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カタログ番号	製品名	別名	ターゲット
T8348	Phentolamine		Adrenergic Receptor
	Phentolamine mesylate is an alpha-1 and alpha-2 selective adrenergic receptor antagonist		Adrenergic Receptor
T8580	Bupranolol		Adrenergic Receptor
	Bupranolol is an antagonist of β2-adrenergic receptor and has been used for angina pectoris, hypertension, glaucoma, cardiac arrhythmia and as an antithrombotic.		Adrenergic Receptor
T9732	VY-3-135		Fatty Acid Synthase
	VY-3-135 is a metastasis inhibitor and an acetyl-CoA synthetase 2 (ACSS2) modulator.		Fatty Acid Synthase
T1292	Tiapride hydrochloride		Dopamine Receptor
	Tiapride is a selective blocker of D2/3 dopamine receptors in the brain. It is used in the therapy of various psychiatric and neurological disorders containing dyskinesia, negative symptoms of psychosis, alcohol withdraw...		Dopamine Receptor
T9565	OSBPL7-IN-1		Others
	OSBPL7-IN-1 is an orally active inhibitor of oxysterol binding protein like 7 (OSBPL7). OSBPL7-IN-1 promotes an increase of ABCA1 at the plasma membrane without affecting mRNA expression[1].		Others
T8734	Choline		Others
	Choline is a ubiquitous water soluble nutrient, often associated with the B vitamins		Others
T34896	Tofisopam	Emandaxin,Grandaxin	Others
	Tofisopam (Grandaxin) is a 2,3-benzodiazepine compound with anxiolytic activity that can be taken orally.		Others
T9805	BAY 2666605		PDE
	BAY 2666605 is an orally active inhibitor of PDE3A and PDE3B with IC50s of 87 nM and 50 nM, respectively. BAY 2666605 has anticancer effects.		PDE
T9164	BMS-986242	BMS986242	IDO , Indoleamine 2,3-Dioxygenase (IDO)
	BMS-986242 is an orally active, potent and selective inhibitor of indoleamine-2,3-dioxygenase 1 (IDO1), and it can be used for the research of cancer.		IDO , Indoleamine 2,3-Dioxygenase (IDO)
T9590	T-1095		SGLT , transporter
	T-1095 is an inhibitor of renal glucose reabsorption and the expression of Na+-glucose cotransporters (SGLTs) and facilitative glucose transporter 2 (GLUT2).		SGLT , transporter
T9977	SGK1-IN-4		SGK
	SGK1-IN-4 is a selective inhibitor of SGK1 and can be used in studies about osteoarthritis.		SGK
T2629	UNC2881		TAM Receptor
	UNC2881 is a specific Mer tyrosine kinase inhibitor (IC50: 4.3 nM). It is about 83- and 58-fold higher selectivity than Axl and Tyro3, respectively.		TAM Receptor
T7686	Ramiprilat		RAAS
	Ramiprilat is an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.		RAAS
T8581	Flecainide hydrochloride		Others
	Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias.		Others
T2678	LB42708		Transferase
			Transferase
T36670	JNJ-67856633		MALT
	JNJ-67856633 is an orally active, first-in-class, potent, selective and allosteric inhibitor of MALT1 protease . JNJ-67856633 lead to tumor stasis in some cases.		MALT
T17158	Trans-AUCB	t-AUCB	Epoxide Hydrolase
	trans-AUCB (t-AUCB) is an effective and selective soluble epoxide hydrolase inhibitor (IC50s: 1.3 nM, 8 nM, 8 nM for hsEH, mouse sEH and rat sEH, respectively).		Epoxide Hydrolase
T22304	Desciclovir	BW A515U,6-Deoxyacyclovir,DCV	Antifection
	Desciclovir (DCV), a prodrug of the antiherpetic agent acyclovir (ACV), is converted in humans to ACV, presumably by xanthine oxidase.		Antifection
T7503	Upadacitinib	ABT-494	JAK
	Upadacitinib (ABT-494) (ABT-494) is a selective Janus kinase (JAK) 1 inhibitor, which is being studied for the treatment of several autoimmune disorders in the IC50 of 43 nM.		JAK
T28167	NGB 2904	NGB2904 HCl,NGB-2904,NGB2904	Others , Dopamine Receptor , 5-HT Receptor
	NGB 2904 is a potent and selective antagonist of dopamine D3 receptor (Ki values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D3, D2, 5-HT2, α1, D4, D1 and D5 receptors respectively). NGB2904 potently antag...		Others , Dopamine Receptor , 5-HT Receptor
T21593	AAL-993		VEGFR
	AAL-993 is a potent VEGFR inhibitor with IC50s of 130 nM, 23 nM and 18 nM for VEGFR1, VEGFR2 and VEGFR3, respectively. AAL993 has a weak inhibitory effect on other tyrosine kinases. AAL993 also shows potent antiangiogeni...		VEGFR
T4628	Seladelpar	MBX 8025	PPAR
	Seladelpar (MBX 8025) has been used in trials studying the treatment of Hyperlipidemia.		PPAR
T60024	CFT7455	Cemsidomide	Ligand for E3 Ligase
	CFT7455 (Cemsidomide) is an anti-cancer agent showing high affinity to the cereblon E3 ligase with a Kd of 0.9 nM. CFT7455 is an orally active degrader of zinc finger transcription factors Ikaros (IKZF1), and Aiolos (IKZ...		Ligand for E3 Ligase
T9627	PHD-1-IN-1		HIF/HIF Prolyl-Hydroxylase
	PHD-1-IN-1 is a potent inhibitor of hypoxia-inducible factor prolylhydroxylase domain-1 (PHD-1) enzyme(IC50 = 0.034 μM).		HIF/HIF Prolyl-Hydroxylase
T2578	Didanosine	ddI,2',3'-Dideoxyinosine	HIV Protease , Reverse Transcriptase
	Didanosine (ddI) is a nucleoside reverse transcriptase inhibitor analog of adenosine (IC50: 0.49 μM).		HIV Protease , Reverse Transcriptase
T0389	Dabigatran etexilate	BIBR 1048	Thrombin
	Dabigatran etexilate (BIBR 1048) is a thrombin inhibitor, which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation.		Thrombin
T1448	Dasatinib	BMS-354825	Apoptosis , Bcr-Abl , Src , c-Kit , Autophagy
	Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive. Dasatinib has antitumor activity and is used in the treatment of leukemia and ly...		Apoptosis , Bcr-Abl , Src , c-Kit , Autophagy
