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226

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天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T6703	Tetrahydrozoline hydrochloride	Murine Plus,Tetryzoline hydrochloride,Tyzine,Tetrahydrozoline HCl	Adrenergic Receptor
	Tetrahydrozoline hydrochloride (Murine Plus) is an imidazoline derivative with alpha receptor agonist activity.		Adrenergic Receptor
T79921	Moloney murine leukemia virus RT		DNA/RNA Synthesis
	Moloney murine leukemia virus reverse transcriptase (MMLV RT) is a monomeric replicative polymerase intrinsic to the retrovirus life cycle [1].		DNA/RNA Synthesis
T38155	N-Acetyl-D-cysteine		Reactive Oxygen Species
	N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group.		Reactive Oxygen Species
T0120	Voriconazole	UK-109496	Antifection , Antifungal
	Voriconazole (UK-109496) is a triazole antifungal agent that specifically inhibits STEROL 14-ALPHA-DEMETHYLASE and CYTOCHROME P-450 CYP3A.		Antifection , Antifungal
T1209	Flunixin meglumine	Banamine,Finadyne,Flunixin meglumin	COX
	Flunixin meglumine (Banamine) is an effective inhibitor of the enzyme cyclooxygenase with anti-inflammatory and antipyretic activity.		COX
T12575	Unesbulin	PTC596	Apoptosis , BMI-1
	Unesbulin (PTC596) is an orally active and selective inhibitor of B-cell-specific Moloney murine leukemia virus integration site 1 (BMI-1).		Apoptosis , BMI-1
T19794	Temafloxacin	Omniflox	Antibiotic
	Temafloxacin (Omniflox) is an antibiotic and antimycobacterial agent. It used to treat lower respiratory tract infections, genital and urinary infections like prostatitis, and skin infections.		Antibiotic
T12684	Radioprotectin-1	5-chloro-2-[4-(1,3-dioxobenzo[de]isoquinolin-2-yl)butylsulfamoyl]benzoic acid	LPA Receptor
			LPA Receptor
T22893	L-168049	L-168,049	Glucagon Receptor
	L-168049 is a selective and non-competitive antagonist of human glucagon receptor with IC50s of 3.7 nM, 63 nM, and 60 nM for human, murine, and canine, respectively.		Glucagon Receptor
T17103	TM-N1324		Others , GHSR
	TM-N1324 is a GPR39 agonist. TM-N1324 activates human GPR39 with high efficacy and potencies of 280 nM and 9 nM in the absence and presence of Zn2+, respectively. TM-N1324 has similar potencies to murine GPR39 with EC50s...		Others , GHSR
T14924	Cenerimod	ACT-334441	S1P Receptor
	Cenerimod (ACT-334441) is an orally active, selective, and potent sphingosine 1-phosphate receptor (S1P1) agonist (EC50: 1 nM).Cenerimod inhibits multiple S1P isoforms and can be used to study murine experimental autoimm...		S1P Receptor
T38514	PMEDAP		Others , HIV Protease
	PMEDAP is a potent inhibitor of Moloney murine sarcoma virus (MSV)-induced tumor formation and associated mortality and an inhibitor of human immunodeficiency virus (HIV) replication. PMEDAP also has anti-murine cytomega...		Others , HIV Protease
T40380	17α-Hydroxyprogesterone acetate		Others
	17α-Hydroxyprogesterone acetate possesses progestational activity. 17α-Hydroxyprogesterone acetate shows antiinflammatory effects at the murine maternal-fetal interface.		Others
T1792L	Regorafenib monohydrate		Raf , VEGFR , c-RET , PDGFR , c-Kit , Autophagy
	Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine VEGFR3, PDGFR-β, KIT, RET, RAF-1, B-RAF and B-RAF(V600E) respect...		Raf , VEGFR , c-RET , PDGFR , c-Kit , Autophagy
T78337	Mouse IgG2a kappa, Isotype Control
	Mouse IgG2a kappa, Isotype Control is an isotype antibody to murine-derived IIgG2a kappa antibody.
T7506	Yoda 1		Piezo Channel
	Yoda1 is a Piezo1 ion channel agonist (EC50s = 17.1 and 26.6 μM for murine and human Piezo1-transfected HEK293T cells, respectively)		Piezo Channel
T10133	3'-Azido-3'-deoxy-5-methylcytidine		Antiviral , HIV Protease
	3'-Azido-3'-deoxy-5-methylcytidine inhibits HIV-1 reverse transcriptase(EC50 = 0.06 μM) and is an effective inhibitor of xenotropic murine leukemia-related retrovirus (XMRV, CC50 = 43.5 μM).		Antiviral , HIV Protease
TQ0156	GW1929		PPAR
	GW1929 is a potent PPAR-γ agonist (pKi: 8.84 for human PPAR-γ; pEC50s of 8.56 and 8.27 for human and murine PPAR-γ).		PPAR
T3589	NSC23005 Sodium		CDK
	NSC23005 sodium is a novel and effective p18 inhibitor (ED50=5.21 nM) in promoting Hematopoietic stem cells (HSCs) expansion in both murine and human models.		CDK
T24706	RBC10	RBC 10,RBC-10	GTPase
	RBC10 inhibits the binding of Ral to its effector RALBP1, as well as inhibiting Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-independent growth of human cancer cell lines.		GTPase
T9588	JI130		Others
	JI130 is able to impair the ability of Hes1 to repress transcription. JI130 treatment significantly reduced tumor volume in a murine pancreatic tumor xenograft model.		Others
T7183	CPI-444	V81444,ciforadenant	Adenosine Receptor
	CPI-444 (V81444) is an antagonist of the adenosine A2A receptor.It reduces tumor area in mouse model of murine Her2/neu-expressing breast cancer.		Adenosine Receptor
T17018	TCPOBOP		BCL
	TCPOBOP is a constitutive androstane receptor agonist that induces robust hepatocyte proliferation and hepatomegaly. TCPOBOP decreases Fas-induced murine liver injury by altering Bcl-2 proteins.		BCL
T10397	ATN-161 trifluoroacetate salt	ATN-161 TFA salt	Integrin
	ATN-161 trifluoroacetate salt (ATN-161 TFA salt) is a novel integrin α5β1 antagonist that inhibits angiogenesis and growth of liver metastases and improves survival in a murine model.		Integrin
T3502	C29		TLR
	C29 is a novel inhibitor of TLR2/1 and TLR2/6 signaling induced by synthetic and bacterial TLR2 agonists in human HEK-TLR2 and THP-1 cells, but only TLR2/1 signaling in murine macrophages.		TLR
TP1600L	Iα52 acetate(137756-45-7 free base)		Others
	Iα52 acetate is a naturally processed peptide encompassed the residues 52-68 of the murine I-Eα chain and may contribute to selection of immature T cells.		Others
T9411	KX2-361		Others , Microtubule Associated , Src
