCMA/TNFRSF17), transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI/TNFRSF13B) and BAFF receptor (BAFF R/... | |||
TMPK-00163 | IL-33 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Interleukin-33 (IL-33) is a cytokine belonging to the IL-1 family, playing a role in inflammatory, infectious and autoimmune diseases and expressed in the cellular nucleus in several tissues. High levels of IL-33 are exp... | |||
TMPH-02285 | USP6 Protein, Human, Recombinant (His & KSI) | Human | E. coli |
Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activit... | |||
TMPK-01254 | BAFFR/TNFRSF13C Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
BAFF binds to three TNF receptor superfamily members: B-cell maturation antigen (BCMA / TNFRSF17), transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI/TNFRSF13B) and BAFF receptor (BAFF ... | |||
TMPJ-00946 | TALDO1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Transaldolase (TALDO1) belongs to the transaldolase family of Type 1 subfamily. TALDO1 is expressed selectively in oligodendrocytes of the brain. TALDO1 is a key enzyme of the nonoxidative pentose phosphate pathway provi... | |||
TMPK-00249 | TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
TNF-related apoptosis inducing ligand (TRAIL) is a potential antitumor protein known for its ability to selectively eliminate various types of tumor cells without exerting toxic effects in normal cells and tissues. TRAIL... | |||
TMPK-01534 | Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human&Mouse, MHC (His & Avi) | Human & Mouse | HEK293 Cells |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel... | |||
TMPK-01530 | HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human, MHC (His & Avi), Biotinylated | Human | HEK293 Cells |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel... | |||
TMPK-01498 | HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Tetramer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel... | |||
TMPK-01535 | Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human&Mouse, MHC (His & Avi) | Human & Mouse | HEK293 Cells |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel... | |||
TMPJ-00708 | CST7 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Mouse Cystatin F belongs to cystatin superfamily, which encompasses proteins that contain multiple cystatin-like sequences. It has been shown that Cystatin F is selectively expressed by hematopoietic cells and may be a b... | |||
TMPK-01144 | Kremen-1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
KREMEN1 (KRM1) has been identified as a functional receptor for Coxsackievirus A10 (CV-A10), a causative agent of hand-foot-and-mouth disease (HFMD), which poses a great threat to infants globally. KRM1 selectively binds... | |||
TMPK-00248 | TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
TNF-related apoptosis inducing ligand (TRAIL) is a potential antitumor protein known for its ability to selectively eliminate various types of tumor cells without exerting toxic effects in normal cells and tissues. TRAIL... | |||
TMPK-01533 | HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel... | |||
TMPK-01502 | HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Monomer Protein, Human, MHC (His & Avi), Biotinylated | Human | HEK293 Cells |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel... | |||
TMPK-01542 | HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel... | |||
TMPK-01503 | HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Monomer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel... | |||
TMPH-02020 | RGS17 Protein, Human, Recombinant (GST) | Human | E. coli |
Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2. Inhibits signal transduction by increasing the GTPase activity of G pro... | |||
TMPH-01036 | Caprin-1/CAPRIN1 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs... | |||
TMPJ-00134 | Pro-BDNF Protein, Human, Recombinant | Human | E. coli |
The precursor form of Brain-Derived Neurotrophic Factor (pro-BDNF) interacts preferentially with the pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin and induces neuronal apoptosis, w... | |||
TMPJ-01001 | CCL11 Protein, Human, Recombinant | Human | E. coli |
C-C Motif Chemokine 11 (CCL11) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. In response to the presence of allergens, CCL11 selectively recruits eosinophils, a prominent feature of all... | |||
TMPJ-00272 | RELT/TNFRSF19L Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Tumor necrosis factor receptor superfamily member 19L (TNFRSF19L), also known as Receptor expressed in lymphoid tissues and RELT, is a member of the TNF-receptor superfamily. TNFRSF19L is a single-pass type membrane prot... | |||
TMPJ-00650 | FIBP Protein, Human, Recombinant | Human | E. coli |
Acidic Fibroblast Growth Factor Intracellular-Binding Protein (FIBP) is highly expressed in the heart, skeletal muscle, and pancreas. Acidic Fibroblast Growth Factor is a member of the fibroblast growth factor (FGF) fam... | |||
TMPH-01235 | APOBEC3A Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus... | |||
TMPJ-00128 | SLAMF2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
CD48 is a GPI-linked protein in the CD2 family of immunoglobulin superfamily proteins. CD48 is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic prog... | |||
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カタログ番号 | 製品名 | ||
---|---|---|---|
L3800 | NF-κB Signaling Compound Library | 729 compounds | |
A unique collection of 729 compounds targeting NF-κB signaling for high throughput screening and high content screening; | |||
L2010 | Highly Selective Inhibitor Library | 575 compounds | |