T22675	Co 102862	V 102862	Others , Sodium Channel
	Co 102862 is a voltage-gated sodium channel blocker. Co 102862 can be used for anticonvulsant studies.		Others , Sodium Channel
T21976	ONO-8130		Prostaglandin Receptor
	ONO-8130 is an orally available antagonist of EP1 receptor.		Prostaglandin Receptor
T1072	Loxeen	Pridinol methanesulfonate	AChR
	Loxeen (Pridinol methanesulfonate) is used as an anticholinergic and as an antiparkinsonian agent.		AChR
T21696	SC-57461A		Aminopeptidase
	SC 57461A is a potent and specific leukotriene A4 hydrolase (LTA4H) inhibitor.		Aminopeptidase
T22436	Takeda-6d		VEGFR
	Takeda-6d, a novel, potent DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor, inhibits B-RAF and VEGFR2 with IC50 of 7.0nM and 2.2nM.		VEGFR
T2316	Omarigliptin	MK-3102	Proteasome , DPP-4
	Omarigliptin (MK-3102) has been used in trials studying the treatment of Type 2 Diabetes Mellitus and Chronic Renal Insufficiency.		Proteasome , DPP-4
T7811	Pilsicainide HCl	SUN 1165	Sodium Channel
	Pilsicainide HCl (SUN 1165) is a pure sodium channel blocker		Sodium Channel
T1613	Hydralazine hydrochloride	Hydralazine HCl,Apresoline	MAO , HIF/HIF Prolyl-Hydroxylase
	Hydralazine hydrochloride (Apresoline) is the hydrochloride salt of hydralazine, a phthalazine derivative with antihypertensive and potential antineoplastic activities. Hydralazine alters intracellular calcium release an...		MAO , HIF/HIF Prolyl-Hydroxylase
T30937	Cimicoxib	UR-8880,UR8880,trade name: Cimalgex	COX
	Cimicoxib (UR8880) is a potent and selective inhibitor of COX-2 with anti-inflammatory and analgesic activity.		COX
T0692	Allopurinol	Zyloric,Zyloprim,Lopurin	ROS , Xanthine Oxidase
	Allopurinol (Zyloric) is a Xanthine Oxidase Inhibitor. The mechanism of action of allopurinol is as a Xanthine Oxidase Inhibitor.		ROS , Xanthine Oxidase
T40187	GNF2133		DYRK
	GNF2133 is an effective and selective inhibitor of DYRK1A with IC50s of 6.2 nM. GNF2133 can be used in studies about type 1 diabetes.		DYRK
T5329	Trandolapril		Angiotensin-converting Enzyme (ACE)
	Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that is hydrolysed to the active diacid trandolaprilat.		Angiotensin-converting Enzyme (ACE)
T21314	Amsilarotene	TAC-101,TAC 101,TAC101	CDK
	Amsilarotene (TAC101) inhibits the phosphorylation of retinoblastoma gene product (RB) and increases the presence of 2 cyclin-dependent kinases (CDK) inhibitors resulting in cell cycle arrest. This agent also causes a cy...		CDK
T0383	Fenspiride hydrochloride	Fenspiride HCl,Pneumorel,Fluiden,Decaspiride	Adrenergic Receptor , PDE , Histamine Receptor
	Fenspiride hydrochloride (Decaspiride) , an oxazolidinone spiro compound, is a drug used in the therapy of certain respiratory diseases. It is approved for use in Russia for the therapy of chronic and acute inflammatory ...		Adrenergic Receptor , PDE , Histamine Receptor
T7511	Cyclo(his-pro)		NF-κB , Endogenous Metabolite
	Cyclo(his-pro) is an endogenous cyclic dipeptide that exerts oxidative damage protection by selectively activating the transcription factor Nrf2 signalling pathway.		NF-κB , Endogenous Metabolite
T16813	RX-3117	fluorocyclopentenylcytosine,TV-1360	Nucleoside Antimetabolite/Analog
	RX-3117 (fluorocyclopentenylcytosine) is a novel a cytidine analog. RX-3117 displays anticancer activity in several cancer cell lines, including gemcitabine-resistant variants.		Nucleoside Antimetabolite/Analog
T29856	Aleplasinin	PAZ 417,PAZ417,PAZ-417	PAI-1
	Aleplasinin (PAZ 417) is a selective and orally active inhibitor of Plasminogen activator inhibitor-1(PAI-1) and a key negative regulator of the fibrinolytic system. Aleplasinin can be used in Alzheimer's disease studies...		PAI-1
T3716	Rolapitant	SCH619734	Neurokinin receptor
	Rolapitant (SCH619734) Hydrochloride is the hydrochloride salt form of rolapitant, an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. ...		Neurokinin receptor
T9831	MKC-1	Ro-31-7453	Apoptosis , Akt , Microtubule Associated , mTOR
	MKC-1 (Ro-31-7453) is an orally bioavailable, small-molecule, bisindolylmaleimide cell cycle inhibitor with potential antineoplastic activity. MKC-1 and its metabolites inhibit tubulin polymerization, blocking the format...		Apoptosis , Akt , Microtubule Associated , mTOR
T2171	SEW2871	SEW2871	S1P Receptor , LPL Receptor
	SEW 2871 is an orally available, highly selective S1P1 agonist with an EC50 of 13.8 nM.It reduces the number of lymphocytes in the blood and is used in studies related to diabetes, Alzheimer's disease, liver fibrosis, an...		S1P Receptor , LPL Receptor
T0682	Lamivudine	GR109714X,BCH-189	HIV Protease , Reverse Transcriptase
	Lamivudine (BCH-189) is a reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat HIV disease.		HIV Protease , Reverse Transcriptase
T6048	Dalcetrapib	JTT-705,RO4607381	CETP
	Dalcetrapib (RO4607381), a rhCETP inhibitor (IC50=0.2 μM), increases the plasma HDL cholesterol.		CETP
T5133	Dabigatran Etexilate Mesylate	BIBR 1048MS,Dabigatran etexilate methanesulfonate	Thrombin
	Dabigatran Etexilate Mesylate (BIBR 1048MS) is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor (DTI, Ki: 4.5 nM).		Thrombin