	KX2-361 is a orally bioavailable small molecule dual Src/tubulin inhibitor that provides long term survival in a murine model of glioblastoma		Others , Microtubule Associated , Src
T67936	BAY-0069		PPAR
	BAY-0069 is a potent and selective PPARγ transactivator that inhibits human PPARγ and murine PPARγ with IC50s of 6.3 nM and 24 nM, respectively.BAY-0069 can be used in cancer research.		PPAR
T5341	WYC-209	WYC209	Apoptosis , Retinoid Receptor , Autophagy
	WYC-209 inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs, IC50: 0.19 uM). It targets the retinoic acid receptor (RAR).		Apoptosis , Retinoid Receptor , Autophagy
T21578	NSC 66811		Mdm2
	NSC 66811is a novel inhibitor of the murine double minute 2 (MDM2)-p53 interaction. It binds to MDM2 with a Ki of 120 nM and activates p53 in cancer cells with a mechanism of action consistent with targeting the MDM2-p53...		Mdm2
T3080	Pyridone 6	Janus-Associated Kinase Inhibitor I,JAK Inhibitor,CMP 6,JAK Inhibitor I	Tyrosine Kinases , JAK
	Pyridone 6 (JAK Inhibitor)(CMP 6) is a potent and selective inhibitor of JAK1 (IC50=15 nM, murine JAK1), JAK2 (IC50=1 nM), JAK3 (Ki=5 nM), and Tyk2 (IC50=1 nM); displaying significantly weaker affinities (130 nM to 10 mM...		Tyrosine Kinases , JAK
T8223	Avacopan	CCX168	Complement System
	Avacopan (CCX168) is an orally administered small-molecule C5aR ( IC50 : 0.1 nM.)antagonist that blocks the effects of C5a and prevents the development of GN induced by anti-myeloperoxidase antibodies in a murine model o...		Complement System
T77408	Abagovomab	ACA 125	Others
	Abagovomab (Anti-Human CA-125 Recombinant Antibody) is a murine monoclonal antibody that targets the tumor-associated antigen CA-125. Abagovomab is produced by hybridoma cells in mice. Abagovomab can be used to study ova...		Others
T78268	Anti-Mouse NK1.1 Antibody (PK136)
	Anti-Mouse NK1.1 Antibody (PK136) is an IgG2a class antibody of murine origin targeting NK1.1, which eliminates NK1.1 and NK1.1NKT cells and inhibits NK1.1 signaling in peripheral blood, spleen, and lung tissues, and can...
T11090L1	Aldoxorubicin hydrochloride	Aldoxorubicin hydrochloride (1361644-26-9 Free base）	Topoisomerase
	Aldoxorubicin hydrochloride is an albumin-binding prodrug of Doxorubicin, a DNA topoisomerase II inhibitor. Aldoxorubicin hydrochloride is released from albumin under acidic conditions. Aldoxorubicin hydrochloride exhibi...		Topoisomerase
T6273	Vadimezan	DMXAA,5,6-Dimethylxanthenone-4-acetic Acid,NSC 640488,ASA-404	Influenza Virus , VDA , STING , IFNAR
	Vadimezan (DMXAA) is a vascular disrupting agent, a murine STING agonist, and an inducer of cytokines such as type I IFN. Vadimezan has antitumor activity and induces a rapid cessation of blood flow in tumors without aff...		Influenza Virus , VDA , STING , IFNAR
T8695	5-Hydroxymethyldeoxyuridine		Others
	5-Hydroxymethyldeoxyuridine is an analog of nucleoside that has anticancer and antiviral activities. It suppresses the replication of murine S180 lung carcinoma cells and Ehrlich ascites mammary carcinoma cells (ED50s = ...		Others
T6695	Tasquinimod	ABR-215050	HDAC
	Tasquinimod (ABR-215050) is a quinoline-3-carboxamide linomide analog with antiangiogenic and potential antineoplastic activities. Tasquinimod has been shown to decrease blood vessel density but the exact mechanism of ac...		HDAC
T60440	Antiviral agent 17
	Antiviral agent 17 (Compound 4) is an anti-infection agent that retains its strong antiviral effect in a human replicon assay with an EC50 of 0.015 μM. Antiviral agent 17 shows good antiviral activity against murine noro...
T3486	3-MATIDA		GluR , NMDAR
	3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a). Displays ≥ 40-fold selectivity over other receptors: mGluR-5, mGluR-2, mGluR-4 (mGluR-4a) (IC50 > 300 μM), NMDA and GluR (AMPA) (IC50 = 250 μM). 3...		GluR , NMDAR
T10831L	Cl-amidine hydrochloride		Apoptosis , PAD
	Cl-amidine hydrochloride is an orally active peptidylarginine deminase (PAD) inhibitor (IC50: 5.9 μM for PAD4). Cl-amidine hydrochloride induces apoptosis in cancer cells and it also induces microRNA (miR)-16 in vitro ca...		Apoptosis , PAD
T24816	SP-100030	SP100030,SP 100030	NF-κB
	SP-100030 is a dual inhibitor of NF-κB and activator protein-1 (AP-1), demonstrating potent inhibition with IC50 values of 50 nM for both. It effectively reduces the production of IL-2, IL-8, and TNF-alpha in Jurkat and ...		NF-κB
T3627	IQ-1S free acid	IQ-1,IQ-1S,IQ-1S (free acid)	NF-κB , JNK
	IQ-1S free acid (IQ-1S) is an effective and specific c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity. IQ-1S can reduce inflammation and cartilage loss associated with CIA and can se...		NF-κB , JNK
T0841	Bezafibrate	BM15075	PPAR
	Bezafibrate (BM15075) is an antilipemic agent that lowers CHOLESTEROL and TRIGLYCERIDES. It decreases LOW-DENSITY LIPOPROTEINS and increases HIGH-DENSITY LIPOPROTEINS.		PPAR
T23027	MRT-10		Hedgehog/Smoothened
	MRT-10 is a Smoothened (Smo) receptor antagonist.		Hedgehog/Smoothened
T1298	Clofibrate	Clofibrato,Clofibratum,Ethyl clofibrate	PPAR
	Clofibrate (Clofibrato) is an aryloxyisobutyric acid derivate with antihyperlipidemic activity.		PPAR
T3170	Troglitazone	CS-045,Romozin,Rezulin,Romglizone,Noscal,Prelay	Apoptosis , Ferroptosis , PPAR , Autophagy
	Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.		Apoptosis , Ferroptosis , PPAR , Autophagy
T10474	BAY-7598		Others
	BAY-7598 is a potent, selective, and orally bioavailable MMP12 inhibitor (IC50s: 0.085, 0.67, and 1.1 nM for human/murine/rat MMP12).		Others
T12590	Pyrindamycin A		Others
	Pyrindamycin A is an antibiotic that inhibits DNA synthesis,and shows antitumor activities against murine leukemia.		Others
T20338	Methopterin	NSC 107144,alpha-Methopterin,NSC-107144,10-Methylfolic acid,NSC107144
	Methopterin shows the activation and bone resorption function of murine osteoclasts.