Compounds

Phentolamine

T8348

Synonym:

Target: Adrenergic Receptor

Bupranolol

T8580

Synonym:

Target: Adrenergic Receptor

VY-3-135

T9732

Synonym:

Target: Fatty Acid Synthase

Tiapride hydrochloride

T1292

Synonym:

Target: Dopamine Receptor

Synonym: Emandaxin,Grandaxin

Target: IDO, Indoleamine 2,3-Dioxygenase (IDO)

T-1095

T9590

Synonym:

Target: SGLT, transporter

Flecainide hydrochloride

Target: Epoxide Hydrolase

Desciclovir

T22304

Synonym: BW A515U,6-Deoxyacyclovir,DCV

Synonym: NGB2904 HCl,NGB-2904,NGB2904

Target: Others, Dopamine Receptor, 5-HT Receptor

Target: Ligand for E3 Ligase

PHD-1-IN-1

T9627

Synonym:

Target: HIF/HIF Prolyl-Hydroxylase

Didanosine

T2578

Synonym: ddI,2',3'-Dideoxyinosine

Target: HIV Protease, Reverse Transcriptase

Target: Apoptosis, Bcr-Abl, Src, c-Kit, Autophagy

Co 102862

T22675

Synonym: V 102862

Target: Others, Sodium Channel

ONO-8130

T21976

Synonym:

Target: Prostaglandin Receptor

Loxeen

T1072

Synonym: Pridinol methanesulfonate

Target: Aminopeptidase

Target: Proteasome, DPP-4

Pilsicainide HCl

T7811

Synonym: SUN 1165

Target: Sodium Channel

Hydralazine hydrochloride

T1613

Synonym: Hydralazine HCl,Apresoline

Target: MAO, HIF/HIF Prolyl-Hydroxylase

Cimicoxib

T30937

Synonym: UR-8880,UR8880,trade name: Cimalgex

Target: COX

Allopurinol

T0692

Synonym: Zyloric,Zyloprim,Lopurin

Target: ROS, Xanthine Oxidase

Target: Angiotensin-converting Enzyme (ACE)

Amsilarotene

T21314

Synonym: TAC-101,TAC 101,TAC101

Target: CDK

Fenspiride hydrochloride

T0383

Synonym: Fenspiride HCl,Pneumorel,Fluiden,Decaspiride

Target: Adrenergic Receptor, PDE, Histamine Receptor

Cyclo(his-pro)

T7511

Synonym:

Target: NF-κB, Endogenous Metabolite

RX-3117

T16813

Synonym: fluorocyclopentenylcytosine,TV-1360

Target: Nucleoside Antimetabolite/Analog

Aleplasinin

T29856

Synonym: PAZ 417,PAZ417,PAZ-417

Target: Neurokinin receptor

MKC-1

T9831

Synonym: Ro-31-7453

Target: Apoptosis, Akt, Microtubule Associated, mTOR

SEW2871

T2171

Synonym: SEW2871

Target: S1P Receptor, LPL Receptor

Lamivudine

T0682

Synonym: GR109714X,BCH-189

Target: HIV Protease, Reverse Transcriptase

Dalcetrapib

T6048

Synonym: JTT-705,RO4607381

Target: CETP

Dabigatran Etexilate Mesylate

T5133

Synonym: BIBR 1048MS,Dabigatran etexilate methanesulfonate

Target: Thrombin

カタログ番号	製品名	別名	ターゲット
T3858	Macranthoidin A		Others
	Macranthoidin A has anti-inflammation activity.		Others
T4S1114	Dryocrassin ABBA	Dryocrassin	Influenza Virus , Antibacterial
	Dryocrassin ABBA (Dryocrassin) is a flavonoid natural product derived from Dryopteris crassirhizoma, with antiviral and antibacterial activities.		Influenza Virus , Antibacterial
T1560	Prednisolone	Predonine,Hydroretrocortine,Metacortandralone	Glucocorticoid Receptor , Endogenous Metabolite
	Prednisolone (Hydroretrocortine) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.		Glucocorticoid Receptor , Endogenous Metabolite
T5784	Topotecan	NSC 609669,SKF 104864A	Topoisomerase , Autophagy
	Topotecan (NSC-609669) is a Topoisomerase I inhibitor,and is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases.		Topoisomerase , Autophagy
T1611	Isotretinoin	13-cis-Retinoic acid	Retinoid Receptor , Endogenous Metabolite , Autophagy
	Isotretinoin (13-cis-Retinoic acid) binds to and activates nuclear retinoic acid receptors (RARs); activated RARs serve as transcription factors that promote cell differentiation and apoptosis. Isotretinoin is a naturall...		Retinoid Receptor , Endogenous Metabolite , Autophagy
T1326	Gentamicin sulfate	SCH9724,Gentamycin sulfate,NSC-82261	ribosome , DHFR , Antibacterial , Antibiotic
	Gentamicin sulfate (SCH9724) is a wide-spectrum, aminoglycoside antibiotic used to inhibit protein synthesis in sensitive organisms.		ribosome , DHFR , Antibacterial , Antibiotic
T5283	NADH disodium salt	Disodium NADH,NADH, disodium salt hydrate	Others , Endogenous Metabolite
	NADH disodium salt hydrate is a coenzyme of oxidoreductase. NADH acts as a regenerative electron donor during catabolic processes including glycolysis, the citric acid cycle and beta-oxidation.		Others , Endogenous Metabolite
T0974	Novobiocin Sodium	Albamycinsodium,Cathomycin,Albamycin	Potassium Channel , DNA gyrase , Topoisomerase , Antibacterial , Antibiotic , ABC , Autophagy
	Novobiocin Sodium (Albamycinsodium) binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound derived from Streptomyces niveus. It has a chemical structure sim...
T2719	Succinic acid	Asuccin,Amber acid,1,2-Ethanedicarboxylic acid,Wormwood acid,Butanedioic acid,1,4-Butandioic Acid	Endogenous Metabolite
	Succinic acid (1,2-Ethanedicarboxylic acid) is a water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is al...		Endogenous Metabolite
T6194	Fidaxomicin	Tiacumicin B,OPT-80,Clostomicin B1,PAR-101	Apoptosis , DNA/RNA Synthesis , Antibacterial , Antibiotic
	Fidaxomicin (Tiacumicin B) is a semisynthetic macrolide antibiotic used to treat Clostridium difficile-associated diarrhea in adults. Fidaxomicin has minimal systemic absorption and has not been linked to serum enzyme el...		Apoptosis , DNA/RNA Synthesis , Antibacterial , Antibiotic
T3417	Amentoflavone	Didemethyl-ginkgetin,Amenthoflavone,3',8''-Biapigenin	Apoptosis , P450 , Phospholipase , Reactive Oxygen Species , Opioid Receptor , COX , Antibacterial , RSV , Antifungal
	Amentoflavone (3',8''-Biapigenin), as a potent inhibitor of CYP3A4 and CYP2C9, can interact with many other medications. CYP3A4 and CYP2C9 are proteins used for drug metabolism in the body. Amentoflavone also is an inhib...
T2755	Rhoifolin	Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside	Others , p38 MAPK , NF-κB , transporter , IGF-1R , Autophagy
	Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.
T3912	Saikosaponin B1		Others
	Saponin activator. Activates release of Prostaglandin E2 in vitro. Anti-inflammatory agent. Orally active. Active in vivo and in vitro.		Others
T3014	(±)-Abscisic acid	Abscisic acid,Dormin,Abscisinsaeure	Others
	(±)-Abscisic acid is an orally active phytohormone also found in animals. It regulates blood glucose in mammals.		Others
T13092	Tauro-Obeticholic acid		FXR
	Tauro-Obeticholic acid is an active Obeticholic acid metabolite. Obeticholic acid is an orally bioavailable agonist of farnesoid-X receptor (FXR).		FXR
TQ0288	Hexahydrocurcumin		Reactive Oxygen Species , ROS , COX
	Hexahydrocurcumin is a selective, orally active COX-2 inhibitor and inactive against COX-1.		Reactive Oxygen Species , ROS , COX
T4912	Jatrorrhizine chloride	Yatrorhizine chloride,Neprotine chloride	Others , 5-HT Receptor , OCT , Antibacterial , AChE
	Jatrorrhizine chloride (Neprotine chloride) is a potent and orally active uptake-2 transporter inhibitor. It exhibits a critical neuroprotective role in H2O2-induced apoptosis via inhibition of the MAPK pathway in HT22 h...		Others , 5-HT Receptor , OCT , Antibacterial , AChE
TN2429	Capsiate		Antioxidant , TRP/TRPV Channel
	Capsiate is an orally active TRPV1 agonist, a non-irritating capsaicin analog that acts as an antiallergic agent with anti-inflammatory, antioxidant, hypoglycemic, and inhibitory angiogenic activity.		Antioxidant , TRP/TRPV Channel
T7064	Valproic Acid	Sodium valproate,2-Propylpentanoic Acid,VPA,Depakine,2-Propylvaleric Acid	Mitophagy , Gamma-secretase , HIV Protease , GABA Receptor , Sodium Channel , HDAC , Autophagy
	Valproic Acid (2-Propylpentanoic Acid) is an HDAC inhibitor that inhibits HDAC1 activity, induces HDAC2 degradation, and is orally active. Valproic Acid can be used in epilepsy and bipolar disorder research.
T11060	DMAPT	Dimethylamino Parthenolide	NF-κB
	DMAPT (Dimethylamino Parthenolide) is a water-soluble analogue of Parthenolide (PTL). It is an orally active NF-κB inhibitor with an LD50 of 1.7 μM on primary acute myeloid leukemia cells.		NF-κB
T0948L	Corticosterone	17-Deoxycortisol,11β,21-Dihydroxyprogesterone,Kendall's compound B,Corticosterone (From plants)	Glucocorticoid Receptor , Endogenous Metabolite
	Corticosterone (Kendall's compound B) is an adrenocortical steroid with salocorticoid and glucocorticoid activity that is orally active. Corticosterone is involved in the regulation of energy, immune responses, and stres...		Glucocorticoid Receptor , Endogenous Metabolite
T3S2007	MRE-269	MRE 269,ACT-333679,MRE269	Prostaglandin Receptor
	MRE-269 (ACT-333679) is an orally available and long-acting prostacyclin receptor agonist prodrug. MRE-269(ACT-333679) is used for the treatment of pulmonary arterial hypertension. MRE-269(ACT-333679) is an active metabo...		Prostaglandin Receptor
TJS2216	Aurantiamide acetate	Asperglaucide	Cysteine Protease
	Aurantiamide acetate (Asperglaucide) was isolated from the fermentation broth of Aspergillus penicilloides for the first time. Aurantiamide acetate is a selective and orally active cathepsin inhibitor. Aurantiamide aceta...		Cysteine Protease
T3859	Isomucronulatol	7,2'-Dihydroxy-3',4'-dimethoxyisoflavan	Others
	Glycerol Tridecanoate is an orally active precursor (DA precursor) of caprylic acid that can be hydrolyzed to caprylic acid. It is a major component of medium chain triglycerides (MCT) and has antiandrogenic and antihype...		Others