Compounds

Tetrahydrozoline hydrochloride

T6703

Synonym: Murine Plus,Tetryzoline hydrochloride,Tyzine,Tetrahydrozoline HCl

Target: Adrenergic Receptor

Moloney murine leukemia virus RT

T79921

Synonym:

Target: DNA/RNA Synthesis

N-Acetyl-D-cysteine

T38155

Synonym:

Target: Reactive Oxygen Species

Voriconazole

T0120

Synonym: UK-109496

Target: Antifection, Antifungal

Flunixin meglumine

T1209

Synonym: Banamine,Finadyne,Flunixin meglumin

Target: Apoptosis, BMI-1

Synonym: 5-chloro-2-[4-(1,3-dioxobenzo[de]isoquinolin-2-yl)butylsulfamoyl]benzoic acid

Target: Glucagon Receptor

Target: Others, HIV Protease

17α-Hydroxyprogesterone acetate

T40380

Synonym:

Target: Others

Regorafenib monohydrate

T1792L

Synonym:

Target: Raf, VEGFR, c-RET, PDGFR, c-Kit, Autophagy

Mouse IgG2a kappa, Isotype Control

Target: Piezo Channel

3'-Azido-3'-deoxy-5-methylcytidine

T10133

Synonym:

Target: Antiviral, HIV Protease

Synonym: RBC 10,RBC-10

Synonym: V81444,ciforadenant

Target: Adenosine Receptor

ATN-161 trifluoroacetate salt

T10397

Synonym: ATN-161 TFA salt

Iα52 acetate(137756-45-7 free base)

Target: Others, Microtubule Associated, Src

Target: Apoptosis, Retinoid Receptor, Autophagy

Synonym: Janus-Associated Kinase Inhibitor I,JAK Inhibitor,CMP 6,JAK Inhibitor I

Target: Tyrosine Kinases, JAK

Avacopan

T8223

Synonym: CCX168

Target: Complement System

Anti-Mouse NK1.1 Antibody (PK136)

T78268

Synonym:

Target:

Aldoxorubicin hydrochloride

T11090L1

Synonym: Aldoxorubicin hydrochloride (1361644-26-9 Free base）

Target: Topoisomerase

Vadimezan

T6273

Synonym: DMXAA,5,6-Dimethylxanthenone-4-acetic Acid,NSC 640488,ASA-404

Target: Influenza Virus, VDA, STING, IFNAR

5-Hydroxymethyldeoxyuridine

Cl-amidine hydrochloride

T10831L

Synonym:

Target: Apoptosis, PAD

SP-100030

T24816

Synonym: SP100030,SP 100030

Target: NF-κB

IQ-1S free acid

T3627

Synonym: IQ-1,IQ-1S,IQ-1S (free acid)

Target: Hedgehog/Smoothened

Clofibrate

T1298

Synonym: Clofibrato,Clofibratum,Ethyl clofibrate

Target: PPAR

Troglitazone

T3170

Synonym: CS-045,Romozin,Rezulin,Romglizone,Noscal,Prelay

Target: Apoptosis, Ferroptosis, PPAR, Autophagy

Synonym: NSC 107144,alpha-Methopterin,NSC-107144,10-Methylfolic acid,NSC107144

Target:

カタログ番号	製品名	別名	ターゲット
T6S1027	Tussilagone		Others
	1. Tussilagone inhibits dendritic cell function through the induction of heme oxygenase-1. 2. Tussilagone has anti-cancer activity, might be a potential chemotherapeutic agent for the prevention and treatment of human co...		Others
T37341	N-Acetyltyramine		Antibacterial
	N-acetyltyramine is a metabolite of the biogenic amine tyramine . It enhances cytotoxicity of doxorubicin in resistant P388 murine leukemia cells with an IC50 value of 0.13 μg/ml compared with an IC50 value of 0.48 μg/ml...		Antibacterial
TN6369	Amurine	C09334	Antifungal
	Amurine (C09334) is an alkaloid isolated from P. stylatum with potential antibacterial activity.		Antifungal
T36115	Colchicoside	3-Demethylcolchicine glucoside	Others
	Colchicoside (3-Demethylcolchicine glucoside) is extracted from Gloriosa superba and shows efficacy in a murine model of pancreatic adenocarcinoma.		Others
T2978	Mogroside V		AMPK
	Mogroside V is a widely used sweetener, has in vitro AMPK activating effect, it also has anti-inflammatory potential in murine macrophages and a murine ear edema model, and has the potential to protect against LPS-induce...		AMPK
T3829	Ginsenoside F3		Others , IFNAR , Interleukin
	Ginsenoside-F3 has immunoenhancing activity by regulating production and gene expression of type 1, type 2 cytokines in murine spleen cells. Ginsenoside-F3 enhances the NF-kappaB DNA binding activity induced by ConA in m...		Others , IFNAR , Interleukin
TN1697	Glucosyringic acid		Immunology/Inflammation related
	Glucosyringic acid has immunosuppressive effect, it can inhibit the proliferation of murine B lymphocytes in vitro.		Immunology/Inflammation related
T7052	Gnetol		Tyrosinase , COX , HDAC , AChR
	Gnetol competitivity inhibits butyrylcholinesterase (IC50: 1.3 uM). Gnetol has a strong inhibitory effect on murine tyrosinase activity. Gnetol significantly suppresses melanin biosynthesis in murine B16 melanoma cells. ...		Tyrosinase , COX , HDAC , AChR
T6S1543	Dehydrodiisoeugenol		Others , NF-κB , COX , Antibacterial
	1. Dehydrodiisoeugenol has anti-inflammatory activity. (1). Dehydrodiisoeugenol inhibited the expression of the COX-2 in RAW264.7 murine macrophages stimulated with LPS. (2). Dehydrodiisoeugenol inhibited LPS-stimulated ...		Others , NF-κB , COX , Antibacterial
TN6339	(R)-5-Hydroxy-1,7-diphenylheptan-3-one	(5R)-Dihydroyashabushiketol	Others
	(R)-5-Hydroxy-1,7-diphenylheptan-3-one ((5R)-Dihydroyashabushiketol) is extracted from the rhizomes of Alpinia officinarum, a Chinese medicinal herb. (R)-5-Hydroxy-1,7-diphenylheptan-3-one inhibits melanogenesis in theop...		Others
T3S0645	N-trans-Feruloyltyramine	Feruloyltyramine,N-Feruloyltyramine,Moupinamide	Others , COX
	1. N-trans-Feruloyltyramine (Feruloyltyramine)(NTF) has hepatoprotective effect. 2. NTF has antioxidative activity against Aβ(1-42)-induced neuronal death. 3. NTF is likely to inhibit COX enzymes, thereby suppressing P-s...		Others , COX
T3S0153	Xanthatin		Apoptosis , VEGFR , Lipoxygenase , Wnt/beta-catenin , Antibacterial
	1. Xanthatin has cytotoxic activity. 2. Xanthatin has antibacterial and antifungal activies against MRSA. 3. Xanthatin may have therapeutic potential against NSCLC. 4. Xanthatin can inhibit murine melanoma B16-F1 cell pr...
T4S0350	Licochalcone B		Beta Amyloid , Others
	1. Licochalcone B (LCB) inhibits the proliferation of human malignant bladder cancer cell lines (T24 and EJ) in vitro and antitumor activity in vivo in MB49 (murine bladder cancer cell line) tumor model. 2. LCB and Licoc...		Beta Amyloid , Others
T3S0737	Flavokawain A	Flavokavain A	Apoptosis , p38 MAPK
	NSC-37445 has anti-tumor activity, such as inhibits growth of bladder tumor cells in a nude mice model , prevents the recurrence and progression of non-muscle-invasive urothelial cell carcinoma. NSC-37445 can significant...		Apoptosis , p38 MAPK
TCS2170	2,5-Dihydroxyacetophenone	Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP	ERK , NF-κB , Tyrosinase
	1. 2,5-Dihydroxyacetophenone (Quinacetophenone) possess anti-anxiety, and neuroprotective qualities. 2. 2,5-Dihydroxyacetophenone (Quinacetophenone) reatment can induce a sustained activation of JNK, ERK1/2, and p38 MAPK...		ERK , NF-κB , Tyrosinase
TN2029	P-Hydroxy-5,6-dehydrokawain	4'-Hydroxydehydrokawain	Others
	p-Hydroxy-5,6-dehydrokawain (4'-Hydroxydehydrokawain) is isolated from Kawain.		Others
TN6048	Zarzissine
	Zarzissine exhibits cytotoxicity against three human and murine tumor cell lines.
T40790	ω-Muricholic Acid
	ω-Muricholic acid (ω-MCA) is a murine-specific secondary bile acid.
TN5302	Withaperuvin C
	Withaperuvin C may have anti-inflammatory activity with lipopolysaccharide (LPS)-activated murine macrophage RAW 264.7 cells.
TN4047	Excisanin B		Others
	Excisanin B shows inhibitory effects on LPS-induced production of nitric oxide in murine macrophage RAW264.7 cells.		Others
TN1486	Chimonanthine		Others
	(-)-Chimonanthine (IC50 = 0.93 μM) shows potent inhibitory effects on melanogenesis in theophylline-stimulated murine B16 melanoma 4A5 cells.		Others
TN5212	Uvedalin		Others
	Uvedalin shows cytotoxicity against HeLa, HL-60, and Murine B16-F10 melanoma cell lines.		Others
TN3605	Casegravol		Others
	Casegravol shows antiproliferative activity against human gastric adenocarcinoma (MK-1), human uterus carcinoma (HeLa), and murine melanoma (B16F10) cells.		Others
T72578	Siegesbeckialide I
	Siegesbeckialide I effectively suppresses LPS-induced NO production in RAW264.7 murine macrophages by directly interacting with IKKα/β.
TN2813	23-deoxojessic acid		Others
	23-Deoxojessic acid possesses strong cytotoxicity towards highly liver metastatic murine colon 26-L5 carcinoma cells, with ED50 values equal to or less than 6 microM.		Others
TN4089	Futokadsurin C		Others
	Futokadsurin C can inhibit nitric oxide production by a murine macrophage-like cell line (RAW 264.7), which is activated by lipopolysaccharide and interferon-gamma.		Others
TN4050	Fargesone A		NOS