T16442	PCO371	2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-	Thyroid hormone receptor(THR)
	PCO371 (2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-) is an orally active full agonist of parathyroid hormon...		Thyroid hormone receptor(THR)
T0883	Tramiprosate	Homotaurine,3-Amino-1-propanesulfonic acid,Alzhemed	Beta Amyloid , GABA Receptor
	Tramiprosate (Alzhemed) is an orally active, blood-brain-barrier-crossing, naturally occurring amino acid found in a variety of red seaweeds that binds soluble Aβ and maintains it in a non-protofibrillar form.It is a GAB...		Beta Amyloid , GABA Receptor
T2986	Jatrorrhizine hydrochloride		Others , 5-HT Receptor , Antibacterial , AChE
	Jatrorrhizine hydrochloride is a compound extracted from the roots of Berberis vulgaris with neuroprotective, antimicrobial, antiplasmodial, and antioxidant activities.Jatrorrhizine hydrochloride is an orally active and ...		Others , 5-HT Receptor , Antibacterial , AChE
T5227	Tricaprin	Tridecanoin,Glyceryl tridecanoate,Glycerol Tridecanoate,TG(10:0/10:0/10:0),Glycerol tricaprate	Others , Endogenous Metabolite
	Glycerol Tridecanoate is an orally active precursor (DA precursor) of caprylic acid that can be hydrolyzed to caprylic acid. It is a major component of medium chain triglycerides (MCT) and has antiandrogenic and antihype...		Others , Endogenous Metabolite
T40615	N,N'-Dimethylthiourea	DMTU	Antioxidant
	N,N'-Dimethylthiourea (DMTU) (DMTU), isolated from Allii Sativi Bulbus, is an orally active scavenger of hydroxyl radical ( OH) and blocks OH production by activated neutrophils in vitro. N,N'-Dimethylthiourea protects a...		Antioxidant
T6491	(-)-(S)-Equol	(−)-Equol,Equol,4',7-Dihydroxyisoflavan,4',7-Isoflavandiol	Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Endogenous Metabolite
	(-)-(S)-Equol (4',7-Dihydroxyisoflavan) is an orally bioavailable, non-steroidal estrogen naturally produced by the metabolism of the isoflavonoid daidzein by human intestinal microflora, with potential chemoprotective a...
T1678	Nystatin	Stamycin,Fungicidin,Nystavescent	Apoptosis , Antibiotic , Antifungal
	Nystatin (Fungicidin) is a topical and oral antifungal agent with activity against many species of yeast and candida albicans, which is used largely to treat skin and oropharyngeal candidiasis.		Apoptosis , Antibiotic , Antifungal
T4954L	Smilagenin	PYM50028,Cogane,AI3-44895,PYM 50028
	Smilagenin is an orally active inducer of nonpeptide neurotrophic factor. It also prevents and reverses neuronal damage induced by MPP+ in mesencephalic neurons, and by MPTP in a mouse model of Parkinson's disease.
T68746	Chaetochromin		Others
	Chaetochromin also known as 4548-G05 and NSC 345647, is an orally active, small-molecule, selective agonist of the insulin receptor. It has potent and long-lasting antidiabetic activity in vivo in mice.		Others
T38557	Chitotriose trihydrochloride		Others
	Chitotriose trihydrochloride is an orally active chitooligosaccharide known for its antioxidant properties. It effectively inhibits the hydroxylation of benzoate to salicylate by H 2 O 2 in the presence of Cu 2+, with an...		Others
T60741	Dihydrocapsiate		Others
	Dihydrocapsiate is a compound of capsinoid family that can be used in metabolism diseas research. Dihydrocapsiate is an orally active agonist of TRPV1 [1].		Others
T61171	Cyclo(his-pro) TFA		Others
	Cyclo(his-pro) TFA, an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone, has shown inhibitory effects on NF-κB nuclear accumulation. Additionally, it possesses the ability to cross the...		Others
T75508	Bleomycin A5		Others
	Bleomycin A5 (Pingyangmycin), a glycopeptide antibiotic that is orally active, functions as an antineoplastic agent, an apoptosis inducer, and a bacterial metabolite [1] [2].		Others
T72236	Erythro-Austrobailignan-6		Others
	Erythro-Austrobailignan-6, an orally active anti-cancer agent, inhibits DNA topoisomerase I and II activity, induces cell apoptosis, and enhances the phosphorylation of p38 and JNK.		Others
T38441	Manzamine A hydrochloride		Others
	Manzamine A hydrochloride is an orally active beta-carboline alkaloid that exhibits specific inhibitory effects on GSK-3β (IC50 = 10.2 μM) and CDK-5 (IC50 = 1.5 μM). Additionally, it targets vacuolar ATPases, leading to ...		Others
TN7337	Glucoraphenin potassium		Others
	Glucoraphenin potassium, the primary orally active glucosinolate found in radish sprouts, catalyzes the induction of xenobiotic metabolizing enzymes (XMEs). It is hydrolyzed by the enzyme myrosinase into sulforaphene, wh...		Others
T72961	Falcarindiol		Others
	Falcarindiol, an orally active polyacetylenic oxylipin, not only activates PPARγ, enhancing ABCA1 expression—a cholesterol transporter—but also induces apoptosis and autophagy. This compound exhibits anti-inflammatory, a...		Others
T75427	Cholic acid sodium hydrate		Others
	Cholic acid sodium hydrate, a primary bile acid synthesized in the liver and typically conjugated with glycine or taurine, plays a crucial role in facilitating fat absorption and cholesterol excretion. This compound is o...		Others
T81222	Salvifaricin
	Salvifaricin, an orally active diterpenoid isolated from Salvia leucantha Cav. and Salvia hispanica L., significantly lowers fasting blood glucose and serum triglyceride (TG) levels, exhibiting an anti-diabetic effect [1...
T77988	Phenyl sulfate	Phenyl hydrogen sulfate	Endogenous Metabolite
	Phenyl sulfate, an orally active metabolite derived from gut microbiota, induces albuminuria and podocyte damage in diabetes experimental models. It serves as a potential disease marker and therapeutic target for diabeti...		Endogenous Metabolite
T15949	Mahanimbine		AChE
	Mahanimbine is found in the roots, leaves and stems of Murraya koenigii and is an orally active alkaloid extracted from Murraya koenigii. Bifidobacterium bifidum leaves on histopathological changes in pancreatic beta cel...		AChE
T75433	Norisoboldine hydrochloride		Others
	Norisoboldine hydrochloride, an orally active aryl hydrocarbon receptor (AhR) agonist and a prominent isoquinoline alkaloid found in Radix Linderae, is utilized for research purposes in the study of Rheumatoid Arthritis ...		Others
T60692	Masoprocol		Others
	Masoprocol (meso-Nordihydroguaiaretic acid) is a potent and orally active inhibitor of lipoxygenase. Masoprocol exhibits antihyperglycemic activity that has the potential for the type II diabetes research. In vivo, Masop...		Others
T81324	Quercetin-3-O-(2′′-O-galloyl)-β-D-glucopyranoside
	Quercetin-3-O-(2′′-O-galloyl)-β-D-glucopyranoside, an orally active phenolic compound extracted from the Geranium species, exhibits anti-inflammatory properties. It shows promise for use in treatments involving edema and...
T21266	Quinine sulfate		Others
	Quinidine is an antiarrhythmic agent. Quinidine is a potent, orally active, selective cytochrome P450db inhibitor. Quinidine is also a blocker of K + channel with an IC 50 of 19.9 μM. Quinidine has potential to be used ...		Others
T81117	Spilanthol
	Spilanthol, an orally active compound with analgesic, neuroprotective, antioxidant, antimutagenic, anti-cancer, anti-inflammatory, antimicrobial, and insecticidal properties, facilitates the induction of cAMP, thereby in...
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天然物製品