	Fargesone A shows inhibitory effects on nitric oxide (NO) production in the lipopolysaccharide plus interferon-gamma activated-murine macrophage cell line, J774.1.		NOS
T72858	Maydispenoid B
	Maydispenoid B, a potent immunosuppressor, effectively inhibits the proliferation of murine splenocytes activated by anti-CD3/anti-CD28 monoclonal antibodies (mAbs) and lipopolysaccharide.
TN1242	3,3'-Di-O-methylellagic acid	3,8-Di-O-methylellagic acid	Others , TNF , Antifection
	3,3'-Di-O-methylellagic acid reveals moderate antibacterial activity, it also shows strong DPPH radical scavenging activities with SC50 of 123.3 ug/mL. It has a lower capacity of stimulating murine peritoneal macrophages...		Others , TNF , Antifection
T38338	Quinolactacin A
	Quinolactactin A is a quinolone fungal metabolite originally isolated from Penicillium. It inhibits TNF production induced by LPS in murine peritoneal macrophages (IC50 = 12.2 μg/ml). It is not active against a variety o...
TN3869	Dimeric coniferyl acetate		Others
	Dimeric coniferyl acetate has anti-inflammary activity, it shows strong NO inhibition with IC50 values of 27.1 uM in lipopolysacchalide (LPS)-activated murine macrophage-like J774.1 cells. It exhibits significant inhibit...		Others
T36337	Burnettramic Acid A aglycone
	Burnettramic acid A aglycone is a fungal metabolite and an aglycone form of burnettramic acid A originally isolated fromA. burnettiithat has anticancer activity.1It is cytotoxic to NS-1 murine myeloma cells but not neona...
TN2106	Protodeltonin		BCL , PARP , Caspase
	Protodeltonin may have anti-thrombotic activity by both improving the anticoagulation activity and inhibiting platelet aggregation action. Protodeltonin can inhibit the proliferation of a panel of established human and m...		BCL , PARP , Caspase
TN4146	Glutinol acetate		TNF
	Glutinol acetate shows significant cytotoxic activity against four human cancer cell lines (HL-60, SK-OV-3, A549, and HT-29), with GI(50) in the range of 11.1-17.9microM; it also has anti-inflammatory effect, exhibits mo...		TNF
T36931	Penicillide
	Penicillide is a fungal metabolite originally isolated from Penicillium that has diverse biological activities. It is an inhibitor of calpain 2/m-calpain (IC50 = 7.1 μM) and acyl-coenzyme A:cholesterol acyltransferase (A...
T72857	Maydispenoid A
	Maydispenoid A, a potent immunosuppressive compound, effectively inhibits murine splenocyte proliferation activated by both anti-CD3/anti-CD28 monoclonal antibodies (mAbs) and lipopolysaccharide.
T35400	β-Muricholic Acid	β-MCA,5β-Cholanic Acid-3α,6β,7β-triol,β-Muricholic Acid
	β-Muricholic acid (β-MCA) is a murine-specific primary bile acid.[1],[2] Dietary administration of β-MCA reduces HMG-CoA reductase activity in liver microsomes from mice fed a high cholesterol and cholic acid diet.[3] Di...
T14317	Ar-Turmerone	(+)-ar-Turmerone	Others
	ar-Turmerone ((+)-ar-Turmerone) is a major bioactive compound of the herb Curcuma longa with anti-tumorigenesis and anti-inflammatory activities[1][2][3]. ar-Turmerone ((+)-ar-Turmerone) exerts positive modulation on mur...		Others
TN3461	Asebotin		Influenza Virus
	Asebotin shows anti-influenza A virus activity, it also possesses potent antiviral activity (100% inhibition at the concentration of 1 ug /mL) against highly pathogenic avian influenza strain H5N1. Asebotin can inhibit t...		Influenza Virus
TN5233	Villosin		Others
	Villosin exhibits potent cytotoxic activity , it may be used as a potential lead molecule for antitumor therapeutic development. Villosin shows inhibitory effects against nitric oxide production in LPS and IFN-γ-induced ...		Others
TN4623	Nagilactone C		Antifection
	Nagilactone C and phyllanthoside are novel protein synthesis inhibitors, they are specific for the eukaryotic translation apparatus, function in vivo and in vitro, and interfere with translation elongation. Nagilactone C...		Antifection
TN3979	Epiyangambin		PAFR
	Epiyangambin is a phytotoxic lignan, it shows inhibition of seed germination of Agrostis stolonifera cv. penncross (Poaceae) and inhibition of development of Lactuca sativa L. (Asteraceae) seedlings in a microassay using...		PAFR
TN4263	Isoangustone A		MMP , GSK-3 , NF-κB , ROS , Akt , PI3K , CDK , JNK
	Isoangustone A has antitumor activity, it can induce G1 cycle arrest in DU145 human prostate and 4T1 murine mammary cancer cells, it inhibits cell proliferation by targeting PI3K, MKK4, and MKK7 in human melanoma. Isoang...		MMP , GSK-3 , NF-κB , ROS , Akt , PI3K , CDK , JNK
T38097	Antibiotic PF 1052
	Antibiotic PF 1052 is a fungal metabolite originally isolated from Phoma.1,2 It is active against S. aureus, S. parvulus, and C. perfringens (MICs = 3.13, 0.78, and 0.39 μg/ml, respectively), among others.1 It inhibits n...
TN6062	1,3,9-Trimethyluric acid
	1,3,9-Trimethyluric acid exhibits in vitro cytotoxic activity against breast cancer (MCF-7), human neuroblastoma (SHSY5Y), human non-small cell lung cancer (A549) and human liver cancer (HEPG2) with IC50 value in the ran...
T75453	11-epi-Chaetomugilin I
	11-epi-Chaetomugilin I, a metabolite identified in Chaetomium globosum, demonstrates notable cytotoxic activity against several cell lines, including the murine P388 and L1210 leukemia cell lines, the human HL-60 leukemi...
T5157	9,13-Epidioxy-8(14)-abieten-18-oic acid		Others
	9,13β-Epidioxy-8(14)-abieten-18-oic acid has anti-inflammatory activities, it exhibits moderate activities on NO levels in LPS-stimulated murine microglia BV2 cells, with IC50 values of 57.3 ± 0.2 uM. It is also a potent...		Others
T75890	Conantokin G TFA
	Conantokin G TFA, a 17-amino-acid peptide, serves as a potent, selective, and competitive antagonist of N-Methyl-D-Aspartate (NMDA) receptors, effectively inhibiting NMDA-evoked currents in murine cortical neurons at an ...
TN2641	15-Methoxypinusolidic acid		ERK , IL Receptor , p38 MAPK , Calcium Channel , NOS , NF-κB , COX , JNK , NMDAR , PPAR
	15-Methoxypinusolidic acid has anti-inflammatory effects, it inhibits LPS-induced iNOS expression and NO production, independent on MAPK and NF-kappaB. 15-Methoxypinusolidic acid suppresses adipocyte differentiation thro...
T83862	Bactobolin A hydrochloride	BN-183B
	Bactobolin A, a microbial metabolite initially derived from Pseudomonas, exhibits both antibiotic and anticancer properties. It demonstrates activity against various bacteria including S. aureus, S. epidermidis, S. faeca...
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天然物製品