Target: Influenza Virus, Antibacterial

Prednisolone

T1560

Synonym: Predonine,Hydroretrocortine,Metacortandralone

Target: Glucocorticoid Receptor, Endogenous Metabolite

Topotecan

T5784

Synonym: NSC 609669,SKF 104864A

Target: Topoisomerase, Autophagy

Isotretinoin

T1611

Synonym: 13-cis-Retinoic acid

Target: Retinoid Receptor, Endogenous Metabolite, Autophagy

Gentamicin sulfate

T1326

Synonym: SCH9724,Gentamycin sulfate,NSC-82261

Target: ribosome, DHFR, Antibacterial, Antibiotic

NADH disodium salt

T5283

Synonym: Disodium NADH,NADH, disodium salt hydrate

Target: Others, Endogenous Metabolite

Novobiocin Sodium

T0974

Synonym: Albamycinsodium,Cathomycin,Albamycin

Target: Potassium Channel, DNA gyrase, Topoisomerase, Antibacterial, Antibiotic, ABC, Autophagy

Succinic acid

T2719

Synonym: Asuccin,Amber acid,1,2-Ethanedicarboxylic acid,Wormwood acid,Butanedioic acid,1,4-Butandioic Acid

Target: Endogenous Metabolite

Fidaxomicin

T6194

Synonym: Tiacumicin B,OPT-80,Clostomicin B1,PAR-101

Target: Apoptosis, DNA/RNA Synthesis, Antibacterial, Antibiotic

Amentoflavone

T3417

Synonym: Didemethyl-ginkgetin,Amenthoflavone,3',8''-Biapigenin

Target: Apoptosis, P450, Phospholipase, Reactive Oxygen Species, Opioid Receptor, COX, Antibacterial, RSV, Antifungal