Target: Antibacterial

Synonym: 3-Demethylcolchicine glucoside

Target: Others, IFNAR, Interleukin

Glucosyringic acid

TN1697

Synonym:

Target: Immunology/Inflammation related

Gnetol

T7052

Synonym:

Target: Tyrosinase, COX, HDAC, AChR

Dehydrodiisoeugenol

T6S1543

Synonym:

Target: Others, NF-κB, COX, Antibacterial

(R)-5-Hydroxy-1,7-diphenylheptan-3-one

TN6339

Synonym: (5R)-Dihydroyashabushiketol

Target: Others

N-trans-Feruloyltyramine

T3S0645

Synonym: Feruloyltyramine,N-Feruloyltyramine,Moupinamide

Target: Apoptosis, VEGFR, Lipoxygenase, Wnt/beta-catenin, Antibacterial

Licochalcone B

T4S0350

Synonym:

Target: Beta Amyloid, Others

Flavokawain A

T3S0737

Synonym: Flavokavain A

Target: Apoptosis, p38 MAPK

2,5-Dihydroxyacetophenone

TCS2170

Synonym: Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP

Target: ERK, NF-κB, Tyrosinase

p-Hydroxy-5,6-dehydrokawain

TN2029

Synonym: 4'-Hydroxydehydrokawain

3,3'-Di-O-methylellagic acid

TN1242

Synonym: 3,8-Di-O-methylellagic acid

Target: Others, TNF, Antifection

Dimeric coniferyl acetate

TN3869

Synonym:

Target: Others

Burnettramic Acid A aglycone

Target: BCL, PARP, Caspase

Synonym: β-MCA,5β-Cholanic Acid-3α,6β,7β-triol,β-Muricholic Acid

Target:

ar-Turmerone

T14317

Synonym: (+)-ar-Turmerone

Target: Influenza Virus

Target: MMP, GSK-3, NF-κB, ROS, Akt, PI3K, CDK, JNK

1,3,9-Trimethyluric acid

TN6062

Synonym:

Target:

11-epi-Chaetomugilin I

T75453

Synonym:

Target:

9,13-Epidioxy-8(14)-abieten-18-oic acid

15-Methoxypinusolidic acid

TN2641

Synonym:

Target: ERK, IL Receptor, p38 MAPK, Calcium Channel, NOS, NF-κB, COX, JNK, NMDAR, PPAR

Bactobolin A hydrochloride

T83862

Synonym: BN-183B

Target:

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-00135	BDNF Protein, Human/Murine/Rat, Recombinant	Human,Mouse,Rat	E. coli
	Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. I...
TMPY-04552	AKT1 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	v-akt murine thymoma viral oncogene homolog 1 (AKT1), or protein kinase B-alpha (PKB-ALPHA) is a serine-threonine protein kinase, belonging to the Protein Kinase Superfamily. AKT1 is a major mediator of the responses to ...
TMPH-02984	Murine polyomavirus (MPyV) (strain Kilham) VP1 Protein (His)	MPyV	Baculovirus Insect Cells
	Murine polyomavirus (MPyV) (strain Kilham) VP1 Protein (His) is expressed in Baculovirus insect cells with C-6xHis tag. The predicted molecular weight is 42.5 kDa and the accession number is P24595.
TMPH-02986	Murine polyomavirus (MPyV) (strain Kilham) VP2 Protein (His)	MPyV	E. coli
	Murine polyomavirus (MPyV) (strain Kilham) VP2 Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 41.4 kDa and the accession number is P24596.
TMPY-04446	AKT3 Protein, Mouse, Recombinant (aa 106-479)	Mouse	Baculovirus Insect Cells
	AKT3 Protein, Mouse, Recombinant (aa 106-479) is expressed in Baculovirus insect cells. The predicted molecular weight is 43.4 kDa and the accession number is Q9WUA6-1.
TMPH-02985	Murine polyomavirus (MPyV) (strain Kilham) VP1 Protein (E. coli, His)	MPyV	E. coli
	Murine polyomavirus (MPyV) (strain Kilham) VP1 Protein (E. coli, His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 42.4 kDa and the accession number is P24595.
TMPH-02465	Moloney murine leukemia virus (MoMLV) (isolate Shinnick) Gag polyprotein (GST)	MoMLV	E. coli
	Moloney murine leukemia virus (MoMLV) (isolate Shinnick) Gag polyprotein (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 57.6 kDa and the accession number is P03332.
TMPY-04574	AKT3 Protein, Mouse, Recombinant (aa 106-479, His & GST)	Mouse	Baculovirus Insect Cells
	AKT3 Protein, Mouse, Recombinant (aa 106-479, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 71 kDa and the accession number is Q9WUA6-1.
TMPY-04387	AKT2 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	AKT (AK mouse plus Transforming or Thymoma) is a frequent oncogene expressed in most tissues which includes three isoforms AKT1, AKT2, and AKT3. Hyperactivation of AKT signaling is a central key in many human cancer prog...
TMPY-04553	AKT3 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	AKT3 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 81 kDa and the accession number is Q9Y243-1.
TMPY-01648	TREML2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Trem-like transcript 2 protein, also known as Triggering receptor expressed on myeloid cells-like protein 2, TREML2 and TLT2, is a single-pass type I membrane protein that contains one Ig-like V-type (immunoglobulin-like...
TMPJ-00011	CXCL2 Protein, Mouse, Recombinant	Mouse	E. coli
	C-X-C motif chemokine 2 (CXCL2,MIP-2) belongs to the intercrine alpha (chemokine CxC) family. It was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin...
TMPK-00760	IgG1 Fc Protein, Mouse, Recombinant	Mouse	HEK293 Cells
	Recombinant murine Fc fragment contains the hinge region, CH2, and CH3 region of the mouse IgG1 isotype. IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR) on...
TMPK-00470	PVRIG Protein, Mouse, Recombinant (hFc & Avi)	Mouse	HEK293 Cells
	Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG is an inducible checkpoint receptor and that targeting PVR...
TMPK-00471	PVRIG Protein, Mouse, Recombinant (hFc & Avi), Biotinylated	Mouse	HEK293 Cells
	Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG is an inducible checkpoint receptor and that targeting PVR...
TMPK-01414	Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer Protein, Mouse, MHC (His & Avi)	Mouse	HEK293 Cells
	Qa-1b binds a peptide (AMAPRTLLL), referred to as Qdm (for Qa-1 determinant modifier), derived from the signal sequence of murine class Ia molecules. This peptide binds with high affinity and accounts for almost all of t...
TMPK-00974	SP17 Protein, Human, Recombinant (His)	Human	E. coli
	Sperm protein 17 (Sp17) is a highly conserved mammalian protein characterized in rabbit, mouse, monkey, baboon, macaque, human testis and spermatozoa. mRNA encoding Sp17 has been detected in a range of murine and human s...
TMPK-01262	CD200R1/CRTR2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell surface receptor, CD200R, expressed on cells of the myeloid...
TMPK-00624	CD200R1/CRTR2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell surface receptor, CD200R, expressed on cells of the myeloid...
TMPK-00622	CD200R1/CRTR2 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell surface receptor, CD200R, expressed on cells of the myeloid...
TMPJ-00692	GAS7 Protein, Human, Recombinant (His)	Human	E. coli