Rhoifolin

T2755

Synonym: Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside

Target: Others, p38 MAPK, NF-κB, transporter, IGF-1R, Autophagy

Synonym: Abscisic acid,Dormin,Abscisinsaeure

Target: Others

Tauro-Obeticholic acid

Target: Reactive Oxygen Species, ROS, COX

Jatrorrhizine chloride

T4912

Synonym: Yatrorhizine chloride,Neprotine chloride

Target: Others, 5-HT Receptor, OCT, Antibacterial, AChE

Capsiate

TN2429

Synonym:

Target: Antioxidant, TRP/TRPV Channel

Valproic Acid

T7064

Synonym: Sodium valproate,2-Propylpentanoic Acid,VPA,Depakine,2-Propylvaleric Acid

Target: Mitophagy, Gamma-secretase, HIV Protease, GABA Receptor, Sodium Channel, HDAC, Autophagy

DMAPT

T11060

Synonym: Dimethylamino Parthenolide

Target: NF-κB

Corticosterone

T0948L

Synonym: 17-Deoxycortisol,11β,21-Dihydroxyprogesterone,Kendall's compound B,Corticosterone (From plants)

Target: Glucocorticoid Receptor, Endogenous Metabolite

MRE-269

T3S2007

Synonym: MRE 269,ACT-333679,MRE269

Target: Prostaglandin Receptor

Aurantiamide acetate

TJS2216

Synonym: Asperglaucide

Target: Cysteine Protease

Isomucronulatol

T3859

Synonym: 7,2'-Dihydroxy-3',4'-dimethoxyisoflavan

Target: Others

PCO371

T16442

Synonym: 2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-

Target: Thyroid hormone receptor(THR)

Tramiprosate

T0883

Synonym: Homotaurine,3-Amino-1-propanesulfonic acid,Alzhemed

Target: Beta Amyloid, GABA Receptor

Jatrorrhizine hydrochloride

T2986

Synonym:

Target: Others, 5-HT Receptor, Antibacterial, AChE

Tricaprin

T5227

Synonym: Tridecanoin,Glyceryl tridecanoate,Glycerol Tridecanoate,TG(10:0/10:0/10:0),Glycerol tricaprate

Target: Others, Endogenous Metabolite

N,N'-Dimethylthiourea

Synonym: (−)-Equol,Equol,4',7-Dihydroxyisoflavan,4',7-Isoflavandiol

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Endogenous Metabolite

Nystatin

T1678

Synonym: Stamycin,Fungicidin,Nystavescent

Target: Apoptosis, Antibiotic, Antifungal

Smilagenin

T4954L

Synonym: PYM50028,Cogane,AI3-44895,PYM 50028

Chitotriose trihydrochloride

erythro-Austrobailignan-6

T72236

Synonym:

Target: Others

Manzamine A hydrochloride

T38441

Synonym:

Target: Others

Glucoraphenin potassium

Cholic acid sodium hydrate

Synonym: Phenyl hydrogen sulfate

Target: Endogenous Metabolite

Norisoboldine hydrochloride

Quercetin-3-O-(2′′-O-galloyl)-β-D-glucopyranoside

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カタログ番号	製品名
L9850	Orally Active Compound Library		2427 compounds
	A unique collection of 2427 of orally active compounds for high-throughput screening and high-content screening.