	Growth Arrest-Specific Protein 7 (GAS7) is expressed primarily in terminalaly differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. GAS7 may play a role in neuronal development by promoting ...
TMPK-00623	CD200R1/CRTR2 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell surface receptor, CD200R, expressed on cells of the myeloid...
TMPK-01035	SP17 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Sperm protein 17 (Sp17) is a highly conserved mammalian protein characterized in rabbit, mouse, monkey, baboon, macaque, human testis and spermatozoa. mRNA encoding Sp17 has been detected in a range of murine and human s...
TMPJ-00079	IL-11 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Interleukin-11(IL-11) is a secreted protein and belongs to the IL-6 superfamily. IL-11 has been demonstrated to improve platelet recovery after chemotherapy-induced thrombocytopenia, induceacute phase proteins, modulate ...
TMPJ-00451	IL-16 Protein, Human, Recombinant	Human	E. coli
	Interleukin-16 (IL-16) is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, human IL-16 e...
TMPJ-01079	TFF2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Recombinant Murine TFF-2 is an 11.9 kDa polypeptide of 106 amino acid residues, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds. The Trefoil Factor peptides (TFF1, T...
TMPY-03969	SUSD4 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	SUSD4, also known as sushi domain-containing protein 4, is a hypothetical cell surface protein whose tissue distribution and function are completely unknown. SUSD4 is detectable in murine brains, eyes, spinal cords, and ...
TMPY-00641	LEC/CCL16 Protein, Human, Recombinant (His)	Human	E. coli
	CCL16, a chemokine poorly characterized at the functional level. Human CCL16 is a member of the CC family, and its gene maps to human chromosome 17q. In the mouse, only a pseudogene has been identified to date. CCL16 is ...
TMPK-01385	CRTAM Protein, Canine, Recombinant (His)	Canine	HEK293 Cells
	Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of I...
TMPK-00971	CRTAM Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of I...
TMPY-05014	INSL6 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	INSL6 (Insulin-Like 6) is a Protein Coding gene. An important paralog of this gene is RLN1. The protein encoded by this gene contains a classical signature of the insulin superfamily and is significantly similar to relax...
TMPY-02891	PSG6 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	PSG6 is a pregnancy-specific glycoprotein(PSG). PSGs are secreted proteins produced by the rodent and primate placenta and play a critical role in pregnancy success. The levels of PSGs are highest during the third trimes...
TMPY-02117	Marapsin Protein, Human, Recombinant (His)	Human	HEK293 Cells
	The name "Pancreasin" because it is transcribed strongly in the pancreas. This secreted, tryptic serine protease, also known as Marapsin or PRSS27 (Protease, serine, 27), is a member of the peptidase S1 family. Pancreasi...
TMPY-02838	FGFBP3 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	FGFBP3 is a member of the fibroblast growth factor-binding protein family. Members of this family binds and activates FGF-1 and FGF-2, thereby contributing to tumor angiogenesis. Fibroblast growth factors (FGFs) are impo...
TMPY-00963	ASAH2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	ASAH2 (N-acylsphingosine amidohydrolase 2), also known as neutral ceramidase, is a type II integral membrane protein that can be cleaved to produce a soluble secreted protein. The enzyme is abundant in the brush border m...
TMPY-02597	IL-37 Protein, Human, Recombinant	Human	E. coli
	Interleukin 1 family member 7, or interleukin 37 (IL1F7 / IL37 / IL-1H4) is a secretory protein belonging to the Interleukin 1 family. IL-1F7 was localized in human peripheral monocytic cells. It has been localized the e...
TMPY-00004	CD28 Protein, Rat, Recombinant (hFc)	Rat	HEK293 Cells
	CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and ...
TMPJ-00674	RANK/TNFRSF11A Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Receptor activator of NF-κB(RANK,TNFRSF11A) belongs to one member of tumor necrosis factor receptor family.It is a receptor for TNFSF11/RANKL/TRANCE/OPGL. This gene encodes a type 1 membrane protein with a 30 amino acid...
TMPY-03504	CBFB Protein, Human, Recombinant (His)	Human	E. coli
	CBFB is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and os...
TMPY-01909	Elafin Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Elafin, also known as Elastase-specific inhibitor, Peptidase inhibitor 3, Protease inhibitor WAP3, Skin-derived antileukoproteinase, WAP four-disulfide core domain protein 14, PI3, WAP3 and WFDC14, is a secreted protein ...
TMPY-04554	JNK1 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	Mitogen-activated protein kinase 8 (MAPK8), also known as JNK1, is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellula...
TMPY-01416	OLFM4 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Olfactomedin-4, also known as G-CSF-stimulated clone 1 protein, Antiapoptotic protein GW112, and OLFM4, is a secreted protein that contains one olfactomedin-like domain. The OLFM4 gene was recently reported to inhibit va...
TMPY-01249	Cathepsin V Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cathepsin V (CTSV), also known as Cathepsin L2, CTSL2, and CATL2, is a member of the peptidase C1 family. It is predominantly expressed in the thymus and testis. Cathepsin V is also expressed in corneal epithelium, and t...