ライブラリー

Orally Active Compound Library

L9850

Compounds: 2427

Isotope Products

カタログ番号	製品名	別名	ターゲット
T60016	VV116	GS-621763-d1,JT001	SARS-CoV , RSV
	VV116 (JT001) is a selective and orally active nucleoside antiviral agent against respiratory syncytial virus (RSV) and SARS-CoV-2 infection.		SARS-CoV , RSV
T24046	WNK-IN-11-d3	WNK inhibitor-12,WNKIN12,WNK IN 12,WNK inhibitor 12,WNK-IN-12
	WNK-IN-12 is an effective, selective, and orally active WNK1 kinase inhibitor.
T13181	Tolcapone D7	Ro 40-7592 D7	Transferase
	Tolcapone D7 is a deuterium-labeled Tolcapone. Tolcapone is a selective and orally active inhibitor of COMT.		Transferase
T12329	Ospemifene D4	FC-1271a D4	Estrogen/progestogen Receptor
	Ospemifene D4 is a deuterium labeled Ospemifene. Ospemifene is a selective and orally active modulator of estrogen receptor.		Estrogen/progestogen Receptor
T19305	Eldecalcitol-d6		Others
	Eldecalcitol is an orally active analogue of active vitamin D used in the treatment of osteoporosis. Eldecalcitol-d6 is the deuterium labeled Eldecalcitol.		Others
T12355	Palbociclib-d8	PD 0332991 D8,Palbociclib D8	CDK
	Palbociclib D8 is a deuterium labeled Palbociclib. Palbociclib is a selective and orally active inhibitor of CDK4 and CDK6 (IC50s of 11 and 16 nM, respectively).		CDK
T11817	Lansoprazole Sulfide D4		Proton pump
	Lansoprazole Sulfide D4 is a deuterium labeled Lansoprazole Sulfide. Lansoprazole Sulfide is an orally active anti-TB (Mycobacterium tuberculosis) agent with IC50 values of 0.59 μM intracellularly and 0.46 μM in broth.La...		Proton pump
T12210	Netupitant D6	CID-6451149 D6	Others
	Netupitant D6 is the deuterium labeled Netupitant, which is a selective and orally active antagonist of neurokinin-1 receptor.		Others
T10282	Aliskiren D6 Hydrochloride	SPP 100 D6 Hydrochloride,CGP60536B D6 Hydrochloride,CGP 60536 D6 Hydrochloride	Others
	Aliskiren (CGP 60536) D6 Hydrochloride is a deuterium-labeled Aliskiren. Aliskiren hemifumarate is a direct and orally active renin inhibitor (IC50: 1.5 nM).		Others
T19187	Aliskiren D6 hemifumarate	CGP 60536 D6 hemifumarate,SPP 100 D6 hemifumarate,CGP60536B D6 hemifumarate	RAAS
	Aliskiren (CGP 60536) D6 hemifumarate is a deuterium-labeled Aliskiren hemifumarate. Aliskiren hemifumarate is a direct and orally active renin inhibitor (IC50: 1.5 nM).		RAAS
T13195	Trandolapril D5	RU44570 D5	Others
	Trandolapril D5 is a deuterium labeled Trandolapril. Trandolapril is an orally active inhibitor of angiotensin converting enzyme (ACE) for hypertension and congestive heart failure (CHF).		Others
T11871	Loteprednol Etabonate D5		Others
	Loteprednol Etabonate D5, a deuterium-labeled variant of Loteprednol etabonate (LE), is an orally active, anti-inflammatory soft steroid within a distinctive class of glucocorticoids. It is deployed in optometry and opht...		Others
TMIH-0519	Selexipag Active Metabolite-d7
	Selexipag Active Metabolite-d7 is a deuterated compound of Selexipag Active Metabolite. Selexipag Active Metabolite has a CAS number of 475085-57-5. MRE-269 is an orally available and long-acting prostacyclin receptor ag...
T12521	Ponatinib-d8	AP24534 D8	Others
	Ponatinib D8 is a deuterium labeled Ponatinib. Ponatinib is an orally active inhibitor of multi-targeted kinase(Abl, PDGFRα, VEGFR2, FGFR1, and Src with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM, respectively)...		Others
T11246	Etoricoxib-d4	MK-0663 D4,L-791456 D4,Etoricoxib D4	Others
	Etoricoxib D4 is a non steroidal anti-inflammatory agent, acting as a selective and orally active COX-2 inhibitor, with IC50s of 1.1 μM and 116 μM for COX-2 and COX-1 in human whole blood.Etoricoxib D4 is a deuterium la...		Others
T11197	Enclomiphene D4 hydrochloride	(E)-Clomiphene D4 hydrochloride,Enclomifene D4 hydrochloride,trans-Clomiphene D4 hydrochloride	Others
	Enclomiphene D4 hydrochloride ((E)-Clomiphene D4 hydrochloride; trans-Clomiphene D4 hydrochloride; Enclomifene D4 hydrochloride) is a potent and orally active oestrogen receptor antagonist, with antioestrogenic property...		Others
T72818	Dosimertinib-d3
	Dosimertinib-d3 is a potent, orally active inhibitor of EGFR, known to reduce the expression of p-EGFR and p-ERK proteins, thereby exhibiting antiproliferative and anti-tumor effects. It holds promise for research into n...
TMIH-0394	Nirmatrelvir-d9
	Nirmatrelvir-d9 is a deuterated compound of Nirmatrelvir. Nirmatrelvir has a CAS number of 2628280-40-8. PF-07321332 is a potent and orally active inhibitor of SARS-CoV 3C-like protease (3CLPRO) .
TMIH-0602	Vonoprazan-d4
	Vonoprazan-d4 is a deuterated compound of Vonoprazan. Vonoprazan has a CAS number of 881681-00-1. Vonoprazan is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduoden...
TMIH-0601	Vonoprazan-d3
	Vonoprazan-d3 is a deuterated compound of Vonoprazan. Vonoprazan has a CAS number of 881681-00-1. Vonoprazan is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduoden...
T71055	Albendazole-d7
	Albendazole-d7 is intended for use as an internal standard for the quantification of albendazole by GC- or LC-MS. Albendazole is an orally bioavailable benzimidazole anthelmintic that is active against a variety of helmi...
TMID-0032	Oseltamivir-d3
	Oseltamivir-d3 is a deuterated compound of Oseltamivir. Oseltamivir has a CAS number of 196618-13-0. Oseltamivir (GS 4104) is an orally active and highly potent viral neuraminidase (NA) with antiviral activity, inhibits ...
TMIH-0087	Amlodipine-d4 Maleate (Racemic)
	Amlodipine-d4 Maleate (Racemic) is a deuterated compound of Amlodipine Maleate (Racemic). Amlodipine Maleate (Racemic) has a CAS number of 88150-47-4. Amlodipine maleate is an orally active dihydropyridine calcium channe...
TMIH-0159	Citalopram-d6
	Citalopram-d6 is a deuterated compound of Citalopram. Citalopram has a CAS number of 59729-33-8. Citalopram (Lu 10-171 is an orally active, selective serotonin reuptake inhibitor (SSRI), a selective 5-hydroxytryptamine r...
TMIH-0091	AOH-d3
	AOH-d3 is a deuterated compound of AOH. AOH has a CAS number of 2089314-64-5. AOH1996 is an orally active ligand for the replicasome component PCNA (proliferating cell nuclear antigen), targeting the transcription-replic...
TMIH-0025	13C-d3-AOH1996
	13C-d3-AOH1996 is the 13C and deuterated compound of AOH1996. 13C-AOH1996 has a CAS number of 2089314-64-5. AOH1996 is an orally active ligand for the replicasome component PCNA (proliferating cell nuclear antigen), targ...